# Gene ID Len protein Mutant Summary functional categories Description summary Bcin01g00010 310 SM cluster BOA Bcboa1, Putative botcinic acid (BoA) biosynthetic gene, NmrA-like family Bcin01g00020 529 SM cluster BOA Bcboa2, Putative botcinic acid (BoA) biosynthetic gene, flavin-binding monooxygenase-like Bcin01g00030 506 SM cluster BOA Bcboa3, Putative botcinic acid (BoA) biosynthetic gene, cytochrome P450 Bcin01g00040 495 SM cluster BOA Bcboa4, Putative botcinic acid (BoA) biosynthetic gene, cytochrome P450 Bcin01g00050 375 SM cluster BOA Bcboa5, Putative botcinic acid (BoA) biosynthetic gene, alcohol dehydrogenase GroES-like domain Bcin01g00060 2460 yes SM cluster BOA (KE) Bcboa6,Bcpks6, Polyketide synthase, in botcinid acid biosynthesis gene cluster Bcin01g00070 535 SM cluster BOA Bcboa7, Putative botcinic acid (BoA) biosynthetic gene, P450 monooxygenase Bcin01g00080 789 SM cluster BOA Bcboa8, Putative botcinic acid (BoA) biosynthetic gene, FAD-binding domain Bcin01g00090 2330 yes SM cluster BOA (KE) Bcboa9,Bcpks9, Polyketide synthase, in botcinid acid biosynthesis gene cluster Bcin01g00100 272 SM cluster BOA Bcboa10, Putative botcinic acid (BoA) biosynthetic gene, thioesterase domain Bcin01g00110 470 SM cluster BOA Bcboa11, Putative botcinic acid (BoA) biosynthetic gene, transferase family Bcin01g00120 220 SM cluster BOA Bcboa12, Putative botcinic acid (BoA) biosynthetic gene Bcin01g00130 574 yes Zn2/Cys6 transcription factor//SM cluster BOA Bcboa13, Putative botcinic acid (BoA) biosynthetic gene, Zn2/Cys6 transcription factor Bcin01g00140 179 Fungal trans transcription factor//SM cluster BOA//Effector(V2)|Effector(V1) Bcboa15, Putative botcinic acid (BoA) biosynthetic gene, fungal specific transcription factor domain Bcin01g00150 77 SM cluster BOA//Effector(V2)|Effector(V1) Bcboa16, Putative botcinic acid (BoA) biosynthetic gene, NAD dependent epimerase/dehydratase family Bcin01g00160 274 SM cluster BOA//Effector(V1) Bcboa17, Putative botcinic acid (BoA) biosynthetic gene, short chain dehydrogenase Bcin01g00170 623 Amino acid/polyamine transporter I + Amino acid permease, fungi + Amino acid permease, conserved site + Amino acid permease/ SLC12A domain Bcin01g00180 1442 ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase + Alpha-factor-transporting ATPase Ste6 Bcin01g00190 331 "Bcmho1, similar to yeast MHO1, Protein of unknown function; inhibits haploid invasive growth when overexpressed; synthetically lethal with phospholipase C (PLC1); expression induced by mild heat-stress on a non-fermentable carbon source, upon entry into stationary phase and upon nitrogen deprivation; repressed by inosine and choline in an Opi1p-dependent manner; highly conserved from bacteria to human; Memo, the human homolog, is an ErbB2 interacting protein with an essential function in cell motility [Source:SGD;Acc:S000003768]" Bcin01g00200 629 Protease//SignalP-noTM Metal-dependent hydrolase, composite domain + Amidohydrolase 3 + Metal-dependent hydrolase Bcin01g00210 567 "Bcilv1, similar to yeast ILV1, Threonine deaminase, catalyzes first step in isoleucine biosynthesis; expression is under general amino acid control; ILV1 locus exhibits highly positioned nucleosomes whose organization is independent of known ILV1 regulation [Source:SGD;Acc:S000000888]" Bcin01g00220 175 "Bcrcf1, similar to yeast RCF1, Cytochrome c oxidase subunit; required for assembly of the Complex III-Complex IV supercomplex, and for assembly of Cox13p and Rcf2p into cytochrome c oxidase; similar to Rcf2p, and either Rcf1p or Rcf2p is required for late-stage assembly of the Cox12p and Cox13p subunits and for cytochrome c oxidase activity; required for growth under hypoxic conditions; member of the hypoxia induced gene family; C. elegans and human orthologs are functional in yeast [Source:SGD;Acc:S000004492]" Bcin01g00230 611 "Bcrtc5, similar to yeast RTC5, Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; null mutation suppresses cdc13-1 temperature sensitivity [Source:SGD;Acc:S000005644]" Bcin01g00240 688 Heterokaryon incompatibility Bcin01g00250 393 Bcin01g00260 590 FAD-linked oxidase, C-terminal + FAD linked oxidase, N-terminal + FAD-linked oxidase-like, C-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 + Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain + Vanillyl-alcohol oxidase, C-terminal subdomain 2 Bcin01g00270 350 Protease//Effector(V2)|Effector(V1) Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin01g00280 1244 PAS domain + Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily Bcin01g00290 339 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin01g00300 340 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin01g00310 298 Ankyrin repeat + Ankyrin repeat-containing domain Bcin01g00320 331 SignalP-noTM Bcin01g00330 868 "Bcpsy2, similar to yeast PSY2, Subunit of protein phosphatase PP4 complex; Pph3p and Psy2p form the active complex, Psy4p may provide additional substrate specificity; regulates recovery from the DNA damage checkpoint, the gene conversion- and single-strand annealing-mediated pathways of meiotic double-strand break repair and efficient Non-Homologous End-Joining (NHEJ) pathway; Pph3p and Psy2p localize to foci on meiotic chromosomes; putative homolog of mammalian R3 [Source:SGD;Acc:S000005145]" Bcin01g00340 392 CAZy : GT2 "Bcalg5, similar to yeast ALG5, UDP-glucose:dolichyl-phosphate glucosyltransferase; involved in asparagine-linked glycosylation in the endoplasmic reticulum [Source:SGD;Acc:S000006148]" Bcin01g00350 305 Fatty acid hydroxylase Bcin01g00360 500 "Bcerg1, similar to yeast ERG1, Squalene epoxidase; catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine [Source:SGD;Acc:S000003407]" Bcin01g00370 130 Effector(V2)|Effector(V1) "Bcpfy1, similar to yeast PFY1, Profilin; binds actin, phosphatidylinositol 4,5-bisphosphate, and polyproline regions; involved in cytoskeleton organization; required for normal timing of actin polymerization in response to thermal stress; protein abundance increases in response to DNA replication stress; highly conserved protein; human PFN1 (profilin 1) complements temperature sensitive pfy1 mutants, PFN1 mutations are a rare cause of ALS [Source:SGD;Acc:S000005648]" Bcin01g00380 987 Bcin01g00390 341 "Bcypt10, similar to yeast YPT10, Rab family GTP-binding protein; contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles [Source:SGD;Acc:S000000468]" Bcin01g00400 495 "Bccyb2, similar to yeast CYB2, Cytochrome b2 (L-lactate cytochrome-c oxidoreductase); component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions [Source:SGD;Acc:S000004518]" Bcin01g00410 325 Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin01g00420 739 "Bcist2, similar to yeast IST2, Cortical ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to the plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process [Source:SGD;Acc:S000000290]" Bcin01g00430 1018 SH3 domain Bcin01g00440 1860 "Bcfas2, similar to yeast FAS2, Alpha subunit of fatty acid synthetase; complex catalyzes the synthesis of long-chain saturated fatty acids; contains the acyl-carrier protein domain and beta-ketoacyl reductase, beta-ketoacyl synthase and self-pantetheinylation activities [Source:SGD;Acc:S000006152]" Bcin01g00450 2100 Acyl transferase domain + MaoC-like domain + Fatty acid synthase + Domain of unknown function DUF1729 + Aldolase-type TIM barrel + Acyl transferase + Acyl transferase/acyl hydrolase/lysophospholipase + Fatty acid synthase, beta subunit, fungi + Polyketide synthase, acyl transferase domain + HotDog domain + Starter unit:ACP transacylase Bcin01g00460 2018 "Bcslh1, similar to yeast SLH1, Putative RNA helicase related to Ski2p; involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses [Source:SGD;Acc:S000003503]" Bcin01g00470 197 Effector(V2)|Effector(V1) "Bcykt6, similar to yeast YKT6, Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus [Source:SGD;Acc:S000001679]" Bcin01g00480 139 "Bcgot1, similar to yeast GOT1, Homodimeric protein that is packaged into COPII vesicles; cycles between the ER and Golgi; involved in secretory transport but not directly required for aspects of transport assayed in vitro; may influence membrane composition [Source:SGD;Acc:S000004906]" Bcin01g00490 189 Effector(V2)|Effector(V1) "Bcies6, similar to yeast IES6, Component of the INO80 chromatin remodeling complex; critical for INO80 function; involved in regulation of chromosome segregation and maintenance of normal centromeric chromatin structure; human ortholog INO80C is a member of the human INO80 complex; implicated in DNA repair based on genetic interactions with RAD52 epistasis genes [Source:SGD;Acc:S000000770]" Bcin01g00500 72 Effector(V1) "Bcdad4, similar to yeast DAD4, Essential subunit of the Dam1 complex (aka DASH complex); complex couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis [Source:SGD;Acc:S000007604]" Bcin01g00510 751 "Bcarp5, similar to yeast ARP5, Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; promotes nucleosome shifts in the 3 prime direction [Source:SGD;Acc:S000005004]" Bcin01g00520 285 Bzip transcription factor Basic-leucine zipper domain Bcin01g00530 953 Bcin01g00540 698 "Bcnca2, similar to yeast NCA2, Protein that regulates expression of Fo-F1 ATP synthase subunits; involved in the regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; functions with Nca3p [Source:SGD;Acc:S000006359]" Bcin01g00550 203 yes Effector(V2)|Effector(V1) Bcsas1, Rab GTPase Bcin01g00560 438 Bcin01g00570 729 AAA+ ATPase domain + ATPase, AAA-type, core + ATPase, AAA-type, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin01g00580 297 Caleosin Bcin01g00590 228 Effector(V2) Transcriptional coactivator/pterin dehydratase Bcin01g00600 439 Bcin01g00610 854 Effector(V1) Bcin01g00620 557 Effector(V2)|Effector(V1) Bcin01g00630 417 Transporter Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin01g00640 572 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin01g00650 520 Protease Amidohydrolase 1 + Metal-dependent hydrolase, composite domain + Guanine deaminase + Metal-dependent hydrolase Bcin01g00660 1513 "Bcnte1, similar to yeast NTE1, Serine esterase; homolog of human neuropathy target esterase (NTE); Nte1p-mediated phosphatidylcholine turnover influences transcription factor Opi1p localization, affecting transcriptional regulation of phospholipid biosynthesis genes [Source:SGD;Acc:S000004524]" Bcin01g00670 310 "Bcsui2, similar to yeast SUI2, Alpha subunit of the translation initiation factor eIF2; eIF2 is involved in identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003767]" Bcin01g00680 101 Effector(V2)|Effector(V1) Bcin01g00690 150 Bcin01g00700 219 Bcin01g00710 454 yes Bcaqp7, Aquaporin Bcin01g00720 929 SignalP-noTM Zinc finger, RING-type + Protease-associated domain, PA + Zinc finger, RING-CH-type + Zinc finger, RING/FYVE/PHD-type Bcin01g00730 401 Vacuolar protein sorting-associated protein 62 Bcin01g00740 206 Thioredoxin-like fold Bcin01g00750 173 Rhamnose mutarotase + Dimeric alpha-beta barrel Bcin01g00760 282 Uncharacterised protein family UPF0405 + P-loop containing nucleoside triphosphate hydrolase Bcin01g00770 94 Ribosomal protein L37e + Ribosomal protein L37ae/L37e + Zinc-binding ribosomal protein + Ribosomal protein L37e, conserved site Bcin01g00780 1273 Domain of unknown function DUF221 + Protein of unknown function DUF3779, phosphate metabolism + Domain of unknown function DUF4463 + Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain Bcin01g00790 198 SignalP-noTM Bcin01g00800 710 SignalP-noTM Bclcc8, Laccase Bcin01g00810 717 "Bcqns1, similar to yeast QNS1, Glutamine-dependent NAD(+) synthetase; essential for the formation of NAD(+) from nicotinic acid adenine dinucleotide [Source:SGD;Acc:S000001116]" Bcin01g00820 220 "Bcimp2, similar to yeast IMP2, Catalytic subunit of mitochondrial inner membrane peptidase complex; required for maturation of mitochondrial proteins of the intermembrane space; complex contains two catalytic subunits (Imp1p and Imp2p that differ in substrate specificity), and Som1p [Source:SGD;Acc:S000004638]" Bcin01g00830 568 SignalP-noTM "Bcgdt1, similar to yeast GDT1, Protein of unknown function involved in calcium homeostasis; localizes to the cis- and medial-Golgi apparatus; GFP-fusion protein localizes to the vacuole; TMEM165, a human gene which causes Congenital Disorders of Glycosylation is orthologous and functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression reduced in a gcr1 null mutant [Source:SGD;Acc:S000000391]" Bcin01g00840 977 Bcin01g00850 461 Bcin01g00860 285 Bcin01g00870 792 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g00880 340 "Bctum1, similar to yeast TUM1, Rhodanese domain sulfur transferase; accepts persulfite from Nfs1p and transfers it to Uba4p in the pathway for 2-thiolation of the wobble uridine base of tRNAs; also stimulates sulfur transfer by Nfs1p; may be mitochondrially localized [Source:SGD;Acc:S000005777]" Bcin01g00890 96 Effector(V2)|Effector(V1) Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Anaphase-promoting complex subunit 11 Bcin01g00900 394 SignalP-noTM//Effector(V2) Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin01g00910 390 Bcin01g00920 138 Effector(V1) Bcin01g00930 206 SignalP-noTM//Effector(V1) "Bcfpr2, similar to yeast FPR2, Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase); binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking; relocalizes from nucleus to vacuole upon DNA replication stress [Source:SGD;Acc:S000002927]" Bcin01g00940 315 Bcin01g00950 377 yes Bcaqp2, Aquaporin Bcin01g00960 327 Bcin01g00970 559 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin01g00980 262 Ribosomal protein S5 + Ribosomal protein S5, C-terminal + Ribosomal protein S5, eukaryotic/archaeal + Ribosomal protein S5, N-terminal + Double-stranded RNA-binding domain + Ribosomal protein S5 domain 2-type fold, subgroup + Ribosomal protein S5, N-terminal, conserved site + Ribosomal protein S5 domain 2-type fold Bcin01g00990 460 Bcin01g01000 957 Bcin01g01010 566 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin01g01020 256 Bcin01g01030 258 Bcin01g01040 897 "Bcutp4, similar to yeast UTP4, Subunit of U3-containing 90S preribosome and SSU processome complexes; involved in production of 18S rRNA and assembly of small ribosomal subunit; member of t-Utp subcomplex involved with transcription of 35S rRNA transcript; Small Subunit processome is also known as SSU processome [Source:SGD;Acc:S000002732]" Bcin01g01050 1076 Ankyrin repeat-containing domain Bcin01g01060 445 Bcin01g01070 935 Cation transporter Bcin01g01080 477 "Bcpng1, similar to yeast PNG1, Conserved peptide N-glycanase; required for deglycosylation of misfolded glycoproteins during proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p [Source:SGD;Acc:S000006017]" Bcin01g01090 265 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin01g01100 565 Bcndi1, Internal NADH dehydrogenase Bcin01g01110 260 Bcin01g01115 88 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin01g01120 461 Mitochondrial outer membrane transport complex, Sam37/metaxin + Metaxin, glutathione S-transferase domain Bcin01g01130 307 Effector(V2) Bcin01g01140 518 Uncharacterised protein family UPF0183 Bcin01g01150 1174 Kinesin motor domain + Kinesin motor domain, conserved site + Kinesin-associated microtubule-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin01g01160 1011 Zinc finger, ZZ-type + EF-hand domain + EF-hand domain pair + EF-Hand 1, calcium-binding site Bcin01g01170 495 Bcin01g01180 953 Aminoacyl-tRNA synthetase, class I, conserved site + Aminoacyl-tRNA synthetase, class Ia + Isoleucine-tRNA ligase + Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain + Aminoacyl-tRNA synthetase, class 1a, anticodon-binding + Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding + Rossmann-like alpha/beta/alpha sandwich fold Bcin01g01190 535 yes Protease//SignalP-noTM Bcap3, Aspartic proteinase Bcin01g01200 420 Bcin01g01210 385 yes Bcvic2, vegetative incompatibility 2, putative syntaxin protein containing a SNARE domain Bcin01g01220 1444 yes Bcvic1, vegetative incompatibility 1, predicted protein containing a putative serine esterase domain, a NACHT family of NTPases domain, and several Ankyrin repeats Bcin01g01230 688 "Bctrm1, similar to yeast TRM1, tRNA methyltransferase; two forms of protein are made by alternative translation starts; localizes to both nucleus and mitochondrion to produce modified base N2,N2-dimethylguanosine in tRNAs in both compartments; nuclear Trm1p is evenly distributed around inner membrane in WT, but mislocalizes as puncta near ER-nucleus junctions in spindle pole body (SPB) mutants; both Trm1p inner nuclear membrane targeting and maintenance depend upon SPB [Source:SGD;Acc:S000002527]" Bcin01g01240 261 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin01g01250 190 SignalP-TM//Effector(V2)|Effector(V1) Bcin01g01260 226 Protease//Effector(V2)|Effector(V1) ThiJ/PfpI + Class I glutamine amidotransferase-like Bcin01g01270 196 Bcin01g01280 1183 Domain of unknown function DUF676, lipase-like + Alpha/Beta hydrolase fold Bcin01g01290 778 Zinc finger, C6HC-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site + E3 ubiquitin ligase RBR family Bcin01g01300 329 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin01g01310 144 Protease//Effector(V2) Beta-lactamase-related + Beta-lactamase/transpeptidase-like Bcin01g01320 535 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin01g01330 109 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin01g01340 518 Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin01g01350 398 NAD(P)-binding domain Bcin01g01360 233 Effector(V2)|Effector(V1) Bcin01g01370 521 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g01380 266 Effector(V1) HpcH/HpaI aldolase/citrate lyase domain + Pyruvate/Phosphoenolpyruvate kinase-like domain Bcin01g01390 655 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin01g01400 278 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin01g01410 404 "Bcaat2, similar to yeast AAT2, Cytosolic aspartate aminotransferase involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells [Source:SGD;Acc:S000004017]" Bcin01g01420 457 Ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase Bcin01g01430 568 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g01440 363 Taurine catabolism dioxygenase TauD/TfdA Bcin01g01450 1486 yes Transporter BcatrO, ABC transporter BcatrO Bcin01g01460 558 Immunoglobulin-like domain Bcin01g01470 299 SignalP-noTM Bcin01g01480 374 SignalP-noTM Bcin01g01490 568 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin01g01500 509 "Bcbna4, similar to yeast BNA4, Kynurenine 3-mono oxygenase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p; putative therapeutic target for Huntington disease [Source:SGD;Acc:S000000194]" Bcin01g01510 408 Protease Peptidase M24, structural domain + Peptidase M24, methionine aminopeptidase + Peptidase M24A, methionine aminopeptidase, subfamily 1 + MYND-like zinc finger, mRNA-binding Bcin01g01520 139 Effector(V1) Cornichon + Cornichon, conserved site Bcin01g01530 525 "Bccdc40, similar to yeast CDC40, Pre-mRNA splicing factor; important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression; required for DNA synthesis during mitosis and meiosis; has WD repeats [Source:SGD;Acc:S000002772]" Bcin01g01540 162 SignalP-noTM//Effector(V2) Bcin01g01550 130 Bcin01g01560 117 Bcin01g01570 345 Protein of unknown function DUF3712 Bcin01g01580 316 Protease Trypsin-like cysteine/serine peptidase domain Bcin01g01590 84 Effector(V1) Bcin01g01600 774 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin01g01610 330 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin01g01620 383 Bcin01g01630 539 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin01g01640 577 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g01650 827 Bcin01g01660 598 Bcin01g01670 350 Bcin01g01680 722 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin01g01690 252 Cys2His2 transcription factor//Effector(V2)|Effector(V1) Zinc finger, C2H2 + Zinc finger, RING/FYVE/PHD-type + Zinc finger, C2H2-like + Zinc finger, double-stranded RNA binding Bcin01g01700 703 "Bcsac1, similar to yeast SAC1, Phosphatidylinositol phosphate (PtdInsP) phosphatase; involved in hydrolysis of PtdIns[4]P in the early and medial Golgi; regulated by interaction with Vps74p; ER localized transmembrane protein which cycles through the Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance; regulates sphingolipid biosynthesis through the modulation of PtdIns(4)P metabolism [Source:SGD;Acc:S000001695]" Bcin01g01710 221 Effector(V2)|Effector(V1) Small GTPase superfamily + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin01g01720 667 "Bcmic60, similar to yeast MIC60, Component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; Mic60p is also involved in import of intermembrane space (IMS) proteins, probably by positioning Mia40p relative to the TOM complex to receive incoming proteins; ortholog of mammalian mitofilin [Source:SGD;Acc:S000001724]" Bcin01g01730 260 F-box domain Bcin01g01740 746 ABC transporter-like + AAA+ ATPase domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase + ABC-transporter extension domain Bcin01g01750 250 Bcin01g01760 1198 CAZy : GH18FCW //SignalP-noTM Glycoside hydrolase, chitinase active site + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin01g01770 360 Bcin01g01780 243 DNA-directed RNA polymerase III, subunit Rpc31 Bcin01g01790 583 FAD-linked oxidase, C-terminal + FAD linked oxidase, N-terminal + FAD-linked oxidase-like, C-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 + Vanillyl-alcohol oxidase, C-terminal subdomain 2 Bcin01g01800 262 Ribosomal protein S4e + RNA-binding S4 domain + Ribosomal protein S4e, N-terminal + Ribosomal protein S4e, central region + Ribosomal protein S4e, N-terminal, conserved site + 40S ribosomal protein S4, C-terminal domain Bcin01g01810 1396 yes BcRDR1, RNA-dependent RNA polymerase Bcin01g01820 365 "Bchom2, similar to yeast HOM2, Aspartic beta semi-aldehyde dehydrogenase; catalyzes the second step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis [Source:SGD;Acc:S000002565]" Bcin01g01830 162 "Bcmix17, similar to yeast MIX17, Mitochondrial intermembrane space protein; required for normal oxygen consumption; contains twin cysteine-x9-cysteine motifs; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004604]" Bcin01g01840 243 Sas10/Utp3/C1D + Exosome-associated factor Rrp47/DNA strand repair C1D Bcin01g01850 504 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + Ketopantoate reductase, N-terminal domain + Ketopantoate reductase, C-terminal domain + NAD(P)-binding domain Bcin01g01860 137 PDCD5-related protein Bcin01g01870 280 "Bccoq4, similar to yeast COQ4, Protein with a role in ubiquinone (Coenzyme Q) biosynthesis; possibly functioning in stabilization of Coq7p; located on the matrix face of the mitochondrial inner membrane; component of a mitochondrial ubiquinone-synthesizing complex [Source:SGD;Acc:S000002612]" Bcin01g01880 377 "Bcrkm2, similar to yeast RKM2, Ribosomal protein lysine methyltransferase; responsible for trimethylation of the lysine residue at position 3 of Rpl12Ap and Rpl12Bp [Source:SGD;Acc:S000002606]" Bcin01g01890 403 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin01g01900 70 Effector(V2)|Effector(V1) "Bcsss1, similar to yeast SSS1, Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p); this complex forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p [Source:SGD;Acc:S000002493]" Bcin01g01910 661 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin01g01920 518 SANT/Myb domain + Homeodomain-like + Myb-like domain + Myb domain Bcin01g01930 153 Bcin01g01940 462 UBX domain + Thioredoxin-like fold + Ubiquitin-related domain Bcin01g01950 319 "Bcshy1, similar to yeast SHY1, Mitochondrial inner membrane protein required for complex IV assembly; associates with complex IV assembly intermediates and complex III/complex IV supercomplexes; similar to human SURF1 involved in Leigh Syndrome; complex IV is also known as cytochrome c oxidase [Source:SGD;Acc:S000003344]" Bcin01g01960 535 Histone-fold + Centromere protein T Bcin01g01970 281 P-loop containing nucleoside triphosphate hydrolase + Protein Cms1 Bcin01g01980 218 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Extracellular membrane protein, CFEM domain Bcin01g01990 327 "Bcnop6, similar to yeast NOP6, rRNA-binding protein required for 40S ribosomal subunit biogenesis; contains an RNA recognition motif (RRM); hydrophilin essential to overcome the stress of the desiccation-rehydration process; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes [Source:SGD;Acc:S000002372]" Bcin01g02000 199 yes Effector(V2)|Effector(V1)//Signaling pathway Bcrac, Rac-like GTPase Bcin01g02010 146 NTF2-like domain Bcin01g02020 685 "Bcrgd1, similar to yeast RGD1, GTPase-activating protein (RhoGAP) for Rho3p and Rho4p; possibly involved in control of actin cytoskeleton organization [Source:SGD;Acc:S000000464]" Bcin01g02030 1508 "Bcsrb8, similar to yeast SRB8, Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression [Source:SGD;Acc:S000000677]" Bcin01g02040 107 Uncharacterised protein family UPF0139 Bcin01g02050 169 Effector(V2)|Effector(V1) Translation initiation factor SUI1 + Eukaryotic translation initiation factor SUI1 Bcin01g02060 175 N-glycosylation protein EOS1 Bcin01g02070 271 Mitochondrial inner membrane protein Mba1 + NTF2-like domain Bcin01g02080 674 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin01g02090 311 "Bcade1, similar to yeast ADE1, N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase; required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000070]" Bcin01g02100 270 Galactose-binding domain-like + NADH:ubiquinone oxidoreductase intermediate-associated protein 30 Bcin01g02110 774 Apc5/TPR19 domain Bcin01g02120 134 Effector(V2)|Effector(V1) "Bccox13, similar to yeast COX13, Subunit VIa of cytochrome c oxidase; present in a subclass of cytochrome c oxidase complexes that may have a role in mimimizing generation of reactive oxygen species; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP; required for assembly of Rcf2p into cytochrome c oxidase - cytochrome bc1 supercomplexes [Source:SGD;Acc:S000003159]" Bcin01g02130 649 "Bcapn2, similar to yeast APN2, Class II abasic (AP) endonuclease involved in repair of DNA damage; homolog of human HAP1 and E. coli exoIII [Source:SGD;Acc:S000000115]" Bcin01g02140 376 Bcin01g02150 353 Mating-type protein ALPHA1/MAT-1/A-1 Bcin01g02160 1054 "Bcsla2, similar to yeast SLA2, Adaptor protein that links actin to clathrin and endocytosis; involved in membrane cytoskeleton assembly and cell polarization; present in the actin cortical patch of the emerging bud tip; dimer in vivo [Source:SGD;Acc:S000005187]" Bcin01g02170 949 "Bcnvj2, similar to yeast NVJ2, Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ); may be involved in sterol metabolism or signaling at the NVJ; contains a synaptotagmin-like-mitochondrial-lipid binding protein (SMP) domain; binds phosphatidylinositols and other lipids in a large-scale study; may interact with ribosomes, based on co-purification experiments [Source:SGD;Acc:S000006295]" Bcin01g02180 1710 "Bcrev3, similar to yeast REV3, Catalytic subunit of DNA polymerase zeta; involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair; forms a complex with Rev7p, Pol31p and Pol32p [Source:SGD;Acc:S000006088]" Bcin01g02190 467 "Bcslu7, similar to yeast SLU7, RNA splicing factor; required for ATP-independent portion of 2nd catalytic step of spliceosomal RNA splicing; interacts with Prp18p; contains zinc knuckle domain [Source:SGD;Acc:S000002495]" Bcin01g02200 191 Ribosomal protein S4/S9, N-terminal + RNA-binding S4 domain + Ribosomal protein S4/S9, eukaryotic/archaeal + Ribosomal protein S4, conserved site + Ribosomal protein S4/S9 Bcin01g02210 160 Ribosomal protein L21e + Translation protein SH3-like domain + Ribosomal protein L21e, conserved site Bcin01g02220 762 "Bcsec2, similar to yeast SEC2, Guanyl-nucleotide exchange factor for the small G-protein Sec4p; essential for post-Golgi vesicle transport and for autophagy; associates with the exocyst, via exocyst subunit Sec15p, on secretory vesicles [Source:SGD;Acc:S000005216]" Bcin01g02230 518 "Bcprp21, similar to yeast PRP21, Subunit of the SF3a splicing factor complex; required for spliceosome assembly [Source:SGD;Acc:S000003739]" Bcin01g02240 805 SET domain + Post-SET domain + AWS domain Bcin01g02250 377 Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin01g02260 171 Effector(V2)|Effector(V1) "Bcsnx3, similar to yeast SNX3, Sorting nexin for late-Golgi enzymes; required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p [Source:SGD;Acc:S000005884]" Bcin01g02270 280 Tetraspanin, EC2 domain Bcin01g02280 925 Zn2/Cys6 transcription factor Bcin01g02290 665 Zinc finger, DHHC-type transcription factor "Bcerf2, similar to yeast ERF2, Subunit of a palmitoyltransferase; this complex adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole; palmitoyltransferase is composed of Erf2p and Shr5p [Source:SGD;Acc:S000004236]" Bcin01g02300 137 Effector(V2)|Effector(V1) Bcin01g02310 953 yes CAZy : GT39 Bcpmt1, Protein o-mannosyltransferase, subfamily PMT1 Bcin01g02320 539 SignalP-noTM//Early secretome Lysophospholipase, catalytic domain + Acyl transferase/acyl hydrolase/lysophospholipase Bcin01g02330 248 Dienelactone hydrolase + Alpha/Beta hydrolase fold Bcin01g02340 112 Ribosomal protein L36 Bcin01g02350 113 Effector(V1) Complex 1 LYR protein + LYR motif-containing protein 2 Bcin01g02360 290 GNAT domain + Acyl-CoA N-acyltransferase Bcin01g02370 177 Effector(V2)|Effector(V1) Uncharacterised protein family Cys-rich Bcin01g02380 409 FAD dependent oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin01g02390 528 Major facilitator superfamily + Major facilitator superfamily domain Bcin01g02400 561 Bcin01g02410 395 Protease Putative lysophospholipase + Alpha/Beta hydrolase fold Bcin01g02420 563 "Bcnmt1, similar to yeast NMT1, N-myristoyl transferase; catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction [Source:SGD;Acc:S000004185]" Bcin01g02430 227 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin01g02440 447 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + NAD(P)-binding domain Bcin01g02450 446 Luciferase-like domain + Dimethyl sulphone monooxygenase SfnG Bcin01g02460 339 CAZy : CBM63 //SignalP-noTM Expansin/pollen allergen, DPBB domain + Expansin, cellulose-binding-like domain + RlpA-like double-psi beta-barrel domain Bcin01g02470 585 SignalP-noTM Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin01g02480 224 Bcin01g02490 264 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin01g02500 420 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin01g02510 310 Inositol oxygenase Bcin01g02520 905 CAZy : GT2 BcCHSIIIb, Class III chitin synthase Bcin01g02530 340 Bcin01g02540 383 Bcin01g02550 787 Ankyrin repeat + Ankyrin repeat-containing domain Bcin01g02560 642 "Bccdc14, similar to yeast CDC14, Protein phosphatase required for mitotic exit; required for rDNA segregation; located in nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to effect a decrease in CDK/B-cyclin activity and mitotic exit; required for meiosis I spindle disassembly; released from nucleolus upon entry into anaphase I of meiosis, resequestered in metaphase II, then released again upon entry into anaphase II; maintained in nucleolus by Cdc55p in early meiosis [Source:SGD;Acc:S000001924]" Bcin01g02565 107 CTAG/Pcc1 family Bcin01g02570 667 Helix-loop-helix (HLH) transcription factor Myc-type, basic helix-loop-helix (bHLH) domain Bcin01g02580 265 14-3-3 protein + 14-3-3 protein, conserved site + 14-3-3 domain Bcin01g02590 100 Effector(V2)|Effector(V1) Bcin01g02600 101 Effector(V1) ATPase inhibitor, IATP, mitochondria Bcin01g02610 668 "Bcnsp1, similar to yeast NSP1, FG-nucleoporin component of central core of the nuclear pore complex; also part of the nuclear pore complex (NPC) nuclear basket; contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier; found in stable complex with Nup82p, Gle2p and two other FG-nucleoporins (Nup159p and Nup116p); also found in stable complex with Nic96p and two other FG-nucleoproteins (Nup49p and Nup57p) [Source:SGD;Acc:S000003577]" Bcin01g02620 546 Protein of unknown function DUF5102 Bcin01g02630 418 "Bcngr1, similar to yeast NGR1, RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; interacts with Dhh1p to mediate POR1 mRNA decay; expressed in stationary phase [Source:SGD;Acc:S000000416]" Bcin01g02640 808 Cys2His2 transcription factor "Bchel2, similar to yeast HEL2, RING finger ubiquitin ligase (E3); involved in ubiquitylation and degradation of excess histones; interacts with Ubc4p and Rad53p; null mutant sensitive to hydroxyurea (HU); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; computational analysis suggests a role as a transcription factor [Source:SGD;Acc:S000002674]" Bcin01g02650 268 SWIB/MDM2 domain + Homeodomain-like + DEK, C-terminal + SWIB domain Bcin01g02660 1184 SignalP-TM "Bcire1, similar to yeast IRE1, Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]" Bcin01g02670 529 "Bccct2, similar to yeast CCT2, Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo [Source:SGD;Acc:S000001404]" Bcin01g02680 744 "Bcprt1, similar to yeast PRT1, eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3); subunit of the core complex of eIF3; essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes [Source:SGD;Acc:S000005888]" Bcin01g02690 530 Protease//SignalP-noTM//Early secretome Peptidase S28 + Alpha/Beta hydrolase fold Bcin01g02700 359 Protein of unknown function DUF3445 Bcin01g02710 134 Effector(V1) Bcin01g02720 162 Effector(V1) Protein of unknown function DUF3602 Bcin01g02730 451 yes Signaling pathway Bcvel2,BcvelB, Velvet-like 2, component of the Velvet protein complex, protein implicated in photoreponses Bcin01g02740 415 "Bcerd1, similar to yeast ERD1, Predicted membrane protein required for lumenal ER protein retention; mutants secrete the endogenous ER protein, BiP (Kar2p) [Source:SGD;Acc:S000002822]" Bcin01g02750 369 "Bcpex10, similar to yeast PEX10, Peroxisomal membrane E3 ubiquitin ligase; required for for Ubc4p-dependent Pex5p ubiquitination and peroxisomal matrix protein import; contains zinc-binding RING domain; mutations in human homolog cause various peroxisomal disorders [Source:SGD;Acc:S000002673]" Bcin01g02760 735 SET domain + Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Tetratricopeptide repeat Bcin01g02770 499 AdipoR/Haemolysin-III-related Bcin01g02780 522 Bccyp51, Eburicol 14 alpha-demethylase Bcin01g02790 549 yes BcDGAT2, Diacylglycerol O-acyl transferase 2 Bcin01g02800 711 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin01g02810 239 Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin01g02820 390 Serine-threonine protein kinase 19 Bcin01g02830 1007 "Bckip2, similar to yeast KIP2, Kinesin-related motor protein involved in mitotic spindle positioning; stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle [Source:SGD;Acc:S000006076]" Bcin01g02840 619 Bcin01g02850 427 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin01g02860 289 Bcin01g02870 421 FMN-dependent dehydrogenase + FMN-dependent alpha-hydroxy acid dehydrogenase, active site + Alpha-hydroxy acid dehydrogenase, FMN-dependent + Aldolase-type TIM barrel Bcin01g02880 367 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin01g02890 550 Zinc finger, SWIM-type Bcin01g02900 369 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin01g02910 583 Early secretome Bchap3, Phytase Bcin01g02920 270 Protease//Effector(V1) Dienelactone hydrolase + Alpha/Beta hydrolase fold Bcin01g02930 434 "Bcsmm1, similar to yeast SMM1, Dihydrouridine synthase; member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs [Source:SGD;Acc:S000005298]" Bcin01g02940 42 Bcin01g02950 543 AMP-dependent synthetase/ligase + AMP-binding enzyme C-terminal domain Bcin01g02960 190 "Bctvp23, similar to yeast TVP23, Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern [Source:SGD;Acc:S000002491]" Bcin01g02970 412 CAZy : AA11,CBM18 Chitin-binding, type 1 Bcin01g02980 419 Sec20 Bcin01g02990 97 Effector(V1) Ribosomal protein L53, mitochondrial Bcin01g03000 290 Early secretome "Bcipp1, similar to yeast IPP1, Cytoplasmic inorganic pyrophosphatase (PPase); homodimer that catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase [Source:SGD;Acc:S000000215]" Bcin01g03010 571 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin01g03020 571 Methylmalonate-semialdehyde dehydrogenase + Aldehyde dehydrogenase domain + Aldehyde dehydrogenase, cysteine active site + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain + Aldehyde dehydrogenase, C-terminal + Methylmalonate semialdehyde dehydrogenase, mitochondrial Bcin01g03030 623 Bcin01g03040 922 Bcin01g03050 695 UbiB domain + Protein kinase-like domain Bcin01g03060 319 "Bccyc3, similar to yeast CYC3, Cytochrome c heme lyase (holocytochrome c synthase); attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS) [Source:SGD;Acc:S000000037]" Bcin01g03070 250 Protein Hri1 Bcin01g03080 503 Bcin01g03090 379 Bcin01g03100 365 Bcin01g03110 591 HAT (Half-A-TPR) repeat + Tetratricopeptide-like helical domain Bcin01g03120 534 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g03130 386 Cyclin-D1-binding protein 1 Bcin01g03140 446 "Bcarp6, similar to yeast ARP6, Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A [Source:SGD;Acc:S000004075]" Bcin01g03150 224 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Germin + Cupin 1 + RmlC-like cupin domain + RmlC-like jelly roll fold Bcin01g03160 509 FMN-dependent dehydrogenase + Cytochrome b5-like heme/steroid binding domain + Alpha-hydroxy acid dehydrogenase, FMN-dependent + Aldolase-type TIM barrel + Cytochrome b5, heme-binding site Bcin01g03170 1028 Karyogamy protein, KAR9 Bcin01g03180 598 Bcin01g03190 26 Effector(V2)|Effector(V1) Bcin01g03200 23 Effector(V2)|Effector(V1) Bcin01g03210 458 CAZy : GH71FCW //SignalP-noTM Glycoside hydrolase, family 71 Bcin01g03220 915 "Bcnop14, similar to yeast NOP14, Nucleolar protein; forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits; also present in the small subunit processome complex, which is required for processing of pre-18S rRNA [Source:SGD;Acc:S000002307]" Bcin01g03230 710 Protease Peptidase S9, prolyl oligopeptidase, catalytic domain + Six-bladed beta-propeller, TolB-like + Alpha/Beta hydrolase fold Bcin01g03240 327 SignalP-noTM Bcin01g03250 322 Bcin01g03260 875 "Bcbik1, similar to yeast BIK1, Microtubule-associated protein; component of the interface between microtubules and kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; ortholog of mammalian CLIP-170 [Source:SGD;Acc:S000000534]" Bcin01g03270 288 NmrA-like domain + NAD(P)-binding domain Bcin01g03280 681 Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like Bcin01g03290 430 Bcin01g03300 243 Bcin01g03310 638 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin01g03320 227 Bcin01g03330 129 SignalP-noTM//Effector(V1) Bcin01g03340 225 Effector(V2)|Effector(V1) Bcin01g03350 472 Major facilitator superfamily + Major facilitator superfamily domain Bcin01g03360 615 Cell shape determining protein MreB/Mrl Bcin01g03370 254 Bcin01g03380 542 Bcin01g03390 1098 CAZy : GH38 "Bcams1, similar to yeast AMS1, Vacuolar alpha mannosidase; involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway [Source:SGD;Acc:S000003124]" Bcin01g03400 516 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g03410 480 Bcin01g03420 795 Ubiquitin fusion degradation protein UFD1 + Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain Bcin01g03430 919 Histidine kinase-like ATPase, C-terminal domain + DNA mismatch repair protein, C-terminal + Ribosomal protein S5 domain 2-type fold, subgroup + DNA mismatch repair, conserved site + Ribosomal protein S5 domain 2-type fold Bcin01g03440 1100 Aminoacyl-tRNA synthetase, class I, conserved site + Aminoacyl-tRNA synthetase, class Ia + Valine-tRNA ligase + Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain + Aminoacyl-tRNA synthetase, class 1a, anticodon-binding + Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding + Rossmann-like alpha/beta/alpha sandwich fold Bcin01g03450 460 Bcin01g03460 210 Effector(V2)|Effector(V1) RNA recognition motif domain + Zinc finger, CCCH-type + RNA recognition motif domain, eukaryote + U2 auxiliary factor small subunit + Nucleotide-binding alpha-beta plait domain Bcin01g03470 557 Oxysterol-binding protein + Oxysterol-binding protein, conserved site Bcin01g03480 1237 TRP-like family + ML-like domain Bcin01g03490 1073 Bcin01g03500 1512 C2 domain + Tricalbin Bcin01g03510 601 SM cluster STC5 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin01g03520 323 yes SM cluster STC5 (KE) Bcstc5, Sesquiterpen cyclase Bcin01g03530 1138 SM cluster STC5 Bcin01g03540 683 SM cluster STC5 Bcin01g03550 303 Transporter//SM cluster STC5 Major facilitator superfamily + Major facilitator superfamily domain Bcin01g03560 246 SM cluster STC5//Effector(V1) Ada DNA repair, metal-binding + Homeodomain-like + DNA binding HTH domain, AraC-type Bcin01g03570 153 SM cluster STC5//Protease//Effector(V2)|Effector(V1) Peptidase M16 domain + Metalloenzyme, LuxS/M16 peptidase-like + Peptidase M16, N-terminal Bcin01g03580 564 Major facilitator superfamily + Major facilitator superfamily domain Bcin01g03590 542 Dihydroneopterin aldolase/epimerase domain Bcin01g03600 415 Zinc finger, PHD-type + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, PHD-type, conserved site + Zinc finger, PHD-finger + Inhibitor of growth protein, N-terminal + ING family Bcin01g03610 477 "Bchos2, similar to yeast HOS2, Histone deacetylase and subunit of Set3 and Rpd3L complexes; required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; co-localizes with Cmr1p in nuclear foci in response to DNA damage by MMS [Source:SGD;Acc:S000003162]" Bcin01g03620 215 Protein of unknown function DUF3605 Bcin01g03630 123 Effector(V2)|Effector(V1) Bcin01g03640 525 "Bcugp1, similar to yeast UGP1, UDP-glucose pyrophosphorylase (UGPase); catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP, involved in a wide variety of metabolic pathways, expression modulated by Pho85p through Pho4p; UGP1 has a paralog, YHL012W, that arose from the whole genome duplication [Source:SGD;Acc:S000001518]" Bcin01g03650 691 "Bcpib1, similar to yeast PIB1, RING-type ubiquitin ligase of the endosomal and vacuolar membranes; binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain [Source:SGD;Acc:S000002721]" Bcin01g03660 915 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin01g03670 155 Effector(V2)|Effector(V1) Plexin-like fold Bcin01g03680 94 ThiamineS/Molybdopterin converting factor subunit 1 + Beta-grasp domain + Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp + Molybdopterin synthase sulfur carrier subunit Bcin01g03690 997 "Bcdss1, similar to yeast DSS1, 3'-5' exoribonuclease; component of the mitochondrial degradosome along with the ATP-dependent RNA helicase Suv3p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs [Source:SGD;Acc:S000004900]" Bcin01g03700 194 Bcin01g03710 447 SM cluster NRPS6 Acyl-CoA N-acyltransferase + Siderophore biosynthesis protein, conserved domain Bcin01g03720 272 SM cluster NRPS6//Effector(V1) Crotonase superfamily + Enoyl-CoA hydratase/isomerase, conserved site + ClpP/crotonase-like domain Bcin01g03730 2101 SM cluster NRPS6 (KE) Bcnrps6, Nonribosomal peptide synthase Bcin01g03740 1312 Transporter//SM cluster NRPS6 ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin01g03750 709 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site Bcin01g03760 89 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin01g03770 246 GNAT domain + Acyl-CoA N-acyltransferase Bcin01g03780 694 "Bcskt5, similar to yeast SKT5, Activator of Chs3p (chitin synthase III) during vegetative growth; recruits Chs3p to the bud neck via interaction with Bni4p; SKT5 has a paralog, SHC1, that arose from the whole genome duplication [Source:SGD;Acc:S000000157]" Bcin01g03790 1218 yes BcCHSIV, Class IV chitinsynthase Bcin01g03800 131 Effector(V1) Bcin01g03810 432 SignalP-noTM Bcin01g03820 677 CAZy : GH17FCW "Bcscw11, similar to yeast SCW11, Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p [Source:SGD;Acc:S000002996]" Bcin01g03830 288 Effector(V2) Bcsod3, Fe/Mn superoxide dismutase Bcin01g03840 813 Aminotransferase class V domain + Molybdenum cofactor sulfurase, C-terminal + MOSC, N-terminal beta barrel + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase + Molybdenum cofactor sulfurase Bcin01g03850 447 Bcin01g03860 225 Effector(V2)|Effector(V1) "Bcshr3, similar to yeast SHR3, Endoplasmic reticulum packaging chaperone; required for incorporation of amino acid permeases into COPII coated vesicles for transport to the cell surface [Source:SGD;Acc:S000002371]" Bcin01g03890 322 Protein of unknown function DUF3632 Bcin01g03900 87 SignalP-noTM//Effector(V2)|Effector(V1) Bcin01g03910 116 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin01g03920 519 Bcin01g03930 201 Effector(V1) START-like domain Bcin01g03940 531 Transporter Sugar/inositol transporter + General substrate transporter + Major facilitator superfamily domain Bcin01g03950 241 Bcin01g03960 123 Effector(V1) Bcin01g03970 299 BTB/POZ-like + BTB/POZ fold Bcin01g03980 363 BTB/POZ-like + BTB/POZ fold Bcin01g03990 281 BTB/POZ-like + BTB/POZ fold Bcin01g04000 329 Ribosomal protein L24/L26, conserved site + Ribosomal protein L2 domain 2 Bcin01g04010 383 Protease//SignalP-noTM Peptidase M20 + Peptidase M20, dimerisation domain + EF-Hand 1, calcium-binding site Bcin01g04020 448 "Bccdc43, similar to yeast CDC43, Beta subunit of geranylgeranyltransferase type I; catalyzes geranylgeranylation to the cysteine residue in proteins containing a C-terminal CaaX sequence ending in Leu or Phe; has substrates important for morphogenesis [Source:SGD;Acc:S000003123]" Bcin01g04030 176 Increased loss of mitochondrial DNA protein 1 Bcin01g04040 1007 N-acetyltransferase B complex, non-catalytic subunit Bcin01g04050 82 Effector(V1) "Bccox23, similar to yeast COX23, Protein that functions in mitochondrial copper homeostasis; mitochondrial intermembrane space protein; essential for functional cytochrome oxidase expression; homologous to Cox17p; contains twin cysteine-x9-cysteine motifs [Source:SGD;Acc:S000001158]" Bcin01g04060 378 Bcin01g04070 722 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site Bcin01g04080 816 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin01g04090 257 Effector(V1) "Bcpno1, similar to yeast PNO1, Essential nucleolar protein required for pre-18S rRNA processing; interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain [Source:SGD;Acc:S000005671]" Bcin01g04100 720 "Bcmdm32, similar to yeast MDM32, Mitochondrial inner membrane protein with similarity to Mdm31p; required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34; variation between SK1 and S288C at residues 182 and 262 impacts invasive growth and mitochondrial network structure [Source:SGD;Acc:S000005673]" Bcin01g04110 368 Taurine catabolism dioxygenase TauD/TfdA Bcin01g04120 567 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g04130 1243 AAA+ ATPase domain + ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin01g04140 148 Bcin01g04150 402 Effector(V2)|Effector(V1) Bcin01g04160 544 Folylpolyglutamate synthetase + Mur ligase, C-terminal + Mur ligase, central + Folylpolyglutamate synthetase, conserved site + Folylpolyglutamate synthase, eukaryota Bcin01g04170 519 Folylpolyglutamate synthetase + Mur ligase, C-terminal + Mur ligase, central + Folylpolyglutamate synthetase, conserved site + Folylpolyglutamate synthase, eukaryota Bcin01g04180 546 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g04190 683 Bcin01g04200 760 Homeobox transcription factor Bchox5, Homeobox transcription factor Bcin01g04210 396 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin01g04220 605 Sulfatase + Alkaline phosphatase-like, alpha/beta/alpha + Alkaline-phosphatase-like, core domain + Sulfatase, conserved site Bcin01g04230 308 "Bcmet16, similar to yeast MET16, 3'-phosphoadenylsulfate reductase; reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate and free sulfite using reduced thioredoxin as cosubstrate, involved in sulfate assimilation and methionine metabolism [Source:SGD;Acc:S000006371]" Bcin01g04240 290 Bcin01g04250 1156 SignalP-noTM Bcin01g04260 482 "Bcser2, similar to yeast SER2, Phosphoserine phosphatase of the phosphoglycerate pathway; involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source [Source:SGD;Acc:S000003440]" Bcin01g04270 1684 Bcin01g04280 848 Bcin01g04290 350 Methyltransferase domain + S-adenosyl-L-methionine-dependent methyltransferase Bcin01g04300 293 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin01g04310 514 Acyltransferase 3 Bcin01g04320 89 Bcin01g04330 252 Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin01g04340 573 "Bcmet3, similar to yeast MET3, ATP sulfurylase; catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism [Source:SGD;Acc:S000003771]" Bcin01g04350 113 "Bcisd11, similar to yeast ISD11, Cysteine desulfurase (Nfs1p) activator; essential for the formation of the persulfide intermediate at the desulfurase active site during pyridoxal phosphate-dependent desulfuration of cysteine; required for mitochondrial iron-sulfur cluster biosynthesis; exclusive to eukaryotes, implicated as eukaryotic supplement to the bacterium-derived Fe-S cluster (ISC) assembly apparatus; involved in regulation of iron metabolism; member of the LYR protein family [Source:SGD;Acc:S000007237]" Bcin01g04360 803 Bcin01g04370 684 UbiB domain + Protein kinase-like domain Bcin01g04380 741 SignalP-noTM "Bcrim9, similar to yeast RIM9, Plasma membrane protein of unknown function; involved in the proteolytic activation of Rim101p in response to alkaline pH; interacts with Rim21p and Dfg16p to form a pH-sensing complex in the Rim101 pathway and is required to maintain Rim21p levels; has similarity to A. nidulans PalI; [Source:SGD;Acc:S000004667]" Bcin01g04390 542 Septin + P-loop containing nucleoside triphosphate hydrolase + Septin-type guanine nucleotide-binding (G) domain Bcin01g04400 121 Effector(V2)|Effector(V1) Bcin01g04410 636 ATP-dependent RNA helicase DEAD-box, conserved site + Helicase, C-terminal + DEAD/DEAH box helicase domain + Helicase superfamily 1/2, ATP-binding domain + RNA helicase, DEAD-box type, Q motif + P-loop containing nucleoside triphosphate hydrolase Bcin01g04420 560 AMP-dependent synthetase/ligase Bcin01g04430 557 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin01g04440 660 "Bcarp9, similar to yeast ARP9, Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation [Source:SGD;Acc:S000004636]" Bcin01g04450 401 Bcin01g04460 574 "Bcbre2, similar to yeast BRE2, Subunit of COMPASS (Set1C) complex; COMPASS methylates Lys4 of histone H3 and functions in silencing at telomeres; has a C-terminal Sdc1 Dpy-30 Interaction (SDI) domain that mediates binding to Sdc1p; similar to trithorax-group protein ASH2L [Source:SGD;Acc:S000004005]" Bcin01g04470 897 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin01g04480 456 Bcin01g04490 1247 "Bcmsh6, similar to yeast MSH6, Protein required for mismatch repair in mitosis and meiosis; forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; also involved in interstrand cross-link repair; potentially phosphorylated by Cdc28p [Source:SGD;Acc:S000002504]" Bcin01g04500 569 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin01g04510 585 SignalP-noTM Sulfatase + Arylsulfatase + Alkaline phosphatase-like, alpha/beta/alpha + Alkaline-phosphatase-like, core domain + Sulfatase, conserved site Bcin01g04520 403 Bcin01g04530 341 SM cluster CAR//Protease//SignalP-noTM Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin01g04540 338 SM cluster CAR Bop2, 2ndMetabolismCluster : PHS1, G protein-coupled receptor (GPCR) : Microbial opsin, opsin-like 2, potential green light sensor Bcin01g04550 602 SM cluster CAR Bcphd1, Phytoene dehydrogenase (Carotenogenic gene) Bcin01g04560 610 SM cluster CAR (KE) Bcphs1, Phytoene synthase Bcin01g04570 649 SM cluster CAR Bccao1, Beta-carotene cleaving and retinal-forming oxygenase Bcin01g04580 621 SM cluster CAR//SignalP-noTM Bcin01g04590 96 Bcin01g04600 302 GPR1/FUN34/yaaH Bcin01g04610 473 3'-5' exonuclease domain + Ribonuclease H-like domain Bcin01g04620 474 Ribonuclease H-like domain Bcin01g04630 231 Effector(V2)|Effector(V1) Zinc finger, RING/FYVE/PHD-type Bcin01g04640 405 Cyclin, C-terminal domain + Cyclin, N-terminal + Cyclin-like Bcin01g04650 91 Effector(V2)|Effector(V1) Bcin01g04660 1757 Bcin01g04670 316 Bcin01g04680 179 Effector(V2)|Effector(V1) Bcin01g04690 344 Bcin01g04700 1259 Bcin01g04710 680 "Bcnop7, similar to yeast NOP7, Component of several different pre-ribosomal particles; forms a complex with Ytm1p and Erb1p that is required for maturation of the large ribosomal subunit; required for exit from G0 and the initiation of cell proliferation [Source:SGD;Acc:S000003335]" Bcin01g04720 425 "Bcgab1, similar to yeast GAB1, GPI transamidase subunit; involved in attachment of glycosylphosphatidylinositol (GPI) anchors to proteins; may have a role in recognition of the attachment signal or of the lipid portion of GPI [Source:SGD;Acc:S000004451]" Bcin01g04730 111 Bcin01g04740 574 RNA polymerase I specific transcription initiation factor, RRN9 Bcin01g04750 408 Bcin01g04760 321 Bcin01g04770 157 Effector(V2) Bcin01g04780 300 Bcin01g04790 265 "Bcubc6, similar to yeast UBC6, Ubiquitin-conjugating enzyme involved in ERAD; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway; ER-associated protein degradation is also known as ERAD [Source:SGD;Acc:S000000902]" Bcin01g04800 502 "Bcsam50, similar to yeast SAM50, Component of the Sorting and Assembly Machinery (SAM) complex; the SAM (or TOB) complex is located in the mitochondrial outer membrane; the complex binds precursors of beta-barrel proteins and facilitates their outer membrane insertion; homologous to bacterial Omp85 [Source:SGD;Acc:S000004971]" Bcin01g04810 211 Effector(V2)|Effector(V1) HotDog domain Bcin01g04820 46 SignalP-noTM//Effector(V1) Bcin01g04830 277 SM 0//Effector(V2)|Effector(V1) Protein of unknown function DUF3328 Bcin01g04840 517 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g04850 576 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin01g04860 146 SM cluster DTC1 Putative oxalocrotonate tautomerase Bcin01g04870 409 SM cluster DTC1 NADH:flavin oxidoreductase/NADH oxidase, N-terminal + Aldolase-type TIM barrel Bcin01g04880 520 SM cluster DTC1 Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin01g04890 564 SM cluster DTC1 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin01g04900 225 SM cluster DTC1//Effector(V2) gstII, Glutathione S-transferase Bcin01g04910 391 yes SM cluster DTC1//Signaling pathway Btp1, Putative G protein-coupled receptor alpha Bcin01g04920 996 SM cluster DTC1 (KE) Bcdtc1, Diterpen cyclase Bcin01g04930 89 Effector(V2) Bcin01g04940 874 "Bcmsh4, similar to yeast MSH4, Protein involved in meiotic recombination; required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein [Source:SGD;Acc:S000001891]" Bcin01g04950 520 G-protein, beta subunit + WD40 repeat + Quinonprotein alcohol dehydrogenase-like superfamily + NLE + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin01g04960 420 "Bcpot1, similar to yeast POT1, 3-ketoacyl-CoA thiolase with broad chain length specificity; cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids [Source:SGD;Acc:S000001422]" Bcin01g04970 204 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin01g04980 300 Bcsdh2, Succinate dehydrogenase subunit B Bcin01g04990 173 Bcin01g05000 149 Effector(V2)|Effector(V1) Bcin01g05010 567 Major facilitator superfamily + Major facilitator superfamily domain Bcin01g05020 178 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Extracellular membrane protein, CFEM domain Bcin01g05030 73 Bcin01g05040 126 Bcin01g05050 125 Effector(V2)|Effector(V1) Bcin01g05060 969 Protease Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase + Peptidase M1, membrane alanine aminopeptidase, N-terminal + ERAP1-like C-terminal domain Bcin01g05070 180 DnaJ domain + Zinc finger, DPH-type Bcin01g05080 453 CAZy : GH145 Bcin01g05090 520 Transporter Sugar/inositol transporter + General substrate transporter + Major facilitator superfamily domain Bcin01g05100 222 Meiotic nuclear division protein 1 Bcin01g05110 818 "Bcrim8, similar to yeast RIM8, Protein involved in proteolytic activation of Rim101p; part of response to alkaline pH; interacts with ESCRT-1 subunits Stp22p and Vps28p; essential for anaerobic growth; member of the arrestin-related trafficking adaptor family [Source:SGD;Acc:S000003013]" Bcin01g05120 475 Fatty acid desaturase, type 1 Bcin01g05130 186 "Bcmrpl25, similar to yeast MRPL25, Mitochondrial ribosomal protein of the large subunit; mutation confers increased replicative lifespan [Source:SGD;Acc:S000003308]" Bcin01g05140 817 "Bcprp28, similar to yeast PRP28, RNA helicase in the DEAD-box family; involved in RNA isomerization at the 5' splice site and for exchange of U6 for U1 snRNA at the 5' splice site [Source:SGD;Acc:S000002651]" Bcin01g05150 766 "Bcdph6, similar to yeast DPH6, Diphthamide synthetase; catalyzes the last amidation step of diphthamide biosynthesis using ammonium and ATP; evolutionarily conserved in eukaryotes; dph6 mutants exhibit diphthine accumulation and resistance to sordarin, which is indicative of defects in diphthamide formation on EF2; green fluorescent protein (GFP)-tagged protein localizes to the cytoplasm; DPH6/YLR143W is not an essential gene [Source:SGD;Acc:S000004133]" Bcin01g05160 601 yes Cys2His2 transcription factor BcMsn2, Cys2His2 transcription factor Bcin01g05170 324 AdipoR/Haemolysin-III-related Bcin01g05180 182 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Bcin01g05190 293 HPP Bcin01g05200 257 "Bctgs1, similar to yeast TGS1, Trimethyl guanosine synthase, conserved nucleolar methyl transferase; converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for nucleolar assembly and splicing of meiotic pre-mRNAs; interacts with Swm2p, which may confer substrate specificity on Tgs1p [Source:SGD;Acc:S000006078]" Bcin01g05210 356 "Bcgrh1, similar to yeast GRH1, Acetylated cis-Golgi protein, involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002925]" Bcin01g05220 154 "Bcost2, similar to yeast OST2, Epsilon subunit of the oligosaccharyltransferase complex; located in the ER lumen; catalyzes asparagine-linked glycosylation of newly synthesized proteins [Source:SGD;Acc:S000005629]" Bcin01g05230 104 Effector(V1) Uncharacterised protein family UPF0136, Transmembrane Bcin01g05240 81 Effector(V2)|Effector(V1) Cytochrome c oxidase biogenesis protein Cmc1-like Bcin01g05250 116 "Bcgim4, similar to yeast GIM4, Subunit of the heterohexameric cochaperone prefoldin complex; complex binds specifically to cytosolic chaperonin and transfers target proteins to it [Source:SGD;Acc:S000000729]" Bcin01g05260 204 CBF/NF-Y/archaeal histone transcription factor "Bchap3, similar to yeast HAP3, Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; complex is heme-activated and glucose-repressed; complex is a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding [Source:SGD;Acc:S000000117]" Bcin01g05270 675 "Bcrrn3, similar to yeast RRN3, Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA; structure reveals unique HEAT repeat fold and a surface serine patch; phosphorylation of serine patch impairs cell growth and reduces RNA polymerase I binding in vitro and RNA polymerase I recruitment to the rDNA gene in vivo [Source:SGD;Acc:S000001608]" Bcin01g05280 548 Protease//SignalP-noTM//Early secretome Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin01g05290 444 BTB/POZ-like + BTB/POZ fold Bcin01g05300 285 Effector(V2) Class II aldolase/adducin N-terminal Bcin01g05310 301 SignalP-noTM Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Bcin01g05320 179 Bcin01g05330 197 SignalP-noTM Bcin01g05340 403 Protease "Bcppe1, similar to yeast PPE1, Protein with carboxyl methyl esterase activity; may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein [Source:SGD;Acc:S000001117]" Bcin01g05350 554 Protease Protein of unknown function DUF2417 + Alpha/Beta hydrolase fold Bcin01g05360 383 "Bcrfc2, similar to yeast RFC2, Subunit of heteropentameric Replication factor C (RF-C); RF-C is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon [Source:SGD;Acc:S000003829]" Bcin01g05370 519 Bcin01g05380 2224 C2 domain + Helicase, C-terminal + AAA+ ATPase domain + Sec63 domain + DEAD/DEAH box helicase domain + Winged helix-turn-helix DNA-binding domain + Helicase superfamily 1/2, ATP-binding domain + Immunoglobulin E-set + P-loop containing nucleoside triphosphate hydrolase Bcin01g05390 615 Early secretome PWWP domain Bcin01g05400 408 "Bcrcl1, similar to yeast RCL1, Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis; subunit of U3-containing 90S preribosome processome complex involved in small ribosomal subunit assembly; stimulates Bms1p GTPase and U3 binding activity; similar to RNA cyclase-like proteins but no cyclase activity detected [Source:SGD;Acc:S000005370]" Bcin01g05410 331 Domain of unknown function DUF1746, fungi Bcin01g05420 264 Bcin01g05430 508 "Bcfrs2, similar to yeast FRS2, Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase; forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar [Source:SGD;Acc:S000001872]" Bcin01g05440 345 G-patch domain + Domain of unknown function DUF4187 Bcin01g05450 891 Pentatricopeptide repeat Bcin01g05460 710 Origin recognition complex, subunit 3 Bcin01g05470 136 Effector(V1) Bcin01g05480 249 "Bcsec66, similar to yeast SEC66, Non-essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; other members are Sec63p, Sec62p, and Sec72p [Source:SGD;Acc:S000000375]" Bcin01g05490 612 "Bcnpl4, similar to yeast NPL4, Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase; assists Cdc48p in the dislocation of misfolded, polyubiquitinated ERAD substrates that are subsequently delivered to the proteasome for degradation; also involved in the regulated destruction of resident ER membrane proteins, such as HMG-CoA reductase (Hmg1/2p) and cytoplasmic proteins (Fbp1p); role in mobilizing membrane bound transcription factors by regulated ubiquitin/proteasome-dependent processing (RUP) [Source:SGD;Acc:S000000374]" Bcin01g05500 443 Bcin01g05510 167 Effector(V2) "Bcctr2, similar to yeast CTR2, Putative low-affinity copper transporter of the vacuolar membrane; mutation confers resistance to toxic copper concentrations, while overexpression confers resistance to copper starvation; regulated by nonsense-mediated mRNA decay pathway [Source:SGD;Acc:S000001218]" Bcin01g05520 180 Effector(V2)|Effector(V1) "Bcbna1, similar to yeast BNA1, 3-hydroxyanthranilic acid dioxygenase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p [Source:SGD;Acc:S000003786]" Bcin01g05530 241 Effector(V2)|Effector(V1)//Early secretome "Bcfmp41, similar to yeast FMP41, Putative protein of unknown function; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000005112]" Bcin01g05540 219 Bcin01g05550 1166 "Bccpa2, similar to yeast CPA2, Large subunit of carbamoyl phosphate synthetase; carbamoyl phosphate synthetase catalyzes a step in the synthesis of citrulline, an arginine precursor [Source:SGD;Acc:S000003870]" Bcin01g05560 502 PWI domain Bcin01g05570 199 Effector(V1) Histone H4 acetyltransferase, NuA4 complex, Eaf6 Bcin01g05580 502 F-box domain + JmjC domain + Leucine-rich repeat domain, L domain-like Bcin01g05590 398 ATP-dependent RNA helicase DEAD-box, conserved site + Helicase, C-terminal + DEAD/DEAH box helicase domain + Helicase superfamily 1/2, ATP-binding domain + RNA helicase, DEAD-box type, Q motif + P-loop containing nucleoside triphosphate hydrolase Bcin01g05600 400 Bcin01g05610 413 "Bcenv7, similar to yeast ENV7, Vacuolar membrane protein kinase; negatively regulates membrane fusion; associates with vacuolar membrane through palmitoylation of one or more cysteines in consensus sequence; vacuolar membrane association is essential to its kinase activity; mutant shows defect in CPY processing; ortholog of human serine/threonine kinase 16 (STK16) [Source:SGD;Acc:S000006157]" Bcin01g05620 255 Actin cross-linking Bcin01g05630 209 Effector(V2)|Effector(V1) Bcin01g05640 339 Bcin01g05650 284 "Bcmgm101, similar to yeast MGM101, Protein with a role in mitochondrial DNA recombinational repair; also involved in interstrand cross-link repair; binds to and catalyzes the annealing of single-stranded mtDNA; oligomerizes to form rings and filaments; related to Rad52-type recombination proteins, with limited overall similarity but sharing conserved functionally important residues; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage and mitochondrial genome maintenance [Source:SGD;Acc:S000003905]" Bcin01g05660 78 "Bccoa4, similar to yeast COA4, Twin Cx(9)C protein involved in cytochrome c oxidase organization; organization includes assembly or stability; localizes to the mitochondrial intermembrane space via the Mia40p-Erv1p system; interacts genetically with CYC1 and with cytochrome c oxidase assembly factors [Source:SGD;Acc:S000004208]" Bcin01g05670 679 "Bcbpl1, similar to yeast BPL1, Biotin:apoprotein ligase; covalently modifies proteins with the addition of biotin, required for acetyl-CoA carboxylase (Acc1p) holoenzyme formation [Source:SGD;Acc:S000002300]" Bcin01g05680 530 CAZy : GH47 //SignalP-noTM//Early secretome Glycoside hydrolase, family 47 Bcin01g05690 546 Zn(2)-C6 fungal-type DNA-binding domain Bcin01g05700 307 RTA-like protein Bcin01g05710 3007 CAZy : GT4 Bcin01g05720 762 SignalP-noTM//Early secretome Glycoside hydrolase/deacetylase, beta/alpha-barrel Bcin01g05730 340 CAZy : GH114 Glycoside-hydrolase family GH114, TIM-barrel domain + Glycoside hydrolase superfamily Bcin01g05740 260 CAZy : GH135 Spherulation-specific family 4 Bcin01g05750 436 NAD-dependent epimerase/dehydratase, N-terminal domain + UDP-glucose 4-epimerase GalE + NAD(P)-binding domain Bcin01g05760 2656 Bcin01g05770 321 Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin01g05780 892 yes Helix-loop-helix (HLH) transcription factor BcSre1, Sterol Regulatory Element-Binding Protein Bcin01g05790 1124 yes BcniiA, Similar to nitrite reductase Bcin01g05800 1108 NB-ARC + Heterokaryon incompatibility + Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Tetratricopeptide repeat + P-loop containing nucleoside triphosphate hydrolase Bcin01g05810 155 Bcin01g05820 492 SRA-YDG + PUA-like domain Bcin01g05830 643 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin01g05840 807 Effector(V2)|Effector(V1) Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin01g05850 807 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin01g05860 318 NmrA-like domain + NAD(P)-binding domain Bcin01g05870 347 NAD-dependent epimerase/dehydratase, N-terminal domain + NmrA-like domain + NAD(P)-binding domain Bcin01g05880 362 NAD(P)-binding domain Bcin01g05890 1475 Transporter Bmr1, Bmr1, ABC-transporter Bcin01g05900 378 Bcin01g05910 574 Bcin01g05920 1254 Inositol polyphosphate-related phosphatase + SAC domain + Endonuclease/exonuclease/phosphatase Bcin01g05930 901 Bchhk17, Histidine kinase - group VII Bcin01g05940 465 SignalP-noTM Fungal lipase-like domain + Alpha/Beta hydrolase fold Bcin01g05950 293 Fumarylacetoacetase, C-terminal-related Bcin01g05960 389 Bcin01g05970 486 Transferase + Chloramphenicol acetyltransferase-like domain Bcin01g05980 438 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin01g05990 78 Effector(V1) "Bcsdh6, similar to yeast SDH6, Mitochondrial protein involved in assembly of succinate dehydrogenase; has a role in maturation of the Sdh2p subunit; member of the LYR protein family; mutations in human ortholog SDHAF1 are associated with infantile leukoencephalopathy [Source:SGD;Acc:S000007605]" Bcin01g06000 1135 Bcin01g06010 391 yes CAZy : GH16FCW //SignalP-noTM//Early secretome Bccrh1, Chitin transglycosylase Bcin01g06020 1499 Rho GTPase-activating protein domain + Pleckstrin homology domain + Rho GTPase activation protein + Pleckstrin homology-like domain Bcin01g06030 1725 "Bcsgs1, similar to yeast SGS1, RecQ family nucleolar DNA helicase; role in genome integrity maintenance; regulates chromosome synapsis and meiotic joint molecule/crossover formation; stimulates DNA catenation/decatenation activity of Top3p; potential repressor of a subset of rapamycin responsive genes; rapidly lost in response to rapamycin in Rrd1p-dependent manner; similar to human BLM and WRN proteins implicated in Bloom and Werner syndromes; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000004802]" Bcin01g06040 545 Ammonium transporter + Ammonium transporter, conserved site + Ammonium transporter AmtB-like domain + Ammonium/urea transporter Bcin01g06050 344 Oxoglutarate/iron-dependent dioxygenase + Non-haem dioxygenase N-terminal domain + Isopenicillin N synthase-like Bcin01g06060 228 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin01g06070 270 "Bcsec53, similar to yeast SEC53, Phosphomannomutase; involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen [Source:SGD;Acc:S000001849]" Bcin01g06080 1204 yes BcPRO40, Presumable scaffold protein for the CW1 pathway in filamentous fungi Bcin01g06090 635 "Bccdc6, similar to yeast CDC6, Essential ATP-binding protein required for DNA replication; component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000003730]" Bcin01g06100 488 SignalP-noTM Histidine phosphatase superfamily, clade-2 + Histidine phosphatase superfamily Bcin01g06110 600 Amino acid permease, fungi + Amino acid permease, conserved site + Amino acid permease/ SLC12A domain Bcin01g06120 731 CAZy : GH47 "Bcmns1, similar to yeast MNS1, Alpha-1,2-mannosidase; involved in ER-associated protein degradation (ERAD); catalyzes the removal of one mannose residue from a glycosylated protein, converting the modification from Man9GlcNAc to Man8GlcNAc; catalyzes the last step in glycoprotein maturation in the ER and is critical for ER protein degradation [Source:SGD;Acc:S000003892]" Bcin01g06130 245 Autophagy-related protein 3 Bcin01g06140 201 Effector(V1) "Bcmsl1, similar to yeast MSL1, U2B component of U2 snRNP; involved in splicing, binds the U2 snRNA stem-loop IV in vitro but requires association of Lea1p for in vivo binding; does not contain the conserved C-terminal RNA binding domain found in other family members [Source:SGD;Acc:S000001448]" Bcin01g06150 362 "Bcarc40, similar to yeast ARC40, Subunit of the ARP2/3 complex; ARP2/3 is required for the motility and integrity of cortical actin patches [Source:SGD;Acc:S000000438]" Bcin01g06160 374 Bcin01g06170 493 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin01g06180 403 Bcin01g06190 597 Bcin01g06200 598 Homeobox transcription factor Bchox7, Homeobox transcription factor Bcin01g06210 566 Protease//SignalP-noTM Peptidase S10, serine carboxypeptidase + Peptidase S10, serine carboxypeptidase, active site + Alpha/Beta hydrolase fold Bcin01g06220 218 Effector(V2)|Effector(V1) Small GTPase superfamily + Ran GTPase + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin01g06230 237 Effector(V2)|Effector(V1) "Bcnas2, similar to yeast NAS2, Proteasome-interacting protein; involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); similar to mammalian proteasomal modulator subunit; non-essential gene; interacts with Rpn4p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001269]" Bcin01g06240 1209 Dbl homology (DH) domain Bcin01g06250 654 Lysophospholipase, catalytic domain + Acyl transferase/acyl hydrolase/lysophospholipase Bcin01g06260 1315 yes Bos1, Two-component osmo sensing histidine-kinase Bcin01g06270 1368 C2 domain + Protein of unknown function DUF810 + Munc13 homology 1 + Mammalian uncoordinated homology 13, domain 2 + Mammalian uncoordinated homology 13, subgroup, domain 2 Bcin01g06280 990 Bcin01g06290 531 BccrnA, Similar to nitrate transporter Bcin01g06300 323 yes Cys2His2 transcription factor//Signaling pathway Bcyoh1, Cys2His2 transcription factor Bcin01g06310 495 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin01g06320 259 Transporter "Bcpol30, similar to yeast POL30, Proliferating cell nuclear antigen (PCNA); functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair [Source:SGD;Acc:S000000292]" Bcin01g06330 351 Pyridoxal phosphate (active vitamin B6) biosynthesis, pyridoxal kinase + Pyridoxamine kinase/Phosphomethylpyrimidine kinase + Ribokinase-like Bcin01g06340 216 Effector(V1) "Bcdut1, similar to yeast DUT1, deoxyuridine triphosphate diphosphatase (dUTPase); catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability; also has diphosphatase activity on deoxyinosine triphosphate [Source:SGD;Acc:S000000456]" Bcin01g06350 173 Bcin01g06360 61 Bcin01g06370 543 Bcin01g06380 148 Bcin01g06390 159 Effector(V1) Bcin01g06400 175 Bcin01g06410 605 C2 domain + Rab effector Noc2 Bcin01g06420 1117 "Bcage1, similar to yeast AGE1, ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector; involved in the secretory and endocytic pathways; contains C2C2H2 cysteine/histidine motif [Source:SGD;Acc:S000002932]" Bcin01g06430 312 HotDog domain Bcin01g06440 272 Eukaryotic translation initiation factor 3 subunit J + Eukaryotic translation initiation factor 3-like domain Bcin01g06450 473 Bcenol1, Enolase Bcin01g06460 393 Bcpio6, gene with a peak of expression during the Outset of colonization (Gioti et al., 2006) Bcin01g06470 701 Protease Sugar isomerase (SIS) + Glutamine amidotransferase type 2 domain + Nucleophile aminohydrolases, N-terminal Bcin01g06480 712 Forkhead-associated (FHA) domain + Protein kinase domain + Serine/threonine-protein kinase, active site + SMAD/FHA domain + Protein kinase-like domain + Protein kinase, ATP binding site + Calcium/calmodulin-dependent/calcium-dependent protein kinase Bcin01g06490 289 SAP30-binding protein Bcin01g06500 260 Protease//Effector(V1) "Bcpre4, similar to yeast PRE4, Beta 7 subunit of the 20S proteasome [Source:SGD;Acc:S000001946]" Bcin01g06510 401 "Bcarr3, similar to yeast ARR3, Plasma membrane metalloid/H+ antiporter; transports arsenite and antimonite; required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite [Source:SGD;Acc:S000006405]" Bcin01g06520 1229 "Bcmph1, similar to yeast MPH1, 3'-5' DNA helicase involved in error-free bypass of DNA lesions; binds flap DNA in error-free bypass pathway, stimulates activity of Rad27p and Dna2p; prevents crossovers between ectopic sequences by removing substrates for Mus81-Mms4 or Rad1-Rad10 cleavage; similar to FANCM human Fanconi anemia complementation group protein that with MHF complex is involved in stabilizing and remodeling blocked replication forks; member of SF2 DExD/H superfamily of helicases [Source:SGD;Acc:S000001441]" Bcin01g06530 523 Ion channel regulatory protein, UNC-93 + Major facilitator superfamily domain Bcin01g06540 441 Glycosyl transferase, family 1 Bcin01g06550 1045 "Bchir1, similar to yeast HIR1, Subunit of the HIR complex; HIR is a nucleosome assembly complex involved in regulation of histone gene transcription; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores [Source:SGD;Acc:S000000104]" Bcin01g06560 472 Major facilitator superfamily + Major facilitator superfamily domain Bcin01g06570 780 Zn2/Cys6 + fungal trans transcription factor "Bcdal81, similar to yeast DAL81, Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism [Source:SGD;Acc:S000001462]" Bcin01g06580 543 p53-like transcription factor, DNA-binding + NDT80 DNA-binding domain Bcin01g06590 806 Bcin01g06600 379 DapA-like + Aldolase-type TIM barrel Bcin01g06610 116 Effector(V1) Bcin01g06620 1101 "Bcfap1, similar to yeast FAP1, Protein that binds to Fpr1p; confers rapamycin resistance by competing with rapamycin for Fpr1p binding; accumulates in the nucleus upon treatment of cells with rapamycin; has similarity to D. melanogaster shuttle craft and human NFX1 [Source:SGD;Acc:S000004968]" Bcin01g06630 255 Bcin01g06640 327 "Bchis1, similar to yeast HIS1, ATP phosphoribosyltransferase; a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control [Source:SGD;Acc:S000000857]" Bcin01g06650 68 Effector(V1) Ribosomal protein S28e + Nucleic acid-binding, OB-fold + Ribosomal protein S28e conserved site Bcin01g06660 278 Bcin01g06670 450 Zinc finger, C2H2, LYAR-type Bcin01g06680 56 Effector(V1) Bcin01g06690 168 Effector(V1) Bcin01g06700 315 Protease//Effector(V2)|Effector(V1) Putative lysophospholipase + Alpha/Beta hydrolase fold Bcin01g06710 1990 Dbl homology (DH) domain + Arfaptin homology (AH) domain/BAR domain Bcin01g06720 1173 "Bcest2, similar to yeast EST2, Reverse transcriptase subunit of the telomerase holoenzyme; essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia [Source:SGD;Acc:S000004310]" Bcin01g06730 897 Fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin01g06740 504 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g06750 406 Bcin01g06760 580 Effector(V2)|Effector(V1) Zinc finger, MYND-type + Domain of unknown function DUF4470 Bcin01g06770 914 RNA recognition motif domain + Zinc finger, CCCH-type + Zinc finger, C6HC-type + Nucleotide-binding alpha-beta plait domain + Zinc finger, RING/FYVE/PHD-type Bcin01g06780 117 Paired amphipathic helix Bcin01g06790 327 SignalP-noTM SGNH hydrolase-type esterase domain Bcin01g06800 497 DAHP synthetase, class II Bcin01g06810 135 Effector(V1) Bcin01g06820 396 Bcin01g06830 156 Bcin01g06840 296 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin01g06850 327 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin01g06860 686 SignalP-noTM Bcin01g06870 214 Bcin01g06880 512 "Bccox10, similar to yeast COX10, Heme A:farnesyltransferase; catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders [Source:SGD;Acc:S000006093]" Bcin01g06890 173 Effector(V2)|Effector(V1) Bcin01g06900 453 SignalP-noTM//Early secretome Purine nucleoside permease Bcin01g06910 319 Homeodomain-like + Myb-like domain Bcin01g06920 225 Bcin01g06930 455 Protease BccarA, Arginine-specific carbamoyl phosphate synthase small subunit Bcin01g06935 24 Leader peptide, Arg-2/CPA1 Bcin01g06940 669 SAP domain + Acin1, RNSP1-SAP18 binding (RSB) motif Bcin01g06950 401 Bcin01g06960 258 Effector(V1) "Bccir1, similar to yeast CIR1, Mitochondrial protein that interacts with frataxin (Yfh1p); putative ortholog of mammalian electron transfer flavoprotein complex subunit ETF-beta; may have a role in oxidative stress response [Source:SGD;Acc:S000003439]" Bcin01g06970 525 Protease//SignalP-noTM Bclip1, Similar to lipase Bcin01g06980 400 SignalP-noTM Platelet-activating factor acetylhydrolase + Alpha/Beta hydrolase fold Bcin01g06990 898 AAA+ ATPase domain + ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin01g07000 366 Putative amidoligase enzyme Bcin01g07010 148 Effector(V2)|Effector(V1) Bcin01g07020 304 RTA-like protein Bcin01g07030 393 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin01g07040 589 Bcin01g07050 1958 Armadillo-type fold + Telomere-associated protein Rif1, N-terminal + Rif1 Bcin01g07060 120 Effector(V2)|Effector(V1) Bcin01g07070 324 Aldose 1-/Glucose-6-phosphate 1-epimerase + Galactose mutarotase-like domain + Glycoside hydrolase-type carbohydrate-binding, subgroup + Glucose-6-phosphate 1-epimerase Bcin01g07080 207 Ctr copper transporter Bcin01g07090 634 FAD-binding 8 + Ferric reductase, NAD binding + Ferric reductase transmembrane component-like domain + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel + Ferric/cupric reductase transmembrane component 7 Bcin01g07100 208 Effector(V2) Bcctr1, Copper transporter 1 Bcin01g07110 496 Diacylglycerol kinase, catalytic domain + NAD kinase/diacylglycerol kinase-like domain Bcin01g07120 543 CAZy : GT31 Protein of unknown function DUF604 Bcin01g07130 298 Bcin01g07140 247 Bcin01g07150 78 Effector(V1) Bcin01g07160 227 Effector(V2)|Effector(V1) Transcription factor TFIIB, cyclin-like domain + Cyclin-like Bcin01g07170 751 Forkhead-associated (FHA) domain + SMAD/FHA domain Bcin01g07180 112 "Bcmgr2, similar to yeast MGR2, Subunit of the TIM23 translocase complex; acts to couple Tim21p with the core Tim23 translocase; absolutely required for mitochondrial import of presequence-containing proteins at elevated temperature; required for viability of cells lacking the mitochondrial genome (petite-negative phenotype) [Source:SGD;Acc:S000006019]" Bcin01g07190 593 SignalP-noTM Bclcc5, Laccase Bcin01g07200 181 SignalP-noTM Cupredoxin Bcin01g07210 788 CAZy : GH92FCW //SignalP-noTM//Early secretome Alpha-1,2-mannosidase, putative + Six-hairpin glycosidase-like + Glycosyl hydrolase family 92 + Glycoside hydrolase-type carbohydrate-binding, subgroup Bcin01g07220 1483 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin01g07230 770 Neutral/alkaline nonlysosomal ceramidase + Neutral/alkaline non-lysosomal ceramidase, N-terminal + Neutral/alkaline non-lysosomal ceramidase, C-terminal Bcin01g07240 391 "Bchgh1, similar to yeast HGH1, Nonessential protein of unknown function; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; similar to mammalian BRP16 (Brain protein 16); relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003419]" Bcin01g07250 445 CAZy : GH28PCW pectin//SignalP-noTM Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin01g07260 549 CAZy : GH43PCW hemicellulose or pectin Glycoside hydrolase, family 43 + Concanavalin A-like lectin/glucanase domain + Glycosyl hydrolase, five-bladed beta-propellor domain Bcin01g07270 522 yes Transporter Bchxt19, Putative sugar:H symporter Bcin01g07280 1133 PAP/25A-associated Bcin01g07290 721 "Bctfg1, similar to yeast TFG1, TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP74 [Source:SGD;Acc:S000003418]" Bcin01g07300 316 "Bcbud13, similar to yeast BUD13, Subunit of the RES complex; RES complex is required for nuclear pre-mRNA retention and splicing; involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern due to a specific defect in MATa1 pre-mRNA splicing which leads to haploid gene expression in diploids [Source:SGD;Acc:S000003142]" Bcin01g07310 81 Effector(V2)|Effector(V1) Bcin01g07320 1867 SignalP-noTM CND7, CalciNeurine-Dependant (CND) gene Bcin01g07330 380 CAZy : GH28PCW pectin//SignalP-noTM Bcpg5, Endopolygalacturonase Bcin01g07340 248 Bcin01g07350 432 SignalP-noTM Bcin01g07360 533 Ovarian tumour, otubain Bcin01g07370 469 Bcin01g07380 114 SignalP-noTM Bcin01g07390 310 SignalP-noTM Bcin01g07400 467 Auxin efflux carrier Bcin01g07410 284 Bcin01g07420 368 "Bcpxr1, similar to yeast PXR1, Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain [Source:SGD;Acc:S000003512]" Bcin01g07430 132 Effector(V1) Bcin01g07440 216 "Bcsvp26, similar to yeast SVP26, Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment [Source:SGD;Acc:S000001224]" Bcin01g07450 281 Effector(V1) "Bcbud23, similar to yeast BUD23, Methyltransferase; methylates residue G1575 of 18S rRNA; required for rRNA processing and nuclear export of 40S ribosomal subunits independently of methylation activity; diploid mutant displays random budding pattern [Source:SGD;Acc:S000000643]" Bcin01g07460 378 "Bcidh1, similar to yeast IDH1, Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase; complex catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle [Source:SGD;Acc:S000004982]" Bcin01g07470 156 Effector(V2)|Effector(V1) Bcin01g07480 146 SignalP-noTM//Effector(V2)|Effector(V1) Bcin01g07490 430 Ribosomal protein L50, mitochondria Bcin01g07500 392 SignalP-noTM Bcin01g07510 393 SignalP-noTM "Bcerj5, similar to yeast ERJ5, Type I membrane protein with a J domain; required to preserve the folding capacity of the endoplasmic reticulum; loss of the non-essential ERJ5 gene leads to a constitutively induced unfolded protein response [Source:SGD;Acc:S000001937]" Bcin01g07520 421 Bcin01g07530 516 CAZy : GH125 //SignalP-noTM//Early secretome Uncharacterised conserved protein UCP028846 + Six-hairpin glycosidase-like + Six-hairpin glycosidase Bcin01g07540 1050 Aminoacyl-tRNA synthetase, class Ia + Valine-tRNA ligase + Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain + Aminoacyl-tRNA synthetase, class 1a, anticodon-binding + Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding + Rossmann-like alpha/beta/alpha sandwich fold + Aminoacyl-tRNA synthetase, class I, conserved site Bcin01g07550 418 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin01g07560 285 Protein kinase-like domain Bcin01g07570 426 Bcin01g07580 1198 F-box domain + WD40/YVTN repeat-like-containing domain Bcin01g07590 506 Bcin01g07600 392 "Bctvp38, similar to yeast TVP38, Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; required for asymmetric localization of Kar9p during mitosis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern [Source:SGD;Acc:S000001796]" Bcin01g07610 738 Zinc finger, CCCH-type + Smr protein/MutS2 C-terminal + Domain of unknown function DUF1771 Bcin01g07620 319 "Bcpcd1, similar to yeast PCD1, 8-oxo-dGTP diphosphatase; prevents spontaneous mutagenesis via sanitization of oxidized purine nucleoside triphosphates; can also act as peroxisomal pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids; nudix hydrolase family member; similar E. coli MutT and human, rat and mouse MTH1 [Source:SGD;Acc:S000004141]" Bcin01g07630 189 Effector(V2)|Effector(V1) Carbonic anhydrase Bcin01g07640 367 Jacalin-like lectin domain + Aerolysin-like toxin, beta complex domain Bcin01g07650 6847 Bcin01g07660 747 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin01g07665 566 Bcin01g07670 399 Bcin01g07680 367 Nicotinamide N-methyltransferase-like + S-adenosyl-L-methionine-dependent methyltransferase Bcin01g07690 758 Armadillo-like helical + Armadillo-type fold Bcin01g07700 545 Bcin01g07710 1064 Leucine-rich repeat + Leucine-rich repeat, typical subtype + Leucine-rich repeat domain, L domain-like Bcin01g07720 92 Effector(V1) Dolichol-phosphate mannosyltransferase subunit 3 Bcin01g07730 227 Effector(V1) Oxidoreductase-like, N-terminal Bcin01g07740 899 Bcin01g07750 678 Bcin01g07760 354 NADP-dependent oxidoreductase domain Bcin01g07770 209 yes Effector(V2)|Effector(V1) Bctrx2, Thioredoxin Bcin01g07780 385 Putative RNA methyltransferase + Nucleic acid-binding, OB-fold + tRNA (guanine-N1-)-methyltransferase, N-terminal + Alpha/beta knot methyltransferases Bcin01g07790 202 Effector(V2)|Effector(V1) Bcin01g07800 788 PAP/25A-associated + Nucleotidyl transferase domain Bcin01g07810 572 Peroxin/Ferlin domain + Peroxin/Dysferlin domain Bcin01g07820 302 "Bcyip1, similar to yeast YIP1, Integral membrane protein; required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles; homolog of human YIPF4 [Source:SGD;Acc:S000003404]" Bcin01g07830 139 Effector(V2)|Effector(V1) "Bcpam16, similar to yeast PAM16, Subunit of the import motor (PAM complex); the PAM complex is a component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); forms a 1:1 subcomplex with Pam18p and inhibits its cochaperone activity; contains a J-like domain [Source:SGD;Acc:S000003640]" Bcin01g07840 531 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin01g07850 301 RTA-like protein Bcin01g07860 372 Bcin01g07870 65 Effector(V1) Bcin01g07880 330 Effector(V2)|Effector(V1) RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin01g07890 795 Acyl-CoA N-acyltransferase + Amidase signature domain Bcin01g07900 82 SignalP-noTM//Effector(V2)|Effector(V1) Bcin01g07910 700 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin01g07920 308 Effector(V2) "Bcsps19, similar to yeast SPS19, Peroxisomal 2,4-dienoyl-CoA reductase; auxiliary enzyme of fatty acid beta-oxidation; homodimeric enzyme required for growth and sporulation on petroselineate medium; expression induced during late sporulation and in the presence of oleate [Source:SGD;Acc:S000005146]" Bcin01g07930 209 Protein of unknown function DUF1772 Bcin01g07940 140 Bcin01g07950 565 yes SignalP-noTM Bclcc1, Laccase1 Bcin01g07960 294 "Bcwhi2, similar to yeast WHI2, Protein required for full activation of the general stress response; required with binding partner Psr1p, possibly through Msn2p dephosphorylation; regulates growth during the diauxic shift; negative regulator of G1 cyclin expression [Source:SGD;Acc:S000005569]" Bcin01g07970 1168 Bcin01g07980 294 GPR1/FUN34/yaaH + Protein AlcS Bcin01g07990 909 "Bckha1, similar to yeast KHA1, Putative K+/H+ antiporter; has a probable role in intracellular cation homeostasis; localized to Golgi vesicles and detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000003630]" Bcin01g08000 358 Beta-lactamase-like Bcin01g08010 213 Phosphoribosyltransferase domain + Phosphoribosyltransferase-like Bcin01g08020 366 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + NAD(P)-binding domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Bcin01g08030 748 "Bcgcn20, similar to yeast GCN20, Positive regulator of the Gcn2p kinase activity; forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA [Source:SGD;Acc:S000001905]" Bcin01g08040 447 BctubA, Beta-tubulin Bcin01g08050 412 yes Bcass1, Argininosuccinate synthase Bcin01g08060 107 Effector(V1) Bcin01g08070 225 Galactose-binding domain-like + NADH:ubiquinone oxidoreductase intermediate-associated protein 30 Bcin01g08080 291 Bzip transcription factor Basic-leucine zipper domain Bcin01g08090 126 Bcin01g08100 296 Phytanoyl-CoA dioxygenase Bcin01g08110 537 CAZy : GH27,CBM13PCW hemicellulose//SignalP-noTM Ricin B lectin domain + Glycoside hydrolase, family 27 + Glycosyl hydrolase, family 13, all-beta + Aldolase-type TIM barrel + Glycoside hydrolase superfamily Bcin01g08120 333 Spherulation-specific family 4 Bcin01g08130 428 Zinc finger, RING/FYVE/PHD-type Bcin01g08140 304 Bcin01g08150 805 Bcin01g08160 396 Bcin01g08170 316 Effector(V2)|Effector(V1) Methyltransferase type 11 + S-adenosyl-L-methionine-dependent methyltransferase Bcin01g08180 287 Homeodomain-like + Myb-like domain Bcin01g08190 464 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin01g08200 513 Protein of unknown function DUF3445 Bcin01g08210 2253 Bcin01g08220 350 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin01g08230 716 yes Cys2His2 transcription factor//Signaling pathway Bccrz1, Cys2His2 transcription factor Bcin01g08240 551 Cation efflux protein + Cation efflux protein transmembrane domain + Cation efflux protein cytoplasmic domain Bcin01g08250 927 Bcin01g08260 208 Effector(V1) "Bcrib4, similar to yeast RIB4, Lumazine synthase (DMRL synthase); catalyzes synthesis of immediate precursor to riboflavin; DMRL synthase stands for 6,7-dimethyl-8-ribityllumazine synthase [Source:SGD;Acc:S000005503]" Bcin01g08270 338 Bcin01g08280 231 Effector(V2)|Effector(V1) "Bcade8, similar to yeast ADE8, Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway [Source:SGD;Acc:S000002816]" Bcin01g08290 211 THO complex, subunit 5 Bcin01g08300 487 SignalP-noTM Cupredoxin Bcin01g08310 249 "Bcmde1, similar to yeast MDE1, 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant [Source:SGD;Acc:S000003785]" Bcin01g08320 588 SignalP-noTM "Bccne1, similar to yeast CNE1, Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast [Source:SGD;Acc:S000000054]" Bcin01g08330 425 Aminotransferase, class IV + Branched-chain amino acid aminotransferase II + Aminotransferase, class IV, conserved site Bcin01g08340 255 S-adenosyl-L-methionine-dependent methyltransferase Bcin01g08350 491 Quinolinate phosphoribosyl transferase, C-terminal + Nicotinate phosphoribosyltransferase family Bcin01g08360 820 Patatin/Phospholipase A2-related + Acyl transferase/acyl hydrolase/lysophospholipase + Triacylglycerol lipase Bcin01g08370 375 Taurine catabolism dioxygenase TauD/TfdA Bcin01g08380 293 Uncharacterised conserved protein UCP037205 Bcin01g08390 511 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin01g08400 286 SignalP-noTM Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 Bcin01g08410 189 CS domain + HSP20-like chaperone Bcin01g08420 367 "Bctfb3, similar to yeast TFB3, Subunit of TFIIH and nucleotide excision repair factor 3 complexes; involved in transcription initiation, required for nucleotide excision repair; ring finger protein similar to mammalian CAK and TFIIH subunit [Source:SGD;Acc:S000002868]" Bcin01g08430 647 ENTH/VHS + AP180 N-terminal homology (ANTH) domain + ENTH domain + Phosphoinositide-binding clathrin adaptor, domain 2 Bcin01g08440 736 "Bcmsd1, similar to yeast MSD1, Mitochondrial aspartyl-tRNA synthetase; required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene [Source:SGD;Acc:S000006025]" Bcin01g08450 119 Bcin01g08460 249 Serine hydrolase FSH + Alpha/Beta hydrolase fold Bcin01g08470 126 BolA protein Bcin01g08480 608 AMP-dependent synthetase/ligase + AMP-binding enzyme C-terminal domain Bcin01g08490 258 Effector(V1) "Bccdc33, similar to yeast CDC33, mRNA cap binding protein and translation initiation factor eIF4E; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with translation initiation factor eIF4G (Tif4631p or Tif4632p); protein abundance increases in response to DNA replication stress; mutants are defective for adhesion and pseudohyphal growth [Source:SGD;Acc:S000005499]" Bcin01g08500 187 Effector(V1) "Bcsym1, similar to yeast SYM1, Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17 [Source:SGD;Acc:S000004241]" Bcin01g08510 576 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g08520 229 Effector(V2)|Effector(V1) Bcprx4, Peroxiredoxin (AhpC/TSA family) Bcin01g08530 1038 Kelch-type beta propeller Bcin01g08540 360 Protein of unknown function DUF1769 Bcin01g08550 573 Bcin01g08560 432 CAZy : GT50 "Bcgpi14, similar to yeast GPI14, Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I; involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M [Source:SGD;Acc:S000003774]" Bcin01g08570 282 Translin + Translin, N-terminal + Translin, C-terminal Bcin01g08580 852 Bcin01g08590 554 Domain of unknown function DUF3533 Bcin01g08600 718 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin01g08610 425 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin01g08620 339 Amidohydrolase 1 + Metal-dependent hydrolase Bcin01g08630 595 Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin01g08640 582 "Bcpho89, similar to yeast PHO89, Plasma membrane Na+/Pi cotransporter; active in early growth phase; similar to phosphate transporters of Neurospora crassa; transcription regulated by inorganic phosphate concentrations and Pho4p; mutations in related human transporter genes hPit1 and hPit2 are associated with hyperphosphatemia-induced calcification of vascular tissue and familial idiopathic basal ganglia calcification [Source:SGD;Acc:S000000500]" Bcin01g08650 978 "Bccdc5, similar to yeast CDC5, Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate [Source:SGD;Acc:S000004603]" Bcin01g08660 204 Optic atrophy 3-like Bcin01g08670 219 Bcin01g08680 115 Effector(V1) Bcpio10, Gene with a peak of expression during the Outset of colonization Bcin01g08690 143 yes Signaling pathway BcnoxD, NADPH oxidase Bcin01g08700 1036 Bcin01g08710 298 Complex 1 LYR protein Bcin01g08720 138 Effector(V2)|Effector(V1) "Bcmms2, similar to yeast MMS2, Ubiquitin-conjugating enzyme variant; involved in error-free postreplication repair; forms a heteromeric complex with Ubc13p, an active ubiquitin-conjugating enzyme; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003055]" Bcin01g08730 1681 "Bcmon2, similar to yeast MON2, Protein with a role in endocytosis and vacuole integrity; peripheral membrane protein; interacts with and negatively regulates Arl1p; localizes to the endosome; member of the Sec7p family of proteins [Source:SGD;Acc:S000005241]" Bcin01g08740 418 Protease Band 7 protein + Stomatin family + Band 7, C-terminal extension Bcin01g08750 280 Zinc finger, U1-type Bcin01g08760 848 "Bcsip5, similar to yeast SIP5, Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000004748]" Bcin01g08770 390 "Bcara2, similar to yeast ARA2, NAD-dependent arabinose dehydrogenase; involved in biosynthesis of dehydro-D-arabinono-1,4-lactone; similar to plant L-galactose dehydrogenase [Source:SGD;Acc:S000004644]" Bcin01g08780 363 DAHP synthetase I/KDSA + DHAP synthase, class 1 + Aldolase-type TIM barrel Bcin01g08790 295 Bcin01g08800 173 SignalP-noTM Bcin01g08810 758 Heterokaryon incompatibility Bcin01g08820 481 Alcohol acetyltransferase Bcin01g08830 155 Effector(V2)|Effector(V1) Exonuclease VII, small subunit Bcin01g08840 542 HMG (high mobility group) transcription factor Sterile alpha motif domain + High mobility group box domain + Sterile alpha motif/pointed domain Bcin01g08850 440 "Bcmri1, similar to yeast MRI1, 5'-methylthioribose-1-phosphate isomerase; catalyzes the isomerization of 5-methylthioribose-1-phosphate to 5-methylthioribulose-1-phosphate in the methionine salvage pathway [Source:SGD;Acc:S000006322]" Bcin01g08860 514 Bcdao6, D-amino acid oxidase 6 Bcin01g08870 349 TB2/DP1/HVA22-related protein Bcin01g08880 633 Protein of unknown function DUF833 Bcin01g08890 623 Bcin01g08900 695 Copper amine oxidase + Copper amine oxidase, C-terminal + Copper amine oxidase, N2-terminal + Copper amine oxidase, N3-terminal + Copper amine oxidase, N-terminal Bcin01g08910 341 SignalP-noTM//Early secretome SGNH hydrolase-type esterase domain Bcin01g08920 681 Bcin01g08930 471 "Bctfb2, similar to yeast TFB2, Subunit of TFIIH and nucleotide excision repair factor 3 complexes; involved in transcription initiation, required for nucleotide excision repair, similar to 52 kDa subunit of human TFIIH [Source:SGD;Acc:S000006043]" Bcin01g08940 157 Effector(V2)|Effector(V1) Phenylacetic acid degradation-related domain + Thioesterase superfamily + HotDog domain Bcin01g08950 571 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin01g08960 842 UV-endonuclease UvdE + Xylose isomerase-like, TIM barrel domain Bcin01g08970 718 SignalP-noTM TRP-like family + ML-like domain Bcin01g08980 747 Bcin01g08990 303 CAZy : CE4FCW Bccda5, Chitin deacetylase Bcin01g09000 754 Citrate transporter-like domain Bcin01g09010 330 Bcin01g09020 581 SignalP-noTM Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin01g09030 369 Homocysteine S-methyltransferase Bcin01g09040 229 Effector(V2)|Effector(V1) DnaJ domain Bcin01g09050 239 Bcin01g09060 617 Prefoldin + Domain of unknown function DUF3835 Bcin01g09070 1183 F-box domain + WD40/YVTN repeat-like-containing domain Bcin01g09080 850 "Bccsc1, similar to yeast CSC1, Calcium permeable gated cation channel; may be involved in detoxification; similar to Arabidopsis CSC1 [Source:SGD;Acc:S000004231]" Bcin01g09090 492 AAA+ ATPase domain + ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin01g09100 923 CAZy : GT20 Glycosyl transferase, family 20 + Trehalose-phosphatase + HAD-superfamily hydrolase, subfamily IIB + HAD-like domain Bcin01g09110 274 Bcin01g09120 298 Protease "Bcpre10, similar to yeast PRE10, Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005889]" Bcin01g09130 284 Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin01g09140 469 Cyclin PHO80-like Bcin01g09150 229 Protease//Effector(V2)|Effector(V1) "Bcpre3, similar to yeast PRE3, Beta 1 subunit of the 20S proteasome; responsible for cleavage after acidic residues in peptides [Source:SGD;Acc:S000003538]" Bcin01g09160 215 Effector(V2)|Effector(V1) "Bcerv2, similar to yeast ERV2, Flavin-linked sulfhydryl oxidase localized to the ER lumen; involved in disulfide bond formation within the endoplasmic reticulum (ER) [Source:SGD;Acc:S000006241]" Bcin01g09170 379 Aminotransferase, class IV + Branched-chain amino acid aminotransferase II Bcin01g09180 241 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Cysteine-rich secretory protein, allergen V5/Tpx-1-related + CAP domain + Allergen V5/Tpx-1-related, conserved site Bcin01g09190 248 BTB/POZ-like + BTB/POZ fold Bcin01g09200 312 SignalP-noTM Bcin01g09210 69 Bcin01g09220 124 Effector(V1) Bcin01g09230 1221 Bcphy2, Phytochrome-like 2, Histidine kinase - group VIII, potential red light sensor Bcin01g09240 669 Cep57 centrosome microtubule-binding domain Bcin01g09250 626 Bcin01g09260 1100 CAZy : GHnc Alpha-L-rhamnosidase RhaM Bcin01g09270 277 PQ-loop repeat Bcin01g09280 320 Bcin01g09290 467 Bcin01g09300 1850 "Bcecm29, similar to yeast ECM29, Scaffold protein; assists in association of the proteasome core particle with the regulatory particle; inhibits proteasomal ATPase activity; degraded by the mature proteasome after assembly; contains HEAT-like repeats; protein increases in abundance and relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000001022]" Bcin01g09310 275 14-3-3 protein + 14-3-3 protein, conserved site + 14-3-3 domain Bcin01g09320 999 P-type ATPase + Cation-transporting P-type ATPase, N-terminal + P-type ATPase, subfamily IIA, SERCA-type + Cation-transporting P-type ATPase, C-terminal + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, transmembrane domain + P-type ATPase, cytoplasmic domain N Bcin01g09330 206 Protease//Effector(V2)|Effector(V1) "Bcpup3, similar to yeast PUP3, Beta 3 subunit of the 20S proteasome; involved in ubiquitin-dependent catabolism; human homolog is subunit C10 [Source:SGD;Acc:S000000896]" Bcin01g09340 512 UBX domain containing protein TUG/UBX4 + Ubiquitin-related domain Bcin01g09350 106 Ribosomal protein L36e Bcin01g09360 372 yes Bcccp1, Cytochrome c peroxidase Bcin01g09370 394 Bcin01g09380 322 Bcin01g09390 467 CAZy : GH128 Carbohydrate-binding WSC + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Uncharacterised protein family, glycosyl hydrolase catalytic domain Bcin01g09400 589 Bcin01g09410 112 Effector(V1) Bcin01g09420 375 Bcin01g09430 235 CAZy : CE5PCW hemicellulose//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Cutinase + Cutinase, monofunctional + Alpha/Beta hydrolase fold Bcin01g09440 612 S-adenosyl-L-methionine-dependent methyltransferase Bcin01g09450 450 yes Bclgd1, L-galactonate dehydratase Bcin01g09460 288 CAZy : GH72FCW Glucanosyltransferase + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin01g09470 469 Ubiquitin-like + Rad60/SUMO-like domain + Ubiquitin-related domain Bcin01g09480 85 Effector(V2)|Effector(V1) "Bclsm6, similar to yeast LSM6, Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA [Source:SGD;Acc:S000002786]" Bcin01g09490 295 Methyltransferase type 11 + S-adenosyl-L-methionine-dependent methyltransferase Bcin01g09500 1945 "Bcstt4, similar to yeast STT4, Phosphatidylinositol-4-kinase; functions in the Pkc1p protein kinase pathway; required for normal vacuole morphology, cell wall integrity, and actin cytoskeleton organization [Source:SGD;Acc:S000004296]" Bcin01g09510 264 Protease//Effector(V2)|Effector(V1) "Bcpre7, similar to yeast PRE7, Beta 6 subunit of the 20S proteasome [Source:SGD;Acc:S000000137]" Bcin01g09520 329 HAD-like domain Bcin01g09530 246 Alpha crystallin/Hsp20 domain + HSP20-like chaperone Bcin01g09540 117 SignalP-noTM Bcin01g09550 297 Adenylate kinase/UMP-CMP kinase + UMP-CMP kinase + P-loop containing nucleoside triphosphate hydrolase + Adenylate kinase, conserved site Bcin01g09560 423 Proteasome component (PCI) domain + Armadillo-type fold + Eukaryotic translation initiation factor 3 subunit M Bcin01g09570 628 RNA recognition motif domain + YTH domain + Nucleotide-binding alpha-beta plait domain Bcin01g09580 594 AICARFT/IMPCHase bienzyme + Methylglyoxal synthase-like domain + Cytidine deaminase-like + AICAR transformylase, insert domain + AICAR transformylase domain Bcin01g09590 483 Bcin01g09600 142 Effector(V2)|Effector(V1) "Bcmpc1, similar to yeast MPC1, Highly conserved subunit of the mitochondrial pyruvate carrier; a mitochondrial inner membrane complex comprised of Mpc1p and either Mpc2p or Mpc3p mediates mitochondrial pyruvate uptake; null mutant displays slow growth that is complemented by expression of human or mouse ortholog; mutation in human ortholog is associated with lactic acidosis and hyperpyruvatemia [Source:SGD;Acc:S000003048]" Bcin01g09610 188 Effector(V1) "Bcsmb1, similar to yeast SMB1, Core Sm protein Sm B; part of heteroheptameric complex (with Smd1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm B and Sm B' [Source:SGD;Acc:S000000831]" Bcin01g09620 175 Effector(V1) Ribosomal protein L5 + Ribosomal protein L5, conserved site + Ribosomal protein L5 domain + Ribosomal protein L5, C-terminal + Ribosomal protein L5, N-terminal Bcin01g09630 78 Effector(V1) Bcin01g09640 107 Bcin01g09650 511 "Bczwf1, similar to yeast ZWF1, Glucose-6-phosphate dehydrogenase (G6PD); catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidative stress; homolog of the human G6PD which is deficient in patients with hemolytic anemia; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005185]" Bcin01g09660 109 Effector(V2)|Effector(V1) Ribosomal protein L35A + Translation protein, beta-barrel domain + Ribosomal protein L35Ae, conserved site Bcin01g09670 383 Protein of unknown function DUF2406 Bcin01g09680 115 Effector(V2)|Effector(V1) Vacuolar ATPase assembly integral membrane protein Vma21 Bcin01g09690 1197 "Bcfun30, similar to yeast FUN30, Snf2p family member with ATP-dependent chromatin remodeling activity; has a role in silencing at the mating type locus, telomeres and centromeres; enriched at centromeres and is required for correct chromatin structure around centromeres, as well as at the boundary element of the silent HMR; recruited to DNA double-strand breaks (DSBs) where it promotes 5' strand resection of DSBs; potential Cdc28p substrate [Source:SGD;Acc:S000000017]" Bcin01g09700 1621 Histidine kinase-like ATPase, C-terminal domain Bcin01g09710 163 Effector(V2)|Effector(V1) Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin01g09720 934 yes BcFdh, FAD/FMN-containing dehydrogenase Bcin01g09730 448 Bcin01g09740 396 Beta-lactamase-like Bcin01g09750 380 Hepatocellular carcinoma-associated antigen 59 Bcin01g09760 322 HpcH/HpaI aldolase/citrate lyase domain + Citrate lyase beta subunit-like + Pyruvate/Phosphoenolpyruvate kinase-like domain Bcin01g09770 571 SignalP-noTM Bcin01g09780 1415 Pleckstrin homology domain + Pleckstrin homology-like domain Bcin01g09790 384 Protein phosphatase 2C (PP2C)-like domain Bcin01g09800 298 "Bcutp23, similar to yeast UTP23, Component of the small subunit processome; involved in 40S ribosomal subunit biogenesis; interacts with snR30 and is required for dissociation of snR30 from large pre-ribosomal particles; has homology to PINc domain protein Fcf1p, although the PINc domain of Utp23p is not required for function; essential protein [Source:SGD;Acc:S000005530]" Bcin01g09810 1247 Protein of unknown function DUF726 + Alpha/Beta hydrolase fold Bcin01g09820 177 Effector(V1) Bcin01g09830 173 Effector(V1) Bcin01g09840 330 Thioredoxin + Galactose-binding domain-like + PITH domain + Thioredoxin-like fold + Thioredoxin domain + Thioredoxin, conserved site Bcin01g09850 654 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin01g09860 542 "Bcubx5, similar to yeast UBX5, UBX domain-containing protein that interacts with Cdc48p; ubiquitin regulatory X is also known as UBX [Source:SGD;Acc:S000002738]" Bcin01g09870 708 Protein kinase domain + Protein kinase-like domain + Protein kinase, ATP binding site Bcin01g09880 712 Bcin01g09890 269 "Bcfmp32, similar to yeast FMP32, Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000001848]" Bcin01g09900 518 "Bcgcd11, similar to yeast GCD11, Gamma subunit of the translation initiation factor eIF2; involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met; mutations in human ortholog cause X-linked intellectual disability (XLID) [Source:SGD;Acc:S000000827]" Bcin01g09910 598 yes Transporter Bcmfs1, Multidrug efflux transporter Bcin01g09920 780 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin01g09930 401 Bcin01g09940 1681 "Bcchc1, similar to yeast CHC1, Clathrin heavy chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion; the light chain (CLC1) is thought to regulate function [Source:SGD;Acc:S000003174]" Bcin01g09950 1196 Biotin/lipoyl attachment + Pyruvate carboxyltransferase + Biotin-binding site + Carboxylase, conserved domain + Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain + Carbamoyl-phosphate synthase, large subunit, N-terminal + Biotin carboxylase, C-terminal + Pyruvate carboxylase + Homeodomain-like + Single hybrid motif + Rudiment single hybrid motif + ATP-grasp fold + Biotin carboxylation domain + Aldolase-type TIM barrel + ATP-grasp fold, subdomain 1 + ATP-grasp fold, subdomain 2 + Pre-ATP-grasp domain Bcin01g09960 961 CAZy : GH3PCW/FCW Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Acyl-CoA N-acyltransferase + Glycoside hydrolase superfamily Bcin01g09970 463 CAZy : CE9 //Protease Amidohydrolase 1 + Metal-dependent hydrolase, composite domain + Metal-dependent hydrolase Bcin01g09980 339 Glucosamine-6-phosphate isomerase + Glucosamine/galactosamine-6-phosphate isomerase + Glucosamine-6-phosphate isomerase, conserved site Bcin01g09990 527 Hexokinase + Hexokinase, N-terminal + Hexokinase, C-terminal Bcin01g10000 999 DNA helicase, UvrD/REP type + UvrD-like Helicase, ATP-binding domain + DNA helicase, UvrD-like, C-terminal + P-loop containing nucleoside triphosphate hydrolase Bcin01g10010 663 Zn2/Cys6 transcription factor + Cys2His2 + Fungal_trans Zn(2)-C6 fungal-type DNA-binding domain + Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin01g10020 848 Heterokaryon incompatibility Bcin01g10030 198 Bcin01g10040 498 F-box domain + Protein of unknown function DUF3506 + F-box only protein 31 Bcin01g10050 1081 "Bcspt5, similar to yeast SPT5, Component of the universally conserved Spt4/5 complex (DSIF complex); the complex has multiple roles in concert with RNA polymerases I and II, including regulation of transcription elongation, RNA processing, quality control, and transcription-coupled DNA repair [Source:SGD;Acc:S000004470]" Bcin01g10060 667 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site Bcin01g10070 405 "Bccab4, similar to yeast CAB4, Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC); subunits of this complex are: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p; probable pantetheine-phosphate adenylyltransferase (PPAT); PPAT catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate; null mutant lethality is complemented by E. coli coaD (encoding PPAT); widely conserved [Source:SGD;Acc:S000003509]" Bcin01g10080 662 F-box domain Bcin01g10090 663 Bcin01g10100 527 Bcpic7, Gene with maximal expression at Complete colonization Bcin01g10110 87 SignalP-noTM//Effector(V2)|Effector(V1) Protein of unknown function DUF1748, fungi Bcin01g10120 476 Alpha/Beta hydrolase fold Bcin01g10130 488 Protease//Early secretome "Bcdug2, similar to yeast DUG2, Component of glutamine amidotransferase (GATase II); forms a complex with Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p) [Source:SGD;Acc:S000000485]" Bcin01g10140 263 Early secretome FMN-binding split barrel + Pyridoxamine 5'-phosphate oxidase-related Bcin01g10150 407 yes Early secretome Bcpsd, Phosphatidylserine decarboxylase Bcin01g10160 762 Aromatic amino acid lyase + Phenylalanine ammonia-lyase + L-Aspartase-like + Phenylalanine/histidine ammonia-lyases, active site + Fumarase/histidase, N-terminal Bcin01g10170 469 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin01g10180 382 Bcin01g10190 311 Bcin01g10200 256 BTB/POZ-like + BTB/POZ fold Bcin01g10210 322 BTB/POZ-like + BTB/POZ fold Bcin01g10220 166 Effector(V2)|Effector(V1) Protein kinase-like domain Bcin01g10230 528 Bcin01g10240 310 "Bcatp11, similar to yeast ATP11, Molecular chaperone; required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase; N-terminally propionylated in vivo [Source:SGD;Acc:S000005259]" Bcin01g10250 550 AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain Bcin01g10260 201 Bcin01g10270 457 CAZy : GT31 Fringe-like Bcin01g10280 816 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin01g10290 618 WD40 repeat + Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + Cyclophilin-type peptidyl-prolyl cis-trans isomerase + Cyclophilin-like domain Bcin01g10300 244 FAR-17a/AIG1-like protein Bcin01g10310 1551 CAZy : GH13,GH133Energy "Bcgdb1, similar to yeast GDB1, Glycogen debranching enzyme; contains glucanotranferase and alpha-1,6-amyloglucosidase activities; required for glycogen degradation; phosphorylated in mitochondria; activity is inhibited by Igd1p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006388]" Bcin01g10320 456 Bcgpdh, Glycerol-3-phosphate dehydrogenase Bcin01g10330 375 DAHP synthetase I/KDSA + DHAP synthase, class 1 + Aldolase-type TIM barrel Bcin01g10340 323 Effector(V2) "Bccyt1, similar to yeast CYT1, Cytochrome c1; component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex [Source:SGD;Acc:S000005591]" Bcin01g10350 556 Bcin01g10360 365 HhH-GPD domain + DNA glycosylase Bcin01g10370 225 Bcin01g10380 1089 Cytochrome P450 + Oxidoreductase FAD/NAD(P)-binding + Cytochrome P450, E-class, group I + FAD-binding, type 1 + Flavodoxin/nitric oxide synthase + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel + Cytochrome P450, conserved site + NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 + Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase + Flavoprotein-like Bcin01g10390 161 Bcin01g10400 1167 Bcin01g10410 332 BTB/POZ-like + BTB/POZ fold Bcin01g10420 493 Bcin01g10430 356 Protease Alpha/beta hydrolase fold-1 + Peptidase S33 + Proline-specific peptidase + Alpha/Beta hydrolase fold Bcin01g10440 976 RNA recognition motif domain Bcin01g10450 245 SignalP-noTM Concanavalin A-like lectin/glucanase domain Bcin01g10460 343 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin01g10470 793 "Bcbem3, similar to yeast BEM3, Rho GTPase activating protein (RhoGAP); involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly [Source:SGD;Acc:S000006036]" Bcin01g10480 202 Effector(V1) "Bcrrs1, similar to yeast RRS1, Essential protein that binds ribosomal protein L11; required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; localizes to the nucleolus and in foci along nuclear periphery; cooperates with Ebp2p and Mps3p to mediate telomere clustering by binding Sir4p, but is not involved in telomere tethering; mouse homolog shows altered expression in Huntington's disease model mice [Source:SGD;Acc:S000005820]" Bcin01g10490 471 "Bcrsm23, similar to yeast RSM23, Mitochondrial ribosomal protein of the small subunit; has similarity to mammalian apoptosis mediator proteins; null mutation prevents induction of apoptosis by overproduction of metacaspase Mca1p [Source:SGD;Acc:S000003097]" Bcin01g10500 106 Cyanovirin-N Bcin01g10510 1541 Bcin01g10520 265 Protease Peptidase C48, SUMO/Sentrin/Ubl1 Bcin01g10530 361 Xylose isomerase-like, TIM barrel domain Bcin01g10540 187 Bcin01g10550 482 "Bcuba4, similar to yeast UBA4, E1-like protein that activates Urm1p before urmylation; also acts in thiolation of the wobble base of cytoplasmic tRNAs by adenylating and then thiolating Urm1p; receives sulfur from Tum1p [Source:SGD;Acc:S000001153]" Bcin01g10560 240 "Bcpam17, similar to yeast PAM17, Constituent of the TIM23 complex; proposed alternatively to be a component of the import motor (PAM complex) or to interact with and modulate the core TIM23 (Translocase of the Inner mitochondrial Membrane) complex; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001773]" Bcin01g10570 634 Chromo domain-like Bcin01g10580 309 PBP domain Bcin01g10590 372 Bcin01g10600 1245 "Bcpex1, similar to yeast PEX1, AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis [Source:SGD;Acc:S000001680]" Bcin01g10610 820 "Bcmcm7, similar to yeast MCM7, Component of the Mcm2-7 hexameric helicase complex; MCM2-7 primes origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation in S-phase; forms an Mcm4p-6p-7p subcomplex [Source:SGD;Acc:S000000406]" Bcin01g10620 126 Bcin01g10630 52 SignalP-noTM//Effector(V1) Bcin01g10640 546 Transmembrane protein 135 Bcin01g10650 355 Peroxisomal targeting signal 1 receptor family Bcin01g10660 302 "Bcsec13, similar to yeast SEC13, Structural component of 3 distinct complexes; subunit of Nup84 nuclear pore sub-complex (NPC), COPII vesicle coat, and Seh1-associated (SEA) complex; COPII vesicle coat is required for ER to Golgi transport; the Nup84 subcomplex contributes to nucleocytoplasmic transport, NPC biogenesis and processes that may require localization of chromosomes at the nuclear periphery, including transcription; homologous to human SEC13; abundance increases under DNA replication stress [Source:SGD;Acc:S000004198]" Bcin01g10670 630 F-box domain Bcin01g10680 505 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin01g10690 863 "Bcbrn1, similar to yeast BRN1, Subunit of the condensin complex; required for chromosome condensation and for clustering of tRNA genes at the nucleolus; may influence multiple aspects of chromosome transmission [Source:SGD;Acc:S000000193]" Bcin01g10700 1060 Sodium/calcium exchanger membrane region Bcin01g10710 363 "Bccaf40, similar to yeast CAF40, Component of the CCR4-NOT transcriptional complex; evolutionarily conserved; involved in controlling mRNA initiation, elongation, and degradation; binds Cdc39p [Source:SGD;Acc:S000005232]" Bcin01g10720 776 Bzip transcription factor Basic-leucine zipper domain Bcin01g10730 93 Effector(V1) Bcin01g10740 819 Cys2His2 transcription factor Zinc finger, CCCH-type + Zinc finger, C6HC-type + Zinc finger, RING/FYVE/PHD-type Bcin01g10750 430 Fatty acid desaturase, type 1 Bcin01g10760 105 Effector(V2)|Effector(V1) Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin01g10770 544 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin01g10780 458 Protease Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin01g10790 188 Effector(V2) Bcin01g10810 240 yes Bzip transcription factor BccpcA, Bzip transcription factor Bcin01g10820 929 Ankyrin repeat + Heterokaryon incompatibility + Ankyrin repeat-containing domain Bcin01g10830 206 CAZy : CE5PCW hemicellulose//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa BccutB, Cutinase B Bcin01g10840 544 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin01g10850 1280 SignalP-noTM Bcin01g10860 190 "Bcvps25, similar to yeast VPS25, Component of the ESCRT-II complex; ESCRT-II is involved in ubiquitin-dependent sorting of proteins into the endosome [Source:SGD;Acc:S000003863]" Bcin01g10870 725 Rab-GTPase-TBC domain Bcin01g10880 677 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin01g10890 872 Sterile alpha motif domain + Pleckstrin homology domain + Pleckstrin homology-like domain + Sterile alpha motif/pointed domain Bcin01g10900 121 Effector(V1) Bcin01g10910 523 Major facilitator superfamily + Major facilitator superfamily domain Bcin01g10920 553 Wax synthase domain Bcin01g10930 1258 BRCT domain + AT hook, DNA-binding motif + Microcephalin-like Bcin01g10940 575 SignalP-noTM Cytochrome P450 + Cytochrome P450, conserved site Bcin01g10950 430 "Bcjip5, similar to yeast JIP5, Protein required for biogenesis of the large ribosomal subunit; required for biogenesis of the large ribosomal subunit; interacts with proteins involved in RNA processing, ribosome biogenesis, ubiquitination and demethylation; similar to WDR55, a human WD repeat protein; essential gene [Source:SGD;Acc:S000006373]" Bcin01g10960 657 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin01g10970 802 "Bccet1, similar to yeast CET1, RNA 5'-triphosphatase involved in mRNA 5' capping; subunit of the mRNA capping enzyme, which is a heterotetramer composed of a Cet1p homodimer and two molecules of the guanylyltransferase Ceg1p; Cet1p also has a role in regulation of RNA pol II pausing at promoter-proximal sites; interaction between Cet1p and Ceg1p is required for Ceg1p nuclear import; mammalian enzyme is a single bifunctional polypeptide; CET1 has a paralog, CTL1, that arose from the whole genome duplication [Source:SGD;Acc:S000006149]" Bcin01g10980 1127 "Bcrpn2, similar to yeast RPN2, Subunit of the 26S proteasome; substrate of the N-acetyltransferase Nat1p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001337]" Bcin01g10990 569 Permease, cytosine/purines, uracil, thiamine, allantoin + Nucleobase cation symporter-1, NCS1 Bcin01g11000 1677 Cys2His2 transcription factor Bcin01g11010 558 Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin01g11020 458 Cytochrome b5-like heme/steroid binding domain + Oxidoreductase FAD/NAD(P)-binding + NADH:cytochrome b5 reductase (CBR) + Oxidoreductase, FAD-binding domain + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel + Cytochrome b5, heme-binding site Bcin01g11030 618 LDLR class B repeat + 3-hydroxyacyl-CoA dehydrogenase, C-terminal + 3-hydroxyacyl-CoA dehydrogenase, NAD binding + 6-phosphogluconate dehydrogenase C-terminal domain-like + Six-bladed beta-propeller, TolB-like + 6-phosphogluconate dehydrogenase, domain 2 + NAD(P)-binding domain Bcin01g11040 739 CAZy : GH78PCW pectin//SignalP-TM Bacterial alpha-L-rhamnosidase + Six-hairpin glycosidase-like + Galactose-binding domain-like Bcin01g11050 351 Six-bladed beta-propeller, TolB-like Bcin01g11060 387 Bcin01g11070 781 Bcin01g11080 380 Bcin01g11090 151 Bcin01g11100 166 SignalP-TM Bcin01g11110 444 Nicotinamide riboside kinase + P-loop containing nucleoside triphosphate hydrolase Bcin01g11120 316 Cyclin-like Bcin01g11130 370 Bcin01g11140 290 S-adenosyl-L-methionine-dependent methyltransferase Bcin01g11150 332 CAZy : CE8PCW pectin//SignalP-TM Pectinesterase, catalytic + Pectin lyase fold/virulence factor + Pectin lyase fold + Pectinesterase, Asp active site Bcin01g11160 412 CAZy : GH28PCW pectin//SignalP-noTM Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin01g11170 386 Protease//SignalP-noTM Peptidase M28 Bcin01g11180 244 Bcin01g11190 299 Bcin01g11200 521 Major facilitator superfamily + Major facilitator superfamily domain Bcin01g11210 158 Effector(V1) Bcin01g11220 294 CAZy : GH17FCW //SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Glycoside hydrolase, family 17 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin01g11230 267 Cytochrome c oxidase assembly protein COX14 Bcin01g11240 260 Protein of unknown function DUF2458 Bcin01g11250 415 Bcin01g11260 95 Effector(V2)|Effector(V1) Bcin01g11270 391 NADP-dependent oxidoreductase domain Bcin01g11280 320 Protein of unknown function DUF3425 Bcin01g11290 414 CAZy : GH76FCW //SignalP-noTM Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase Bcin01g11300 343 SignalP-noTM Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Bcin01g11310 596 Bcgod2, Glucose oxidase Bcin01g11320 302 Early secretome Bcin01g11330 565 SignalP-noTM "Bcgtb1, similar to yeast GTB1, Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p; involved in removal of two glucose residues from N-linked glycans during glycoprotein biogenesis in the ER; relocalizes from ER to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000002629]" Bcin01g11340 1292 Bcin01g11350 330 Protein of unknown function DUF602 + Zinc finger, RING/FYVE/PHD-type + Replication termination factor 2, RING-finger Bcin01g11360 2431 BcTOR, Target of rapamycin (Xiong et al., 2019) Bcin01g11370 269 DnaJ domain + DnaJ domain, conserved site Bcin01g11380 590 Major facilitator superfamily + Major facilitator superfamily domain Bcin01g11390 530 Protease Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin01g11400 335 Effector(V2) Bcin01g11410 211 Zn2/Cys6 transcription factor//Effector(V1) Zn(2)-C6 fungal-type DNA-binding domain Bcin01g11420 215 Bcgst22, Glutathione S-transferase Bcin01g11430 342 Ketopantoate reductase ApbA/PanE + 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + Ketopantoate reductase, N-terminal domain + Ketopantoate reductase, C-terminal domain + NAD(P)-binding domain Bcin01g11440 237 Tannase/feruloyl esterase Bcin01g11450 1430 SM cluster PKS5-NRPS7 (KE) Bcnrps7, Nonribosomal peptide synthetase Bcin01g11460 332 SM cluster PKS5-NRPS7 Bcin01g11470 194 SM cluster PKS5-NRPS7//Effector(V1) Calycin Bcin01g11480 1059 SM cluster PKS5-NRPS7 Cytochrome P450 + Oxidoreductase FAD/NAD(P)-binding + Cytochrome P450, E-class, group I + FAD-binding, type 1 + Flavodoxin/nitric oxide synthase + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel + Cytochrome P450, conserved site + NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 + Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase + Flavoprotein-like Bcin01g11490 371 SM cluster PKS5-NRPS7 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin01g11500 316 SM cluster PKS5-NRPS7//Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin01g11510 496 Zn2/Cys6 transcription factor//SM cluster PKS5-NRPS7 Zn(2)-C6 fungal-type DNA-binding domain Bcin01g11520 508 SM cluster PKS5-NRPS7 S-adenosyl-L-methionine-dependent methyltransferase Bcin01g11530 382 SM cluster PKS5-NRPS7 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin01g11540 306 SM cluster PKS5-NRPS7 HpcH/HpaI aldolase/citrate lyase domain + Pyruvate/Phosphoenolpyruvate kinase-like domain Bcin01g11550 4085 SM cluster PKS5-NRPS7 (KE) Bcpks5, Polyketide synthase (PKS-NRPS) Bcin01g11560 1386 Bcin02g00002 185 Effector(V2)|Effector(V1) Bcin02g00003 179 Effector(V2)|Effector(V1) Bcin02g00004 247 Bcin02g00005 1029 Bcin02g00006 428 Bcin02g00007 627 Bcin02g00008 1233 Bcin02g00009 354 Bcin02g00010 471 Bcin02g00011 1480 Bcin02g00012 118 Bcin02g00013 447 SM cluster MelA-like Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin02g00014 384 SM cluster MelA-like GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin02g00015 86 SM cluster MelA-like//Effector(V2)|Effector(V1) Bcin02g00016 931 SM cluster MelA-like (KE) AMP-dependent synthetase/ligase + Thioesterase + Acyl carrier protein-like + Polyketide synthase, thioesterase domain + Polyketide synthase, phosphopantetheine-binding domain + AMP-binding, conserved site + Alpha/Beta hydrolase fold Bcin02g00018 360 SignalP-noTM Intradiol ring-cleavage dioxygenase, core Bcin02g00020 591 Heterokaryon incompatibility Bcin02g00030 813 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin02g00040 514 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g00050 479 CAZy : GH88PCW pectin Six-hairpin glycosidase-like + Glycosyl hydrolase, family 88 + Six-hairpin glycosidase Bcin02g00060 480 CAZy : GH28PCW pectin Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin02g00070 410 SignalP-noTM Alginate lyase domain + Chondroitin AC/alginate lyase Bcin02g00080 537 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin02g00090 693 Bcin02g00100 288 Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin02g00110 529 "Bcgcd14, similar to yeast GCD14, Subunit of tRNA (1-methyladenosine) methyltransferase; required, along with Gcd10p, for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression [Source:SGD;Acc:S000003661]" Bcin02g00120 829 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding + Rossmann-like alpha/beta/alpha sandwich fold + Cysteine-tRNA ligase + Cysteinyl-tRNA synthetase/mycothiol ligase + tRNA synthetases class I, catalytic domain Bcin02g00130 850 Cys2His2 transcription factor + Fungal_trans Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin02g00140 413 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin02g00150 263 Effector(V2) Phospholipase/carboxylesterase/thioesterase + Alpha/Beta hydrolase fold Bcin02g00160 125 Protein of unknown function DUF3759 Bcin02g00170 625 Protease//Early secretome "Bcape1, similar to yeast APE1, Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway; protein increases in abundance and relative distribution to cytoplasmic foci increases upon DNA replication stress [Source:SGD;Acc:S000001586]" Bcin02g00180 520 SignalP-noTM Bcin02g00190 1765 yes BcJar1, Histone 3 Lysine 4 (H3K4) demethylase Bcin02g00200 424 "Bcslx1, similar to yeast SLX1, Endonuclease involved in DNA recombination and repair; subunit of a complex, with Slx4p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p [Source:SGD;Acc:S000000432]" Bcin02g00210 590 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin02g00220 597 FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin02g00230 292 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin02g00240 546 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin02g00250 326 UbiA prenyltransferase family Bcin02g00260 414 Bcin02g00270 140 Effector(V2)|Effector(V1) EthD domain + Dimeric alpha-beta barrel Bcin02g00280 577 SignalP-noTM//Early secretome FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin02g00290 124 Effector(V2)|Effector(V1) Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin02g00300 439 Mycolic acid cyclopropane synthase + S-adenosyl-L-methionine-dependent methyltransferase Bcin02g00310 227 Effector(V2) Bcgst7, Glutathione S-transferase Bcin02g00320 354 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + NAD(P)-binding domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Bcin02g00330 495 Bcin02g00340 377 Bcin02g00350 377 CAZy : GH16FCW //SignalP-noTM Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin02g00360 332 Carbon-nitrogen hydrolase Bcin02g00370 518 CAZy : GH76FCW Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase Bcin02g00380 125 Effector(V2)|Effector(V1) Conserved hypothetical protein CHP04076 Bcin02g00390 691 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin02g00400 578 NADP-dependent oxidoreductase domain Bcin02g00410 552 Amino acid/polyamine transporter I + Amino acid permease/ SLC12A domain Bcin02g00420 772 CAZy : GH3PCW/FCW Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Fibronectin type III-like domain Bcin02g00430 754 CAZy : GH71,CBM24,CBM24,CBM24,CBM24FCW //SignalP-noTM Glycoside hydrolase, family 71 Bcin02g00440 290 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin02g00450 138 Effector(V2)|Effector(V1) Bcin02g00460 531 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin02g00470 294 Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin02g00480 297 Bcin02g00490 166 Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like + Ubiquitin-conjugating enzyme, active site Bcin02g00500 1166 NACHT-NTPase and P-loop NTPases, N-terminal domain + Ankyrin repeat + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin02g00510 571 Bcin02g00520 404 CAZy : GT8 Alpha-mannosyltransferase + Nucleotide-diphospho-sugar transferases + Glucose N-acetyltransferase 1 Bcin02g00530 179 Effector(V2)|Effector(V1) Bcin02g00540 340 Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin02g00550 457 Bcin02g00560 209 Bcin02g00570 345 CAZy : GH18FCW Glycoside hydrolase, family 18, catalytic domain + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin02g00580 225 SignalP-noTM//Effector(V2)|Effector(V1) Bcin02g00590 277 Bcin02g00600 700 Ankyrin repeat + Ankyrin repeat-containing domain Bcin02g00610 1189 Bcin02g00620 569 Transporter Sugar/inositol transporter + General substrate transporter + Major facilitator superfamily domain Bcin02g00630 680 "Bcsen2, similar to yeast SEN2, Subunit of the tRNA splicing endonuclease; tRNA splicing endonuclease is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen2p contains the active site for tRNA 5' splice site cleavage and has similarity to Sen34p and to Archaeal tRNA splicing endonuclease [Source:SGD;Acc:S000004095]" Bcin02g00640 533 CAZy : GT21 Ceramide glucosyltransferase + Nucleotide-diphospho-sugar transferases Bcin02g00650 185 Bcin02g00660 397 "Bcsgt1, similar to yeast SGT1, Cochaperone protein; regulates activity of adenylyl cyclase Cyr1p; involved in kinetochore complex assembly; associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex; acts as a linker between Skp1p and HSP90 complexes; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005583]" Bcin02g00670 751 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid + Squalene cyclase + Squalene cyclase, C-terminal + Squalene cyclase, N-terminal Bcin02g00680 433 "Bcspo11, similar to yeast SPO11, Meiosis-specific protein that initiates meiotic recombination; initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction; required for homologous chromosome pairing and synaptonemal complex formation [Source:SGD;Acc:S000001014]" Bcin02g00690 726 Bcin02g00700 276 CAZy : GH128 //SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Glycoside hydrolase superfamily + Uncharacterised protein family, glycosyl hydrolase catalytic domain + Glycoside hydrolase, catalytic domain Bcin02g00710 1032 "Bcsyg1, similar to yeast SYG1, Plasma membrane protein of unknown function; truncation and overexpression suppresses lethality of G-alpha protein deficiency [Source:SGD;Acc:S000001309]" Bcin02g00720 445 Bcin02g00730 683 Bcin02g00740 456 Cation efflux protein + Cation efflux protein transmembrane domain + Cation efflux protein cytoplasmic domain Bcin02g00750 479 SET domain Bcin02g00760 276 Methyltransferase type 11 + S-adenosyl-L-methionine-dependent methyltransferase Bcin02g00770 764 Bcin02g00780 548 Platelet-activating factor acetylhydrolase + Platelet-activating factor acetylhydrolase, eucaryote + Alpha/Beta hydrolase fold Bcin02g00790 1251 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin02g00800 89 SignalP-noTM//Effector(V1) Bcpic4, Gene with maximal expression at Complete colonization Bcin02g00810 299 SM 0 Protein of unknown function DUF3328 Bcin02g00820 326 Bcin02g00830 739 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin02g00840 496 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g00850 1152 "Bcsla1, similar to yeast SLA1, Cytoskeletal protein binding protein; required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains [Source:SGD;Acc:S000000103]" Bcin02g00860 224 SignalP-noTM//Effector(V1) Bcin02g00870 268 Bcgst8, Glutathione S-transferase Bcin02g00880 498 WW domain Bcin02g00890 252 SignalP-noTM GPI-Mannosyltransferase II co-activator, Pga1 Bcin02g00900 450 Tubulin + Alpha tubulin + Tubulin/FtsZ, GTPase domain + Tubulin/FtsZ, C-terminal + Tubulin, conserved site + Tubulin/FtsZ, 2-layer sandwich domain + Tubulin, C-terminal Bcin02g00910 1329 "Bcede1, similar to yeast EDE1, Putative regulator of cytokinesis; also involved in endocytosis and has a network of interactions with other endocytic proteins; binds membranes in a ubiquitin-dependent manner; may also bind ubiquitinated membrane-associated proteins; interacts with Cmk2 and functions upstream of CMK2 in regulating non-apoptotic cell death [Source:SGD;Acc:S000000143]" Bcin02g00920 390 "Bcrfc3, similar to yeast RFC3, Subunit of heteropentameric Replication factor C (RF-C); which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005234]" Bcin02g00930 275 Bcin02g00940 114 Effector(V2) Bcin02g00950 400 Ubiquitin-conjugating enzyme E2-binding protein Bcin02g00960 427 Domain of unknown function DUF4243 Bcin02g00970 516 Bcin02g00980 384 Bcin02g00990 500 Ankyrin repeat + Asparaginase/glutaminase + Ankyrin repeat-containing domain + L-asparaginase, C-terminal domain + L-asparaginase, N-terminal Bcin02g01000 328 Nucleosome assembly protein (NAP) Bcin02g01010 680 Bcin02g01020 505 Protein of unknown function DUF1688 Bcin02g01030 921 "Bcswa2, similar to yeast SWA2, Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles [Source:SGD;Acc:S000002728]" Bcin02g01040 426 DnaJ domain + DnaJ domain, conserved site Bcin02g01050 369 Bcin02g01060 189 Effector(V2)|Effector(V1) "Bcynk1, similar to yeast YNK1, Nucleoside diphosphate kinase; catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001550]" Bcin02g01070 965 CAZy : GH31PCW hemicellulose "Bcrot2, similar to yeast ROT2, Glucosidase II catalytic subunit; required for normal cell wall synthesis; mutations in rot2 suppress tor2 mutations, and are synthetically lethal with rot1 mutations [Source:SGD;Acc:S000000433]" Bcin02g01080 222 Effector(V2)|Effector(V1) Large-conductance mechanosensitive channel Bcin02g01090 203 "Bcyar1, similar to yeast YAR1, Ankyrin-repeat containing, nucleocytoplasmic shuttling chaperone; prevents aggregation of Rps3p in the cytoplasm, associates with free Rps3p in the cytoplasm and delivers it to the 90S in the nucleus; required for 40S ribosomal subunit export, biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock [Source:SGD;Acc:S000006160]" Bcin02g01100 201 Bcin02g01110 132 Effector(V2)|Effector(V1) Bcin02g01120 173 Effector(V2)|Effector(V1) Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin02g01130 364 Bcin02g01140 93 Bcin02g01150 488 Bcin02g01160 706 "Bcrlf2, similar to yeast RLF2, Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1); chromatin assembly by CAF-1 is important for multiple processes including silencing at telomeres, mating type loci, and rDNA; maintenance of kinetochore structure; deactivation of the DNA damage checkpoint after DNA repair; chromatin dynamics during transcription; and repression of divergent noncoding transcription [Source:SGD;Acc:S000006222]" Bcin02g01170 381 Bcin02g01180 53 Effector(V1) Bcin02g01190 377 SignalP-noTM Bcin02g01200 179 Bcin02g01210 1273 BRCT domain Bcin02g01220 214 ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin02g01230 141 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin02g01240 110 Effector(V2) Polyketide cyclase SnoaL-like domain + NTF2-like domain Bcin02g01250 179 RNA ligase/cyclic nucleotide phosphodiesterase Bcin02g01260 513 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin02g01270 674 Transporter//Effector(V2)|Effector(V1) Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin02g01280 947 "Bcrad24, similar to yeast RAD24, Checkpoint protein; involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein [Source:SGD;Acc:S000000975]" Bcin02g01290 820 Pumilio RNA-binding repeat + Armadillo-like helical + Armadillo-type fold + Pumilio homology domain Bcin02g01300 109 Effector(V1) "Bcrsm27, similar to yeast RSM27, Mitochondrial ribosomal protein of the small subunit [Source:SGD;Acc:S000003447]" Bcin02g01310 425 "Bcrnt1, similar to yeast RNT1, Nuclear dsRNA-specific ribonuclease (RNase III); involved in rDNA transcription, rRNA processing and U2 snRNA 3' end formation by cleavage of a stem-loop structure at the 3' end of U2 snRNA; involved in polyadenylation-independent transcription termination; involved in the cell wall stress response, regulating the degradation of cell wall integrity and morphogenesis checkpoint genes [Source:SGD;Acc:S000004852]" Bcin02g01320 301 Acyl-CoA-binding protein, ACBP + FERM/acyl-CoA-binding protein, 3-helical bundle Bcin02g01330 137 Effector(V2)|Effector(V1) Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin02g01340 1185 Bcin02g01350 353 Protease WLM + Ubiquitin-related domain Bcin02g01360 213 "Bcerd2, similar to yeast ERD2, HDEL receptor; an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins [Source:SGD;Acc:S000000136]" Bcin02g01370 742 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site + 2Fe-2S ferredoxin-type domain + Molybdopterin oxidoreductase + Molybdopterin oxidoreductase, 4Fe-4S domain + NADH:ubiquinone oxidoreductase, subunit G + Beta-grasp domain + NADH-quinone oxidoreductase, chain G, C-terminal + NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding Bcin02g01380 1326 Bcin02g01390 629 "Bcnrp1, similar to yeast NRP1, Putative RNA binding protein of unknown function; localizes to stress granules induced by glucose deprivation; predicted to be involved in ribosome biogenesis [Source:SGD;Acc:S000002326]" Bcin02g01400 154 SignalP-noTM Bcin02g01410 118 Effector(V1) Bcin02g01420 500 CAZy : GH13Energy //SignalP-noTM//Early secretome Glycosyl hydrolase, family 13, catalytic domain + Glycosyl hydrolase, family 13, all-beta + Glycoside hydrolase, catalytic domain + Alpha-amylase, domain of unknown function DUF1966, C-terminal + Glycoside hydrolase superfamily Bcin02g01430 231 Effector(V2) "Bcspc3, similar to yeast SPC3, Subunit of signal peptidase complex; complex catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC22/23; other members of the complex are Spc1p, Spc2p, and Sec11p [Source:SGD;Acc:S000004056]" Bcin02g01440 94 SignalP-TM//Effector(V1) Proteolipid membrane potential modulator Bcin02g01450 580 Carboxyl transferase + Acetyl-coenzyme A carboxyltransferase, N-terminal + Acetyl-coenzyme A carboxyltransferase, C-terminal + ClpP/crotonase-like domain Bcin02g01460 675 "Bchfa1, similar to yeast HFA1, Mitochondrial acetyl-coenzyme A carboxylase; catalyzes production of malonyl-CoA in mitochondrial fatty acid biosynthesis; relocalizes from mitochondrion to cytoplasm upon DNA replication stress; HFA1 has a paralog, ACC1, that arose from the whole genome duplication [Source:SGD;Acc:S000004820]" Bcin02g01470 1288 Ankyrin repeat + Ankyrin repeat-containing domain + Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB Bcin02g01480 987 Heterokaryon incompatibility Bcin02g01490 246 Bcin02g01500 308 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g01510 305 WW domain Bcin02g01520 653 Bcin02g01530 176 Effector(V1) Bcin02g01540 568 yes Signaling pathway BccnA, Catalytic subunit of calcineurin Bcin02g01550 220 Bzip transcription factor Basic-leucine zipper domain Bcin02g01560 278 Effector(V1) Bcin02g01570 579 Transporter Amino acid/polyamine transporter I Bcin02g01580 572 CoA-transferase family III + CoA-transferase family III domain Bcin02g01590 630 Protein of unknown function DUF1446 Bcin02g01600 654 Heterokaryon incompatibility Bcin02g01610 428 yes Bcnde3, External NADH dehydrogenase 3 Bcin02g01620 243 Bcin02g01630 185 GNAT domain + Acyl-CoA N-acyltransferase Bcin02g01640 454 CAZy : GH27PCW hemicellulose//SignalP-noTM Glycoside hydrolase, clan GH-D + Glycoside hydrolase, family 27 + Glycosyl hydrolase, family 13, all-beta + Aldolase-type TIM barrel + Glycoside hydrolase superfamily Bcin02g01650 527 Transporter//SM cluster PKS2 Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin02g01660 464 Transporter//SM cluster PKS2 Amino acid transporter, transmembrane domain Bcin02g01670 124 SM cluster PKS2//Effector(V1) Bcin02g01680 3183 SM cluster PKS2 (KE) Bcpks2, Polyketide synthase Bcin02g01690 467 SignalP-noTM Lipase, secreted + Putative lysophospholipase + Alpha/Beta hydrolase fold Bcin02g01700 372 Bcin02g01710 553 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g01720 863 Phospholipase D/Transphosphatidylase + Phospholipase D family + Phospholipase D-like domain Bcin02g01730 345 GroES (chaperonin 10)-like + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin02g01740 263 PQ-loop repeat Bcin02g01750 385 DNA topoisomerase, type IA + Zinc finger, GRF-type Bcin02g01760 1351 Protease "Bcade6, similar to yeast ADE6, Formylglycinamidine-ribonucleotide (FGAM)-synthetase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway [Source:SGD;Acc:S000003293]" Bcin02g01770 357 Opine dehydrogenase + 6-phosphogluconate dehydrogenase C-terminal domain-like + Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal + 6-phosphogluconate dehydrogenase, domain 2 + NAD(P)-binding domain Bcin02g01780 273 Methyltransferase type 11 + S-adenosyl-L-methionine-dependent methyltransferase Bcin02g01790 456 BctubB, Alpha-tubulin B Bcin02g01800 1044 Cys2His2 transcription factor Arsenite-resistance protein 2 + Zinc finger, C2H2 + Protein of unknown function DUF3546 + Domain of unknown function DUF4187 Bcin02g01810 201 TspO/MBR-related protein Bcin02g01820 335 Transporter "Bcort1, similar to yeast ORT1, Ornithine transporter of the mitochondrial inner membrane; exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome [Source:SGD;Acc:S000005656]" Bcin02g01830 119 "Bccgr1, similar to yeast CGR1, Protein involved in nucleolar integrity and processing of pre-rRNA; has a role in processing rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress; relocalizes from nucleus to nucleolus upon DNA replication stress [Source:SGD;Acc:S000002997]" Bcin02g01840 350 Bcin02g01850 944 Phox homologous domain + Domain of unknown function DUF3818, PX-associated + PX-associated domain Bcin02g01860 268 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site + Cytochrome P450, E-class, group IV Bcin02g01870 432 NADH:flavin oxidoreductase/NADH oxidase, N-terminal + Aldolase-type TIM barrel Bcin02g01880 314 NmrA-like domain + NAD(P)-binding domain Bcin02g01890 179 Effector(V1) RmlC-like cupin domain + RmlC-like jelly roll fold + ChrR-like cupin domain Bcin02g01900 850 Zn2/Cys6 + fungal trans transcription factor Forkhead-associated (FHA) domain + Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin02g01910 632 Methyltransferase domain Bcin02g01920 532 "Bccct4, similar to yeast CCT4, Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo [Source:SGD;Acc:S000002302]" Bcin02g01930 439 "Bcrpt1, similar to yeast RPT1, ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and Ubr1p; mutant has aneuploidy tolerance [Source:SGD;Acc:S000001628]" Bcin02g01940 524 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin02g01950 268 Bcin02g01960 330 CAZy : GH45,CBM1PCW cellulose//SignalP-noTM//Early secretome Cellulose-binding domain, fungal + Glycoside hydrolase, family 45 + RlpA-like double-psi beta-barrel domain Bcin02g01970 196 Effector(V2)|Effector(V1) Enamine/imine deaminase YjgF-like + YjgF/Yer057p/UK114 family + Endoribonuclease L-PSP/chorismate mutase-like + YjgF-like protein, conserved site Bcin02g01980 769 yes CAZy : GT39 Bcpmt4, Protein o-mannosyltransferase, subfamily PMT4 Bcin02g01990 221 Effector(V2) NAD(P)-binding domain Bcin02g02000 323 CAZy : GH43PCW hemicellulose or pectin Glycoside hydrolase, family 43 + Glycosyl hydrolase, five-bladed beta-propellor domain Bcin02g02010 936 Protease Protein of unknown function DUF544 + MINDY deubiquitinase domain Bcin02g02020 594 "Bcgcd10, similar to yeast GCD10, Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p; required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression [Source:SGD;Acc:S000005006]" Bcin02g02030 192 Effector(V1) "Bcarc18, similar to yeast ARC18, Subunit of the ARP2/3 complex; ARP2/3 is required for the motility and integrity of cortical actin patches [Source:SGD;Acc:S000004362]" Bcin02g02040 269 CAZy : AA9 //SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Glycoside hydrolase, family 61 Bcin02g02050 205 Effector(V2)|Effector(V1) Isochorismatase-like Bcin02g02060 489 Leucine-rich repeat domain, L domain-like Bcin02g02070 244 Bcin02g02080 449 Bcin02g02090 956 Methyltransferase type 11 + S-adenosyl-L-methionine-dependent methyltransferase Bcin02g02100 505 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin02g02110 252 Effector(V1) "Bcrpe1, similar to yeast RPE1, D-ribulose-5-phosphate 3-epimerase; catalyzes a reaction in the non-oxidative part of the pentose-phosphate pathway; mutants are sensitive to oxidative stress [Source:SGD;Acc:S000003657]" Bcin02g02120 379 SignalP-noTM Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin02g02130 249 Bcin02g02140 198 Effector(V2)|Effector(V1) Bcin02g02150 398 Aminotransferase class V domain + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin02g02160 683 "Bctpa1, similar to yeast TPA1, Poly(rA)-binding protein; involved in translation termination efficiency, mRNA poly(A) tail length and mRNA stability; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; similar to human prolyl 4-hydroxylase OGFOD1; binds Fe(III) and 2-oxoglutarate [Source:SGD;Acc:S000000851]" Bcin02g02170 536 Cytochrome P450 + Cytochrome P450, E-class, group II + Cytochrome P450, E-class, CYP52 + Cytochrome P450, conserved site Bcin02g02180 354 Bcin02g02190 510 Protease Lipase, GDXG, active site + Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold + Lipase, GDXG, putative serine active site Bcin02g02200 1185 Forkhead-associated (FHA) domain + Protein kinase domain + Serine/threonine-protein kinase, active site + SMAD/FHA domain + Protein kinase-like domain + Protein kinase, ATP binding site + Calcium/calmodulin-dependent/calcium-dependent protein kinase Bcin02g02210 241 SignalP-noTM Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Bcin02g02220 748 Bcin02g02230 1076 Bcin02g02240 753 CAZy : GT66 "Bcstt3, similar to yeast STT3, Subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes asparagine-linked glycosylation of newly synthesized proteins; forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis [Source:SGD;Acc:S000002990]" Bcin02g02250 93 Effector(V2)|Effector(V1) ATPase, F0 complex, subunit E, mitochondrial Bcin02g02260 704 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin02g02270 851 Protein of unknown function DUF726 + Alpha/Beta hydrolase fold Bcin02g02280 688 Protease Peptidase C19, ubiquitin carboxyl-terminal hydrolase + Ubiquitin specific protease domain Bcin02g02290 268 "Bctrm9, similar to yeast TRM9, tRNA methyltransferase; catalyzes modification of wobble bases in tRNA anticodons to 2, 5-methoxycarbonylmethyluridine and 5-methoxycarbonylmethyl-2-thiouridine; may act as part of a complex with Trm112p; deletion mutation increases translational infidelity, including amino acid misincorporation and -1 frameshifting, and also confers resistance to zymocin; null mutant displays activation of stress responses [Source:SGD;Acc:S000004476]" Bcin02g02300 381 SANT/Myb domain + Homeodomain-like + Myb-like domain + Myb domain Bcin02g02310 247 "Bcalf1, similar to yeast ALF1, Alpha-tubulin folding protein; similar to mammalian cofactor B; Alf1p-GFP localizes to cytoplasmic microtubules; required for the folding of alpha-tubulin and may play an additional role in microtubule maintenance [Source:SGD;Acc:S000005092]" Bcin02g02320 400 Oxidoreductase, N-terminal + NAD(P)-binding domain Bcin02g02330 520 SignalP-noTM Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin02g02340 120 SignalP-noTM//Effector(V2)|Effector(V1) Bcin02g02350 263 "Bcmrp7, similar to yeast MRP7, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000004950]" Bcin02g02360 1288 Protease "Bccyk3, similar to yeast CYK3, SH3-domain protein located in the bud neck and cytokinetic actin ring; relocalizes from bud neck to nucleus upon DNA replication stress; activates the chitin synthase activity of Chs2p during cytokinesis; suppressor of growth and cytokinesis defects of chs2 phospho-mutants [Source:SGD;Acc:S000002275]" Bcin02g02370 623 Protein kinase domain + Protein kinase-like domain + Protein kinase, ATP binding site Bcin02g02380 2619 SM cluster NRPS4 (KE) Bcnrps4, Nonribosomal peptide synthetase Bcin02g02390 557 SM cluster NRPS4 Tetracycline resistance protein, TetA/multidrug resistance protein MdtG + Major facilitator superfamily + Major facilitator superfamily domain Bcin02g02400 485 "Bcrad57, similar to yeast RAD57, Protein that stimulates strand exchange; stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad55p [Source:SGD;Acc:S000002411]" Bcin02g02410 409 CAZy : GH128 //SignalP-noTM//Early secretome Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Uncharacterised protein family, glycosyl hydrolase catalytic domain Bcin02g02420 856 Acyltransferase ChoActase/COT/CPT Bcin02g02430 524 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin02g02440 579 SignalP-noTM Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin02g02450 234 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin02g02460 300 NmrA-like domain + NAD(P)-binding domain Bcin02g02470 674 VHS + CID domain + ENTH/VHS + Subunit of cleavage factor IA Pcf11 Bcin02g02480 102 SignalP-noTM//Effector(V2)|Effector(V1) Proteinase inhibitor, propeptide + Peptidase S8 propeptide/proteinase inhibitor I9 Bcin02g02490 744 Hook-related protein family Bcin02g02500 765 "Bcmak10, similar to yeast MAK10, Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus; expression is glucose-repressible [Source:SGD;Acc:S000000779]" Bcin02g02510 74 Effector(V1) ATPase, F1 complex, epsilon subunit, mitochondrial Bcin02g02520 461 Protease "Bcqcr2, similar to yeast QCR2, Subunit 2 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; phosphorylated; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme [Source:SGD;Acc:S000006395]" Bcin02g02530 666 "Bcrpc82, similar to yeast RPC82, RNA polymerase III subunit C82 [Source:SGD;Acc:S000006394]" Bcin02g02540 304 Transporter "Bcggc1, similar to yeast GGC1, Mitochondrial GTP/GDP transporter; essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family [Source:SGD;Acc:S000002357]" Bcin02g02550 64 Effector(V2)|Effector(V1) Non-classical export protein 1 Bcin02g02560 594 Bcin02g02570 123 yes Bcatg8, Autophagy gene Bcin02g02580 424 Bccpd2, Coproporphyrinogen III oxidase Bcin02g02590 355 Bcin02g02600 355 Protease "Bcrpn8, similar to yeast RPN8, Essential non-ATPase regulatory subunit of the 26S proteasome; has similarity to the human p40 proteasomal subunit and to another S. cerevisiae regulatory subunit, Rpn11p [Source:SGD;Acc:S000005787]" Bcin02g02610 275 Effector(V1) "Bcadk1, similar to yeast ADK1, Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002634]" Bcin02g02620 206 Effector(V1) Bcin02g02630 812 "Bcdnm1, similar to yeast DNM1, Dynamin-related GTPase involved in mitochondrial organization; required for mitochondrial fission and morphology; assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis and regulating peroxisome abundance [Source:SGD;Acc:S000003924]" Bcin02g02640 842 "Bcctf4, similar to yeast CTF4, Chromatin-associated protein; required for sister chromatid cohesion; interacts with DNA polymerase alpha (Pol1p) and may link DNA synthesis to sister chromatid cohesion [Source:SGD;Acc:S000006339]" Bcin02g02650 397 Effector(V2)|Effector(V1) WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat + PLAA/Doa1/Lub1 Bcin02g02660 1200 Bcin02g02670 312 yes SM cluster Bop1//Signaling pathway Bop1, G protein-coupled receptor (GPCR) : Microbial opsin, opsin-like1, potential green light sensor Bcin02g02680 394 GATS-like ACT domain Bcin02g02690 571 CID domain + RNA polymerase II-binding domain + ENTH/VHS Bcin02g02700 121 Effector(V1) Protein of unknown function DUF4748 Bcin02g02710 1181 Inositol polyphosphate-related phosphatase + Endonuclease/exonuclease/phosphatase + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin02g02720 230 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin02g02730 706 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin02g02740 317 Transporter "Bcyhm2, similar to yeast YHM2, Citrate and oxoglutarate carrier protein; exports citrate from and imports oxoglutarate into the mitochondrion, causing net export of NADPH reducing equivalents; also associates with mt nucleoids and has a role in replication and segregation of the mt genome [Source:SGD;Acc:S000004854]" Bcin02g02750 473 Citrate synthase-like + Citrate synthase, eukaryotic + Citrate synthase-like, large alpha subdomain + Citrate synthase active site Bcin02g02760 693 "Bcnrd1, similar to yeast NRD1, RNA-binding subunit of Nrd1 complex; complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; interacts with CTD of RNA pol II large subunit Rpo21p at phosphorylated Ser5 to direct transcription termination of non-polyadenylated transcripts; H3K4 trimethylation of transcribed regions by Set1p enhances recruitment of Nrd1p to those sites; role in regulation of mitochondrial abundance and cell size [Source:SGD;Acc:S000005195]" Bcin02g02770 168 Bcin02g02780 615 yes SignalP-noTM "Bclcc13, Laccase/ Multicopper oxidase ; BcFET1, ferroxidase" Bcin02g02790 401 yes BcFTR1, membrane-bound iron permease Bcin02g02800 473 Conserved oligomeric Golgi complex subunit 8 Bcin02g02810 460 Protease Amidohydrolase 1 + Metal-dependent hydrolase Bcin02g02820 363 TRAM/LAG1/CLN8 homology domain Bcin02g02830 138 Effector(V2)|Effector(V1) Uncharacterised protein family Cys-rich Bcin02g02840 596 yes Signaling pathway Bcptc6, Type 2C Ser/Thr phosphatase (PP2C) Bcin02g02850 330 Protein kinase-like domain + Fructosamine/Ketosamine-3-kinase Bcin02g02860 64 Effector(V2)|Effector(V1) P-loop containing nucleoside triphosphate hydrolase Bcin02g02870 659 "Bcmif2, similar to yeast MIF2, Protein required for structural integrity of elongating spindles; localizes to the kinetochore; interacts with histones H2A, H2B, and H4; phosphorylated by Ipl1p; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-C and fission yeast cnp3 [Source:SGD;Acc:S000001572]" Bcin02g02880 348 "Bcrnh201, similar to yeast RNH201, Ribonuclease H2 catalytic subunit; removes RNA primers during Okazaki fragment synthesis and errant ribonucleotides misincorporated during DNA replication; role in ribonucleotide excision repair; homolog of RNAse HI; related to human AGS4 which causes Aicardi-Goutieres syndrome [Source:SGD;Acc:S000005016]" Bcin02g02890 1171 "Bcnic96, similar to yeast NIC96, Linker nucleoporin component of the nuclear pore complex (NPC); also part of the NPC nuclear basket; contributes to nucleocytoplasmic transport and NPC biogenesis; forms stable associations with three FG-nucleoporins (Nsp1p, Nup57p, and Nup49p) [Source:SGD;Acc:S000001898]" Bcin02g02900 563 Effector(V1) Protein of unknown function DUF3425 Bcin02g02910 614 Carbohydrate kinase, FGGY-related + Carbohydrate kinase, FGGY, N-terminal + Carbohydrate kinase, FGGY, C-terminal Bcin02g02920 389 "Bcrpt6, similar to yeast RPT6, ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003016]" Bcin02g02930 1157 Transporter "Bcvnx1, similar to yeast VNX1, Calcium/H+ antiporter localized to the endoplasmic reticulum membrane; member of the calcium exchanger (CAX) family; potential Cdc28p substrate [Source:SGD;Acc:S000005265]" Bcin02g02940 340 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin02g02950 589 F-box domain Bcin02g02960 583 Heat shock factor (HSF)-type, DNA-binding + Winged helix-turn-helix DNA-binding domain + Heat shock transcription factor family Bcin02g02970 495 WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin02g02980 107 Dimeric alpha-beta barrel Bcin02g02990 1274 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin02g03000 542 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g03010 327 Nitrilase/cyanide hydratase, conserved site + Carbon-nitrogen hydrolase Bcin02g03020 682 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin02g03030 361 Haem-containing dehydratase Bcin02g03040 675 Adenosine/AMP deaminase domain + Metal-dependent hydrolase Bcin02g03050 462 Major facilitator superfamily + Major facilitator superfamily domain Bcin02g03060 1285 BcppoA80, Fatty acid oxygenase Bcin02g03070 492 Acyltransferase 3 Bcin02g03080 189 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit + Succinate dehydrogenase, cytochrome b556 subunit + Succinate dehydrogenase, cytochrome b subunit, conserved site Bcin02g03090 602 SignalP-noTM//Early secretome Glycoside hydrolase, family 1 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Glycosyl hydrolases family 1, N-terminal conserved site Bcin02g03100 469 tRNA-guanine(15) transglycosylase-like Bcin02g03110 647 LCCL domain Bcin02g03120 117 Bcin02g03130 175 Bcin02g03140 422 SignalP-TM RTA-like protein Bcin02g03150 563 yes Bcrtt109, lysine acetyltransferase Bcin02g03160 264 Ribonuclease III domain Bcin02g03170 450 Bcin02g03180 534 "Bcspe2, similar to yeast SPE2, S-adenosylmethionine decarboxylase; required for the biosynthesis of spermidine and spermine; cells lacking Spe2p require spermine or spermidine for growth in the presence of oxygen but not when grown anaerobically [Source:SGD;Acc:S000005412]" Bcin02g03190 914 Gamma-tubulin complex component protein Bcin02g03200 394 CAZy : GT15 "Bcktr4, similar to yeast KTR4, Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family of type II membrane proteins with a short cytoplasmic N-terminus, a membrane-spanning region and a highly conserved catalytic lumenal domain [Source:SGD;Acc:S000000403]" Bcin02g03210 413 Protease Beta-lactamase-related + Beta-lactamase/transpeptidase-like Bcin02g03220 383 yes Bcaqp5, Aquaporin Bcin02g03230 84 Bcin02g03240 938 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin02g03250 356 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin02g03260 378 Protease Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin02g03270 623 Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin02g03280 309 "Bccfd1, similar to yeast CFD1, Highly conserved iron-sulfur cluster binding protein; localized in the cytoplasm; forms a complex with Nbp35p that is involved in iron-sulfur protein assembly in the cytosol [Source:SGD;Acc:S000001265]" Bcin02g03290 1004 Bcin02g03300 3858 "Bctra1, similar to yeast TRA1, Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation [Source:SGD;Acc:S000001141]" Bcin02g03310 349 Nicotianamine synthase + S-adenosyl-L-methionine-dependent methyltransferase Bcin02g03320 345 CCAAT transcription factor "Bchap2, similar to yeast HAP2, Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; complex is heme-activated and glucose-repressed; complex is a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding [Source:SGD;Acc:S000003206]" Bcin02g03330 461 Voltage-dependent anion channel Bcin02g03340 419 "Bcrna1, similar to yeast RNA1, GTPase activating protein (GAP) for Gsp1p; involved in nuclear transport [Source:SGD;Acc:S000004848]" Bcin02g03350 95 Effector(V2)|Effector(V1) Bccox17, COX copper chaperone Bcin02g03360 852 "Bcsec10, similar to yeast SEC10, Essential 100kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion [Source:SGD;Acc:S000004156]" Bcin02g03370 345 "Bcnus1, similar to yeast NUS1, Putative prenyltransferase; required for cell viability; proposed to be involved in protein trafficking because tet-repressible mutant shows accumulation of hypoglycosylated forms of CPY [Source:SGD;Acc:S000002352]" Bcin02g03380 346 Oxoglutarate/iron-dependent dioxygenase + Alpha-ketoglutarate-dependent dioxygenase AlkB-like Bcin02g03390 491 "Bctrm5, similar to yeast TRM5, tRNA(m(1)G37)methyltransferase; methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting; highly conserved across Archaea, Bacteria, and Eukarya [Source:SGD;Acc:S000001112]" Bcin02g03400 570 Protein of unknown function DUF1752, fungi Bcin02g03410 1001 "Bcpso2, similar to yeast PSO2, Nuclease required for DNA single- and double-strand break repair; acts at a post-incision step in repair of breaks that result from interstrand cross-links produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000004745]" Bcin02g03420 98 Effector(V2)|Effector(V1) "Bclsm2, similar to yeast LSM2, Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000000122]" Bcin02g03430 399 SignalP-noTM Nucleotide exchange factor Sil1, fungi Bcin02g03440 149 Chromo domain-like + Chromo domain Bcin02g03450 180 Effector(V2)|Effector(V1) Bcin02g03460 196 "Bcrpc25, similar to yeast RPC25, RNA polymerase III subunit C25; required for transcription initiation; forms a heterodimer with Rpc17p; paralog of Rpb7p [Source:SGD;Acc:S000001627]" Bcin02g03470 642 Zinc finger, CCCH-type Bcin02g03480 322 Protease Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin02g03490 417 "Bccys3, similar to yeast CYS3, Cystathionine gamma-lyase; catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000010]" Bcin02g03500 445 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin02g03510 144 Effector(V1) Bcin02g03520 340 Chromatin SPT2 Bcin02g03530 111 Early secretome Ribosomal protein L12 family Bcin02g03540 153 "Bcrps15, similar to yeast RPS15, Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15 and bacterial S19 [Source:SGD;Acc:S000005400]" Bcin02g03550 1294 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB + Alpha/Beta hydrolase fold Bcin02g03560 662 Transporter General substrate transporter + Major facilitator superfamily domain Bcin02g03570 353 "Bchpm1, similar to yeast HPM1, AdoMet-dependent methyltransferase; involved in a novel 3-methylhistidine modification of ribosomal protein Rpl3p; seven beta-strand MTase family member; null mutant exhibits a weak vacuolar protein sorting defect and caspofungin resistance [Source:SGD;Acc:S000001372]" Bcin02g03580 614 "Bcnop12, similar to yeast NOP12, Nucleolar protein involved in pre-25S rRNA processing; also involved in biogenesis of large 60S ribosomal subunit; contains an RNA recognition motif (RRM); binds to Ebp2; similar to Nop13p and Nsr1p [Source:SGD;Acc:S000005401]" Bcin02g03590 712 "Bcdep1, similar to yeast DEP1, Component of the Rpd3L histone deacetylase complex; required for diauxic shift-induced histone H2B deposition onto rDNA genes; transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes, as well as maintenance of telomeres, mating efficiency, and sporulation [Source:SGD;Acc:S000000011]" Bcin02g03600 72 Effector(V2)|Effector(V1) Coiled-coil domain-containing protein 56 Bcin02g03610 726 "Bcpta1, similar to yeast PTA1, Subunit of holo-CPF; holo-CPF is a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII [Source:SGD;Acc:S000000041]" Bcin02g03620 826 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin02g03630 1424 Transporter "Bcpdr11, similar to yeast PDR11, ATP-binding cassette (ABC) transporter; multidrug transporter involved in multiple drug resistance; mediates sterol uptake when sterol biosynthesis is compromised; regulated by Pdr1p; required for anaerobic growth; PDR11 has a paralog, AUS1, that arose from the whole genome duplication [Source:SGD;Acc:S000001275]" Bcin02g03640 420 Bcin02g03650 1015 Bcin02g03660 331 ATP-dependent (S)-NAD(P)H-hydrate dehydratase + Carbohydrate kinase, predicted, conserved site + Ribokinase-like Bcin02g03670 270 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin02g03680 134 Bcin02g03690 107 Effector(V2)|Effector(V1) Bcin02g03700 271 Bcin02g03710 293 Bcin02g03720 144 Effector(V1) Bcin02g03730 282 Bcin02g03740 305 Bcin02g03750 340 Bcin02g03760 474 Bcin02g03770 725 Protease Partial AB-hydrolase lipase domain + Alpha/Beta hydrolase fold Bcin02g03780 1390 "Bcpex6, similar to yeast PEX6, AAA-peroxin; heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol [Source:SGD;Acc:S000005273]" Bcin02g03790 455 Aromatic amino acid beta-eliminating lyase/threonine aldolase + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase + Threonine aldolase Bcin02g03800 330 TAFII28-like protein + Histone-fold Bcin02g03810 303 "Bcfol2, similar to yeast FOL2, GTP-cyclohydrolase I; catalyzes the first step in the folic acid biosynthetic pathway [Source:SGD;Acc:S000003499]" Bcin02g03820 242 Effector(V2)|Effector(V1) "Bccdc8, similar to yeast CDC8, Thymidylate and uridylate kinase; functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p [Source:SGD;Acc:S000003818]" Bcin02g03830 472 "Bctaf6, similar to yeast TAF6, Subunit (60 kDa) of TFIID and SAGA complexes; involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003080]" Bcin02g03840 669 SignalP-noTM Bcin02g03850 738 Bcin02g03860 709 Protease Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin02g03870 524 Domain of unknown function DUF1996 Bcin02g03880 399 ATP-dependent RNA helicase DEAD-box, conserved site + Helicase, C-terminal + DEAD/DEAH box helicase domain + Helicase superfamily 1/2, ATP-binding domain + RNA helicase, DEAD-box type, Q motif + P-loop containing nucleoside triphosphate hydrolase Bcin02g03890 497 Cys2His2 transcription factor "Bcprp9, similar to yeast PRP9, Subunit of the SF3a splicing factor complex; required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex [Source:SGD;Acc:S000002188]" Bcin02g03900 839 SET domain Bcin02g03910 492 Aldehyde dehydrogenase domain + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain + Aldehyde dehydrogenase, C-terminal Bcin02g03920 460 Bcin02g03930 471 "Bcoxa1, similar to yeast OXA1, Mitochondrial inner membrane insertase; mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane; also has a role in insertion of carrier proteins into the inner membrane; acts as a voltage-gated ion channel, activated by substrate peptides; interacts with mitochondrial ribosomes; conserved from bacteria to animals [Source:SGD;Acc:S000000956]" Bcin02g03940 128 Outer membrane protein, MIM1/TOM13, mitochondrial Bcin02g03950 419 "Bcshp1, similar to yeast SHP1, UBX (ubiquitin regulatory X) domain-containing protein; regulates Glc7p phosphatase activity; shp1 mutants are impaired in growth and mitotic progression; functions in growth and mitotic progression require Cdc48p binding; mitotic phenotype is caused by reduced Glc7p activity; interacts with ubiquitylated proteins, required for degradation of a ubiquitylated model substrate [Source:SGD;Acc:S000000154]" Bcin02g03960 1028 EF-hand domain + Mechanosensitive ion channel MscS + Like-Sm (LSM) domain + EF-hand domain pair + Mechanosensitive ion channel MscS-like, plants/fungi Bcin02g03970 570 NTF2-like domain Bcin02g03980 417 Proteasome component (PCI) domain + Winged helix-turn-helix DNA-binding domain Bcin02g03990 218 SGNH hydrolase-type esterase domain Bcin02g04000 839 "Bcmps1, similar to yeast MPS1, Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]" Bcin02g04010 257 "Bcjac1, similar to yeast JAC1, Specialized J-protein that functions in Fe-S cluster biogenesis; functions with Hsp70 in Fe-S cluster biogenesis in mitochondria; involved in iron metabolism; contains a J domain typical to J-type chaperones; localizes to the mitochondrial matrix [Source:SGD;Acc:S000002986]" Bcin02g04020 469 CAZy : GT34 "Bcmnn10, similar to yeast MNN10, Subunit of a Golgi mannosyltransferase complex; complex mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family; other members of the complex are Anp1p, Mnn9p, Mnn11p, and Hoc1p [Source:SGD;Acc:S000002653]" Bcin02g04030 423 SignalP-noTM Apple-like Bcin02g04040 355 SignalP-noTM//Effector(V2)|Effector(V1) Bcin02g04050 235 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin02g04060 1235 Bcin02g04070 211 Effector(V2)|Effector(V1) Bcin02g04080 514 "Bcprp4, similar to yeast PRP4, Splicing factor; component of the U4/U6-U5 snRNP complex [Source:SGD;Acc:S000006382]" Bcin02g04090 322 CAZy : GH16FCW //SignalP-noTM Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin02g04100 362 CAZy : GT17 Glycosyl transferase, family 17 Bcin02g04110 413 "Bcptc7, similar to yeast PTC7, Type 2C serine/threonine protein phosphatase (PP2C); alternatively spliced to create two mRNA isoforms; protein from spliced form localizes to the mitochondria while the one from the unspliced form is localized to the nuclear envelope; activates coenzyme Q6 biosynthesis by dephosphorylation of demethoxy-Q6 hydroxylase Coq7p [Source:SGD;Acc:S000001118]" Bcin02g04120 364 "Bctfg2, similar to yeast TFG2, TFIIF (Transcription Factor II) middle subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP30 [Source:SGD;Acc:S000003237]" Bcin02g04130 464 Zinc finger, CCCH-type Bcin02g04140 615 Bzip transcription factor Basic-leucine zipper domain Bcin02g04150 389 Sel1-like + Tetratricopeptide-like helical domain Bcin02g04160 544 CCAAT transcription factor "Bcnoc4, similar to yeast NOC4, Nucleolar protein; forms a complex with Nop14p that mediates maturation and nuclear export of 40S ribosomal subunits; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006348]" Bcin02g04170 244 "Bcatp4, similar to yeast ATP4, Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase; ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; contributes to the oligomerization of the complex, which in turn determines the shape of inner membrane cristae; phosphorylated [Source:SGD;Acc:S000005999]" Bcin02g04180 367 Effector(V1) Alpha/Beta hydrolase fold Bcin02g04190 261 "Bcnsa2, similar to yeast NSA2, Protein constituent of 66S pre-ribosomal particles; contributes to processing of the 27S pre-rRNA [Source:SGD;Acc:S000000928]" Bcin02g04200 212 "Bcmrpl49, similar to yeast MRPL49, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000003632]" Bcin02g04210 403 Bcin02g04220 373 Ribosomal protein L4/L1e + Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site + Ribosomal protein L4 domain + 60S ribosomal protein L4, C-terminal domain Bcin02g04230 473 Bcin02g04240 343 ELO family Bcin02g04250 165 Effector(V2)|Effector(V1) "Bccox6, similar to yeast COX6, Subunit VI of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain; expression is regulated by oxygen levels [Source:SGD;Acc:S000001093]" Bcin02g04260 1687 Protease "Bculp2, similar to yeast ULP2, Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins; plays a role in chromosome cohesion at centromeric regions and recovery from checkpoint arrest induced by DNA damage or DNA replication defects; potential Cdc28p substrate [Source:SGD;Acc:S000001293]" Bcin02g04270 1330 Chromo/chromo shadow domain + Chromo domain-like + Histone deacetylase complex, subunit 2/3 Bcin02g04280 1565 WD40 repeat + NACHT nucleoside triphosphatase + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + Pyrrolo-quinoline quinone beta-propeller repeat + WD40 repeat, conserved site + G-protein beta WD-40 repeat + P-loop containing nucleoside triphosphate hydrolase Bcin02g04290 286 CAZy : PL7 //SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Concanavalin A-like lectin/glucanase domain + Alginate lyase 2 Bcin02g04300 145 Bcin02g04310 684 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin02g04320 546 SignalP-noTM Bcin02g04330 850 Bcin02g04340 507 Leucine-rich repeat domain, L domain-like Bcin02g04350 168 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin02g04360 410 yes SM cluster Melanin quatro//Protease Bcygh1, Yellow-green hydrolase, involved in DHN melanin biosynthesis Bcin02g04370 494 Bcin02g04380 411 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin02g04390 593 Bcrgs5, Regulator of G protein signalling Bcin02g04400 511 SignalP-noTM Carbohydrate-binding WSC + Domain of unknown function DUF1996 Bcin02g04410 548 Exonuclease V Bcin02g04420 366 Nucleoside phosphorylase domain Bcin02g04430 263 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin02g04440 246 CAZy : CBM1 //SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Cellulose-binding domain, fungal Bcin02g04450 605 CAZy : GT22 "Bcalg9, similar to yeast ALG9, Mannosyltransferase, involved in N-linked glycosylation; catalyzes both the transfer of seventh mannose residue on B-arm and ninth mannose residue on the C-arm from Dol-P-Man to lipid-linked oligosaccharides; mutation of the human ortholog causes type 1 congenital disorders of glycosylation [Source:SGD;Acc:S000005163]" Bcin02g04460 726 Signaling pathway "Bcnaf1, similar to yeast NAF1, RNA-binding protein required for the assembly of box H/ACA snoRNPs; thus required for pre-rRNA processing; forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p [Source:SGD;Acc:S000005068]" Bcin02g04470 434 Protein of unknown function DUF3445 Bcin02g04480 291 Mpv17/PMP22 Bcin02g04490 317 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B + Extradiol aromatic ring-opening dioxygenase, DODA type Bcin02g04500 316 BTB/POZ-like + BTB/POZ fold Bcin02g04510 202 Effector(V2)|Effector(V1) Nitroreductase-like + Nitroreductase + Nitroreductase Frm2/Hbn1-like Bcin02g04520 656 Oxidoreductase FAD/NAD(P)-binding + Flavoprotein pyridine nucleotide cytochrome reductase + FAD-binding, type 1 + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel + NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 Bcin02g04530 385 Sel1-like + Tetratricopeptide-like helical domain + Tetratricopeptide repeat Bcin02g04540 428 U3 snoRNA associated Bcin02g04550 883 SignalP-noTM//Early secretome Bcin02g04560 883 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB Bcin02g04570 319 Bcin02g04580 673 Bcin02g04590 512 GDP-fucose protein O-fucosyltransferase Bcin02g04600 191 Early secretome Protein of unknown function DUF1349 Bcin02g04610 589 AMP-dependent synthetase/ligase + AMP-binding, conserved site Bcin02g04620 75 Effector(V2)|Effector(V1) Bcin02g04630 88 Bcin02g04640 208 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Ubiquitin 3 binding protein But2, C-terminal Bcin02g04650 231 BTB/POZ-like + BTB/POZ fold Bcin02g04660 221 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin02g04670 263 Protease Peptidase C15, pyroglutamyl peptidase I-like Bcin02g04680 590 Transporter Amino acid transporter, transmembrane domain Bcin02g04690 153 Effector(V2)|Effector(V1)//Early secretome Ricin B lectin domain Bcin02g04700 915 Pleckstrin homology domain + Pleckstrin homology-like domain Bcin02g04710 414 DASH complex subunit Ask1 Bcin02g04720 123 Bcin02g04730 207 Effector(V2) GNAT domain + Acyl-CoA N-acyltransferase Bcin02g04740 305 Bcin02g04750 245 SM 0 Protein of unknown function DUF3328 Bcin02g04760 1517 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin02g04770 402 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal Bcin02g04780 230 Bcin02g04790 358 Poly(ADP-ribose) polymerase, catalytic domain Bcin02g04800 424 Protease//SignalP-noTM//Early secretome Peptidase M14, carboxypeptidase A + Proteinase inhibitor, carboxypeptidase propeptide + Proteinase inhibitor, propeptide Bcin02g04810 465 Early secretome Bcin02g04820 911 Bcin02g04830 299 "Bcyhi9, similar to yeast YHI9, Protein of unknown function; null mutant is defective in unfolded protein response; possibly involved in a membrane regulation metabolic pathway; member of the PhzF superfamily, though most likely not involved in phenazine production [Source:SGD;Acc:S000001071]" Bcin02g04840 586 Transporter Phosphate permease + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin02g04850 324 Effector(V2) Bcin02g04860 335 GNAT domain + Acyl-CoA N-acyltransferase Bcin02g04870 229 Linker histone H1/H5, domain H15 + Histone H5 + Winged helix-turn-helix DNA-binding domain Bcin02g04880 981 "Bcmss4, similar to yeast MSS4, Phosphatidylinositol-4-phosphate 5-kinase; involved in actin cytoskeleton organization and cell morphogenesis; multicopy suppressor of stt4 mutation [Source:SGD;Acc:S000002616]" Bcin02g04890 1345 Bcin02g04900 395 XPG/Rad2 endonuclease + XPG N-terminal + XPG-I domain + Helix-hairpin-helix motif, class 2 + XPG conserved site + 5'-3' exonuclease, C-terminal domain + Flap structure-specific endonuclease + PIN domain-like Bcin02g04910 428 Acyl-CoA oxidase/dehydrogenase, central domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase/oxidase, N-terminal Bcin02g04920 147 Effector(V2)|Effector(V1) Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like + Ubiquitin-conjugating enzyme, active site Bcin02g04930 581 yes Signaling pathway BcnoxB, NADPH oxidase Bcin02g04940 252 Bcin02g04950 189 Effector(V1) Bcin02g04960 204 Bcin02g04970 658 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin02g04980 794 Heterokaryon incompatibility Bcin02g04990 502 F-box domain Bcin02g05000 228 "Bcsys1, similar to yeast SYS1, Integral membrane protein of the Golgi; required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation [Source:SGD;Acc:S000003541]" Bcin02g05010 728 Bcin02g05020 370 Bcin02g05030 520 Gluconate transport inducer 1/Pac2 Bcin02g05040 511 "Bcslm5, similar to yeast SLM5, Mitochondrial asparaginyl-tRNA synthetase [Source:SGD;Acc:S000000618]" Bcin02g05050 304 Conserved hypothetical protein CHP02452 + Domain of unknown function DUF2263 Bcin02g05060 168 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin02g05070 964 yes Bcsfb3, subunit of COPII vesicles Bcin02g05080 934 "Bccft2, similar to yeast CFT2, Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein. [Source:SGD;Acc:S000004105]" Bcin02g05090 217 Effector(V2) Bcin02g05100 707 Copper amine oxidase + Copper amine oxidase, C-terminal + Copper amine oxidase, N2-terminal + Copper amine oxidase, N-terminal Bcin02g05110 748 yes Zn2/Cys6 + fungal trans transcription factor BcFtg1, Zn(2)-C6 fungal-type DNA-binding domain Bcin02g05130 491 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g05140 149 "Bcrpl28, similar to yeast RPL28, Ribosomal 60S subunit protein L28; homologous to mammalian ribosomal protein L27A and bacterial L15; may have peptidyl transferase activity; can mutate to cycloheximide resistance [Source:SGD;Acc:S000003071]" Bcin02g05150 483 "Bccdc7, similar to yeast CDC7, DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of the monopolin complex to kinetochores during meiosis I and as a gene-specific regulator of the meiosis-specific transcription factor Ndt80p [Source:SGD;Acc:S000002175]" Bcin02g05160 1206 "Bcycs4, similar to yeast YCS4, Subunit of the condensin complex; required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin, tRNA gene clustering at the nucleolus, and silencing at the mating type locus; required for replication slow zone (RSZ) breakage following Mec1p inactivation [Source:SGD;Acc:S000004262]" Bcin02g05170 352 "Bcoxr1, similar to yeast OXR1, Protein of unknown function required for oxidative damage resistance; required for normal levels of resistance to oxidative damage; null mutants are sensitive to hydrogen peroxide; member of a conserved family of proteins found in eukaryotes [Source:SGD;Acc:S000006117]" Bcin02g05180 323 "Bchem4, similar to yeast HEM4, Uroporphyrinogen III synthase; catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria [Source:SGD;Acc:S000005804]" Bcin02g05190 173 Effector(V2)|Effector(V1) "Bcerv1, similar to yeast ERV1, Flavin-linked sulfhydryl oxidase of the mitochondrial IMS; N-terminus is an intrinsically disordered domain that in the cytosol helps target Erv1p to mitochondria, and in the intermembrane space oxidizes Mia40p as part of a disulfide relay system that promotes intermembrane space retention of imported proteins; functional ortholog of human GFER (ALR) [Source:SGD;Acc:S000003261]" Bcin02g05200 412 Bcin02g05210 688 "Bclro1, similar to yeast LRO1, Acyltransferase that catalyzes diacylglycerol esterification; one of several acyltransferases that contribute to triglyceride synthesis; Lro1p and Dga1p can O-acylate ceramides; putative homolog of human lecithin cholesterol acyltransferase [Source:SGD;Acc:S000005291]" Bcin02g05220 205 Effector(V2)|Effector(V1) "Bcmak3, similar to yeast MAK3, Catalytic subunit of the NatC type N-terminal acetyltransferase; involved in subcellular targeting of select N-terminally acetylated substrates to the Golgi apparatus (Arl3p and Grh1p) and the inner nuclear membrane (Trm1p); required for replication of dsRNA virus [Source:SGD;Acc:S000006255]" Bcin02g05230 358 Protein of unknown function DUF1917 + Translation Initiation factor eIF- 4e-like domain Bcin02g05240 527 "Bcrrt2, similar to yeast RRT2, Methylesterase performing penultimate step of diphthamide biosynthesis; hydrolyzes methylated diphthine to produce diphthine and allows Dph6-catalyzed amidation reaction to occur; deletion leads to resistance to sordarin and accumulation of methylatediphthine; WD40 domain-containing protein; involved in endosomal recycling; forms complex with Rtt10p that functions in retromer-mediated pathway for recycling internalized cell-surface proteins [Source:SGD;Acc:S000000450]" Bcin02g05250 201 Bcin02g05260 1224 Protease WD40 repeat + Coatomer, WD associated region + Coatomer, alpha subunit, C-terminal + Cytochrome cd1-nitrite reductase-like, haem d1 domain + WD40/YVTN repeat-like-containing domain + Coatomer alpha subunit + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin02g05270 1491 CAZy : GT24 //SignalP-noTM "Bckre5, similar to yeast KRE5, Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects [Source:SGD;Acc:S000005863]" Bcin02g05280 256 Effector(V2)|Effector(V1) Bcin02g05290 358 Bcin02g05300 417 SignalP-noTM Six-bladed beta-propeller, TolB-like + Major royal jelly protein/Protein yellow Bcin02g05310 249 Bcin02g05320 808 Bcin02g05330 381 SignalP-noTM Bcin02g05340 552 SignalP-noTM Bcin02g05350 586 Bcin02g05360 351 Protease//SignalP-noTM Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin02g05370 324 Protein of unknown function DUF3425 Bcin02g05380 306 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin02g05390 251 Bcin02g05400 334 Bcin02g05410 262 Bcin02g05420 441 Bcin02g05430 380 Bcin02g05440 1057 Bcin02g05450 546 Bcin02g05460 678 Zn2/Cys6 transcription factor HMG-I/HMG-Y, DNA-binding, conserved site + Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin02g05470 99 Effector(V2)|Effector(V1) Bcin02g05480 1620 Bcin02g05490 578 P-loop containing nucleoside triphosphate hydrolase Bcin02g05500 453 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin02g05510 1247 SANT/Myb domain + Homeodomain-like + Myb-like domain + Myb domain Bcin02g05520 347 Bcin02g05530 318 ATPase, vacuolar ER assembly factor, Vma12 Bcin02g05540 456 "Bccoq1, similar to yeast COQ1, Hexaprenyl pyrophosphate synthetase; catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis [Source:SGD;Acc:S000000207]" Bcin02g05550 646 GNAT domain + Acyl-CoA N-acyltransferase + N-acetyltransferase ESCO, zinc-finger + N-acetyltransferase ESCO, acetyl-transferase domain Bcin02g05560 193 SignalP-noTM Bcin02g05570 736 Heterokaryon incompatibility Bcin02g05580 505 Bcin02g05590 260 Effector(V1) "Bcemg1, similar to yeast EMG1, Methyltransferase for rRNA; catalyzes methylation of the pseudouridine residue 1191 of 18S rRNA; member of the SPOUT methyltransferase family; required for maturation of 18S rRNA and for 40S ribosomal subunit production independently of methyltransferase activity; forms homodimers; human ortholog is mutated in Bowen-Conradi syndrome, and the equivalent mutation in yeast affects Emg1p dimerization and localization but not its methyltransferase activity [Source:SGD;Acc:S000004176]" Bcin02g05600 370 SignalP-noTM Bcin02g05610 770 SignalP-noTM Bcin02g05620 548 Transporter Amino acid/polyamine transporter I Bcin02g05630 239 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa LysM domain Bcin02g05640 518 BTB/POZ fold Bcin02g05650 235 Bcgst16, Glutathione S-transferase Bcin02g05660 160 Bcin02g05670 244 Bcin02g05680 417 Bcin02g05690 585 CAZy : GH13Energy Glycosyl hydrolase, family 13, catalytic domain + Glycosyl hydrolase, family 13, all-beta + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Maltogenic Amylase, C-terminal Bcin02g05700 521 Protein of unknown function DUF2434 Bcin02g05710 454 "Bccog5, similar to yeast COG5, Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments [Source:SGD;Acc:S000004996]" Bcin02g05720 658 Heterokaryon incompatibility Bcin02g05730 541 Amidase signature domain Bcin02g05740 539 Protease "Bcdal1, similar to yeast DAL1, Allantoinase; converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression [Source:SGD;Acc:S000001466]" Bcin02g05750 287 Ribonuclease H-like domain Bcin02g05760 188 Effector(V2)|Effector(V1) Bcin02g05770 798 Ankyrin repeat + Ankyrin repeat-containing domain Bcin02g05780 439 Aminotransferase class V domain + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase Bcin02g05790 160 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin02g05800 310 NmrA-like domain + NAD(P)-binding domain Bcin02g05810 312 Effector(V2)|Effector(V1) NAD(P)-binding domain Bcin02g05820 435 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin02g05830 303 RTA-like protein Bcin02g05840 314 Tocopherol O-methyltransferase + S-adenosyl-L-methionine-dependent methyltransferase Bcin02g05850 200 Bcin02g05860 370 CAZy : GH28PCW pectin//SignalP-noTM//Early secretome Bcpg6, Endopolygalacturonase Bcin02g05870 360 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin02g05880 136 Effector(V2)|Effector(V1)//Early secretome "Bchnt1, similar to yeast HNT1, Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002283]" Bcin02g05890 646 CRAL-TRIO domain + CRAL/TRIO, N-terminal domain Bcin02g05900 279 DASH complex subunit Dam1 Bcin02g05910 173 Cys2His2 transcription factor//Effector(V1) "Bcbud20, similar to yeast BUD20, C2H2-type zinc finger protein required for ribosome assembly; shuttling factor which associates with pre-60S particles in the nucleus, accompanying them to the cytoplasm; cytoplasmic dissociation of Bud20p requires Drg1p; N-terminus harbors a nuclear localization signal (NLS) and a nuclear export signal (NES); cytoplasmic Bud20p is reimported by Kap123-dependent pathway; involved in bud-site selection; diploid mutants display a random budding pattern; similar to human ZNF593 [Source:SGD;Acc:S000004064]" Bcin02g05920 783 Early secretome "Bcaco1, similar to yeast ACO1, Aconitase; required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; phosphorylated; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy [Source:SGD;Acc:S000004295]" Bcin02g05930 269 Protease "Bcrbd2, similar to yeast RBD2, Possible rhomboid protease; has similarity to eukaryotic rhomboid proteases including Pcp1p [Source:SGD;Acc:S000006167]" Bcin02g05940 642 GPI transamidase component Gaa1 Bcin02g05950 380 "Bcrpn9, similar to yeast RPN9, Non-ATPase regulatory subunit of the 26S proteasome; similar to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002835]" Bcin02g05960 383 NmrA-like domain + NAD(P)-binding domain Bcin02g05970 255 yes BcDamt, N6-adenine methyltransferase Bcin02g05980 298 Beta-lactamase-like Bcin02g05990 521 Protease "Bcubp10, similar to yeast UBP10, Ubiquitin-specific protease, deubiquitinates Ub-protein moieties; interacts with proteins that function in rRNA production and ribosome biogenesis; stabilizes Rpa190p, the largest subunit of RNAP I, by mediating its deubiquitination; controls PCNA deubiquitylation; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; localized to the nucleolus; human USP36 is a functional analog of Ubp10p [Source:SGD;Acc:S000005130]" Bcin02g06000 587 SignalP-noTM Domain of unknown function DUF2427 + Uncharacterised domain YCR061W, C-terminal Bcin02g06010 185 Bcin02g06020 196 "Bcmog1, similar to yeast MOG1, Conserved nuclear protein that interacts with GTP-Gsp1p; stimulates nucleotide release from Gsp1p; involved in nuclear protein import; nucleotide release is inhibited by Yrb1p [Source:SGD;Acc:S000003835]" Bcin02g06030 699 HMG (high mobility group) transcription factor Domain of unknown function SprT-like + High mobility group box domain Bcin02g06040 868 DNA ligase, ATP-dependent + DNA ligase, ATP-dependent, N-terminal + DNA ligase, ATP-dependent, C-terminal + DNA ligase, ATP-dependent, central + Nucleic acid-binding, OB-fold + DNA ligase, ATP-dependent, conserved site Bcin02g06050 803 RINT-1/TIP-20 Bcin02g06060 119 Effector(V1) Ribosomal protein S26e Bcin02g06070 155 Effector(V1) "Bcrps31, similar to yeast RPS31, Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B; homologous to mammalian ribosomal protein S27A, no bacterial homolog [Source:SGD;Acc:S000004157]" Bcin02g06080 133 Effector(V1) Ribosome-assembly protein 3 Bcin02g06090 263 Bcin02g06110 1346 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin02g06120 113 Bcin02g06130 468 Oxysterol-binding protein + Oxysterol-binding protein, conserved site Bcin02g06140 805 CP2 transcription factor Bcin02g06150 733 Kinesin motor domain + RuvA domain 2-like + Kinesin-like protein KIF22 (Kid) + P-loop containing nucleoside triphosphate hydrolase Bcin02g06160 259 Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin02g06170 1411 "Bcsmc4, similar to yeast SMC4, Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for tRNA gene clustering at the nucleolus; potential Cdc28p substrate [Source:SGD;Acc:S000004076]" Bcin02g06180 313 ELYS-like domain Bcin02g06190 588 Zinc finger, CCCH-type Bcin02g06200 223 Bcin02g06210 257 Protein-L-isoaspartate(D-aspartate) O-methyltransferase + S-adenosyl-L-methionine-dependent methyltransferase Bcin02g06220 401 Bcin02g06230 1293 Protease "Bcubp2, similar to yeast UBP2, Ubiquitin-specific protease; removes ubiquitin from ubiquitinated proteins; deubiquitinates Rsp5p and is required for MVB sorting of membrane proteins; can cleave polyubiquitin and has isopeptidase activity [Source:SGD;Acc:S000005650]" Bcin02g06240 191 Effector(V2)|Effector(V1) Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 Bcin02g06250 246 Effector(V2) CARP motif + Tubulin binding cofactor C-like domain + C-CAP/cofactor C-like domain + Tubulin-specific chaperone C Bcin02g06260 148 Effector(V2)|Effector(V1) Mediator complex, subunit Med9 Bcin02g06270 533 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent + Metalloenzyme + BPG-independent PGAM, N-terminal + Alkaline phosphatase-like, alpha/beta/alpha + Alkaline-phosphatase-like, core domain Bcin02g06280 210 Effector(V2) HotDog domain Bcin02g06290 563 AMP-dependent synthetase/ligase Bcin02g06300 377 Bcin02g06310 438 Fatty acid desaturase, type 1 Bcin02g06320 505 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g06330 559 Lipoxygenase + Lipoxygenase, C-terminal Bcin02g06340 316 SignalP-noTM Bcprd6, Peroxidase Bcin02g06350 307 AdipoR/Haemolysin-III-related Bcin02g06360 897 "Bcvac14, similar to yeast VAC14, Enzyme regulator; involved in synthesis of phosphatidylinositol 3,5-bisphosphate, in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; binds negative (Fig4p) and positive (Fab1p) regulators of PtdIns(3,5)P(2) to control endolysosome function; similar to mammalian Vac14p [Source:SGD;Acc:S000004378]" Bcin02g06370 104 Effector(V1) Bcin02g06380 563 Cytochrome b5-like heme/steroid binding domain + Fatty acid desaturase, type 1 + Fatty acid desaturase Bcin02g06390 221 Effector(V2)|Effector(V1) Bcin02g06400 510 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain + Dihydrolipoamide dehydrogenase + Pyridine nucleotide-disulphide oxidoreductase, class I, active site + FAD/NAD-linked reductase, dimerisation domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin02g06410 867 "Bcsgd1, similar to yeast SGD1, Essential nuclear protein; required for biogenesis of the small ribosomal subunit; has a possible role in the osmoregulatory glycerol response; putative homolog of human NOM1 which is implicated in acute myeloid leukemia [Source:SGD;Acc:S000004328]" Bcin02g06420 157 Effector(V1) Signal recognition particle, SRP14 subunit + Signal recognition particle, SRP9/SRP14 subunit Bcin02g06430 441 Bcin02g06440 488 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin02g06450 263 "Bccoq9, similar to yeast COQ9, Protein required for ubiquinone biosynthesis and respiratory growth; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; ubiquinone is also known as coenzyme Q [Source:SGD;Acc:S000004191]" Bcin02g06460 1173 RecF/RecN/SMC, N-terminal + Structural maintenance of chromosomes protein 6 + P-loop containing nucleoside triphosphate hydrolase Bcin02g06470 604 yes BcStr2, BcStr2, cystathionine gamma-synthase, key enzyme in methioinine biosynthesis Bcin02g06480 1124 "Bcutp22, similar to yeast UTP22, Component of the small-subunit processome; required for nuclear export of tRNAs; may facilitate binding of Utp8p to aminoacylated tRNAs and their delivery to Los1p for export; conserved from yeast to mammals [Source:SGD;Acc:S000003322]" Bcin02g06490 427 "Bctsr4, similar to yeast TSR4, Cytoplasmic protein required for correct processing of 20S pre-rRNA; protein required for processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; essential gene in S288C background but not in CEN.PK2 [Source:SGD;Acc:S000005382]" Bcin02g06500 245 Eukaryotic translation initiation factor 3 subunit K + Winged helix-turn-helix DNA-binding domain + Translation initiation factor 3, subunit 12, N-terminal, eukaryotic + Armadillo-type fold + CSN8/PSMD8/EIF3K Bcin02g06510 744 Bcin02g06520 558 Bcin02g06530 419 Protease Caspase-like domain Bcin02g06540 1476 Spindle associated + Pericentrin/AKAP-450 centrosomal targeting domain Bcin02g06550 644 SGT1 Bcin02g06560 425 Bcin02g06570 334 "Bctan1, similar to yeast TAN1, Putative tRNA acetyltransferase; RNA-binding protein required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs but not required for the same modification in 18S rRNA; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003201]" Bcin02g06580 572 Thiamine pyrophosphate enzyme, C-terminal TPP-binding + Thiamine pyrophosphate enzyme, central domain + Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain + Thiamine pyrophosphate (TPP)-dependent enzyme + DHS-like NAD/FAD-binding domain + Thiamin diphosphate-binding fold Bcin02g06590 1855 yes Bcbck1, Serine/threonine MAP kinase kinase kinase involved in CW1 pathway Bcin02g06600 297 Bcin02g06610 530 SignalP-noTM "Bcjem1, similar to yeast JEM1, DnaJ-like chaperone required for nuclear membrane fusion during mating; localizes to the ER membrane; exhibits genetic interactions with KAR2 [Source:SGD;Acc:S000003609]" Bcin02g06620 479 "Bcldb17, similar to yeast LDB17, Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck [Source:SGD;Acc:S000002305]" Bcin02g06630 869 Pleckstrin homology domain + Pleckstrin homology-like domain + Phosphatidylinositol 4,5-bisphosphate-binding protein Slm1/Slm2 Bcin02g06640 787 "Bcths1, similar to yeast THS1, Threonyl-tRNA synthetase; essential cytoplasmic protein [Source:SGD;Acc:S000001340]" Bcin02g06650 221 Effector(V1) "Bcgar1, similar to yeast GAR1, Protein component of the H/ACA snoRNP pseudouridylase complex; involved in the modification and cleavage of the 18S pre-rRNA [Source:SGD;Acc:S000001131]" Bcin02g06660 241 Effector(V2) "Bccho1, similar to yeast CHO1, Phosphatidylserine synthase; functions in phospholipid biosynthesis; catalyzes the reaction CDP-diaclyglycerol + L-serine = CMP + L-1-phosphatidylserine, transcriptionally repressed by myo-inositol and choline [Source:SGD;Acc:S000000828]" Bcin02g06670 773 Jacalin-like lectin domain + Uncharacterised protein family, zinc metallopeptidase-like Bcin02g06680 377 Transcription factor Nrm1/Whi5 Bcin02g06690 539 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin02g06700 339 Alpha/Beta hydrolase fold Bcin02g06710 314 Bcin02g06720 1247 "Bcpom152, similar to yeast POM152, Glycoprotein subunit of transmembrane ring of nuclear pore complex; contributes to nucleocytoplasmic transport, nuclear pore complex (NPC) biogenesis and spindle pole body duplication; homologous to human NUP210 [Source:SGD;Acc:S000004736]" Bcin02g06730 480 Protease Peptidase C12, ubiquitin carboxyl-terminal hydrolase Bcin02g06740 605 F-box domain + Hemimethylated DNA-binding domain + Protein SirB1, N-terminal Bcin02g06750 446 Zinc finger, RING-type + SPX, N-terminal + Zinc finger, RING/FYVE/PHD-type + Zinc finger, C3HC4 RING-type Bcin02g06760 540 Cys2His2 transcription factor "Bcjjj1, similar to yeast JJJ1, Co-chaperone that stimulates the ATPase activity of Ssa1p; required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis [Source:SGD;Acc:S000005171]" Bcin02g06770 439 yes Protease Bcatg4, Autophagy-related gene, cysteine protease Bcin02g06780 779 "Bcsqs1, similar to yeast SQS1, Protein that stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles; relocalizes from nucleus to nucleolus upon DNA replication stress [Source:SGD;Acc:S000005168]" Bcin02g06790 140 Effector(V1) Histone H2B + Histone core + Histone-fold Bcin02g06800 136 Effector(V2)|Effector(V1) Histone H2A + Histone core + Histone-fold + Histone H2A, C-terminal domain + Histone H2A conserved site Bcin02g06810 99 Effector(V1) Complex 1 LYR protein + NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 Bcin02g06820 431 "Bckgd2, similar to yeast KGD2, Dihydrolipoyl transsuccinylase; component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated [Source:SGD;Acc:S000002555]" Bcin02g06830 231 SignalP-noTM Cerato-platanin Bcin02g06840 518 Coenzyme A transferase active site + Coenzyme A transferase family I + 3-oxoacid CoA-transferase, subunit B + 3-oxoacid CoA-transferase, subunit A + 3-oxoacid CoA-transferase Bcin02g06850 146 Effector(V2)|Effector(V1) Bcin02g06860 435 Early secretome Acetamidase/Formamidase Bcin02g06870 397 Bcin02g06880 631 Inheritance of peroxisomes protein 1 Bcin02g06890 672 "Bccue3, similar to yeast CUE3, Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination [Source:SGD;Acc:S000003078]" Bcin02g06900 116 Effector(V2)|Effector(V1) "Bcrps20, similar to yeast RPS20, Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; homologous to mammalian ribosomal protein S20 and bacterial S10 [Source:SGD;Acc:S000001007]" Bcin02g06910 468 CAZy : GH17FCW //SignalP-noTM Glycoside hydrolase, family 17 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin02g06920 519 Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase Bcin02g06930 1932 CAZy : GT48 Glycosyl transferase, family 48 + 1,3-beta-glucan synthase subunit FKS1-like, domain-1 Bcin02g06940 540 CAZy : GH72,CBM43FCW //SignalP-noTM//Early secretome "Bcgas1, similar to yeast GAS1, Beta-1,3-glucanosyltransferase; required for cell wall assembly and also has a role in transcriptional silencing; localizes to cell surface via a glycosylphosphatidylinositol (GPI) anchor; also found at nuclear periphery; genetic interactions with histone H3 lysine acetyltransferases GCN5 and SAS3 indicate previously unsuspected functions for Gas1 in DNA damage response and cell cycle regulation [Source:SGD;Acc:S000004924]" Bcin02g06950 303 Transporter Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin02g06960 357 Protease "Bcotu1, similar to yeast OTU1, Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p; may contribute to regulation of protein degradation by deubiquitylating substrates that have been ubiquitylated by Ufd2p; member of the Ovarian Tumor (OTU) family; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001850]" Bcin02g06970 905 Bromo adjacent homology (BAH) domain + Bromodomain Bcin02g06980 765 "Bccog3, similar to yeast COG3, Essential component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments [Source:SGD;Acc:S000000959]" Bcin02g06990 589 "Bcfmp25, similar to yeast FMP25, Protein required for assembly of respiratory complex III; mitochondrial inner membrane protein; required for an early step in assembly of respiratory complex III (cytochrome bc1 complex); mRNA is targeted to mitochondria [Source:SGD;Acc:S000004067]" Bcin02g07000 910 Bcin02g07010 998 Bcin02g07020 465 Bcin02g07030 503 Bcin02g07040 1273 "Bcvps41, similar to yeast VPS41, Subunit of the HOPS endocytic tethering complex; vacuole membrane protein that functions as a Rab GTPase effector, interacting specifically with the GTP-bound conformation of Ypt7p, facilitating tethering, docking and promoting membrane fusion events at the late endosome and vacuole; required for both membrane and protein trafficking; Yck3p-mediated phosphorylation regulates the organization of vacuolar fusion sites [Source:SGD;Acc:S000002487]" Bcin02g07050 412 Protein of unknown function DUF155 Bcin02g07060 792 Heterokaryon incompatibility Bcin02g07070 280 SignalP-noTM//Effector(V1) Bcin02g07080 678 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin02g07090 413 NADH:flavin oxidoreductase/NADH oxidase, N-terminal + Aldolase-type TIM barrel Bcin02g07100 256 CAZy : CE12PCW hemicellulose or pectin//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome SGNH hydrolase-type esterase domain Bcin02g07110 301 Bcin02g07120 268 Bcin02g07130 254 Effector(V2) Class I glutamine amidotransferase-like + ThiJ/PfpI family-like Bcin02g07140 553 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin02g07150 557 Chaperonin TCP-1, conserved site + Chaperonin Cpn60/TCP-1 family + T-complex protein 1, eta subunit + Chaperone tailless complex polypeptide 1 (TCP-1) + GroEL-like apical domain + TCP-1-like chaperonin intermediate domain + GroEL-like equatorial domain Bcin02g07160 621 Effector(V2) "Bcspt10, similar to yeast SPT10, Putative histone acetylase with a role in transcriptional silencing; sequence-specific activator of histone genes, binds specifically and cooperatively to pairs of UAS elements in core histone promoters, functions at or near the TATA box [Source:SGD;Acc:S000003663]" Bcin02g07170 275 Effector(V2)|Effector(V1) Bcin02g07180 284 GNAT domain + Acyl-CoA N-acyltransferase Bcin02g07190 813 Bcin02g07200 490 Bcin02g07210 349 Aldose 1-/Glucose-6-phosphate 1-epimerase + Galactose mutarotase-like domain + Glycoside hydrolase-type carbohydrate-binding, subgroup + Aldose 1-epimerase, conserved site Bcin02g07220 554 Cytochrome b5-like heme/steroid binding domain + Acyl-CoA oxidase/dehydrogenase, central domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase/oxidase, N-terminal Bcin02g07230 594 CAZy : GH16FCW //SignalP-noTM Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin02g07240 222 Bcin02g07250 522 Bcin02g07260 187 Bcin02g07270 1393 WD40 repeat + Quinonprotein alcohol dehydrogenase-like superfamily + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat + P-loop containing nucleoside triphosphate hydrolase Bcin02g07280 304 Effector(V2)|Effector(V1) Bcin02g07290 1580 Sec7 domain + Pleckstrin homology-like domain + Sec7 domain, alpha orthogonal bundle Bcin02g07300 108 Effector(V1) Bcin02g07310 435 Protease//SignalP-noTM Bcap6, Aspartic proteinase Bcin02g07320 350 RTA-like protein Bcin02g07330 199 Prion-inhibition and propagation, HeLo domain Bcin02g07340 312 Bcin02g07350 245 Haloacid dehalogenase, type II + HAD hydrolase, subfamily IA + Phosphoglycolate phosphatase, domain 2 + HAD-like domain Bcin02g07360 265 Effector(V2)|Effector(V1) Bcin02g07380 614 "Bcpet112, similar to yeast PET112, Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog [Source:SGD;Acc:S000000176]" Bcin02g07390 710 Bcin02g07400 1143 yes GATA zinc finger transcription factor//Signaling pathway Bcwcl1, GATA zinc finger transcription factor, White collar-like 1, potential blue light sensor Bcin02g07410 1097 "Bcpse1, similar to yeast PSE1, Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p [Source:SGD;Acc:S000004925]" Bcin02g07420 482 CBS domain + Sds23 Bcin02g07430 644 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin02g07440 597 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g07450 195 Bcin02g07460 444 Ubiquitin-like + Ubiquitin + Ubiquitin-related domain Bcin02g07470 201 SignalP-noTM Bcin02g07480 254 Effector(V1) Oxoglutarate/iron-dependent dioxygenase + Prolyl 4-hydroxylase, alpha subunit Bcin02g07490 261 SM 0 Protein of unknown function DUF3328 Bcin02g07500 239 Effector(V1) Bcin02g07510 261 SM 0 Protein of unknown function DUF3328 Bcin02g07520 471 CAZy : CBM35,GH26PCW hemicellulose//SignalP-noTM//Early secretome Glycoside hydrolase, family 26 + Carbohydrate binding module family 6 + Galactose-binding domain-like + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Endoglucanase H/Glycosyl hydrolase family 26 Bcin02g07530 77 Effector(V1) Ubiquitin-like + Ubiquitin-related domain Bcin02g07540 768 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin02g07550 680 Phox/Bem1p + CBS domain Bcin02g07560 365 "Bcmrp4, similar to yeast MRP4, Mitochondrial ribosomal protein of the small subunit [Source:SGD;Acc:S000000996]" Bcin02g07570 303 Bcin02g07580 191 Effector(V1) Cytochrome oxidase biogenesis protein, Cox20 subunit + Cox20/FAM36A Bcin02g07590 2220 DNA-directed DNA polymerase, family B, exonuclease domain + DNA-directed DNA polymerase, family B, multifunctional domain + DNA-directed DNA polymerase, family B + Ribonuclease H-like domain + DNA polymerase epsilon, catalytic subunit A, C-terminal + DNA polymerase, palm domain + DNA polymerase epsilon catalytic subunit Bcin02g07600 256 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin02g07610 507 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin02g07620 521 Protease//SignalP-noTM Cholinesterase + Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin02g07630 408 SignalP-noTM Bcin02g07640 663 CAZy : AA1 //SignalP-noTM//Early secretome Bclcc7, Laccase/ Multicopper oxidase Bcin02g07650 208 Bcin02g07660 1933 "Bcapc1, similar to yeast APC1, Largest subunit of the Anaphase-Promoting Complex/Cyclosome; APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis; localizes to nuclear foci that become diffuse upon DNA replication stress [Source:SGD;Acc:S000005116]" Bcin02g07670 157 SignalP-noTM//Effector(V2) Bcin02g07680 148 Effector(V2)|Effector(V1) Ankyrin repeat + Ankyrin repeat-containing domain Bcin02g07690 325 Crotonase superfamily + ClpP/crotonase-like domain Bcin02g07700 319 yes CAZy : GH43PCW hemicellulose or pectin//SignalP-noTM//Early secretome Bcara1, Alpha-1,5-L-endo-arabinanase Bcin02g07710 716 Six-bladed beta-propeller, TolB-like + Translation initiation factor 2A + Translation initiation factor, beta propellor-like domain Bcin02g07720 615 Transporter "Bcyhk8, similar to yeast YHK8, Presumed antiporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; expression of gene is up-regulated in cells exhibiting reduced susceptibility to azoles [Source:SGD;Acc:S000001090]" Bcin02g07730 651 WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin02g07740 397 Bcin02g07750 1867 Bcin02g07760 445 Acyltransferase 3 Bcin02g07770 244 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Bcnep2, Necrosis- and ethylene-inducing protein 2 precursor Bcin02g07780 446 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin02g07790 1342 Carbohydrate-binding WSC + Galactose-binding domain-like Bcin02g07800 254 Bcin02g07810 280 S-adenosyl-L-methionine-dependent methyltransferase Bcin02g07820 259 Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin02g07830 368 Bcin02g07840 92 Bcin02g07850 334 Bcin02g07860 824 "Bcrrp6, similar to yeast RRP6, Nuclear exosome exonuclease component; has 3'-5' exonuclease activity that is regulated by Lrp1p; involved in RNA processing, maturation, surveillance, degradation, tethering, and export; role in sn/snoRNAs precursor degradation; forms a stable heterodimer with Lrp1p; has similarity to E. coli RNase D and to human PM-Sc1 100 (EXOSC10); mutant displays reduced transcription elongation in the G-less-based [Source:SGD;Acc:S000005527]" Bcin02g07870 80 Mitochondrial distribution/morphology family 35/apoptosis Bcin02g07880 720 "Bcgpi1, similar to yeast GPI1, Membrane protein involved in the synthesis of GlcNAc-PI; N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI) is the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs [Source:SGD;Acc:S000003448]" Bcin02g07890 143 Bcin02g07900 457 CAZy : GH76FCW Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase + Mannan endo-1,6-alpha-mannosidase Bcin02g07910 347 Bcin02g07920 389 Bcin02g07930 293 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin02g07940 329 Transporter Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin02g07950 94 Bcin02g07960 862 "Bcrad54, similar to yeast RAD54, DNA-dependent ATPase that stimulates strand exchange; modifies the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family of DNA translocases; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000003131]" Bcin02g07970 124 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bhp1, Hydrophobin class I Bcin02g07980 612 Bcin02g07990 544 "Bcrrp14, similar to yeast RRP14, Essential protein, constituent of 66S pre-ribosomal particles; interacts with proteins involved in ribosomal biogenesis and cell polarity; member of the SURF-6 family [Source:SGD;Acc:S000001565]" Bcin02g08000 352 "Bcvps74, similar to yeast VPS74, Golgi phosphatidylinositol-4-kinase effector and PtdIns4P sensor; interacts with the cytosolic domains of cis and medial glycosyltransferases, and in the PtdIns4P-bound state mediates the targeting of these enzymes to the Golgi; interacts with the catalytic domain of Sac1p, the major cellular PtdIns4P phosphatase, to direct dephosphosphorylation of the Golgi pool of PtdIns4P; tetramerization required for function; ortholog of human GOLPH3/GPP34/GMx33 [Source:SGD;Acc:S000002780]" Bcin02g08010 138 Effector(V1) "Bcacp1, similar to yeast ACP1, Mitochondrial matrix acyl carrier protein; involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p [Source:SGD;Acc:S000001675]" Bcin02g08020 229 Effector(V2)|Effector(V1) NADH-quinone oxidoreductase, chain I + 4Fe-4S ferredoxin-type, iron-sulphur binding domain + 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Bcin02g08030 124 Effector(V2)|Effector(V1) Bcin02g08040 574 FAD-binding 8 + Ferric reductase, NAD binding + Ferric reductase transmembrane component-like domain + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel Bcin02g08050 338 LETM1-like + Letm1 ribosome-binding domain Bcin02g08060 838 "Bcnab3, similar to yeast NAB3, RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing; Nrd1-Nab3 pathway appears to have a role in rapid suppression of some genes when cells are shifted to poor growth conditions, indicating role for Nrd1-Nab3 in regulating cellular response to nutrient availability [Source:SGD;Acc:S000006111]" Bcin02g08070 209 Peptide chain release factor class I/class II Bcin02g08080 429 Bcin02g08090 430 Bccmk2, Ca2+dependent kinase Bcin02g08100 153 Effector(V2)|Effector(V1) Bcin02g08110 400 "Bcutp6, similar to yeast UTP6, Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA [Source:SGD;Acc:S000002857]" Bcin02g08120 956 "Bccwh43, similar to yeast CWH43, Putative sensor/transporter protein involved in cell wall biogenesis; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion [Source:SGD;Acc:S000000610]" Bcin02g08130 440 "Bcaur1, similar to yeast AUR1, Phosphatidylinositol:ceramide phosphoinositol transferase; required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance; also known as IPC synthase [Source:SGD;Acc:S000001487]" Bcin02g08140 453 Bcin02g08150 1418 "Bcski3, similar to yeast SKI3, Ski complex component and TPR protein; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, TTC37, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome [Source:SGD;Acc:S000006393]" Bcin02g08160 765 CAZy : GH5PCW/FCW Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Glycoside hydrolase, family 5, conserved site Bcin02g08170 355 yes Signaling pathway Bmp1, MAP kinase Bcin02g08180 742 Clathrin/coatomer adaptor, adaptin-like, N-terminal + Armadillo-like helical + Armadillo-type fold + AP-1, 2,4 complex subunit beta + AP complex subunit beta Bcin02g08190 53 Effector(V1) Bcin02g08200 110 Effector(V2)|Effector(V1) "Bcfra2, similar to yeast FRA2, Protein involved in negative regulation of iron regulon transcription; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; null mutant fails to repress iron regulon and is sensitive to nickel [Source:SGD;Acc:S000003188]" Bcin02g08210 308 "Bcnif3, similar to yeast NIF3, Protein of unknown function; similar to Listeria monocytogenes major sigma factor (rpoD gene product); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000003189]" Bcin02g08220 294 Vacuolar protein sorting-associated protein 51 Bcin02g08230 567 Protease//SignalP-noTM//Early secretome Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin02g08240 941 Zinc finger, MYND-type + OTT_1508-like deaminase Bcin02g08250 278 Bcin02g08260 452 Proteasome component (PCI) domain + Winged helix-turn-helix DNA-binding domain + Eukaryotic translation initiation factor 3 subunit E + Eukaryotic translation initiation factor 3 subunit E, N-terminal Bcin02g08270 138 Effector(V2)|Effector(V1) Ribosomal protein L49/IMG2 Bcin02g08280 1041 "Bcswi1, similar to yeast SWI1, Subunit of the SWI/SNF chromatin remodeling complex; regulates transcription by remodeling chromatin; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; can form the prion [SWI+]; human homolog ARID1A is a candidate tumor suppressor gene in breast cancer [Source:SGD;Acc:S000005937]" Bcin02g08290 282 EVE domain + PUA-like domain Bcin02g08300 1252 "Bcmsn5, similar to yeast MSN5, Karyopherin; involved in nuclear import and export of proteins, including import of replication protein A and export of Far1p and transcription factors Swi5p, Swi6p, Msn2p, and Pho4p; required for re-export of mature tRNAs after their retrograde import from the cytoplasm; exportin-5 homolog [Source:SGD;Acc:S000002743]" Bcin02g08310 714 yes Zn2/Cys6 transcription factor//Signaling pathway Bcltf6, Light-responsive Zn2/Cys6 transcription factor Bcin02g08320 130 Bcin02g08330 953 von Willebrand factor, type A + Zinc finger, Sec23/Sec24-type + Sec23/Sec24, trunk domain + Sec23/Sec24, helical domain + Gelsolin-like domain + Sec23/Sec24 beta-sandwich + ADF-H/Gelsolin-like domain Bcin02g08340 523 yes CAZy : GT20 Bctps1, Trehalose-6-phosphatesynthase Bcin02g08350 178 Effector(V2)|Effector(V1) GNAT domain + Acyl-CoA N-acyltransferase Bcin02g08360 967 yes Bcfrq1, Frequency-like, protein implicated in the circadian clock Bcin02g08370 180 Effector(V2)|Effector(V1) Bcprx7, Peroxiredoxin (Redoxin) Bcin02g08380 384 CAZy : GH93PCW hemicellulose or pectin//SignalP-noTM//Early secretome Sialidases Bcin02g08390 556 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin02g08400 516 Zinc finger, RING-type + Zinc finger, C6HC-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site + E3 ubiquitin ligase RBR family Bcin02g08410 288 "Bcmam33, similar to yeast MAM33, Acidic protein of the mitochondrial matrix; involved in oxidative phosphorylation; related to the human complement receptor gC1q-R [Source:SGD;Acc:S000001332]" Bcin02g08420 181 "Bctma16, similar to yeast TMA16, Protein of unknown function that associates with ribosomes [Source:SGD;Acc:S000005778]" Bcin02g08430 768 XPG/Rad2 endonuclease + XPG N-terminal + XPG-I domain + Helix-hairpin-helix motif, class 2 + XPG conserved site + 5'-3' exonuclease, C-terminal domain + PIN domain-like + Exonuclease 1 Bcin02g08440 336 "Bcbsd2, similar to yeast BSD2, Heavy metal ion homeostasis protein; facilitates trafficking of Smf1p and Smf2p metal transporters to vacuole where they are degraded; acts as an adaptor protein with Rsp5p in the regulated endocytosis of Smf1p and is itself ubiquitylated by Rsp5p; controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification [Source:SGD;Acc:S000000494]" Bcin02g08450 115 Effector(V2)|Effector(V1) Bcin02g08460 300 Transporter Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin02g08470 663 "Bchpc2, similar to yeast HPC2, Subunit of the HIR complex; HIR is a nucleosome assembly complex involved in regulation of histone gene transcription; mutants display synthetic defects with subunits of FACT, a complex that allows passage of RNA Pol II through nucleosomes [Source:SGD;Acc:S000000419]" Bcin02g08480 453 "Bcrba50, similar to yeast RBA50, Protein involved in transcription; interacts with RNA polymerase II subunits Rpb2p, Rpb3, and Rpb11p; has similarity to human RPAP1 [Source:SGD;Acc:S000002935]" Bcin02g08490 313 BTB/POZ-like + BTB/POZ fold Bcin02g08500 208 SignalP-TM VanZ-like Bcin02g08510 1128 "Bcspt7, similar to yeast SPT7, Subunit of the SAGA transcriptional regulatory complex; involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex [Source:SGD;Acc:S000000285]" Bcin02g08520 123 "Bcyke2, similar to yeast YKE2, Subunit of the heterohexameric Gim/prefoldin protein complex; involved in the folding of alpha-tubulin, beta-tubulin, and actin; prefoldin complex also localizes to chromatin of actively transcribed genes in the nucleus and facilitates transcriptional elongation [Source:SGD;Acc:S000004190]" Bcin02g08530 430 "Bcvps4, similar to yeast VPS4, AAA-ATPase involved in multivesicular body (MVB) protein sorting; ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism [Source:SGD;Acc:S000006377]" Bcin02g08540 510 "Bcnop56, similar to yeast NOP56, Essential evolutionarily-conserved nucleolar protein; component of the box C/D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects [Source:SGD;Acc:S000004187]" Bcin02g08550 356 Bcin02g08560 650 FAD-binding 8 + Ferric reductase, NAD binding + Ferric reductase transmembrane component-like domain + Ferredoxin reductase-type FAD-binding domain Bcin02g08570 341 yes Bcsec14, involved in protein secretion Bcin02g08580 147 Effector(V1) "Bcpac10, similar to yeast PAC10, Part of the heteromeric co-chaperone GimC/prefoldin complex; complex promotes efficient protein folding [Source:SGD;Acc:S000003310]" Bcin02g08590 398 yes Protease//SignalP-noTM//Early secretome Bcap2, Aspartic proteinase Bcin02g08600 477 "Bcshm2, similar to yeast SHM2, Cytosolic serine hydroxymethyltransferase; converts serine to glycine plus 5,10 methylenetetrahydrofolate; major isoform involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis [Source:SGD;Acc:S000004048]" Bcin02g08610 380 DNA-directed RNA polymerase I, subunit RPA34.5 Bcin02g08620 776 "Bcgrc3, similar to yeast GRC3, Polynucleotide kinase present on rDNA; required for efficient transcription termination by RNA polymerase I; functions with Las1p in a conserved mechanism to modulate rRNA processing and ribosome biogenesis; required for cell growth; mRNA is cell-cycle regulated [Source:SGD;Acc:S000003958]" Bcin02g08630 577 Protein of unknown function DUF2410 Bcin02g08640 130 Effector(V2)|Effector(V1) Protein of unknown function DUF167 Bcin02g08650 647 yes Signaling pathway Bcskn7, Response regulator Bcin02g08660 107 Effector(V1) Bcin02g08670 750 "Bcgcd6, similar to yeast GCD6, Catalytic epsilon subunit of the translation initiation factor eIF2B; eIF2B is the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000002619]" Bcin02g08680 128 Effector(V2)|Effector(V1) Bcin02g08690 421 "Bcrpt3, similar to yeast RPT3, ATPase of the 19S regulatory particle of the 26S proteasome; one of ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B [Source:SGD;Acc:S000002802]" Bcin02g08700 133 Bcin02g08710 687 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin02g08720 228 Kinetochore Mis14 Bcin02g08730 456 "Bctrm10, similar to yeast TRM10, tRNA methyltransferase; methylates the N-1 position of guanine at position 9 in tRNAs; protein abundance increases in response to DNA replication stress; member of the SPOUT (SpoU-TrmD) methyltransferase family; human ortholog TRMT10A plays a role in the pathogenesis of microcephaly and early onset diabetes; an 18-mer originates from the TRM10 locus; genetic analysis shows the 18-mer is the translation regulator [Source:SGD;Acc:S000005453]" Bcin02g08740 923 "Bcmsh2, similar to yeast MSH2, Protein that binds to DNA mismatches; forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity and involved in interstrand cross-link repair; Msh2p-Msh6p binds to and hydrolyzes ATP [Source:SGD;Acc:S000005450]" Bcin02g08750 1322 Transporter ABC transporter-like + AAA+ ATPase domain + ABC-2 type transporter + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin02g08760 938 yes Zn2/Cys6 transcription factor + Cys2His2 + Fungal_trans//SM cluster Melanin bis Bcsmr1, Zn2/Cys6 transcription factor, Sclerotial Melanin Regulator Bcin02g08770 2147 yes SM cluster Melanin bis (KE) Bcpks12, Polyketide synthase, involved in DHN melanin biosynthesis Bcin02g08780 386 SM cluster PKS18 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain Bcin02g08790 107 SM cluster PKS18//Effector(V2)|Effector(V1) Antibiotic biosynthesis monooxygenase-like domain + Dimeric alpha-beta barrel Bcin02g08800 409 SM cluster PKS18//SignalP-noTM Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin02g08810 553 Transporter//SM cluster PKS18 Amino acid/polyamine transporter I + Amino acid permease, fungi + Amino acid permease, conserved site + Amino acid permease/ SLC12A domain Bcin02g08820 545 Transporter//SM cluster PKS18 Amino acid/polyamine transporter I Bcin02g08830 2532 SM cluster PKS18 (KE)//Protease Bcpks18, Polyketide synthase Bcin02g08840 355 SM cluster PKS18 Bcin02g08850 396 SM cluster PKS18 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin02g08860 454 Bcin02g08870 467 Aminoglycoside phosphotransferase + Tyrosine-protein kinase, active site + Protein kinase-like domain Bcin02g08880 361 Bcin02g08890 226 SM 0//Effector(V2)|Effector(V1) Protein of unknown function DUF3328 Bcin02g08900 244 SM 0 Protein of unknown function DUF3328 Bcin02g08910 59 SignalP-noTM Bcin02g08920 498 Cytochrome P450 + Cytochrome P450, E-class, CYP52 + Cytochrome P450, conserved site Bcin02g08930 507 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g08940 612 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin02g08950 532 Transporter Sugar/inositol transporter + General substrate transporter + Major facilitator superfamily domain Bcin02g08960 1057 CAZy : GH2PCW/FCW Beta galactosidase small chain/ domain 5 + Glycoside hydrolase, family 2 + Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich + Glycoside hydrolase, family 2, TIM barrel + Glycosyl hydrolases family 2, sugar binding domain + Galactose-binding domain-like + Galactose mutarotase-like domain + Glycoside hydrolase, catalytic domain + Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain + Glycoside hydrolase-type carbohydrate-binding, subgroup + Glycoside hydrolase superfamily + Glycoside hydrolase, family 2, conserved site + Glycoside hydrolase, family 2, active site + Beta-galactosidase, domain 4 Bcin02g08970 552 CAZy : GH71FCW //SignalP-noTM Glycoside hydrolase, family 71 Bcin02g08980 520 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g08990 303 Ceramidase Bcin02g09000 398 BTB/POZ-like + BTB/POZ fold Bcin02g09010 96 Effector(V1) Bcin02g09020 204 Bcin02g09030 574 FAD linked oxidase, N-terminal + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin02g09040 522 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin02g09050 337 NADP-dependent oxidoreductase domain Bcin02g09060 1129 Domain of unknown function DUF221 + Protein of unknown function DUF3779, phosphate metabolism + Domain of unknown function DUF4463 + Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain Bcin02g09070 436 Protease Carboxylesterase, type B + Alpha/Beta hydrolase fold Bcin02g09080 678 Bcin02g09090 630 Bcin02g09100 187 Effector(V2)|Effector(V1) Bcin02g09110 372 Bcin02g09120 373 Bcin02g09130 336 "Bcpml1, similar to yeast PML1, Subunit of the RES complex; RES complex is required for nuclear retention of unspliced pre-mRNAs; acts in the same pathway as Pml39p and Mlp1p [Source:SGD;Acc:S000004006]" Bcin02g09140 1560 Domain of unknown function DUF676, lipase-like + Alpha/Beta hydrolase fold + NB-ARC + P-loop containing nucleoside triphosphate hydrolase Bcin02g09160 663 VHS + GAT domain + Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain + Clathrin adaptor, gamma-adaptin, appendage + ENTH/VHS + Coatomer/clathrin adaptor appendage, Ig-like subdomain Bcin02g09170 399 "Bctsr3, similar to yeast TSR3, Protein required for 20S pre-rRNA processing; involved in processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000005532]" Bcin02g09180 791 "Bcnop9, similar to yeast NOP9, Essential subunit of U3-containing 90S preribosome; involved in production of 18S rRNA and assembly of small ribosomal subunit; also part of pre-40S ribosome and required for its export into cytoplasm; binds RNA and contains pumilio domain [Source:SGD;Acc:S000003547]" Bcin02g09190 520 Pyridoxal phosphate-dependent decarboxylase + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin02g09200 1145 "Bcifm1, similar to yeast IFM1, Mitochondrial translation initiation factor 2 [Source:SGD;Acc:S000005383]" Bcin02g09210 352 Bcin02g09220 118 Effector(V2)|Effector(V1) Bcin02g09230 345 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + NAD(P)-binding domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Bcin02g09240 59 SignalP-noTM Bcin02g09250 326 AMMECR1 domain + AMMECR1 + AMMECR1, N-terminal Bcin02g09260 299 Small GTPase superfamily + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin02g09270 1012 PAZ domain + Piwi domain + Ribonuclease H-like domain + Domain of unknown function DUF1785 + Argonaute linker 2 domain + Protein argonaute, Mid domain + Protein argonaute, N-terminal Bcin02g09280 1009 "Bcrna14, similar to yeast RNA14, Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; bridges interaction between Rna15p and Hrp1p in the CF I complex; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; required for gene looping and maintenance of genome stability; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000004665]" Bcin02g09290 280 "Bcasf1, similar to yeast ASF1, Nucleosome assembly factor; involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003651]" Bcin02g09300 987 WD40 repeat + Quinoprotein amine dehydrogenase, beta chain-like + Lethal giant larvae (Lgl)-like, C-terminal domain + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin02g09310 133 Effector(V1) Bcin02g09320 242 Casein kinase substrate, phosphoprotein PP28 Bcin02g09330 251 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger, C2H2-like Bcin02g09340 1029 Zn2/Cys6 transcription factor + Cys2His2 RNA recognition motif domain + Zn(2)-C6 fungal-type DNA-binding domain + Zinc finger, C2H2 + Nucleotide-binding alpha-beta plait domain Bcin02g09350 778 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB Bcin02g09360 119 Bcin02g09370 479 C2 domain + Synaptotagmin-like mitochondrial-lipid-binding domain Bcin02g09380 400 SignalP-noTM Six-bladed beta-propeller, TolB-like + SMP-30/Gluconolactonase/LRE-like region Bcin02g09390 391 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin02g09400 293 RTA-like protein Bcin02g09410 229 Bcin03g00005 144 Effector(V2)|Effector(V1) Hemolysin, aegerolysin type Bcin03g00010 489 Bcin03g00020 225 Effector(V2)|Effector(V1) Bcin03g00030 331 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin03g00040 308 Protein of unknown function DUF3425 Bcin03g00050 469 Cys2His2 transcription factor "Bcrex3, similar to yeast REX3, RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases [Source:SGD;Acc:S000004097]" Bcin03g00060 462 Bcin03g00070 453 Tetracycline resistance protein, TetA/multidrug resistance protein MdtG + Major facilitator superfamily + Major facilitator superfamily domain Bcin03g00080 300 Taurine catabolism dioxygenase TauD/TfdA Bcin03g00090 502 Bcin03g00100 136 "Bcgim3, similar to yeast GIM3, Subunit of the heterohexameric cochaperone prefoldin complex; prefoldin binds specifically to cytosolic chaperonin and transfers target proteins to it; prefoldin complex also localizes to chromatin of actively transcribed genes in the nucleus and facilitates transcriptional elongation [Source:SGD;Acc:S000005097]" Bcin03g00110 574 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g00120 440 Bcin03g00130 369 Oxoglutarate/iron-dependent dioxygenase + Isopenicillin N synthase-like Bcin03g00140 1938 Reverse transcriptase domain + HMG-I/HMG-Y, DNA-binding, conserved site + Integrase, catalytic core + Zinc finger, CCHC-type + Ribonuclease H-like domain + Chromo domain-like Bcin03g00150 333 "Bcdoc1, similar to yeast DOC1, Processivity factor; required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition; involved in cyclin proteolysis; contains a conserved DOC1 homology domain [Source:SGD;Acc:S000003209]" Bcin03g00160 86 Effector(V1) Bcin03g00170 107 Effector(V2) Bcin03g00180 335 SignalP-noTM Mannose-6-phosphate receptor binding domain + Autophagy-related protein 27 Bcin03g00190 303 Bcin03g00200 521 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g00210 1052 AMP-dependent synthetase/ligase + Phosphopantetheine attachment site + Acyl carrier protein-like + Male sterility, NAD-binding + NAD(P)-binding domain + Polyketide synthase, phosphopantetheine-binding domain + AMP-binding, conserved site Bcin03g00220 773 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin03g00230 381 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain + Mandelate racemase/muconate lactonizing enzyme, C-terminal + Mandelate racemase/muconate lactonizing enzyme, conserved site + Enolase N-terminal domain-like + Enolase C-terminal domain-like Bcin03g00240 324 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin03g00250 327 DapA-like + Aldolase-type TIM barrel + Schiff base-forming aldolase, conserved site Bcin03g00260 122 Effector(V2)|Effector(V1) Bcin03g00270 109 Effector(V1) Bcin03g00280 384 CAZy : PL1PCW pectin//SignalP-noTM//Early secretome Pectate lyase/Amb allergen + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin03g00290 692 SignalP-noTM//Early secretome Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin03g00300 818 "Bcdbp6, similar to yeast DBP6, Essential protein involved in ribosome biogenesis; putative ATP-dependent RNA helicase of the DEAD-box protein family [Source:SGD;Acc:S000005321]" Bcin03g00310 490 CAZy : GT4 "Bcspt14, similar to yeast SPT14, UDP-glycosyltransferase subunit of the GPI-GnT complex; UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins [Source:SGD;Acc:S000006096]" Bcin03g00320 427 SignalP-noTM Bcprd5, Peroxidase Bcin03g00330 550 Heterokaryon incompatibility Bcin03g00340 124 SignalP-noTM Bcin03g00350 279 Bcin03g00360 299 Protein of unknown function DUF3431 Bcin03g00370 319 Bcin03g00380 507 SignalP-noTM//Early secretome FAD linked oxidase, N-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin03g00390 625 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g00400 249 GNAT domain + Acyl-CoA N-acyltransferase Bcin03g00410 558 ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin03g00420 268 Acyl-CoA N-acyltransferase Bcin03g00430 1035 "Bclhs1, similar to yeast LHS1, Molecular chaperone of the endoplasmic reticulum lumen; involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway [Source:SGD;Acc:S000001556]" Bcin03g00440 618 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin03g00450 795 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin03g00460 1385 Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily + GAF domain-like Bcin03g00480 227 yes CAZy : GH11PCW hemicellulose//SignalP-noTM Bcxyn11A, Xylanase Bcin03g00490 984 Bcin03g00500 137 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Bcspl1, Snod-prot-like, induced by ethylene, cerato-platanin gene Bcin03g00510 262 Bcin03g00520 471 Bcin03g00530 436 Bcin03g00540 513 CAZy : GH13Energy Glycosyl hydrolase, family 13, catalytic domain + Alpha-amylase, thermostable + Glycosyl hydrolase, family 13, all-beta + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin03g00550 1094 Bcin03g00560 248 Effector(V2) Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site + Cyclophilin-type peptidyl-prolyl cis-trans isomerase + Cyclophilin-like domain Bcin03g00570 169 SignalP-TM//Early secretome Cell wall galactomannoprotein Bcin03g00580 277 Bcin03g00590 213 Effector(V2)|Effector(V1) "Bcrps5, similar to yeast RPS5, Protein component of the small (40S) ribosomal subunit; least basic of non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; homologous to mammalian ribosomal protein S5 and bacterial S7 [Source:SGD;Acc:S000003884]" Bcin03g00600 219 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin03g00610 757 "Bcsda1, similar to yeast SDA1, Protein required for actin organization and passage through Start; highly conserved nuclear protein; required for actin cytoskeleton organization; plays a critical role in G1 events; binds Nap1p; involved in 60S ribosome biogenesis [Source:SGD;Acc:S000003477]" Bcin03g00620 1005 Tetratricopeptide-like helical domain + P-loop containing nucleoside triphosphate hydrolase Bcin03g00630 210 Effector(V1) Bcin03g00640 666 CAZy : AA3 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin03g00650 492 SignalP-TM Indoleamine 2,3-dioxygenase Bcin03g00660 304 S-adenosyl-L-methionine-dependent methyltransferase Bcin03g00670 526 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g00680 210 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2) Bcin03g00690 227 Effector(V2) Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin03g00700 300 NmrA-like domain + NAD(P)-binding domain Bcin03g00710 773 Zn2/Cys6 transcription factor + Cys2His2 + Fungal_trans Zn(2)-C6 fungal-type DNA-binding domain + Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin03g00720 117 Effector(V2)|Effector(V1) Bcin03g00730 254 Bcin03g00740 482 Bcin03g00750 590 Bzip transcription factor BczipA, Bzip transcription factor Bcin03g00760 900 Bcin03g00770 918 U3 small nucleolar RNA-associated protein 8 Bcin03g00780 1219 AAA+ ATPase domain + ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin03g00790 97 Effector(V2)|Effector(V1) Ribosomal protein S25 Bcin03g00800 275 Cytochrome b5-like heme/steroid binding domain Bcin03g00810 137 Effector(V2)|Effector(V1) Bcin03g00820 558 Amidase + Amidase, conserved site + Amidase signature domain Bcin03g00830 164 Bcin03g00840 177 Effector(V2)|Effector(V1) Bcin03g00850 924 Bcin03g00860 355 "Bcaah1, similar to yeast AAH1, Adenine deaminase (adenine aminohydrolase); converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome [Source:SGD;Acc:S000005085]" Bcin03g00870 870 Zn2/Cys6 + fungal trans transcription factor Bczfr1, Zn2/Cys6 transcription factor Bcin03g00880 238 Centromere protein X Bcin03g00890 272 SignalP-noTM Cupredoxin Bcin03g00900 312 TRAM/LAG1/CLN8 homology domain Bcin03g00910 324 AdipoR/Haemolysin-III-related Bcin03g00920 597 SignalP-TM Bcin03g00930 697 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g00940 853 Zn2/Cys6 + fungal trans transcription factor//Signaling pathway Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin03g00950 1150 Phosphoribosyltransferase domain + Higher eukaryotic phosphomevalonate kinase + FAD linked oxidase, N-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 + Phosphoribosyltransferase-like + S-adenosyl-L-methionine-dependent methyltransferase Bcin03g00960 260 GTP cyclohydrolase I + GTP cyclohydrolase I, conserved site + GTP cyclohydrolase I domain Bcin03g00970 111 Bcin03g00980 132 Bcin03g00990 520 Bcin03g01000 581 Early secretome Bcin03g01010 313 Transporter Mitochondrial carrier protein + Adenine nucleotide translocator 1 + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin03g01020 117 Bcin03g01030 322 Transporter "Bcmir1, similar to yeast MIR1, Mitochondrial phosphate carrier; imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2p under normal conditions; phosphorylated [Source:SGD;Acc:S000003838]" Bcin03g01040 516 Pyridoxal phosphate-dependent decarboxylase + Glutamate decarboxylase + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin03g01050 1068 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin03g01060 466 Bcin03g01070 531 Transporter General substrate transporter + Major facilitator superfamily domain + Sugar/inositol transporter Bcin03g01080 584 SignalP-noTM Bcin03g01090 224 Effector(V1) "Bcnop16, similar to yeast NOP16, Constituent of 66S pre-ribosomal particles; involved in 60S ribosomal subunit biogenesis [Source:SGD;Acc:S000000804]" Bcin03g01100 892 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin03g01110 163 Effector(V2) Bcin03g01120 172 Bcin03g01130 558 Aldehyde dehydrogenase domain + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain + Aldehyde dehydrogenase, C-terminal + Aldehyde dehydrogenase, glutamic acid active site Bcin03g01140 565 Bzip transcription factor Basic-leucine zipper domain Bcin03g01150 304 Senescence marker protein-30 (SMP-30) + Six-bladed beta-propeller, TolB-like + SMP-30/Gluconolactonase/LRE-like region Bcin03g01160 298 Bcin03g01170 279 Bcin03g01180 176 IQ motif, EF-hand binding site Bcin03g01190 239 Effector(V2)|Effector(V1) Bcin03g01200 633 AAA+ ATPase domain + ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin03g01210 1576 P-loop containing nucleoside triphosphate hydrolase Bcin03g01220 81 Effector(V1) Bcin03g01230 193 CAZy : CE5PCW hemicellulose Cutinase + Alpha/Beta hydrolase fold Bcin03g01240 108 Bcin03g01250 162 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin03g01260 212 Effector(V2)|Effector(V1) D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain + NAD(P)-binding domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Bcin03g01270 604 Alpha/Beta hydrolase fold Bcin03g01280 1263 Protein of unknown function DUF3659 Bcin03g01290 848 Bcin03g01300 247 Bcin03g01310 205 SignalP-noTM Bcin03g01320 154 Effector(V1) Bcin03g01330 133 Bcin03g01340 264 Bcin03g01350 159 Effector(V2)|Effector(V1) Bcin03g01360 146 Effector(V1) Bcin03g01370 131 Effector(V1) Bcin03g01380 117 Effector(V1) Bcin03g01390 143 Effector(V1) Bcin03g01400 193 Bcin03g01410 295 Bcin03g01420 243 Bcin03g01430 133 Effector(V2)|Effector(V1) Bcin03g01440 444 CAZy : CBM1,GH5PCW/FCW //SignalP-noTM Cellulose-binding domain, fungal + Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin03g01450 208 GNAT domain + Acyl-CoA N-acyltransferase Bcin03g01460 210 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2) Bcin03g01470 442 Bcdao7, D-amino acid oxidase Bcin03g01480 254 yes Effector(V2) Bcgpx3, Glutathione peroxidase Bcin03g01490 325 yes Bclga1, 2-keto-3-deoxy-L-galactonate aldolase Bcin03g01500 421 yes Bcgar2, D-galacturonate reductase Bcin03g01510 203 Bcin03g01520 381 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain Bcin03g01530 783 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin03g01540 628 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin03g01550 1111 AMP-dependent synthetase/ligase + Phosphopantetheine attachment site + Acyl carrier protein-like + Male sterility, NAD-binding + NAD(P)-binding domain + AMP-binding, conserved site Bcin03g01560 345 Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin03g01570 1062 AMP-dependent synthetase/ligase + Acyl carrier protein-like + Male sterility, NAD-binding + NAD(P)-binding domain + Polyketide synthase, phosphopantetheine-binding domain + AMP-binding, conserved site Bcin03g01580 523 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, conserved site + Alpha/Beta hydrolase fold Bcin03g01590 240 Effector(V2) Bcin03g01600 266 CAZy : GHnc //SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin03g01610 425 CAZy : GH26PCW hemicellulose Glycoside hydrolase, family 26 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Endoglucanase H/Glycosyl hydrolase family 26 Bcin03g01620 349 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin03g01630 151 Effector(V1) F-box domain Bcin03g01640 190 Effector(V1) Leucine-rich repeat domain, L domain-like Bcin03g01650 156 Effector(V1) Bcin03g01660 360 Bcin03g01670 828 "Bcvps16, similar to yeast VPS16, Subunit of the HOPS and the CORVET complexes; part of the Class C Vps complex essential for membrane docking and fusion at Golgi-to-endosome and endosome-to-vacuole protein transport stages [Source:SGD;Acc:S000005966]" Bcin03g01680 397 CAZy : GH28PCW pectin//SignalP-noTM Bcpg4, Endopolygalacturonase Bcin03g01690 1482 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase + Alpha-factor-transporting ATPase Ste6 Bcin03g01700 578 Protease "Bcmas2, similar to yeast MAS2, Alpha subunit of the mitochondrial processing protease (MPP); essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins [Source:SGD;Acc:S000001066]" Bcin03g01710 709 Forkhead-associated (FHA) domain + Zinc finger, RING-type + SMAD/FHA domain + Zinc finger, RING/FYVE/PHD-type Bcin03g01720 632 yes Signaling pathway Bcptc1, Type 2C Ser/Thr phosphatase (PP2C) Bcin03g01730 228 "Bcdid4, similar to yeast DID4, Class E Vps protein of the ESCRT-III complex; required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis [Source:SGD;Acc:S000001485]" Bcin03g01740 925 "Bcfzo1, similar to yeast FZO1, Mitofusin; integral membrane protein involved in mitochondrial outer membrane tethering and fusion; role in mitochondrial genome maintenance; efficient tethering and degradation of Fzo1p requires an intact N-terminal GTPase domain; targeted for destruction by the ubiquitin ligase SCF-Mdm30p and the cytosolic ubiquitin-proteasome system [Source:SGD;Acc:S000000383]" Bcin03g01750 1023 Na+/H+ antiporter, fungi + Cation/H+ exchanger + Alkali metal cation/H+ antiporter Nha1, C-terminal Bcin03g01760 464 "Bcrit1, similar to yeast RIT1, Initiator methionine 2'-O-ribosyl phosphate transferase; modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA [Source:SGD;Acc:S000004896]" Bcin03g01770 898 Bcin03g01780 194 Effector(V1) Protein of unknown function DUF4202 Bcin03g01790 414 Bcin03g01800 495 Bcin03g01810 108 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin03g01820 217 Effector(V2)|Effector(V1) Ribosomal protein L1 + Ribosomal protein L1, 2-layer alpha/beta-sandwich + Ribosomal protein L1, 3-layer alpha/beta-sandwich + Ribosomal protein L1, conserved site + Ribosomal protein L1-like + Ribosomal protein L1/ribosomal biogenesis protein Bcin03g01830 575 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g01840 639 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin03g01850 298 14-3-3 protein + 14-3-3 domain Bcin03g01860 450 Acyl-CoA dehydrogenase, conserved site + Acyl-CoA oxidase/dehydrogenase, central domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase/oxidase, N-terminal Bcin03g01870 472 Leucine-rich repeat domain, L domain-like Bcin03g01880 529 CAZy : GT22 //SignalP-noTM GPI mannosyltransferase Bcin03g01890 167 "Bcskp1, similar to yeast SKP1, Evolutionarily conserved kinetochore protein; part of multiple protein complexes, including the SCF ubiquitin ligase complex, the CBF3 complex that binds centromeric DNA, and the RAVE complex that regulates assembly of the V-ATPase; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002736]" Bcin03g01900 51 Ribosomal protein L39e + Ribosomal protein L39e domain Bcin03g01910 181 Effector(V1) "Bcarl1, similar to yeast ARL1, Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; role in membrane organization at trans-Golgi network; G protein of the Ras superfamily, similar to ADP-ribosylation factor [Source:SGD;Acc:S000000368]" Bcin03g01920 509 Bccat5, Catalase Bcin03g01930 802 Bcin03g01940 208 SignalP-noTM Bcin03g01950 240 Effector(V1) Protein of unknown function DUF3328 Bcin03g01960 270 Bcin03g01970 265 Protein of unknown function DUF3328 Bcin03g01980 641 Zn2/Cys6 + fungal trans transcription factor//SM cluster PKS17 Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin03g01990 333 SM cluster PKS17 Oxoglutarate/iron-dependent dioxygenase + Non-haem dioxygenase N-terminal domain + Isopenicillin N synthase-like Bcin03g02000 271 SM cluster PKS17 Serine hydrolase FSH + Alpha/Beta hydrolase fold Bcin03g02010 2585 SM cluster PKS17 (KE) Bcpks17, Polyketide synthase Bcin03g02020 377 SM cluster PKS17 "Bcgal80, similar to yeast GAL80, Transcriptional regulator involved in the repression of GAL genes; involved in the repression of GAL genes in the absence of galactose; inhibits transcriptional activation by Gal4p; inhibition relieved by Gal3p or Gal1p binding [Source:SGD;Acc:S000004515]" Bcin03g02030 553 Protease//SignalP-noTM Peptidase S10, serine carboxypeptidase + Alpha/Beta hydrolase fold + Serine carboxypeptidases, histidine active site Bcin03g02040 642 Protease//SignalP-noTM Peptidase S8/S53 domain + Proteinase inhibitor, propeptide + Peptidase S53, propeptide + Sedolisin domain Bcin03g02050 1450 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase + Alpha-factor-transporting ATPase Ste6 Bcin03g02060 297 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin03g02070 622 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin03g02080 567 Flavin monooxygenase FMO + Dimethylaniline monooxygenase, N-oxide-forming + Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin03g02090 423 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g02100 306 Domain of unknown function DUF676, lipase-like + Alpha/Beta hydrolase fold Bcin03g02110 507 SignalP-noTM Cytochrome P450 + Cytochrome P450, E-class, group II + Cytochrome P450, E-class, CYP52 + Cytochrome P450, conserved site Bcin03g02120 1150 NB-ARC + Tetratricopeptide-like helical domain + P-loop containing nucleoside triphosphate hydrolase + Alpha/Beta hydrolase fold Bcin03g02130 695 Bicarbonate transporter, eukaryotic + Bicarbonate transporter, C-terminal Bcin03g02140 697 Alpha/Beta hydrolase fold Bcin03g02150 574 Bcin03g02160 895 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin03g02170 903 Protease Peptidase M41 + AAA+ ATPase domain + ATPase, AAA-type, core + ATPase, AAA-type, conserved site + Peptidase, FtsH + Peptidase M41, FtsH extracellular + P-loop containing nucleoside triphosphate hydrolase Bcin03g02180 160 Bcin03g02190 402 "Bcnab6, similar to yeast NAB6, Putative RNA-binding protein; associates with mRNAs encoding cell wall proteins in high-throughput studies; deletion mutants display increased sensitivity to some cell wall disrupting agents; expression negatively regulated by cAMP [Source:SGD;Acc:S000004585]" Bcin03g02200 548 The Golgi pH Regulator + Golgi pH regulator, conserved domain + Abscisic acid G-protein coupled receptor-like domain Bcin03g02210 423 Uncharacterised protein family UPF0261 Bcin03g02220 279 Effector(V1) TIM-barrel domain, IGPS-like + Aldolase-type TIM barrel + Pyruvate/Phosphoenolpyruvate kinase-like domain Bcin03g02230 503 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA + S-adenosyl-L-methionine-dependent methyltransferase Bcin03g02240 470 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain Bcin03g02250 306 SignalP-TM Bcin03g02260 416 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin03g02270 343 Cys2His2 transcription factor "Bcrts2, similar to yeast RTS2, Basic zinc-finger protein; similar to human and mouse Kin17 proteins which are chromatin-associated proteins involved in UV response and DNA replication [Source:SGD;Acc:S000005603]" Bcin03g02280 121 Effector(V2)|Effector(V1) "Bcspt4, similar to yeast SPT4, Component of the universally conserved Spt4/5 complex (DSIF complex); the complex has multiple roles in concert with RNA polymerases I and II, including regulation of transcription elongation, RNA processing, quality control, and transcription-coupled DNA repair; Spt4p also localizes to kinetochores and heterochromatin and affects chromosome dynamics and silencing; required for transcription through lengthy trinucleotide repeats in ORFs or non-protein coding regions [Source:SGD;Acc:S000003295]" Bcin03g02290 151 Effector(V2) Bcin03g02300 1695 Rap GTPase activating protein domain + Armadillo-type fold + Tuberin-type domain + Tuberin, N-terminal Bcin03g02310 962 "Bccse1, similar to yeast CSE1, Nuclear envelope protein that mediates the nuclear export of Srp1p; Srp1p (importin alpha) is a homolog of metazoan CAS protein; required for accurate chromosome segregation [Source:SGD;Acc:S000003207]" Bcin03g02320 475 Translation initiation factor 3 complex subunit L Bcin03g02330 508 UspA + Rossmann-like alpha/beta/alpha sandwich fold Bcin03g02340 645 Xanthine/uracil/vitamin C permease Bcin03g02350 527 Transporter "Bchom3, similar to yeast HOM3, Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis [Source:SGD;Acc:S000000854]" Bcin03g02360 821 Regulatory Factor X (RFX) transcription factor Bccpcr1, RFX transcription factor Bcin03g02370 162 "Bcyop1, similar to yeast YOP1, Membrane protein that interacts with Yip1p to mediate membrane traffic; interacts with Sey1p to maintain ER morphology; overexpression leads to cell death and accumulation of internal cell membranes; mutants have reduced phosphatidylserine transfer between the ER and mitochondria; forms ER foci upon DNA replication stress [Source:SGD;Acc:S000006232]" Bcin03g02380 674 yes Signaling pathway Bcmid1, Secreted Ca2 channel protein Bcin03g02390 765 Fork head transcription factor "Bchcm1, similar to yeast HCM1, Forkhead transcription factor; drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role; regulates replicative lifespan; ortholog of C. elegans lifespan regulator PHA-4 [Source:SGD;Acc:S000000661]" Bcin03g02400 58 Bcin03g02410 536 "Bcsat4, similar to yeast SAT4, Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion [Source:SGD;Acc:S000000601]" Bcin03g02420 446 Bcin03g02430 148 "Bcrpc19, similar to yeast RPC19, RNA polymerase subunit AC19; common to RNA polymerases I and III [Source:SGD;Acc:S000005057]" Bcin03g02440 123 NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6 Bcin03g02450 147 Effector(V2)|Effector(V1) "Bcbud31, similar to yeast BUD31, Component of the SF3b subcomplex of the U2 snRNP; increases efficiency of first and second step pre-mRNA splicing; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; facilitates passage through G1/S Start, but is not required for G2/M transition or exit from mitosis [Source:SGD;Acc:S000000659]" Bcin03g02460 730 Bccmk3, Ca2?dependent kinase Bcin03g02470 177 Effector(V2)|Effector(V1) "Bcbet5, similar to yeast BET5, Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factors for the GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII) [Source:SGD;Acc:S000004542]" Bcin03g02480 517 "Bcpex3, similar to yeast PEX3, Peroxisomal membrane protein (PMP); required for proper localization and stability of PMPs; anchors peroxisome retention factor Inp1p at the peroxisomal membrane; interacts with Pex19p [Source:SGD;Acc:S000002737]" Bcin03g02490 193 Autophagy-related protein 1010 Bcin03g02500 280 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger, C2H2-like Bcin03g02510 829 Tetratricopeptide-like helical domain + DNA/RNA-binding domain, Est1-type + Telomerase activating protein Est1 Bcin03g02520 348 "Bcado1, similar to yeast ADO1, Adenosine kinase; required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle [Source:SGD;Acc:S000003866]" Bcin03g02530 254 Ribosomal protein L2 + Translation protein SH3-like domain + Nucleic acid-binding, OB-fold + Ribosomal protein L2 domain 2 + Ribosomal protein L2, domain 3 + Ribosomal Proteins L2, RNA binding domain + Ribosomal protein L2, C-terminal + Ribosomal protein L2, conserved site Bcin03g02540 593 Effector(V2)|Effector(V1) WHIM1 domain Bcin03g02550 187 Effector(V1) Protein of unknown function DUF1770, fungi Bcin03g02560 221 Effector(V2) Bcin03g02570 172 Marvel domain Bcin03g02580 306 Urease accessory protein UreF Bcin03g02590 393 "Bccwc2, similar to yeast CWC2, Member of the NineTeen Complex (NTC); this complex contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; binds directly to U6 snRNA; similar to S. pombe Cwf2 [Source:SGD;Acc:S000002368]" Bcin03g02600 349 SignalP-TM Bcin03g02610 134 Effector(V1) Bcin03g02620 972 "Bcpep3, similar to yeast PEP3, Component of CORVET membrane tethering complex; vacuolar peripheral membrane protein that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins, required for vacuolar biogenesis [Source:SGD;Acc:S000004138]" Bcin03g02630 957 yes Bcste11, Mitogen-activated protein kinase (MAPK) : MAPKKK Bcin03g02640 312 Butirosin biosynthesis, BtrG-like + Gamma-glutamylcyclotransferase Bcin03g02650 1275 Pleckstrin homology domain + Leucine-rich repeat domain, L domain-like Bcin03g02660 266 MaoC-like domain + HotDog domain Bcin03g02670 331 "Bcpha2, similar to yeast PHA2, Prephenate dehydratase; catalyzes the conversion of prephanate to phenylpyruvate, which is a step in the phenylalanine biosynthesis pathway [Source:SGD;Acc:S000005260]" Bcin03g02680 435 "Bcsup45, similar to yeast SUP45, Polypeptide release factor (eRF1) in translation termination; mutant form acts as a recessive omnipotent suppressor; methylated by Mtq2p-Trm112p in ternary complex eRF1-eRF3-GTP; mutation of methylation site confers resistance to zymocin; has a role in cytokinesis through interaction with Mlc1p [Source:SGD;Acc:S000000347]" Bcin03g02690 154 Effector(V2)|Effector(V1) Bcin03g02700 262 Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin03g02710 502 CAZy : GH27PCW hemicellulose//SignalP-noTM//Early secretome Glycoside hydrolase, clan GH-D + Glycoside hydrolase, family 27 + Glycoside hydrolase, melibiase + Glycosyl hydrolase, family 13, all-beta + Aldolase-type TIM barrel + Glycoside hydrolase superfamily Bcin03g02720 538 "Bcpgs1, similar to yeast PGS1, Phosphatidylglycerolphosphate synthase; catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis [Source:SGD;Acc:S000000510]" Bcin03g02730 136 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 Bcin03g02740 475 Protease Arginine biosynthesis protein ArgJ + ArgJ-like domain Bcin03g02750 1599 Effector(V1) RWD domain + Ubiquitin-conjugating enzyme/RWD-like + Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Serine/threonine-protein kinase, GCN2 + Protein kinase, ATP binding site + Histidyl tRNA synthetase-related domain Bcin03g02760 482 yes Protease//SignalP-noTM Bcap4, Aspartic proteinase Bcin03g02770 167 V-ATPase proteolipid subunit + V-ATPase proteolipid subunit C-like domain + V-ATPase proteolipid subunit C, eukaryotic Bcin03g02780 1684 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin03g02790 476 "Bcsec61, similar to yeast SEC61, Conserved ER protein translocation channel; essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms channel for SRP-dependent protein import; with Sec63 complex allows SRP-independent protein import into ER; involved in posttranslational soluble protein import into the ER, ERAD of soluble substrates, and misfolded soluble protein export from the ER [Source:SGD;Acc:S000004370]" Bcin03g02800 1121 Transporter P-type ATPase + Cation-transporting P-type ATPase, N-terminal + Cation-transporting P-type ATPase, C-terminal + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, transmembrane domain + P-type ATPase, cytoplasmic domain N Bcin03g02810 484 Cys2His2 transcription factor "Bcmod5, similar to yeast MOD5, Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase; required for biosynthesis of isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; also has a role in tRNA gene-mediated silencing; gene encodes two isozymic forms; converts to a prion form, prion conversion contributes to azole antifungal resistance by upregulating ergosterol biosynthesis; homolog of human TRIT1, a mutation in which is associated with severe combined respiratory chain defects [Source:SGD;Acc:S000005800]" Bcin03g02820 597 "Bcorc2, similar to yeast ORC2, Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; interacts with Spp1p and with trimethylated histone H3; phosphorylated by Cdc28p [Source:SGD;Acc:S000000264]" Bcin03g02830 726 Spindle-body formation-associated protein Bcin03g02840 231 "Bccdc34, similar to yeast CDC34, Ubiquitin-conjugating enzyme (E2); catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002461]" Bcin03g02850 840 Ubiquitin interacting motif Bcin03g02860 380 "Bcsis1, similar to yeast SIS1, Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; shuttles between cytosol and nucleus; mediates delivery of misfolded proteins into the nucleus for degradation; involved in proteasomal degradation of misfolded cytosolic proteins; protein abundance increases in response to DNA replication stress; polyQ aggregates sequester Sis1p and interfere with clearance of misfolded proteins; similar to bacterial DnaJ proteins and mammalian DnaJB1 [Source:SGD;Acc:S000004952]" Bcin03g02870 340 Oxoglutarate/iron-dependent dioxygenase + Non-haem dioxygenase N-terminal domain + Isopenicillin N synthase-like Bcin03g02880 420 Argininosuccinate synthase + Rossmann-like alpha/beta/alpha sandwich fold + Argininosuccinate synthetase, catalytic/multimerisation domain body Bcin03g02890 309 Translation protein, beta-barrel domain + Threonyl/alanyl tRNA synthetase, SAD + Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain + Alanyl-tRNA synthetase, class IIc, N-terminal + Alanyl-tRNA synthetase, class IIc, core domain Bcin03g02900 342 Carbon-nitrogen hydrolase Bcin03g02910 447 Major facilitator superfamily + Major facilitator superfamily domain Bcin03g02920 641 Bcin03g02930 852 yes Signaling pathway Bccla4, Mitogen-activated protein kinase (MAPK) : p21-activated kinase (PAK) Bcin03g02940 710 Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain + Glycyl-tRNA synthetase + Anticodon-binding + Aminoacyl-tRNA synthetase, class II + Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 Bcin03g02950 414 "Bcrpf1, similar to yeast RPF1, Protein involved in assembly and export of the large ribosomal subunit; nucleolar protein; constituent of 66S pre-ribosomal particles; contains a sigma(70)-like motif, which is thought to bind RNA [Source:SGD;Acc:S000001130]" Bcin03g02960 563 Major facilitator superfamily + Major facilitator superfamily domain Bcin03g02970 484 CAZy : CBM18,CE4,CBM18,CBM18FCW //SignalP-noTM//Early secretome Bccda3, Chitin deacetylase Bcin03g02980 219 Effector(V2)|Effector(V1) "Bctae1, similar to yeast TAE1, AdoMet-dependent proline methyltransferase; catalyzes the dimethylation of ribosomal proteins Rpl12 and Rps25 at N-terminal proline residues; has a role in protein synthesis; fusion protein localizes to the cytoplasm [Source:SGD;Acc:S000000465]" Bcin03g02990 107 Effector(V1) Bcin03g03000 275 Bcin03g03010 339 Bcin03g03020 454 Bcin03g03030 401 Bcin03g03040 428 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin03g03050 372 Bcin03g03060 436 yes Bcdh, UDP-glucose-4,6-dehydratase Bcin03g03070 438 S-adenosyl-L-methionine-dependent methyltransferase Bcin03g03080 210 Effector(V1) Bcin03g03090 330 FR47-like + Acyl-CoA N-acyltransferase Bcin03g03100 1014 SH3 domain + Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site + Zinc finger, C3HC4 RING-type Bcin03g03110 675 Bcin03g03120 661 THO complex, subunit THOC1 Bcin03g03130 1441 CWF11 family + P-loop containing nucleoside triphosphate hydrolase + Intron-binding protein aquarius, N-terminal Bcin03g03140 670 Homeobox transcription factor Bchox6, Homeobox transcription factor Bcin03g03150 318 3-hydroxyacyl-CoA dehydrogenase, C-terminal + 3-hydroxyacyl-CoA dehydrogenase, NAD binding + 3-hydroxyacyl-CoA dehydrogenase, conserved site + 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + NAD(P)-binding domain + 3-hydroxyacyl-CoA dehydrogenase Bcin03g03160 1161 "Bctof1, similar to yeast TOF1, Subunit of a replication-pausing checkpoint complex; Tof1p-Mrc1p-Csm3p acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005217]" Bcin03g03170 385 Effector(V2) Ankyrin repeat + Ankyrin repeat-containing domain Bcin03g03180 246 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin03g03190 205 Bcin03g03200 436 Bcin03g03210 99 S-adenosyl-L-methionine-dependent methyltransferase Bcin03g03220 477 CAZy : CBM18,GH18FCW Chitin-binding, type 1 + Glycoside hydrolase, family 18, catalytic domain + Chitinase II + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Chitin-binding, type 1, conserved site + Chitinase insertion domain Bcin03g03230 647 "Bcsas10, similar to yeast SAS10, Subunit of U3-containing Small Subunit (SSU) processome complex; involved in production of 18S rRNA and assembly of small ribosomal subunit; disrupts silencing when overproduced; mutant has increased aneuploidy tolerance; essential gene [Source:SGD;Acc:S000002312]" Bcin03g03240 1017 Mediator complex, subunit Med5, fungi Bcin03g03250 255 Effector(V2) Bcin03g03260 106 Bcin03g03270 496 FMN-dependent dehydrogenase + Cytochrome b5-like heme/steroid binding domain + Alpha-hydroxy acid dehydrogenase, FMN-dependent + Aldolase-type TIM barrel Bcin03g03280 421 Effector(V2)|Effector(V1) FMN-dependent dehydrogenase + Alpha-hydroxy acid dehydrogenase, FMN-dependent + Aldolase-type TIM barrel Bcin03g03290 357 "Bcmtq1, similar to yeast MTQ1, S-adenosylmethionine-dependent methyltransferase; methylates translational release factor Mrf1p; similar to E.coli PrmC; is not an essential gene [Source:SGD;Acc:S000005007]" Bcin03g03300 441 Protease//SignalP-noTM Bcap7, Aspartic proteinase Bcin03g03310 607 p53-like transcription factor, DNA-binding + NDT80 DNA-binding domain Bcin03g03320 281 Protein of unknown function DUF2011 Bcin03g03330 618 Amino acid/polyamine transporter I Bcin03g03340 1007 "Bcnam2, similar to yeast NAM2, Mitochondrial leucyl-tRNA synthetase; also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance [Source:SGD;Acc:S000004374]" Bcin03g03350 344 "Bcmtg1, similar to yeast MTG1, Putative GTPase peripheral to the mitochondrial inner membrane; essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals [Source:SGD;Acc:S000004703]" Bcin03g03360 323 yes Early secretome BcTAL, Transaldolase Bcin03g03370 325 Bcin03g03380 939 Tudor domain + Staphylococcal nuclease (SNase-like), OB-fold + RNA-induced silencing complex, nuclease component Tudor-SN Bcin03g03390 154 yes Effector(V2)|Effector(V1)//Early secretome Bcsod1, Superoxide dismutase Bcin03g03400 808 Bcin03g03410 2462 Bcin03g03420 1781 Dbl homology (DH) domain + Citron-like + Pleckstrin homology domain + Pleckstrin homology-like domain Bcin03g03430 703 Bcin03g03440 246 HAD hydrolase, subfamily IA + HAD-like domain Bcin03g03450 270 Bcin03g03460 546 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g03470 187 SignalP-noTM Fucose-specific lectin Bcin03g03480 388 CAZy : CBM1,GH10PCW hemicellulose//SignalP-noTM//Early secretome BcXyn10A, Xylanase of family GH10 (Garcia et al., 2017) Bcin03g03490 1283 Bcin03g03500 396 Actin cortical patch SUR7/pH-response regulator PalI Bcin03g03510 134 Effector(V2)|Effector(V1) Bcin03g03520 123 Effector(V1) Bcin03g03530 721 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin03g03540 660 SignalP-noTM Bcin03g03550 732 Transketolase, N-terminal + Transketolase-like, pyrimidine-binding domain + Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II + Transketolase binding site + Thiamin diphosphate-binding fold + Transketolase family + Transketolase, C-terminal domain Bcin03g03560 283 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin03g03570 141 Effector(V2)|Effector(V1) DhaL domain Bcin03g03580 69 Effector(V2)|Effector(V1) Dak kinase Bcin03g03590 518 Transporter Sugar/inositol transporter + General substrate transporter + Major facilitator superfamily domain Bcin03g03600 739 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin03g03610 815 CAZy : GH92FCW Alpha-1,2-mannosidase, putative + Six-hairpin glycosidase-like + Glycosyl hydrolase family 92 + Glycoside hydrolase-type carbohydrate-binding, subgroup Bcin03g03620 149 Effector(V2)|Effector(V1) Ribosomal protein S19e + Winged helix-turn-helix DNA-binding domain + Ribosomal protein S19e, conserved site Bcin03g03630 248 yes CAZy : GH12PCW cellulose//SignalP-noTM//Early secretome BcXYG1, secreted Xyloglucanase 1 Bcin03g03640 942 Transcription factor Spt20 Bcin03g03650 233 Protein of unknown function DUF3128 Bcin03g03660 857 "Bcyme2, similar to yeast YME2, Integral inner mitochondrial membrane protein; role in maintaining mitochondrial nucleoid structure and number; mutants exhibit an increased rate of mitochondrial DNA escape; shows some sequence similarity to exonucleases [Source:SGD;Acc:S000004917]" Bcin03g03670 234 SignalP-noTM//Effector(V2)|Effector(V1) Bcin03g03680 794 Heterokaryon incompatibility + P-loop containing nucleoside triphosphate hydrolase Bcin03g03690 87 Effector(V1) Bcin03g03700 161 Effector(V1) Bcin03g03710 504 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g03720 1280 Zinc finger, CCCH-type + Putative zinc-finger domain Bcin03g03730 2404 IQ motif, EF-hand binding site + Myosin head, motor domain + Myosin tail + Myosin, N-terminal, SH3-like + Myosin-like IQ motif-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin03g03740 415 F-box domain Bcin03g03750 598 CAZy : GT2 Nucleotide-diphospho-sugar transferases Bcin03g03760 821 Bcin03g03770 282 Bcin03g03780 606 Zinc finger, RING-type + Zinc finger, C6HC-type + Zinc finger, RING/FYVE/PHD-type + E3 ubiquitin ligase RBR family Bcin03g03790 561 Ubiquitin 3 binding protein But2, C-terminal Bcin03g03800 292 Phosphoribosyltransferase domain + Phosphoribosyltransferase-like Bcin03g03810 364 SignalP-noTM Bcin03g03820 486 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site Bcin03g03830 348 yes CAZy : CE8PCW pectin//SignalP-noTM//Early secretome Bcpme2, Pectin methyl esterase Bcin03g03840 719 CAZy : GH17FCW Glycoside hydrolase, family 17 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin03g03850 194 Effector(V2)|Effector(V1) Isochorismatase-like Bcin03g03860 268 Sensitivity To Red Light Reduced-like, SRR1 Bcin03g03870 232 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin03g03880 772 "Bcdoa1, similar to yeast DOA1, WD repeat protein required for ubiquitin-mediated protein degradation; forms a complex with Cdc48p; plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase; facilitates N-terminus-dependent proteolysis of centromeric histone H3 (Cse4p) for faithful chromosome segregation; protein increases in abundance and relocalizes from nucleus to nuclear periphery upon DNA replication stress [Source:SGD;Acc:S000001696]" Bcin03g03890 351 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin03g03900 883 Formin, GTPase-binding domain + Armadillo-type fold Bcin03g03910 379 "Bcapd1, similar to yeast APD1, Protein of unknown function; required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus [Source:SGD;Acc:S000000355]" Bcin03g03920 369 Nucleic acid-binding, OB-fold Bcin03g03930 306 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site Bcin03g03940 427 Thiolase + Thiolase-like + Thiolase, active site + Thiolase, conserved site + Thiolase, N-terminal + Thiolase, C-terminal Bcin03g03950 161 Bcin03g03960 372 F-box domain Bcin03g03970 175 Effector(V2)|Effector(V1) Bcin03g03980 180 Effector(V1) Bcin03g03990 540 SignalP-noTM Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin03g04000 198 Effector(V1) Bcin03g04010 424 yes CAZy : GH5PCW/FCW //SignalP-noTM Bccel5A, Endo-beta-1,4-glucanaseprecursor Bcin03g04020 489 Bcin03g04030 304 SM cluster STC6//SignalP-noTM Bcin03g04040 465 SM cluster STC6 Bcin03g04050 149 SM cluster STC6//Effector(V2)|Effector(V1) Homocysteine S-methyltransferase Bcin03g04060 624 SM cluster STC6 NRAMP family Bcin03g04070 640 Transcription initiation factor TFIID component TAF4 Bcin03g04080 828 "Bcysh1, similar to yeast YSH1, Putative endoribonuclease; subunit of the mRNA cleavage and polyadenylation specificity complex; required for 3' processing, splicing, and transcriptional termination of mRNAs and snoRNAs; protein abundance increases in response to DNA replication stress; YSH1 has a paralog, SYC1, that arose from the whole genome duplication [Source:SGD;Acc:S000004267]" Bcin03g04090 582 Carbohydrate kinase, FGGY + Glycerol kinase + Carbohydrate kinase, FGGY, conserved site + Carbohydrate kinase, FGGY, N-terminal + Carbohydrate kinase, FGGY, C-terminal Bcin03g04100 795 SignalP-noTM Heterokaryon incompatibility Het-C Bcin03g04110 390 "Bcscs7, similar to yeast SCS7, Sphingolipid alpha-hydroxylase; functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth [Source:SGD;Acc:S000004885]" Bcin03g04120 570 RNA recognition motif domain + RNA recognition motif domain, eukaryote + Splicing factor, RBM39-like + Nucleotide-binding alpha-beta plait domain + Splicing factor RBM39, linker Bcin03g04130 1200 "Bcpet127, similar to yeast PET127, Protein with a role in 5'-end processing of mitochondrial RNAs; located in the mitochondrial membrane [Source:SGD;Acc:S000005543]" Bcin03g04140 781 Tetratricopeptide-like helical domain + Cohesin loading factor Bcin03g04150 423 Protease Alpha/beta hydrolase fold-1 + AB-hydrolase ABHD1/2/3 + Alpha/Beta hydrolase fold Bcin03g04160 200 Bcin03g04170 224 Effector(V2)|Effector(V1) "Bchis3, similar to yeast HIS3, Imidazoleglycerol-phosphate dehydratase; catalyzes the sixth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control via Gcn4p [Source:SGD;Acc:S000005728]" Bcin03g04180 114 Effector(V2)|Effector(V1) Bcin03g04190 355 "Bcrfc4, similar to yeast RFC4, Subunit of heteropentameric Replication factor C (RF-C); which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005454]" Bcin03g04200 305 Ankyrin repeat + Ankyrin repeat-containing domain Bcin03g04210 468 Major facilitator superfamily + Major facilitator superfamily domain Bcin03g04220 326 CAZy : GT32 Glycosyltransferase, DXD sugar-binding motif + Nucleotide-diphospho-sugar transferases Bcin03g04230 423 "Bcmmm1, similar to yeast MMM1, ER integral membrane protein, ERMES complex subunit; ERMES links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth; required for mitophagy; ERMES complex is often co-localized with peroxisomes and with concentrated areas of pyruvate dehydrogenase [Source:SGD;Acc:S000003929]" Bcin03g04240 392 GDP-fucose transporter Bcin03g04250 205 PhLP3, Phosducin-like protein (subgroup III) Bcin03g04260 334 Protease "Bcrce1, similar to yeast RCE1, Type II CAAX prenyl protease; involved in the proteolysis and maturation of Ras and the a-factor mating pheromone [Source:SGD;Acc:S000004887]" Bcin03g04270 1056 Bcin03g04280 542 "Bcale1, similar to yeast ALE1, Broad-specificity lysophospholipid acyltransferase; part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids [Source:SGD;Acc:S000005701]" Bcin03g04290 593 "Bcvps45, similar to yeast VPS45, Protein of the Sec1p/Munc-18 family; essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment [Source:SGD;Acc:S000003063]" Bcin03g04300 534 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin03g04310 677 SignalP-noTM Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin03g04320 495 Transporter Tetracycline resistance protein, TetA/multidrug resistance protein MdtG + Major facilitator superfamily + Major facilitator superfamily domain Bcin03g04330 499 Bcin03g04340 420 Six-bladed beta-propeller, TolB-like Bcin03g04350 211 Effector(V2)|Effector(V1) Bcin03g04360 3941 SM cluster PKS3 (KE) Bcpks3, Polyketide synthase Bcin03g04370 378 SM cluster PKS3 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin03g04380 165 SM cluster PKS3//Effector(V2)|Effector(V1) EthD domain + Dimeric alpha-beta barrel Bcin03g04390 431 SM cluster PKS3//Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin03g04400 577 SM cluster PKS3 Major facilitator superfamily + Major facilitator superfamily domain Bcin03g04410 405 SM cluster PKS3 Bcin03g04420 374 SM cluster PKS3 Bcace2, Transcription factor_Cys6 Bcin03g04430 539 SignalP-noTM Bcin03g04440 838 Cys2His2 transcription factor Zinc finger, C2H2-like Bcin03g04450 301 RTA-like protein Bcin03g04460 477 Bcin03g04470 926 Bcin03g04480 300 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin03g04490 312 Bcin03g04500 942 Bcin03g04510 152 Protein trafficking Pga2 Bcin03g04520 112 Effector(V1) "Bcmhf1, similar to yeast MHF1, Component of the heterotetrameric MHF histone-fold complex; in humans the MHF complex interacts with both DNA and Mph1p ortholog FANCM, a Fanconi anemia complementation group protein, to stabilize and remodel blocked replication forks and repair damaged DNA; mhf1 srs2 double mutants are MMS hypersensitive; ortholog of human centromere constitutive-associated network (CCAN) subunit CENP-S, also known as MHF1 [Source:SGD;Acc:S000007626]" Bcin03g04530 231 F-box domain Bcin03g04540 383 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin03g04550 829 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin03g04560 624 Leucine-rich repeat domain, L domain-like Bcin03g04570 774 Protein of unknown function DUF3433 Bcin03g04580 197 Effector(V2)|Effector(V1) Bcin03g04590 649 Bcin03g04600 793 yes Bcrid1, DNA methyltransferase Bcin03g04610 283 "Bcsec65, similar to yeast SEC65, Subunit of the signal recognition particle (SRP); involved in protein targeting to the ER; interacts with Srp54p; homolog of mammalian SRP19 [Source:SGD;Acc:S000004573]" Bcin03g04620 453 Bcin03g04630 556 "Bcgcd1, similar to yeast GCD1, Gamma subunit of the translation initiation factor eIF2B; the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression [Source:SGD;Acc:S000005786]" Bcin03g04640 465 Zinc finger, CCCH-type Bcin03g04650 394 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin03g04660 262 Effector(V2) Transcriptional regulator PAI 2-type + FMN-binding split barrel Bcin03g04670 599 Leucine-rich repeat domain, L domain-like Bcin03g04680 603 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin03g04690 894 BcPIO4, Gene with a peak of expression during the Outset of colonization Bcin03g04700 271 Serine hydrolase FSH + Alpha/Beta hydrolase fold Bcin03g04710 596 Bcin03g04720 204 Effector(V1) Bcin03g04730 582 Protease Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin03g04740 550 Effector(V2)|Effector(V1) BTB/POZ fold Bcin03g04750 951 EF-hand domain + Mechanosensitive ion channel MscS + Like-Sm (LSM) domain + EF-hand domain pair + EF-Hand 1, calcium-binding site Bcin03g04760 265 Alanine racemase, N-terminal + Uncharacterised protein family UPF0001 + PLP-binding barrel Bcin03g04770 102 Effector(V2)|Effector(V1) Bcin03g04780 391 Taurine catabolism dioxygenase TauD/TfdA Bcin03g04790 318 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin03g04800 1193 IQ motif, EF-hand binding site + HECT Bcin03g04810 790 RNA recognition motif domain + Polyadenylate-binding protein/Hyperplastic disc protein + RNA recognition motif domain, eukaryote + Polyadenylate binding protein, human types 1, 2, 3, 4 + Nucleotide-binding alpha-beta plait domain Bcin03g04820 759 Ankyrin repeat-containing domain Bcin03g04830 706 Universal stress protein A + UspA + Rossmann-like alpha/beta/alpha sandwich fold Bcin03g04840 334 "Bcrsm7, similar to yeast RSM7, Mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S7 ribosomal protein [Source:SGD;Acc:S000003874]" Bcin03g04850 96 Double-stranded RNA-binding domain Bcin03g04860 330 2-nitropropane dioxygenase, NPD + Aldolase-type TIM barrel Bcin03g04870 368 Bcin03g04880 460 Bcin03g04890 616 Adenosine/AMP deaminase domain + Metal-dependent hydrolase Bcin03g04900 477 SRP40, C-terminal Bcin03g04910 1468 yes Bcsec3, exocyst subunit Bcin03g04920 455 Major facilitator superfamily + Major facilitator superfamily domain Bcin03g04930 435 Bcin03g04940 1256 Bcin03g04950 111 Effector(V1) Bcin03g04960 324 GTP binding domain + GTP-binding protein, ribosome biogenesis, YsxC + P-loop containing nucleoside triphosphate hydrolase + EngB-type guanine nucleotide-binding (G) domain Bcin03g04970 576 Ubiquitin interacting motif + ENTH/VHS + ENTH domain Bcin03g04980 226 "Bccdc31, similar to yeast CDC31, Calcium-binding component of the spindle pole body (SPB) half-bridge; required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation [Source:SGD;Acc:S000005783]" Bcin03g04990 1974 Protease//Effector(V1) Peptidase S59, nucleoporin + Nuclear protein 96 + Nucleoporin FG repeat Bcin03g05000 586 Bcin03g05010 349 Bcin03g05020 329 Bcin03g05030 234 Bcin03g05040 1079 PAZ domain + Piwi domain + Ribonuclease H-like domain + Domain of unknown function DUF1785 + Argonaute linker 2 domain + Protein argonaute, N-terminal Bcin03g05050 580 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g05060 389 CAZy : CE8PCW pectin//SignalP-noTM//Early secretome Pectinesterase, catalytic + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin03g05070 390 DnaJ domain + DnaJ domain, conserved site Bcin03g05080 309 Nucleic acid-binding, OB-fold + Telomere length regulation Stn1, N-terminal Bcin03g05090 524 CND12, CalciNeurine-Dependant (CND) gene Bcin03g05100 769 Phospholipid/glycerol acyltransferase Bcin03g05110 535 Bcerg27, 3-ketoreductase Bcin03g05120 384 Cyclin, N-terminal + Cyclin-like Bcin03g05130 409 Bcalo3, AMID-like oxidoreductase 3 Bcin03g05140 495 Protease Amidohydrolase 1 + Metal-dependent hydrolase, composite domain + Metal-dependent hydrolase Bcin03g05150 159 Effector(V2)|Effector(V1) Cytochrome b5-like heme/steroid binding domain Bcin03g05160 247 GPR1/FUN34/yaaH Bcin03g05170 592 Protease Alpha/beta hydrolase fold-1 + Fumarylacetoacetase, C-terminal-related + Putative lysophospholipase + Alpha/Beta hydrolase fold Bcin03g05180 666 Fungal trans transcription factor Transcription factor domain, fungi Bcin03g05190 500 Protease Peptidase M54, archaemetzincin Bcin03g05200 866 CAZy : GH81FCW //SignalP-noTM Endo-1,3(4)-beta-glucanase Bcin03g05210 104 Effector(V2)|Effector(V1) Ribosomal protein L27/L41, mitochondrial Bcin03g05220 954 "Bcutp14, similar to yeast UTP14, Subunit of U3-containing Small Subunit (SSU) processome complex; involved in production of 18S rRNA and assembly of small ribosomal subunit [Source:SGD;Acc:S000004558]" Bcin03g05230 595 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g05240 86 Effector(V2) NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1 Bcin03g05250 1171 Zinc finger, PHD-type + MOZ/SAS-like protein + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Acyl-CoA N-acyltransferase + Zinc finger, PHD-finger Bcin03g05260 82 SignalP-noTM//Effector(V2) Bcin03g05270 500 Cytochrome P450 + Cytochrome P450, E-class, CYP52 + Cytochrome P450, conserved site Bcin03g05280 564 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g05290 1021 SignalP-noTM "Bcslp1, similar to yeast SLP1, Glycosylated integral ER membrane protein of unknown function; forms an ER-membrane associated protein complex with Emp65p; member of the SUN-like family of proteins; genetic interactions suggest a role in folding of ER membrane proteins; required for nuclear envelope localization of Mps3p [Source:SGD;Acc:S000005680]" Bcin03g05300 654 Protease Creatinase, N-terminal + Peptidase M24, structural domain + Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site + Creatinase/Aminopeptidase P, N-terminal + Creatinase/Aminopeptidase P/Spt16, N-terminal + Peptidase M24, C-terminal domain Bcin03g05310 1006 Armadillo-like helical + Armadillo-type fold Bcin03g05320 151 FUN14 Bcin03g05330 312 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ + Ribulose-phosphate binding barrel + Aldolase-type TIM barrel + PdxS/SNZ N-terminal domain Bcin03g05340 785 "Bcade5, similar to yeast ADE5,7, Enzyme of the 'de novo' purine nucleotide biosynthetic pathway; contains aminoimidazole ribotide synthetase and glycinamide ribotide synthetase activities [Source:SGD;Acc:S000003203]" Bcin03g05350 349 "Bcthr1, similar to yeast THR1, Homoserine kinase; conserved protein required for threonine biosynthesis; long-lived protein that is preferentially retained in mother cells and forms cytoplasmic filaments; expression is regulated by the GCN4-mediated general amino acid control pathway [Source:SGD;Acc:S000001067]" Bcin03g05360 163 Effector(V1) Histone H3/CENP-A + Histone core + Histone-fold Bcin03g05370 247 Protease Derlin Bcin03g05380 410 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin03g05390 176 "Bcadi1, similar to yeast ADI1, Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed as polycistronic mRNA with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions [Source:SGD;Acc:S000004611]" Bcin03g05400 143 Effector(V1) Bcin03g05410 623 yes Bcklp-7, kinesin Bcin03g05420 204 Protein of unknown function DUF4598 Bcin03g05430 244 Effector(V2) Translation Initiation factor eIF- 4e + Translation Initiation factor eIF- 4e-like domain Bcin03g05440 195 Effector(V1) EF-hand domain pair Bcin03g05450 464 FAD linked oxidase, N-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin03g05460 347 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin03g05470 653 Domain of unknown function DUF4211 Bcin03g05480 925 Protein of unknown function DUF4449 Bcin03g05490 329 Beta-lactamase-like + Hydroxyacylglutathione hydrolase + Hydroxyacylglutathione hydrolase, C-terminal domain Bcin03g05500 228 Protein of unknown function DUF1264 Bcin03g05510 1211 Actin-depolymerising factor homology domain + ADF-H/Gelsolin-like domain Bcin03g05520 588 Bcin03g05530 151 "Bctom22, similar to yeast TOM22, Component of the TOM (Translocase of Outer Membrane) complex; responsible for initial import of mitochondrially directed proteins; mediates interaction between TOM and TIM complexes and acts as a receptor for precursor proteins [Source:SGD;Acc:S000005075]" Bcin03g05540 402 Bestrophin/UPF0187 Bcin03g05550 225 Effector(V2)|Effector(V1) Alcohol dehydrogenase, C-terminal + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin03g05560 330 Bcin03g05570 178 Bcin03g05580 358 Bcin03g05590 624 SignalP-noTM Amidase + Amidase signature domain Bcin03g05600 448 SignalP-noTM//Early secretome Phosphoesterase + Alkaline-phosphatase-like, core domain Bcin03g05610 409 SignalP-noTM//Early secretome Yeast PIR protein repeat Bcin03g05620 451 DnaJ domain Bcin03g05630 319 Bcin03g05640 545 Zinc finger, C6HC-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site + E3 ubiquitin ligase RBR family Bcin03g05650 488 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g05660 391 Bcin03g05670 411 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin03g05680 415 Bcin03g05690 243 Effector(V2)|Effector(V1) NAD(P)-binding domain Bcin03g05700 1026 Actinin-type actin-binding domain, conserved site + Calponin homology domain + EF-hand domain + EF-hand domain pair + EF-hand, Ca insensitive + EF-Hand 1, calcium-binding site Bcin03g05710 618 CAZy : CBM18,CBM18,CBM18,CE4FCW //SignalP-noTM Bccda1, Chitin deacetylase Bcin03g05720 155 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Bcin03g05730 343 Bcin03g05740 726 Pre-rRNA-processing protein RIX1, N-terminal + Armadillo-type fold Bcin03g05750 1165 Tetratricopeptide-like helical domain + Tetratricopeptide repeat Bcin03g05760 298 Transporter Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin03g05770 689 "Bcmek1, similar to yeast MEK1, Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis [Source:SGD;Acc:S000005878]" Bcin03g05780 25 Ribosomal protein L41 Bcin03g05790 449 "Bcrpa49, similar to yeast RPA49, RNA polymerase I subunit A49; essential for nucleolar assembly and for high polymerase loading rate; required for nucleolar localization of Rpa34p [Source:SGD;Acc:S000005192]" Bcin03g05800 566 CAZy : GH13Energy //SignalP-noTM Glycosyl hydrolase, family 13, catalytic domain + Glycosyl hydrolase, family 13, all-beta + Glycoside hydrolase, catalytic domain + Alpha-amylase, domain of unknown function DUF1966, C-terminal + Glycoside hydrolase superfamily Bcin03g05810 167 Effector(V1) Bcin03g05820 329 CAZy : PL1PCW pectin//SignalP-noTM Pectate lyase/Amb allergen + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin03g05830 239 Effector(V1) SGNH hydrolase-type esterase domain Bcin03g05840 288 Crotonase superfamily + Enoyl-CoA hydratase/isomerase, conserved site + ClpP/crotonase-like domain Bcin03g05850 190 "Bcrer1, similar to yeast RER1, Protein involved in retention of membrane proteins; including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER [Source:SGD;Acc:S000000507]" Bcin03g05860 491 "Bcpaf1, similar to yeast PAF1, Component of the Paf1p complex involved in transcription elongation; binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cell cycle-regulated genes; involved in SER3 repression by helping to maintain SRG1 transcription-dependent nucleosome occupancy; homolog of human PD2/hPAF1 [Source:SGD;Acc:S000000483]" Bcin03g05870 674 SignalP-noTM Alpha/Beta hydrolase fold Bcin03g05880 754 "Bcvps9, similar to yeast VPS9, Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF MUK1; required for localization of the CORVET complex to endosomes; similar to mammalian ras inhibitors; contains a VPS9 domain; binds ubiquitin [Source:SGD;Acc:S000004563]" Bcin03g05890 229 CAZy : AA9 //SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Glycoside hydrolase, family 61 Bcin03g05900 463 SignalP-noTM Bcin03g05910 530 SignalP-noTM Bcin03g05920 611 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + Ketopantoate reductase, C-terminal domain Bcin03g05930 276 Bcin03g05940 300 "Bcrrp36, similar to yeast RRP36, Component of 90S preribosomes; involved in early cleavages of the 35S pre-rRNA and in production of the 40S ribosomal subunit [Source:SGD;Acc:S000005813]" Bcin03g05950 426 NLI interacting factor + HAD-like domain Bcin03g05960 415 Bcgst25, Glutathione S-transferase Bcin03g05970 318 "Bcmrps9, similar to yeast MRPS9, Mitochondrial ribosomal protein of the small subunit [Source:SGD;Acc:S000000350]" Bcin03g05980 381 Bcin03g05990 174 "Bccnb1, similar to yeast CNB1, Calcineurin B; regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (stress-response transcription factor); other calcineurin subunit encoded by CNA1 and/or CMP1; regulates function of Aly1p alpha-arrestin; myristoylation by Nmt1p reduces calcineurin activity in response to submaximal Ca signals, is needed to prevent constitutive phosphatase activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001673]" Bcin03g06000 567 "Bcepl1, similar to yeast EPL1, Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex; conserved region at N-terminus is essential for interaction with the NPC (nucleosome core particle); required for autophagy; homologous to Drosophila Enhancer of Polycomb; coding sequence contains length polymorphisms in different strains [Source:SGD;Acc:S000001870]" Bcin03g06010 470 "Bcrkm4, similar to yeast RKM4, Ribosomal lysine methyltransferase; specific for monomethylation of Rpl42ap and Rpl42bp (lysine 55); nuclear SET-domain containing protein [Source:SGD;Acc:S000002665]" Bcin03g06020 349 "Bckae1, similar to yeast KAE1, Highly conserved ATPase of HSP70/DnaK family; essential functional component of the EKC/KEOPS complex, with Bud32p, Cgi121p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription [Source:SGD;Acc:S000001746]" Bcin03g06030 171 Effector(V1) Bcin03g06040 481 CAZy : CBM48 Association with the SNF1 complex (ASC) domain + Immunoglobulin E-set + SNF1 protein kinase subunit beta-2/beta-3 + AMP-activated protein kinase, glycogen-binding domain Bcin03g06050 176 "Bcfap7, similar to yeast FAP7, Essential NTPase required for small ribosome subunit synthesis; mediates processing of the 20S pre-rRNA at site D in the cytoplasm but associates only transiently with 43S preribosomes via Rps14p, may be the endonuclease for site D; depletion leads to accumulation of pre-40S ribosomes in 80S-like ribosomes [Source:SGD;Acc:S000002325]" Bcin03g06060 185 Effector(V2)|Effector(V1) "Bcham1, similar to yeast HAM1, Nucleoside triphosphate pyrophosphohydrolase; active against a wide range of substrates including ITP, dITP and XTP; mediates exclusion of noncanonical purines and pyrimidines from deoxyribonucleoside triphosphate pools; functions together with YJL055W to mediate resistance to 5-FU; specifically reduces the incorporation of 5-FU into RNA without affecting uptake or incorporation of uracil into RNA; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003830]" Bcin03g06070 581 Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin03g06080 1579 "Bcmyo2, similar to yeast MYO2, Type V myosin motor involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle; MYO2 has a paralog, MYO4, that arose from the whole genome duplication [Source:SGD;Acc:S000005853]" Bcin03g06090 398 "Bcnap1, similar to yeast NAP1, Histone chaperone; involved in histone exchange by removing and replacing histone H2A-H2B dimers or histone variant dimers from assembled nucleosomes; involved in the transport of H2A and H2B histones to the nucleus; required for the regulation of microtubule dynamics during mitosis; interacts with mitotic cyclin Clb2p; controls bud morphogenesis; phosphorylated by CK2; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001756]" Bcin03g06100 1336 Transporter P-type ATPase + P-type ATPase, subfamily V + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, cytoplasmic domain N Bcin03g06110 342 S-adenosyl-L-methionine-dependent methyltransferase Bcin03g06120 53 Bcin03g06130 585 "Bcsgv1, similar to yeast SGV1, Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]" Bcin03g06140 474 Cys2His2 transcription factor Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 Bcin03g06150 292 Protease Alpha/beta hydrolase fold-1 + Epoxide hydrolase-like + Alpha/Beta hydrolase fold Bcin03g06160 209 Effector(V2)|Effector(V1) "Bcypt7, similar to yeast YPT7, Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion; interacts with the cargo selection/retromer complex for retrograde sorting; similar to mammalian Rab7 [Source:SGD;Acc:S000004460]" Bcin03g06170 256 Ribosomal protein S3Ae + Ribosomal protein S3Ae, conserved site + 40S ribosomal protein S1/3, eukaryotes Bcin03g06180 471 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + NAD(P)-binding domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Bcin03g06190 128 Bcin03g06200 526 GTP cyclohydrolase N-terminal + GTP cyclohydrolase II Bcin03g06210 140 "Bcelf1, similar to yeast ELF1, Transcription elongation factor with a conserved zinc finger domain; implicated in the maintenance of proper chromatin structure in actively transcribed regions; deletion inhibits Brome mosaic virus (BMV) gene expression [Source:SGD;Acc:S000001643]" Bcin03g06220 245 Effector(V1) "Bcfur1, similar to yeast FUR1, Uracil phosphoribosyltransferase; synthesizes UMP from uracil; involved in the pyrimidine salvage pathway [Source:SGD;Acc:S000001170]" Bcin03g06230 962 Wings apart-like protein Bcin03g06240 187 Effector(V2)|Effector(V1) "Bcrhb1, similar to yeast RHB1, Putative Rheb-related GTPase; involved in regulating canavanine resistance and arginine uptake; member of the Ras superfamily of G-proteins [Source:SGD;Acc:S000000622]" Bcin03g06250 480 "Bcses1, similar to yeast SES1, Cytosolic seryl-tRNA synthetase; class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p [Source:SGD;Acc:S000002430]" Bcin03g06260 384 "Bcmsw1, similar to yeast MSW1, Mitochondrial tryptophanyl-tRNA synthetase [Source:SGD;Acc:S000002676]" Bcin03g06270 274 "Bcrsm10, similar to yeast RSM10, Mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins [Source:SGD;Acc:S000002448]" Bcin03g06280 216 "Bcfcf2, similar to yeast FCF2, Nucleolar protein involved in the early steps of 35S rRNA processing; interacts with Faf1p; member of a transcriptionally co-regulated set of genes called the RRB regulon; essential gene [Source:SGD;Acc:S000004041]" Bcin03g06290 330 CBF/NF-Y/archaeal histone transcription factor "Bchap5, similar to yeast HAP5, Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; complex is heme-activated and glucose repressed; complex is a transcriptional activator and global regulator of respiratory gene expression; required for assembly and DNA binding activity of the complex [Source:SGD;Acc:S000005885]" Bcin03g06300 777 "Bcsec15, similar to yeast SEC15, Essential 113 kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis prior to SNARE-mediated fusion; interacts with and functions as a downstream effector of active, GTP-bound Sec4p, a Rab family GTPase [Source:SGD;Acc:S000003202]" Bcin03g06310 746 RNA recognition motif domain + RNA recognition motif 2 + Nucleotide-binding alpha-beta plait domain Bcin03g06320 311 S-adenosyl-L-methionine-dependent methyltransferase Bcin03g06330 351 SignalP-noTM//Early secretome Protein of unknown function DUF3129 Bcin03g06340 132 Effector(V2)|Effector(V1) Double-stranded RNA-binding domain Bcin03g06350 541 "Bcram1, similar to yeast RAM1, Beta subunit of the CAAX farnesyltransferase (FTase); this complex prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit [Source:SGD;Acc:S000002248]" Bcin03g06360 785 Zn2/Cys6 transcription factor Bcin03g06370 305 Early secretome Ubiquitin-like + Ubiquitin conserved site + Ubiquitin + Ubiquitin-related domain Bcin03g06380 772 "Bcetp1, similar to yeast ETP1, Putative protein of unknown function required for growth on ethanol; contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences [Source:SGD;Acc:S000001002]" Bcin03g06390 364 "Bcpsa1, similar to yeast PSA1, GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase); synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure [Source:SGD;Acc:S000002213]" Bcin03g06400 660 Heterokaryon incompatibility Bcin03g06410 501 Bcvel3, Velvet-like 3, component of the Velvet protein complex, protein implicated in photoreponses Bcin03g06420 1952 "Bcblm10, similar to yeast BLM10, Proteasome activator; binds the core proteasome (CP) and stimulates proteasome-mediated protein degradation by inducing gate opening; required for sequestering CP into proteasome storage granule (PSG) during quiescent phase and for nuclear import of CP in proliferating cells; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200 [Source:SGD;Acc:S000001887]" Bcin03g06430 604 Bcin03g06440 449 CAZy : GT76 "Bcgpi18, similar to yeast GPI18, Functional ortholog of human PIG-V; PIG-V is a mannosyltransferase that transfers the second mannose in glycosylphosphatidylinositol biosynthesis; the authentic, non-tagged protein was localized to mitochondria [Source:SGD;Acc:S000000208]" Bcin03g06450 789 YTH domain Bcin03g06460 355 SM cluster DTC2 HotDog domain Bcin03g06470 550 SM cluster DTC2 Phosphopantetheine attachment site + Acyl carrier protein-like + Polyketide synthase, ketoreductase domain + NAD(P)-binding domain + Polyketide synthase, phosphopantetheine-binding domain + Polyketide synthase, enoylreductase domain Bcin03g06480 497 SM cluster DTC2 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin03g06490 542 SM cluster DTC2 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin03g06500 352 SM cluster DTC2 NADP-dependent oxidoreductase domain Bcin03g06510 505 SM cluster DTC2 Ornithine cyclodeaminase/mu-crystallin + NAD(P)-binding domain + Ornithine cyclodeaminase, N-terminal Bcin03g06520 244 SM cluster DTC2//Effector(V2)|Effector(V1) Carbonic anhydrase + Carbonic anhydrase, prokaryotic-like, conserved site Bcin03g06530 260 Ribosomal protein L7A/L8 + Ribosomal protein L7Ae conserved site + Ribosomal protein L7Ae/L30e/S12e/Gadd45 + Ribosomal protein L7Ae/L8/Nhp2 family + 50S ribosomal protein L30e-like Bcin03g06540 430 "Bcncs6, similar to yeast NCS6, Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs; required for the thiolation of uridine at the wobble position of Gln, Lys, and Glu tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae [Source:SGD;Acc:S000003179]" Bcin03g06550 273 Effector(V2)|Effector(V1) Ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase Bcin03g06560 379 "Bcura3, similar to yeast URA3, Orotidine-5'-phosphate (OMP) decarboxylase; catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound [Source:SGD;Acc:S000000747]" Bcin03g06570 677 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g06580 153 "Bcqcr6, similar to yeast QCR6, Subunit 6 of the ubiquinol cytochrome-c reductase complex; the complex, also known as the cytochrome bc(1) complex or Complex III, is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1; may be loosely associated with the complex since it is easily released into the intermembrane space [Source:SGD;Acc:S000001929]" Bcin03g06590 261 Pleckstrin homology-like domain Bcin03g06600 630 Heat shock protein 70 family + Heat shock protein 70, conserved site + Heat shock protein 70kD, peptide-binding domain + Heat shock protein 70kD, C-terminal domain Bcin03g06610 368 von Willebrand factor, type A Bcin03g06620 599 Bcin03g06630 68 Effector(V2)|Effector(V1) Bcin03g06640 133 Effector(V2)|Effector(V1) Bcin03g06650 153 Bcin03g06660 503 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g06670 626 ATP-grasp fold + ATP-grasp fold, subdomain 2 Bcin03g06680 523 SignalP-TM Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin03g06690 614 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g06700 508 Cytochrome P450 + Cytochrome P450, E-class, CYP52 Bcin03g06710 332 Bcin03g06720 572 Protease PPPDE putative peptidase domain + Thioredoxin-like fold + PUL + Thioredoxin domain + Armadillo-type fold Bcin03g06730 565 Nucleoside phosphatase GDA1/CD39 Bcin03g06740 251 Protease//SignalP-noTM Phosphatidylethanolamine-binding protein PEBP Bcin03g06750 360 Bcin03g06760 237 Bcin03g06770 214 Bcin03g06780 266 Effector(V1) Bcin03g06790 159 Effector(V1) Bcin03g06800 195 Bcin03g06810 1450 MIF4G-like, type 3 + MIF4-like, type 1/2/3 + Armadillo-type fold + Eukaryotic translation initiation factor 4G1, eIF4E-binding domain Bcin03g06820 1358 "Bctsc11, similar to yeast TSC11, Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p); TORC2 is a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; involved in sphingolipid metabolism; contains a RasGEFN domain [Source:SGD;Acc:S000000895]" Bcin03g06830 302 Uricase + Uricase, conserved site Bcin03g06840 540 yes Signaling pathway BcnoxR, NADPH oxidase regulator Bcin03g06850 243 Effector(V2)|Effector(V1) "Bcccs1, similar to yeast CCS1, Copper chaperone for superoxide dismutase Sod1p; involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation; required for regulation of yeast copper genes in response to DNA-damaging agents; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004641]" Bcin03g06860 190 "Bcmrpl23, similar to yeast MRPL23, Mitochondrial ribosomal protein of the large subunit; localizes to vacuole in response to H2O2 [Source:SGD;Acc:S000005676]" Bcin03g06870 154 Cys2His2 transcription factor Zinc finger, C2H2-like Bcin03g06880 242 Bcin03g06890 307 Haemerythrin/HHE cation-binding motif Bcin03g06900 353 CAZy : GT8 Nucleotide-diphospho-sugar transferases Bcin03g06910 925 yes Bcyak1, Member of the dual-specificity tyrosine phosphorylation-regulated protein kinases Bcin03g06920 1212 "Bcrad26, similar to yeast RAD26, Protein involved in transcription-coupled nucleotide excision repair; repairs UV-induced DNA lesions; recruitment to DNA lesions is dependent on an elongating RNA polymerase II; homolog of human CSB protein [Source:SGD;Acc:S000003796]" Bcin03g06930 162 SignalP-TM//SignalP& 0TM& >3cys& Len<300aa Bcin03g06940 869 "Bcnip1, similar to yeast NIP1, eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3); involved in the assembly of preinitiation complex and start codon selection [Source:SGD;Acc:S000004926]" Bcin03g06950 139 Effector(V1) Bcin03g06960 601 A1 cistron-splicing factor, AAR2 Bcin03g06970 150 Effector(V2)|Effector(V1) Ribosomal protein S11 + Ribosomal S11, conserved site Bcin03g06980 439 Effector(V2)|Effector(V1) "Bctyr1, similar to yeast TYR1, Prephenate dehydrogenase involved in tyrosine biosynthesis; expression is dependent on phenylalanine levels [Source:SGD;Acc:S000000370]" Bcin03g06990 143 Effector(V2)|Effector(V1) Ribosomal protein S9 + Ribosomal protein S5 domain 2-type fold, subgroup + Ribosomal protein S5 domain 2-type fold + Ribosomal protein S9, conserved site Bcin03g07000 260 "Bcsnf8, similar to yeast SNF8, Component of the ESCRT-II complex; ESCRT-II is involved in ubiquitin-dependent sorting of proteins into the endosome; appears to be functionally related to SNF7; involved in glucose derepression [Source:SGD;Acc:S000005923]" Bcin03g07010 170 Bcin03g07020 466 Cys2His2 transcription factor Bccon7, Cys2His2 transcription factor Bcin03g07030 947 "Bcpuf3, similar to yeast PUF3, Protein of the mitochondrial outer surface; links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins [Source:SGD;Acc:S000003936]" Bcin03g07040 61 Effector(V2)|Effector(V1) Bcin03g07050 190 Effector(V1) Bcin03g07060 189 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa DOMON domain + Cellobiose dehydrogenase, cytochrome domain Bcin03g07070 510 Thiaminase-2/PQQC + Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase + Pyridoxamine kinase/Phosphomethylpyrimidine kinase + Haem oxygenase-like, multi-helical + Thiaminase II + Ribokinase-like Bcin03g07080 574 ATP-dependent RNA helicase DEAD-box, conserved site + Helicase, C-terminal + DEAD/DEAH box helicase domain + Helicase superfamily 1/2, ATP-binding domain + RNA helicase, DEAD-box type, Q motif + P-loop containing nucleoside triphosphate hydrolase Bcin03g07090 240 Bcin03g07100 659 CAZy : GT90 Lipopolysaccharide-modifying protein Bcin03g07110 130 Effector(V2)|Effector(V1) Ribosomal protein S8 Bcin03g07120 149 Effector(V1) "Bcrps12, similar to yeast RPS12, Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S12, no bacterial homolog [Source:SGD;Acc:S000005896]" Bcin03g07130 124 Effector(V1) Peptidyl-prolyl cis-trans isomerase, PpiC-type Bcin03g07140 240 Cysteine dioxygenase type I + RmlC-like cupin domain + RmlC-like jelly roll fold Bcin03g07150 1084 "Bcpus7, similar to yeast PUS7, Pseudouridine synthase; catalyzes pseudouridylation at positions 35 and 56 in U2 snRNA, position 50 in 5S rRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); also pseudouridylates some mRNAs; relocates from nucleus to cytoplasm during heat shock and differentially modifies some mRNAs during heat shock; conserved in archaea, vertebrates, and some bacteria [Source:SGD;Acc:S000005769]" Bcin03g07160 514 SRA-YDG + PUA-like domain Bcin03g07170 603 S-adenosyl-L-methionine-dependent methyltransferase Bcin03g07180 109 Effector(V1) Antibiotic biosynthesis monooxygenase-like domain + Dimeric alpha-beta barrel Bcin03g07190 519 yes Bcmkk1, MAPKK involved in the protein kinase C signaling pathway Bcin03g07200 545 ATP-dependent RNA helicase DEAD-box, conserved site + Helicase, C-terminal + DEAD/DEAH box helicase domain + Helicase superfamily 1/2, ATP-binding domain + RNA helicase, DEAD-box type, Q motif + P-loop containing nucleoside triphosphate hydrolase Bcin03g07210 373 Protease//Effector(V2)|Effector(V1) Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold + Lipase, GDXG, putative serine active site Bcin03g07220 263 S-adenosyl-L-methionine-dependent methyltransferase Bcin03g07230 710 Protease Alpha/beta hydrolase fold-1 + Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal + Alpha/Beta hydrolase fold Bcin03g07240 447 "Bctuf1, similar to yeast TUF1, Mitochondrial translation elongation factor Tu; comprises both GTPase and guanine nucleotide exchange factor activities, while these activities are found in separate proteins in S. pombe and humans [Source:SGD;Acc:S000005713]" Bcin03g07250 1352 Armadillo-like helical + TATA-binding protein interacting (TIP20) + Armadillo-type fold Bcin03g07260 263 Bcin03g07270 1120 Uncharacterised protein family Cys-rich Bcin03g07280 312 "Bctem1, similar to yeast TEM1, GTP-binding protein of the Ras superfamily; involved in termination of M-phase; controls actomyosin and septin dynamics during cytokinesis [Source:SGD;Acc:S000004529]" Bcin03g07290 173 Effector(V1) "Bcgcv3, similar to yeast GCV3, H subunit of the mitochondrial glycine decarboxylase complex; glycine decarboxylase is required for the catabolism of glycine to 5,10-methylene-THF; also required for all protein lipoylation; expression is regulated by levels of 5,10-methylene-THF [Source:SGD;Acc:S000000042]" Bcin03g07300 379 "Bchem3, similar to yeast HEM3, Porphobilinogen deaminase; catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in heme biosynthesis; localizes to the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p, but not by levels of heme [Source:SGD;Acc:S000002364]" Bcin03g07310 340 Bcin03g07320 392 SignalP-noTM//Early secretome Ribonuclease T2-like + Ribonuclease T2, active site + Ribonuclease T2, His active site 2 Bcin03g07330 270 Effector(V2)|Effector(V1) Class II aldolase/adducin N-terminal Bcin03g07340 272 SignalP-noTM//Effector(V1) Bcin03g07350 340 Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin03g07360 385 CAZy : PL1PCW pectin//SignalP-noTM Pectate lyase/Amb allergen + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin03g07370 309 Bcin03g07380 242 Emopamil-binding protein + EXPERA domain Bcin03g07390 71 yes Effector(V1) Bcccg1, Clock Control Gene 1 Bcin03g07400 353 Sucraseferredoxin-like + Thioredoxin-like fold Bcin03g07410 716 Phospholipase D/Transphosphatidylase + Ubiquitin interacting motif + Tyrosyl-DNA phosphodiesterase I + Tyrosyl-DNA phosphodiesterase C-terminal domain Bcin03g07420 507 yes Signaling pathway Bcreg1, Putative transcriptional regulator Bcin03g07430 328 "Bccrd1, similar to yeast CRD1, Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; required to maintain tubular mitochondrial morphology and functions in mitochondrial fusion; also required for normal vacuolar ion homeostasis [Source:SGD;Acc:S000002301]" Bcin03g07440 679 Transporter "Bcavt1, similar to yeast AVT1, Vacuolar transporter; imports large neutral amino acids into the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters [Source:SGD;Acc:S000003761]" Bcin03g07450 290 "Bcbmt2, similar to yeast BMT2, Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; methylates adenine (m1A) of the large subunit (LSU) rRNA at position 2142; belongs to Rossmann fold superfamily; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YBR141C is not an essential gene [Source:SGD;Acc:S000000345]" Bcin03g07460 154 Effector(V2)|Effector(V1) "Bcrpl25, similar to yeast RPL25, Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23 [Source:SGD;Acc:S000005487]" Bcin03g07470 96 "Bctim8, similar to yeast TIM8, Mitochondrial intermembrane space protein; forms a complex with Tim13p that delivers a subset of hydrophobic proteins to the TIM22 complex for inner membrane insertion; homolog of human TIMM8A, implicated in Mohr-Tranebjaerg syndrome [Source:SGD;Acc:S000007348]" Bcin03g07480 636 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB Bcin03g07490 103 Effector(V1) Microsomal signal peptidase 12kDa subunit Bcin03g07500 120 Effector(V2)|Effector(V1) "Bchrt1, similar to yeast HRT1, RING-H2 domain core subunit of multiple ubiquitin ligase complexes; subunit of Skp1-Cullin-F-box (SCF) that tethers the Cdc34p (E2) and Cdc53p (cullin) SCF subunits, and is required for degradation of Gic2p, Far1p, Sic1p and Cln2p; subunit of the Rtt101p-Mms1p-Mms22p ubiquitin ligase that stabilizes replication forks after DNA lesions; subunit of the Cul3p-Elc1p-Ela1p ubiquitin ligase involved in Rpb1p degradation as part of transcription-coupled repair [Source:SGD;Acc:S000005493]" Bcin03g07510 491 Bcin03g07520 685 "Bcmto1, similar to yeast MTO1, Mitochondrial protein; forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants [Source:SGD;Acc:S000003205]" Bcin03g07530 643 "Bcksp1, similar to yeast KSP1, Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001124]" Bcin03g07540 256 HAD-like domain + Enolase-phosphatase E1 + Enolase-phosphatase E1, eukaryotes Bcin03g07550 561 Acyl-CoA N-acyltransferase Bcin03g07560 706 Centromere protein I Bcin03g07570 106 Small subunit of serine palmitoyltransferase-like Bcin03g07580 210 SignalP-noTM Peptide chain release factor class I/class II + Double-stranded RNA-binding domain Bcin03g07590 291 Alpha/beta hydrolase fold-1 + Epoxide hydrolase-like + Putative lysophospholipase + Alpha/Beta hydrolase fold Bcin03g07600 590 Leucine-rich repeat domain, L domain-like Bcin03g07610 449 Rad9/Ddc1 + Rad9 Bcin03g07620 362 "Bcats1, similar to yeast ATS1, Protein required for modification of wobble nucleosides in tRNA; acts with Elongator complex, Kti11p, and Kti12p; has a potential role in regulatory interactions between microtubules and the cell cycle [Source:SGD;Acc:S000000018]" Bcin03g07630 249 Ribosomal protein L7, eukaryotic + Ribosomal protein L30, N-terminal + Ribosomal protein L30, ferredoxin-like fold domain Bcin03g07640 260 "Bcisa2, similar to yeast ISA2, Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa1p and possibly Iba57p; localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations [Source:SGD;Acc:S000006271]" Bcin03g07650 348 NAD(P)-binding domain Bcin03g07660 501 Aminotransferase class V domain + Kynureninase + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin03g07670 1058 "Bcgdh2, similar to yeast GDH2, NAD(+)-dependent glutamate dehydrogenase; degrades glutamate to ammonia and alpha-ketoglutarate; expression sensitive to nitrogen catabolite repression and intracellular ammonia levels; genetically interacts with GDH3 by suppressing stress-induced apoptosis [Source:SGD;Acc:S000002374]" Bcin03g07680 289 S-adenosyl-L-methionine-dependent methyltransferase Bcin03g07690 552 Bcin03g07700 172 Effector(V2)|Effector(V1) Chitin synthesis regulation, Congo red resistance, RCR protein Bcin03g07710 183 Effector(V1) Small GTP-binding protein domain + Small GTPase superfamily, ARF/SAR type + Small GTPase superfamily, ARF type + P-loop containing nucleoside triphosphate hydrolase Bcin03g07720 1207 "Bcrpa135, similar to yeast RPA135, RNA polymerase I second largest subunit A135 [Source:SGD;Acc:S000006214]" Bcin03g07730 653 SignalP-noTM Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin03g07740 283 Cell fusion protein Dni1/Fig1 Bcin03g07750 393 Bcin03g07760 430 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g07770 417 Bcalo4, AMID-like oxidoreductase 4 Bcin03g07780 209 SignalP-noTM Bcin03g07790 291 SignalP-noTM Bcin03g07800 964 Gamma-tubulin complex component protein Bcin03g07810 283 Chromatin modification-related protein Eaf7/MRGBP Bcin03g07820 253 ETC complex I subunit Bcin03g07830 1228 Bcin03g07840 477 Bcin03g07850 535 Bcprd10, Peroxidase Bcin03g07860 127 Effector(V2)|Effector(V1) Bcin03g07870 792 Tetrapeptide transporter, OPT1/isp4 + Oligopeptide transporter, OPT superfamily Bcin03g07880 354 Bcin03g07890 855 Lysophospholipase, catalytic domain + Acyl transferase/acyl hydrolase/lysophospholipase Bcin03g07900 654 yes "Bcexo70, similar to yeast EXO70, Subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis prior to SNARE-mediated fusion; PtdIns[4,5]P2-binding protein that localizes to exocytic sites in an actin-independent manner, targeting and anchoring the exocyst with Sec3p; involved in exocyst assembly; direct downstream effector of Rho3p and Cdc42p; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000003621]" Bcin03g07910 639 "Bccat2, similar to yeast CAT2, Carnitine acetyl-CoA transferase; present in both mitochondria and peroxisomes; transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes [Source:SGD;Acc:S000004506]" Bcin03g07920 423 "Bcnam9, similar to yeast NAM9, Mitochondrial ribosomal component of the small subunit [Source:SGD;Acc:S000005081]" Bcin03g07930 453 "Bclhp1, similar to yeast LHP1, RNA binding protein required for maturation of tRNA and U6 snRNA; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen [Source:SGD;Acc:S000002209]" Bcin03g07940 398 "Bcmrpl3, similar to yeast MRPL3, Mitochondrial ribosomal protein of the large subunit; located in close proximity to the polypeptide exit channel of the ribosome; mutations in human homolog MRPL44 cause childhood cardiomyopathy; human MRPL44 deficiency results in inefficient assembly of the mitochondrial ribosome, and in tissue-specific respiratory chain deficiency, manifesting as either Complex I+Complex IV or Complex IV deficiency, depending on a cell type [Source:SGD;Acc:S000004626]" Bcin03g07950 96 Effector(V2)|Effector(V1) Bcin03g07960 897 "Bcmcm3, similar to yeast MCM3, Protein involved in DNA replication; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex [Source:SGD;Acc:S000000758]" Bcin03g07970 442 "Bcmak32, similar to yeast MAK32, Protein necessary for stability of L-A dsRNA-containing particles [Source:SGD;Acc:S000000612]" Bcin03g07980 547 "Bcsrv2, similar to yeast SRV2, CAP (cyclase-associated protein); N-terminus binds adenylate cyclase and facilitates activation by RAS; N-terminus forms novel hexameric star-shaped shuriken structures that directly catalyze cofilin-mediated severing of actin filaments; C-terminus, in physically and genetically separate activity, binds and recycles cofilin bound, ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis [Source:SGD;Acc:S000005082]" Bcin03g07990 569 Transporter Amino acid/polyamine transporter I Bcin03g08000 817 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Zinc finger, PHD-type + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, PHD-type, conserved site Bcin03g08010 697 Heat shock protein 70 family Bcin03g08020 205 Effector(V2)|Effector(V1) GNAT domain + Acyl-CoA N-acyltransferase Bcin03g08030 229 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin03g08040 519 Transcription initiation factor Rrn11 Bcin03g08050 2138 yes SM cluster Melanin (KE) Bcpks13, Polyketide synthase, involved in DHN melanin biosynthesis Bcin03g08060 587 SM cluster Melanin Protein of unknown function DUF3112 Bcin03g08070 272 SM cluster Melanin//Protease Alpha/beta hydrolase fold-1 + Epoxide hydrolase-like + Putative lysophospholipase + Alpha/Beta hydrolase fold Bcin03g08080 610 yes Zn2/Cys6 transcription factor//SM cluster Melanin Bcztf2, Zn2/Cys6 transcription factor, involved in DHN melanin biosynthesis Bcin03g08090 650 yes Zn2/Cys6 transcription factor//SM cluster Melanin Bcztf1, Zn2/Cys6 transcription factor, involved in DHN melanin biosynthesis Bcin03g08100 266 yes SM cluster Melanin//Effector(V2)|Effector(V1) Bcbrn2, Tetrahydroxynaphtalene (THN) reductase, involved in DHN melanin biosynthesis Bcin03g08110 167 yes SM cluster Melanin Bcscd1, Scytalone dehydratase, involved in DHN melanin biosynthesis Bcin03g08120 667 Monooxygenase, FAD-binding + Thioredoxin-like fold + Phenol hydroxylase, C-terminal dimerisation domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin03g08130 299 Intradiol ring-cleavage dioxygenase, C-terminal + Catechol dioxygenase, N-terminal + Intradiol ring-cleavage dioxygenase, core Bcin03g08140 572 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin03g08150 548 PAS domain Bcin03g08160 298 Yip1 domain Bcin03g08170 337 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin03g08180 482 Calcium/proton exchanger CAX + Sodium/calcium exchanger membrane region Bcin03g08190 492 Bcin03g08200 399 Bcin03g08210 148 Effector(V1) Bcin03g08220 534 "Bcyrb2, similar to yeast YRB2, Protein of unknown function; involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; relocalizes to the cytosol in response to hypoxia; not essential for viability [Source:SGD;Acc:S000001325]" Bcin03g08230 173 yes SignalP-noTM//Effector(V1) BcHsbA1, hydrophobic surface binding protein Bcin03g08240 100 Effector(V1)//Early secretome "Bcacb1, similar to yeast ACB1, Acyl-CoA-binding protein; transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes; subject to starvation-induced, Grh1p-mediated unconventional secretion; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003269]" Bcin03g08250 639 Tyrosyl-DNA phosphodiesterase I + Tyrosyl-DNA phosphodiesterase C-terminal domain Bcin03g08260 797 SignalP-noTM Thioredoxin-like fold + Thioredoxin domain Bcin03g08270 615 Bcin03g08280 220 Bcin03g08290 1087 SNF5/SMARCB1/INI1 Bcin03g08300 593 RNA recognition motif domain Bcin03g08310 241 Effector(V2)|Effector(V1) Bcin03g08320 636 Bcin03g08330 392 Bcin03g08340 1166 "Bchrq1, similar to yeast HRQ1, 3'-5' DNA helicase that has DNA strand annealing activity; helicase activity is stimulated by fork structure and 3'-tail length of substrates; acts with Rad4p in nucleotide-excision repair; belongs to the widely conserved RecQ family of proteins which are involved in maintaining genomic integrity; similar to the human RecQ4p implicated in Rothmund-Thomson syndrome (RTS) [Source:SGD;Acc:S000002699]" Bcin03g08350 371 "Bcurh1, similar to yeast URH1, Uridine nucleosidase (uridine-cytidine N-ribohydrolase); cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways [Source:SGD;Acc:S000002808]" Bcin03g08360 220 Exon junction complex, Pym Bcin03g08370 65 Effector(V2) Cytochrome b-c1 complex subunit 9 Bcin03g08380 2239 Zinc finger, N-recognin + Adaptor protein ClpS, core + Winged helix-turn-helix DNA-binding domain + Zinc finger, RING/FYVE/PHD-type Bcin03g08390 139 Bcin03g08400 514 Bcin03g08410 1459 Bcin03g08420 263 Bcin03g08430 510 SignalP-TM Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin03g08440 530 RED-like, N-terminal Bcin03g08450 514 "Bcapn1, similar to yeast APN1, Major apurinic/apyrimidinic endonuclease; 3'-repair diesterase; involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine; genetically interacts with NTG1 to maintain mitochondrial genome integrity [Source:SGD;Acc:S000001597]" Bcin03g08460 653 Bcin03g08470 335 Bcin03g08480 225 Bcin03g08490 1239 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Mad3-like + Mad3/BUB1 homology region 1 + Mitotic checkpoint serine/threonine protein kinase Bub1/Mitotic spindle checkpoint component Mad3 Bcin03g08500 299 Bcin03g08510 306 Bcin03g08520 359 Bcin03g08530 932 ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin03g08540 421 Bcin03g08550 81 Effector(V2)|Effector(V1) Bcin03g08560 380 Bcin03g08570 481 Bcnde4, External NADH dehydrogenase Bcin03g08580 1501 SNF2-related + Helicase, C-terminal + P-loop containing nucleoside triphosphate hydrolase Bcin03g08590 339 Bcin03g08600 508 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin03g08610 498 "Bcisc1, similar to yeast ISC1, Inositol phosphosphingolipid phospholipase C; mitochondrial membrane localized; hydrolyzes complex sphingolipids to produce ceramide; activates genes required for non-fermentable carbon source metabolism during the diauxic shift; activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol; mediates Na+ and Li+ halotolerance [Source:SGD;Acc:S000000821]" Bcin03g08620 321 Bcin03g08630 286 FMN-binding split barrel + Pyridoxamine 5'-phosphate oxidase-related Bcin03g08640 589 Amidase + Amidase, conserved site + Amidase signature domain Bcin03g08650 599 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin03g08660 843 Effector(V1) Cullin, N-terminal + Winged helix-turn-helix DNA-binding domain + Cullin homology + Cullin repeat-like-containing domain + Cullin protein, neddylation domain Bcin03g08670 165 Effector(V1) "Bczim17, similar to yeast ZIM17, Protein co-chaperone with a zinc finger motif; essential for protein import into mitochondria; may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix; required for the maintenance of Ssc1p solubility and assists in the functional interaction of Ssc1p with substrate proteins [Source:SGD;Acc:S000005254]" Bcin03g08680 2638 "Bcutp20, similar to yeast UTP20, Component of the small-subunit (SSU) processome; SSU processome is involved in the biogenesis of the 18S rRNA [Source:SGD;Acc:S000000100]" Bcin03g08690 544 "Bcdrn1, similar to yeast DRN1, Splicing factor that modulates turnover of branched RNAs by Dbr1p; interacts with spliceosomal components and branched RNA splicing products; enhances Dbr1p debranching in vitro; conserved protein with domain organization identical from yeast to human; N-terminal homology to Dbr1p N-terminus, but Dbr1p catalytic residues not conserved; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003325]" Bcin03g08700 223 Bcin03g08710 845 CAZy : GH3PCW/FCW //SignalP-noTM Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Glycoside hydrolase, family 3, active site + Fibronectin type III-like domain Bcin03g08720 356 Bcin03g08730 699 Bcin03g08740 412 Bcin03g08750 330 Bcin03g08760 329 Bcin03g08770 381 Bcin03g08780 460 Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin03g08790 475 Bcin03g08800 454 "Bcqri7, similar to yeast QRI7, Protein involved in threonylcarbamoyl adenosine biosynthesis; Sua5p and Qri7p are necessary and sufficient for RNA t6A modification in vitro; highly conserved mitochondrial protein; essential for t6A modification of mitochondrial tRNAs that decode ANN codons; similar to Kae1p and E. coli YgjD, both of which are also required for tRNA t6A modification; when directed to the cytoplasm, complements the essential function of Kae1p in the KEOPS complex [Source:SGD;Acc:S000002262]" Bcin03g08810 667 Bcin03g08820 1021 Ankyrin repeat + Ankyrin repeat-containing domain Bcin03g08830 601 "Bctep1, similar to yeast TEP1, PTEN homolog with no demonstrated inositol lipid phosphatase activity; plays a role in normal sporulation; homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 and fission yeast ptn1 [Source:SGD;Acc:S000005072]" Bcin03g08840 794 SignalP-noTM Bcin03g08850 122 Effector(V2)|Effector(V1) "Bclsm4, similar to yeast LSM4, Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000000914]" Bcin03g08860 619 Pentatricopeptide repeat Bcin03g08870 274 BTB/POZ-like + BTB/POZ fold Bcin03g08880 170 Effector(V2) Bcin03g08890 447 Bcin03g08900 1228 Bcin03g08910 496 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin03g08920 579 Major facilitator superfamily + Major facilitator superfamily domain Bcin03g08930 244 Bcin03g08940 120 Effector(V1) Bcin03g08950 550 Amino acid/polyamine transporter I + Amino acid permease/ SLC12A domain Bcin03g08960 221 Effector(V2)|Effector(V1) Bcdao9, D-amino acid oxidase Bcin03g08970 506 FAD linked oxidase, N-terminal + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin03g08980 704 Heterokaryon incompatibility Bcin03g08990 342 Bcin03g09000 587 Septin + P-loop containing nucleoside triphosphate hydrolase + Septin-type guanine nucleotide-binding (G) domain Bcin03g09010 778 Bcin03g09020 662 General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin03g09030 325 Bcin03g09040 524 Bcin03g09050 452 Bcin03g09060 475 Bcin03g09070 413 Bcin03g09080 1007 Bcin03g09090 179 Bcin03g09100 506 CBF/NF-Y/archaeal histone transcription factor "Bcbur6, similar to yeast BUR6, Subunit of a heterodimeric NC2 transcription regulator complex; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha; complex also includes Ncb2p [Source:SGD;Acc:S000000961]" Bcin03g09110 457 Protease "Bcmap2, similar to yeast MAP2, Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p [Source:SGD;Acc:S000000187]" Bcin03g09120 492 Bcin03g09130 288 P-loop containing nucleoside triphosphate hydrolase Bcin03g09140 582 SignalP-noTM Bcin03g09150 647 Transporter Tetracycline resistance protein, TetA/multidrug resistance protein MdtG + Major facilitator superfamily + Major facilitator superfamily domain Bcin03g09160 623 SignalP-noTM Bcin03g09170 594 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin03g09180 341 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin03g09190 1118 Sterol-sensing domain + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + Sterol regulatory element-binding protein cleavage-activating protein Bcin03g09200 377 Bcin03g09210 418 Early secretome Nitrous oxide reductase, N-terminal + WD40/YVTN repeat-like-containing domain + Lactonase, 7-bladed beta propeller Bcin03g09220 253 Effector(V2) Bcin03g09230 430 Bcin03g09240 322 CAZy : GH16FCW Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin03g09250 860 "Bccoq8, similar to yeast COQ8, Protein required for ubiquinone biosynthesis and respiratory growth; exhibits genetic interaction with COQ9, suggesting a common function; similar to prokaryotic proteins involved in early steps of ubiquinone biosynthesis; COQ8 has a paralog, YBR230W-A, that arose from the whole genome duplication [Source:SGD;Acc:S000003087]" Bcin03g09260 453 Nuclear protein DGCR14 Bcin03g09270 476 "Bcppt1, similar to yeast PPT1, Protein serine/threonine phosphatase; regulates Hsp90 chaperone by affecting its ATPase and cochaperone binding activities; has similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth [Source:SGD;Acc:S000003355]" Bcin03g09280 448 "Bclys9, similar to yeast LYS9, Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, the seventh step in lysine biosynthesis pathway; exhibits genetic and physical interactions with TRM112 [Source:SGD;Acc:S000005333]" Bcin03g09290 258 Derlin + Reeler domain Bcin03g09300 290 Carbon-nitrogen hydrolase Bcin03g09310 655 SignalP-noTM Leucine-rich repeat domain, L domain-like Bcin03g09314 582 FAD-binding 8 + Ferric reductase, NAD binding + Ferric reductase transmembrane component-like domain + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel Bcin03g09316 192 Bcin03g09318 251 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin03g09320 398 Bcin04g00010 282 Fungal N-terminal domain of STAND protein Bcin04g00020 935 Kinesin light chain + Tetratricopeptide-like helical domain + P-loop containing nucleoside triphosphate hydrolase Bcin04g00030 550 CAZy : GH15Energy //Early secretome Glucoamylase + Glucoamylase, starch-binding + Six-hairpin glycosidase-like + Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family + Six-hairpin glycosidase Bcin04g00040 539 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin04g00050 474 Indoleamine 2,3-dioxygenase Bcin04g00060 242 Effector(V2)|Effector(V1) Protein of unknown function DUF541 Bcin04g00070 233 "Bcmrpl24, similar to yeast MRPL24, Mitochondrial ribosomal protein of the large subunit; two mitochondrial ribosomal proteins, YmL14 and YmL24, have been assigned to the same gene [Source:SGD;Acc:S000004806]" Bcin04g00080 242 Bcin04g00090 244 Bcin04g00100 1034 "Bcvam6, similar to yeast VAM6, Subunit of the HOPS endocytic tethering complex; vacuole membrane protein that functions as a Rab GTPase effector, interacting with both GTP- and GDP-bound conformations of Ypt7p, facilitating tethering and promoting several membrane fusion events at the late endosome and vacuole; required for both membrane and protein trafficking [Source:SGD;Acc:S000002235]" Bcin04g00110 117 EKC/KEOPS complex, subunit Gon7 Bcin04g00120 886 HbrB-like + Cullin repeat-like-containing domain Bcin04g00130 779 LIM-domain binding protein/SEUSS Bcin04g00140 1165 "Bclys2, similar to yeast LYS2, Alpha aminoadipate reductase; catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p [Source:SGD;Acc:S000000319]" Bcin04g00150 616 Bcin04g00160 264 Bcin04g00170 299 Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin04g00180 224 Effector(V2)|Effector(V1) Bcin04g00190 657 Bcin04g00200 392 "Bchem2, similar to yeast HEM2, Aminolevulinate dehydratase; a homo-octameric enzyme, catalyzes the conversion of 5-aminolevulinate to porphobilinogen, the second step in heme biosynthesis; enzymatic activity is zinc-dependent; localizes to the cytoplasm and nucleus [Source:SGD;Acc:S000003008]" Bcin04g00210 426 Acyl transferase domain + Acyl transferase + Acyl transferase/acyl hydrolase/lysophospholipase + Malonyl-CoA ACP transacylase, ACP-binding + Polyketide synthase, acyl transferase domain Bcin04g00220 205 Effector(V2)|Effector(V1) Trafficking protein particle complex subunit 2 + Longin-like domain Bcin04g00230 330 Protease Dienelactone hydrolase + Alpha/Beta hydrolase fold Bcin04g00240 609 "Bcrfa1, similar to yeast RFA1, Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; role in DNA catenation/decatenation pathway of chromosome disentangling; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000000065]" Bcin04g00250 494 Bcin04g00260 449 "Bcpro2, similar to yeast PRO2, Gamma-glutamyl phosphate reductase; catalyzes the second step in proline biosynthesis [Source:SGD;Acc:S000005850]" Bcin04g00270 232 SignalP-noTM Bcin04g00280 646 Transcription regulator HTH, APSES-type DNA-binding domain + KilA, N-terminal/APSES-type HTH, DNA-binding Bcin04g00290 264 BRCT domain Bcin04g00300 766 Central kinetochore-associated Bcin04g00310 163 Effector(V2)|Effector(V1) Translation initiation factor SUI1 Bcin04g00320 233 Effector(V2) NADH:ubiquinone oxidoreductase-like, 20kDa subunit + NADH-ubiquinone oxidoreductase, 20 Kd subunit Bcin04g00330 487 "Bcpct1, similar to yeast PCT1, Cholinephosphate cytidylyltransferase; a rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding; contains an element within the regulatory domain involved in both silencing and activation of enzymatic activity [Source:SGD;Acc:S000003434]" Bcin04g00340 439 yes Signaling pathway Bcptc3, Type 2C Ser/Thr phosphatase (PP2C) Bcin04g00350 115 Bcin04g00360 96 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin04g00370 676 Bcin04g00380 269 DNA/RNA-binding protein Alba-like Bcin04g00390 125 Effector(V1) "Bcvtc1, similar to yeast VTC1, Subunit of the vacuolar transporter chaperone (VTC) complex; VTC complex is involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion; also has mRNA binding activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000874]" Bcin04g00400 163 Tctex-1 Bcin04g00410 310 F-box domain Bcin04g00420 672 CAZy : GH71,CBM24FCW //SignalP-noTM Glycoside hydrolase, family 71 Bcin04g00430 232 Ion transport domain + Voltage-dependent channel, four helix bundle domain Bcin04g00440 194 Effector(V2)|Effector(V1) "Bcsgn1, similar to yeast SGN1, Cytoplasmic RNA-binding protein; contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation [Source:SGD;Acc:S000001440]" Bcin04g00450 820 "Bcrsp5, similar to yeast RSP5, E3 ubiquitin ligase of NEDD4 family; regulates many cellular processes including MVB sorting, heat shock response, transcription, endocytosis, ribosome stability; mutant tolerates aneuploidy; autoubiquitinates; ubiquitinates Sec23p and Sna3p; deubiquitinated by Ubp2p; activity regulated by SUMO ligase Siz1p, in turn regulates Siz1p SUMO ligase activity; required for efficient Golgi-to-ER trafficking in COPI mutants; human homolog implicated in Liddle syndrome [Source:SGD;Acc:S000000927]" Bcin04g00460 189 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcgpi, glycosylphosphatidylinositol (GPI)-anchored protein Bcin04g00470 236 CAZy : PL3PCW pectin//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1)//Early secretome Pectate lyase, catalytic + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin04g00480 366 Bcin04g00490 413 "Bcadh4, similar to yeast ADH4, Alcohol dehydrogenase isoenzyme type IV; dimeric enzyme demonstrated to be zinc-dependent despite sequence similarity to iron-activated alcohol dehydrogenases; transcription is induced in response to zinc deficiency [Source:SGD;Acc:S000003225]" Bcin04g00500 214 Bcin04g00510 307 Bcin04g00520 1474 Helicase, C-terminal + Helicase-associated domain + DEAD/DEAH box helicase domain + Domain of unknown function DUF1605 + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin04g00530 2673 "Bcgcn1, similar to yeast GCN1, Positive regulator of the Gcn2p kinase activity; forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA [Source:SGD;Acc:S000003163]" Bcin04g00540 194 Ribosomal protein L19/L19e domain + Ribosomal protein L19/L19e, domain 1 + Ribosomal protein L19/L19e, domain 2 + Ribosomal protein L19/L19e, domain 3 + Ribosomal protein L19/L19e conserved site Bcin04g00550 521 Serine hydroxymethyltransferase + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase + Serine hydroxymethyltransferase, pyridoxal phosphate binding site Bcin04g00560 196 Effector(V2)|Effector(V1) NADH dehydrogenase [ubiquinone] (complex I), 21kDa subunit, fungi Bcin04g00570 349 Bcprx1, Peroxiredoxin (AhpC/TSA family) Bcin04g00580 189 Effector(V2)|Effector(V1) PRELI/MSF1 Bcin04g00590 136 Bcin04g00600 237 Effector(V1) "Bcyfh7, similar to yeast YFH7, Putative kinase with similarity to the PRK/URK/PANK kinase subfamily; the PRK/URK/PANK subfamily of P-loop kinases is also known as phosphoribulokinase/uridine kinase/bacterial pantothenate kinase [Source:SGD;Acc:S000001903]" Bcin04g00610 414 Folylpolyglutamate synthetase + Mur ligase, C-terminal + Mur ligase, central Bcin04g00620 555 Effector(V1) Bcin04g00630 1445 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Armadillo-like helical + Armadillo-type fold + Protein kinase, ATP binding site Bcin04g00640 2657 SM cluster PKS20 (KE) Bcpks20, Polyketide synthase Bcin04g00650 474 SM cluster PKS20 Bcin04g00660 1561 Kinesin light chain + NB-ARC + Heterokaryon incompatibility + Tetratricopeptide-like helical domain + P-loop containing nucleoside triphosphate hydrolase Bcin04g00670 122 Effector(V2)|Effector(V1) Bcin04g00680 294 Bcin04g00690 235 Bcin04g00700 325 Homeodomain-like + Ribonuclease H-like domain + Winged helix-turn helix domain Bcin04g00710 300 Bcin04g00720 503 NB-ARC + Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase + P-loop containing nucleoside triphosphate hydrolase + Alpha/Beta hydrolase fold Bcin04g00730 454 Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Tetratricopeptide repeat Bcin04g00740 1298 Ankyrin repeat + Heterokaryon incompatibility + Ankyrin repeat-containing domain Bcin04g00750 944 Transporter P-type ATPase + Cation-transporting P-type ATPase, N-terminal + P-type ATPase, subfamily IIIA + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, transmembrane domain + P-type ATPase, cytoplasmic domain N Bcin04g00760 706 "Bcfaa2, similar to yeast FAA2, Medium chain fatty acyl-CoA synthetase; activates imported fatty acids; accepts a wide range of fatty acid chain lengths with a preference for medium chains, C9:0-C13:0; localized to the peroxisome [Source:SGD;Acc:S000000817]" Bcin04g00770 457 "Bcmet17, similar to yeast MET17, O-acetyl homoserine-O-acetyl serine sulfhydrylase; required for Methionine and cysteine biosynthesis [Source:SGD;Acc:S000004294]" Bcin04g00780 160 Marvel domain Bcin04g00790 1362 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat + P-loop containing nucleoside triphosphate hydrolase Bcin04g00800 1344 Ankyrin repeat + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin04g00810 365 Alpha/Beta hydrolase fold Bcin04g00820 325 Bcin04g00830 1508 WD40 repeat + NACHT nucleoside triphosphatase + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat + P-loop containing nucleoside triphosphate hydrolase + NWD NACHT-NTPase, N-terminal Bcin04g00840 274 Bcin04g00850 89 Effector(V1) Bcin04g00860 675 Caspase-like domain Bcin04g00870 1252 Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Tetratricopeptide repeat + CHAT domain Bcin04g00880 125 Effector(V1) Bcin04g00890 99 Effector(V2)|Effector(V1) Bcin04g00900 1846 Nucleoside phosphorylase domain + Ankyrin repeat + NACHT nucleoside triphosphatase + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin04g00910 406 Bcin04g00920 1023 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin04g00930 1263 Ankyrin repeat + Heterokaryon incompatibility + Ankyrin repeat-containing domain Bcin04g00940 1186 NB-ARC + Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Tetratricopeptide repeat + P-loop containing nucleoside triphosphate hydrolase + NACHT-NTPase and P-loop NTPases, N-terminal domain Bcin04g00950 1222 Ankyrin repeat + NACHT nucleoside triphosphatase + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase + NWD NACHT-NTPase, N-terminal Bcin04g00960 1673 P-loop containing nucleoside triphosphate hydrolase Bcin04g00970 471 Cys2His2 transcription factor JmjC domain + Zinc finger, BED-type + Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain Bcin04g00980 998 WD40 repeat + NACHT nucleoside triphosphatase + Heterokaryon incompatibility + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin04g00990 198 Effector(V2)|Effector(V1) Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin04g01000 393 Aminotransferases, class-I, pyridoxal-phosphate-binding site + Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin04g01010 161 Effector(V2)|Effector(V1) Bcin04g01020 1087 WD40 repeat + NACHT nucleoside triphosphatase + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat + P-loop containing nucleoside triphosphate hydrolase Bcin04g01030 1267 MIT Bcin04g01040 1370 "Bcoxp1, similar to yeast OXP1, 5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001698]" Bcin04g01050 650 "Bcsac6, similar to yeast SAC6, Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in the organization and maintenance of the actin cytoskeleton; relocalizes from plasma membrane to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000002536]" Bcin04g01060 153 Effector(V2)|Effector(V1) Phenylacetic acid degradation-related domain + Thioesterase superfamily + HotDog domain Bcin04g01070 253 Bcin04g01080 698 Membrane bound O-acyl transferase, MBOAT + Sterol O-acyltransferase, ACAT/DAG/ARE types Bcin04g01090 1226 Ankyrin repeat + Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB + Ankyrin repeat-containing domain Bcin04g01100 973 Bcin04g01110 70 Effector(V1) Bcin04g01120 1086 DDHD Bcin04g01130 204 Effector(V2)|Effector(V1) RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin04g01140 145 Effector(V2)|Effector(V1) Bcin04g01150 329 SignalP-noTM Thioredoxin-like fold + Oligosaccharyl transferase complex, subunit OST3/OST6 Bcin04g01160 737 Bcin04g01170 392 "Bcmrm2, similar to yeast MRM2, Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ [Source:SGD;Acc:S000003104]" Bcin04g01180 183 Ribosomal protein L18e + Ribosomal protein L18e/L15P + Ribosomal protein L18e, conserved site Bcin04g01190 327 Transporter Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin04g01200 381 Methyltransferase type 11 + Sterol methyltransferase C-terminal + S-adenosyl-L-methionine-dependent methyltransferase + SAM-dependent methyltransferase SMT-type Bcin04g01210 102 Effector(V2)|Effector(V1) Bcin04g01220 209 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Bcin04g01230 396 Bcin04g01240 529 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin04g01250 591 "Bcmcp2, similar to yeast MCP2, Mitochondrial protein of unknown function involved in lipid homeostasis; integral membrane protein that localizes to the mitochondrial inner membrane; involved in mitochondrial morphology; non-essential gene which interacts genetically with MDM10, and other members of the ERMES complex; transcription is periodic during the metabolic cycle; homologous to human aarF domain containing kinase, ADCK1 [Source:SGD;Acc:S000004243]" Bcin04g01260 164 Effector(V1) Bcin04g01270 404 Transporter Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin04g01280 124 Effector(V1) "Bcqcr7, similar to yeast QCR7, Subunit 7 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; oriented facing the mitochondrial matrix; N-terminus appears to play a role in complex assembly [Source:SGD;Acc:S000002937]" Bcin04g01290 405 CAZy : GT62 Nucleotide-diphospho-sugar transferases Bcin04g01300 479 "Bcmag1, similar to yeast MAG1, 3-methyl-adenine DNA glycosylase; involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000944]" Bcin04g01310 403 CAZy : GHnc //SignalP-noTM//Early secretome Leucine-rich repeat domain, L domain-like Bcin04g01320 513 "Bcpcs60, similar to yeast PCS60, Oxalyl-CoA synthetase; capable of catalyzing conversion of oxalate to oxalyl-CoA; catalyzes first step in pathway of oxalate degradation that functions to protect yeast from inhibitory effects of oxalate; peroxisomal protein that binds mRNA; localizes to both peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid; similar to E. coli long chain acyl-CoA synthetase [Source:SGD;Acc:S000000426]" Bcin04g01330 496 G-patch domain + RNA recognition motif domain + RNA recognition motif domain, eukaryote + Nucleotide-binding alpha-beta plait domain Bcin04g01340 360 Fatty acid hydroxylase Bcin04g01350 355 Fatty acid hydroxylase Bcin04g01360 504 Transporter Tetracycline resistance protein, TetA/multidrug resistance protein MdtG + Major facilitator superfamily + Major facilitator superfamily domain Bcin04g01370 361 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin04g01380 317 Pyrroline-5-carboxylate reductase + 6-phosphogluconate dehydrogenase C-terminal domain-like + NAD(P)-binding domain + Pyrroline-5-carboxylate reductase, catalytic, N-terminal + Pyrroline-5-carboxylate reductase, dimerisation domain Bcin04g01390 1314 SM cluster NRPS5 (KE) Bcnrps5, Nonribosomal peptide synthetase Bcin04g01400 253 SM cluster NRPS5//Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin04g01410 134 Effector(V1) Bcin04g01420 355 "Bcdre2, similar to yeast DRE2, Component of the cytosolic Fe-S protein assembly (CIA) machinery; contains an Fe-S cluster that receives electrons from NADPH via the action of Tah18pin an early step in the CIA pathway; ortholog of human Ciapin1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001779]" Bcin04g01430 211 Effector(V2)|Effector(V1) Bcin04g01440 437 "Bcice2, similar to yeast ICE2, Integral ER membrane protein with type-III transmembrane domains; required for maintenance of ER zinc homeostasis; necessary for efficient targeting of Trm1p tRNA methyltransferase to inner nuclear membrane; mutations cause defects in cortical ER morphology in both the mother and daughter cells [Source:SGD;Acc:S000001352]" Bcin04g01450 392 Metal-dependent protein hydrolase Bcin04g01460 164 Effector(V1) Endosulphine Bcin04g01470 205 "Bcsfm1, similar to yeast SFM1, SPOUT methyltransferase; catalyzes omega-monomethylation of Rps3p on Arg-146; not an essential gene; predicted to be involved in rRNA processing and ribosome biogenesis and in biopolymer catabolism [Source:SGD;Acc:S000005547]" Bcin04g01480 640 Protease//SignalP-noTM Peptidase S10, serine carboxypeptidase + Peptidase S10, serine carboxypeptidase, active site + Alpha/Beta hydrolase fold Bcin04g01490 360 "Bcgle2, similar to yeast GLE2, RNA export factor associated with the nuclear pore complex (NPC); associates with NUP116p; required for polyadenylated RNA export but not for protein import; homologous to S. pombe Rae1p and human RAE1 [Source:SGD;Acc:S000000909]" Bcin04g01500 472 Bcin04g01510 445 "Bcect1, similar to yeast ECT1, Ethanolamine-phosphate cytidylyltransferase; catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases [Source:SGD;Acc:S000003239]" Bcin04g01520 405 Aminotransferase, class IV + Branched-chain amino acid aminotransferase II Bcin04g01530 287 Bcin04g01540 262 Flavoprotein Bcin04g01550 151 Effector(V2)|Effector(V1) Bcgrx4, Glutaredoxin Bcin04g01560 292 Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin04g01570 780 Bcin04g01580 457 "Bcgcd7, similar to yeast GCD7, Beta subunit of the translation initiation factor eIF2B; the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression [Source:SGD;Acc:S000004282]" Bcin04g01590 505 "Bcnem1, similar to yeast NEM1, Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard [Source:SGD;Acc:S000001046]" Bcin04g01600 1471 "Bcrpo31, similar to yeast RPO31, RNA polymerase III largest subunit C160; part of core enzyme; similar to bacterial beta-prime subunit and to RPA190 and RPO21 [Source:SGD;Acc:S000005642]" Bcin04g01610 783 Neutral/alkaline nonlysosomal ceramidase + Neutral/alkaline non-lysosomal ceramidase, N-terminal + Neutral/alkaline non-lysosomal ceramidase, C-terminal Bcin04g01620 206 Effector(V1) Pre-mRNA-splicing factor SPF27 Bcin04g01630 468 yes Signaling pathway BcpkaR, Component of the cAMP cascade : PKA regulatory subunit Bcin04g01640 755 CAZy : CBM48 Immunoglobulin E-set + AMP-activated protein kinase, glycogen-binding domain Bcin04g01650 1023 Cys2His2 transcription factor Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin04g01660 542 Protease "Bcdug1, similar to yeast DUG1, Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p) [Source:SGD;Acc:S000001940]" Bcin04g01670 784 Protease Peptidase C19, ubiquitin carboxyl-terminal hydrolase + Zinc finger, UBP-type + UBA-like + Zinc finger, RING/FYVE/PHD-type + Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote + Ubiquitinyl hydrolase + Ubiquitin specific protease, conserved site + Ubiquitin specific protease domain Bcin04g01680 201 Effector(V2)|Effector(V1) NIF system FeS cluster assembly, NifU, N-terminal + ISC system FeS cluster assembly, IscU scaffold Bcin04g01690 603 "Bcdbp3, similar to yeast DBP3, RNA-Dependent ATPase, member of DExD/H-box family; involved in cleavage of site A3 within the ITS1 spacer during rRNA processing; not essential for growth, but deletion causes severe slow-growth phenotype [Source:SGD;Acc:S000003046]" Bcin04g01700 558 "Bcrft1, similar to yeast RFT1, Membrane protein required for translocation of Man5GlcNac2-PP-Dol; required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein; essential gene [Source:SGD;Acc:S000000116]" Bcin04g01710 283 SignalP-TM Bcin04g01720 476 "Bctpp1, similar to yeast TPP1, DNA 3'-phosphatase; functions in repair of endogenous damage of double-stranded DNA, activity is specific for removal of 3' phosphates at strand breaks; similar to the l-2-haloacid dehalogenase superfamily; homolog of human polynucleotide kinase/3′-phosphatase [Source:SGD;Acc:S000004765]" Bcin04g01730 113 Effector(V1) Bcin04g01740 551 Bcin04g01750 448 "Bcrtt106, similar to yeast RTT106, Histone chaperone; involved in regulation of chromatin structure in both transcribed and silenced chromosomal regions; affects transcriptional elongation; has a role in regulation of Ty1 transposition; interacts physically and functionally with Chromatin Assembly Factor-1 (CAF-1) [Source:SGD;Acc:S000005150]" Bcin04g01760 271 Target SNARE coiled-coil domain + Syntaxin, N-terminal domain + Syntaxin/epimorphin, conserved site + t-SNARE Bcin04g01770 657 Nucleoporin protein Ndc1-Nup Bcin04g01780 530 "Bcach1, similar to yeast ACH1, Protein with CoA transferase activity; particularly for CoASH transfer from succinyl-CoA to acetate; has minor acetyl-CoA-hydrolase activity; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth [Source:SGD;Acc:S000000111]" Bcin04g01790 78 Effector(V1) Bcin04g01800 236 Bcin04g01810 198 Bcin04g01820 163 Bcin04g01830 367 Kynurenine formamidase Bcin04g01840 712 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain Bcin04g01850 361 "Bcyvh1, similar to yeast YVH1, Protein phosphatase; involved in vegetative growth at low temperatures, sporulation, and glycogen accumulation; mutants are defective in 60S ribosome assembly; member of the dual-specificity family of protein phosphatases [Source:SGD;Acc:S000001465]" Bcin04g01860 184 VPS4-associated protein 1 Bcin04g01870 472 "Bcarg4, similar to yeast ARG4, Argininosuccinate lyase; catalyzes the final step in the arginine biosynthesis pathway [Source:SGD;Acc:S000001060]" Bcin04g01880 732 Bcin04g01890 382 "Bcmvd1, similar to yeast MVD1, Mevalonate pyrophosphate decarboxylase; essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer [Source:SGD;Acc:S000005326]" Bcin04g01900 282 "Bccyt2, similar to yeast CYT2, Cytochrome c1 heme lyase; involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1 [Source:SGD;Acc:S000001570]" Bcin04g01910 470 Root UVB sensitive family Bcin04g01920 136 Effector(V1) Ribosomal protein S36, mitochondrial Bcin04g01930 271 Mediator complex, subunit Med18, metazoa/fungi Bcin04g01940 78 Cytochrome c oxidase subunit VIIc Bcin04g01950 1084 Helicase, C-terminal + DEAD/DEAH box helicase domain + DSH, C-terminal + Helicase superfamily 1/2, ATP-binding domain + RNA helicase, ATP-dependent, SK12/DOB1 + rRNA-processing arch domain + P-loop containing nucleoside triphosphate hydrolase Bcin04g01960 1151 DENN domain + Protein kinase C-like, phorbol ester/diacylglycerol-binding domain + dDENN domain + uDENN domain Bcin04g01970 178 Bcin04g01980 634 SignalP-noTM Heterokaryon incompatibility Bcin04g01990 361 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin04g02000 606 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin04g02010 370 Bccat8, Catalase Bcin04g02020 590 "Bcrud3, similar to yeast RUD3, Golgi matrix protein; involved in the structural organization of the cis-Golgi; interacts genetically with COG3 and USO1 [Source:SGD;Acc:S000005742]" Bcin04g02030 352 Bcin04g02040 214 SignalP-noTM//Effector(V2) Get 1, fungi + WRB/Get1 family Bcin04g02050 345 Protein prenyltransferase, alpha subunit Bcin04g02060 579 Protease//SignalP-noTM Bcap13, Aspartic proteinase Bcin04g02070 394 Bcin04g02080 123 Effector(V1) Bcin04g02090 1116 "Bcufd2, similar to yeast UFD2, Ubiquitin chain assembly factor (E4); cooperates with a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), and a ubiquitin protein ligase (E3) to conjugate ubiquitin to substrates; also functions as an E3 [Source:SGD;Acc:S000002349]" Bcin04g02100 356 DnaJ domain + Domain of unknown function DUF1977, DnaJ-like Bcin04g02110 140 Effector(V2)|Effector(V1) Bcin04g02120 314 "Bcsiw14, similar to yeast SIW14, Tyrosine phosphatase involved in actin organization and endocytosis; localized to the cytoplasm [Source:SGD;Acc:S000004977]" Bcin04g02130 659 Ima1, N-terminal domain Bcin04g02140 257 CAZy : GT1 "Bcalg14, similar to yeast ALG14, Component of UDP-GlcNAc transferase; required for the second step of dolichyl-linked oligosaccharide synthesis; anchors the catalytic subunit Alg13p to the ER membrane; similar to bacterial and human glycosyltransferases [Source:SGD;Acc:S000000274]" Bcin04g02150 241 "Bcrsm25, similar to yeast RSM25, Mitochondrial ribosomal protein of the small subunit [Source:SGD;Acc:S000001355]" Bcin04g02160 599 Pentatricopeptide repeat Bcin04g02170 120 Protein kinase-like domain Bcin04g02180 73 Bcin04g02190 892 Protein of unknown function DUF3712 Bcin04g02200 323 "Bcilv6, similar to yeast ILV6, Regulatory subunit of acetolactate synthase; acetolactate synthase catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria [Source:SGD;Acc:S000000515]" Bcin04g02210 486 K Homology domain + K Homology domain, type 1 Bcin04g02220 181 SET domain Bcin04g02230 376 Protein of unknown function DUF974 Bcin04g02240 338 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + NAD(P)-binding domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Bcin04g02250 415 NADH:flavin oxidoreductase/NADH oxidase, N-terminal + Aldolase-type TIM barrel Bcin04g02260 245 Bcebp4, Emopamil-binding protein Bcin04g02270 378 Bcin04g02280 497 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin04g02290 682 Bcin04g02300 377 Bcin04g02310 398 SignalP-noTM Purine nucleoside permease Bcin04g02320 492 Bcin04g02330 412 Bcin04g02340 154 Marvel domain Bcin04g02350 684 Bcin04g02360 513 Voltage-dependent anion channel + Malic acid transport protein Bcin04g02370 878 SAP domain Bcin04g02380 489 Protease Amidohydrolase 1 + Metal-dependent hydrolase, composite domain + Metal-dependent hydrolase Bcin04g02390 402 SignalP-TM Six-bladed beta-propeller, TolB-like + SMP-30/Gluconolactonase/LRE-like region Bcin04g02400 240 Effector(V1) O-methyltransferase, family 3 + S-adenosyl-L-methionine-dependent methyltransferase Bcin04g02410 376 Peroxisome membrane anchor protein Pex14p, N-terminal + Peroxisomal membrane protein 14 Bcin04g02420 426 INO80 complex subunit B-like conserved region + INO80 complex, subunit Ies2 Bcin04g02430 172 Bcin04g02440 500 Bcin04g02450 128 Effector(V1) Bcin04g02460 460 SignalP-noTM Phosphoesterase Bcin04g02470 858 Sodium/sulphate symporter + SPX, N-terminal Bcin04g02480 181 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin04g02490 703 Protease Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin04g02500 455 NADP-dependent oxidoreductase domain Bcin04g02510 563 Transporter Amino acid permease/ SLC12A domain + Amino acid/polyamine transporter I + Amino acid permease, conserved site Bcin04g02520 466 CAZy : CBM1,CE16PCW hemicellulose//SignalP-noTM Cellulose-binding domain, fungal + SGNH hydrolase-type esterase domain Bcin04g02530 273 Bcin04g02540 513 Bestrophin/UPF0187 Bcin04g02550 314 Bcin04g02560 212 Effector(V2) Bcin04g02570 105 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin04g02580 308 Bcin04g02590 216 Effector(V1) Bcin04g02600 464 Major facilitator superfamily + Major facilitator superfamily domain Bcin04g02610 215 Effector(V2)|Effector(V1) Bcin04g02620 110 Effector(V1) Bcin04g02630 262 Bcin04g02640 405 Bcin04g02650 611 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin04g02660 665 Glycoside hydrolase family 31 + Galactose mutarotase-like domain + Aldolase-type TIM barrel + Glycoside hydrolase superfamily Bcin04g02670 566 Transporter General substrate transporter + Major facilitator superfamily domain Bcin04g02680 578 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin04g02690 248 SignalP-noTM Bcin04g02700 312 Bcin04g02710 663 Bcin04g02720 391 Protein of unknown function DUF3984 Bcin04g02730 1335 "Bciki3, similar to yeast IKI3, Subunit of Elongator complex; Elongator is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD) [Source:SGD;Acc:S000004376]" Bcin04g02740 393 KOW + Ribosomal protein L24/L26, conserved site + Translation protein SH3-like domain + Ribosomal protein L2 domain 2 Bcin04g02750 192 Effector(V2)|Effector(V1) "Bcrho1, similar to yeast RHO1, GTP-binding protein of the rho subfamily of Ras-like proteins; involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p) [Source:SGD;Acc:S000006369]" Bcin04g02760 75 Effector(V1) Bcin04g02770 1359 Bcin04g02780 465 Bcin04g02790 2047 SNF2-related + Helicase, C-terminal + Zinc finger, PHD-type + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Helicase superfamily 1/2, ATP-binding domain + Chromo domain-like + P-loop containing nucleoside triphosphate hydrolase Bcin04g02800 654 tRNA/rRNA methyltransferase, SpoU type + RNA methyltransferase TrmH family + RNA 2-O ribose methyltransferase, substrate binding + tRNA (guanine-N1-)-methyltransferase, N-terminal + Alpha/beta knot methyltransferases + 50S ribosomal protein L30e-like Bcin04g02810 379 "Bcarp1, similar to yeast ARP1, Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; forms actin-like short filament composed of 9 or 10 Arp1p monomers; putative ortholog of mammalian centractin [Source:SGD;Acc:S000001171]" Bcin04g02820 47 Effector(V1) Bcin04g02830 493 Bcin04g02840 451 Bcin04g02850 259 Bcin04g02860 284 Bcin04g02870 533 Domain of unknown function DUF4050 Bcin04g02880 173 Bcin04g02890 389 RGS domain Bcin04g02900 229 Effector(V1) Bcin04g02910 142 Effector(V1) Bcin04g02920 323 Bcin04g02930 1412 Transporter Bmr5, ABC-transporter Bcin04g02940 365 Zn2/Cys6 transcription factor Bcin04g02950 271 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin04g02960 409 "Bcaim22, similar to yeast AIM22, Putative lipoate-protein ligase; required along with Lip2 and Lip5 for lipoylation of Lat1p and Kgd2p; similar to E. coli LplA; null mutant displays reduced frequency of mitochondrial genome loss [Source:SGD;Acc:S000003582]" Bcin04g02970 442 "Bcaro2, similar to yeast ARO2, Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003116]" Bcin04g02980 1032 Heterokaryon incompatibility Bcin04g02990 1571 Bcin04g03000 255 3'-5' exonuclease domain + Ribonuclease H-like domain Bcin04g03010 539 Transporter "Bcavt2, similar to yeast AVT2, Putative transporter; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters [Source:SGD;Acc:S000000790]" Bcin04g03020 429 "Bcnop15, similar to yeast NOP15, Constituent of 66S pre-ribosomal particles; involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm [Source:SGD;Acc:S000005054]" Bcin04g03030 335 "Bctif34, similar to yeast TIF34, eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3); subunit of the core complex of eIF3; essential for translation; stimulates rate of ribosomal scanning during translation reinitiation [Source:SGD;Acc:S000004754]" Bcin04g03040 1048 Formate-tetrahydrofolate ligase, FTHFS + Tetrahydrofolate dehydrogenase/cyclohydrolase + NAD(P)-binding domain + Formate-tetrahydrofolate ligase, FTHFS, conserved site + Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain + Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain + Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin04g03050 398 Signaling pathway Bcgpr5, G protein-coupled receptor 5 Bcin04g03060 727 "Bctrp5, similar to yeast TRP5, Tryptophan synthase; catalyzes the last step of tryptophan biosynthesis; regulated by the general control system of amino acid biosynthesis [Source:SGD;Acc:S000002994]" Bcin04g03070 159 Effector(V1) Protein of unknown function DUF1674 Bcin04g03080 377 Bcin04g03090 413 Tryptophan synthase beta subunit-like PLP-dependent enzyme Bcin04g03100 398 "Bcilv5, similar to yeast ILV5, Acetohydroxyacid reductoisomerase and mtDNA binding protein; involved in branched-chain amino acid biosynthesis and maintenance of wild-type mitochondrial DNA; found in mitochondrial nucleoids [Source:SGD;Acc:S000004347]" Bcin04g03110 185 Effector(V2)|Effector(V1) "Bcubc12, similar to yeast UBC12, Enzyme that mediates the conjugation of Rub1p; a ubiquitin-like protein, to other proteins; related to E2 ubiquitin-conjugating enzymes [Source:SGD;Acc:S000004297]" Bcin04g03120 911 yes CAZy : GT2 BcCHSIIIa, Chitin synthase Bcin04g03130 392 Membrane anchor Opy2, N-terminal Bcin04g03140 232 yes Effector(V2)|Effector(V1)//Signaling pathway Bcras2, Ras-like GTPase Bcin04g03150 700 AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain + Acetyl-coenzyme A synthetase, N-terminal domain Bcin04g03160 1391 Pleckstrin homology domain, Mcp5-type Bcin04g03170 399 Bcin04g03190 1867 Bcin04g03200 558 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin04g03210 237 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin04g03220 769 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin04g03230 262 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin04g03240 275 TPMT family + S-adenosyl-L-methionine-dependent methyltransferase Bcin04g03250 303 Protease "Bcotu2, similar to yeast OTU2, Protein of unknown function; may interact with ribosomes, based on co-purification experiments; member of the ovarian tumor-like (OTU) superfamily of predicted cysteine proteases; shows cytoplasmic localization; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001005]" Bcin04g03260 174 RmlC-like cupin domain + RmlC-like jelly roll fold Bcin04g03270 310 RTA-like protein Bcin04g03280 583 Cys2His2 transcription factor Zinc finger, C2H2-like Bcin04g03290 606 Heat shock protein 70 family Bcin04g03300 536 Bcin04g03310 336 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + Quinone oxidoreductase PIG3 + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin04g03320 265 Effector(V1) "Bcnrk1, similar to yeast NRK1, Nicotinamide riboside kinase; catalyzes the phosphorylation of nicotinamide riboside and nicotinic acid riboside in salvage pathways for NAD+ biosynthesis [Source:SGD;Acc:S000005073]" Bcin04g03330 426 Bcpio13, Gene with a peak of expression during the Outset of colonization Bcin04g03340 344 Bcin04g03350 157 Effector(V1) Bcin04g03360 288 Protein of unknown function DUF4646 Bcin04g03370 704 RNA ligase domain, REL/Rln2 Bcin04g03380 492 Macro domain Bcin04g03390 450 SPX, N-terminal Bcin04g03400 755 "Bcmpp10, similar to yeast MPP10, Component of the SSU processome and 90S preribosome; required for pre-18S rRNA processing, interacts with and controls the stability of Imp3p and Imp4p, essential for viability; similar to human Mpp10p [Source:SGD;Acc:S000003762]" Bcin04g03410 685 ATPase, AFG1-like + P-loop containing nucleoside triphosphate hydrolase Bcin04g03420 1396 "Bcnup133, similar to yeast NUP133, Subunit of Nup84p subcomplex of nuclear pore complex (NPC); contributes to nucleocytoplasmic transport, NPC biogenesis; is involved in establishment of a normal nucleocytoplasmic concentration gradient of GTPase Gsp1p; also plays roles in several processes that may require localization of genes or chromosomes at nuclear periphery, including double-strand break repair, transcription and chromatin silencing; relocalizes to cytosol in response to hypoxia; homolog of human NUP133 [Source:SGD;Acc:S000001790]" Bcin04g03430 449 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin04g03440 224 SignalP-noTM//Effector(V2) GOLD + TMP21-related Bcin04g03450 608 SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 + DAMP1, SANT/Myb-like domain Bcin04g03460 332 SignalP-noTM Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin04g03470 346 Protein kinase domain + Protein kinase-like domain Bcin04g03480 473 Heterokaryon incompatibility Bcin04g03490 794 yes Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Bacterial transferase hexapeptide repeat + Trimeric LpxA-like + Maltose/galactoside acetyltransferase Bcin04g03500 128 Bcin04g03510 348 SignalP-noTM RlpA-like double-psi beta-barrel domain Bcin04g03520 902 Protein of unknown function DUF1712, fungi Bcin04g03530 445 "Bcfmt1, similar to yeast FMT1, Methionyl-tRNA formyltransferase; catalyzes the formylation of initiator Met-tRNA in mitochondria; potential Cdc28p substrate [Source:SGD;Acc:S000000109]" Bcin04g03540 295 SM cluster STC4 Domain of unknown function SprT-like Bcin04g03550 441 SM cluster STC4 (KE) Bcstc4, Sesquiterpen cyclase Bcin04g03560 115 Effector(V2)|Effector(V1) Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin04g03570 629 Protein of unknown function DUF3176 Bcin04g03580 632 "Bcgus1, similar to yeast GUS1, Glutamyl-tRNA synthetase (GluRS); forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003214]" Bcin04g03590 316 "Bcmrpl1, similar to yeast MRPL1, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000002523]" Bcin04g03600 289 COG complex component, COG2 + Conserved oligomeric Golgi complex, subunit 2, N-terminal Bcin04g03610 511 Bzip transcription factor Basic-leucine zipper domain + Hap4 transcription factor, heteromerisation domain + Microtubule-associated protein RP/EB Bcin04g03620 341 SignalP-noTM//Early secretome Ribonuclease T2-like + Ribonuclease T2, active site + Ribonuclease T2, His active site 2 Bcin04g03630 335 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin04g03640 338 Bcin04g03650 194 Effector(V2)|Effector(V1) Alpha-ketoglutarate-dependent dioxygenase AlkB-like Bcin04g03660 669 "Bcvma1, similar to yeast VMA1, Subunit A of the V1 peripheral membrane domain of V-ATPase; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits; involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner [Source:SGD;Acc:S000002344]" Bcin04g03670 600 "Bcgid7, similar to yeast GID7, Subunit of GID Complex that binds directly to central component Vid30p; GID complex is involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; Gid7p contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions [Source:SGD;Acc:S000000544]" Bcin04g03680 346 "Bcrbk1, similar to yeast RBK1, Putative ribokinase [Source:SGD;Acc:S000000632]" Bcin04g03690 695 "Bcvps1, similar to yeast VPS1, Dynamin-like GTPase required for vacuolar sorting; also involved in actin cytoskeleton organization, endocytosis, late Golgi-retention of some proteins, regulation of peroxisome biogenesis [Source:SGD;Acc:S000001709]" Bcin04g03700 82 Bcin04g03710 404 CoA-transferase family III + CoA-transferase family III domain Bcin04g03720 397 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin04g03730 576 Bcin04g03740 172 Bcin04g03750 511 Transporter Amino acid/polyamine transporter I Bcin04g03760 450 Zinc finger, CCHC-type Bcin04g03770 446 "Bcapm1, similar to yeast APM1, Mu1-like medium subunit of the AP-1 complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; the AP-1 complex is the clathrin-associated protein complex [Source:SGD;Acc:S000006180]" Bcin04g03780 75 Effector(V2) Bcin04g03790 573 Transcription factor Opi1 Bcin04g03800 664 Bcin04g03810 255 Bcin04g03820 175 Effector(V2)|Effector(V1) Bcin04g03830 455 Bcin04g03840 484 "Bcugo1, similar to yeast UGO1, Outer membrane component of the mitochondrial fusion machinery; binds directly to Fzo1p and Mgm1p and thus links these two GTPases during mitochondrial fusion; involved in fusion of both the outer and inner membranes; facilitates dimerization of Fzo1p during fusion; import into the outer membrane is mediated by Tom70p and Mim1p; has similarity to carrier proteins but is not likely to function as a transmembrane transporter [Source:SGD;Acc:S000002878]" Bcin04g03850 213 Effector(V2)|Effector(V1) "Bcyah1, similar to yeast YAH1, Ferredoxin of the mitochondrial matrix; required for formation of cellular iron-sulfur proteins; involved in heme A biosynthesis; homologous to human adrenodoxin [Source:SGD;Acc:S000006173]" Bcin04g03860 291 "Bcrrp15, similar to yeast RRP15, Nucleolar protein; constituent of pre-60S ribosomal particles; required for proper processing of the 27S pre-rRNA at the A3 and B1 sites to yield mature 5.8S and 25S rRNAs [Source:SGD;Acc:S000006347]" Bcin04g03870 529 "Bcsrp54, similar to yeast SRP54, Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain [Source:SGD;Acc:S000006292]" Bcin04g03880 415 Bcin04g03890 366 Oxidoreductase, N-terminal + NAD(P)-binding domain Bcin04g03900 404 SignalP-noTM Bcin04g03910 428 Bcin04g03920 213 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin04g03930 846 Bcin04g03940 314 Pyridine nucleotide-disulphide oxidoreductase, class-II + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin04g03950 572 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin04g03960 263 "Bcglc8, similar to yeast GLC8, Regulatory subunit of protein phosphatase 1 (Glc7p); involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004928]" Bcin04g03970 1213 "Bcret1, similar to yeast RET1, Second-largest subunit of RNA polymerase III; RNA polymerase III is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs [Source:SGD;Acc:S000005733]" Bcin04g03980 1030 Pumilio RNA-binding repeat + Armadillo-like helical + Armadillo-type fold + Pumilio homology domain Bcin04g03990 575 Transporter Phosphate permease + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin04g04000 393 CMP/dCMP deaminase, zinc-binding + Cytidine deaminase-like Bcin04g04010 1031 Armadillo + Armadillo-like helical + Armadillo-type fold Bcin04g04020 383 "Bcpho80, similar to yeast PHO80, Cyclin; interacts with cyclin-dependent kinase Pho85p; regulates the response to nutrient levels and environmental conditions, including the response to phosphate limitation and stress-dependent calcium signaling [Source:SGD;Acc:S000005361]" Bcin04g04030 206 SignalP-noTM Bcin04g04040 428 "Bcyea4, similar to yeast YEA4, Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter; required for cell wall chitin synthesis; localized to the ER [Source:SGD;Acc:S000000730]" Bcin04g04050 161 Effector(V1) Bcin04g04060 238 SignalP-noTM Domain of unknown function DUF2012 Bcin04g04070 210 Bcccg2, Homologue of N. crassa clock-controlled gene-2 Bcin04g04080 557 Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin04g04090 231 "Bcard1, similar to yeast ARD1, Subunit of protein N-terminal acetyltransferase NatA; NatA is comprised of Nat1p, Ard1p, and Nat5p; acetylates many proteins and thus affects telomeric silencing, cell cycle, heat-shock resistance, mating, and sporulation; human Ard1p levels are elevated in cancer cells; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001055]" Bcin04g04100 283 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin04g04110 315 Bcin04g04120 2545 IQ motif, EF-hand binding site Bcin04g04130 226 "Bcsnf7, similar to yeast SNF7, One of four subunits of the ESCRT-III complex; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes; ESCRT-III stands for endosomal sorting complex required for transport III [Source:SGD;Acc:S000004015]" Bcin04g04140 128 Effector(V2)|Effector(V1) CST complex subunit Ten1, fungal Bcin04g04150 115 Effector(V1) Bcin04g04160 1264 Fork head transcription factor Forkhead-associated (FHA) domain + Transcription factor, fork head + SMAD/FHA domain + Winged helix-turn-helix DNA-binding domain + Fork head domain conserved site 2 Bcin04g04170 77 Effector(V2)|Effector(V1) Bcin04g04180 664 SART-1 protein Bcin04g04190 672 CAZy : GH15,CBM20Energy //Early secretome BcGs1, glycoprotein that elicits defence response and improves disease resistance in host plants (Zhang et al., 2015) Bcin04g04200 191 Transcriptional coactivator p15 (PC4) + ssDNA-binding transcriptional regulator Bcin04g04210 1039 Phox homologous domain + Phox-associated domain + Sorting nexin, C-terminal Bcin04g04220 252 "Bcmad2, similar to yeast MAD2, Component of the spindle-assembly checkpoint complex; delays onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p; regulates APC/C activity during prometaphase and metaphase of meiosis I; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability [Source:SGD;Acc:S000003567]" Bcin04g04230 657 "Bcguf1, similar to yeast GUF1, Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor [Source:SGD;Acc:S000004280]" Bcin04g04240 506 Peroxin/Ferlin domain Bcin04g04250 133 Effector(V1) Bcin04g04260 642 Aminoacyl-tRNA synthetase, class I, conserved site + Aminoacyl-tRNA synthetase, class 1a, anticodon-binding + Rossmann-like alpha/beta/alpha sandwich fold + Methionyl-tRNA synthetase + Methionyl/Leucyl tRNA synthetase + Methionyl-tRNA synthetase, Zn-domain + Methioninyl-tRNA synthetase core domain Bcin04g04270 180 Effector(V1) Essential protein Yae1, N-terminal Bcin04g04280 486 Uncharacterised protein family UPF0662 Bcin04g04290 110 Ribosomal protein L12 family Bcin04g04300 147 Effector(V2)|Effector(V1) YCII-related + Dimeric alpha-beta barrel Bcin04g04310 673 Zinc finger, SWIM-type + Zinc finger, RING/FYVE/PHD-type Bcin04g04320 368 "Bcarg3, similar to yeast ARG3, Ornithine carbamoyltransferase; also known as carbamoylphosphate:L-ornithine carbamoyltransferase; catalyzes the biosynthesis of the arginine precursor citrulline [Source:SGD;Acc:S000003624]" Bcin04g04330 154 Bcin04g04340 287 Bcin04g04350 573 Transporter "Bcdip5, similar to yeast DIP5, Dicarboxylic amino acid permease; mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly; relocalizes from plasma membrane to vacuole upon DNA replication stress [Source:SGD;Acc:S000006186]" Bcin04g04360 808 "Bcaco2, similar to yeast ACO2, Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol [Source:SGD;Acc:S000003736]" Bcin04g04370 1241 Bcin04g04380 601 Tetratricopeptide-like helical domain Bcin04g04390 393 Bcin04g04400 301 "Bcsts1, similar to yeast STS1, Protein required for localizing proteasomes to the nucleus; involved in cotranslational protein degradation; mediates interaction between nuclear import factor Srp1p and the proteasome; Sts1p and Srp1p couple proteasomes to nascent polypeptides emerging from the ribosome for cotranslational degradation; involved in ubiquitin-mediated protein degradation [Source:SGD;Acc:S000001450]" Bcin04g04410 572 "Bcrad52, similar to yeast RAD52, Protein that stimulates strand exchange; stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis and UV induced sister chromatid recombination [Source:SGD;Acc:S000004494]" Bcin04g04420 317 Cys2His2 transcription factor//Protease Zinc finger, C2H2 + UBA-like + Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote + Ubiquitin-related domain Bcin04g04430 300 "Bcscs2, similar to yeast SCS2, Integral ER membrane protein, regulates phospholipid metabolism; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to the plasma membrane (PM) and regulate PI4P levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; interacts with FFAT motif of Opi1p; involved in telomeric silencing; null shows inositol auxotrophy above 34 deg C; VAP homolog; SCS2 has a paralog, SCS22, that arose from the whole genome duplication [Source:SGD;Acc:S000000922]" Bcin04g04440 382 Fatty acid desaturase, type 1 + Sphingolipid delta4-desaturase + Sphingolipid delta4-desaturase, N-terminal Bcin04g04450 455 Hydroxymethylglutaryl-CoA synthase, eukaryotic + Hydroxymethylglutaryl-coenzyme A synthase, N-terminal + Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain + Thiolase-like Bcin04g04460 315 Bcin04g04470 336 "Bcpex19, similar to yeast PEX19, Chaperone and import receptor for newly-synthesized class I PMPs; binds peroxisomal membrane proteins (PMPs) in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane; interacts with Myo2p and contributes to peroxisome partitioning [Source:SGD;Acc:S000002223]" Bcin04g04480 158 Effector(V2)|Effector(V1) "Bcubc9, similar to yeast UBC9, SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC) [Source:SGD;Acc:S000002222]" Bcin04g04490 581 Protease Asparagine synthase + Asparagine synthase, glutamine-hydrolyzing + Rossmann-like alpha/beta/alpha sandwich fold + Glutamine amidotransferase type 2 domain + Nucleophile aminohydrolases, N-terminal Bcin04g04500 283 Effector(V2) Porin, eukaryotic type + Porin domain + Eukaryotic porin/Tom40 Bcin04g04510 268 DnaJ domain Bcin04g04520 448 Protease Peptidase M24, structural domain + Peptidase M24, methionine aminopeptidase + Peptidase M24A, methionine aminopeptidase, subfamily 2 + Winged helix-turn-helix DNA-binding domain Bcin04g04530 245 Bcin04g04540 187 Bcin04g04550 445 Diphthamide synthesis DPH1/DPH2 Bcin04g04560 425 F-box domain Bcin04g04570 158 Bcin04g04580 498 Major facilitator superfamily + Major facilitator superfamily domain Bcin04g04590 452 SignalP-noTM Phosphoesterase Bcin04g04600 471 "Bcyhc3, similar to yeast YHC3, Protein required for the ATP-dependent transport of arginine; vacuolar membrane protein; involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; homolog of human CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis) [Source:SGD;Acc:S000003595]" Bcin04g04610 1354 Histone deacetylation protein Rxt3 Bcin04g04620 792 "Bcama1, similar to yeast AMA1, Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis; prevents premature assembly of the meiosis I spindle, required for DSB induced prophase I arrest [Source:SGD;Acc:S000003457]" Bcin04g04630 406 "Bcbet4, similar to yeast BET4, Alpha subunit of Type II geranylgeranyltransferase; required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p [Source:SGD;Acc:S000003568]" Bcin04g04640 228 Bcin04g04650 163 Effector(V2)|Effector(V1) Bcin04g04660 134 Effector(V1) Bcin04g04670 229 Bcin04g04680 289 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin04g04690 213 Bcin04g04700 192 Effector(V2)|Effector(V1) Heterokaryon incompatibility Bcin04g04710 281 Bcin04g04720 290 Bcin04g04730 154 Bcin04g04740 495 Bcin04g04750 225 Major facilitator superfamily domain Bcin04g04760 125 SignalP-noTM Bcin04g04770 490 "Bcarg8, similar to yeast ARG8, Acetylornithine aminotransferase; catalyzes the fourth step in the biosynthesis of the arginine precursor ornithine [Source:SGD;Acc:S000005500]" Bcin04g04780 663 Heterokaryon incompatibility Bcin04g04790 322 S-adenosyl-L-methionine-dependent methyltransferase Bcin04g04800 289 yes SM cluster Melanin ter//Effector(V2)|Effector(V1) Bcbrn1, Tetrahydroxynaphtalene (THN) reductase, involved in DHN melanin biosynthesis Bcin04g04810 376 Pyruvate carboxyltransferase + Aldolase-type TIM barrel Bcin04g04820 517 "Bcvma2, similar to yeast VMA2, Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase; an electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000331]" Bcin04g04830 426 SignalP-noTM//Early secretome Aldose 1-/Glucose-6-phosphate 1-epimerase + Galactose mutarotase-like domain + Glycoside hydrolase-type carbohydrate-binding, subgroup Bcin04g04840 1012 Protein kinase domain + Protein kinase-like domain Bcin04g04850 875 MHYT Bcin04g04860 333 Bcin04g04870 74 Bcin04g04880 650 FAD-binding 8 + Ferric reductase, NAD binding + Ferric reductase transmembrane component-like domain + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel Bcin04g04890 171 Bcin04g04900 964 SignalP-noTM Bromodomain Bcin04g04910 187 Effector(V1) Bcin04g04920 342 Bcnmt1, Thiaminesynthase Bcin04g04930 514 CAZy : GH28PCW pectin//SignalP-noTM//Early secretome BcPG3, Endopolygalacturonase Bcin04g04940 146 Bcin04g04950 386 Bcin04g04960 185 Bcin04g04970 228 Effector(V2) Domain of unknown function DUF2470 Bcin04g04980 2068 SH3 domain + Dedicator of cytokinesis C-terminal + Armadillo-type fold + Dedicator of cytokinesis + DHR-1 domain + DHR-2 domain + DOCK-like protein YLR422W + Dedicator of cytokinesis, N-terminal domain Bcin04g04990 218 Bcin04g05000 1153 BcppoA90, Fatty acid oxygenase Bcin04g05010 319 "Bctsc13, similar to yeast TSC13, Enoyl reductase; catalyzes the last step in each cycle of very long chain fatty acid elongation; localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions; coimmunoprecipitates with elongases Fen1p and Sur4p; protein increases in abundance and relative distribution to ER foci increases upon DNA replication stress [Source:SGD;Acc:S000002173]" Bcin04g05020 398 yes SignalP-noTM Bcflp1, Fasciclin-like protein Bcin04g05030 1334 "Bcnip100, similar to yeast NIP100, Large subunit of the dynactin complex; dynactin is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued) [Source:SGD;Acc:S000006095]" Bcin04g05040 953 Rab-GTPase-TBC domain Bcin04g05050 4222 HECT + UBA-like + E3 ubiquitin ligase, domain of unknown function DUF908 + E3 ubiquitin ligase, domain of unknown function DUF913 + Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote + Domain of unknown function DUF4414 Bcin04g05060 321 Phosphoribosyl pyrophosphate synthetase, conserved site + Ribose-phosphate diphosphokinase + Phosphoribosyltransferase-like + Ribose-phosphate pyrophosphokinase, N-terminal domain Bcin04g05070 239 Ribosomal protein S6e + Ribosomal protein S6, eukaryotic + Ribosomal protein S6e, conserved site Bcin04g05080 166 Chromosome transmission fidelity protein 8 Bcin04g05090 245 SignalP-TM Bcin04g05100 323 Bcin04g05110 345 Aldo/keto reductase, conserved site + NADP-dependent oxidoreductase domain Bcin04g05120 1010 Ankyrin repeat + NACHT nucleoside triphosphatase + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin04g05130 713 "Bcpxa2, similar to yeast PXA2, Subunit of a heterodimeric peroxisomal ABC transport complex; required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter ABCD1 and ABCD2 and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; complex also includes Pxa1p [Source:SGD;Acc:S000001671]" Bcin04g05140 372 SignalP-noTM Bcin04g05150 454 "Bcfbp26, similar to yeast FBP26, Fructose-2,6-bisphosphatase, required for glucose metabolism; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003691]" Bcin04g05160 405 Bcin04g05170 192 Effector(V2)|Effector(V1) Outer membrane protein/outer membrane enzyme PagP, beta-barrel + Uncharacterised protein family UPF0311 Bcin04g05180 281 GCN5-like 1 Bcin04g05190 204 Ribosomal protein S8e + Ribosomal protein S8e/ribosomal biogenesis NSA2 Bcin04g05200 310 BTB/POZ fold Bcin04g05210 548 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin04g05220 81 "Bckti11, similar to yeast KTI11, Zn-ribbon protein that co-purifies with Dph1 and Dph2; in a complex required for synthesis of diphthamide on translation factor eEF2 and with Elongator subunits Iki3p, Elp2p, and Elp3p; involved in modification of wobble nucleosides in tRNAs [Source:SGD;Acc:S000007587]" Bcin04g05230 204 "Bcyfh1, similar to yeast YFH1, Mitochondrial matrix iron chaperone; oxidizes and stores iron; interacts with Isu1p to promote Fe-S cluster assembly; mutation results in multiple Fe/S-dependent enzyme deficiencies; human frataxin homolog is mutated in Friedrich's ataxia [Source:SGD;Acc:S000002278]" Bcin04g05240 187 Effector(V2)|Effector(V1) "Bcaps3, similar to yeast APS3, Small subunit of the clathrin-associated adaptor complex AP-3; involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003561]" Bcin04g05250 139 Bcin04g05260 1124 "Bccdc60, similar to yeast CDC60, Cytosolic leucyl tRNA synthetase; ligates leucine to the appropriate tRNA [Source:SGD;Acc:S000006081]" Bcin04g05270 499 SignalP-noTM Bcin04g05280 299 Phosphoglycerate/bisphosphoglycerate mutase, active site + Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin04g05290 1101 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin04g05300 501 yes Bcglr1, Glutathione reductase Bcin04g05310 364 SAP domain + Ribonuclease H-like domain + Mitochondrial resolvase Ydc2, catalytic Bcin04g05320 782 "Bccex1, similar to yeast CEX1, Component of nuclear aminoacylation-dependent tRNA export pathway; cytoplasmic; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a; required for activation of RAN GTPase Gsp1p and dissociation of receptor-tRNA-Gsp1p export complex; recruits Rna1p from cytoplasm to NPC, facilitates Rna1p activation of Gsp1p GTPase activity by enabling Rna1p to gain access to Gsp1p-GTP bound to export receptor tRNA complex [Source:SGD;Acc:S000005638]" Bcin04g05330 729 Zinc finger, PHD-type + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type Bcin04g05340 144 Effector(V2)|Effector(V1) Bcin04g05350 480 Helicase, C-terminal + DNA helicase, ATP-dependent, RecQ type + DEAD/DEAH box helicase domain + Winged helix-turn-helix DNA-binding domain + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase + ATP-dependent DNA helicase RecQ, zinc-binding domain Bcin04g05360 938 "Bcsog2, similar to yeast SOG2, Key component of the RAM signaling network; required for proper cell morphogenesis and cell separation after mitosis [Source:SGD;Acc:S000005880]" Bcin04g05370 691 "Bcsok1, similar to yeast SOK1, Protein of unknown function; overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13 [Source:SGD;Acc:S000002413]" Bcin04g05380 1258 Bcin04g05390 436 "Bccia1, similar to yeast CIA1, Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at a late step of Fe-S cluster assembly; forms the CIA targeting complex with Cia2p and Met18p that directs Fe-S cluster incorporation into a subset of proteins involved in methionine biosynthesis, DNA replication and repair, transcription, and telomere maintenance; contains WD40 repeats; ortholog of human Ciao1 protein [Source:SGD;Acc:S000002675]" Bcin04g05400 459 Bcin04g05410 715 Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A Bcin04g05420 148 Effector(V2)|Effector(V1) Bcin04g05430 541 SignalP-noTM PLC-like phosphodiesterase, TIM beta/alpha-barrel domain Bcin04g05440 145 Effector(V2)|Effector(V1) Ribosomal protein S23, eukaryotic/archaeal + Ribosomal protein S12/S23 + Nucleic acid-binding, OB-fold Bcin04g05450 281 Bcin04g05460 73 SignalP-TM//Effector(V1) Protein of unknown function DUF1242 Bcin04g05470 146 Effector(V1) "Bctaf13, similar to yeast TAF13, TFIID subunit (19 kDa); involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors [Source:SGD;Acc:S000004564]" Bcin04g05480 345 Actin cortical patch SUR7/pH-response regulator PalI Bcin04g05490 480 SignalP-noTM PLC-like phosphodiesterase, TIM beta/alpha-barrel domain Bcin04g05500 362 Protease "Bcura4, similar to yeast URA4, Dihydroorotase; catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate [Source:SGD;Acc:S000004412]" Bcin04g05510 1130 SNF2-related + SANT/Myb domain + Helicase, C-terminal + Homeodomain-like + Helicase superfamily 1/2, ATP-binding domain + ISWI, HAND domain + SLIDE domain + SANT domain + P-loop containing nucleoside triphosphate hydrolase + ISWI family Bcin04g05520 278 Bcin04g05530 575 SignalP-TM Bcin04g05540 441 Zinc finger, CCCH-type Bcin04g05550 102 Bcin04g05560 154 Effector(V1) Protein of unknown function DUF3602 Bcin04g05570 154 Effector(V1) Bcin04g05580 322 SignalP-noTM Intradiol ring-cleavage dioxygenase, C-terminal + Intradiol ring-cleavage dioxygenase, core Bcin04g05590 817 Forkhead-associated (FHA) domain + SMAD/FHA domain Bcin04g05600 442 Interferon-related developmental regulator, N-terminal + Armadillo-like helical + Armadillo-type fold Bcin04g05610 1007 "Bcosh3, similar to yeast OSH3, Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability [Source:SGD;Acc:S000001115]" Bcin04g05620 1407 "Bcspt6, similar to yeast SPT6, Nucleosome remodeling protein; functions in various aspects of transcription, chromatin maintenance, and RNA processing; required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region; required for H3K36 trimethylation but not dimethylation by Set2p [Source:SGD;Acc:S000003348]" Bcin04g05630 520 yes Signaling pathway Bcste7, Ste7 mitogen activated protein kinase kinase Bcin04g05640 294 HAD hydrolase, subfamily IA + HAD-like domain Bcin04g05650 504 SignalP-noTM Cupin 1 + RmlC-like cupin domain + RmlC-like jelly roll fold + Bicupin, oxalate decarboxylase/oxidase Bcin04g05660 213 CAZy : GT1 //Effector(V2)|Effector(V1) "Bcalg13, similar to yeast ALG13, Catalytic component of UDP-GlcNAc transferase; required for the second step of dolichyl-linked oligosaccharide synthesis; anchored to the ER membrane via interaction with Alg14p; similar to bacterial and human glycosyltransferases; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003015]" Bcin04g05670 343 "Bcrsm24, similar to yeast RSM24, Mitochondrial ribosomal protein of the small subunit [Source:SGD;Acc:S000002582]" Bcin04g05680 539 SM cluster CAR bis "Bchfd1, similar to yeast HFD1, Hexadecenal dehydrogenase; involved in the conversion of sphingosine 1-phosphate breakdown product hexadecenal to hexadecenoic acid; located in the mitochondrial outer membrane and also in lipid particles; has similarity to ALDH3A2, a human fatty aldehyde dehydrogenase (FALDH) mutated in Sjogren-Larsson syndrome, a neurocutaneous disorder [Source:SGD;Acc:S000004716]" Bcin04g05690 659 Bcin04g05700 333 Effector(V2) Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Bcin04g05710 337 "Bcrrp4, similar to yeast RRP4, Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain RNA binding domains; has similarity to human hRrp4p (EXOSC2) [Source:SGD;Acc:S000001111]" Bcin04g05720 364 Bcin04g05730 96 Effector(V2)|Effector(V1) Domain of unknown function DUF4536 Bcin04g05740 557 "Bcapm2, similar to yeast APM2, Protein of unknown function; homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport [Source:SGD;Acc:S000001011]" Bcin04g05750 549 Bcin04g05760 744 Ubiquitin-related domain Bcin04g05770 1367 Bcin04g05780 285 MICOS complex subunit Mic12 Bcin04g05790 211 "Bcmrpl8, similar to yeast MRPL8, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000003599]" Bcin04g05800 723 "Bcutp25, similar to yeast UTP25, Nucleolar protein; required for 35S pre-RNA processing and 40S ribosomal subunit biogenesis [Source:SGD;Acc:S000001353]" Bcin04g05810 362 Protease JAB1/MPN/MOV34 metalloenzyme domain + Rpn11/EIF3F C-terminal domain + Eukaryotic translation initiation factor 3 subunit F Bcin04g05820 802 Single-stranded nucleic acid binding R3H + SUZ domain Bcin04g05830 294 Zinc finger, CCHC-type Bcin04g05840 208 mRNA splicing factor, Cwf18 Bcin04g05850 1287 Pentatricopeptide repeat Bcin04g05860 233 Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin04g05870 234 Effector(V1) Nicotinamide N-methyltransferase-like + S-adenosyl-L-methionine-dependent methyltransferase + Protein-lysine N-methyltransferase Bcin04g05880 1211 SignalP-noTM "Bcaxl2, similar to yeast AXL2, Integral plasma membrane protein; required for axial budding in haploid cells; localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate [Source:SGD;Acc:S000001402]" Bcin04g05890 280 Bcin04g05900 67 Uncharacterised protein family SERF Bcin04g05910 257 Effector(V1) "Bcguk1, similar to yeast GUK1, Guanylate kinase; converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins [Source:SGD;Acc:S000002862]" Bcin04g05920 343 yes BcSep4, septin Bcin04g05930 204 Effector(V1) Ribosomal protein L32p + Zinc-binding ribosomal protein Bcin04g05940 325 "Bcski8, similar to yeast SKI8, Ski complex component and WD-repeat protein; mediates 3'-5' RNA degradation by the cytoplasmic exosome; also required for meiotic double-strand break recombination; null mutants have superkiller phenotype [Source:SGD;Acc:S000003181]" Bcin04g05950 174 SignalP-noTM Bcin04g05960 301 SignalP-noTM Cupredoxin Bcin04g05970 159 Bcin04g05980 344 "Bclst8, similar to yeast LST8, Protein required for the transport of Gap1p; required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat [Source:SGD;Acc:S000004951]" Bcin04g05990 668 Bcin04g06000 171 SignalP-TM//SignalP& 0TM& >3cys& Len<300aa Bcin04g06010 1099 Bcin04g06020 987 CAZy : GH35PCW hemicellulose//SignalP-noTM//Early secretome Glycoside hydrolase, family 35 + Galactose-binding domain-like + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Beta-galactosidase, domain 2 + Beta-galactosidase jelly roll domain + Beta-galactosidase, domain 3 + Glycoside hydrolase 35, catalytic domain Bcin04g06030 271 Bcin04g06040 785 CAZy : GT2 Nucleotide-diphospho-sugar transferases Bcin04g06050 344 CAZy : GH12PCW cellulose//SignalP-noTM Glycoside hydrolase, family 11/12 + Concanavalin A-like lectin/glucanase domain Bcin04g06060 1112 WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin04g06070 615 Transporter "Bcssy1, similar to yeast SSY1, Component of the SPS plasma membrane amino acid sensor system; senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes; other members are Ssy1p, Ptr3p, and Ssy5p [Source:SGD;Acc:S000002567]" Bcin04g06080 541 Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin04g06090 119 Bcin04g06100 1006 Bcin04g06110 238 Bcin04g06120 295 Bcin04g06130 474 Bcin04g06140 337 Pyrroline-5-carboxylate reductase + 6-phosphogluconate dehydrogenase C-terminal domain-like + NAD(P)-binding domain + Pyrroline-5-carboxylate reductase, catalytic, N-terminal + Pyrroline-5-carboxylate reductase, dimerisation domain Bcin04g06150 407 CAZy : GH76FCW //SignalP-noTM Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase Bcin04g06160 276 Bcin04g06170 963 "Bcmlh3, similar to yeast MLH3, Protein involved in DNA mismatch repair and meiotic recombination; involved in crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability [Source:SGD;Acc:S000006085]" Bcin04g06180 453 Bcin04g06190 536 Protease Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin04g06200 561 Glycosyltransferase, DXD sugar-binding motif + Nucleotide-diphospho-sugar transferases Bcin04g06210 548 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin04g06220 433 Major facilitator superfamily + Major facilitator superfamily domain Bcin04g06230 433 Bcfhg1, Flavohemoglobin 1 Bcin04g06240 356 2-nitropropane dioxygenase, NPD + Aldolase-type TIM barrel Bcin04g06250 497 CAZy : GH13Energy //SignalP-noTM Glycosyl hydrolase, family 13, catalytic domain + Glycosyl hydrolase, family 13, all-beta + Glycoside hydrolase, catalytic domain + Alpha-amylase, domain of unknown function DUF1966, C-terminal + Glycoside hydrolase superfamily Bcin04g06260 313 Bcin04g06270 791 Bcin04g06280 501 Bcin04g06290 599 yes Signaling pathway Bcptc5, Type 2C Ser/Thr phosphatase (PP2C) Bcin04g06300 735 "Bcrqc1, similar to yeast RQC1, Component of the ribosome quality control complex (RQC); RQC (Rqc1p-Rkr1p-Tae2p-Cdc48p-Npl4p-Ufd1p) is a ribosome-bound complex required for the degradation of polypeptides arising from stalled translation; required along with Rkr1p for recruitment of the Cdc48p-Npl4p-Ufd1p AAA ATPase complex to the RQC [Source:SGD;Acc:S000002741]" Bcin04g06310 100 Effector(V2)|Effector(V1) "Bcatx1, similar to yeast ATX1, Cytosolic copper metallochaperone; transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p, which is a multicopper oxidase required for high-affinity iron uptake [Source:SGD;Acc:S000005203]" Bcin04g06320 381 Bcin04g06330 458 Thiolase-like + Thiolase, conserved site + Thiolase, acyl-enzyme intermediate active site + Thiolase, N-terminal + Thiolase, C-terminal Bcin04g06340 1102 Tetratricopeptide-like helical domain + Tetratricopeptide repeat + P-loop containing nucleoside triphosphate hydrolase Bcin04g06350 525 Alpha/Beta hydrolase fold Bcin04g06360 674 Bcin04g06370 640 Amino acid/polyamine transporter I Bcin04g06380 182 yes SignalP-noTM//Effector(V1) BcHsbA2, hydrophobic surface binding protein Bcin04g06390 544 Major facilitator superfamily + Major facilitator superfamily domain Bcin04g06400 705 "Bcgut2, similar to yeast GUT2, Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner [Source:SGD;Acc:S000001417]" Bcin04g06410 589 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin04g06420 292 Alpha/Beta hydrolase fold Bcin04g06430 1675 Bcin04g06440 473 Leucine-rich repeat domain, L domain-like Bcin04g06450 386 Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin04g06460 675 Bcin04g06470 372 Bcin04g06480 301 Bcin04g06490 205 Effector(V2)|Effector(V1) Bcin04g06500 287 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin04g06510 324 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin04g06520 154 Bcin04g06530 443 Bcin04g06540 265 Bcin04g06550 653 Heterokaryon incompatibility Bcin04g06560 1188 Ras-like guanine nucleotide exchange factor, N-terminal + SH3 domain + Ras guanine-nucleotide exchange factors catalytic domain + Ras guanine nucleotide exchange factor domain Bcin04g06570 767 "Bcmet6, similar to yeast MET6, Cobalamin-independent methionine synthase; involved in methionine biosynthesis and regeneration; requires a minimum of two glutamates on the methyltetrahydrofolate substrate, similar to bacterial metE homologs [Source:SGD;Acc:S000000893]" Bcin04g06580 65 Effector(V1) Bcin04g06590 256 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin04g06600 545 Transporter "Bcmup3, similar to yeast MUP3, Low affinity methionine permease; similar to Mup1p [Source:SGD;Acc:S000001028]" Bcin04g06610 306 Rotavirus A/C, non-structural protein 5 Bcin04g06620 265 SM 0 Protein of unknown function DUF3328 Bcin04g06630 94 SignalP-noTM Bcin04g06640 505 Bcin04g06650 536 SignalP-noTM Bcin04g06660 988 T-complex 11 Bcin04g06670 877 "Bcrim20, similar to yeast RIM20, Protein involved in proteolytic activation of Rim101p; part of response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation [Source:SGD;Acc:S000005801]" Bcin04g06680 532 CAZy : GT31 Fringe-like Bcin04g06690 448 "Bcpof1, similar to yeast POF1, Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT); catalyzes the conversion of nicotinamide mononucleotide (NMN) to nicotinamide adenine dinucleotide (NAD+); role in the nicotinamide riboside (NR) salvage pathway of NAD+ biosynthesis; involved in NR and NAD+ homeostasis; ATPase involved in protein quality control and filamentation pathways; interacts physically with Kss1p and suppresses the filamentation defect of a kss1 deletion [Source:SGD;Acc:S000000552]" Bcin04g06700 296 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal + 3-oxo-5-alpha-steroid 4-dehydrogenase Bcin04g06710 540 yes Bcaqp6, Aquaporin Bcin04g06720 1211 Protein kinase domain + Protein kinase-like domain + Protein kinase, ATP binding site + Calcium/calmodulin-dependent/calcium-dependent protein kinase Bcin04g06730 329 SignalP-noTM//Early secretome Extracellular membrane protein, CFEM domain Bcin04g06740 909 Ribonucleotide reductase large subunit, C-terminal + ATP-cone + Ribonucleotide reductase R1 subunit, N-terminal + Ribonucleotide reductase, class I , alpha subunit + Ribonucleotide reductase large subunit, N-terminal Bcin04g06750 325 Membrane insertase OXA1/ALB3/YidC Bcin04g06760 561 CAZy : GT4 //Early secretome "Bcalg11, similar to yeast ALG11, Alpha-1,2-mannosyltransferase; catalyzes sequential addition of the two terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER [Source:SGD;Acc:S000004993]" Bcin04g06770 582 Protease//SignalP-noTM Gamma-glutamyltranspeptidase + Nucleophile aminohydrolases, N-terminal Bcin04g06780 951 Protein of unknown function DUF3716 Bcin04g06790 263 Bzip transcription factor//Effector(V1) Basic-leucine zipper domain Bcin04g06800 1024 Dynamin superfamily + P-loop containing nucleoside triphosphate hydrolase Bcin04g06810 515 Centromere protein Chl4/mis15/CENP-N Bcin04g06820 372 TatD family + Deoxyribonuclease, TatD-related, conserved site + Metal-dependent hydrolase Bcin04g06830 1329 Bcin04g06840 593 Bcin04g06850 321 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin04g06860 569 SignalP-noTM FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin04g06870 386 Carbon-nitrogen hydrolase Bcin04g06880 866 Domain of unknown function DUF221 + Protein of unknown function DUF3779, phosphate metabolism + Domain of unknown function DUF4463 + Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain Bcin04g06890 207 Carbonic anhydrase Bcin04g06900 342 Effector(V2) Bcin04g06910 171 SignalP-noTM Bcin04g06920 553 Protease//SignalP-noTM Carboxylesterase, type B + Alpha/Beta hydrolase fold Bcin04g06930 214 Effector(V2) "Bclot6, similar to yeast LOT6, FMN-dependent NAD(P)H:quinone reductase; role in apoptosis-like cell death; may be involved in quinone detoxification; expression elevated at low temperature; sequesters the Cin5p transcription factor in the cytoplasm in complex with the proteasome under reducing conditions [Source:SGD;Acc:S000004001]" Bcin04g06970 250 Effector(V1) Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin04g06980 214 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin04g06990 321 SignalP-noTM//Effector(V2) Glycoside hydrolase, family 43 + Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase + Glycosyl hydrolase, five-bladed beta-propellor domain Bcin05g00004 112 Bcin05g00005 211 Effector(V2)|Effector(V1) Bcin05g00008 438 Bcin05g00010 344 NADP-dependent oxidoreductase domain Bcin05g00020 419 Zn(2)-C6 fungal-type DNA-binding domain Bcin05g00030 131 Bcin05g00040 363 SignalP-noTM Protein of unknown function DUF3500 Bcin05g00050 1178 Viral A-type inclusion protein repeat Bcin05g00060 553 Protease "Bcsad1, similar to yeast SAD1, Conserved zinc-finger domain protein involved in pre-mRNA splicing; critical for splicing of nearly all intron-containing genes; required for assembly of U4 snRNA into the U4/U6 particle [Source:SGD;Acc:S000001901]" Bcin05g00070 579 "Bcrrp9, similar to yeast RRP9, Protein involved in pre-rRNA processing; associated with U3 snRNP; component of small ribosomal subunit (SSU) processosome; ortholog of the human U3-55k protein [Source:SGD;Acc:S000006341]" Bcin05g00080 203 Protease//Effector(V2)|Effector(V1) "Bcpre1, similar to yeast PRE1, Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle [Source:SGD;Acc:S000000814]" Bcin05g00090 683 ATP-dependent RNA helicase DEAD-box, conserved site + Helicase, C-terminal + DEAD/DEAH box helicase domain + Helicase superfamily 1/2, ATP-binding domain + RNA helicase, DEAD-box type, Q motif + P-loop containing nucleoside triphosphate hydrolase Bcin05g00100 112 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin05g00110 429 Protease Peptidase M20 + Peptidase M20, dimerisation domain + Amidohydrolase Bcin05g00120 255 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin05g00130 237 LPS-induced tumour necrosis factor alpha factor Bcin05g00140 1084 CAZy : GH47 //SignalP-TM "Bcmnl1, similar to yeast MNL1, Alpha-1,2-specific exomannosidase of the endoplasmic reticulum; in complex with Pdi1p, generates a Man7GlcNac2 oligosaccharide signal on glycoproteins destined for ubiquitin-proteasome degradation [Source:SGD;Acc:S000001247]" Bcin05g00150 604 SignalP-noTM "Bcero1, similar to yeast ERO1, Thiol oxidase required for oxidative protein folding in the ER; essential for maintaining proper redox balance in ER; feedback regulation of Ero1p occurs via reduction and oxidation of Ero1p regulatory bonds; reduced Pdi1p activates Ero1p by direct reduction of Ero1p regulatory bonds; depletion of thiol substrates and accumulation of oxidized Pdi1p results in inactivation of Ero1p by both Pdi1p-mediated oxidation and autonomous oxidation of Ero1p regulatory bonds [Source:SGD;Acc:S000004599]" Bcin05g00160 116 "Bccks1, similar to yeast CKS1, Cyclin-dependent protein kinase regulatory subunit and adaptor; interacts with Cdc28p(Cdk1p); required for G1/S and G2/M phase transitions and budding; mediates the phosphorylation and degradation of Sic1p; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters [Source:SGD;Acc:S000000339]" Bcin05g00170 690 Bromodomain Bcin05g00180 614 Heat shock protein 70 family + Heat shock protein 70, conserved site + Heat shock protein 70kD, peptide-binding domain + Heat shock protein 70kD, C-terminal domain Bcin05g00190 284 Ribosome recycling factor + Ribosome recycling factor domain Bcin05g00200 380 Bcin05g00210 158 Anaphase-promoting complex, subunit CDC26 Bcin05g00220 1585 Protease "Bctaf2, similar to yeast TAF2, TFIID subunit (150 kDa); involved in RNA polymerase II transcription initiation [Source:SGD;Acc:S000000638]" Bcin05g00230 504 Something about silencing protein 4 Bcin05g00240 1181 yes Transporter Bcccc2, Copper-transporting ATPase Bcin05g00250 377 Protein of unknown function DUF3112 Bcin05g00260 594 "Bcrmd8, similar to yeast RMD8, Cytosolic protein required for sporulation [Source:SGD;Acc:S000001944]" Bcin05g00270 116 Effector(V2)|Effector(V1) Bcin05g00280 113 Effector(V2)|Effector(V1) Bcin05g00290 1002 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin05g00300 425 Peptidase M48 Bcin05g00310 715 SignalP-noTM Six-hairpin glycosidase-like + Domain of unknown function DUF1793 + Domain of unknown function DUF4965 + Domain of unknown function DUF5127 Bcin05g00320 367 Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin05g00330 438 "Bcdsk2, similar to yeast DSK2, Nuclear-enriched ubiquitin-like polyubiquitin-binding protein; required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle; involved in proteolysis; interacts with the proteasome; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004889]" Bcin05g00340 339 Effector(V2) Quinone oxidoreductase/zeta-crystallin, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin05g00350 553 yes Signaling pathway BcnoxA, NADPH oxidase Bcin05g00360 1242 SH3 domain + Myosin head, motor domain + Myosin tail 2 + P-loop containing nucleoside triphosphate hydrolase Bcin05g00370 350 Domain of unknown function DUF1713, mitochondria Bcin05g00380 303 Effector(V1) Bcin05g00390 586 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin05g00400 455 Zinc finger, DHHC-type transcription factor "Bcpfa4, similar to yeast PFA4, Palmitoyltransferase with autoacylation activity; required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases [Source:SGD;Acc:S000005363]" Bcin05g00410 308 SignalP-noTM Bcin05g00420 514 "Bcqri1, similar to yeast QRI1, UDP-N-acetylglucosamine pyrophosphorylase; catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002261]" Bcin05g00430 439 Uracil-DNA glycosylase-like + DNA glycosylase, G/T mismatch Bcin05g00440 353 "Bcyim1, similar to yeast YIM1, Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; may have a role in lipid metabolism, based on localization to lipid droplets; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004760]" Bcin05g00450 1044 "Bckap120, similar to yeast KAP120, Karyopherin responsible for the nuclear import of Rpf1p; Rpf1p is a ribosome maturation factor [Source:SGD;Acc:S000006046]" Bcin05g00460 651 Bcin05g00470 184 Bcin05g00480 217 Effector(V2)|Effector(V1) Phosphoribosyltransferase domain + Adenine phosphoribosyl transferase + Phosphoribosyltransferase-like Bcin05g00490 106 Effector(V1) Bcin05g00500 169 Bcin05g00510 274 HAD hydrolase, subfamily IA + HAD-like domain Bcin05g00520 82 Effector(V1) Bcin05g00530 408 Protease Beta-lactamase-related + Beta-lactamase/transpeptidase-like Bcin05g00540 2506 Signaling pathway Bchhk1, Histidine kinase - group X Bcin05g00550 109 Bcin05g00560 165 Effector(V2)|Effector(V1) S-adenosyl-L-methionine-dependent methyltransferase Bcin05g00570 398 Triose-phosphate transporter domain Bcin05g00580 513 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin05g00590 436 SignalP-noTM Bcprd4, Peroxidase Bcin05g00600 551 Fungal trans transcription factor Transcription factor domain, fungi Bcin05g00610 89 Effector(V2)|Effector(V1) Bcin05g00620 516 Bcin05g00630 831 Rab-GTPase-TBC domain Bcin05g00640 818 Ankyrin repeat + Dilute + Ankyrin repeat-containing domain Bcin05g00650 355 "Bcdal2, similar to yeast DAL2, Allantoicase; converts allantoate to urea and ureidoglycolate in the second step of allantoin degradation; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation [Source:SGD;Acc:S000001468]" Bcin05g00660 256 Effector(V1) Cytochrome b561/ferric reductase transmembrane Bcin05g00670 826 Protease Peptidase M13 + Peptidase M13, N-terminal domain + Peptidase M13, C-terminal domain + Metallopeptidase, catalytic domain Bcin05g00680 2129 Bchhk2, Histidine kinase - group V Bcin05g00690 1094 Bcin05g00700 843 Bcin05g00710 84 Effector(V1) "Bclsm5, similar to yeast LSM5, Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA [Source:SGD;Acc:S000000948]" Bcin05g00720 664 3'-5' exonuclease domain + Ribonuclease H-like domain Bcin05g00730 563 Bccat4, Catalase Bcin05g00740 535 Protease Carboxylesterase, type B + Alpha/Beta hydrolase fold Bcin05g00750 843 WD40 repeat + F-box domain + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin05g00760 1071 yes Effector(V2)//Signaling pathway Bccdc24, RhoGEF protein Bcin05g00770 97 Effector(V2)|Effector(V1) "Bcmrp10, similar to yeast MRP10, Mitochondrial ribosomal protein of the small subunit; contains twin cysteine-x9-cysteine motifs; oxidized by Mia40p during import into mitochondria [Source:SGD;Acc:S000006430]" Bcin05g00780 924 Bcin05g00790 926 G-patch domain + Tuftelin interacting protein, N-terminal domain + GC-rich sequence DNA-binding factor domain Bcin05g00800 737 BTB/POZ-like + BTB/POZ fold + Kelch-type beta propeller Bcin05g00810 597 "Bccdc20, similar to yeast CDC20, Activator of anaphase-promoting complex/cyclosome (APC/C); APC/C is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; cell-cycle regulated; potential Cdc28p substrate; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003084]" Bcin05g00820 455 "Bctoa1, similar to yeast TOA1, TFIIA large subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; required, along with Toa2p, for ribosomal protein gene transcription in vivo; homologous to largest and second largest subunits of human and Drosophila TFIIA [Source:SGD;Acc:S000005720]" Bcin05g00830 357 yes Bcmimp1, Mitochondrial protein transiently expressed in planta Bcin05g00840 3207 "Bcvps13, similar to yeast VPS13, Protein involved in prospore membrane morphogenesis; heterooligomeric or homooligomeric complex; peripherally associated with membranes; involved in sporulation, vacuolar protein sorting, prospore membrane formation during sporulatoin, and protein-Golgi retention; homologous to human CHAC and COH1 which are involved in chorea acanthocytosis and Cohen syndrome, respectively [Source:SGD;Acc:S000003963]" Bcin05g00850 542 Sds3-like Bcin05g00860 271 SignalP-noTM Alpha carbonic anhydrase + Carbonic anhydrase, alpha-class Bcin05g00870 1180 Ubiquitin-conjugating enzyme E2 + Poly(ADP-ribose) polymerase, catalytic domain + Ubiquitin-conjugating enzyme/RWD-like Bcin05g00880 374 Bcin05g00890 651 Bcin05g00900 644 Bcin05g00910 351 Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin05g00920 212 SignalP-TM//Effector(V2)|Effector(V1) Bcin05g00930 1444 "Bcpan1, similar to yeast PAN1, Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p; associates with actin patches on cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates Arp2/3 complex in vitro; phosphorylation of Thr-1225 is regulated by MAPK Hog1p in response to osmotic stress; previously thought to be a subunit of poly(A) ribonuclease [Source:SGD;Acc:S000001445]" Bcin05g00940 527 S-adenosyl-L-methionine-dependent methyltransferase Bcin05g00950 199 Effector(V2) Bcin05g00960 483 "Bcmak11, similar to yeast MAK11, Protein involved in an early step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats [Source:SGD;Acc:S000001504]" Bcin05g00970 368 Insulin-induced protein family Bcin05g00980 1539 "Bceaf1, similar to yeast EAF1, Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 subunits into the native complex; required for initiation of pre-meiotic DNA replication, likely due to its requirement for expression of IME1 [Source:SGD;Acc:S000002767]" Bcin05g00990 369 Spp2/MOS2, G-patch domain Bcin05g01000 529 Cytochrome P450 + Cytochrome P450, E-class, group II + Cytochrome P450, E-class, CYP52 + Cytochrome P450, conserved site Bcin05g01010 252 "Bccoq10, similar to yeast COQ10, Coenzyme Q (ubiquinone) binding protein; functions in the delivery of Q6 to its proper location for electron transport during respiration; START domain protein with homologs in bacteria and eukaryotes [Source:SGD;Acc:S000005368]" Bcin05g01020 147 Bcin05g01030 358 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin05g01040 879 CAZy : GH2PCW/FCW Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich + Galactose-binding domain-like + Glycoside hydrolase, catalytic domain + Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain + Glycoside hydrolase superfamily Bcin05g01050 318 Bcin05g01060 597 Transporter Amino acid transporter, transmembrane domain Bcin05g01070 114 Bcin05g01080 199 "Bcarc15, similar to yeast ARC15, Subunit of the ARP2/3 complex; ARP2/3 is required for the motility and integrity of cortical actin patches; has mRNA binding activity [Source:SGD;Acc:S000001324]" Bcin05g01100 648 Bcin05g01110 313 "Bcpis1, similar to yeast PIS1, Phosphatidylinositol synthase; required for biosynthesis of phosphatidylinositol, which is a precursor for polyphosphoinositides, sphingolipids, and glycolipid anchors for some of the plasma membrane proteins [Source:SGD;Acc:S000006317]" Bcin05g01120 272 Protease//Effector(V1) Dienelactone hydrolase + Alpha/Beta hydrolase fold Bcin05g01130 1146 Bcin05g01140 210 "Bcatp20, similar to yeast ATP20, Subunit g of the mitochondrial F1F0 ATP synthase; reversibly phosphorylated on two residues; unphosphorylated form is required for dimerization of the ATP synthase complex, which in turn determines oligomerization of the complex and the shape of inner membrane cristae [Source:SGD;Acc:S000006224]" Bcin05g01150 374 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain Bcin05g01160 359 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + NAD(P)-binding domain Bcin05g01170 429 Bcin05g01180 98 Effector(V2) Bcin05g01190 239 Effector(V2)|Effector(V1) Bcin05g01200 579 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin05g01210 327 yes Signaling pathway Bclae1, Regulator of secondary metabolism laeA, component of the Velvet protein complex, protein implicated in photoreponses Bcin05g01220 566 Bcin05g01230 273 Bcin05g01240 374 Protease Band 7 protein + Stomatin family Bcin05g01250 415 Bcin05g01260 773 Bcin05g01270 106 Effector(V2)|Effector(V1) Methyltransferase type 11 + S-adenosyl-L-methionine-dependent methyltransferase Bcin05g01280 410 Heterokaryon incompatibility Bcin05g01290 106 Bcin05g01300 484 Ankyrin repeat + Ankyrin repeat-containing domain Bcin05g01310 231 SignalP-noTM//Effector(V1) Bcin05g01320 222 Effector(V1) Prion-inhibition and propagation, HeLo domain Bcin05g01330 338 Concanavalin A-like lectin/glucanase domain Bcin05g01340 706 Bcin05g01350 640 "Bctfb1, similar to yeast TFB1, Subunit of TFIIH and nucleotide excision repair factor 3 complexes; required for nucleotide excision repair, target for transcriptional activators; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002719]" Bcin05g01360 1048 "Bckgd1, similar to yeast KGD1, Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex; catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA [Source:SGD;Acc:S000001387]" Bcin05g01370 916 Bcin05g01380 346 Effector(V2) Oxidoreductase FAD/NAD(P)-binding + Flavoprotein pyridine nucleotide cytochrome reductase + NADH:cytochrome b5 reductase (CBR) + Oxidoreductase, FAD-binding domain + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel Bcin05g01390 670 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin05g01400 596 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin05g01410 261 Bcin05g01420 1742 "Bcrpo21, similar to yeast RPO21, RNA polymerase II largest subunit B220; part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime [Source:SGD;Acc:S000002299]" Bcin05g01430 557 yes Bcglr2, Glutathione reductase 2 Bcin05g01440 465 "Bcswd1, similar to yeast SWD1, Subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7 [Source:SGD;Acc:S000000064]" Bcin05g01450 433 SignalP-noTM Bcprd2, Peroxidase Bcin05g01460 321 SignalP-noTM//Effector(V2)|Effector(V1) Bcin05g01470 241 SET domain Bcin05g01480 164 Cytochrome c oxidase biogenesis protein Cmc1-like Bcin05g01490 257 "Bcutp11, similar to yeast UTP11, Subunit of U3-containing Small Subunit (SSU) processome complex; involved in production of 18S rRNA and assembly of small ribosomal subunit [Source:SGD;Acc:S000001582]" Bcin05g01500 535 Bcin05g01510 351 SignalP-noTM Bcin05g01520 453 CAZy : GH16FCW Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin05g01530 864 CAZy : GTnc Glycosyltransferase 2-like + Nucleotide-diphospho-sugar transferases Bcin05g01540 226 Effector(V2)|Effector(V1) SRA-YDG + PUA-like domain Bcin05g01550 322 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin05g01560 381 "Bcsds22, similar to yeast SDS22, Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p; whether it functions as a positive or negative regulator of Glc7p is controversial; involved in the regulation of Glc7p nuclear localization and function [Source:SGD;Acc:S000001676]" Bcin05g01570 373 Protease Alpha/Beta hydrolase fold Bcin05g01580 271 BTB/POZ-like + BTB/POZ fold Bcin05g01590 454 Proteasome component (PCI) domain Bcin05g01600 174 60S ribosomal protein L18a/ L20, eukaryotes + Ribosomal protein L18a/LX + 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Bcin05g01610 857 "Bcpxa1, similar to yeast PXA1, Subunit of a heterodimeric peroxisomal ABC transport complex; required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter ABCD1 and ABCD2 and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; complex also includes Pxa2p [Source:SGD;Acc:S000006068]" Bcin05g01620 580 NLI interacting factor + Dullard phosphatase domain, eukaryotic + HAD-like domain Bcin05g01630 110 Protein transport protein SecG/Sec61-beta/Sbh + Protein transport Sec61-beta/Sbh Bcin05g01640 1339 CAZy : GT1 UDP-glucuronosyl/UDP-glucosyltransferase + Ubiquitin interacting motif + Glycosyltransferase family 28, N-terminal domain Bcin05g01650 1344 Bcin05g01660 415 CAZy : GH5PCW/FCW Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin05g01670 367 Isopenicillin N synthase-like Bcin05g01680 273 Actin cross-linking + FRG1-like Bcin05g01690 334 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin05g01700 843 SignalP-noTM "Bchrd3, similar to yeast HRD3, ER membrane protein that plays a central role in ERAD; forms HRD complex with Hrd1p and ER-associated protein degradation (ERAD) determinants that engages in lumen to cytosol communication and coordination of ERAD events [Source:SGD;Acc:S000004197]" Bcin05g01710 128 Helix-loop-helix (HLH) transcription factor//Effector(V1) Myc-type, basic helix-loop-helix (bHLH) domain Bcin05g01720 826 NB-ARC + Domain of unknown function DUF676, lipase-like + P-loop containing nucleoside triphosphate hydrolase + Alpha/Beta hydrolase fold Bcin05g01730 1020 Cys2His2 transcription factor Bcin05g01740 286 Maf-like protein + Inosine triphosphate pyrophosphatase-like Bcin05g01750 918 SignalP-noTM Heterokaryon incompatibility Het-C Bcin05g01760 341 HMG (high mobility group) transcription factor High mobility group box domain Bcin05g01770 684 CAZy : GH71FCW //SignalP-noTM Glycoside hydrolase, family 71 Bcin05g01780 1040 Bcin05g01790 764 yes Zn2/Cys6 + fungal trans transcription factor//Signaling pathway Bcmrr1, Zn2/Cys6 transcription factor Bcin05g01800 174 Protease//Effector(V2)|Effector(V1) Phosphatidylethanolamine-binding protein PEBP Bcin05g01810 835 Protease Urease, beta subunit + Urease, gamma/gamma-beta subunit + Urease, alpha subunit + Amidohydrolase 1 + Urease + Metal-dependent hydrolase, composite domain + Urease alpha-subunit, N-terminal domain + Urease active site + Urease, alpha subunit, C-terminal + Urease nickel binding site + Metal-dependent hydrolase Bcin05g01820 564 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin05g01830 676 "Bcngg1, similar to yeast NGG1, Subunit of chromatin modifying histone acetyltransferase complexes; member of the ADA complex, the SAGA complex, and the SLIK complex; transcriptional regulator involved in glucose repression of Gal4p-regulated genes [Source:SGD;Acc:S000002583]" Bcin05g01840 732 Bcin05g01850 1010 Beta-lactamase-like + DNA repair metallo-beta-lactamase Bcin05g01860 357 Bcin05g01870 424 GNAT domain + Bromodomain + Acyl-CoA N-acyltransferase + Bromodomain, conserved site Bcin05g01880 79 Bcin05g01890 344 Rad1/Rec1/Rad17 Bcin05g01900 267 Bcin05g01910 281 Bcin05g01920 542 "Bcmst1, similar to yeast MST1, Mitochondrial threonyl-tRNA synthetase; aminoacylates both the canonical threonine tRNA tT(UGU)Q1 and the unusual threonine tRNA tT(UAG)Q2 in vitro [Source:SGD;Acc:S000001677]" Bcin05g01930 534 Bcin05g01940 542 Bcin05g01950 585 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin05g01960 544 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin05g01970 249 SignalP-noTM Bcin05g01980 511 Acyltransferase 3 Bcin05g01990 235 Bcin05g02000 279 Bcin05g02010 233 Effector(V2) GNAT domain + Acyl-CoA N-acyltransferase Bcin05g02020 269 Bcin05g02030 540 Transporter Major facilitator superfamily domain Bcin05g02040 256 Bcin05g02050 376 Bcalo1, AMID-like oxidoreductase 1 Bcin05g02060 316 Bcin05g02070 157 Effector(V2)|Effector(V1) Bcin05g02080 404 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin05g02090 304 RTA-like protein Bcin05g02100 321 Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin05g02110 685 Protein of unknown function DUF2985 Bcin05g02120 853 Leucine-rich repeat domain, L domain-like Bcin05g02130 598 Actin family + Actin-related protein 10 Bcin05g02140 939 XPG/Rad2 endonuclease + XPG N-terminal + XPG-I domain + 5'-3' exonuclease, C-terminal domain + PIN domain-like Bcin05g02150 473 Bcin05g02160 463 WD40 repeat + LIS1 homology motif + WD40/YVTN repeat-like-containing domain + Dynein regulator LIS1 + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin05g02170 882 "Bcstu2, similar to yeast STU2, Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p [Source:SGD;Acc:S000004035]" Bcin05g02180 74 Effector(V2)|Effector(V1) Bcin05g02190 679 "Bcscp1, similar to yeast SCP1, Component of yeast cortical actin cytoskeleton; binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin [Source:SGD;Acc:S000005894]" Bcin05g02200 330 Bcin05g02210 506 Bcin05g02220 133 Effector(V1) Bcin05g02230 462 Bcin05g02240 211 Effector(V1) "Bcyet3, similar to yeast YET3, Protein of unknown function; YET3 null mutant decreases the level of secreted invertase; homolog of human BAP31 protein; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002230]" Bcin05g02250 750 "Bcdus3, similar to yeast DUS3, Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000004393]" Bcin05g02260 519 Kelch repeat type 1 + Galactose oxidase/kelch, beta-propeller + Kelch repeat type 2 + Kelch-type beta propeller Bcin05g02270 114 Effector(V1) Bcin05g02280 683 Bcin05g02290 435 "Bcefm2, similar to yeast EFM2, S-adenosylmethionine-dependent methyltransferase; seven-beta-strand lysine methyltransferase which dimethylates translation elongation factor EF2 (Eft1p and Eft2p) at lysine 613 and methylates EF3 (Yef3p) at lysine 187; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; involved in regulation of translational termination; predicted involvement in ribosome biogenesis [Source:SGD;Acc:S000000475]" Bcin05g02300 410 "Bcnpr2, similar to yeast NPR2, Subunit of SEA (Seh1-associated), Npr2/3, and Iml1p complexes; Npr2/3 complex mediates downregulation of TORC1 activity upon amino acid limitation; SEA complex is a coatomer-related complex that associates dynamically with the vacuole; Iml1p complex is required for non-nitrogen-starvation (NNS)-induced autophagy; Iml1p interacts primarily with phosphorylated Npr2p; homolog of human tumor suppressor NPRL2; target of Grr1p; required for growth on urea and proline [Source:SGD;Acc:S000000788]" Bcin05g02310 756 Bcin05g02320 76 Effector(V2)|Effector(V1) "Bcrpb10, similar to yeast RPB10, RNA polymerase subunit ABC10-beta; common to RNA polymerases I, II, and III [Source:SGD;Acc:S000005736]" Bcin05g02330 1010 "Bcnan1, similar to yeast NAN1, U3 snoRNP protein; component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA; required for the biogenesis of18S rRNA [Source:SGD;Acc:S000006047]" Bcin05g02340 382 Oxoglutarate/iron-dependent dioxygenase + Non-haem dioxygenase N-terminal domain + Isopenicillin N synthase-like Bcin05g02350 86 Effector(V2)|Effector(V1) Uncharacterised protein family SERF + At2g23090 like Bcin05g02360 414 AT hook, DNA-binding motif Bcin05g02370 224 Effector(V2)|Effector(V1) Zinc finger, C6HC-type + E3 ubiquitin ligase RBR family Bcin05g02380 82 Effector(V1) Bcin05g02390 680 Cys2His2 transcription factor "Bcsfp1, similar to yeast SFP1, Regulates transcription of ribosomal protein and biogenesis genes; regulates response to nutrients and stress, G2/M transitions during mitotic cell cycle and DNA-damage response, and modulates cell size; regulated by TORC1 and Mrs6p; sequence of zinc finger, ChIP localization data, and protein-binding microarray (PBM) data, and computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p at others; can form the [ISP+] prion [Source:SGD;Acc:S000004395]" Bcin05g02400 299 "Bcrcf2, similar to yeast RCF2, Cytochrome c oxidase subunit; has a role in assembly of respiratory supercomplexes; similar to Rcf1p, and either Rcf1p or Rcf2p is required for late-stage assembly of the Cox12p and Cox13p subunits and for cytochrome c oxidase activity; associates with the cytochrome c oxidase - cytochrome bc1 supercomplex; null mutant accumulates reactive oxygen species; member of the conserved hypoxia induced gene family; C. elegans homolog is functional in yeast [Source:SGD;Acc:S000005301]" Bcin05g02410 676 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin05g02420 431 SignalP-noTM Extracellular membrane protein, CFEM domain Bcin05g02430 442 SignalP-noTM Bcprd8, Peroxidase Bcin05g02440 122 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin05g02450 246 Acyl-CoA N-acyltransferase Bcin05g02460 340 Bax inhibitor 1-related Bcin05g02470 959 Signaling pathway Cyclic nucleotide-binding domain + F-box domain + Leucine-rich repeat, cysteine-containing subtype + RmlC-like jelly roll fold + Cyclic nucleotide-binding, conserved site + Cyclic nucleotide-binding-like + Leucine-rich repeat domain, L domain-like Bcin05g02480 138 Effector(V2)|Effector(V1) Bcin05g02490 205 Effector(V2)|Effector(V1) "Bcmxr1, similar to yeast MXR1, Methionine-S-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan; reduced activity of human homolog implicated in Alzheimer disease [Source:SGD;Acc:S000000844]" Bcin05g02500 556 Cactin, central domain + Cactin, C-terminal Bcin05g02510 458 Fork head transcription factor Transcription factor, fork head + Winged helix-turn-helix DNA-binding domain Bcin05g02520 456 CAZy : GH28PCW pectin//SignalP-noTM//Early secretome Bcpgx1, Exo-polygalacturonase Bcin05g02530 586 Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin05g02540 427 S-adenosyl-L-methionine-dependent methyltransferase Bcin05g02550 250 CAZy : GHnc //SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Lysozyme-like domain Bcin05g02560 491 Bcin05g02570 444 Zinc/iron permease Bcin05g02580 139 Effector(V2)|Effector(V1) Ribosomal protein L14b/L23e + Ribosomal protein L14 conserved site Bcin05g02590 633 "Bcrpd3, similar to yeast RPD3, Histone deacetylase, component of both the Rpd3S and Rpd3L complexes; regulates transcription, silencing, autophagy and other processes by influencing chromatin remodeling; forms at least two different complexes which have distinct functions and members; Rpd3(L) recruitment to the subtelomeric region is regulated by interaction with the arginine methyltransferase, Hmt1p [Source:SGD;Acc:S000005274]" Bcin05g02600 334 Protease JAB1/MPN/MOV34 metalloenzyme domain + Rpn11/EIF3F C-terminal domain Bcin05g02610 66 Bcin05g02620 298 Effector(V1) Pyruvate/Phosphoenolpyruvate kinase-like domain + Isocitrate lyase/phosphorylmutase, conserved site Bcin05g02630 391 Protease "Bcwss1, similar to yeast WSS1, Metalloprotease involved in DNA repair, removes DNA-protein crosslinks at stalled replication forks during replication of damaged DNA; sumoylated protein localizing to the nuclear periphery of mother cells; localizes to a single spot on the nuclear periphery of mother cells but not daughters; interacts genetically with SMT3; activated by DNA binding [Source:SGD;Acc:S000001176]" Bcin05g02640 491 Protein of unknown function DUF1776, fungi + NAD(P)-binding domain Bcin05g02650 260 Effector(V2)|Effector(V1) "Bcyth1, similar to yeast YTH1, Essential RNA-binding component of cleavage and polyadenylation factor; contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006311]" Bcin05g02660 377 CAZy : GH18FCW BcchiB, Fungal family 18 chitinases, group A, clades A-IV, subclade CHI18-3 (Choquer et al., mycological research 111 (2007) 615-625) Bcin05g02670 832 "Bcvps53, similar to yeast VPS53, Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; required for vacuolar protein sorting; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p, [Source:SGD;Acc:S000003566]" Bcin05g02680 346 yes Bctrr1, Thioredoxin reductase Bcin05g02690 157 SignalP-noTM//Effector(V2)|Effector(V1) Bcin05g02700 585 Protein of unknown function DUF3431 Bcin05g02710 510 Cytochrome P450 + Cytochrome P450, E-class, CYP52 + Cytochrome P450, conserved site Bcin05g02720 635 Membrane bound O-acyl transferase, MBOAT Bcin05g02730 175 Effector(V2)|Effector(V1) Metallopeptidase, catalytic domain Bcin05g02740 263 Bcin05g02750 232 Bcin05g02760 483 Cation/H+ exchanger Bcin05g02770 512 Homeodomain-like Bcin05g02780 750 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin05g02790 272 Smr protein/MutS2 C-terminal + Domain of unknown function DUF1771 Bcin05g02800 389 Bcin05g02810 592 Transporter Amino acid permease, fungi + Amino acid permease, conserved site + Amino acid permease/ SLC12A domain Bcin05g02820 636 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin05g02830 568 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin05g02840 1134 yes Signaling pathway Bcplc1, Phosphoinositide-specific phospholipase C Bcin05g02850 309 Bcin05g02860 1489 Bcin05g02870 423 "Bcrpn6, similar to yeast RPN6, Essential, non-ATPase regulatory subunit of the 26S proteasome lid; required for the assembly and activity of the 26S proteasome; the human homolog (S9 protein) partially rescues Rpn6p depletion; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002255]" Bcin05g02880 442 "Bcsof1, similar to yeast SOF1, Protein required for biogenesis of 40S (small) ribosomal subunit; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p; essential gene [Source:SGD;Acc:S000003934]" Bcin05g02890 131 Effector(V2)|Effector(V1) Bcin05g02900 416 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin05g02910 538 "Bccct3, similar to yeast CCT3, Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo; capable of binding Q/N rich proteins and mediating their folding [Source:SGD;Acc:S000003551]" Bcin05g02920 197 Protein of unknown function DUF1168 Bcin05g02930 488 "Bcdet1, similar to yeast DET1, Acid phosphatase; involved in the non-vesicular transport of sterols in both directions between the endoplasmic reticulum and plasma membrane; deletion confers sensitivity to nickel [Source:SGD;Acc:S000002458]" Bcin05g02940 686 Protein kinase domain + Protein kinase-like domain Bcin05g02950 160 Effector(V2)|Effector(V1) Bcin05g02960 841 Zn2/Cys6 + fungal trans transcription factor//Signaling pathway Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin05g02970 185 Effector(V1) Bcin05g02980 339 Bcin05g02990 118 Effector(V1) Bcin05g03000 961 "Bcala1, similar to yeast ALA1, Cytoplasmic and mitochondrial alanyl-tRNA synthetase; required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog [Source:SGD;Acc:S000005862]" Bcin05g03010 229 Bcin05g03020 190 Effector(V2)|Effector(V1) Chitin synthesis regulation, Congo red resistance, RCR protein Bcin05g03030 1606 "Bcvps8, similar to yeast VPS8, Membrane-binding component of the CORVET complex; involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway; interacts with Vps21p; contains RING finger motif [Source:SGD;Acc:S000000002]" Bcin05g03040 372 Protein of unknown function DUF3752 Bcin05g03050 522 Permease, cytosine/purines, uracil, thiamine, allantoin + Purine-cytosine permease Bcin05g03060 343 Beta-lactamase-like Bcin05g03070 446 SignalP-noTM Bcin05g03080 180 yes Effector(V2)|Effector(V1) BcCyp2, Cyclophilin 2 Bcin05g03090 463 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin05g03100 587 "Bcsti1, similar to yeast STI1, Hsp90 cochaperone; interacts with the Ssa group of the cytosolic Hsp70 chaperones and activates Ssa1p ATPase activity; interacts with Hsp90 chaperones and inhibits their ATPase activity; homolog of mammalian Hop [Source:SGD;Acc:S000005553]" Bcin05g03110 1083 "Bcspa2, similar to yeast SPA2, Component of the polarisome; functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate; coding sequence contains length polymorphisms in different strains; SPA2 has a paralog, SPH1, that arose from the whole genome duplication [Source:SGD;Acc:S000003944]" Bcin05g03120 260 "Bcssu72, similar to yeast SSU72, Phosphatase and transcription/RNA-processing factor; associates with TFIIB and cleavage/polyadenylation factor Pta1p; exhibits phosphatase activity on serine-5 and serine-7 of the RNA polymerase II C-terminal domain; affects start site selection and transcriptional read through in vivo [Source:SGD;Acc:S000005166]" Bcin05g03130 560 "Bcnbp2, similar to yeast NBP2, Protein involved in the HOG (high osmolarity glycerol) pathway; negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex; interacts with Bck1p and down regulates the cell wall integrity pathway; found in the nucleus and cytoplasm, contains an SH3 domain and a Ptc1p binding domain (PBM) [Source:SGD;Acc:S000002569]" Bcin05g03140 231 Effector(V2)|Effector(V1) "Bcpnc1, similar to yeast PNC1, Nicotinamidase that converts nicotinamide to nicotinic acid; part of the NAD(+) salvage pathway; required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span; protein increases in abundance and relative distribution to cytoplasmic foci decreases upon DNA replication stress [Source:SGD;Acc:S000003005]" Bcin05g03150 1213 Sterol-sensing domain + Hydroxymethylglutaryl-CoA reductase, class I/II + Hydroxymethylglutaryl-CoA reductase, eukaryotic/arcaheal type + Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain + Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain + Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain + Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site + Hydroxymethylglutaryl-CoA reductase, N-terminal + HMG-CoA reductase, N-terminal domain Bcin05g03160 591 UV radiation resistance protein/autophagy-related protein 14 Bcin05g03170 547 Transporter Amino acid/polyamine transporter I Bcin05g03180 240 Effector(V2) S-adenosyl-L-methionine-dependent methyltransferase Bcin05g03190 410 SignalP-noTM Bcin05g03200 523 Protein kinase domain + Protein kinase-like domain Bcin05g03210 283 Cell fusion protein Dni1/Fig1 Bcin05g03220 297 Bcin05g03230 821 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site + Probable phosphoketolase + Thiamin diphosphate-binding fold Bcin05g03240 558 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin05g03250 267 Adenylate kinase/UMP-CMP kinase + Adenylate kinase, active site lid domain + P-loop containing nucleoside triphosphate hydrolase + Adenylate kinase 3/4, mitochondrial + Adenylate kinase, conserved site Bcin05g03260 122 Bcin05g03270 548 LETM1-like + Letm1 ribosome-binding domain Bcin05g03280 463 Phox homologous domain + Arfaptin homology (AH) domain/BAR domain Bcin05g03290 858 Protease//SignalP-noTM "Bckex2, similar to yeast KEX2, Kexin, a subtilisin-like protease (proprotein convertase); a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway [Source:SGD;Acc:S000005182]" Bcin05g03300 1620 Metallo-dependent phosphatase-like Bcin05g03310 596 DNA double-strand break repair and VJ recombination XRCC4, N-terminal + XLF/Cernunnos Bcin05g03320 442 Bcin05g03330 218 Bcin05g03340 1164 "Bcrtc1, similar to yeast RTC1, Subunit of the SEA (Seh1-associated) complex; SEA is a coatomer-related complex that associates dynamically with the vacuole; null mutation suppresses cdc13-1 temperature sensitivity; has N-terminal WD-40 repeats and a C-terminal RING motif [Source:SGD;Acc:S000005498]" Bcin05g03350 291 Bcin05g03360 338 CAZy : GT8 Glycosyl transferase, family 8 + Nucleotide-diphospho-sugar transferases Bcin05g03370 424 CAZy : GT69 Mannosyltransferase 1, CMT1 Bcin05g03380 499 Aldehyde dehydrogenase domain + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain + Aldehyde dehydrogenase, C-terminal Bcin05g03390 421 CAZy : GH5PCW/FCW //SignalP-noTM Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin05g03400 83 Effector(V1) Bcin05g03410 349 RmlC-like cupin domain + Cupin 2, conserved barrel + RmlC-like jelly roll fold Bcin05g03420 323 Steryl acetyl hydrolase + Alpha/Beta hydrolase fold Bcin05g03430 327 "Bckti12, similar to yeast KTI12, Protein that plays a role in modification of tRNA wobble nucleosides; protein plays role in tRNA wobble nucleoside modification with Elongator complex; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p [Source:SGD;Acc:S000001593]" Bcin05g03440 605 Cys2His2 transcription factor Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin05g03450 594 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin05g03460 378 SignalP-noTM Putative lysophospholipase + Alpha/Beta hydrolase fold Bcin05g03470 234 Effector(V2)|Effector(V1) Bcin05g03480 275 Frag1/DRAM/Sfk1 Bcin05g03490 400 "Bckin28, similar to yeast KIN28, Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]" Bcin05g03500 939 "Bcrcy1, similar to yeast RCY1, F-box protein involved in recycling endocytosed proteins; involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth; direct interaction with C-terminal cytoplasmic region of Drs2p plays an important role for Drs2p function in endocytic recycling pathway [Source:SGD;Acc:S000003740]" Bcin05g03510 441 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin05g03520 324 UbiA prenyltransferase family Bcin05g03530 350 Bcin05g03540 399 Early secretome O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin05g03550 587 Bclcc4, Laccase Bcin05g03560 883 Eisosome protein 1 Bcin05g03570 296 Effector(V2)|Effector(V1) Tyrosine/serine-protein phosphatase IphP-type + Protein-tyrosine phosphatase-like Bcin05g03580 357 Protease//SignalP-noTM Peptidase G1 + Concanavalin A-like lectin/glucanase domain Bcin05g03590 410 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin05g03600 389 Taurine catabolism dioxygenase TauD/TfdA Bcin05g03610 1516 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin05g03620 230 Dimeric alpha-beta barrel Bcin05g03630 232 GNAT domain + Acyl-CoA N-acyltransferase Bcin05g03640 991 "Bcapl3, similar to yeast APL3, Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport [Source:SGD;Acc:S000000133]" Bcin05g03650 352 S-adenosyl-L-methionine-dependent methyltransferase Bcin05g03660 160 Major facilitator superfamily domain Bcin05g03670 450 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin05g03680 90 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) BcSSP2, Small secreted protein Bcin05g03690 979 Bcin05g03700 1129 Bcin05g03710 717 "Bcies1, similar to yeast IES1, Subunit of the INO80 chromatin remodeling complex; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000001881]" Bcin05g03720 167 Bzip transcription factor Basic-leucine zipper domain Bcin05g03730 235 Sterile alpha motif/pointed domain + IGR protein motif Bcin05g03740 1505 "Bcirc20, similar to yeast IRC20, E3 ubiquitin ligase and putative helicase; involved in synthesis-dependent strand annealing-mediated homologous recombination; ensures precise end-joining along with Srs2p in the Yku70p/Yku80p/Lig4p-dependent nonhomologous end joining (NHEJ) pathway; localizes to both the mitochondrion and the nucleus; contains a Snf2/Swi2 family ATPase/helicase and a RING finger domain; interacts with Cdc48p and Smt3p; null mutant displays increased levels of spontaneous Rad52p foci [Source:SGD;Acc:S000004237]" Bcin05g03750 348 "Bccha1, similar to yeast CHA1, Catabolic L-serine (L-threonine) deaminase; catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine [Source:SGD;Acc:S000000569]" Bcin05g03760 331 Protein prenyltransferase, alpha subunit Bcin05g03770 498 "Bcerg12, similar to yeast ERG12, Mevalonate kinase; acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate [Source:SGD;Acc:S000004821]" Bcin05g03780 431 Bcin05g03790 784 Protease "Bcyme1, similar to yeast YME1, Catalytic subunit of the i-AAA protease complex; complex is located in the mitochondrial inner membrane; responsible for degradation of unfolded or misfolded mitochondrial gene products; serves as a nonconventional translocation motor to pull PNPase into the intermembrane space; also has a role in intermembrane space protein folding; mutation causes an elevated rate of mitochondrial turnover [Source:SGD;Acc:S000006228]" Bcin05g03800 411 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin05g03810 422 Bcin05g03820 232 Effector(V2)|Effector(V1) Nitroreductase-like + Nitroreductase Bcin05g03830 456 Protease Bcmep, Secreted protease Bcin05g03840 190 Bcin05g03850 126 Ribosomal protein L34 Bcin05g03860 124 Effector(V1) Bcin05g03870 99 SignalP-noTM Bcin05g03880 502 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin05g03890 353 "Bcrer2, similar to yeast RER2, Cis-prenyltransferase involved in dolichol synthesis; major enzyme of polyprenol synthesis in both the endoplasmic reticulum (ER) and in lipid droplets; participates in ER protein sorting [Source:SGD;Acc:S000000206]" Bcin05g03900 707 "Bcpho23, similar to yeast PHO23, Component of the Rpd3L histone deacetylase complex; involved in transcriptional regulation of PHO5; affects termination of snoRNAs and cryptic unstable transcripts (CUTs); C-terminus has similarity to human candidate tumor suppressor p33(ING1) and its isoform ING3 [Source:SGD;Acc:S000005041]" Bcin05g03910 132 Effector(V1) Bcin05g03920 655 Leucine-rich repeat domain, L domain-like Bcin05g03930 1030 Up-regulated during septation protein 1 Bcin05g03940 497 "Bcpol31, similar to yeast POL31, Subunit of DNA polymerase delta (polymerase III); essential for cell viability; involved in DNA replication and DNA repair; forms a complex with Rev3p, Rev7p and Pol32p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003766]" Bcin05g03950 1336 "Bcvhc1, similar to yeast VHC1, Vacuolar membrane cation-chloride cotransporter (CCC); likely mediates K+ and Cl- cotransport into the vacuole; has a role in potassium homeostasis and salt tolerance; similar to mammalian electroneutral Na(+)-(K+)-C1- cotransporter family [Source:SGD;Acc:S000000439]" Bcin05g03960 792 Transporter Amino acid transporter, transmembrane domain Bcin05g03970 356 2-nitropropane dioxygenase, NPD + Aldolase-type TIM barrel Bcin05g03980 125 Effector(V1) "Bcrpb11, similar to yeast RPB11, RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit [Source:SGD;Acc:S000005365]" Bcin05g03990 627 Protease//SignalP-noTM Bcap12, Aspartic proteinase Bcin05g04000 157 Effector(V1) Bcin05g04010 188 SignalP-noTM//Early secretome Polyketide cyclase SnoaL-like domain + NTF2-like domain Bcin05g04020 134 Effector(V1) NAD(P)-binding domain Bcin05g04030 652 yes MADS box transcription factor Bcmads1, MADS-box transcription_factor Bcin05g04040 1092 "Bctaf1, similar to yeast TAF1, TFIID subunit, involved in RNA pol II transcription initiation; possesses in vitro histone acetyltransferase activity but its role in vivo appears to be minor; involved in promoter binding and G1/S progression; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003506]" Bcin05g04050 459 "Bcdsd1, similar to yeast DSD1, D-serine dehydratase (aka D-serine ammonia-lyase); converts D-serine to pyruvate and ammonia by a reaction dependent on pyridoxal 5'-phosphate and zinc; may play a role in D-serine detoxification; L-serine is not a substrate [Source:SGD;Acc:S000003164]" Bcin05g04060 467 Actin family + Actin, conserved site Bcin05g04070 444 Protein kinase domain + Leucine-rich repeat + Leucine-rich repeat, typical subtype + Protein kinase-like domain + Protein kinase, ATP binding site + Leucine-rich repeat domain, L domain-like Bcin05g04080 348 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin05g04090 259 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin05g04100 285 Bcin05g04110 272 Effector(V1) Zinc finger, MYND-type Bcin05g04120 380 SignalP-noTM Protein of unknown function DUF4448 Bcin05g04130 160 Effector(V1) Bcin05g04140 63 Effector(V2) Bcin05g04150 431 "Bcmdm12, similar to yeast MDM12, Mitochondrial outer membrane protein, ERMES complex subunit; required for transmission of mitochondria to daughter cells; required for mitophagy; may influence import and assembly of outer membrane beta-barrel proteins; ERMES complex is often co-localized with peroxisomes and with concentrated areas of pyruvate dehydrogenase [Source:SGD;Acc:S000005369]" Bcin05g04160 236 "Bcvps28, similar to yeast VPS28, Component of the ESCRT-I complex; complex is involved in ubiquitin-dependent sorting of proteins into the endosome; conserved C-terminal domain interacts with ESCRT-III subunit Vps20p; other members include Stp22p, Srn2p, Vps28p, and Mvb12p [Source:SGD;Acc:S000005986]" Bcin05g04170 779 "Bcnoc2, similar to yeast NOC2, Protein involved in ribosome biogenesis; forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes; forms a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors; acts as part of a Mak21p-Noc2p-Rrp5p module that associates with nascent pre-rRNA during transcription and has a role in bigenesis of the large ribosomal subunit [Source:SGD;Acc:S000005732]" Bcin05g04180 859 Protein of unknown function DUF3419 + S-adenosyl-L-methionine-dependent methyltransferase Bcin05g04190 403 Protease//SignalP-noTM//Early secretome Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin05g04200 203 Bcin05g04210 313 SignalP-noTM Bcin05g04220 435 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin05g04230 213 "Bcvps60, similar to yeast VPS60, Protein involved in late endosome to vacuole transport; cytoplasmic and vacuolar membrane protein; required for normal filament maturation during pseudohyphal growth; may function in targeting cargo proteins for degradation; interacts with Vta1p [Source:SGD;Acc:S000002894]" Bcin05g04240 1150 SIT4 phosphatase-associated protein family Bcin05g04250 564 DnaJ homologue, subfamily C, member 28, conserved domain Bcin05g04260 969 Spindle associated Bcin05g04270 372 "Bclys1, similar to yeast LYS1, Saccharopine dehydrogenase (NAD+, L-lysine-forming); catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway; also has mRNA binding activity [Source:SGD;Acc:S000001473]" Bcin05g04280 594 CAZy : GT2 Nucleotide-diphospho-sugar transferases Bcin05g04290 517 CAZy : GT31 Bcin05g04300 498 CAZy : GT31 Bcin05g04310 483 Cation/H+ exchanger Bcin05g04320 238 Bcin05g04330 291 "Bcthg1, similar to yeast THG1, tRNAHis guanylyltransferase; adds a guanosine residue to the 5' end of tRNAH is after transcription and RNase P cleavage; can also catalyze reverse (3'-5') polymerization with certain substrates in a template-dependent reaction; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes [Source:SGD;Acc:S000003256]" Bcin05g04340 569 Protein kinase domain + Protein kinase-like domain Bcin05g04350 196 Effector(V2)|Effector(V1) Bcin05g04360 229 Effector(V2) RlpA-like double-psi beta-barrel domain Bcin05g04370 616 Phospholipase C, phosphatidylinositol-specific , X domain + PLC-like phosphodiesterase, TIM beta/alpha-barrel domain Bcin05g04380 139 Effector(V2)|Effector(V1) YjgF/Yer057p/UK114 family + Endoribonuclease L-PSP/chorismate mutase-like Bcin05g04390 445 Bcin05g04400 190 Bcin05g04410 330 Bcin05g04420 480 Protease "Bcmas1, similar to yeast MAS1, Beta subunit of the mitochondrial processing protease (MPP); essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins [Source:SGD;Acc:S000004153]" Bcin05g04430 192 Effector(V2) Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS Bcin05g04440 250 Bcin05g04450 243 Bcin05g04460 192 Bcin05g04470 281 Armadillo-like helical Bcin05g04480 776 "Bcpah1, similar to yeast PAH1, Mg2+-dependent phosphatidate (PA) phosphatase; dephosphorylates PA to yield diacylglycerol; responsible for de novo lipid synthesis and formation of lipid droplets; phosphorylation by Pho80p-Pho85p decreases catalytic activity and alters Pah1p localization and abundance; phosphorylation by protein kinase A decreases catalytic efficiency; dephosphorylation by Nem1p-Spo7p anchors Pah1p to the membrane increasing substrate catalysis; homologous to mammalian lipins 1 and 2 [Source:SGD;Acc:S000004775]" Bcin05g04490 1126 Fibronectin type III + Immunoglobulin-like fold Bcin05g04500 584 Bcin05g04510 346 U6 snRNA phosphodiesterase Usb1 Bcin05g04520 402 Pal1 cell morphology Bcin05g04530 1569 PAS domain + Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily + PAS fold + GAF domain-like Bcin05g04540 664 Platelet-activating factor acetylhydrolase + Alpha/Beta hydrolase fold Bcin05g04550 1006 Bcin05g04560 707 Ankyrin repeat + Ankyrin repeat-containing domain Bcin05g04570 578 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin05g04580 501 Bccat6, Catalase Bcin05g04590 436 Bcin05g04600 502 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA + S-adenosyl-L-methionine-dependent methyltransferase Bcin05g04610 453 Tryptophan synthase beta subunit-like PLP-dependent enzyme Bcin05g04620 424 O-methyltransferase, family 2 + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin05g04630 273 Protease "Bcdsc2, similar to yeast DSC2, Multi-transmembrane subunit of the DSC ubiquitin ligase complex; similar in sequence to rhomboid pseudoproteases Der1p and UBAC2 that function in ERAD; ortholog of fission yeast dsc2 [Source:SGD;Acc:S000005434]" Bcin05g04640 219 Effector(V1) Bcin05g04650 845 TEA/ATTS Bcin05g04660 838 "Bcmrd1, similar to yeast MRD1, Essential conserved small ribosomal subunit (40s) synthesis factor; component of the 90S preribosome; required for production of 18S rRNA and small ribosomal subunit; contains five consensus RNA-binding domains and binds to the pre-rRNA at two sites within the 18S region [Source:SGD;Acc:S000006316]" Bcin05g04670 97 Effector(V2)|Effector(V1) "Bcdyn2, similar to yeast DYN2, Cytoplasmic light chain dynein, microtubule motor protein; required for intracellular transport and cell division; involved in mitotic spindle positioning; forms complex with dynein intermediate chain Pac11p that promotes Dyn1p homodimerization, potentiates motor processivity; Dyn2p-Pac11p complex important for interaction of dynein motor complex with dynactin complex; acts as molecular glue to dimerize, stabilize Nup82-Nsp1-Nup159 complex module of cytoplasmic pore filaments [Source:SGD;Acc:S000002832]" Bcin05g04680 654 Winged helix-turn-helix DNA-binding domain Bcin05g04690 205 Effector(V2)|Effector(V1) Protein of unknown function DUF2237 Bcin05g04700 339 Ribonuclease III domain Bcin05g04710 300 UBA-like + Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote Bcin05g04720 128 Effector(V2)|Effector(V1)//Early secretome Enamine/imine deaminase YjgF-like + YjgF/Yer057p/UK114 family + Endoribonuclease L-PSP/chorismate mutase-like Bcin05g04730 631 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Calcium/calmodulin-dependent/calcium-dependent protein kinase Bcin05g04740 530 "Bcmtc1, similar to yeast MTC1, Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); mtc1 is synthetically lethal with cdc13-1 [Source:SGD;Acc:S000003659]" Bcin05g04750 925 Bcin05g04760 662 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin05g04770 429 SignalP-noTM LicD + Fukutin-related Bcin05g04780 514 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin05g04790 531 Permease, cytosine/purines, uracil, thiamine, allantoin + Purine-cytosine permease Bcin05g04800 61 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Bcin05g04810 176 Effector(V2)|Effector(V1) CinA, C-terminal Bcin05g04820 280 Bcin05g04830 123 Effector(V2)|Effector(V1) Bcin05g04840 691 "Bcdur3, similar to yeast DUR3, Plasma membrane transporter for both urea and polyamines; expression is highly sensitive to nitrogen catabolite repression and induced by allophanate, the last intermediate of the allantoin degradative pathway [Source:SGD;Acc:S000001008]" Bcin05g04850 1504 Paired amphipathic helix + Histone deacetylase interacting + Sin3, C-terminal Bcin05g04860 203 SignalP-noTM//Effector(V2)|Effector(V1) FAS1 domain Bcin05g04870 629 Cytochrome b5-like heme/steroid binding domain + FAD binding domain + Flavocytochrome c + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain + Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Bcin05g04880 561 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin05g04890 281 Bcin05g04900 796 Bcin05g04910 575 Pleckstrin homology-like domain Bcin05g04920 498 Major facilitator superfamily + Major facilitator superfamily domain Bcin05g04930 374 Taurine catabolism dioxygenase TauD/TfdA Bcin05g04940 214 Bcin05g04950 503 CAZy : GH28PCW pectin//SignalP-noTM Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin05g04960 321 Nitrilase/cyanide hydratase, conserved site + Carbon-nitrogen hydrolase Bcin05g04970 263 Bcin05g04980 435 Bcin05g04990 579 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin05g05000 418 Bcin05g05010 356 Bcin05g05020 381 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin05g05030 185 Effector(V1) "Bcpsf3, similar to yeast PSF3, Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p); complex is localized to DNA replication origins and implicated in assembly of the DNA replication machinery [Source:SGD;Acc:S000005506]" Bcin05g05040 230 Effector(V2)|Effector(V1) Bcsod4, Fe/Mn superoxide dismutase Bcin05g05050 95 Bcin05g05060 304 Bcin05g05070 575 "Bctim50, similar to yeast TIM50, Essential component of the TIM23 complex; acts as receptor for the translocase of the inner mitochondrial membrane (TIM23) complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel [Source:SGD;Acc:S000005984]" Bcin05g05080 1056 Bcin05g05090 436 CAZy : GH72FCW //Early secretome "Bcgas2, similar to yeast GAS2, 1,3-beta-glucanosyltransferase; involved with Gas4p in spore wall assembly; has similarity to Gas1p [Source:SGD;Acc:S000004335]" Bcin05g05100 295 Acyl-CoA N-acyltransferase + GNAT domain Bcin05g05110 227 SignalP-noTM Bcin05g05120 304 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin05g05130 133 Bcin05g05140 415 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin05g05150 333 NAD(P)-binding domain Bcin05g05160 336 SignalP-noTM Bcin05g05170 116 Effector(V2)|Effector(V1) GTP cyclohydrolase 1 type 2/Nif3 Bcin05g05180 514 Mannose-6-phosphate receptor binding domain + Glucosidase II beta subunit-like Bcin05g05190 674 Bcin05g05200 132 Bcin05g05210 236 Effector(V2)|Effector(V1) Bcin05g05220 545 Acyl-CoA N-acyltransferase + Siderophore biosynthesis protein, conserved domain Bcin05g05230 344 Bcin05g05240 514 Coiled-coil domain containing protein 109, C-terminal Bcin05g05250 268 "Bctaf9, similar to yeast TAF9, Subunit (17 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3 [Source:SGD;Acc:S000004849]" Bcin05g05260 874 "Bchis4, similar to yeast HIS4, Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase; phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis [Source:SGD;Acc:S000000535]" Bcin05g05270 417 Bcin05g05280 449 "Bcpex13, similar to yeast PEX13, Peroxisomal importomer complex component; integral peroxisomal membrane protein required for docking and translocation of peroxisomal matrix proteins; interacts with the PTS1 signal recognition factor Pex5p and the PTS2 signal recognition factor Pex7p; forms a complex with Pex14p and Pex17p [Source:SGD;Acc:S000004181]" Bcin05g05290 320 NmrA-like domain + NAD(P)-binding domain Bcin05g05300 736 Bcin05g05310 511 SignalP-noTM "Bctos1, similar to yeast TOS1, Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C [Source:SGD;Acc:S000000366]" Bcin05g05320 348 SignalP-noTM Bcin05g05330 565 UV radiation resistance protein/autophagy-related protein 14 Bcin05g05340 217 Bcin05g05350 203 Protein of unknown function DUF3807 Bcin05g05360 379 Bcin05g05370 593 LMBR1-like membrane protein Bcin05g05380 1447 "Bccft1, similar to yeast CFT1, RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF [Source:SGD;Acc:S000002709]" Bcin05g05390 702 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin05g05400 335 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin05g05410 329 "Bcrpp1, similar to yeast RPP1, Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000001104]" Bcin05g05420 226 SignalP-noTM Bcin05g05430 337 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal + Protein of unknown function DUF1295 Bcin05g05440 151 Effector(V2)|Effector(V1) Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin05g05450 246 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin05g05460 301 "Bcdst1, similar to yeast DST1, General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress [Source:SGD;Acc:S000003011]" Bcin05g05470 711 Bcin05g05480 512 Bcin05g05490 940 Homeodomain-like + Centromere protein Scm3/HJURP Bcin05g05500 501 "Bcvps30, similar to yeast VPS30, Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy and Complex II is required for vacuolar protein sorting; required for overflow degradation of misfolded proteins when ERAD is saturated; C-terminus has a novel globular fold that is essential for autophagy through the targeting of the PI3-kinase complex I to the pre-autophagosomal structure; ortholog of the higher eukaryotic gene Beclin 1 [Source:SGD;Acc:S000006041]" Bcin05g05510 79 Bcin05g05520 1316 "Bcrad50, similar to yeast RAD50, Subunit of MRX complex with Mre11p and Xrs2p; complex is involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000005194]" Bcin05g05530 509 yes GATA zinc finger transcription factor Bcwcl2, GATA zinc finger transcription factor, White collar-like 2, potential blue light sensor Bcin05g05540 699 Bcin05g05550 149 Effector(V2)|Effector(V1) Enamine/imine deaminase YjgF-like + YjgF/Yer057p/UK114 family + Endoribonuclease L-PSP/chorismate mutase-like Bcin05g05560 319 Crotonase superfamily + ClpP/crotonase-like domain Bcin05g05570 167 RNA polymerase II, Rpb4 + RNA polymerase II, Rpb4, core + HRDC-like Bcin05g05580 446 "Bcprs5, similar to yeast PRS5, 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000005422]" Bcin05g05590 355 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin05g05600 1768 "Bclte1, similar to yeast LTE1, Protein similar to GDP/GTP exchange factors; without detectable GEF activity; required for asymmetric localization of Bfa1p at daughter-directed spindle pole bodies and for mitotic exit at low temperatures [Source:SGD;Acc:S000000022]" Bcin05g05610 203 Effector(V2)|Effector(V1) Small GTPase superfamily + P-loop containing nucleoside triphosphate hydrolase Bcin05g05620 575 "Bcdeg1, similar to yeast DEG1, tRNA:pseudouridine synthase; introduces pseudouridines at position 38 or 39 in tRNA; also responsible for pseudouracil modification of some mRNAs; important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm; non-essential for viability [Source:SGD;Acc:S000001895]" Bcin05g05630 498 SM cluster PAX-like Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin05g05640 360 SM cluster PAX-like Bcin05g05650 229 SM cluster PAX-like Bcin05g05660 243 SM cluster PAX-like Bcin05g05670 338 SM cluster PAX-like (KE) Bcpax1, PaxC-like, secondary metabolism key enzyme Bcin05g05680 557 SM cluster PAX-like Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin05g05690 330 SM cluster PAX-like Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin05g05700 825 "Bcsec18, similar to yeast SEC18, AAA ATPase and SNARE disassembly chaperone; required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, autophagy, and protein secretion; releases Sec17p from SNAP complexes; has similarity to mammalian N-ethylmaleimide-sensitive factor (NSF) [Source:SGD;Acc:S000000284]" Bcin05g05710 340 CBF1-interacting co-repressor CIR, N-terminal domain Bcin05g05720 197 Bcin05g05730 245 Bcin05g05740 626 "Bcspb4, similar to yeast SPB4, Putative ATP-dependent RNA helicase; nucleolar protein required for synthesis of 60S ribosomal subunits at a late step in the pathway; sediments with 66S pre-ribosomes in sucrose gradients [Source:SGD;Acc:S000001894]" Bcin05g05750 394 "Bcdgk1, similar to yeast DGK1, Diacylglycerol kinase; localized to the endoplasmic reticulum (ER); overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation; contains a CTP transferase domain [Source:SGD;Acc:S000005838]" Bcin05g05760 190 Effector(V2)|Effector(V1) Uncharacterised domain KxDL Bcin05g05770 226 Effector(V1) GPI-GlcNAc transferase complex, PIG-H component, conserved domain Bcin05g05780 234 Ubiquitin-related domain Bcin05g05790 568 "Bcnop58, similar to yeast NOP58, Protein involved in producing mature rRNAs and snoRNAs; involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA [Source:SGD;Acc:S000005837]" Bcin05g05800 365 "Bcvma6, similar to yeast VMA6, Subunit d of the V0 integral membrane domain of V-ATPase; part of the electrogenic proton pump found in the endomembrane system; required for V1 domain assembly on the vacuolar membrane; the V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase) has five subunits [Source:SGD;Acc:S000004439]" Bcin05g05810 319 Ribosomal protein S15 + Ribosomal protein S15, bacterial-type + S15/NS1, RNA-binding Bcin05g05820 296 Ribosomal protein S2 + Ribosomal protein S2, eukaryotic/archaeal + Ribosomal protein S2, conserved site + Ribosomal protein S2, flavodoxin-like domain + Ribosomal protein S2, eukaryotic + 40S ribosomal protein SA, C-terminal domain Bcin05g05830 649 Protease//SignalP-noTM Peptidase S8/S53 domain + Proteinase inhibitor, propeptide + Peptidase S53, propeptide + Sedolisin domain Bcin05g05840 413 Opioid growth factor receptor (OGFr) conserved domain Bcin05g05850 465 Protease Creatinase, N-terminal + Peptidase M24, structural domain + Creatinase/Aminopeptidase P, N-terminal + Creatinase/Aminopeptidase P/Spt16, N-terminal Bcin05g05860 441 Ornithine/DAP/Arg decarboxylase + Ornithine decarboxylase + Alanine racemase/group IV decarboxylase, C-terminal + Orn/DAP/Arg decarboxylase 2, C-terminal + Orn/DAP/Arg decarboxylase 2, N-terminal + Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site + Orn/DAP/Arg decarboxylase 2, conserved site + PLP-binding barrel Bcin05g05870 1025 Protease "Bccym1, similar to yeast CYM1, Lysine-specific metalloprotease of the pitrilysin family; metalloprotease of the intermembrane space; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology [Source:SGD;Acc:S000002838]" Bcin05g05880 462 Effector(V2)|Effector(V1) Taxilin family Bcin05g05890 183 Effector(V2)|Effector(V1) Bcin05g05900 441 yes Protease//SignalP-noTM//Early secretome Bcap5, Aspartic proteinase Bcin05g05910 397 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin05g05920 147 Effector(V1) Bcin05g05930 610 CAZy : AA7,CBM18 Chitin-binding, type 1 + FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin05g05940 446 3-hydroxyisobutyrate dehydrogenase-related, conserved site + 6-phosphogluconate dehydrogenase, NADP-binding + 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + NAD(P)-binding domain + 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain Bcin05g05950 612 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin05g05960 482 Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin05g05970 854 V-type ATPase, V0 complex, 116kDa subunit family + ATPase, V0 complex, subunit 116kDa, eukaryotic Bcin05g05980 442 Bcin05g05990 109 Bcin05g06000 342 Bcin05g06010 86 Effector(V1) Bcin05g06020 487 CAZy : GH10,CBM1PCW hemicellulose//SignalP-noTM//Early secretome BcXyn10B, Xylanase of family GH10 (Garcia et al., 2017) Bcin05g06030 579 "Bcmsm1, similar to yeast MSM1, Mitochondrial methionyl-tRNA synthetase (MetRS); functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p [Source:SGD;Acc:S000003403]" Bcin05g06040 172 Effector(V2)|Effector(V1) Nuclear transport factor 2, eukaryote + Nuclear pore RNA shuttling protein Mtr2 + NTF2-like domain Bcin05g06050 1053 Bcin05g06060 181 Effector(V2) Bcin05g06070 83 Effector(V2)|Effector(V1) "Bcrpl38, similar to yeast RPL38, Ribosomal 60S subunit protein L38; homologous to mammalian ribosomal protein L38, no bacterial homolog [Source:SGD;Acc:S000004317]" Bcin05g06080 497 Bcin05g06090 370 Domain of unknown function SprT-like Bcin05g06100 638 F-box domain + WD40/YVTN repeat-like-containing domain Bcin05g06110 538 "Bcchk1, similar to yeast CHK1, Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase [Source:SGD;Acc:S000000478]" Bcin05g06120 182 Effector(V1) "Bcubc11, similar to yeast UBC11, Ubiquitin-conjugating enzyme; most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2 [Source:SGD;Acc:S000005866]" Bcin05g06130 125 Effector(V2)|Effector(V1) Ribosomal protein L31e + Ribosomal protein L31e domain Bcin05g06140 378 "Bcrax1, similar to yeast RAX1, Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has similarity to members of the insulin-related peptide superfamily [Source:SGD;Acc:S000005827]" Bcin05g06150 292 Proteasome component (PCI) domain Bcin05g06160 1159 Bcin05g06170 219 Cys2His2 transcription factor//SM cluster PKS15//Effector(V2)|Effector(V1) Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin05g06180 588 SM cluster PKS15 Bcin05g06190 724 Zn2/Cys6 + fungal trans transcription factor//SM cluster PKS15 Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin05g06200 370 SM cluster PKS15 Glucose/ribitol dehydrogenase + GroES (chaperonin 10)-like + NAD(P)-binding domain Bcin05g06210 280 SM cluster PKS15 S-adenosyl-L-methionine-dependent methyltransferase Bcin05g06220 2126 SM cluster PKS15 (KE) Bcpks15, Polyketide synthase Bcin05g06230 241 Effector(V2)|Effector(V1) NACHT-NTPase and P-loop NTPases, N-terminal domain Bcin05g06240 549 Protease Peptidase M12A, astacin + Peptidase, metallopeptidase + H-type lectin domain + Metallopeptidase, catalytic domain Bcin05g06250 343 Bcin05g06260 69 Bcin05g06270 1001 Bcin05g06280 350 yes Effector(V2) GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin05g06290 1569 WD40 repeat + GPI inositol-deacylase PGAP1-like + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase + Alpha/Beta hydrolase fold Bcin05g06300 368 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin05g06310 370 "Bcrpc34, similar to yeast RPC34, RNA polymerase III subunit C34; interacts with TFIIIB70 and is a key determinant in pol III recruitment by the preinitiation complex [Source:SGD;Acc:S000005286]" Bcin05g06320 223 yes Effector(V2)|Effector(V1) Bcp1, Peptidyl-prolylisomerase, cyclophilin A Bcin05g06330 511 ENTH/VHS + ENTH domain Bcin05g06340 1050 Tetratricopeptide-like helical domain + P-loop containing nucleoside triphosphate hydrolase Bcin05g06350 711 Ankyrin repeat + Domain of unknown function DUF676, lipase-like + Ankyrin repeat-containing domain + Alpha/Beta hydrolase fold Bcin05g06360 590 Galactose oxidase/kelch, beta-propeller + Kelch-type beta propeller Bcin05g06370 231 Effector(V2)|Effector(V1) Bcin05g06380 251 Bcin05g06390 201 Effector(V2)|Effector(V1) Bcin05g06400 707 Heterokaryon incompatibility Bcin05g06410 1032 "Bcmsb1, similar to yeast MSB1, Protein of unknown function; may be involved in positive regulation of 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway; multicopy suppressor of temperature-sensitive mutations in CDC24 and CDC42, and of mutations in BEM4; potential Cdc28p substrate; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005714]" Bcin05g06420 176 Bcin05g06430 294 Formyl transferase, N-terminal + ACT domain + Formyltetrahydrofolate deformylase Bcin05g06440 517 "Bchrt3, similar to yeast HRT3, Putative SCF-ubiquitin ligase F-box protein; based on both genetic and physical interactions and sequence similarity; identified in association with Cdc53p, Skp1p and Ubi4 in large and small-scale studies [Source:SGD;Acc:S000004087]" Bcin05g06450 451 Transporter "Bcmtm1, similar to yeast MTM1, Mitochondrial protein of the mitochondrial carrier family; high affinity pyridoxal 5′-phosphate transporter; involved in mitochondrial iron homeostasis and in activating mitochondrial Sod2p by facilitating insertion of an essential manganese cofactor [Source:SGD;Acc:S000003489]" Bcin05g06460 309 "Bcung1, similar to yeast UNG1, Uracil-DNA glycosylase; required for repair of uracil in DNA formed by spontaneous cytosine deamination; efficiently excises uracil from single-stranded DNA in vivo; not required for strand-specific mismatch repair; cell-cycle regulated, expressed in late G1; localizes to mitochondria and nucleus [Source:SGD;Acc:S000004483]" Bcin05g06470 263 Bcin05g06480 117 Effector(V2)|Effector(V1) "Bcsmf1, similar to yeast SMF1, Divalent metal ion transporter; broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins [Source:SGD;Acc:S000005482]" Bcin05g06490 151 Polyketide cyclase SnoaL-like domain + NTF2-like domain Bcin05g06500 729 Phytanoyl-CoA dioxygenase Bcin05g06510 823 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Cellobiose dehydrogenase, cytochrome domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin05g06520 931 Bcin05g06530 281 Bcin05g06540 474 Pex, N-terminal + Zinc finger, RING/FYVE/PHD-type Bcin05g06550 668 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin05g06560 381 Bcin05g06570 327 Bcin05g06580 328 Bcin05g06590 244 Effector(V1) Zinc finger, MYND-type Bcin05g06600 307 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin05g06610 530 Transporter Sugar/inositol transporter + General substrate transporter + Major facilitator superfamily domain Bcin05g06620 266 Effector(V2)|Effector(V1) Bcin05g06630 556 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin05g06640 239 Serralysin-like metalloprotease, C-terminal Bcin05g06650 343 Bcin05g06660 228 Effector(V2) Bcin05g06670 260 Bcin05g06680 140 Effector(V1) Protein of unknown function DUF1754, eukaryotic Bcin05g06690 518 Bcin05g06700 988 Rho GTPase-activating protein domain + Rho GTPase activation protein Bcin05g06710 90 Effector(V2) "Bctim9, similar to yeast TIM9, Essential protein of the mitochondrial intermembrane space; forms a complex with Tim10p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane [Source:SGD;Acc:S000007256]" Bcin05g06720 1872 Nucleoporin Nup188 Bcin05g06730 764 Protease N-(5'phosphoribosyl) anthranilate isomerase (PRAI) + Indole-3-glycerol phosphate synthase, conserved site + Anthranilate synthase/para-aminobenzoate synthase like domain + Ribulose-phosphate binding barrel + Aldolase-type TIM barrel + Indole-3-glycerol phosphate synthase + Anthranilate synthase component 2 + Glutamine amidotransferase + Class I glutamine amidotransferase-like Bcin05g06740 496 BRCT domain Bcin05g06750 322 Vesicle transport protein, Use1 Bcin05g06760 277 Bcin05g06770 353 yes Signaling pathway Bcg1, Heterotrimeric Galpha subunit,conidiation-associated gene, similar to FadA (AN0651.3) Aspergillus nidulans gene Bcin05g06780 181 Bcin05g06790 92 Effector(V2)|Effector(V1) Protein of unknown function DUF543 Bcin05g06800 719 "Bcrok1, similar to yeast ROK1, RNA-dependent ATPase; involved in pre-rRNA processing at sites A0, A1, and A2, and in control of cell cycle progression; contains two upstream open reading frames (uORFs) in 5' untranslated region which regulate translation [Source:SGD;Acc:S000003139]" Bcin05g06810 333 Small GTPase superfamily + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin05g06820 263 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin05g06830 297 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Chitin-binding, domain 3 Bcin05g06840 254 Effector(V2)|Effector(V1) ATPase, F0 complex, subunit A Bcin05g06842 547 "Bcvcx1, similar to yeast VCX1, Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity; involved in control of cytosolic Ca2+ and K+ concentrations; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter [Source:SGD;Acc:S000002286]" Bcin05g06850 828 Heterokaryon incompatibility Bcin05g06860 898 Bcin05g06870 352 Beta-lactamase-like Bcin05g06880 1197 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin05g06890 500 "Bcgwt1, similar to yeast GWT1, Protein involved in the inositol acylation of GlcN-PI; the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) forms glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors [Source:SGD;Acc:S000003627]" Bcin05g06900 373 Bcin05g06910 514 CAZy : GT2 Nucleotide-diphospho-sugar transferases Bcin05g06920 369 Bcin05g06930 484 CAZy : GT2 Glycosyltransferase 2-like + Nucleotide-diphospho-sugar transferases Bcin05g06940 1118 CAZy : GHnc //SignalP-noTM Glycoside hydrolase, family 16 + Acyltransferase 3 + Concanavalin A-like lectin/glucanase domain Bcin05g06950 447 Bcin05g06960 329 Ribonuclease H-like domain Bcin05g06970 372 Bcin05g06980 521 LGFP Bcin05g06990 443 Bcin05g07000 705 AMP-dependent synthetase/ligase + AMP-binding, conserved site Bcin05g07010 628 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin05g07020 517 Transporter Amino acid/polyamine transporter I Bcin05g07030 688 Copper amine oxidase + Copper amine oxidase, C-terminal + Copper amine oxidase, N-terminal Bcin05g07040 409 CAZy : GH64FCW Beta-1,3-glucanase, N-terminal Bcin05g07050 728 Clr5 domain Bcin05g07060 602 "Bcdld1, similar to yeast DLD1, D-lactate dehydrogenase; oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane [Source:SGD;Acc:S000002333]" Bcin05g07070 610 "Bcamd2, similar to yeast AMD2, Putative amidase [Source:SGD;Acc:S000002650]" Bcin05g07080 218 Effector(V2)|Effector(V1) Bcin05g07090 620 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin05g07100 365 SignalP-noTM Pirin, N-terminal domain + Pirin, C-terminal domain + RmlC-like cupin domain + RmlC-like jelly roll fold Bcin05g07110 805 DnaJ domain Bcin05g07120 277 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin05g07130 586 "Bcmsk1, similar to yeast MSK1, Mitochondrial lysine-tRNA synthetase; required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria and for aminoacylation of mitochondrially encoded tRNA(Lys) [Source:SGD;Acc:S000005017]" Bcin05g07140 99 Effector(V2)|Effector(V1) "Bctim10, similar to yeast TIM10, Essential protein of the mitochondrial intermembrane space; forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane [Source:SGD;Acc:S000003530]" Bcin05g07150 910 Bcin05g07160 405 "Bcrmd5, similar to yeast RMD5, Component of GID Complex that confers ubiquitin ligase (U3) activity; necessary for polyubiquitination and degradation of the gluconeogenic enzyme fructose-1,6-bisphosphatase; forms dimer with Fyv10p that is then recruited to GID Complex by Gid8p; also required for sporulation; conserved protein that has a degenerate RING finger domain [Source:SGD;Acc:S000002663]" Bcin05g07170 499 Protein phosphatase 4 core regulatory subunit R2 Bcin05g07180 341 Bcin05g07190 240 Protease//Effector(V2)|Effector(V1)//Early secretome ThiJ/PfpI + Class I glutamine amidotransferase-like Bcin05g07200 179 Effector(V2)|Effector(V1) Bcin05g07210 181 Bcin05g07220 579 "Bcted1, similar to yeast TED1, Conserved phosphoesterase domain-containing protein; acts together with Emp24p/Erv25p in cargo exit from the ER; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) [Source:SGD;Acc:S000001301]" Bcin05g07230 781 Protein of unknown function DUF1399 Bcin05g07240 1583 PAS domain + PAC motif + Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily + PAS fold-3 Bcin05g07250 570 Heterokaryon incompatibility Bcin05g07260 152 Effector(V1) Bcin05g07270 888 Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + PA14 + Glycoside hydrolase superfamily + Glycoside hydrolase, family 3, active site + Fibronectin type III-like domain Bcin05g07280 208 Effector(V2)|Effector(V1) Domain of unknown function DUF202 Bcin05g07290 569 Cation efflux protein + Cation efflux protein transmembrane domain Bcin05g07300 348 SignalP-noTM Bcin05g07310 211 Effector(V2)|Effector(V1) Thioredoxin-like fold Bcin05g07320 249 Effector(V2)|Effector(V1) Phox homologous domain Bcin05g07330 195 SignalP-noTM Bcin05g07340 450 CDP-alcohol phosphatidyltransferase + Choline/ethanolamine phosphotransferase Bcin05g07350 783 IQ motif, EF-hand binding site Bcin05g07360 370 SignalP-noTM Domain of unknown function DUF3844 Bcin05g07370 427 Bcin05g07380 359 Bcin05g07390 389 Triose-phosphate transporter domain Bcin05g07400 896 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin05g07410 201 "Bccia2, similar to yeast CIA2, Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at a late step of Fe-S cluster assembly; forms the CIA targeting complex with Cia1p and Met18p that directs Fe-S cluster incorporation into a subset of proteins involved in methionine biosynthesis, DNA replication and repair, transcription, and telomere maintenance; ortholog of human FAM96B [Source:SGD;Acc:S000001164]" Bcin05g07420 998 "Bcsnu114, similar to yeast SNU114, GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2 [Source:SGD;Acc:S000001656]" Bcin05g07430 400 "Bcerg10, similar to yeast ERG10, Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase); cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis [Source:SGD;Acc:S000005949]" Bcin05g07440 1074 "Bckre33, similar to yeast KRE33, Protein required for biogenesis of the small ribosomal subunit; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance; essential gene; NAT10, the human homolog, implicated in several types of cancer and premature aging. [Source:SGD;Acc:S000005076]" Bcin05g07450 160 Rhodanese-like domain Bcin05g07460 85 Effector(V1) "Bcsmx2, similar to yeast SMX2, Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G [Source:SGD;Acc:S000002965]" Bcin05g07470 465 GC-rich sequence DNA-binding factor + Pre-mRNA-splicing factor Ntr2 Bcin05g07480 752 "Bccdc1, similar to yeast CDC1, Putative lipid phosphatase of the endoplasmic reticulum; shows Mn2+ dependence and may affect Ca2+ signaling; mutants display actin and general growth defects and pleiotropic defects in cell cycle progression and organelle distribution [Source:SGD;Acc:S000002590]" Bcin05g07490 363 Beta-lactamase-like Bcin05g07500 563 Amidase + Amidase signature domain Bcin05g07510 291 S-adenosyl-L-methionine-dependent methyltransferase Bcin05g07520 581 Transporter Bchex3, Similar to MFS sugar transporter Bcin05g07530 457 Bcin05g07540 588 Bcin05g07550 352 Bcin05g07560 168 Bcin05g07570 152 Effector(V1) RNA recognition motif domain + RNA-binding motif protein 8 + Nucleotide-binding alpha-beta plait domain Bcin05g07580 374 Bcin05g07590 210 Glucose-methanol-choline oxidoreductase, N-terminal + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin05g07600 503 yes Transporter Bcmfs2, Major facilitator superfamily transporter Bcin05g07610 778 Bcin05g07620 631 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin05g07630 208 SignalP-noTM Bcin05g07640 518 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin05g07650 595 F-box domain Bcin05g07660 555 Bcin05g07670 361 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin05g07680 144 Bcin05g07690 567 CAZy : GH76FCW //SignalP-noTM Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase Bcin05g07700 353 ER lumen protein retaining receptor Bcin05g07710 170 Bcin05g07720 132 Bcin05g07730 199 Effector(V1) Bcin05g07740 252 Bcin05g07750 129 Effector(V1) Bcin05g07760 166 Effector(V2)|Effector(V1) Bcin05g07770 296 BTB/POZ-like Bcin05g07790 253 BTB/POZ-like + BTB/POZ fold Bcin05g07800 348 Bcin05g07810 511 BTB/POZ-like + BTB/POZ fold Bcin05g07820 406 Bcin05g07830 106 Effector(V1) Bcin05g07840 806 Protease "Bcvps70, similar to yeast VPS70, Protein of unknown function involved in vacuolar protein sorting [Source:SGD;Acc:S000003887]" Bcin05g07850 620 Transporter Tetracycline resistance protein, TetA/multidrug resistance protein MdtG + Major facilitator superfamily + Major facilitator superfamily domain Bcin05g07860 429 Bcin05g07870 128 Effector(V2)|Effector(V1) Bcin05g07890 470 Bcin05g07900 1009 "Bckip3, similar to yeast KIP3, Kinesin-related antiparallel sliding motor protein; involved in mitotic spindle positioning; sliding activity promotes bipolar spindle assembly and maintenance of genome stability; inhibits spindle elongation, destabilizing late anaphase spindle microtubules that polymerize beyond the midzone [Source:SGD;Acc:S000003184]" Bcin05g07910 999 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin05g07920 205 Effector(V2)|Effector(V1) "Bccgi121, similar to yeast CGI121, Component of the EKC/KEOPS complex; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription; Cgi121p is dispensable for tRNA modification; other complex members are Bud32p, Kae1p, Pcc1p, and Gon7p [Source:SGD;Acc:S000004500]" Bcin05g07930 326 BTB/POZ fold Bcin05g07940 322 BTB/POZ fold Bcin05g07950 369 BTB/POZ-like + BTB/POZ fold Bcin05g07960 375 Six-bladed beta-propeller, TolB-like + SMP-30/Gluconolactonase/LRE-like region Bcin05g07970 352 BTB/POZ-like + BTB/POZ fold Bcin05g07980 404 CAZy : GT32 Glycosyltransferase, DXD sugar-binding motif Bcin05g07990 563 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin05g08000 180 Conserved hypothetical protein CHP02464 Bcin05g08010 107 Bcin05g08020 480 NUDIX hydrolase domain + NUDIX hydrolase domain-like Bcin05g08030 182 Bcin05g08040 233 Effector(V2)|Effector(V1) Bcin05g08050 512 Proline dehydrogenase domain + Proline oxidase + FAD-linked oxidoreductase-like Bcin05g08060 658 yes Bccry1, Cryptochrome-like, potential blue light sensor Bcin05g08070 88 Effector(V2)|Effector(V1) Ribosomal protein S21e + Ribosomal protein S21e, conserved site Bcin05g08080 936 Structure-specific endonuclease subunit Slx4 + Structure-specific endonuclease subunit Slx4, ascomycetes Bcin05g08090 181 SignalP-noTM Bcin05g08100 224 Bcin05g08110 649 "Bcmae1, similar to yeast MAE1, Mitochondrial malic enzyme; catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids [Source:SGD;Acc:S000001512]" Bcin05g08120 482 Cys2His2 transcription factor//Effector(V2)|Effector(V1) Zinc finger, BED-type + Zinc finger, C2H2 + Zinc finger, C2H2-like Bcin05g08130 1167 CAZy : GH115PCW pectin//SignalP-noTM Chitobiase/beta-hexosaminidase domain 2-like + Glycosyl hydrolase family 115 Bcin05g08140 1633 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter, conserved site + ABC transporter A, ABCA + P-loop containing nucleoside triphosphate hydrolase Bcin05g08150 108 Bcin05g08160 445 GDP-fucose protein O-fucosyltransferase Bcin05g08170 557 SM cluster CAR ter Bcrco1, Resveratrol cleavage oxygenase 1 Bcin05g08180 648 Zn2/Cys6 transcription factor + Cys2His2 + Fungal_trans Zn(2)-C6 fungal-type DNA-binding domain + Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin05g08190 443 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin05g08200 433 Bcin05g08210 385 Bcin05g08220 139 Bcin05g08230 322 CAZy : AA9 //SignalP-noTM Glycoside hydrolase, family 61 Bcin05g08240 457 CAZy : GH28PCW pectin//SignalP-noTM//Early secretome Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin05g08250 423 Bcin05g08260 83 Bcin05g08270 635 FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin05g08280 549 CBS domain + IMP dehydrogenase/GMP reductase + Inosine-5'-monophosphate dehydrogenase + Aldolase-type TIM barrel + IMP dehydrogenase / GMP reductase, conserved site Bcin05g08290 1837 yes Bciqg1, Fungal IQGAP homolog Bcin05g08300 346 Bcin05g08310 379 Bcin05g08320 175 Effector(V2)|Effector(V1) Rieske [2Fe-2S] iron-sulphur domain Bcin05g08330 272 CAZy : CE12PCW hemicellulose or pectin//SignalP-noTM SGNH hydrolase-type esterase domain Bcin05g08340 812 Oligopeptide transporter, OPT superfamily Bcin05g08350 159 Effector(V2)|Effector(V1) Bcin05g08360 261 "Bcski6, similar to yeast SKI6, Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp41p (EXOSC4) [Source:SGD;Acc:S000003427]" Bcin05g08370 507 SignalP-noTM Thioredoxin-like fold + Thioredoxin domain + Thioredoxin, conserved site Bcin05g08380 439 Vacuolar protein sorting-associate protein Vta1/Callose synthase, N-terminal domain Bcin05g08390 348 SM cluster PKS21 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin05g08400 2571 SM cluster PKS21 (KE) Bcpks21, Polyketide synthase Bcin05g08410 324 Bcin05g08420 1067 Bcin06g00010 167 SignalP-noTM//Effector(V2) Bcin06g00020 105 Bcin06g00022 426 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin06g00024 285 Beta-lactamase-like Bcin06g00026 431 yes Major facilitator superfamily + Major facilitator superfamily domain Bcin06g00028 539 Beta-lactamase-like + SCP2 sterol-binding domain + Alkyl sulfatase dimerisation domain + Alkyl sulfatase, C-terminal Bcin06g00030 256 BTB/POZ-like + BTB/POZ fold Bcin06g00040 140 Bcin06g00050 785 Alpha-N-acetylglucosaminidase + Alpha-N-acetylglucosaminidase, N-terminal + Alpha-N-acetylglucosaminidase, C-terminal + Alpha-N-acetylglucosaminidase, tim-barrel domain Bcin06g00060 265 Bcin06g00070 121 Bcin06g00080 385 Bcin06g00090 153 Effector(V2)|Effector(V1) Bcin06g00100 475 Bcin06g00110 287 Effector(V2) Phytanoyl-CoA dioxygenase Bcin06g00120 769 Oligopeptide transporter, OPT superfamily Bcin06g00130 790 Oligopeptide transporter, OPT superfamily Bcin06g00140 563 AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain Bcin06g00150 562 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin06g00160 346 S-adenosyl-L-methionine-dependent methyltransferase Bcin06g00170 177 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin06g00180 152 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin06g00190 188 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin06g00200 873 Bcin06g00210 377 Bcin06g00220 343 Bcin06g00230 235 Effector(V2) GNAT domain + Acyl-CoA N-acyltransferase Bcin06g00240 465 yes Bchbf1, Hyphal branching-related factor 1 Bcin06g00250 318 Bcin06g00260 572 "Bcssz1, similar to yeast SSZ1, Hsp70 protein that interacts with Zuo1p (a DnaJ homolog); interacts with Zuo1p to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP [Source:SGD;Acc:S000001106]" Bcin06g00270 243 Effector(V2)|Effector(V1) "Bcrrp40, similar to yeast RRP40, Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain both S1 and KH RNA binding domains; has similarity to human hRrp40p (EXOSC3) [Source:SGD;Acc:S000005502]" Bcin06g00280 200 SignalP-noTM Bcin06g00290 407 Bcin06g00300 140 Effector(V1) Bcin06g00310 187 Effector(V1) Bcin06g00320 193 SignalP-TM//Effector(V1) Cell wall galactomannoprotein Bcin06g00330 632 Protease//SignalP-noTM//Early secretome Peptidase S8/S53 domain + Proteinase inhibitor, propeptide + Peptidase S53, propeptide + Peptidase S8, subtilisin, Ser-active site + Sedolisin domain Bcin06g00340 2239 SignalP-TM Zinc finger, ZZ-type + Ankyrin repeat + Ankyrin repeat-containing domain Bcin06g00350 546 CAZy : GT71 Alpha-mannosyltransferase + Nucleotide-diphospho-sugar transferases Bcin06g00360 1517 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin06g00365 87 Bcin06g00370 369 S-adenosyl-L-methionine-dependent methyltransferase Bcin06g00380 161 Ribosomal protein S17 + Nucleic acid-binding, OB-fold + Ribosomal protein S17, conserved site + Ribosomal protein S17, archaeal/eukaryotic + 40S ribosomal protein S11, N-terminal Bcin06g00390 1550 "Bcspc105, similar to yeast SPC105, Subunit of a kinetochore-microtubule binding complex; complex bridges centromeric heterochromatin and kinetochore MAPs and motors; required for sister chromatid bi-orientation and kinetochore binding of SAC components; complex also includes Kre28p; modified by sumoylation [Source:SGD;Acc:S000003061]" Bcin06g00400 360 SignalP-noTM Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin06g00410 514 Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin06g00420 353 SignalP-noTM Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin06g00430 1558 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin06g00440 738 "Bccac2, similar to yeast CAC2, Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p; chromatin assembly by CAF-1 is important for multiple processes including silencing at telomeres, mating type loci, and rDNA; maintenance of kinetochore structure, deactivation of the DNA damage checkpoint after DNA repair, chromatin dynamics during transcription; and repression of divergent transcription; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000004570]" Bcin06g00450 145 yes SignalP-noTM//Effector(V1) Bhl1, Hydrophobin-like Bcin06g00460 799 CAZy : GT1 UDP-glucuronosyl/UDP-glucosyltransferase + Glycosyltransferase family 28, N-terminal domain Bcin06g00470 276 RTA-like protein Bcin06g00480 321 CAZy : AA9,CBM1 //SignalP-noTM Cellulose-binding domain, fungal + Glycoside hydrolase, family 61 Bcin06g00490 398 CAZy : GH12PCW cellulose//SignalP-noTM BcXYG2, secreted Xyloglucanase 2 Bcin06g00500 178 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Phosphoglycerate/bisphosphoglycerate mutase, active site + Histidine phosphatase superfamily Bcin06g00510 98 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Bhp3, Hydrophobin class II Bcin06g00520 249 SignalP-noTM//Effector(V1) Bcin06g00530 269 Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin06g00540 140 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin06g00550 202 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bccdi1, Cell Death Inducing 1 Bcin06g00560 871 Bcin06g00570 790 Bcin06g00580 830 CAZy : GH92FCW //Early secretome Six-hairpin glycosidase-like + Glycosyl hydrolase family 92 + Glycoside hydrolase-type carbohydrate-binding, subgroup Bcin06g00590 1341 XPG/Rad2 endonuclease, eukaryotes + Ubiquitin interacting motif + XPG/Rad2 endonuclease + XPG N-terminal + XPG-I domain + Helix-hairpin-helix motif, class 2 + XPG conserved site + 5'-3' exonuclease, C-terminal domain + PIN domain-like Bcin06g00600 144 Ribonucleoprotein LSM domain + Like-Sm (LSM) domain + LSM domain containing 1 Bcin06g00610 357 Eisosome component PIL1/LSP1 Bcin06g00620 596 Protease//Early secretome Bctpp2, Secreted protease Bcin06g00630 546 Protease//SignalP-noTM Peptidase S10, serine carboxypeptidase + Peptidase S10, serine carboxypeptidase, active site + Alpha/Beta hydrolase fold + Serine carboxypeptidases, histidine active site Bcin06g00640 497 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin06g00650 487 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin06g00660 360 SignalP-noTM Six-bladed beta-propeller, TolB-like + Major royal jelly protein/Protein yellow Bcin06g00670 528 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin06g00680 812 CAZy : GH55FCW //SignalP-noTM//Early secretome Pectin lyase fold/virulence factor + Pectin lyase fold + Pectate lyase superfamily protein Bcin06g00690 284 SignalP-noTM Bcin06g00700 864 "Bcrsm22, similar to yeast RSM22, Mitochondrial ribosomal protein of the small subunit; also predicted to be an S-adenosylmethionine-dependent methyltransferase [Source:SGD;Acc:S000001638]" Bcin06g00710 490 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin06g00720 353 Bcin06g00730 494 "Bcenp1, similar to yeast ENP1, Protein associated with U3 and U14 snoRNAs; required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus [Source:SGD;Acc:S000000451]" Bcin06g00740 433 Bcdao5, D-amino acid oxidase Bcin06g00750 236 Isochorismatase-like Bcin06g00760 104 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin06g00770 539 Bcin06g00780 613 PIN domain-like Bcin06g00790 524 "Bcprs1, similar to yeast PRS1, 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; plays a key role in cell wall integrity (CWI) pathway; one of five related enzymes, which are active as heteromultimeric complexes; missense mutations in human homolog PRPS1 are associated with neuropathic Arts syndrome and Charcot-Marie Tooth (CMTX5) disease [Source:SGD;Acc:S000001664]" Bcin06g00800 351 Inositol monophosphatase + Inositol monophosphatase, conserved site + Inositol monophosphatase, metal-binding site + Inositol monophosphatase Bcin06g00810 333 Shikimate dehydrogenase substrate binding, N-terminal + NAD(P)-binding domain Bcin06g00820 541 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin06g00830 821 3-dehydroquinate dehydratase type I + Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase + Shikimate dehydrogenase substrate binding, N-terminal + Aldolase-type TIM barrel + NAD(P)-binding domain + P-loop containing nucleoside triphosphate hydrolase + Shikimate kinase/gluconokinase Bcin06g00840 951 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin06g00850 365 Xylose isomerase-like, TIM barrel domain Bcin06g00860 376 Oxidoreductase, N-terminal + Oxidoreductase, C-terminal + NAD(P)-binding domain Bcin06g00870 271 Phospholipase/carboxylesterase/thioesterase + Alpha/Beta hydrolase fold Bcin06g00880 291 Bcin06g00890 523 SignalP-noTM FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin06g00900 409 "Bclip5, similar to yeast LIP5, Protein involved in biosynthesis of the coenzyme lipoic acid; has similarity to E. coli lipoic acid synthase [Source:SGD;Acc:S000005722]" Bcin06g00910 193 DASH complex subunit Spc19 Bcin06g00920 586 "Bcmet1, similar to yeast MET1, S-adenosyl-L-methionine uroporphyrinogen III transmethylase; involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis [Source:SGD;Acc:S000001777]" Bcin06g00930 169 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin06g00940 149 Effector(V2)|Effector(V1) Bcin06g00950 259 Bcin06g00960 869 SignalP-noTM Bcin06g00970 206 Bcin06g00980 753 Heterokaryon incompatibility Bcin06g00990 250 Effector(V2) Bcin06g01000 245 CAZy : GH135 //SignalP-noTM Spherulation-specific family 4 Bcin06g01010 732 Protease//SignalP-noTM Peptidase S8/S53 domain + Proteinase inhibitor, propeptide + Peptidase S53, propeptide + Sedolisin domain Bcin06g01020 447 "Bcipi3, similar to yeast IPI3, Component of the Rix1 complex and pre-replicative complexes (pre-RCs); required for processing of ITS2 sequences from 35S pre-rRNA; component of the pre-60S ribosomal particle with the dynein-related AAA-type ATPase Mdn1p; required for pre-RC formation and maintenance during DNA replication licensing; highly conserved protein which contains several WD40 motifs; IPI3 is an essential gene; other members include Rix1p, Ipi1p, and Ipi3p [Source:SGD;Acc:S000005126]" Bcin06g01030 715 Bcin06g01040 244 Spherulation-specific family 4 Bcin06g01050 570 yes Bzip transcription factor Basic-leucine zipper domain + Protein of unknown function DUF3425 Bcin06g01060 399 Bcin06g01070 415 Putative amidoligase enzyme Bcin06g01080 579 Bcin06g01090 405 Bcin06g01100 113 "Bcmrp2, similar to yeast MRP2, Mitochondrial ribosomal protein of the small subunit [Source:SGD;Acc:S000006370]" Bcin06g01110 883 Bcin06g01120 472 BTB/POZ-like + BTB/POZ fold Bcin06g01130 400 Bcin06g01140 364 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin06g01150 180 Bcin06g01160 286 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin06g01170 432 Bcin06g01180 541 BccatA, Catalase Bcin06g01190 256 BTB/POZ-like + BTB/POZ fold Bcin06g01200 156 Uncharacterised protein family UPF0368, metazoa/fungi + Putative polysaccharide biosynthesis protein + Yst0336-like domain Bcin06g01210 1088 Bcin06g01220 779 Heterokaryon incompatibility Bcin06g01230 883 Forkhead-associated (FHA) domain + SMAD/FHA domain + Nibrin, second BRCT domain Bcin06g01240 411 SignalP-noTM "Bcirc21, similar to yeast IRC21, Putative protein of unknown function; may be involved in resistance to carboplatin and cisplatin; null mutant displays increase in spontaneous Rad52p foci; contains a lipid-binding domain and binds cardiolipin in a large-scale study [Source:SGD;Acc:S000004677]" Bcin06g01250 727 Bcin06g01260 536 Bcin06g01270 162 "Bcmrps8, similar to yeast MRPS8, Mitochondrial ribosomal protein of the small subunit [Source:SGD;Acc:S000004767]" Bcin06g01280 914 SM cluster FluG BcfluG, Glutamine synthetase (GS)-like protein Bcin06g01290 1207 Bcphy3, Phytochrome-like 3, Histidine kinase - group VIII, potential red light sensor Bcin06g01300 631 SignalP-noTM AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain + Long-chain-fatty-acid--CoA ligase FadD17 Bcin06g01310 538 "Bcgpi17, similar to yeast GPI17, Transmembrane protein; subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-S homolog [Source:SGD;Acc:S000002842]" Bcin06g01320 1238 "Bcrtt10, similar to yeast RTT10, WD40 domain-containing protein involved in endosomal recycling; forms a complex with Rrt2p that functions in the retromer-mediated pathway for recycling internalized cell-surface proteins; evidence it interacts with Trm7p for 2'-O-methylation of N34 of substrate tRNAs; has a role in regulation of Ty1 transposition; human ortholog is WDR6 [Source:SGD;Acc:S000006104]" Bcin06g01330 164 Effector(V2)|Effector(V1) Bcin06g01340 331 NmrA-like domain + NAD(P)-binding domain Bcin06g01350 165 Effector(V1) Bcin06g01360 677 "Bciks1, similar to yeast IKS1, Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p [Source:SGD;Acc:S000003593]" Bcin06g01370 883 Protease Peptidase S8/S53 domain + Peptidase S8, subtilisin-related Bcin06g01380 304 Bcin06g01390 910 Cys2His2 transcription factor WD40 repeat + Zinc finger, C2H2-like + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin06g01400 174 Bcin06g01410 177 Bcin06g01420 565 Amidase + Amidase, conserved site + Amidase signature domain Bcin06g01430 204 Effector(V1) Bcin06g01440 597 SignalP-noTM Diphthamide synthesis DHP2, eukaryotic + Diphthamide synthesis DPH1/DPH2 Bcin06g01450 798 Tetratricopeptide-like helical domain + Armadillo-type fold + Clr5 domain Bcin06g01460 1001 Bcin06g01470 50 Effector(V2)|Effector(V1) Bcin06g01480 278 Bcin06g01490 654 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin06g01500 313 Bcin06g01510 404 CAZy : GT17 Glycosyl transferase, family 17 Bcin06g01520 120 Effector(V2)|Effector(V1) Cytochrome c oxidase, subunit VIb Bcin06g01530 495 Anhydro-N-acetylmuramic acid kinase Bcin06g01540 730 SNF2-related + Helicase, C-terminal + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin06g01550 384 Bcin06g01560 521 Bcin06g01570 898 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin06g01580 479 CAZy : GH79 //SignalP-noTM Glycoside hydrolase superfamily + Beta-glucuronidase, C-terminal Bcin06g01590 409 Voltage-dependent anion channel + Malic acid transport protein Bcin06g01600 450 CAZy : GH43,CBM35PCW hemicellulose or pectin//SignalP-noTM Glycoside hydrolase, family 43 + Glycosyl hydrolase, five-bladed beta-propellor domain Bcin06g01610 339 Bcin06g01620 488 Leucine-rich repeat domain, L domain-like Bcin06g01630 539 CAZy : GH79 //SignalP-noTM Glycoside hydrolase superfamily + Beta-glucuronidase, C-terminal Bcin06g01640 530 Succinate semialdehyde dehydrogenase + Aldehyde dehydrogenase domain + Aldehyde dehydrogenase, cysteine active site + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain + Aldehyde dehydrogenase, C-terminal + Aldehyde dehydrogenase, glutamic acid active site Bcin06g01650 203 Effector(V2)|Effector(V1) Bcin06g01660 457 Bcin06g01670 118 Bcin06g01680 315 Protease Phospholipase/carboxylesterase/thioesterase + Alpha/Beta hydrolase fold Bcin06g01690 908 CAZy : GH36PCW hemicellulose Glycosyl hydrolases 36 + Aldolase-type TIM barrel + Glycoside hydrolase superfamily Bcin06g01700 693 "Bcmsy1, similar to yeast MSY1, Mitochondrial tyrosyl-tRNA synthetase [Source:SGD;Acc:S000006018]" Bcin06g01710 531 Pyridoxal phosphate-dependent decarboxylase + Aromatic-L-amino-acid decarboxylase + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase + Pyridoxal-phosphate binding site Bcin06g01720 187 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Bcin06g01730 102 Effector(V2)|Effector(V1) Protein of unknown function DUF427 Bcin06g01740 320 Doublecortin domain + Non-structural maintenance of chromosomes element 1 + Zinc finger, RING-like Bcin06g01750 600 Heterokaryon incompatibility Bcin06g01760 348 SignalP-noTM Bcin06g01770 302 Bcin06g01780 602 SignalP-noTM Bcin06g01790 193 SignalP-noTM Bcin06g01800 259 Bcin06g01810 189 SignalP-noTM//Effector(V2)|Effector(V1) Bcin06g01820 969 CAZy : GH36PCW hemicellulose Glycosyl hydrolases 36 + Aldolase-type TIM barrel + Glycoside hydrolase superfamily Bcin06g01830 750 Flavodoxin + Oxidoreductase FAD/NAD(P)-binding + Flavoprotein pyridine nucleotide cytochrome reductase + FAD-binding, type 1 + Flavodoxin/nitric oxide synthase + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel + NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 + NADPH-dependent diflavin oxidoreductase 1 + Flavoprotein-like Bcin06g01840 358 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin06g01850 373 Arf GTPase activating protein Bcin06g01860 312 Bcin06g01870 673 Heterokaryon incompatibility Bcin06g01880 302 Bcin06g01890 387 Carbohydrate-binding WSC Bcin06g01900 391 Oxoglutarate/iron-dependent dioxygenase + Non-haem dioxygenase N-terminal domain + Isopenicillin N synthase-like Bcin06g01910 531 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin06g01920 741 Annexin repeat Bcin06g01930 817 CAZy : CBM18,CBM18,CBM18,AA5 //SignalP-noTM//Early secretome Bcgo1, Glyoxal oxidase Bcin06g01940 243 Essential protein Yae1, N-terminal Bcin06g01950 190 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Extracellular membrane protein, CFEM domain Bcin06g01960 478 "Bccab1, similar to yeast CAB1, Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase; catalyzes the first committed step in the universal biosynthetic pathway for synthesis of coenzyme A (CoA); transcriptionally regulated by Upc2p via a sterol response element [Source:SGD;Acc:S000002939]" Bcin06g01970 541 Bcin06g01980 1244 GRAM domain + Domain of unknown function DUF4782 Bcin06g01990 564 Bcin06g02000 611 Bcin06g02010 307 Copper chaperone SCO1/SenC + Thioredoxin-like fold Bcin06g02020 514 Protease//SignalP-noTM Bcap11, Aspartic proteinase Bcin06g02030 380 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin06g02040 1936 Bcin06g02050 619 Bcin06g02060 295 Bcin06g02070 371 Bcin06g02080 415 F-box domain + Leucine-rich repeat domain, L domain-like Bcin06g02090 443 Bcin06g02100 252 Ribonucleotide reductase inhibitor Bcin06g02110 469 HAD-superfamily hydrolase, subfamily IIA, CECR5 + HAD-superfamily hydrolase, subfamily IIA + HAD-like domain Bcin06g02120 917 "Bcsec21, similar to yeast SEC21, Gamma subunit of coatomer; coatomer is a heptameric protein complex that together with Arf1p forms the COPI coat; involved in ER to Golgi transport of selective cargo [Source:SGD;Acc:S000005231]" Bcin06g02130 409 CDP-alcohol phosphatidyltransferase + Choline/ethanolamine phosphotransferase Bcin06g02140 413 CAZy : GH28PCW pectin//SignalP-noTM Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin06g02150 84 Bcin06g02160 280 Bzip transcription factor Bcyap3, Bzip transcription factor, Restorer of secondary metabolism A in Aspergillus nidulans Bcin06g02170 117 Bcin06g02180 191 Effector(V2)|Effector(V1) Bcin06g02190 560 Transporter Amino acid/polyamine transporter I Bcin06g02200 370 Bcin06g02210 383 Nucleotide-sugar transporter Bcin06g02220 545 Calcineurin-like phosphoesterase domain, apaH type + Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase + Phosphoprotein phosphatase PPZ + Metallo-dependent phosphatase-like + Serine-threonine protein phosphatase, N-terminal Bcin06g02230 287 Bcin06g02240 346 Actin cortical patch SUR7/pH-response regulator PalI Bcin06g02250 196 Major facilitator superfamily domain Bcin06g02260 296 SignalP-noTM Bcin06g02270 432 Clr5 domain Bcin06g02280 243 Bcin06g02290 159 Effector(V1) Clr5 domain Bcin06g02300 358 "Bclys12, similar to yeast LYS12, Homo-isocitrate dehydrogenase; an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate [Source:SGD;Acc:S000001356]" Bcin06g02310 734 Bcin06g02320 527 Bcin06g02330 521 Bcin06g02340 300 Bcin06g02350 617 "Bcnog2, similar to yeast NOG2, Putative GTPase; associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation [Source:SGD;Acc:S000005336]" Bcin06g02360 2535 "Bcfab1, similar to yeast FAB1, 1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis [Source:SGD;Acc:S000001915]" Bcin06g02370 1367 Bcin06g02380 293 yes Bcer, UDP-4-keto-6-deoxyglucose-3,5-epimerase/-4-reductase Bcin06g02390 504 DnaJ domain + DnaJ domain, conserved site + DNAJ-containing protein, X-domain Bcin06g02400 482 "Bcerg9, similar to yeast ERG9, Farnesyl-diphosphate farnesyl transferase (squalene synthase); joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway [Source:SGD;Acc:S000001233]" Bcin06g02410 332 Triose-phosphate transporter domain Bcin06g02420 1083 Transporter//SignalP-noTM "Bcadp1, similar to yeast ADP1, Putative ATP-dependent permease of the ABC transporter family [Source:SGD;Acc:S000000604]" Bcin06g02430 396 Aminotransferases, class-I, pyridoxal-phosphate-binding site + Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin06g02440 168 Effector(V2) Bcin06g02450 585 Heterokaryon incompatibility Bcin06g02460 245 Bcgst4, Glutathione S-transferase Bcin06g02470 359 SET domain Bcin06g02480 222 Effector(V2) Bcin06g02490 65 Effector(V1) Proteolipid membrane potential modulator Bcin06g02500 497 Calcium/proton exchanger CAX + Sodium/calcium exchanger membrane region Bcin06g02510 553 Protease//SignalP-noTM//Early secretome Peptidase S10, serine carboxypeptidase + Peptidase S10, serine carboxypeptidase, active site + Alpha/Beta hydrolase fold + Serine carboxypeptidases, histidine active site Bcin06g02520 553 Alpha/Beta hydrolase fold Bcin06g02530 645 Domain of unknown function DUF2235 Bcin06g02540 168 RPEL repeat Bcin06g02550 637 DNA-repair protein, UmuC-like + DNA polymerase, Y-family, little finger domain + DNA polymerase IV Bcin06g02560 804 "Bcmef1, similar to yeast MEF1, Mitochondrial elongation factor involved in translational elongation [Source:SGD;Acc:S000004059]" Bcin06g02570 308 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin06g02580 271 Protein of unknown function DUF3425 Bcin06g02590 527 Bcin06g02600 309 Prenyltransferase-like Bcin06g02610 493 "Bcrpn5, similar to yeast RPN5, Subunit of the CSN and 26S proteasome lid complexes; similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p; Rpn5p is an essential protein; the COP9 signalosome is also known as the CSN [Source:SGD;Acc:S000002306]" Bcin06g02620 284 Serine hydrolase FSH + Alpha/Beta hydrolase fold Bcin06g02630 247 Bcin06g02640 911 EGF-like, conserved site Bcin06g02650 71 Effector(V1) Bcin06g02660 127 Effector(V2)|Effector(V1) Bcin06g02670 505 Cytochrome P450 + Cytochrome P450, E-class, CYP52 Bcin06g02680 268 Protein of unknown function DUF3328 Bcin06g02690 92 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin06g02700 996 Dynamin superfamily + P-loop containing nucleoside triphosphate hydrolase Bcin06g02710 219 Bcin06g02720 181 Effector(V1) DNA/RNA-binding protein Alba-like + Ribonuclease P/MRP, subunit p20 + Ribonuclease P/MRP, subunit POP7 Bcin06g02730 300 RAVE subunit 2/Rogdi Bcin06g02740 188 Effector(V1) AMP-dependent synthetase/ligase Bcin06g02750 461 Aminotransferase class V domain + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase Bcin06g02760 342 Dimeric alpha-beta barrel + NIPSNAP Bcin06g02770 61 Effector(V2)|Effector(V1) ATPase, F0 complex, subunit J Bcin06g02780 985 Bcin06g02790 405 Bcin06g02800 191 Bcin06g02810 230 Bcin06g02820 571 "Bcdps1, similar to yeast DPS1, Aspartyl-tRNA synthetase, primarily cytoplasmic; homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation; shares five highly conserved amino acids with human that when mutated cause leukoencephalopathy characterized by hypomyelination with brain stem and spinal cord involvement and leg spasticity (HBSL) [Source:SGD;Acc:S000003941]" Bcin06g02830 441 "Bcspe1, similar to yeast SPE1, Ornithine decarboxylase; catalyzes the first step in polyamine biosynthesis; degraded in a proteasome-dependent manner in the presence of excess polyamines; deletion decreases lifespan, and increases necrotic cell death and ROS generation [Source:SGD;Acc:S000001667]" Bcin06g02840 550 Bcin06g02850 1471 "Bckog1, similar to yeast KOG1, Subunit of TORC1; TORC1 is a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors [Source:SGD;Acc:S000001229]" Bcin06g02860 1604 Kelch repeat type 1 + Kelch-type beta propeller Bcin06g02870 368 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin06g02880 217 Effector(V1) Bcin06g02890 82 Effector(V2)|Effector(V1) Ribosomal protein S27e + Zinc-binding ribosomal protein + Ribosomal protein S27e, zinc-binding domain Bcin06g02900 257 PhLP2, Phosducin-like protein (subgroup II) Bcin06g02910 175 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin06g02920 167 "Bcpex4, similar to yeast PEX4, Peroxisomal ubiquitin conjugating enzyme; required for peroxisomal matrix protein import and peroxisome biogenesis [Source:SGD;Acc:S000003365]" Bcin06g02930 856 Bcin06g02940 849 Bcin06g02950 316 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain + Friend of PRMT1 duplication Bcin06g02960 343 6-phosphogluconate dehydrogenase, NADP-binding + 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal + NAD(P)-binding domain Bcin06g02970 1626 SignalP-noTM Bcin06g02980 847 Protease//SignalP-noTM Aspartic peptidase + Aspartic peptidase domain + Peptidase family A1 domain Bcin06g02990 195 Bcin06g03000 138 Bcin06g03010 267 Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin06g03020 376 Bcin06g03030 196 Effector(V2) Bcin06g03040 604 Bcin06g03050 317 Bcin06g03060 232 Effector(V2) Bcgst9, Glutathione S-transferase Bcin06g03070 686 Protease//SignalP-noTM Peptidase S8/S53 domain + Proteinase inhibitor, propeptide + Peptidase S53, propeptide + Sedolisin domain Bcin06g03080 446 "Bchst2, similar to yeast HST2, Cytoplasmic NAD(+)-dependent protein deacetylase; member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro; contains a nuclear export signal (NES); function regulated by its nuclear export [Source:SGD;Acc:S000005936]" Bcin06g03090 600 Bcin06g03100 487 Effector(V1) Bcin06g03110 473 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin06g03120 147 Effector(V1) Bcin06g03130 642 Aminotransferase class V domain + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin06g03140 228 SignalP-noTM//Effector(V2)|Effector(V1) Bcin06g03150 88 Effector(V1) Ribonuclease kappa Bcin06g03160 254 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcsod2, Cu/Zn superoxide dismutase Bcin06g03170 551 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin06g03180 1213 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger, C2H2-like Bcin06g03190 431 "Bcrrd2, similar to yeast RRD2, Peptidyl-prolyl cis/trans-isomerase; also activates the phosphotyrosyl phosphatase activity of protein phosphatase 2A (PP2A); regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006073]" Bcin06g03200 256 "Bcrrp46, similar to yeast RRP46, Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp46p (EXOSC5) [Source:SGD;Acc:S000003327]" Bcin06g03210 643 NAD kinase + NAD kinase/diacylglycerol kinase-like domain + ATP-NAD kinase, PpnK-type, all-beta + Inorganic polyphosphate/ATP-NAD kinase, domain 1 Bcin06g03220 374 CAZy : GT62 "Bcmnn9, similar to yeast MNN9, Subunit of Golgi mannosyltransferase complex; this complex mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation; this complex also contains Anp1p, Mnn10p, Mnn11p, and Hoc1p [Source:SGD;Acc:S000005971]" Bcin06g03230 352 Bcin06g03240 556 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin06g03250 174 Effector(V1) Marvel domain Bcin06g03260 755 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin06g03270 150 SignalP-noTM//Effector(V2)|Effector(V1)//Early secretome Cyanovirin-N Bcin06g03280 950 "Bcprp22, similar to yeast PRP22, DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase; associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes; required for proofreading the exon ligation reaction [Source:SGD;Acc:S000000815]" Bcin06g03290 542 "Bcpwp1, similar to yeast PWP1, Protein with WD-40 repeats involved in rRNA processing; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily [Source:SGD;Acc:S000004186]" Bcin06g03300 262 Bcin06g03310 364 Bromo adjacent homology (BAH) domain Bcin06g03320 124 Effector(V2)|Effector(V1) Protein of unknown function DUF3602 Bcin06g03330 233 Bcin06g03340 760 Bcin06g03350 215 Ribosomal protein L13e + Ribosomal protein L13, eukaryotic Bcin06g03360 177 Effector(V2)|Effector(V1) Bcin06g03370 393 "Bcpic2, similar to yeast PIC2, Mitochondrial copper and phosphate carrier; imports copper and inorganic phosphate into mitochondria; functionally redundant with Mir1p but less abundant than Mir1p under normal conditions; expression is induced at high temperature [Source:SGD;Acc:S000000855]" Bcin06g03380 510 FAD linked oxidase, N-terminal + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin06g03390 247 Effector(V2)|Effector(V1) NAD(P)-binding domain Bcin06g03400 291 "Bcpef1, similar to yeast PEF1, Penta-EF-hand protein; required for polar bud growth and cell wall abscission; binds calcium and zinc with different affinity; localizes to bud site in G1, bud neck in G2; binds to Sec31p and modulates COPII coat assembly [Source:SGD;Acc:S000003290]" Bcin06g03410 252 "Bcgcg1, similar to yeast GCG1, Gamma-glutamyl cyclotransferase; cleaves the gamma-glutamyl bond of glutathione to yield 5-oxoproline and a Cys-Gly dipeptide; similar to mammalian pro-apoptotic protein ChaC1; expression of mouse ChaC1 in yeast increases apoptosis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; periodically expressed during the metabolic cycle [Source:SGD;Acc:S000000965]" Bcin06g03420 188 Effector(V1) RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin06g03430 1029 SignalP-noTM Bcin06g03440 361 yes Bcaox, Mitochondrial alternative oxydase Bcin06g03450 867 "Bcmef2, similar to yeast MEF2, Mitochondrial elongation factor involved in translational elongation [Source:SGD;Acc:S000003638]" Bcin06g03460 606 "Bcvps17, similar to yeast VPS17, Subunit of the membrane-associated retromer complex; essential for endosome-to-Golgi retrograde protein transport; peripheral membrane protein that assembles onto the membrane with Vps5p to promote vesicle formation; required for recruiting the retromer complex to the endosome membranes [Source:SGD;Acc:S000005658]" Bcin06g03470 431 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin06g03480 407 JAB1/MPN/MOV34 metalloenzyme domain + Rpn11/EIF3F C-terminal domain + COP9 signalosome subunit 6 Bcin06g03490 632 Bcin06g03500 678 CAZy : GH125 Uncharacterised conserved protein UCP028846 + Six-hairpin glycosidase-like + Six-hairpin glycosidase Bcin06g03510 649 Bzip transcription factor//Effector(V2)|Effector(V1) Basic-leucine zipper domain Bcin06g03520 134 Effector(V2)|Effector(V1) Bcin06g03530 427 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin06g03540 281 SignalP-noTM Bcin06g03550 466 "Bcgpi2, similar to yeast GPI2, Protein involved in the synthesis of GlcNAc-PI; GlcNAc-PI is the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein; GlcNAc-PI stands for N-acetylglucosaminyl phosphatidylinositol [Source:SGD;Acc:S000005997]" Bcin06g03560 410 Zinc finger, MYND-type Bcin06g03570 488 Zinc finger, MYND-type Bcin06g03580 226 Effector(V2)|Effector(V1) Bcin06g03590 152 Effector(V1) Bcin06g03600 195 Effector(V2)|Effector(V1) GNAT domain + Acyl-CoA N-acyltransferase Bcin06g03610 798 Oligopeptide transporter, OPT superfamily Bcin06g03620 371 Bcin06g03630 666 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin06g03640 548 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin06g03650 390 Bcin06g03660 455 CAZy : GH76FCW Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase + Mannan endo-1,6-alpha-mannosidase Bcin06g03670 505 Bcin06g03680 140 Effector(V1) Bcin06g03690 258 Effector(V2) Bcin06g03700 403 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin06g03710 701 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin06g03720 440 Major facilitator superfamily + Major facilitator superfamily domain Bcin06g03730 89 SignalP-noTM Bcin06g03740 131 SignalP-noTM Bcin06g03750 195 Bcin06g03760 272 Protein of unknown function DUF3431 Bcin06g03770 782 SignalP-noTM Bcin06g03780 442 Bcin06g03790 558 CAZy : GT2 Glycosyltransferase 2-like + Nucleotide-diphospho-sugar transferases Bcin06g03800 1034 CAZy : GHnc //SignalP-noTM Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin06g03810 341 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin06g03820 481 yes Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin06g03830 368 BTB/POZ-like + BTB/POZ fold Bcin06g03840 185 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Bcin06g03850 324 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin06g03860 329 Bcin06g03870 284 Bcin06g03880 709 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin06g03890 401 Six-bladed beta-propeller, TolB-like Bcin06g03900 124 Effector(V2)|Effector(V1) Bcin06g03910 691 Ysc84 actin-binding domain Bcin06g03920 399 CAZy : CE16PCW hemicellulose//SignalP-noTM SGNH hydrolase-type esterase domain Bcin06g03930 184 Effector(V1) Bcin06g03940 355 Bcin06g03950 80 Effector(V2)|Effector(V1) At2g23090 like Bcin06g03960 570 SignalP-noTM Bcin06g03970 596 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin06g03980 435 "Bchem15, similar to yeast HEM15, Ferrochelatase; a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway [Source:SGD;Acc:S000005702]" Bcin06g03990 649 yes Bcku70, Protein involved in DNA reparation Bcin06g04000 2437 "Bctho2, similar to yeast THO2, Subunit of the THO complex; THO is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids [Source:SGD;Acc:S000005083]" Bcin06g04010 512 Protease "Bcmet2, similar to yeast MET2, L-homoserine-O-acetyltransferase; catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway [Source:SGD;Acc:S000005221]" Bcin06g04020 482 Ergosterol biosynthesis ERG4/ERG24 + Sterol reductase, conserved site Bcin06g04030 332 Bcin06g04040 266 Bcin06g04050 442 Lipopolysaccharide-modifying protein Bcin06g04060 411 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin06g04070 360 Organic solute transporter subunit alpha/Transmembrane protein 184 Bcin06g04080 542 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin06g04090 562 Bcin06g04100 354 4'-phosphopantetheinyl transferase superfamily Bcin06g04110 606 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin06g04120 442 Acyl-CoA oxidase/dehydrogenase, central domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase/oxidase, N-terminal Bcin06g04130 368 Bcin06g04140 524 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin06g04150 261 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin06g04160 290 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin06g04170 589 Heterokaryon incompatibility Bcin06g04180 266 Dimeric alpha-beta barrel Bcin06g04190 220 Bcin06g04200 282 Bcin06g04210 350 Bcin06g04220 182 Bcin06g04230 433 Protease Peptidase M20 + Peptidase M20, dimerisation domain + Amidohydrolase Bcin06g04240 578 Leucine-rich repeat domain, L domain-like Bcin06g04250 170 Effector(V1) Bcin06g04260 642 Bcin06g04270 254 Effector(V2) Bcin06g04280 807 Zn2/Cys6 + fungal trans transcription factor//Effector(V2)|Effector(V1) Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin06g04290 241 CAZy : CE5PCW hemicellulose//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Cutinase + Alpha/Beta hydrolase fold Bcin06g04300 232 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain + FMN-binding split barrel Bcin06g04310 360 "Bclip2, similar to yeast LIP2, Lipoyl ligase; involved in the modification of mitochondrial enzymes by the attachment of lipoic acid groups [Source:SGD;Acc:S000004229]" Bcin06g04320 278 Actin cortical patch SUR7/pH-response regulator PalI Bcin06g04330 752 Protease Ovarian tumour, otubain + Peptidase C65, otubain Bcin06g04340 144 Bcin06g04350 73 Effector(V2) Bcin06g04360 500 Proteasome component (PCI) domain + Tetratricopeptide-like helical domain + Winged helix-turn-helix DNA-binding domain Bcin06g04370 468 "Bccwc25, similar to yeast CWC25, Splicing factor required for the first step of pre-mRNA splicing; binding to the spliceosome requires Prp2p and Yju2p; heat-stable protein; has similarity to S. pombe Cwf25p [Source:SGD;Acc:S000005189]" Bcin06g04380 145 Effector(V2)|Effector(V1) Bcin06g04390 209 yes Effector(V1)//Signaling pathway Bcrho3, Small GTPase Bcin06g04400 615 Major intrinsic protein + Aquaporin-like Bcin06g04410 1213 AMP-dependent synthetase/ligase + Acyl carrier protein-like + AMP-binding, conserved site Bcin06g04420 514 Cytochrome P450 + Cytochrome P450, E-class, group II + Cytochrome P450, E-class, CYP52 + Cytochrome P450, conserved site Bcin06g04430 592 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain Bcin06g04440 161 Effector(V1) Bcin06g04450 181 Effector(V1) Bcin06g04460 303 Intradiol ring-cleavage dioxygenase, C-terminal + Catechol dioxygenase, N-terminal + Intradiol ring-cleavage dioxygenase, core Bcin06g04470 377 WD40/YVTN repeat-like-containing domain + Lactonase, 7-bladed beta propeller Bcin06g04480 555 Protease Alpha/beta hydrolase fold-1 + Dimeric alpha-beta barrel + Alpha/Beta hydrolase fold Bcin06g04490 1398 Bckmt6, Histone H3 K27 Methyltransferase Bcin06g04500 1007 CAZy : GH35PCW hemicellulose//SignalP-noTM//Early secretome Glycoside hydrolase, family 35 + Galactose-binding domain-like + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Beta-galactosidase, domain 2 + Beta-galactosidase jelly roll domain + Beta-galactosidase, domain 3 + Glycoside hydrolase 35, catalytic domain Bcin06g04510 435 Bcin06g04520 737 Bccat3, Catalase Bcin06g04530 331 GroES (chaperonin 10)-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin06g04540 386 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin06g04550 396 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin06g04560 592 CAZy : GH47 Glycoside hydrolase, family 47 Bcin06g04570 274 Bcin06g04580 412 Transporter General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin06g04590 344 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin06g04600 137 Effector(V2) YjgF/Yer057p/UK114 family + Endoribonuclease L-PSP/chorismate mutase-like Bcin06g04610 690 Zn2/Cys6 transcription factor//Effector(V2)|Effector(V1) Zn(2)-C6 fungal-type DNA-binding domain Bcin06g04620 264 F-box domain Bcin06g04630 323 "Bcsed5, similar to yeast SED5, cis-Golgi t-SNARE syntaxin; required for vesicular transport between the ER and the Golgi complex; binds at least 9 SNARE proteins [Source:SGD;Acc:S000004016]" Bcin06g04640 2462 Bcin06g04650 223 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin06g04660 310 yes Bcgar1, Galacturonate reductase Bcin06g04670 283 Bcin06g04680 836 Protein of unknown function DUF3433 Bcin06g04690 963 Bcin06g04700 495 Transporter "Bcgit1, similar to yeast GIT1, Plasma membrane permease; mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability [Source:SGD;Acc:S000000695]" Bcin06g04710 738 Cys2His2 transcription factor G-patch domain + RNA recognition motif domain + Zinc finger, RanBP2-type + Zinc finger, C2H2 + Nucleotide-binding alpha-beta plait domain + RED-like, N-terminal Bcin06g04720 194 Effector(V1) Molybdopterin biosynthesis MoaE + Molybdopterin synthase catalytic subunit, eukaryotes Bcin06g04730 292 Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin06g04740 261 Oxoglutarate/iron-dependent dioxygenase + Prolyl 4-hydroxylase, alpha subunit Bcin06g04750 359 SignalP-noTM Bcin06g04760 74 Bcin06g04770 283 SignalP-noTM Concanavalin A-like lectin/glucanase domain Bcin06g04780 301 Bcin06g04790 273 Bcin06g04800 392 Bcin06g04810 578 Zinc finger, CCCH-type + SH3 domain Bcin06g04820 319 CAZy : CE1PCW hemicellulose//Protease//Effector(V2)|Effector(V1)//Early secretome Alpha/Beta hydrolase fold Bcin06g04830 417 CAZy : GH5PCW/FCW //SignalP-noTM Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin06g04840 777 CAZy : GH3PCW/FCW //Early secretome Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Fibronectin type III-like domain Bcin06g04850 766 CAZy : GH31PCW hemicellulose Glycoside hydrolase family 31 + Galactose mutarotase-like domain + Aldolase-type TIM barrel + Glycoside hydrolase superfamily + Glycoside hydrolase family 31, N-terminal domain Bcin06g04860 501 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin06g04870 454 Signaling pathway Bcgpr3, G protein-coupled receptor 3 Bcin06g04880 1062 "Bcopt1, similar to yeast OPT1, Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family [Source:SGD;Acc:S000003748]" Bcin06g04890 234 Effector(V2)|Effector(V1) Bcin06g04900 297 Inositol monophosphatase + Inositol monophosphatase, conserved site + Inositol monophosphatase Bcin06g04910 361 SignalP-noTM Bcin06g04920 341 Bcin06g04930 155 Effector(V1) Bcin06g04940 308 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin06g04950 539 Calcium/proton exchanger CAX + Sodium/calcium exchanger membrane region Bcin06g04960 571 AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain Bcin06g04970 698 Zinc finger, RING-type + Zinc finger, C6HC-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site + E3 ubiquitin ligase RBR family Bcin06g04980 461 "Bccab2, similar to yeast CAB2, Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC); subunits of this complex are: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p; probable phosphopantothenoylcysteine synthetase (PPCS), which catalyzes the second step of coenzyme A biosynthesis from pantothenate; null mutant lethality is complemented by E. coli coaBC (encoding a bifunctional enzyme with PPCS activity) [Source:SGD;Acc:S000001345]" Bcin06g04990 671 Major facilitator superfamily domain + Acetyl-coenzyme A transporter 1 Bcin06g05000 320 Centromere protein O Bcin06g05010 290 Effector(V2) Bcin06g05020 109 Bcin06g05030 1574 "Bcvip1, similar to yeast VIP1, Inositol hexakisphosphate and inositol heptakisphosphate kinase; inositol heptakisphosphate (IP7) production is important for phosphate signaling; involved in cortical actin cytoskeleton function, and invasive pseudohyphal growth analogous to S. pombe asp1; inositol hexakisphosphate is also known as IP6 [Source:SGD;Acc:S000004402]" Bcin06g05040 1039 "Bcutp21, similar to yeast UTP21, Subunit of U3-containing 90S preribosome and SSU processome complexes; involved in production of 18S rRNA and assembly of small ribosomal subunit; synthetic defect with STI1 Hsp90 cochaperone; human homolog linked to glaucoma; Small Subunit processome is also known as SSU processome [Source:SGD;Acc:S000004401]" Bcin06g05050 403 CAZy : AA13,CBM20 //SignalP-noTM//Early secretome Carbohydrate binding module family 20 + Chitin-binding, domain 3 + Immunoglobulin-like fold + Carbohydrate-binding-like fold Bcin06g05060 56 Effector(V2)|Effector(V1) Bcin06g05070 227 SignalP-noTM Bcin06g05080 1067 SignalP-noTM Galactose oxidase/kelch, beta-propeller Bcin06g05090 262 SignalP-noTM//Effector(V1) Dimeric alpha-beta barrel Bcin06g05100 495 Bcin06g05110 347 Pirin, N-terminal domain + RmlC-like cupin domain + RmlC-like jelly roll fold Bcin06g05120 460 SignalP-noTM Bcin06g05130 228 Mediator complex, subunit Med8, fungi/metazoa + Mediator complex, subunit Med8, fungi Bcin06g05140 297 PQ-loop repeat + Mannose-P-dolichol utilization defect 1 protein Bcin06g05150 438 Major facilitator superfamily + Major facilitator superfamily domain Bcin06g05160 593 Fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin06g05170 568 Amidase + Amidase signature domain + Amidase, conserved site Bcin06g05180 490 Armadillo-type fold + Guanine nucleotide exchange factor, Ric8 Bcin06g05190 416 CAZy : GH64FCW Beta-1,3-glucanase, N-terminal Bcin06g05200 530 SignalP-noTM//Early secretome Histidine phosphatase superfamily, clade-2 + Histidine phosphatase superfamily Bcin06g05210 421 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin06g05220 378 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain Bcin06g05230 465 yes Zn2/Cys6 transcription factor BcSpd1, Zn2/Cys6 transcription factor Bcin06g05240 601 Organic solute transporter subunit alpha/Transmembrane protein 184 Bcin06g05250 417 Putative amidoligase enzyme Bcin06g05260 1217 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB Bcin06g05270 520 CAZy : GT71 Alpha-mannosyltransferase + Nucleotide-diphospho-sugar transferases Bcin06g05280 176 Bcin06g05290 504 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin06g05300 1134 "Bcmsh3, similar to yeast MSH3, Mismatch repair protein; forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability [Source:SGD;Acc:S000000688]" Bcin06g05310 591 Bcin06g05320 338 "Bcbet2, similar to yeast BET2, Beta subunit of Type II geranylgeranyltransferase; required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p [Source:SGD;Acc:S000006380]" Bcin06g05330 261 Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin06g05340 342 Butirosin biosynthesis, BtrG-like + Gamma-glutamylcyclotransferase Bcin06g05350 277 S-adenosyl-L-methionine-dependent methyltransferase Bcin06g05360 321 DapA-like + Aldolase-type TIM barrel Bcin06g05370 323 SignalP-noTM Bcin06g05380 929 Kinesin motor domain + Kinesin motor domain, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin06g05390 152 Effector(V2)|Effector(V1) Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like + Ubiquitin-conjugating enzyme, active site Bcin06g05400 434 Thiolase + Thiolase-like + Thiolase, active site + Thiolase, acyl-enzyme intermediate active site + Thiolase, N-terminal + Thiolase, C-terminal Bcin06g05410 243 Bcin06g05420 173 Effector(V2)|Effector(V1) Bcin06g05430 1047 Zn2/Cys6 + fungal trans transcription factor BcuaY, Zn2/Cys6 transcription factor Bcin06g05440 578 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin06g05450 226 Effector(V1) Coiled-coil domain-containing protein 124/Lso1/Lso2 Bcin06g05460 308 Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like Bcin06g05470 741 Bcin06g05480 306 Bcin06g05490 257 SNF2-related + P-loop containing nucleoside triphosphate hydrolase Bcin06g05500 155 Effector(V1) Bcin06g05510 708 G-patch domain + Domain of unknown function DUF1604 Bcin06g05520 1052 Protein kinase domain + Kinase associated domain 1 (KA1) + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site + KA1 domain/Ssp2 C-terminal domain Bcin06g05530 521 CAZy : GT15 "Bcktr6, similar to yeast KTR6, Probable mannosylphosphate transferase; involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2/MNT1 mannosyltransferase family; KTR6 has a paralog, KRE2, that arose from the whole genome duplication [Source:SGD;Acc:S000005974]" Bcin06g05540 131 SignalP-noTM//Effector(V1) Bcin06g05550 422 Ankyrin repeat + Ankyrin repeat-containing domain Bcin06g05560 109 Effector(V2)|Effector(V1) Bcin06g05570 230 Effector(V2) Protein of unknown function DUF1772 Bcin06g05580 408 Bcin06g05590 662 Ribonucleotide reductase, transcriptional regulator CRT10 Bcin06g05600 2376 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin06g05610 88 Bcin06g05620 577 Bcin06g05630 473 NADH-quinone oxidoreductase, subunit D + NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site + NAD(P)H-quinone oxidoreductase subunit D/H + NiFe hydrogenase-like Bcin06g05640 389 "Bcrpc40, similar to yeast RPC40, RNA polymerase subunit AC40; common to RNA polymerase I and III [Source:SGD;Acc:S000006314]" Bcin06g05650 439 UBA/THIF-type NAD/FAD binding fold + E2 binding + NAD(P)-binding domain + Ubiquitin activating enzyme, alpha domain + NEDD8-activating enzyme E1 catalytic subunit Bcin06g05660 999 Telomere length regulation protein, conserved domain Bcin06g05670 447 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin06g05680 475 Protease WLM Bcin06g05690 487 Protease Alpha/beta hydrolase fold-1 + Peptidase S33 + Alpha/Beta hydrolase fold Bcin06g05700 695 Kelch-type beta propeller + Domain of unknown function DUF4110 Bcin06g05710 315 Early secretome Zinc finger, HIT-type Bcin06g05720 114 Effector(V2)|Effector(V1) Bcin06g05730 531 yes SignalP-noTM//Early secretome Bcpdi1, Protein disulfide-isomerase Bcin06g05740 1153 Bcin06g05750 315 Bcin06g05760 686 "Bcmon1, similar to yeast MON1, Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; role in localizing Ypt7p to the vacuolar membrane; required for autophagy, the CVT pathway and mitophagy; potential Cdc28 substrate [Source:SGD;Acc:S000003092]" Bcin06g05770 1890 "Bcdop1, similar to yeast DOP1, Golgi-localized, leucine-zipper domain containing protein; involved in endosome to Golgi transport, organization of the ER, establishing cell polarity, and morphogenesis; detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000002548]" Bcin06g05780 478 Peptidase A2A, retrovirus, catalytic Bcin06g05790 340 Bcin06g05800 404 Cys2His2 transcription factor Bcltf15, Light-responsive Cys2His2 transcription factor Bcin06g05810 583 RNA recognition motif domain + RNA recognition motif domain, eukaryote + U2 snRNP auxilliary factor, large subunit, splicing factor + Nucleotide-binding alpha-beta plait domain Bcin06g05820 424 "Bcogg1, similar to yeast OGG1, Nuclear and mitochondrial glycosylase/lyase; specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA, contributes to UVA resistance [Source:SGD;Acc:S000004525]" Bcin06g05830 263 "Bclcl3, similar to yeast LCL3, Putative protein of unknown function; mutant has long chronological lifespan; has homology to Staphylococcus aureus nuclease; GFP-fusion protein localizes to mitochondria; is induced in response to the DNA-damaging agent MMS [Source:SGD;Acc:S000003053]" Bcin06g05840 1241 SignalP-noTM "Bcrax2, similar to yeast RAX2, N-glycosylated protein; involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p; RAX2 mRNA stability is regulated by Mpt5p [Source:SGD;Acc:S000004074]" Bcin06g05850 494 GPCR, family 2, secretin-like + GPCR, family 2-like Bcin06g05860 151 Effector(V1) "Bcrps13, similar to yeast RPS13, Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S13 and bacterial S15 [Source:SGD;Acc:S000002471]" Bcin06g05870 205 Dpy-30 motif Bcin06g05880 933 VRR-NUC domain + Fanconi-associated nuclease 1-like Bcin06g05890 825 Sulphate anion transporter + STAS domain + Sulphate transporter + Sulphate anion transporter, conserved site Bcin06g05900 453 "Bcbub2, similar to yeast BUB2, Mitotic exit network regulator; forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage [Source:SGD;Acc:S000004659]" Bcin06g05910 243 Dimeric alpha-beta barrel Bcin06g05920 488 K Homology domain + K Homology domain, type 1 Bcin06g05930 338 Bcin06g05940 831 "Bcdsf2, similar to yeast DSF2, Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000211]" Bcin06g05950 439 "Bcerv46, similar to yeast ERV46, Protein localized to COPII-coated vesicles; forms a complex with Erv41p; involved in the membrane fusion stage of transport [Source:SGD;Acc:S000000040]" Bcin06g05960 666 "Bcmex67, similar to yeast MEX67, Poly(A)RNA binding protein involved in nuclear mRNA export; component of the nuclear pore; ortholog of human TAP [Source:SGD;Acc:S000006090]" Bcin06g05970 568 CAZy : GH47 Glycoside hydrolase, family 47 Bcin06g05980 314 SignalP-noTM//Effector(V1) Protein of unknown function DUF3129 Bcin06g05990 481 Luciferase-like domain + Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A Bcin06g06000 621 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin06g06010 466 Major facilitator superfamily + Major facilitator superfamily domain Bcin06g06020 1459 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase + Alpha-factor-transporting ATPase Ste6 Bcin06g06030 393 Domain of unknown function DUF202 Bcin06g06040 471 yes CAZy : GH132 //SignalP-noTM//Early secretome Bcsun1, Small secreted SUN-family glycoprotein Bcin06g06050 378 Bcin06g06060 205 Bcin06g06070 568 Transporter Amino acid/polyamine transporter I + Amino acid permease/ SLC12A domain Bcin06g06080 1566 TRAPP II complex, TRAPPC10 Bcin06g06090 351 SignalP-noTM//Early secretome Six-bladed beta-propeller, TolB-like Bcin06g06100 111 Effector(V2)|Effector(V1) Bcin06g06110 179 Effector(V1) Protein of unknown function DUF2205, coiled-coil Bcin06g06120 512 Bcin06g06130 162 Effector(V2)|Effector(V1) NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8 Bcin06g06140 1607 "Bcswr1, similar to yeast SWR1, Swi2/Snf2-related ATPase; structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; relocalizes to the cytosol in response to hypoxia; chronological aging factor that mediates lifespan extension by dietary restriction [Source:SGD;Acc:S000002742]" Bcin06g06150 342 Wax synthase domain Bcin06g06160 173 NUDIX hydrolase domain + NUDIX hydrolase domain-like + NUDIX hydrolase, conserved site + NUDIX hydrolase Bcin06g06170 461 MmgE/PrpD Bcin06g06180 517 Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin06g06190 149 "Bcpkr1, similar to yeast PKR1, V-ATPase assembly factor; functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0); protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004730]" Bcin06g06200 137 Effector(V1) "Bcsmd1, similar to yeast SMD1, Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; relocalizes to the cytosol in response to hypoxia; homolog of human Sm D1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003306]" Bcin06g06210 261 "Bcmtq2, similar to yeast MTQ2, S-adenosylmethionine-dependent methyltransferase; subunit of complex with Trm112p that methylates translation release factor Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; similar to E.coli PrmC; member of the seven beta-strand family [Source:SGD;Acc:S000002547]" Bcin06g06220 139 "Bcsdh7, similar to yeast SDH7, Mitochondrial protein involved in assembly of succinate dehydrogenase; has a role in maturation of the Sdh2p subunit; localized to the mitochondrial intermembrane space; required for acetate utilization and gluconeogenesis; mutation in Drosophila ortholog SDHAF3 causes reduced succinate dehydrogenase activity and neuronal and muscular dysfunction; member of the LYR protein family [Source:SGD;Acc:S000002919]" Bcin06g06230 106 Effector(V2)|Effector(V1) Bcin06g06240 402 Taurine catabolism dioxygenase TauD/TfdA Bcin06g06250 805 Zn2/Cys6 + fungal trans transcription factor//Signaling pathway Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin06g06260 274 Protease//Effector(V2) "Bcpup1, similar to yeast PUP1, Beta 2 subunit of the 20S proteasome; endopeptidase with trypsin-like activity that cleaves after basic residues; synthesized as a proprotein before being proteolytically processed for assembly into 20S particle; human homolog is subunit Z [Source:SGD;Acc:S000005683]" Bcin06g06270 1512 "Bcnup159, similar to yeast NUP159, FG-nucleoporin component of central core of the nuclear pore complex; also part of the nuclear pore complex (NPC) cytoplasmic filaments; contributes directly to nucleocytoplasmic transport; regulates ADP release from the ATP-dependent RNA helicase Dbp5p; forms a stable association with Nup82p, Gle2p and two other FG-nucleoporins (Nsp1p and Nup116p) [Source:SGD;Acc:S000001377]" Bcin06g06280 419 Heat shock protein DnaJ, cysteine-rich domain + DnaJ domain + Chaperone DnaJ, C-terminal + HSP40/DnaJ peptide-binding + Chaperone DnaJ + DnaJ domain, conserved site Bcin06g06290 159 Effector(V2)|Effector(V1) "Bcfcy1, similar to yeast FCY1, Cytosine deaminase; zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU) [Source:SGD;Acc:S000006266]" Bcin06g06300 364 "Bchem12, similar to yeast HEM12, Uroporphyrinogen decarboxylase; catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; a hem12 mutant has phenotypes similar to patients with porphyria cutanea tarda [Source:SGD;Acc:S000002454]" Bcin06g06310 801 Bcin06g06320 518 "Bctrm82, similar to yeast TRM82, Catalytic subunit of a tRNA methyltransferase complex; Trm8p and Trm82p comprise an enzyme that catalyzes a methyl-transfer from S-adenosyl-l-methionine to the N(7) atom of guanine at position 46 in tRNA; Trm8 lacks catalytic activity if not bound to Trm82p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002572]" Bcin06g06330 312 "Bcrpp0, similar to yeast RPP0, Conserved ribosomal protein P0 of the ribosomal stalk; involved in interaction between translational elongation factors and the ribosome; phosphorylated on serine 302; homologous to mammalian ribosomal protein LP0 and bacterial L10 [Source:SGD;Acc:S000004332]" Bcin06g06340 1082 "Bcmsh1, similar to yeast MSH1, DNA-binding protein of the mitochondria; involved in repair of mitochondrial DNA; has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis [Source:SGD;Acc:S000001162]" Bcin06g06350 203 yes Effector(V2)|Effector(V1) Bcnqo1, Quinone oxidoreductase Bcin06g06360 1714 "Bcsnt2, similar to yeast SNT2, Subunit of Snt2C complex, RING finger ubiquitin ligase (E3); physically associates with Ecm5p and Rpd3p; along with Ecm5p, recruits Rpd3p to small number of promoters; colocalizes with Ecm5p, independently of Rpd3p, to promoters of stress response genes upon oxidative stress; involved in ubiquitylation, degradation of excess histones; interacts with Ubc4p; role in regulating genes encoding amine transporters; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000003099]" Bcin06g06370 934 Helicase, C-terminal + DEAD/DEAH box helicase domain + Winged helix-turn-helix DNA-binding domain + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin06g06380 433 Bcdao4, D-amino acid oxidase Bcin06g06390 320 Protein of unknown function DUF3468 Bcin06g06400 140 Major facilitator superfamily domain Bcin06g06410 366 CAZy : CE16PCW hemicellulose//SignalP-noTM Cellulose-binding domain, fungal + GDSL lipase/esterase + SGNH hydrolase-type esterase domain Bcin06g06420 568 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin06g06430 372 GroES (chaperonin 10)-like + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin06g06440 703 "Bchcs1, similar to yeast HCS1, Hexameric DNA polymerase alpha-associated DNA helicase A; involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities [Source:SGD;Acc:S000001500]" Bcin06g06450 686 Bcin06g06460 374 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin06g06470 891 F-box domain + Leucine-rich repeat domain, L domain-like Bcin06g06480 1435 Cys2His2 transcription factor + Homeobox Bchox2, Cys2His2 transcription factor Bcin06g06490 137 Effector(V1) Bcin06g06500 808 Protease Thioredoxin-like fold + Thioredoxin domain + Transglutaminase-like Bcin06g06510 82 SignalP-noTM Bcin06g06520 516 SignalP-noTM FAD linked oxidase, N-terminal + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin06g06530 156 Effector(V1) Bcin06g06540 373 Bcin06g06550 965 WD40 repeat + Small-subunit processome, Utp12 + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin06g06560 318 "Bcarc35, similar to yeast ARC35, Subunit of the ARP2/3 complex; ARP2/3 is required for the motility and integrity of cortical actin patches; required for cortical localization of calmodulin [Source:SGD;Acc:S000005318]" Bcin06g06570 1211 "Bchsh155, similar to yeast HSH155, U2-snRNP associated splicing factor; forms extensive associations with the branch site-3' splice site-3' exon region upon prespliceosome formation; similarity to the mammalian U2 snRNP-associated splicing factor SAP155 [Source:SGD;Acc:S000004901]" Bcin06g06580 688 CAZy : GH78PCW pectin//SignalP-noTM//Early secretome Bacterial alpha-L-rhamnosidase + Six-hairpin glycosidase-like Bcin06g06590 615 yes Transporter BcFrt1, Fructose proton symporter Bcin06g06600 521 Bcin06g06610 905 "Bcutp13, similar to yeast UTP13, Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA [Source:SGD;Acc:S000004212]" Bcin06g06620 346 Bcin06g06630 475 Protease Renal dipeptidase family + Metal-dependent hydrolase Bcin06g06640 899 "Bcrgd2, similar to yeast RGD2, GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000001847]" Bcin06g06650 143 Effector(V1) Bcin06g06660 507 CAZy : GT1 UDP-glucuronosyl/UDP-glucosyltransferase Bcin06g06670 190 SignalP-noTM//Early secretome Bcin06g06680 462 yes Bcaqp1, Aquaporin Bcin06g06690 478 "Bcytm1, similar to yeast YTM1, Constituent of 66S pre-ribosomal particles; forms a complex with Nop7p and Erb1p that is required for maturation of the large ribosomal subunit; has seven C-terminal WD repeats [Source:SGD;Acc:S000005798]" Bcin06g06700 538 Transporter Amino acid/polyamine transporter I + Amino acid permease, conserved site + Amino acid permease/ SLC12A domain Bcin06g06710 212 Effector(V1) Bcin06g06720 246 yes SignalP-noTM//Effector(V2)|Effector(V1) Bcnep1, Similar to necrosis- and ethylene-inducing protein 1 precursor Bcin06g06730 392 Bcin06g06740 828 RZZ complex, subunit Zw10 Bcin06g06750 1069 Protease Peptidase M16, C-terminal domain + Peptidase M16 domain + Metalloenzyme, LuxS/M16 peptidase-like + Peptidase M16, N-terminal Bcin06g06760 1265 "Bcset1, similar to yeast SET1, Histone methyltransferase, subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3K4; Set1p-dependent H3K4 trimethylation recruits Nrd1p, allowing efficient termination of snoRNAs and cryptic unstable transcripts (CUTs) by Nrd1p-Nab3p-Sen1p pathway; modulates histone acetylation levels in promoter proximal regions to ensure efficient Nrd1p-dependent termination; required in transcriptional silencing near telomeres and at silent mating type loci; has a SET domain [Source:SGD;Acc:S000001161]" Bcin06g06770 447 Bcin06g06780 161 Tropomyosin Bcin06g06790 223 "Bcrrp17, similar to yeast RRP17, Component of the pre-60S pre-ribosomal particle; required for cell viability under standard (aerobic) conditions but not under anaerobic conditions; exonuclease required for 5′ end processing of pre-60S ribosomal RNA [Source:SGD;Acc:S000002820]" Bcin06g06800 296 Bcin06g06810 192 Effector(V1) "Bcfcf1, similar to yeast FCF1, Putative PINc domain nuclease; required for early cleavages of 35S pre-rRNA and maturation of 18S rRNA; component of the SSU (small subunit) processome involved in 40S ribosomal subunit biogenesis; copurifies with Faf1p [Source:SGD;Acc:S000002747]" Bcin06g06820 329 SignalP-noTM Bcin06g06830 399 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin06g06840 424 Bcin06g06850 426 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin06g06860 409 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin06g06870 541 Bcin06g06880 529 Transporter "Bcamf1, similar to yeast AMF1, Putative paralog of ATR1; but not required for boron tolerance; member of the DHA2 family of drug:H+ antiporters; YOR378W is not an essential gene [Source:SGD;Acc:S000005905]" Bcin06g06890 600 Zn2/Cys6 + fungal trans transcription factor "Bcrdr1, similar to yeast RDR1, Transcriptional repressor involved in regulating multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins [Source:SGD;Acc:S000005907]" Bcin06g06900 402 Bcin06g06910 632 Heterokaryon incompatibility Bcin06g06920 1095 "Bcrad16, similar to yeast RAD16, Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad7p) during NER; required for NER of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex [Source:SGD;Acc:S000000318]" Bcin06g06930 627 "Bcrad7, similar to yeast RAD7, Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad16p) during NER; required for repair of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex [Source:SGD;Acc:S000003813]" Bcin06g06940 127 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) "Bctrm112, similar to yeast TRM112, Protein involved in methylation of tRNA, rRNA, and translation factors; also involved in ribosome biogenesis; subunit of tRNA methyltransferase (MTase) complexes in combination with Trm9p and Trm11p; interacts with and stabilizes 18S rRNA methyltransferase Bud23p; subunit of complex with Mtq2p that methylates Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000005329]" Bcin06g06950 158 Bcin06g06960 761 Bcin06g06970 372 Bcin06g06980 558 Bcin06g06990 315 NmrA-like domain + NAD(P)-binding domain Bcin06g07000 539 SignalP-noTM Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin06g07010 237 CAZy : CE5PCW hemicellulose//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Cutinase + Alpha/Beta hydrolase fold Bcin06g07020 513 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin06g07030 155 Bcin06g07040 402 Heterokaryon incompatibility Bcin06g07050 246 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Glycoside hydrolase, family 61 Bcin06g07060 174 Bcin06g07070 454 Oxoglutarate/iron-dependent dioxygenase + Zinc finger, GRF-type + Alpha-ketoglutarate-dependent dioxygenase AlkB-like + Alkylated DNA repair protein alkB homologue 3 Bcin06g07080 343 "Bcpex7, similar to yeast PEX7, Peroxisomal signal receptor for peroxisomal matrix proteins; recognizes the N-terminal nonapeptide signal (PTS2); WD repeat protein; defects in human homolog cause lethal rhizomelic chondrodysplasia punctata (RCDP) [Source:SGD;Acc:S000002549]" Bcin06g07090 678 ATP-dependent RNA helicase DEAD-box, conserved site + Helicase, C-terminal + DEAD/DEAH box helicase domain + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin06g07100 367 Bcin06g07110 291 Effector(V2)|Effector(V1) Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin06g07120 454 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin06g07130 324 Bcin06g07140 289 Bcin06g07150 518 SignalP-noTM//Early secretome FAD linked oxidase, N-terminal + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin06g07160 416 Protease Peptidase S58, DmpA + ArgJ-like domain Bcin06g07170 603 Bcin06g07180 326 NAD(P)-binding domain Bcin06g07190 1451 Ankyrin repeat + NACHT nucleoside triphosphatase + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase + Alpha/Beta hydrolase fold Bcin06g07200 871 CDC45 family Bcin06g07210 233 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin06g07220 358 Bcin06g07230 3585 Bcin06g07240 343 "Bccrc1, similar to yeast CRC1, Mitochondrial inner membrane carnitine transporter; required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation [Source:SGD;Acc:S000005626]" Bcin06g07250 400 Bcin06g07260 937 "Bcncl1, similar to yeast NCL1, S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase; methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; increases proportion of tRNALeu(CAA) with m5C at wobble position in response to hydrogen peroxide, causing selective translation of mRNA from genes enriched in TTG codon; loss of NCL1 confers hypersensitivity to oxidative stress; similar to Nop2p and human proliferation associated nucleolar protein p120 [Source:SGD;Acc:S000000120]" Bcin06g07270 241 Effector(V1) "Bcrpb5, similar to yeast RPB5, RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation [Source:SGD;Acc:S000000358]" Bcin06g07280 519 "Bcbfr1, similar to yeast BFR1, Component of mRNP complexes associated with polyribosomes; involved in localization of mRNAs to P bodies; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity [Source:SGD;Acc:S000005724]" Bcin06g07290 268 Effector(V1) Bcin06g07300 550 yes Bcmtg2, Obg GTPase Bcin06g07310 605 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin06g07320 192 EthD domain Bcin06g07330 351 Protease Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin06g07340 550 SignalP-noTM FAD linked oxidase, N-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin06g07350 305 Class II aldolase/adducin N-terminal Bcin06g07360 519 JmjC domain Bcin06g07370 525 Bcin06g07380 318 Acetamidase/Formamidase Bcin06g07390 1254 Armadillo-like helical + Armadillo-type fold + Tubulin-specific chaperone D, C-terminal + Tubulin-folding cofactor D Bcin06g07400 308 Bcin06g07410 176 Effector(V1) Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like + Ubiquitin-conjugating enzyme, active site Bcin06g07420 555 Thiolase-like Bcin06g07430 372 Bcin06g07440 463 "Bcalg1, similar to yeast ALG1, Mannosyltransferase; involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability, mutation is functionally complemented by human ortholog [Source:SGD;Acc:S000000314]" Bcin06g07450 544 Effector(V1) "Bcmsc2, similar to yeast MSC2, Endoplasmic reticulum zinc transporter; part of a heterodimeric transporter with Zrg17p that transfers zinc from the cytosol to the ER lumen; member of the cation diffusion facilitator family of efflux pumps; localizes to ER and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids [Source:SGD;Acc:S000002613]" Bcin06g07460 249 Effector(V2)|Effector(V1) Bcin06g07470 178 BTB/POZ-like + BTB/POZ fold Bcin06g07480 402 S-adenosyl-L-methionine-dependent methyltransferase Bcin06g07490 416 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin06g07500 388 Protease//SignalP-noTM "Bcgpi8, similar to yeast GPI8, ER membrane glycoprotein subunit of the GPI transamidase complex; adds glycosylphosphatidylinositol (GPI) anchors to newly synthesized proteins; human PIG-K protein is a functional homolog [Source:SGD;Acc:S000002739]" Bcin06g07510 649 Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin06g07520 309 Mediator complex, subunit Med4 Bcin06g07530 436 Putative amidoligase enzyme Bcin06g07540 386 Bcin06g07550 410 Bcin06g07560 371 "Bclcp5, similar to yeast LCP5, Essential protein involved in maturation of 18S rRNA; depletion leads to inhibited pre-rRNA processing and reduced polysome levels; localizes primarily to the nucleolus [Source:SGD;Acc:S000000929]" Bcin06g07570 644 Nonaspanin (TM9SF) Bcin06g07580 460 FAD linked oxidase, N-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 Bcin06g07590 1216 SignalP-TM Glycoside hydrolase, family 71 Bcin06g07600 355 Bcin06g07610 440 Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily Bcin07g00010 440 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin07g00020 387 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin07g00030 220 Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin07g00040 355 Bcin07g00050 701 Bcin07g00060 872 SignalP-noTM Tail specific protease + ClpP/crotonase-like domain Bcin07g00070 707 Heterokaryon incompatibility Bcin07g00080 124 Effector(V1) Beta-lactamase-related + Beta-lactamase/transpeptidase-like Bcin07g00090 346 NAD(P)-binding domain Bcin07g00100 638 Heterokaryon incompatibility Bcin07g00110 462 Folliculin Bcin07g00120 538 "Bcdhh1, similar to yeast DHH1, Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping; coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, role in translational repression, mRNA decay, and processing body dynamics; may have a role in mRNA export; C-terminus of Dhh1p interacts with Ngr1p and promotes POR1, but not EDC1 mRNA decay; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000002319]" Bcin07g00130 527 "Bcpri1, similar to yeast PRI1, Subunit of DNA primase; DNA primase is required for DNA synthesis and double-strand break repair [Source:SGD;Acc:S000001447]" Bcin07g00140 231 Bcin07g00150 581 Bcin07g00160 393 CAZy : GH18FCW Glycoside hydrolase, family 18, catalytic domain + Glycoside hydrolase, chitinase active site + Chitinase II + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Chitinase insertion domain Bcin07g00170 318 DnaJ domain Bcin07g00180 779 yes BcGAP1, RAS-GTPase activating protein Bcin07g00190 130 Bcin07g00200 180 Effector(V2)|Effector(V1) Bcin07g00210 485 DDH domain Bcin07g00220 659 Bcin07g00230 1359 Hydantoinase/oxoprolinase + Hydantoinase B/oxoprolinase + Hydantoinaseoxoprolinase, N-terminal Bcin07g00240 225 Effector(V2) Bcin07g00250 270 Bcin07g00260 270 Cysteine dioxygenase type I + RmlC-like cupin domain + RmlC-like jelly roll fold Bcin07g00270 310 Protease//Effector(V2) Alpha/beta hydrolase fold-1 + Epoxide hydrolase-like + Alpha/Beta hydrolase fold Bcin07g00280 526 Protease JAB1/MPN/MOV34 metalloenzyme domain + USP8 dimerisation domain Bcin07g00290 744 Ribosomal RNA adenine methyltransferase KsgA/Erm + rRNA adenine dimethylase-like + S-adenosyl-L-methionine-dependent methyltransferase Bcin07g00300 253 Haemerythrin/HHE cation-binding motif Bcin07g00310 375 Oxoglutarate/iron-dependent dioxygenase + Non-haem dioxygenase N-terminal domain + Isopenicillin N synthase-like Bcin07g00320 97 SignalP-noTM Bcin07g00330 192 Bcin07g00340 328 "Bccar1, similar to yeast CAR1, Arginase, catabolizes arginine to ornithine and urea; expression responds to both induction by arginine and nitrogen catabolite repression; disruption decreases production of carcinogen ethyl carbamate during wine fermentation and also enhances freeze tolerance [Source:SGD;Acc:S000006032]" Bcin07g00350 192 Bcin07g00360 79 Effector(V1) Bcin07g00370 410 P-loop containing nucleoside triphosphate hydrolase Bcin07g00380 1526 Spindle associated + Mto2p-binding domain Bcin07g00390 639 CAZy : GT90 Lipopolysaccharide-modifying protein Bcin07g00400 311 HpcH/HpaI aldolase/citrate lyase domain + Pyruvate/Phosphoenolpyruvate kinase-like domain Bcin07g00410 246 DASH complex subunit Spc34 Bcin07g00420 310 Bcin07g00430 705 "Bctaf12, similar to yeast TAF12, Subunit (61/68 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A [Source:SGD;Acc:S000002552]" Bcin07g00440 579 "Bcrpn3, similar to yeast RPN3, Essential non-ATPase regulatory subunit of the 26S proteasome lid; similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control [Source:SGD;Acc:S000000823]" Bcin07g00450 721 yes Bcsas2, histone acetyltransferase Bcin07g00460 104 Bcin07g00470 73 Effector(V2)|Effector(V1) Stress-associated endoplasmic reticulum protein Bcin07g00480 685 Small acidic protein + Small acidic protein-like domain Bcin07g00490 1011 "Bcapl5, similar to yeast APL5, Delta adaptin-like subunit of the clathrin associated protein complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; suppressor of loss of casein kinase 1 function; the clathrin associated protein complex is also known as AP-3 [Source:SGD;Acc:S000006116]" Bcin07g00500 323 "Bcemc2, similar to yeast EMC2, Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; homologous to worm Y57G7A.10/EMC-2, fly CG17556, human TTC35 [Source:SGD;Acc:S000003848]" Bcin07g00510 937 Bcin07g00520 135 Ribosomal protein L27e + Translation protein SH3-like domain + Ribosomal protein L2 domain 2 + Ribosomal protein L27e, conserved site Bcin07g00530 2541 Bcin07g00540 506 "Bcdia4, similar to yeast DIA4, Probable mitochondrial seryl-tRNA synthetase; mutant displays increased invasive and pseudohyphal growth [Source:SGD;Acc:S000001053]" Bcin07g00550 474 Bcin07g00560 370 NADH:flavin oxidoreductase/NADH oxidase, N-terminal + Aldolase-type TIM barrel Bcin07g00570 187 Bcin07g00580 166 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin07g00590 996 Helicase, C-terminal + Helicase-associated domain + DEAD/DEAH box helicase domain + Domain of unknown function DUF1605 + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin07g00600 106 Effector(V1) Bcin07g00610 1437 "Bcurb2, similar to yeast URB2, Protein required for normal metabolism of the rRNA primary transcript; nucleolar protein; proposed to be involved in ribosome biogenesis [Source:SGD;Acc:S000003802]" Bcin07g00620 366 "Bcabp140, similar to yeast ABP140, AdoMet-dependent tRNA methyltransferase and actin binding protein; C-terminal domain is responsible for 3-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA-Thr and tRNA-Ser and contains an S-adenosylmethionine (AdoMet) binding motif; N-terminal actin binding sequence interacts with actin filaments and localizes to actin patches and cables; N- and C-terminal domains are encoded in separate ORFs that are translated into one protein via a +1 frameshift [Source:SGD;Acc:S000005765]" Bcin07g00630 422 Bcin07g00640 356 Bcin07g00650 277 NAD(P)-binding domain Bcin07g00660 536 Transporter "Bcmup1, similar to yeast MUP1, High affinity methionine permease; integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake [Source:SGD;Acc:S000003287]" Bcin07g00670 432 Bcin07g00680 356 2-nitropropane dioxygenase, NPD + Aldolase-type TIM barrel Bcin07g00690 181 Bcin07g00700 407 CobW/HypB/UreG domain + Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal + P-loop containing nucleoside triphosphate hydrolase Bcin07g00710 638 SignalP-noTM Carbohydrate-binding WSC + Domain of unknown function DUF1996 Bcin07g00720 952 yes Signaling pathway Bpk3, CLK-like serine/threonine protein kinase, autophagy-related gene Bcin07g00730 476 Aminotransferase class-III + Ornithine aminotransferase + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin07g00740 712 CAZy : GT22 "Bcgpi10, similar to yeast GPI10, Integral membrane protein involved in GPI anchor synthesis; putative alpha 1,2 mannosyltransferase required for addition of the third mannose onto the glycosylphosphatidylinositol (GPI) core structure; human PIG-Bp is a functional homolog [Source:SGD;Acc:S000003110]" Bcin07g00750 1013 "Bcsec59, similar to yeast SEC59, Dolichol kinase; catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation [Source:SGD;Acc:S000004615]" Bcin07g00760 1103 Bcin07g00770 513 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin07g00780 323 SignalP-noTM Bcin07g00790 394 Bcin07g00800 467 Bcin07g00810 745 Bcin07g00820 658 Bcin07g00830 119 "Bcsws2, similar to yeast SWS2, Putative mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S13 ribosomal protein; participates in controlling sporulation efficiency; localizes to vacuole in response to H2O2 [Source:SGD;Acc:S000005025]" Bcin07g00840 292 SignalP-noTM//Effector(V2)|Effector(V1) Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site + Cyclophilin-type peptidyl-prolyl cis-trans isomerase + Cyclophilin-like domain Bcin07g00850 82 Effector(V2) Bcin07g00860 473 Bcin07g00870 300 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin07g00880 395 Bcin07g00890 422 CAZy : GH18,CBM1FCW //SignalP-noTM Cellulose-binding domain, fungal + Glycoside hydrolase, family 18, catalytic domain + Glycoside hydrolase, chitinase active site + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin07g00900 299 Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin07g00910 318 Bcin07g00920 310 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin07g00930 607 Bcin07g00940 996 CAZy : GT20 "Bctps2, similar to yeast TPS2, Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex; involved in synthesis of the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002481]" Bcin07g00950 308 SM cluster TdiA-like Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin07g00960 348 SM cluster TdiA-like Bcin07g00970 532 SM cluster TdiA-like Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin07g00980 574 SM cluster TdiA-like Major facilitator superfamily + Major facilitator superfamily domain Bcin07g00990 382 SM cluster TdiA-like O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin07g01000 306 SM cluster TdiA-like 6-phosphogluconate dehydrogenase, NADP-binding + 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + 3-hydroxyisobutyrate dehydrogenase-related + NAD(P)-binding domain Bcin07g01010 932 SM cluster TdiA-like (KE) AMP-dependent synthetase/ligase + Thioesterase + Acyl carrier protein-like + AMP-binding, conserved site + Alpha/Beta hydrolase fold Bcin07g01020 436 SM cluster TdiA-like//Early secretome Lipase, secreted + Putative lysophospholipase + Alpha/Beta hydrolase fold Bcin07g01030 289 Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin07g01040 255 SignalP-noTM Carboxylesterase, type B + Alpha/Beta hydrolase fold Bcin07g01050 831 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain Bcin07g01060 1315 Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily + GAF domain-like Bcin07g01070 471 SignalP-noTM Peptidase S9, prolyl oligopeptidase, catalytic domain + Lipase, secreted + Alpha/Beta hydrolase fold Bcin07g01080 537 Bcdao11, D-amino acid oxidase Bcin07g01090 739 SignalP-noTM Bcin07g01100 334 Protein of unknown function DUF3328 Bcin07g01110 259 SignalP-noTM Mucin-like domain Bcin07g01120 534 "Bcerg5, similar to yeast ERG5, C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs [Source:SGD;Acc:S000004617]" Bcin07g01130 193 Effector(V1) Thiosulphate sulfurtransferase, conserved site + Rhodanese-like domain Bcin07g01140 287 Yip1 domain Bcin07g01150 128 Effector(V2)|Effector(V1) Ubiquitin-like + Ribosomal protein L40e + Ubiquitin conserved site + Ubiquitin + Ubiquitin-related domain Bcin07g01160 565 Early secretome RNA polymerase I transcription initiation factor TAF1B/Rrn7 + Transcription initiation factor Rrn7 Bcin07g01170 165 Translation elongation factor IF5A + Translation protein SH3-like domain + Nucleic acid-binding, OB-fold + Ribosomal protein L2 domain 2 + Translation elongation factor, IF5A, hypusine site + Translation elongation factor, IF5A C-terminal Bcin07g01180 671 "Bcvps52, similar to yeast VPS52, Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; involved in localization of actin and chitin; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p [Source:SGD;Acc:S000002892]" Bcin07g01190 420 "Bcgyp8, similar to yeast GYP8, GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport [Source:SGD;Acc:S000001867]" Bcin07g01200 1367 Quinonprotein alcohol dehydrogenase-like superfamily Bcin07g01210 1056 "Bcfun12, similar to yeast FUN12, Translation initiation factor eIF5B; GTPase that promotes Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; promotes GTP-dependent maturation of 18S rRNA by Nob1p; protein abundance increases in response to DNA replication stress; homolog of bacterial IF2 [Source:SGD;Acc:S000000033]" Bcin07g01220 1021 "Bcpol5, similar to yeast POL5, DNA Polymerase phi; has sequence similarity to the human MybBP1A and weak sequence similarity to B-type DNA polymerases, not required for chromosomal DNA replication; required for the synthesis of rRNA [Source:SGD;Acc:S000000781]" Bcin07g01230 729 Heterokaryon incompatibility Bcin07g01240 275 CAZy : CE5PCW hemicellulose Cutinase + Cutinase, monofunctional + Alpha/Beta hydrolase fold Bcin07g01250 1091 Pentatricopeptide repeat + Tetratricopeptide-like helical domain Bcin07g01260 618 "Bcsrp68, similar to yeast SRP68, Core component of the signal recognition particle (SRP) complex; SRP complex functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane; relocalizes from cytoplasm to the nuclear periphery upon DNA replication stress [Source:SGD;Acc:S000006164]" Bcin07g01270 919 yes BcniaD, Nitrate reductase Bcin07g01280 1260 "Bcnmd2, similar to yeast NMD2, Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance [Source:SGD;Acc:S000001119]" Bcin07g01290 746 Heat shock protein 70 family + Heat shock protein 70, conserved site + Heat shock protein 70kD, peptide-binding domain + Heat shock protein 70kD, C-terminal domain Bcin07g01300 775 yes CAZy : GT2 BcCHSVII, Class VII chitin synthase Bcin07g01310 810 Domain of unknown function DUF4210 + Protein FAM214/SPAC3H8.04, C-terminal Bcin07g01320 223 Bcin07g01330 767 Bcin07g01340 508 Homeodomain-like Bcin07g01350 313 Bcin07g01360 495 Homeobox transcription factor Bchox4, Putative homeobox gene Bcin07g01370 391 Bcin07g01380 1230 Rho GTPase-activating protein domain + Zinc finger, LIM-type + Rho GTPase activation protein Bcin07g01390 1089 "Bcstu1, similar to yeast STU1, Component of the mitotic spindle; binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles [Source:SGD;Acc:S000000130]" Bcin07g01400 322 Uncharacterised protein family, basic secretory protein Bcin07g01410 399 Bcin07g01420 654 Bcin07g01430 511 "Bcsec62, similar to yeast SEC62, Essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; cotranslationally N-acetylated by NatA; other members are Sec63p, Sec62p, Sec66p and Sec72p [Source:SGD;Acc:S000006015]" Bcin07g01440 370 Protein of unknown function DUF3431 Bcin07g01450 768 RNA recognition motif domain + Zinc finger, CCCH-type + PWI domain + Nucleotide-binding alpha-beta plait domain Bcin07g01460 943 CAZy : GH92FCW //SignalP-noTM Alpha-1,2-mannosidase, putative + Six-hairpin glycosidase-like + Glycosyl hydrolase family 92 + Glycoside hydrolase-type carbohydrate-binding, subgroup Bcin07g01470 490 Bcin07g01480 1176 SNF2-related + Helicase, C-terminal + Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Helicase superfamily 1/2, ATP-binding domain + Zinc finger, RING-type, conserved site + P-loop containing nucleoside triphosphate hydrolase + Helicase-like transcription factor Bcin07g01490 321 Bcin07g01491 588 Bcin07g01500 385 Phospholipase C, phosphatidylinositol-specific, Y domain + P-loop containing nucleoside triphosphate hydrolase Bcin07g01510 775 "Bclsb6, similar to yeast LSB6, Type II phosphatidylinositol 4-kinase; binds Las17p, a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization [Source:SGD;Acc:S000003636]" Bcin07g01520 179 Effector(V2)|Effector(V1) Aspartyl/glutamyl-tRNA amidotransferase subunit B-related + Uncharacterised domain YOR215C, mitochondrial Bcin07g01530 179 Bcin07g01540 844 Translation elongation factor EFG, V domain + Elongation factor, GTP-binding domain + Translation elongation factor EFTu/EF1A, domain 2 + Small GTP-binding protein domain + Translation elongation factor EFG/EF2, domain IV + Translation protein, beta-barrel domain + Elongation factor G, III-V domain + Ribosomal protein S5 domain 2-type fold, subgroup + Ribosomal protein S5 domain 2-type fold + P-loop containing nucleoside triphosphate hydrolase + Tr-type G domain, conserved site Bcin07g01550 3251 "Bccsf1, similar to yeast CSF1, Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000004077]" Bcin07g01560 671 Organic solute transporter subunit alpha/Transmembrane protein 184 Bcin07g01570 310 S-adenosyl-L-methionine-dependent methyltransferase Bcin07g01580 652 "Bcnog1, similar to yeast NOG1, Putative GTPase; associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins [Source:SGD;Acc:S000006014]" Bcin07g01590 232 Effector(V2)|Effector(V1) Phosphoribosyltransferase domain + Orotate phosphoribosyl transferase domain + Orotate phosphoribosyltransferase + Phosphoribosyltransferase-like Bcin07g01600 272 Effector(V2) "Bcpaa1, similar to yeast PAA1, Polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and also aralkylamines (e.g. tryptamine, phenylethylamine); may be involved in transcription and/or DNA replication [Source:SGD;Acc:S000002478]" Bcin07g01610 433 Protease "Bcddi1, similar to yeast DDI1, DNA damage-inducible v-SNARE binding protein; role in suppression of protein secretion; may play a role in S-phase checkpoint control; has ubiquitin-associated (UBA), ubiquitin-like (UBL), and retroviral-like proteinase (RVP) domains [Source:SGD;Acc:S000000945]" Bcin07g01620 498 "Bcrrp8, similar to yeast RRP8, Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; methylates adenine (m1A) of the large subunit (LSU) rRNA at position 645; involved in pre-rRNA cleavage at site A2; mutation is synthetically lethal with a gar1 mutation; deletion disrupts telomere maintenance by influencing the expression of neighboring gene STN1 [Source:SGD;Acc:S000002490]" Bcin07g01630 1027 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin07g01640 469 Bcin07g01650 706 Magnesium transporter NIPA Bcin07g01660 359 Bcin07g01670 256 Bcin07g01680 201 Bcin07g01690 574 "Bcade2, similar to yeast ADE2, Phosphoribosylaminoimidazole carboxylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway; red pigment accumulates in mutant cells deprived of adenine [Source:SGD;Acc:S000005654]" Bcin07g01700 322 "Bcrna15, similar to yeast RNA15, Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; required for gene looping and maintenance of genome stability [Source:SGD;Acc:S000003012]" Bcin07g01710 307 Protease//Effector(V2) "Bcphb2, similar to yeast PHB2, Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR) [Source:SGD;Acc:S000003463]" Bcin07g01720 735 Protease//SignalP-noTM Peptidase S9, prolyl oligopeptidase, catalytic domain + WD40/YVTN repeat-like-containing domain + Alpha/Beta hydrolase fold Bcin07g01730 227 Effector(V2)|Effector(V1) Bcin07g01740 601 Bcin07g01750 1203 Bcrdr3, RNA-dependent RNA polymerase Bcin07g01760 712 SH3 domain Bcin07g01770 621 Bcin07g01780 625 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin07g01790 1195 Serralysin-like metalloprotease, C-terminal Bcin07g01800 525 Monopolin complex, subunit Csm1/Pcs1 Bcin07g01810 419 "Bcmsp1, similar to yeast MSP1, Highly-conserved N-terminally anchored AAA-ATPase; distributed in the mitochondrial outer membrane and peroxisomes; involved in mitochondrial protein sorting; functions as an extraction engine in local organelle surveillance to remove and initiate degradation of mistargeted proteins, ensuring fidelity of organelle-specific localization of tail-anchored proteins; contains an N-terminal transmembrane domain and C-terminal cytoplasmic ATPase domain [Source:SGD;Acc:S000003260]" Bcin07g01820 459 BcmetC, Cystathionine beta-lyase Bcin07g01830 367 Bcin07g01840 605 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin07g01850 139 Effector(V2)|Effector(V1) Bcin07g01860 137 Effector(V2)|Effector(V1) BTB/POZ-like + BTB/POZ fold Bcin07g01870 459 Bcin07g01880 1421 Bcin07g01890 409 Dehydrogenase, E1 component + Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y + Thiamin diphosphate-binding fold Bcin07g01900 697 WD40 repeat + F-box domain + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin07g01910 405 "Bcatx2, similar to yeast ATX2, Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation [Source:SGD;Acc:S000005605]" Bcin07g01920 502 "Bchat1, similar to yeast HAT1, Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex; uses the cofactor acetyl coenzyme A to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair [Source:SGD;Acc:S000005922]" Bcin07g01930 301 CID domain + CTD kinase subunit gamma Ctk3, C-terminal + CTD kinase subunit gamma CTK3 Bcin07g01940 123 Bcin07g01950 123 Bcin07g01960 1002 Bcin07g01970 372 DNA repair protein XRCC4, C-terminal Bcin07g01980 233 Ribonuclease H domain + Ribonuclease H-like domain Bcin07g01990 350 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin07g02000 642 "Bcfmp40, similar to yeast FMP40, Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000006143]" Bcin07g02010 561 "Bcscd6, similar to yeast SCD6, Repressor of translation initiation; binds eIF4G through its RGG domain and inhibits recruitment of the preinitiation complex; also contains an Lsm domain; may have a role in RNA processing; overproduction suppresses null mutation in clathrin heavy chain gene CHC1; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000006333]" Bcin07g02020 205 Bcin07g02030 170 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcssvp1, Small Secreted Virulence-Related Protein in Sclerotinia Bcin07g02040 436 Bcin07g02050 391 Bcin07g02060 474 Bcin07g02070 2247 "Bcsnt1, similar to yeast SNT1, Subunit of the Set3C deacetylase complex; interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein; mutant has increased aneuploidy tolerance; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000000629]" Bcin07g02080 373 "Bcdys1, similar to yeast DYS1, Deoxyhypusine synthase; catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric [Source:SGD;Acc:S000001110]" Bcin07g02090 219 Effector(V1) Bcin07g02100 630 "Bcpin4, similar to yeast PIN4, Protein involved in G2/M phase progression and response to DNA damage; interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage [Source:SGD;Acc:S000000147]" Bcin07g02110 544 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site + Cyclophilin-type peptidyl-prolyl cis-trans isomerase + Cyclophilin-like domain Bcin07g02120 751 Heat shock factor (HSF)-type, DNA-binding + Winged helix-turn-helix DNA-binding domain + Heat shock transcription factor family Bcin07g02130 602 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin07g02140 453 Bcin07g02150 143 Effector(V2)|Effector(V1) "Bchtz1, similar to yeast HTZ1, Histone variant H2AZ; exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin; Htz1p-containing nucleosomes facilitate RNA Pol II passage by affecting correct assembly and modification status of RNA Pol II elongation complexes and by favoring efficient nucleosome remodeling [Source:SGD;Acc:S000005372]" Bcin07g02160 381 Bcin07g02170 508 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin07g02180 537 Transporter "Bctpo1, similar to yeast TPO1, Polyamine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; during oxidative stress exports spermine, spermidine from the cell, which controls timing of expression of stress-responsive genes; phosphorylation enhances activity and sorting to the plasma membrane [Source:SGD;Acc:S000003951]" Bcin07g02190 175 SignalP-noTM//Effector(V2)|Effector(V1) Bcin07g02200 199 Effector(V2)|Effector(V1) T-complex 11 Bcin07g02210 482 Bcin07g02220 1525 yes Transporter Bmr3, ABC-transporter Bcin07g02230 106 Bcin07g02240 542 Bcin07g02250 272 Bcin07g02260 421 Bcin07g02270 632 Cell shape determining protein MreB/Mrl Bcin07g02280 249 Protease//SignalP-noTM Peptidase G1 + Concanavalin A-like lectin/glucanase domain Bcin07g02290 289 PIG-P Bcin07g02300 822 WD40 repeat + Striatin, N-terminal + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + G-protein beta WD-40 repeat Bcin07g02310 374 "Bcrad14, similar to yeast RAD14, Protein that recognizes and binds damaged DNA during NER; subunit of Nucleotide Excision Repair Factor 1 (NEF1); contains zinc finger motif; homolog of human XPA protein; NER stands for nucleotide excision repair [Source:SGD;Acc:S000004814]" Bcin07g02320 192 Effector(V2) "Bcpho88, similar to yeast PHO88, Probable membrane protein; involved in phosphate transport; role in the maturation of secretory proteins; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations [Source:SGD;Acc:S000000310]" Bcin07g02330 342 Bcin07g02340 195 Effector(V2)|Effector(V1) BTB/POZ-like + BTB/POZ fold Bcin07g02350 307 Transporter Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin07g02360 553 Bcin07g02370 284 Protease ThiJ/PfpI + Class I glutamine amidotransferase-like Bcin07g02380 261 GINS complex, subunit Sld5 + GINS complex + DNA replication complex GINS protein SLD5, C-terminal Bcin07g02390 136 Effector(V2)|Effector(V1) Bcin07g02400 203 Effector(V1) Bcin07g02410 556 "Bcmih1, similar to yeast MIH1, Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdc28p; homolog of S. pombe cdc25 [Source:SGD;Acc:S000004639]" Bcin07g02420 554 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin07g02430 340 Bcin07g02440 109 Effector(V2)|Effector(V1) Bcin07g02450 588 "Bcutp18, similar to yeast UTP18, Small-subunit processome protein involved in pre-18S rRNA maturation; part of a subunit of the 90S preribosomal particle capable of interacting directly with the 5' ETS of the 35S pre-rRNA; contains WD40 repeats [Source:SGD;Acc:S000003605]" Bcin07g02460 370 SAP domain Bcin07g02470 833 "Bccog4, similar to yeast COG4, Essential component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments [Source:SGD;Acc:S000006309]" Bcin07g02480 1103 yes Transporter Bcpmr1, P-type Ca2? -ATPase Bcin07g02490 662 "Bcmcd1, similar to yeast MCD1, Essential alpha-kleisin subunit of the cohesin complex; required for sister chromatid cohesion in mitosis and meiosis; apoptosis induces cleavage and translocation of a C-terminal fragment to mitochondria; expression peaks in S phase [Source:SGD;Acc:S000002161]" Bcin07g02500 384 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin07g02510 245 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin07g02520 821 Pseudouridine-5'-phosphate glycosidase + Carbohydrate kinase PfkB + Ribokinase-like Bcin07g02530 419 "Bcreg1, similar to yeast REG1, Regulatory subunit of type 1 protein phosphatase Glc7p; involved in negative regulation of glucose-repressible genes; involved in regulation of the nucleocytoplasmic shuttling of Hxk2p; REG1 has a paralog, REG2, that arose from the whole genome duplication [Source:SGD;Acc:S000002435]" Bcin07g02540 629 Bcin07g02550 691 CAZy : GH15Energy Six-hairpin glycosidase-like + Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family + Six-hairpin glycosidase Bcin07g02560 646 "Bcymd8, similar to yeast YMD8, Putative nucleotide sugar transporter; has similarity to Vrg4p [Source:SGD;Acc:S000004502]" Bcin07g02570 608 "Bcrtg2, similar to yeast RTG2, Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p [Source:SGD;Acc:S000003221]" Bcin07g02580 755 Protein of unknown function DUF1750, fungi Bcin07g02590 546 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin07g02600 376 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin07g02610 530 yes BcPGD, 6-phosphogluconate dehydrogenase Bcin07g02620 211 Effector(V2)|Effector(V1) Bcin07g02630 283 Effector(V2) Bcin07g02640 522 Diacylglycerol kinase, catalytic domain + NAD kinase/diacylglycerol kinase-like domain Bcin07g02650 422 CAZy : GH5PCW/FCW //SignalP-noTM//Early secretome Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin07g02660 206 Effector(V1) Bcin07g02670 600 CAZy : GH71,CBM24,CBM24FCW //SignalP-noTM Glycoside hydrolase, family 71 Bcin07g02680 111 Tubulin binding cofactor A Bcin07g02690 377 THO complex subunit 7/Mft1 Bcin07g02700 399 RNA polymerase II transcription factor SIII, subunit A Bcin07g02710 77 Ubiquitin-like + Ubiquitin conserved site + Ubiquitin + Ubiquitin-related domain Bcin07g02720 791 Bcin07g02730 783 CAZy : GH55FCW //SignalP-noTM//Early secretome Pectin lyase fold/virulence factor + Pectin lyase fold + Pectate lyase superfamily protein Bcin07g02740 373 CAZy : GH105PCW pectin Six-hairpin glycosidase-like + Glycosyl hydrolase, family 88 + Six-hairpin glycosidase Bcin07g02750 705 AMP-dependent synthetase/ligase + Acetoacetyl-CoA synthase + AMP-binding, conserved site Bcin07g02760 186 Bcin07g02770 612 "Bccdc16, similar to yeast CDC16, Subunit of the anaphase-promoting complex/cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; required for sporulation; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000001505]" Bcin07g02780 269 "Bcyju2, similar to yeast YJU2, Essential protein required for pre-mRNA splicing; associates transiently with the spliceosomal NTC (nineteen complex) and acts after Prp2p to promote the first catalytic reaction of splicing [Source:SGD;Acc:S000001578]" Bcin07g02790 1043 AMP-dependent synthetase/ligase + Acyl carrier protein-like + Male sterility, NAD-binding + NAD(P)-binding domain + AMP-binding, conserved site Bcin07g02800 247 AIG2-like + Butirosin biosynthesis, BtrG-like Bcin07g02810 410 SignalP-noTM Bcin07g02820 663 "Bcmet12, similar to yeast MET12, Protein with MTHFR activity in vitro; null mutant has no phenotype and is prototrophic for methionine; MET13 encodes major isozyme of methylenetetrahydrofolate reductase (MTHFR) [Source:SGD;Acc:S000005944]" Bcin07g02830 243 Bcin07g02840 533 Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin07g02850 282 Protease Glutamine amidotransferase + Class I glutamine amidotransferase-like Bcin07g02860 332 SignalP-noTM//Early secretome Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin07g02870 402 "Bcgtr1, similar to yeast GTR1, Cytoplasmic GTPase; forms a heterodimer with Gtr2p to stimulate TORC1 in response to amino acids; component of GSE complex, which is required for sorting of Gap1p; involved in phosphate transport and telomeric silencing; similar to human RagA and RagB [Source:SGD;Acc:S000004590]" Bcin07g02880 588 Heterokaryon incompatibility Bcin07g02890 326 Effector(V2) Bcin07g02900 1379 Transporter//SM cluster PKS8 ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin07g02910 262 SM cluster PKS8 Serine hydrolase FSH + Alpha/Beta hydrolase fold Bcin07g02920 2249 yes SM cluster PKS8 (KE) Bcpks8, Polyketide synthase Bcin07g02930 658 Low temperature requirement A Bcin07g02940 344 SignalP-noTM Kelch repeat type 1 + Kelch-type beta propeller + Galactose oxidase, beta-propeller Bcin07g02950 139 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin07g02960 515 Helix-loop-helix (HLH) transcription factor Myc-type, basic helix-loop-helix (bHLH) domain Bcin07g02970 495 CAZy : GT69 Mannosyltransferase 1, CMT1 Bcin07g02980 373 NADH:flavin oxidoreductase/NADH oxidase, N-terminal + Aldolase-type TIM barrel Bcin07g02990 704 ARS binding protein 2 Bcin07g03000 311 Transporter Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin07g03010 725 Helicase, C-terminal + DNA helicase, ATP-dependent, RecQ type + DEAD/DEAH box helicase domain + Winged helix-turn-helix DNA-binding domain + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin07g03020 296 Meiotically up-regulated gene 163 protein/YGR053C Bcin07g03030 201 Effector(V2)|Effector(V1) Small GTPase superfamily + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin07g03040 603 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin07g03050 1462 yes BcKDM1, putative H3K36 demethylase Bcin07g03060 458 Bcin07g03070 86 CBF/NF-Y/archaeal histone transcription factor//Effector(V2)|Effector(V1) Histone-fold + Centromere protein W Bcin07g03080 883 Protease Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase + Peptidase M1, membrane alanine aminopeptidase, N-terminal + ERAP1-like C-terminal domain Bcin07g03090 384 Phytanoyl-CoA dioxygenase Bcin07g03100 282 Bcin07g03110 512 MmgE/PrpD + 2-methylcitrate dehydratase PrpD Bcin07g03120 127 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin07g03130 426 "Bchis5, similar to yeast HIS5, Histidinol-phosphate aminotransferase; catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts [Source:SGD;Acc:S000001378]" Bcin07g03140 426 Bcin07g03150 627 Zinc finger, CCHC-type + Zinc knuckle CX2CX3GHX4C Bcin07g03160 144 Effector(V1) "Bcaps2, similar to yeast APS2, Small subunit of the clathrin-associated adaptor complex AP-2; AP-2 is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex [Source:SGD;Acc:S000003819]" Bcin07g03170 346 Reticulon Bcin07g03180 272 Bcin07g03190 366 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin07g03200 565 Bcin07g03210 640 Ankyrin repeat + Ankyrin repeat-containing domain Bcin07g03220 176 Effector(V2)|Effector(V1) Carbonic anhydrase Bcin07g03230 342 NmrA-like domain + NAD(P)-binding domain Bcin07g03240 325 "Bcist1, similar to yeast IST1, Protein with positive role in the multivesicular body sorting pathway; functions and forms a complex with Did2p; recruitment to endosomes is mediated by the Vps2p-Vps24p subcomplex of ESCRT-III; also interacts with Vps4p [Source:SGD;Acc:S000005209]" Bcin07g03250 1247 Domain of unknown function DUF2422 + Brefeldin A-sensitivity protein 4 Bcin07g03260 675 yes SignalP-noTM BcCFEM, non-GPCR membrane-bound CFEM protein Bcin07g03270 514 Bcin07g03280 402 CAZy : CE16PCW hemicellulose//Early secretome GDSL lipase/esterase + SGNH hydrolase-type esterase domain Bcin07g03290 437 Acyl-CoA oxidase/dehydrogenase, central domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase/oxidase, N-terminal Bcin07g03300 1364 Inner centromere protein, ARK-binding domain Bcin07g03310 1065 DnaJ domain + DnaJ domain, conserved site Bcin07g03320 140 Bcin07g03330 1333 Bcin07g03340 1102 Protease Bcnma, Trypsin-like serine protease Bcin07g03350 176 Effector(V1) Bcin07g03360 128 Bcin07g03370 82 Effector(V1) Bcin07g03380 1023 Rab-GTPase-TBC domain Bcin07g03390 1823 "Bctop2, similar to yeast TOP2, Topoisomerase II; relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis; required for replication slow zone (RSZ) breakage following Mec1p inactivation [Source:SGD;Acc:S000005032]" Bcin07g03400 612 "Bcxbp1, similar to yeast XBP1, Transcriptional repressor; binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000001363]" Bcin07g03410 418 "Bccns1, similar to yeast CNS1, TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and stimulates the ATPase activity of SSA1, ts mutants reduce Hsp82p function while over expression suppresses the phenotypes of an HSP82 ts allele and a cpr7 deletion [Source:SGD;Acc:S000000359]" Bcin07g03420 381 Cation efflux protein + Cation efflux protein transmembrane domain Bcin07g03430 285 Bcgst14, Glutathione S-transferase Bcin07g03440 190 EF-hand domain + EF-hand domain pair + EF-Hand 1, calcium-binding site Bcin07g03450 711 Bcin07g03460 381 Oxidative stress survival, Svf1-like + Svf1-like, C-terminal Bcin07g03470 216 Bcgst21, Glutathione S-transferase Bcin07g03480 222 Effector(V2)|Effector(V1) "Bchnt2, similar to yeast HNT2, Dinucleoside triphosphate hydrolase; has similarity to the tumor suppressor FHIT and belongs to the histidine triad (HIT) superfamily of nucleotide-binding proteins [Source:SGD;Acc:S000002713]" Bcin07g03490 587 "Bcsrm1, similar to yeast SRM1, Nucleotide exchange factor for Gsp1p; localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p [Source:SGD;Acc:S000003065]" Bcin07g03500 1177 K Homology domain + K Homology domain, type 1 Bcin07g03510 873 Bcin07g03520 273 HAD hydrolase, subfamily IA + Pyrimidine 5-nucleotidase + HAD-like domain Bcin07g03530 145 "Bcsrb7, similar to yeast SRB7, Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p [Source:SGD;Acc:S000002716]" Bcin07g03540 235 Effector(V2)|Effector(V1) tRNA endonuclease-like domain + Protein of unknown function DUF2034 Bcin07g03550 68 Effector(V2)|Effector(V1) Bcin07g03560 1107 "Bcctf18, similar to yeast CTF18, Subunit of a complex with Ctf8p; shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint [Source:SGD;Acc:S000004683]" Bcin07g03570 613 Zn2/Cys6 + fungal trans transcription factor Bcfow2, Zn2/Cys6 transcription factor Bcin07g03580 564 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin07g03590 155 Effector(V2)|Effector(V1) "Bcfis1, similar to yeast FIS1, Protein involved in mitochondrial fission and peroxisome abundance; required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation [Source:SGD;Acc:S000001327]" Bcin07g03600 198 Effector(V1) Kinetochore-Ndc80 subunit Spc24 Bcin07g03610 244 Bcin07g03620 385 TatD family + Metal-dependent hydrolase Bcin07g03630 629 Bcin07g03640 893 SNF2-related + Helicase, C-terminal + Helicase superfamily 1/2, ATP-binding domain + EF-Hand 1, calcium-binding site + P-loop containing nucleoside triphosphate hydrolase Bcin07g03650 140 Bcin07g03660 157 Bcin07g03670 404 "Bcend3, similar to yeast END3, EH domain-containing protein involved in endocytosis; actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p [Source:SGD;Acc:S000005028]" Bcin07g03680 311 Dual specificity phosphatase, catalytic domain + Protein-tyrosine/Dual specificity phosphatase + Dual specificity phosphatase, subgroup, catalytic domain + Dual specificity phosphatase + Protein-tyrosine phosphatase-like Bcin07g03690 187 Effector(V2)|Effector(V1) Flavin reductase-like, FMN-binding + FMN-binding split barrel Bcin07g03700 367 Bcin07g03710 372 Bcin07g03720 154 Effector(V2)|Effector(V1) Guanine-specific ribonuclease N1/T1 + Ribonuclease/ribotoxin Bcin07g03730 471 Bcin07g03740 808 Bcin07g03750 312 SignalP-noTM//Effector(V1) Bcin07g03760 287 Ketose-bisphosphate aldolase, class-II + Aldolase-type TIM barrel Bcin07g03770 321 CAZy : GH16FCW //SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin07g03780 527 yes Transporter Bchxt15, Hexose transporter 15 Bcin07g03790 67 Bcin07g03800 163 Effector(V2)|Effector(V1) Velvet factor Bcin07g03810 687 Arginine-tRNA ligase + Aminoacyl-tRNA synthetase, class I, conserved site + Arginyl tRNA synthetase N-terminal domain + DALR anticodon binding + Aminoacyl-tRNA synthetase, class 1a, anticodon-binding + Rossmann-like alpha/beta/alpha sandwich fold Bcin07g03820 330 SignalP-noTM NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin07g03830 686 Malic oxidoreductase + Malic enzyme, N-terminal domain + Malic enzyme, NAD-binding + NAD(P)-binding domain Bcin07g03840 1412 Protein kinase domain + Protein kinase-like domain Bcin07g03850 111 Effector(V2)|Effector(V1) Bcin07g03860 115 Bcin07g03870 139 Bcin07g03880 496 Bcin07g03890 656 Bcin07g03900 188 Effector(V2)|Effector(V1) Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin07g03910 471 Bcin07g03920 575 "Bcrio1, similar to yeast RIO1, Serine kinase involved in cell cycling and pre-rRNA processing; associated with late pre-40S particles via its conserved C-terminal domain and participates in late 40S biogenesis; association with pre-40S particles regulated by its catalytic ATPase site and likely occurs after the release of Rio2p from these particles; involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA; essential gene [Source:SGD;Acc:S000005645]" Bcin07g03930 1227 "Bcsmc3, similar to yeast SMC3, Subunit of the multiprotein cohesin complex; required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member [Source:SGD;Acc:S000003610]" Bcin07g03940 1524 Bcin07g03950 607 "Bcdbp9, similar to yeast DBP9, DEAD-box protein required for 27S rRNA processing; exhibits DNA, RNA and DNA/RNA helicase activities; ATPase activity shows preference for DNA over RNA; DNA helicase activity abolished by mutation in RNA-binding domain [Source:SGD;Acc:S000004266]" Bcin07g03960 175 Effector(V2) Bcin07g03970 397 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin07g03980 412 CAZy : AA11 //SignalP-noTM Bcin07g03990 288 "Bcyih1, similar to yeast YIH1, Negative regulator of eIF2 kinase Gcn2p; competes with Gcn2p for binding to Gcn1p; may contribute to regulation of translation in response to starvation via regulation of Gcn2p; binds to monomeric actin and to ribosomes and polyribosomes; ortholog of mammalian IMPACT [Source:SGD;Acc:S000000655]" Bcin07g04000 846 CAZy : GH92FCW //SignalP-noTM//Early secretome Alpha-1,2-mannosidase, putative + Six-hairpin glycosidase-like + Glycosyl hydrolase family 92 + Glycoside hydrolase-type carbohydrate-binding, subgroup Bcin07g04010 53 Effector(V1) Bcin07g04020 368 Bcin07g04030 251 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin07g04040 779 Tetrapeptide transporter, OPT1/isp4 + Oligopeptide transporter, OPT superfamily Bcin07g04050 749 Bcin07g04060 223 Effector(V2)|Effector(V1) Bcin07g04070 102 EthD domain + Dimeric alpha-beta barrel Bcin07g04080 504 Bcin07g04090 375 Bcin07g04100 399 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin07g04110 70 Effector(V2) Bcin07g04120 237 Bcin07g04130 905 Glucose/ribitol dehydrogenase + MaoC-like domain + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site + HotDog domain Bcin07g04140 179 Effector(V2)|Effector(V1) Bcin07g04150 317 P-loop containing nucleoside triphosphate hydrolase Bcin07g04160 520 Extracellular mutant protein 11, C-terminal Bcin07g04170 700 AMP-dependent synthetase/ligase + AMP-binding, conserved site Bcin07g04180 308 "Bcrkm5, similar to yeast RKM5, Protein lysine methyltransferase; monomethylates Lys-46 of the ribosomal large subunit Rpl1a/Rpl1b; member of the seven beta-strand methyltransferase superfamily; orthologs only found among fungal species [Source:SGD;Acc:S000004127]" Bcin07g04190 241 Zn2/Cys6 transcription factor//Effector(V2)|Effector(V1) Zn(2)-C6 fungal-type DNA-binding domain Bcin07g04200 435 Cys2His2 transcription factor BccreA, Carbon catabolite repression regulator, Cys2His2 transcription factor Bcin07g04210 195 Bcin07g04220 411 Cytochrome P450 Bcin07g04230 363 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin07g04240 247 Effector(V2)|Effector(V1) Bcin07g04250 886 "Bcorc4, similar to yeast ORC4, Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; ORC4 has a paralog, RIF2, that arose from the whole genome duplication [Source:SGD;Acc:S000006366]" Bcin07g04260 975 Bcin07g04270 1043 "Bcsec5, similar to yeast SEC5, Essential 107kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion; involved in assembly of the exocyst complex; required with Sec3p for ER inheritance where it promotes anchoring of the cortical ER at the bud tip [Source:SGD;Acc:S000002573]" Bcin07g04280 384 Early secretome "Bcidh2, similar to yeast IDH2, Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase; complex catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; phosphorylated [Source:SGD;Acc:S000005662]" Bcin07g04290 529 Early secretome Bchap1, Phytase Bcin07g04300 295 "Bcrot1, similar to yeast ROT1, Molecular chaperone involved in protein folding in ER; mutation causes defects in cell wall synthesis and lysis of autophagic bodies, suppresses tor2 mutations, and is synthetically lethal with kar2-1 and with rot2 mutations; involved in N-linked glycosylation and O-mannosylation; transmembrane helix Ser250 is essential for Rot1p to interact with other membrane components and exert its functional role, avoiding exposure of Ser H-bonding group at lipid-exposed surface [Source:SGD;Acc:S000004813]" Bcin07g04310 246 Effector(V1) "Bcfau1, similar to yeast FAU1, 5,10-methenyltetrahydrofolate synthetase; involved in folic acid biosynthesis [Source:SGD;Acc:S000000985]" Bcin07g04320 94 Effector(V2)|Effector(V1) "Bcsme1, similar to yeast SME1, Core Sm protein Sm E; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm E [Source:SGD;Acc:S000005685]" Bcin07g04330 970 "Bcmtr10, similar to yeast MTR10, Nuclear import receptor; mediates the nuclear localization of proteins involved in mRNA-nucleus export; promotes dissociation of mRNAs from the nucleus-cytoplasm mRNA shuttling protein Npl3p; required for retrograde import of mature tRNAs; relocalizes from cytoplasm to the nuclear periphery upon DNA replication stress [Source:SGD;Acc:S000005686]" Bcin07g04340 725 Bcin07g04350 630 SignalP-TM Calcineurin-like phosphoesterase domain, apaH type + Sphingomyelin phosphodiesterase + Metallo-dependent phosphatase-like Bcin07g04360 280 Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin07g04370 756 SignalP-noTM//Early secretome ClpP/crotonase-like domain Bcin07g04380 149 Effector(V1) Bcin07g04390 342 Bcin07g04400 409 Bcdao12, D-amino acid oxidase Bcin07g04410 576 MOB kinase activator family Bcin07g04420 415 CobW/HypB/UreG domain + Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal + P-loop containing nucleoside triphosphate hydrolase Bcin07g04430 842 "Bcsst2, similar to yeast SST2, GTPase-activating protein for Gpa1p; regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family [Source:SGD;Acc:S000004444]" Bcin07g04440 294 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin07g04450 193 Effector(V1) Bcin07g04460 551 Bcsox1, Sulfite oxidase 1 Bcin07g04470 133 Effector(V1) GroES (chaperonin 10)-like Bcin07g04480 553 Low affinity iron permease, Fet4 Bcin07g04490 866 Protein kinase domain + AGC-kinase, C-terminal + Protein kinase-like domain + Protein kinase, ATP binding site Bcin07g04500 487 Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain + Peptidyl-prolyl cis-trans isomerase, FKBP-type + FK506-binding protein Bcin07g04510 251 Effector(V1) Class I glutamine amidotransferase-like + ThiJ/PfpI Bcin07g04520 199 Bcin07g04530 587 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin07g04540 121 Effector(V2)|Effector(V1) RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain + SF3B14, RNA recognition motif Bcin07g04550 42 Effector(V2)|Effector(V1) Bcin07g04560 386 Protein of unknown function DUF3661, vaculolar transmembrane Bcin07g04570 452 CAZy : GT1 UDP-glucuronosyl/UDP-glucosyltransferase Bcin07g04580 410 Bcin07g04590 630 "Bchts1, similar to yeast HTS1, Cytoplasmic and mitochondrial histidine tRNA synthetase; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence; mutations in human ortholog HARS2 are associated with Perrault syndrome [Source:SGD;Acc:S000006237]" Bcin07g04600 665 "Bcvps33, similar to yeast VPS33, ATP-binding protein that is a subunit of the HOPS and CORVET complexes; essential for protein sorting, vesicle docking, and fusion at the vacuole; binds to SNARE domains [Source:SGD;Acc:S000004388]" Bcin07g04610 1076 HMG (high mobility group) transcription factor Amine oxidase + SWIRM domain + Homeodomain-like + High mobility group box domain + Winged helix-turn-helix DNA-binding domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin07g04620 283 yes BcCPB1, Bccap2, F-actin capping protein Bcin07g04630 379 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin07g04640 672 Major facilitator superfamily domain + Autophagy-related protein 22-like Bcin07g04650 1179 "Bcrgr1, similar to yeast RGR1, Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for glucose repression, HO repression, RME1 repression and sporulation [Source:SGD;Acc:S000004061]" Bcin07g04660 774 Protease Peptidase C19, ubiquitin carboxyl-terminal hydrolase + Ubiquitin specific protease, conserved site + Ubiquitin specific protease domain Bcin07g04670 85 Effector(V1) "Bcyos1, similar to yeast YOS1, Integral membrane protein required for ER to Golgi transport; localized to the Golgi, the ER, and COPII vesicles; interacts with Yip1p and Yif1p [Source:SGD;Acc:S000007651]" Bcin07g04680 631 CAZy : GT22 //SignalP-noTM "Bcalg12, similar to yeast ALG12, Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2, acts in the dolichol pathway for N-glycosylation [Source:SGD;Acc:S000005313]" Bcin07g04690 297 "Bcatp3, similar to yeast ATP3, Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis [Source:SGD;Acc:S000000243]" Bcin07g04700 912 "Bctop1, similar to yeast TOP1, Topoisomerase I; nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination; role in processing ribonucleoside monophosphates in genomic DNA into irreversible single-strand breaks [Source:SGD;Acc:S000005366]" Bcin07g04710 500 "Bccoq6, similar to yeast COQ6, Putative flavin-dependent monooxygenase; involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes; human COX6 can rescue a yeast cox6 mutant and is implicated in steroid-resistant nephrotic syndrome (SRNS) [Source:SGD;Acc:S000003487]" Bcin07g04720 158 Effector(V2)|Effector(V1) Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like Bcin07g04730 420 Bccmk1, Ca2-dependent kinase Bcin07g04740 582 Restriction of telomere capping protein 4, C-terminal Bcin07g04750 434 Dynamitin Bcin07g04760 642 Transporter Major facilitator superfamily domain Bcin07g04770 565 SignalP-noTM PA14 + GLEYA adhesin domain Bcin07g04780 533 "Bcaro8, similar to yeast ARO8, Aromatic aminotransferase I; expression is regulated by general control of amino acid biosynthesis [Source:SGD;Acc:S000003170]" Bcin07g04790 642 Protease Carboxylesterase, type B + Alpha/Beta hydrolase fold Bcin07g04800 519 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin07g04810 599 CAZy : GH20FCW //SignalP-noTM//Early secretome Glycoside hydrolase, catalytic domain + Glycoside hydrolase family 20, catalytic core + Glycoside hydrolase superfamily + Beta-hexosaminidase + Chitobiase/beta-hexosaminidase domain 2-like + Beta-hexosaminidase, eukaryotic type, N-terminal Bcin07g04820 504 "Bcnab2, similar to yeast NAB2, Nuclear polyadenylated RNA-binding protein; required for nuclear mRNA export and poly(A) tail length control; binds nuclear pore protein Mlp1p; involved in forming export-competent mRNPs in the nucleus; autoregulates mRNA levels; related to human hnRNPs; nuclear localization sequence binds Kap104p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003090]" Bcin07g04830 617 "Bchem14, similar to yeast HEM14, Protoporphyrinogen oxidase; a mitochondrial enzyme that catalyzes the seventh step in the heme biosynthetic pathway, converting protoporphyrinogen IX to protoporphyrin IX; inhibited by diphenyl ether-type herbicides [Source:SGD;Acc:S000000816]" Bcin07g04840 251 O-methyltransferase, family 3 + S-adenosyl-L-methionine-dependent methyltransferase Bcin07g04850 706 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin07g04860 251 Dienelactone hydrolase + Alpha/Beta hydrolase fold Bcin07g04870 376 yes CAZy : GH16FCW //SignalP-noTM Bccrh4, Chitin transglycosylase Bcin07g04880 442 "Bcsfh5, similar to yeast SFH5, Non-classical phosphatidylinositol transfer protein (PITP); exhibits PI- but not PC-transfer activity; localizes to the peripheral endoplasmic reticulum, cytosol and microsomes; similar to Sec14p; partially relocalizes to the plasma membrane upon DNA replication stress [Source:SGD;Acc:S000003681]" Bcin07g04890 1168 Protease "Bcubp15, similar to yeast UBP15, Ubiquitin-specific protease involved in protein deubiquitination; catalytic activity regulated by an N-terminal TRAF-like domain and and C-terminal sequences; physically interacts with anaphase-promoting complex/cyclosome (APC/C) activator, Cdh1p; forms a complex with AAA peroxins Pex1p and Pex6p [Source:SGD;Acc:S000004920]" Bcin07g04900 210 SignalP-noTM//Effector(V2)|Effector(V1) GOLD + TMP21-related Bcin07g04910 575 "Bcprp45, similar to yeast PRP45, Protein required for pre-mRNA splicing; associates with the spliceosome and interacts with splicing factors Prp22p and Prp46p; orthologous to human transcriptional coactivator SKIP and can activate transcription of a reporter gene [Source:SGD;Acc:S000000030]" Bcin07g04920 368 CAZy : GH16FCW Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin07g04930 172 Effector(V2)|Effector(V1) "Bctim22, similar to yeast TIM22, Essential core component of the mitochondrial TIM22 complex; involved in insertion of polytopic proteins into the inner membrane; forms the channel through which proteins are imported [Source:SGD;Acc:S000002376]" Bcin07g04940 537 Major facilitator superfamily + Major facilitator superfamily domain Bcin07g04950 496 Domain of unknown function DUF4243 Bcin07g04960 625 Alkaline phosphatase D-related + Metallo-dependent phosphatase-like Bcin07g04970 476 Bcin07g04980 1737 Bcin07g04990 258 Effector(V2)|Effector(V1) BcABA4-like, Dehydrogenase/reductase Bcin07g05000 124 Bcin07g05010 272 Effector(V2) Bcin07g05020 388 Bcin07g05030 396 "Bcufd1, similar to yeast UFD1, Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase; polyubiquitin binding protein that assists in the dislocation of misfolded, ERAD substrates that are subsequently delivered to the proteasome for degradation; involved in regulated destruction of ER membrane proteins such as HMG-CoA reductase (Hmg1/2p) and cytoplasmic proteins (Fbp1p); involved in mobilizing membrane bound transaction factors by regulated Ub/proteasome-dependent processing (RUP) [Source:SGD;Acc:S000003280]" Bcin07g05040 480 GYF Bcin07g05050 470 AAA+ ATPase domain + TIP49, C-terminal + RuvB-like + P-loop containing nucleoside triphosphate hydrolase Bcin07g05060 905 Bcin07g05070 310 "Bcbrx1, similar to yeast BRX1, Nucleolar protein; constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif [Source:SGD;Acc:S000005437]" Bcin07g05080 211 Bcin07g05090 213 Effector(V2)|Effector(V1) Small GTPase superfamily + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin07g05100 1218 Zinc finger, CCCH-type + Chromo/chromo shadow domain + Chromo domain-like + Chromo domain, conserved site + Chromo domain Bcin07g05110 718 "Bcnop2, similar to yeast NOP2, rRNA m5C methyltransferase; methylates cytosine at position 2870 of 25S rRNA while Rcm1p methylates cytosine at position 2278; contains seven beta-strand methyltransferase motif; essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; localized to the nucleolus; constituent of 66S pre-ribosomal particles; homolog of p120/NSUN1, a human gene upregulated in cancer [Source:SGD;Acc:S000005005]" Bcin07g05120 206 Effector(V1) Ubiquitin-like + Ubiquitin-related domain Bcin07g05130 156 Effector(V2)|Effector(V1) "Bccof1, similar to yeast COF1, Cofilin, involved in pH-dependent actin filament depolarization; binds both actin monomers and filaments and severs filaments; involved in the selective sorting, export of the secretory cargo from the late golgi; genetically interacts with pmr1; thought to be regulated by phosphorylation at SER4; ubiquitous and essential in eukaryotes [Source:SGD;Acc:S000003973]" Bcin07g05140 582 "Bchsp60, similar to yeast HSP60, Tetradecameric mitochondrial chaperonin; required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated [Source:SGD;Acc:S000004249]" Bcin07g05160 707 Bcin07g05170 296 Bcin07g05180 224 Effector(V2)|Effector(V1) Bcin07g05190 167 Effector(V1) Bcin07g05200 319 Bcin07g05210 335 BTB/POZ-like Bcin07g05220 264 Bcin07g05230 169 Effector(V2)|Effector(V1) Bcin07g05240 359 Inositol-pentakisphosphate 2-kinase Bcin07g05250 563 Mitochondrial distribution and morphology protein 34 Bcin07g05260 255 "Bcyaf9, similar to yeast YAF9, Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes; may function to antagonize silencing near telomeres; interacts directly with Swc4p; has homology to human leukemogenic protein AF9; contains a YEATS domain [Source:SGD;Acc:S000005051]" Bcin07g05270 289 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin07g05280 305 mRNA splicing factor SYF2 Bcin07g05290 242 Bcin07g05300 440 Bcin07g05310 688 Bcin07g05320 407 Bcin07g05330 568 Bcin07g05340 944 Bcin07g05350 114 Effector(V1) Bcin07g05360 444 Bcin07g05370 139 Bcin07g05380 233 Bcin07g05390 236 Bcin07g05400 805 CAZy : GH78PCW pectin Bacterial alpha-L-rhamnosidase + Six-hairpin glycosidase-like + Galactose-binding domain-like + Bacterial alpha-L-rhamnosidase N-terminal Bcin07g05410 539 Transporter General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin07g05420 319 Bcin07g05430 490 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin07g05440 592 SignalP-noTM Bcin07g05450 511 Transporter Sugar/inositol transporter + General substrate transporter + Major facilitator superfamily domain Bcin07g05460 415 Bcin07g05470 2351 CbxX/CfqX + AAA+ ATPase domain + ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin07g05480 973 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger, C2H2-like + Zinc finger C2H2-type/integrase DNA-binding domain Bcin07g05490 472 yes Bcent, Equilibrative nucleoside transporter Bcin07g05500 562 Metallo-dependent phosphatase-like Bcin07g05510 350 "Bctlg2, similar to yeast TLG2, Syntaxin-like t-SNARE; forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16) [Source:SGD;Acc:S000005378]" Bcin07g05520 149 Bc4, Calmodulin Bcin07g05530 633 CAZy : GH47 Glycoside hydrolase, family 47 Bcin07g05540 2941 Bcin07g05550 804 Bcin07g05560 347 Bcin07g05570 604 Protein kinase-like domain + Domain of unknown function DUF3635 Bcin07g05580 449 Protein of unknown function DUF1682 Bcin07g05590 421 Putative amidoligase enzyme Bcin07g05600 114 Bcin07g05610 180 Effector(V1) "Bcmnp1, similar to yeast MNP1, Protein associated with the mitochondrial nucleoid; putative mitochondrial ribosomal protein with similarity to E. coli L7/L12 ribosomal protein; required for normal respiratory growth [Source:SGD;Acc:S000003036]" Bcin07g05620 4960 "Bcmdn1, similar to yeast MDN1, Huge dynein-related AAA-type ATPase (midasin); forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p); acts in removal of ribosomal biogenesis factors at successive steps of pre-60S assembly and export from nucleus [Source:SGD;Acc:S000004096]" Bcin07g05630 681 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin07g05640 606 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin07g05650 165 Effector(V2)|Effector(V1) Bcin07g05660 675 CCAAT transcription factor "Bcnoc3, similar to yeast NOC3, Subunit of a nuclear complex with Noc2p and pre-replicative complexes; the Noc2p-Noc3p complex binds to 66S ribosomal precursors to mediate their maturation and intranuclear transport; binds to chromatin at active replication origins, and is required for pre-RC formation and maintenance during DNA replication licensing [Source:SGD;Acc:S000003992]" Bcin07g05670 188 Effector(V2)|Effector(V1) "Bcnip7, similar to yeast NIP7, Nucleolar protein required for 60S ribosome subunit biogenesis; constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p [Source:SGD;Acc:S000006132]" Bcin07g05680 689 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin07g05690 396 Bcin07g05700 615 "Bcmrh4, similar to yeast MRH4, Mitochondrial ATP-dependent RNA helicase of the DEAD-box family; required for assembly of the large subunit of mitochondrial ribosomes; binds to the large subunit rRNA, 21S_rRNA; localizes to the matrix face of the mitochondrial inner membrane and associates with the large subunit precursor and with mature ribosomes [Source:SGD;Acc:S000003032]" Bcin07g05710 749 AAA+ ATPase domain + ATPase, AAA-type, core + ATPase, AAA-type, conserved site + BCS1, N-terminal + P-loop containing nucleoside triphosphate hydrolase Bcin07g05720 1538 Protease "Bcubp12, similar to yeast UBP12, Ubiquitin-specific protease; cleaves ubiquitin from ubiquitinated proteins; present in the nucleus and cytoplasm [Source:SGD;Acc:S000003733]" Bcin07g05730 66 Effector(V2)|Effector(V1) Bcin07g05740 153 SignalP-noTM//Effector(V2)|Effector(V1) Bcin07g05750 313 "Bccbr1, similar to yeast CBR1, Microsomal cytochrome b reductase; not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia [Source:SGD;Acc:S000001305]" Bcin07g05760 211 Protein of unknown function DUF3605 Bcin07g05770 161 "Bcenv10, similar to yeast ENV10, Protein proposed to be involved in vacuolar functions; putative role in secretory protein quality control; mutant shows defect in CPY processing; YLR065C is not an essential gene [Source:SGD;Acc:S000004055]" Bcin07g05780 834 "Bccdc27, similar to yeast CDC27, Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition [Source:SGD;Acc:S000000180]" Bcin07g05790 443 Zinc finger, RING-type + Zinc finger, RING-CH-type + Zinc finger, RING/FYVE/PHD-type Bcin07g05800 743 "Bcprr1, similar to yeast PRR1, Serine/threonine protein kinase; inhibits pheromone induced signaling downstream of MAPK, possibly at the level of the Ste12p transcription factor [Source:SGD;Acc:S000001599]" Bcin07g05810 325 Bcccp2, Cytochrome c peroxidase Bcin07g05820 588 Bcin07g05830 1321 AMP-dependent synthetase/ligase + Phosphopantetheine attachment site + Acyl carrier protein-like + Amino acid adenylation domain + Trimeric LpxA-like + Non-ribosomal peptide synthetase C-terminal + Polyketide synthase, phosphopantetheine-binding domain + AMP-binding, conserved site Bcin07g05840 504 Bcin07g05850 258 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin07g05860 138 Effector(V2)|Effector(V1) Bcin07g05870 676 Heterokaryon incompatibility Bcin07g05880 393 Bcvel4, Velvet-like 4, component of the Velvet protein complex, protein implicated in photoreponses Bcin07g05890 584 Protease CTP synthase + CTP synthase, N-terminal + Glutamine amidotransferase + P-loop containing nucleoside triphosphate hydrolase + Class I glutamine amidotransferase-like Bcin07g05900 887 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain Bcin07g05910 498 Transporter//SignalP-noTM Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin07g05920 1001 "Bcpik1, similar to yeast PIK1, Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton; may control nonselective autophagy and mitophagy through trafficking of Atg9p [Source:SGD;Acc:S000005211]" Bcin07g05930 713 SignalP-noTM Leucine-rich repeat domain, L domain-like Bcin07g05940 125 Effector(V1) Bcin07g05950 516 Ion channel regulatory protein, UNC-93 + Major facilitator superfamily domain Bcin07g05960 308 Bcin07g05970 360 Bcin07g05980 127 Bcin07g05990 424 Bcin07g06000 362 Six-bladed beta-propeller, TolB-like Bcin07g06010 328 "Bcthi4, similar to yeast THI4, Thiazole synthase; abundant protein involved in the formation of the thiazole moiety of thiamine during thiamine biosynthesis; acts more as a co-substrate rather than an enzyme by providing the sulphur source for thiazole formation; undergoes a single turnover only; required for mitochondrial genome stability in response to DNA damaging agents [Source:SGD;Acc:S000003376]" Bcin07g06020 276 Bcin07g06030 413 Protease Epoxide hydrolase-like + Epoxide hydrolase, N-terminal + Epoxide hydrolase + Alpha/Beta hydrolase fold Bcin07g06040 371 Bcin07g06050 125 Cys2His2 transcription factor//Effector(V2)|Effector(V1) Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin07g06060 267 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin07g06070 428 Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase/oxidase, N-terminal Bcin07g06080 384 Bcin07g06090 467 "Bcspo7, similar to yeast SPO7, Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology, premeiotic replication, and sporulation [Source:SGD;Acc:S000000007]" Bcin07g06100 533 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin07g06110 376 Bcalo2, AMID-like oxidoreductase 2 Bcin07g06120 1043 Cys2His2 transcription factor + Fungal_trans Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin07g06130 185 Effector(V1) Histone deacetylase complex subunit SAP30/SAP30-like + Histone deacetylase complex subunit SAP30, Sin3 binding domain Bcin07g06140 524 "Bcmdj1, similar to yeast MDJ1, Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones [Source:SGD;Acc:S000001878]" Bcin07g06150 994 "Bcbro1, similar to yeast BRO1, Cytoplasmic class E vacuolar protein sorting (VPS) factor; coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes [Source:SGD;Acc:S000006005]" Bcin07g06160 1102 Protease "Bcpim1, similar to yeast PIM1, ATP-dependent Lon protease; involved in degradation of misfolded proteins in mitochondria; required for biogenesis and maintenance of mitochondria [Source:SGD;Acc:S000000118]" Bcin07g06170 767 Protein kinase domain + Protein kinase-like domain Bcin07g06180 610 Xanthine/uracil permease + Xanthine/uracil/vitamin C permease Bcin07g06190 290 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin07g06200 472 Paired amphipathic helix Bcin07g06210 714 WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + Domain of unknown function DUF2415 Bcin07g06220 679 Chaperone DnaK + Heat shock protein 70 family + Heat shock protein 70, conserved site + Heat shock protein 70kD, peptide-binding domain + Heat shock protein 70kD, C-terminal domain Bcin07g06230 288 "Bctif35, similar to yeast TIF35, eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3); subunit of the core complex of eIF3; is essential for translation; stimulates resumption of ribosomal scanning during translation reinitiation [Source:SGD;Acc:S000002837]" Bcin07g06240 509 Bcin07g06250 510 "Bccdc36, similar to yeast CDC36, Component of the CCR4-NOT core complex; this complex has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs through deadenylation; basal transcription factor [Source:SGD;Acc:S000002324]" Bcin07g06260 750 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin07g06270 171 Effector(V2)|Effector(V1) Bcin07g06280 1179 "Bcsmc2, similar to yeast SMC2, Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; essential SMC chromosomal ATPase family member that forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for clustering of tRNA genes at the nucleolus [Source:SGD;Acc:S000001927]" Bcin07g06290 463 Molybdenum cofactor sulfurase, C-terminal + MOSC, N-terminal beta barrel + Pyruvate kinase-like, insert domain Bcin07g06300 194 Effector(V2)|Effector(V1) Thioesterase superfamily + HotDog domain Bcin07g06310 467 Transporter "Bcole1, similar to yeast OLE1, Delta(9) fatty acid desaturase; required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria [Source:SGD;Acc:S000003023]" Bcin07g06320 731 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin07g06330 191 Glucose-methanol-choline oxidoreductase, N-terminal + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin07g06340 245 Protease "Bcpup2, similar to yeast PUP2, Alpha 5 subunit of the 20S proteasome; involved in ubiquitin-dependent catabolism; human homolog is subunit zeta [Source:SGD;Acc:S000003485]" Bcin07g06350 913 "Bcspc97, similar to yeast SPC97, Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque [Source:SGD;Acc:S000001215]" Bcin07g06360 622 "Bcmet13, similar to yeast MET13, Major isozyme of methylenetetrahydrofolate reductase; catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway [Source:SGD;Acc:S000003093]" Bcin07g06370 1064 Cys2His2 transcription factor Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin07g06380 95 SignalP-noTM Bcin07g06390 252 "Bcmrpl4, similar to yeast MRPL4, Mitochondrial ribosomal protein of the large subunit; homolog of prokaryotic L29 ribosomal protein; located at the ribosomal tunnel exit [Source:SGD;Acc:S000004431]" Bcin07g06400 471 "Bcgdi1, similar to yeast GDI1, GDP dissociation inhibitor; regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins [Source:SGD;Acc:S000000938]" Bcin07g06410 151 Bcin07g06420 72 Effector(V2) Bcin07g06430 409 Bcin07g06440 545 Transporter Tetracycline resistance protein, TetA/multidrug resistance protein MdtG + Major facilitator superfamily + Major facilitator superfamily domain Bcin07g06450 606 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin07g06460 1061 Bcin07g06470 743 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin07g06480 299 CAZy : CE5PCW hemicellulose//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Cutinase + Alpha/Beta hydrolase fold Bcin07g06490 886 Two pore domain potassium channel + Two pore domain potassium channel domain Bcin07g06500 436 "Bcsrf1, similar to yeast SRF1, Regulator of phospholipase D (Spo14p); interacts with Spo14p and regulates its catalytic activity; capable of buffering the toxicity of C16:0 platelet activating factor, a lipid that accumulates intraneuronally in Alzheimer's patients [Source:SGD;Acc:S000002291]" Bcin07g06510 279 Protein of unknown function DUF2343 Bcin07g06520 598 Protein of unknown function DUF3716 Bcin07g06530 467 Protein of unknown function DUF3716 Bcin07g06540 770 CAZy : GH16FCW Glycoside hydrolase, family 16 + Beta-glucan synthesis-associated, SKN1 + Concanavalin A-like lectin/glucanase domain Bcin07g06550 775 "Bcleu1, similar to yeast LEU1, Isopropylmalate isomerase; catalyzes the second step in the leucine biosynthesis pathway [Source:SGD;Acc:S000002977]" Bcin07g06560 1086 DNA mismatch repair protein family + Histidine kinase-like ATPase, C-terminal domain + DNA mismatch repair protein, C-terminal + Ribosomal protein S5 domain 2-type fold, subgroup + DNA mismatch repair, conserved site + MutL, C-terminal, dimerisation + Ribosomal protein S5 domain 2-type fold + DNA mismatch repair protein Pms1/Pms2 Bcin07g06570 372 GATA zinc finger transcription factor BcareB, GATA zinc finger transcription factor Bcin07g06580 349 "Bckrr1, similar to yeast KRR1, Nucleolar protein required for rRNA synthesis and ribosomal assembly; required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit; essential gene [Source:SGD;Acc:S000000564]" Bcin07g06590 291 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa S1/P1 nuclease + Phospholipase C/P1 nuclease domain Bcin07g06600 530 CAZy : GH132 //SignalP-noTM SUN Bcin07g06610 386 "Bcppm1, similar to yeast PPM1, Carboxyl methyltransferase; methylates the C terminus of the protein phosphatase 2A catalytic subunit (Pph21p or Pph22p), which is important for complex formation with regulatory subunits; required for methionine to inhibit autophagy and promote growth [Source:SGD;Acc:S000002843]" Bcin07g06620 598 Major facilitator superfamily domain + Autophagy-related protein 22-like Bcin07g06630 292 Protein of unknown function DUF3425 Bcin07g06640 404 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin07g06650 776 CAZy : CBM21 Putative phosphatase regulatory subunit Bcin07g06660 319 Bcin07g06670 178 Effector(V1) "Bcaim1, similar to yeast AIM1, Protein involved in mitochondrial function or organization; null mutant displays elevated frequency of mitochondrial genome loss [Source:SGD;Acc:S000000044]" Bcin07g06680 675 Heterokaryon incompatibility Bcin07g06690 252 SGNH hydrolase-type esterase domain Bcin07g06700 488 CAZy : GH1PCW/FCW Glycoside hydrolase, family 1 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin07g06710 747 CAZy : GH95PCW pectin Six-hairpin glycosidase-like + Alpha-L-fucosidase + Glycosyl hydrolase family, N-terminal domain Bcin07g06720 547 Transporter General substrate transporter + Major facilitator superfamily domain Bcin07g06730 286 SM 0 Protein of unknown function DUF3328 Bcin07g06740 83 SignalP-noTM Bcin07g06750 357 Cys2His2 transcription factor BcabaR1, C2H2 transcription factor, positively regulates abscisic acid production (Wang et al., 2018) Bcin07g06760 848 Ubiquitin interacting motif Bcin07g06770 184 SignalP-noTM Bcin07g06780 589 SignalP-noTM//Early secretome Bclcc9, Laccase Bcin07g06790 500 Autophagy-related protein 17 Bcin07g06800 722 yes BcMTF1, mycoparasitic transpcrption factor 1, Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin07g06810 311 Endonuclease/exonuclease/phosphatase Bcin07g06820 209 Bcin07g06830 1039 Cys2His2 transcription factor Bcin07g06840 387 Bcin07g06850 361 Bcin07g06860 282 Bcin07g06870 213 Bcin07g06880 381 Bcin07g06890 332 Bcin07g06900 770 Bcin07g06910 726 "Bcmet30, similar to yeast MET30, F-box protein containing five copies of the WD40 motif; controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus; dissociation of Met30p from SCF complex in response to cadmium stress is regulated by Cdc48p [Source:SGD;Acc:S000001308]" Bcin07g06920 470 Bcin07g06930 374 Bcin07g06940 280 Bcin07g06950 387 SignalP-noTM Inosine/uridine-preferring nucleoside hydrolase domain + Inosine/uridine-preferring nucleoside hydrolase Bcin07g06960 2278 Carboxyl transferase + Biotin/lipoyl attachment + Biotin-binding site + Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain + Carbamoyl-phosphate synthase, large subunit, N-terminal + Biotin carboxylase, C-terminal + Single hybrid motif + Rudiment single hybrid motif + ATP-grasp fold + Acetyl-coenzyme A carboxyltransferase, N-terminal + Acetyl-coenzyme A carboxyltransferase, C-terminal + Biotin carboxylation domain + Acetyl-CoA carboxylase, central domain + ATP-grasp fold, subdomain 1 + ATP-grasp fold, subdomain 2 + Pre-ATP-grasp domain + ClpP/crotonase-like domain Bcin07g06970 616 NUDE protein, C-terminal + NUDE family Bcin07g06980 532 Transporter Amino acid/polyamine transporter I + Amino acid permease, conserved site Bcin07g06990 489 Isochorismatase-like Bcin07g07000 464 Kelch-type beta propeller Bcin07g07010 273 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin07g07020 158 Effector(V1) Bcin07g07030 177 Effector(V2)|Effector(V1) Bcin07g07040 108 Effector(V1) Bcin07g07050 356 SignalP-noTM Bcin07g07060 1448 Bcin07g07070 1747 "Bcssm4, similar to yeast SSM4, Ubiquitin-protein ligase involved in ER-associated protein degradation; located in the ER/nuclear envelope; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation [Source:SGD;Acc:S000001292]" Bcin07g07080 509 SignalP-noTM Bchap2, Phytase Bcin07g07090 693 Lipoxygenase + Lipoxygenase, C-terminal Bcin07g07100 543 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin07g07110 468 Amino acid transporter, transmembrane domain Bcin07g07120 451 Transferase + Chloramphenicol acetyltransferase-like domain Bcin07g07130 515 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin08g00010 522 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin08g00020 163 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin08g00030 223 GNAT domain + Acyl-CoA N-acyltransferase Bcin08g00040 125 SignalP-noTM//Effector(V1) Bcin08g00050 124 Bclcc11, Laccase/ Multicopper oxidase Bcin08g00060 618 Glycoside hydrolase, family 43 + Concanavalin A-like lectin/glucanase domain + Glycosyl hydrolase, five-bladed beta-propellor domain Bcin08g00070 826 CAZy : GT1 UDP-glucuronosyl/UDP-glucosyltransferase + Glycosyltransferase family 28, N-terminal domain Bcin08g00080 363 Heterokaryon incompatibility Bcin08g00090 444 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin08g00100 698 Protein of unknown function DUF3431 Bcin08g00110 303 Protease Epoxide hydrolase-like + Putative lysophospholipase + Alpha/Beta hydrolase fold Bcin08g00120 325 yes Bcaqp8, Aquaporin Bcin08g00130 463 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin08g00140 514 Histidine phosphatase superfamily Bcin08g00150 395 SignalP-noTM//Early secretome Phospholipase C, phosphatidylinositol-specific , X domain + PLC-like phosphodiesterase, TIM beta/alpha-barrel domain Bcin08g00160 683 yes Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin08g00170 715 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin08g00180 202 Effector(V1) Bcin08g00190 320 Phosphoribosyltransferase domain + Phosphoribosyltransferase-like Bcin08g00200 178 Bcin08g00210 463 Bacteriophage T5, Orf172 DNA-binding Bcin08g00220 693 Bcin08g00230 603 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site Bcin08g00240 703 Magnesium transporter NIPA Bcin08g00250 366 Bcin08g00260 648 Bcin08g00270 565 Transporter "Bcstl1, similar to yeast STL1, Glycerol proton symporter of the plasma membrane; subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock [Source:SGD;Acc:S000002944]" Bcin08g00280 475 Protease//SignalP-noTM//Early secretome Peptidase S10, serine carboxypeptidase + Peptidase S10, serine carboxypeptidase, active site + Alpha/Beta hydrolase fold + Serine carboxypeptidases, histidine active site Bcin08g00290 2129 SM cluster PKS19 (KE)//Protease Bcpks19, Polyketide synthase Bcin08g00300 250 Bcgst11, Glutathione S-transferase Bcin08g00310 369 Bcin08g00320 520 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin08g00330 534 Bcin08g00340 531 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin08g00350 507 Bcin08g00360 429 Bcin08g00370 444 BAR domain + Arfaptin homology (AH) domain/BAR domain Bcin08g00380 386 CRC domain + Tesmin/TSO1-like CXC domain Bcin08g00390 346 Bcin08g00400 174 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Bcin08g00410 257 F-box domain Bcin08g00420 443 Ferredoxin reductase-type FAD-binding domain Bcin08g00430 241 Bcin08g00440 1003 "Bcnnf2, similar to yeast NNF2, Protein that exhibits physical and genetic interactions with Rpb8p; Rpb8p is a subunit of RNA polymerases I, II, and III; computational analysis of large-scale protein-protein interaction data suggests a role in chromosome segregation [Source:SGD;Acc:S000003321]" Bcin08g00450 763 Bcin08g00460 502 "Bcpri2, similar to yeast PRI2, Subunit of DNA primase; DNA primase is required for DNA synthesis and double-strand break repair [Source:SGD;Acc:S000001528]" Bcin08g00470 751 Bcin08g00480 167 Effector(V2)|Effector(V1) Bcin08g00490 281 HotDog domain Bcin08g00500 455 Bcin08g00510 759 Leucine-rich repeat + Leucine-rich repeat, typical subtype + Endonuclease/exonuclease/phosphatase + Leucine-rich repeat domain, L domain-like Bcin08g00520 615 S-adenosyl-L-methionine-dependent methyltransferase Bcin08g00530 88 Bcin08g00540 1049 Protease "Bcpff1, similar to yeast PFF1, Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to the M28 family of metalloproteases; has a lumenal-facing protease domain; proposed role in vacuole physiology [Source:SGD;Acc:S000000278]" Bcin08g00550 945 yes Signaling pathway Bcpde2, CAMP phosphodiesterase Bcin08g00560 525 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin08g00570 172 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin08g00580 651 CAZy : GT90 Lipopolysaccharide-modifying protein Bcin08g00590 298 "Bcmrpl10, similar to yeast MRPL10, Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels [Source:SGD;Acc:S000005228]" Bcin08g00600 730 "Bcmvp1, similar to yeast MVP1, Protein required for sorting proteins to the vacuole; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole; participates in transcription initiation and/or early elongation of specific genes; interacts with foot domain of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004606]" Bcin08g00610 271 "Bcdcn1, similar to yeast DCN1, Scaffold-type E3 ligase; required for cullin neddylation and ubiquitin ligase activation; contains a ubiquitin-binding domain (UBA) for ubiquitin and Nedd8 (Rub1p) interaction and a PONY domain involved in cullin binding and neddylation [Source:SGD;Acc:S000004118]" Bcin08g00620 121 Effector(V2)|Effector(V1) "Bcmrp17, similar to yeast MRP17, Mitochondrial ribosomal protein of the small subunit; MRP17 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator [Source:SGD;Acc:S000001486]" Bcin08g00630 489 "Bcrrb1, similar to yeast RRB1, Nuclear protein involved in early steps of ribosome biogenesis; physically interacts with the ribosomal protein Rpl3p; essential gene [Source:SGD;Acc:S000004738]" Bcin08g00640 315 Bcin08g00650 179 Effector(V1) Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase Bcin08g00660 476 "Bcprp19, similar to yeast PRP19, Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiquitin ligases, and a WD40 domain; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003959]" Bcin08g00670 441 Zinc finger, RING/FYVE/PHD-type Bcin08g00680 1246 Cys2His2 transcription factor + Fungal_trans Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin08g00690 301 "Bclas1, similar to yeast LAS1, Protein required for pre-rRNA processing at both ends of ITS2; functions with Grc3p in a conserved mechanism to modulate rRNA processing and ribosome biogenesis; may coordinate the action of the Rat1p-Rai1p exoRNAse; required for the G1/S cell cycle transition; human ortholog is Las1L; mutants require the SSD1-v allele for viability [Source:SGD;Acc:S000001771]" Bcin08g00700 399 Bcin08g00710 576 NAD kinase + NAD kinase/diacylglycerol kinase-like domain + Inorganic polyphosphate/ATP-NAD kinase, domain 1 + ATP-NAD kinase, PpnK-type, all-beta Bcin08g00720 399 Protease//SignalP-noTM//Early secretome Bcap14, Aspartic proteinase Bcin08g00730 211 Bcin08g00740 537 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin08g00750 158 Bcin08g00760 56 Effector(V2)|Effector(V1) Ribosomal protein S14 + Ribosomal protein S14, conserved site Bcin08g00770 105 Apc13p Bcin08g00780 225 Effector(V2)|Effector(V1) "Bctrs31, similar to yeast TRS31, Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII) [Source:SGD;Acc:S000002880]" Bcin08g00790 383 CRAL-TRIO domain + CRAL/TRIO, N-terminal domain Bcin08g00800 670 "Bcpol12, similar to yeast POL12, B subunit of DNA polymerase alpha-primase complex; required for initiation of DNA replication during mitotic and premeiotic DNA synthesis; also functions in telomere capping and length regulation [Source:SGD;Acc:S000000131]" Bcin08g00810 477 "Bcgcd2, similar to yeast GCD2, Delta subunit of the translation initiation factor eIF2B; the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression [Source:SGD;Acc:S000003315]" Bcin08g00820 85 Bcin08g00830 774 Bcin08g00840 102 Bcin08g00850 550 yes Signaling pathway BcPtpB, Protein Tyrosine Phosphatase Bcin08g00860 724 Protease "Bcubp1, similar to yeast UBP1, Ubiquitin-specific protease; removes ubiquitin from ubiquitinated proteins; cleaves at the C terminus of ubiquitin fusions irrespective of their size; capable of cleaving polyubiquitin chains [Source:SGD;Acc:S000002280]" Bcin08g00870 177 Effector(V1) Ribosome biogenesis protein Alb1 Bcin08g00880 396 Micro-fibrillar-associated protein 1, C-terminal Bcin08g00890 654 CAZy : GH51PCW hemicellulose or pectin//SignalP-noTM//Early secretome Alpha-L-arabinofuranosidase, C-terminal + Glycoside hydrolase superfamily Bcin08g00900 313 PQ-loop repeat Bcin08g00910 303 CAZy : GH17FCW //SignalP-noTM "Bcbgl2, similar to yeast BGL2, Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall [Source:SGD;Acc:S000003514]" Bcin08g00920 2151 Bcin08g00930 302 yes Bccpdh, dehyfrogenase for capsidiol detoxification Bcin08g00940 96 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Extracellular membrane protein, CFEM domain Bcin08g00950 303 CAZy : CE16PCW hemicellulose//SignalP-noTM SGNH hydrolase-type esterase domain Bcin08g00960 359 Bcin08g00970 531 Bcin08g00980 156 Effector(V1) Bcin08g00990 82 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin08g01000 524 CAZy : GT1 UDP-glucuronosyl/UDP-glucosyltransferase Bcin08g01010 127 Effector(V2)|Effector(V1) Bcin08g01020 673 Protease//SignalP-noTM Peptidase S8/S53 domain + Proteinase inhibitor, propeptide + Peptidase S53, propeptide + Sedolisin domain Bcin08g01030 1060 "Bctae2, similar to yeast TAE2, Component of the ribosome quality control complex (RQC); RQC (Rqc1p-Rkr1p-Tae2p-Cdc48p-Npl4p-Ufd1p) is a ribosome-bound complex required for the degradation of polypeptides arising from stalled translation involved in protein translation; monitors translation stress and signals this to Hsf1p; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm [Source:SGD;Acc:S000005930]" Bcin08g01040 984 Bcin08g01050 752 Heterokaryon incompatibility Bcin08g01060 478 FAD linked oxidase, N-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin08g01070 564 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin08g01080 299 Bcin08g01090 352 Ankyrin repeat + Ankyrin repeat-containing domain Bcin08g01100 164 Effector(V2) Bcin08g01110 194 yes Effector(V2)|Effector(V1)//Early secretome Bchex, Protein of the Woronin body Bcin08g01120 505 Protease "Bclap3, similar to yeast LAP3, Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH [Source:SGD;Acc:S000005183]" Bcin08g01130 648 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin08g01140 172 SignalP-noTM Cell wall galactomannoprotein Bcin08g01150 1149 "Bcmdr1, similar to yeast MDR1, Cytoplasmic GTPase-activating protein; activates Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function [Source:SGD;Acc:S000003332]" Bcin08g01160 1554 Bcin08g01170 230 Bcin08g01180 585 Protein of unknown function DUF3468 Bcin08g01190 373 Bcin08g01200 399 Alkylated DNA repair protein AlkB + Alpha-ketoglutarate-dependent dioxygenase AlkB-like Bcin08g01210 299 RTA-like protein Bcin08g01220 84 Effector(V2)|Effector(V1) Bcin08g01230 604 Cys2His2 transcription factor Zinc finger, C2H2 Bcin08g01240 459 Bcin08g01250 323 Bcin08g01260 517 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin08g01270 756 Bcin08g01280 619 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain Bcin08g01290 351 Bcin08g01300 478 Bcin08g01310 494 Protein of unknown function DUF1308 Bcin08g01320 271 DnaJ domain Bcin08g01330 411 "Bciba57, similar to yeast IBA57, Protein involved in incorporating iron-sulfur clusters into proteins; mitochondrial matrix protein; involved in the incorporation of iron-sulfur clusters into mitochondrial aconitase-type proteins; activates the radical-SAM family members Bio2p and Lip5p; interacts with Ccr4p in the two-hybrid system [Source:SGD;Acc:S000003883]" Bcin08g01340 943 "Bcdcp2, similar to yeast DCP2, Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex; removes the 5' cap structure from mRNAs prior to their degradation; also enters the nucleus and positively regulates transcription initiation; nudix hydrolase family member; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000005062]" Bcin08g01350 327 Protein of unknown function DUF4112 Bcin08g01360 407 Ribonucleotide reductase small subunit + Ferritin-like superfamily + Ribonucleotide reductase-related + Ribonucleotide reductase small subunit, acitve site Bcin08g01370 170 Bcin08g01380 509 Bcin08g01390 883 Bcin08g01400 767 P-loop containing nucleoside triphosphate hydrolase Bcin08g01410 290 Signaling pathway BcphnA, Phosducin-like protein (subgroup I) Bcin08g01420 358 yes Signaling pathway Bcgb1, Heterotrimeric G beta subunit Bcin08g01430 343 Adenosine/AMP deaminase domain + Metal-dependent hydrolase Bcin08g01440 375 Amidohydrolase 1 + Metal-dependent hydrolase Bcin08g01450 347 Oxoglutarate/iron-dependent dioxygenase + Non-haem dioxygenase N-terminal domain + Isopenicillin N synthase-like Bcin08g01460 1073 "Bcgcv2, similar to yeast GCV2, P subunit of the mitochondrial glycine decarboxylase complex; glycine decarboxylase is required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of 5,10-methylene-THF in the cytoplasm [Source:SGD;Acc:S000004801]" Bcin08g01470 249 GNAT domain + Acyl-CoA N-acyltransferase Bcin08g01480 424 "Bcnup57, similar to yeast NUP57, FG-nucleoporin component of central core of the nuclear pore complex; contributes directly to nucleocytoplasmic transport and maintenance of the nuclear pore complex (NPC) permeability barrier; found in stable complex with Nic96p and two other FG-nucleoproteins (Nsp1p and Nup49p) [Source:SGD;Acc:S000003351]" Bcin08g01490 156 Effector(V2)|Effector(V1) CHCH + NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8 Bcin08g01500 1025 Dynamin superfamily + P-loop containing nucleoside triphosphate hydrolase Bcin08g01510 446 "Bczuo1, similar to yeast ZUO1, Ribosome-associated chaperone; zuotin functions in ribosome biogenesis and, in partnership with Ssz1p and SSb1/2, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p [Source:SGD;Acc:S000003517]" Bcin08g01520 111 Effector(V2)|Effector(V1) "Bcmzm1, similar to yeast MZM1, Protein required for assembly of the cytochrome bc(1) complex; acts as a chaperone for Rip1p and facilitates its insertion into the complex at a late stage of assembly; localized to the mitochondrial matrix; null mutant exhibits a respiratory growth defect and reduced mitochondrial zinc levels, which is characteristic of mutations affecting bc(1) complex assembly; member of the LYR protein family; human LYRM7 is a functional ortholog [Source:SGD;Acc:S000002901]" Bcin08g01530 382 "Bcecm2, similar to yeast ECM2, Pre-mRNA splicing factor; facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p [Source:SGD;Acc:S000000269]" Bcin08g01540 378 Sterol methyltransferase C-terminal + S-adenosyl-L-methionine-dependent methyltransferase + SAM-dependent methyltransferase SMT-type Bcin08g01550 164 Effector(V2)|Effector(V1) Domain of unknown function DUF1993 + DinB/YfiT-like putative metal-dependent hydrolase Bcin08g01560 601 Bcin08g01570 942 Domain of unknown function DUF2439 Bcin08g01580 237 CAZy : CE5PCW hemicellulose//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Cutinase + Alpha/Beta hydrolase fold Bcin08g01590 497 "Bcrvs161, similar to yeast RVS161, Amphiphysin-like lipid raft protein; interacts with Rvs167p and regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress [Source:SGD;Acc:S000000602]" Bcin08g01600 530 Bcin08g01610 316 Bcin08g01620 170 Bcin08g01630 72 Effector(V2)|Effector(V1) Bcin08g01640 725 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin08g01650 669 Cys2His2 transcription factor "Bcvms1, similar to yeast VMS1, Component of a Cdc48p-complex involved in protein quality control; exhibits cytosolic and ER-membrane localization, with Cdc48p, during normal growth, and contributes to ER-associated degradation (ERAD) of specific substrates at a step after their ubiquitination; forms a mitochondrially-associated complex with Cdc48p and Npl4p under oxidative stress that is required for ubiquitin-mediated mitochondria-associated protein degradation (MAD); conserved in C. elegans and humans [Source:SGD;Acc:S000002456]" Bcin08g01660 749 Bactericidal permeability-increasing protein, alpha/beta domain Bcin08g01670 111 Effector(V1) YCII-related + Dimeric alpha-beta barrel Bcin08g01680 109 Effector(V2)|Effector(V1) Bcin08g01690 670 yes Zn2/Cys6 transcription factor Bcltf5, Light-responsive Zn2/Cys6 transcription factor Bcin08g01700 208 NUDIX hydrolase domain + NUDIX hydrolase domain-like + NUDIX hydrolase, conserved site + NUDIX hydrolase Bcin08g01710 1243 PAP/25A-associated + Nucleotidyl transferase domain Bcin08g01720 276 Bcin08g01730 413 Bcin08g01740 853 yes Signaling pathway Brrg1, Response regulator protein, core element of two-component signaling pathway Bcin08g01750 150 Effector(V2) ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin08g01760 501 Bcin08g01770 303 Taurine catabolism dioxygenase TauD/TfdA Bcin08g01780 455 Major facilitator superfamily + Major facilitator superfamily domain Bcin08g01790 463 Bcin08g01800 441 Ornithine/DAP/Arg decarboxylase + Ornithine decarboxylase + Alanine racemase/group IV decarboxylase, C-terminal + Orn/DAP/Arg decarboxylase 2, C-terminal + Orn/DAP/Arg decarboxylase 2, N-terminal + Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site + PLP-binding barrel Bcin08g01810 895 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin08g01820 465 Bcin08g01830 484 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin08g01840 667 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Peptidase A2A, retrovirus, catalytic + Transcription factor domain, fungi Bcin08g01850 280 Protein of unknown function DUF1445 Bcin08g01860 738 Nucleotide-diphospho-sugar transferases Bcin08g01870 724 yes Bcaqp4, Aquaporin Bcin08g01880 253 Effector(V2) Bcprx5, Peroxiredoxin (AhpC-TSA_2 family) Bcin08g01890 394 Bcin08g01900 322 CAZy : GH18FCW //SignalP-noTM Glycoside hydrolase, family 18, catalytic domain + Glycoside hydrolase, chitinase active site + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin08g01910 280 "Bcysa1, similar to yeast YSA1, Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; shown to metabolize O-acetyl-ADP-ribose to AMP and acetylated ribose 5'-phosphate [Source:SGD;Acc:S000000315]" Bcin08g01920 272 NUDIX hydrolase domain + NUDIX hydrolase domain-like Bcin08g01930 553 Protease//SignalP-noTM Aspartic peptidase domain + Peptidase family A1 domain Bcin08g01940 186 Bcin08g01950 107 Effector(V2)|Effector(V1) Bcin08g01960 336 RTA-like protein Bcin08g01970 659 Bcin08g01980 483 Bcdao10, D-amino acid oxidase Bcin08g01990 554 Transporter Amino acid/polyamine transporter I + Amino acid permease/ SLC12A domain Bcin08g02000 241 HAD-like domain Bcin08g02010 1116 Bcin08g02020 831 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin08g02030 419 SignalP-noTM Bcin08g02040 309 Bcin08g02050 472 Bcin08g02060 117 Effector(V2)|Effector(V1) Ethanolamine utilisation EutQ + RmlC-like cupin domain + RmlC-like jelly roll fold Bcin08g02070 488 Protease Creatinase, N-terminal + Peptidase M24, structural domain + Creatinase/Aminopeptidase P, N-terminal + Creatinase/Aminopeptidase P/Spt16, N-terminal Bcin08g02080 109 Effector(V1)//Early secretome Antibiotic biosynthesis monooxygenase-like domain + Dimeric alpha-beta barrel Bcin08g02090 555 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin08g02100 153 Effector(V2)|Effector(V1) Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase Bcin08g02110 658 CAZy : CBM1,GH5PCW/FCW //SignalP-noTM Cellulose-binding domain, fungal + Glycoside hydrolase, family 5 + Carbohydrate binding X2 domain + Glycoside hydrolase, catalytic domain + Immunoglobulin-like fold + Immunoglobulin E-set + Glycoside hydrolase superfamily Bcin08g02120 666 CAZy : GH27,CBM35PCW hemicellulose//SignalP-noTM//Early secretome Glycoside hydrolase, family 27 + Glycosyl hydrolase, family 13, all-beta + Aldolase-type TIM barrel + Glycoside hydrolase superfamily Bcin08g02130 561 CAZy : GH13Energy //SignalP-noTM Glycosyl hydrolase, family 13, catalytic domain + Glycosyl hydrolase, family 13, all-beta + Glycoside hydrolase, catalytic domain + Alpha-amylase, domain of unknown function DUF1966, C-terminal + Glycoside hydrolase superfamily Bcin08g02140 2467 CAZy : GH13,GT5Energy //SignalP-noTM Glycosyl transferase, family 1 + Glycosyl hydrolase, family 13, catalytic domain + Starch synthase, catalytic domain + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin08g02150 166 SignalP-noTM Bcin08g02160 195 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin08g02170 316 SignalP-TM Mid2 domain Bcin08g02180 204 Effector(V2) Bcin08g02190 408 3-beta hydroxysteroid dehydrogenase/isomerase + NAD(P)-binding domain Bcin08g02200 360 Bcin08g02210 501 Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin08g02220 1359 Bcrprd, Bcrdr2, RNA-dependent RNA polymerase Bcin08g02230 2992 FMP27, domain of unknown function DUF2405 + FMP27, SW domain + FMP27, N-terminal + FMP27, GFWDK domain + FMP27, C-terminal + FMP27, WPPW domain Bcin08g02240 506 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 Bcin08g02250 621 Protein kinase domain + Protein kinase-like domain Bcin08g02260 463 Bcin08g02270 306 Peroxisomal biogenesis factor 11 Bcin08g02280 407 Bcin08g02290 281 Mpv17/PMP22 Bcin08g02300 484 Bcin08g02310 431 Pleckstrin homology domain + Pleckstrin homology-like domain Bcin08g02320 118 Effector(V1) Bcin08g02330 1077 "Bcria1, similar to yeast RIA1, Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis; with Sdo1p, a guanine nucleotide exchange factor (GEF), promotes release of Tif6p from 60S ribosomal subunits in the cytoplasm so that they can assemble with 40S subunits to generate mature ribosomes; required for quality control check of newly made large ribosomal subunits before they are released into the pool of translating ribosomes [Source:SGD;Acc:S000005107]" Bcin08g02340 202 SM cluster STC2//Effector(V1) HAD-like domain Bcin08g02350 329 yes SM cluster STC2 (KE) Bcstc2, Sesquiterpen cyclase Bcin08g02360 895 SignalP-noTM "Bctul1, similar to yeast TUL1, Subunit of the DSC ubiquitin ligase complex; golgi-localized RING-finger ubiquitin ligase (E3) involved in sorting polar transmembrane domain containing membrane proteins to multivesicular bodies for delivery to the vacuole; proposed involvement in the quality control of misfolded TMD containing proteins; ortholog of fission yeast dsc1 [Source:SGD;Acc:S000001517]" Bcin08g02370 89 Heat shock factor binding 1 Bcin08g02380 366 SignalP-noTM Disulphide isomerase + Endoplasmic reticulum, protein ERp29, C-terminal + Thioredoxin-like fold + Thioredoxin domain + Thioredoxin, conserved site Bcin08g02390 544 Protease//SignalP-noTM//Early secretome Peptidase S28 + Alpha/Beta hydrolase fold Bcin08g02400 483 Protease//Effector(V2)|Effector(V1) Arginine biosynthesis protein ArgJ + ArgJ-like domain Bcin08g02410 565 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin08g02420 560 Putative fluoride ion transporter CrcB Bcin08g02430 234 Uracil phosphoribosyl transferase + Phosphoribosyltransferase-like Bcin08g02440 113 Effector(V1) Bcin08g02450 222 Effector(V1) GDPGTP exchange factor Sec2p Bcin08g02460 247 Effector(V2) Bcin08g02470 474 Protease//SignalP& 0TM& >3cys& Len<300aa Carboxylesterase, type B + Alpha/Beta hydrolase fold Bcin08g02480 598 Protease Cholinesterase + Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin08g02490 131 "Bcrpl32, similar to yeast RPL32, Ribosomal 60S subunit protein L32; overexpression disrupts telomeric silencing; homologous to mammalian ribosomal protein L32, no bacterial homolog [Source:SGD;Acc:S000000188]" Bcin08g02500 428 "Bcxdj1, similar to yeast XDJ1, Chaperone with a role in facilitating mitochondrial protein import; ascomycete-specific member of the DnaJ-like family, closely related to Ydj1p; predicted to be C-terminally prenylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000004080]" Bcin08g02510 612 "Bcmse1, similar to yeast MSE1, Mitochondrial glutamyl-tRNA synthetase; predicted to be palmitoylated [Source:SGD;Acc:S000005393]" Bcin08g02520 353 Protease "Bcrri1, similar to yeast RRI1, Catalytic subunit of the COP9 signalosome (CSN) complex; acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling [Source:SGD;Acc:S000002375]" Bcin08g02530 777 "Bcase1, similar to yeast ASE1, Mitotic spindle midzone-localized microtubule bundling protein; microtubule-associated protein (MAP) family member; required for spindle elongation and stabilization; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate; relative distribution to microtubules decreases upon DNA replication stress [Source:SGD;Acc:S000005584]" Bcin08g02540 1006 "Bcdnl4, similar to yeast DNL4, DNA ligase required for nonhomologous end-joining (NHEJ); forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth [Source:SGD;Acc:S000005531]" Bcin08g02550 312 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin08g02560 428 Effector(V1) GroES (chaperonin 10)-like + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin08g02570 214 Effector(V2)|Effector(V1) Polyketide synthase, ketoreductase domain + NAD(P)-binding domain Bcin08g02580 495 Bcin08g02590 885 EPS15 homology (EH) + EF-hand domain pair Bcin08g02600 711 "Bcedc3, similar to yeast EDC3, Non-essential conserved protein with a role in mRNA decapping; specifically affects the function of the decapping enzyme Dcp1p; mediates decay of the RPS28B mRNA via binding to both Rps28Bp (or Rps28Ap) and the RPS28B mRNA; mediates decay of the YRA1 mRNA by a different, translation-independent mechanism; localizes to cytoplasmic mRNA processing bodies; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000000741]" Bcin08g02610 914 Zinc finger, CCHC-type + AAA+ ATPase domain + DNA helicase + DNA helicase Pif1 like + P-loop containing nucleoside triphosphate hydrolase Bcin08g02620 504 "Bcpub1, similar to yeast PUB1, Poly (A)+ RNA-binding protein; abundant mRNP-component protein that binds mRNA and is required for stability of many mRNAs; component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004961]" Bcin08g02630 368 Bcin08g02640 195 Effector(V1) Bcin08g02650 281 Bcin08g02660 532 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin08g02670 828 Domain of unknown function DUF255 + Six-hairpin glycosidase-like + Thioredoxin-like fold + Six-hairpin glycosidase + Spermatogenesis-associated protein 20 Bcin08g02680 320 SignalP-noTM Cysteine-rich secretory protein, allergen V5/Tpx-1-related + CAP domain Bcin08g02690 1470 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase + Alpha-factor-transporting ATPase Ste6 Bcin08g02700 312 Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin08g02710 220 Bzip transcription factor Basic-leucine zipper domain Bcin08g02720 126 Effector(V2)|Effector(V1) "Bcpet191, similar to yeast PET191, Protein required for assembly of cytochrome c oxidase; exists as an oligomer; described as both an integral mitochondrial inner membrane protein facing the intermembrane space (IMS) and as a soluble IMS protein; contains a twin Cx9C motif; imported into the IMS via the MIA import machinery [Source:SGD;Acc:S000003795]" Bcin08g02730 737 Protease "Bctgl1, similar to yeast TGL1, Steryl ester hydrolase; one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes [Source:SGD;Acc:S000001623]" Bcin08g02740 478 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin08g02750 485 TRAM/LAG1/CLN8 homology domain + TRAM1-like protein + Ceramide synthase component Lag1/Lac1 Bcin08g02760 278 "Bcbxi1, similar to yeast BXI1, Protein involved in apoptosis; variously described as containing a BCL-2 homology (BH3) domain or as a member of the BAX inhibitor family; reported to promote apoptosis under some conditions and to inhibit it in others; localizes to ER and vacuole; may link the unfolded protein response to apoptosis via regulation of calcium-mediated signaling; translocates to mitochondria under apoptosis-inducing conditions in a process involving Mir1p and Cor1p [Source:SGD;Acc:S000005249]" Bcin08g02770 385 Septin + P-loop containing nucleoside triphosphate hydrolase + Septin-type guanine nucleotide-binding (G) domain Bcin08g02780 390 "Bchsv2, similar to yeast HSV2, Phosphatidylinositol 3,5-bisphosphate-binding protein; plays a role in micronucleophagy; belongs to the PROPPIN family of proteins; predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization [Source:SGD;Acc:S000003455]" Bcin08g02790 325 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin08g02800 521 Dynein 1 light intermediate chain + Dynein family light intermediate chain Bcin08g02810 255 Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin08g02820 423 "Bctda3, similar to yeast TDA3, Putative oxidoreductase involved in late endosome to Golgi transport; physical and genetical interactions with Btn2p; null mutant is viable, has extended S phase, and sensitive to expression of top1-T722A allele; similar to human FOXRED1 [Source:SGD;Acc:S000001051]" Bcin08g02830 78 Effector(V1) Bcin08g02840 474 SignalP-noTM "Bcwbp1, similar to yeast WBP1, Beta subunit of the oligosaccharyl transferase glycoprotein complex; required for N-linked glycosylation of proteins in the endoplasmic reticulum [Source:SGD;Acc:S000000728]" Bcin08g02850 373 Bcin08g02860 524 Protease Alpha/beta hydrolase fold-1 + Homoserine acetyltransferase + Alpha/Beta hydrolase fold Bcin08g02870 421 Solute carrier family 35 member SLC35F1/F2/F6 Bcin08g02880 316 SWIRM domain + Homeodomain-like Bcin08g02890 603 F-box domain + Quinonprotein alcohol dehydrogenase-like superfamily + WD40/YVTN repeat-like-containing domain Bcin08g02900 369 Peroxisome membrane protein, Pex16 Bcin08g02910 545 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin08g02920 207 Effector(V2)|Effector(V1) "Bcrsr1, similar to yeast RSR1, GTP-binding protein of the Ras superfamily; required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases [Source:SGD;Acc:S000003384]" Bcin08g02930 438 Lipopolysaccharide-modifying protein Bcin08g02940 510 Protein of unknown function DUF1752, fungi Bcin08g02950 353 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin08g02960 378 SignalP-noTM Bcin08g02970 346 yes CAZy : CE8PCW pectin//SignalP-noTM//Early secretome Bcpme1, Pectin methyl esterase Bcin08g02980 2639 "Bcbph1, similar to yeast BPH1, Protein homologous to Chediak-Higashi syndrome and Beige proteins; both of which are implicated in disease syndromes in human and mouse, respectively, due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting [Source:SGD;Acc:S000000628]" Bcin08g02990 521 yes Protease//SignalP-noTM//Early secretome Bcser2, Subtilisin-like protease Bcin08g03000 1189 Bcin08g03010 355 Bcin08g03020 386 Domain of unknown function DUF2296 Bcin08g03030 1260 "Bcimh1, similar to yeast IMH1, Protein involved in vesicular transport; mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi [Source:SGD;Acc:S000004300]" Bcin08g03040 407 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin08g03050 574 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin08g03060 458 Brl1/Brr6 domain Bcin08g03070 460 "Bcspn1, similar to yeast SPN1, Protein involved in RNA polymerase II transcription; is constitutively recruited to the CYC1 promoter and is required for recruitment of chromatin remodeling factors for the expression of CYC1 gene; interacts genetically or physically with RNAP II, TBP, TFIIS, and chromatin remodelling factors; central domain highly conserved throughout eukaryotes; mutations confer an Spt- phenotype [Source:SGD;Acc:S000006337]" Bcin08g03080 423 Helix-loop-helix (HLH) transcription factor Myc-type, basic helix-loop-helix (bHLH) domain Bcin08g03090 198 Effector(V2)|Effector(V1) "Bcdid2, similar to yeast DID2, Class E protein of the vacuolar protein-sorting (Vps) pathway; binds Vps4p and directs it to dissociate ESCRT-III complexes; forms a functional and physical complex with Ist1p; human ortholog may be altered in breast tumors [Source:SGD;Acc:S000006435]" Bcin08g03100 181 Effector(V1) Protein of unknown function DUF427 Bcin08g03110 933 SignalP-noTM CND17, CalciNeurine-Dependant (CND) gene Bcin08g03120 866 Tetratricopeptide-like helical domain + DNA/RNA-binding domain, Est1-type Bcin08g03130 823 Tetrapeptide transporter, OPT1/isp4 + Oligopeptide transporter, OPT superfamily Bcin08g03140 209 Effector(V2)|Effector(V1) "Bccsl4, similar to yeast CSL4, Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain an S1 RNA binding domain; has similarity to human hCsl4p (EXOSC1) [Source:SGD;Acc:S000005176]" Bcin08g03150 590 Dak kinase + DhaL domain + Dihydroxyacetone kinase Bcin08g03160 118 Effector(V2)|Effector(V1) "Bcsmd2, similar to yeast SMD2, Core Sm protein Sm D2; part of heteroheptameric complex (with Smb1p, Smd1p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D2 [Source:SGD;Acc:S000004265]" Bcin08g03170 525 "Bcehd3, similar to yeast EHD3, 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis [Source:SGD;Acc:S000002443]" Bcin08g03180 1215 GATA zinc finger transcription factor Zinc finger, NHR/GATA-type Bcin08g03190 108 Effector(V2)|Effector(V1) Nucleic acid-binding, OB-fold + Replication factor A protein 3 Bcin08g03200 293 "Bcyml6, similar to yeast YML6, Mitochondrial ribosomal protein of the large subunit; has similarity to E. coli L4 ribosomal protein and human mitoribosomal MRP-L4 protein; essential for viability, unlike most other mitoribosomal proteins [Source:SGD;Acc:S000004487]" Bcin08g03210 425 Protease "Bcmrpl35, similar to yeast MRPL35, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000002730]" Bcin08g03220 572 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin08g03230 153 Effector(V1) NAD(P)-binding domain Bcin08g03240 291 Bcin08g03250 1350 Rho GTPase-activating protein domain + Rho GTPase activation protein Bcin08g03260 383 "Bcsnf4, similar to yeast SNF4, Activating gamma subunit of the AMP-activated Snf1p kinase complex; additional subunits of the complex are Snf1p and a Sip1p/Sip2p/Gal83p family member; activates glucose-repressed genes, represses glucose-induced genes; role in sporulation, and peroxisome biogenesis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003083]" Bcin08g03270 559 "Bcvac8, similar to yeast VAC8, Phosphorylated and palmitoylated vacuolar membrane protein; interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions [Source:SGD;Acc:S000000739]" Bcin08g03280 186 Protease//Effector(V2)|Effector(V1) "Bcimp1, similar to yeast IMP1, Catalytic subunit of mitochondrial inner membrane peptidase complex; required for maturation of mitochondrial proteins of the intermembrane space; complex contains two catalytic subunits (Imp1p and Imp2p that differ in substrate specificty) and Som1p [Source:SGD;Acc:S000004758]" Bcin08g03290 267 Translation initiation factor 3 + Translation initiation factor 3, C-terminal Bcin08g03300 355 Bcin08g03310 165 Bcin08g03320 257 SignalP-noTM Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Bcin08g03330 542 Bcin08g03340 390 Bcin08g03350 164 Effector(V2)|Effector(V1) Bcin08g03360 791 Cullin, N-terminal + Winged helix-turn-helix DNA-binding domain + Cullin, conserved site + Cullin homology + Cullin repeat-like-containing domain + Cullin protein, neddylation domain Bcin08g03370 1687 "Bcnup192, similar to yeast NUP192, Essential subunit of the inner ring of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport; homologous to human NUP205 [Source:SGD;Acc:S000003576]" Bcin08g03380 2929 Phosphatidylinositol 3-/4-kinase, catalytic domain + PIK-related kinase, FAT + PIK-related kinase, FATC + Protein kinase-like domain + PIK-related kinase + ATM + Armadillo-type fold + Phosphatidylinositol 3/4-kinase, conserved site + Telomere-length maintenance and DNA damage repair Bcin08g03390 287 RTA-like protein Bcin08g03400 90 Effector(V1) Bcin08g03410 542 SignalP-noTM Bcin08g03420 505 UBA/THIF-type NAD/FAD binding fold + NAD(P)-binding domain Bcin08g03430 168 Effector(V2)|Effector(V1) Glyoxalase/fosfomycin resistance/dioxygenase domain + Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Bcin08g03440 854 Bcin08g03450 399 RNA 3'-terminal phosphate cyclase + RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta + RNA 3'-terminal phosphate cyclase type 1 + RNA 3'-terminal phosphate cyclase domain Bcin08g03460 254 Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin08g03470 974 SignalP-noTM "Bcemc1, similar to yeast EMC1, Member of conserved endoplasmic reticulum membrane complex; involved in efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; interacts with Gal80p; homologous to worm H17B01.4/EMC-1, fly CG2943, and human KIAA0090 [Source:SGD;Acc:S000000550]" Bcin08g03480 849 OTT_1508-like deaminase Bcin08g03490 471 "Bcldb19, similar to yeast LDB19, Alpha-arrestin involved in ubiquitin-dependent endocytosis; regulates endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its targets; involved in the basal internalization and turnover of alpha-factor receptor Ste2p; recruits ubiquitin ligase Rsp5p to Ste2p via its 2 PPXY motifs; inhibited by Npr1p-mediated phosphorylation, which affects translocation between the cytosol and the plasma membrane [Source:SGD;Acc:S000005849]" Bcin08g03500 1142 SNF2-related + Helicase, C-terminal + Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Helicase superfamily 1/2, ATP-binding domain + HIRAN domain + Zinc finger, C3HC4 RING-type + P-loop containing nucleoside triphosphate hydrolase Bcin08g03510 387 Squalene/phytoene synthase + Isoprenoid synthase domain Bcin08g03520 574 "Bcpho8, similar to yeast PHO8, Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN [Source:SGD;Acc:S000002889]" Bcin08g03530 114 Ribosomal protein L34Ae + Ribosomal protein L34e, conserved site Bcin08g03540 3201 Protease "Bcprp8, similar to yeast PRP8, Component of U4/U6-U5 snRNP complex; involved in second catalytic step of splicing; participates in spliceosomal assembly through its interaction with U1 snRNA; largest and most evolutionarily conserved protein of the spliceosome; mutations in its human ortholog, PRPF8, cause Retinitis pigmentosa and missplicing in Myelodysplastic syndrome. [Source:SGD;Acc:S000001208]" Bcin08g03550 317 SM cluster DTC3 SANT/Myb domain + Homeodomain-like + Myb-like domain + Myb domain Bcin08g03560 573 SM cluster DTC3 (KE) Bcdtc3, Diterpen cyclase Bcin08g03570 495 SM cluster DTC3//SignalP-noTM Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin08g03580 131 Transporter//SM cluster DTC3 Major facilitator superfamily domain Bcin08g03590 305 SM cluster DTC3 Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin08g03600 96 SM cluster DTC3//Effector(V2)|Effector(V1) Multicopper oxidase, type 1 + Cupredoxin Bcin08g03610 193 SM cluster DTC3//Effector(V1) "Bccox4, similar to yeast COX4, Subunit IV of cytochrome c oxidase; the terminal member of the mitochondrial inner membrane electron transport chain; precursor N-terminal 25 residues are cleaved during mitochondrial import; phosphorylated; spermidine enhances translation [Source:SGD;Acc:S000003155]" Bcin08g03620 1039 Transporter//SM cluster DTC3 ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin08g03630 487 TRAM/LAG1/CLN8 homology domain + TRAM1-like protein + Ceramide synthase component Lag1/Lac1 Bcin08g03640 744 "Bcrim21, similar to yeast RIM21, pH sensor molecule, component of the RIM101 pathway; has a role in cell wall construction and alkaline pH response; is glycosylated and phosphorylated; interacts with Dfg16p and Rim9p to form a pH-sensing complex; localization to the plasma membrane is dependent on Dfg16p and Rim9p; has similarity to A. nidulans PalH [Source:SGD;Acc:S000005238]" Bcin08g03650 975 "Bcbud14, similar to yeast BUD14, Protein involved in bud-site selection; Bud14p-Glc7p complex is a cortical regulator of dynein; inhibitor of the actin assembly factor Bnr1p (formin); diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000000069]" Bcin08g03660 501 yes Signaling pathway Bcste50, Mitogen-activated protein kinase (MAPK) : Scaffold protein Bcin08g03670 489 Bcin08g03680 323 SignalP-noTM Bcin08g03690 165 Effector(V1) Bcin08g03700 823 "Bccdc48, similar to yeast CDC48, AAA ATPase; subunit of polyubiquitin-selective segregase complex involved in ERAD, cell wall integrity during heat stress, mitotic spindle disassembly; subunit of complex involved in mitochondria-associated degradation; role in mobilizing membrane bound transcription factors by regulated ubiquitin/proteasome-dependent processing, in macroautophagy, PMN, RAD, ribophagy, homotypic ER membrane fusion, disassembly of Met30p from SCF complex; functional ortholog of human p97/VCP [Source:SGD;Acc:S000002284]" Bcin08g03710 571 Bcnde2, External NADH dehydrogenase Bcin08g03720 232 Effector(V2) GNAT domain + Acyl-CoA N-acyltransferase Bcin08g03730 534 Bcin08g03740 276 Effector(V2) Beta-lactamase-like + Protein of unknown function DUF4336 Bcin08g03750 693 Bcin08g03760 403 Protease//SignalP-noTM//Early secretome Bcap10, Aspartic proteinase Bcin08g03770 162 "Bcvma11, similar to yeast VMA11, Vacuolar ATPase V0 domain subunit c'; involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen [Source:SGD;Acc:S000006155]" Bcin08g03780 1230 Dbl homology (DH) domain + DEP domain + Citron-like + Winged helix-turn-helix DNA-binding domain + Pleckstrin homology-like domain Bcin08g03790 228 "Bcphs1, similar to yeast PHS1, Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane; involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking [Source:SGD;Acc:S000003633]" Bcin08g03800 130 Effector(V1) GTPase effector domain, GED + Dynamin superfamily Bcin08g03810 392 Bcin08g03820 388 CAZy : PL1PCW pectin//SignalP-noTM Pectate lyase/Amb allergen + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin08g03830 258 yes SM cluster ABA//Effector(V2)|Effector(V1) Bcaba4, Dehydrogenase/reductase, in abscisic acid gene cluster Bcin08g03840 527 yes SM cluster ABA Bcaba2, Cytochrome P450 monooxygenase, in abscisic acid gene cluster Bcin08g03850 509 yes SM cluster ABA Bcaba1, Cytochrome P450 monooxygenase, in abscisic acid gene cluster Bcin08g03880 440 yes SM cluster ABA Bcaba3, In abscisic acid gene cluster Bcin08g03890 140 Effector(V2)|Effector(V1) Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Bcin08g03900 515 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin08g03910 373 yes Signaling pathway Bcpka2, PKA catalytic subunit Bcin08g03920 93 Effector(V2)|Effector(V1) Bcin08g03930 540 "Bcpfa5, similar to yeast PFA5, Palmitoyltransferase with autoacylation activity; likely functions in pathway(s) outside Ras; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain [Source:SGD;Acc:S000002867]" Bcin08g03940 87 SignalP-noTM//Effector(V1) Bcin08g03950 668 Cys2His2 transcription factor "Bcrad30, similar to yeast RAD30, DNA polymerase eta; involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; involved in formation of post-replicative damage-induced genome-wide cohesion; may also have a role in protection against mitochondrial mutagenesis; mutations in human pol eta are responsible for XPV [Source:SGD;Acc:S000002827]" Bcin08g03960 366 Bcin08g03970 566 SignalP-noTM Fungal lipase-like domain + Alpha/Beta hydrolase fold Bcin08g03980 703 AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain Bcin08g03990 377 CAZy : GT32 //SignalP-noTM Glycosyltransferase, DXD sugar-binding motif + Nucleotide-diphospho-sugar transferases Bcin08g04000 651 Cyclin-like + Cyclin PHO80-like Bcin08g04010 329 "Bcchs7, similar to yeast CHS7, Protein of unknown function; may be involved in chitin biosynthesis by regulation of Chs3p export from the ER; relocalizes from bud neck to ER upon DNA replication stress [Source:SGD;Acc:S000001184]" Bcin08g04020 553 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin08g04030 499 Aldehyde dehydrogenase domain + Aldehyde dehydrogenase, cysteine active site + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain + Aldehyde dehydrogenase, C-terminal + Aldehyde dehydrogenase, glutamic acid active site Bcin08g04040 756 Bcin08g04050 402 Bcin08g04060 690 FAD-binding 8 + Ferric reductase, NAD binding + Ferric reductase transmembrane component-like domain + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel Bcin08g04070 228 SignalP-noTM Bcin08g04080 499 Alpha/Beta hydrolase fold Bcin08g04090 121 Effector(V2)|Effector(V1) Bcin08g04100 526 SignalP-noTM TonB box, conserved site Bcin08g04110 686 Bcin08g04120 722 Protease//SignalP-noTM Alpha/beta hydrolase fold-1 + Dual specificity phosphatase, catalytic domain + Protein-tyrosine/Dual specificity phosphatase + Protein-tyrosine phosphatase, active site + Protein-tyrosine phosphatase-like + Alpha/Beta hydrolase fold Bcin08g04130 1072 Brefeldin A sensitivity protein-related, domain of unknown function DUF2421 + Domain of unknown function DUF2422 Bcin08g04140 804 Alpha/Beta hydrolase fold Bcin08g04150 1792 "Bcrrp5, similar to yeast RRP5, RNA binding protein involved in synthesis of both 18S and 5.8S rRNAs; component of both the ribosomal small subunit (SSU) processosome and the 90S preribosome; acts as part of a Mak21p-Noc2p-Rrp5p module that associates with nascent pre-rRNA during transcription and has a role in bigenesis of the large ribosomal subunit; has binding preference for single stranded tracts of U's; relocalizes from nucleolus to nucleus upon DNA replication stress [Source:SGD;Acc:S000004842]" Bcin08g04160 247 Effector(V2)|Effector(V1) Bcin08g04170 575 "Bctif3, similar to yeast TIF3, Translation initiation factor eIF-4B; contains an RNA recognition motif and binds to single-stranded RNA; has RNA annealing activity; interacts with Rps20p at the head of the 40S ribosomal subunit and alters the structure of the mRNA entry channel [Source:SGD;Acc:S000006367]" Bcin08g04180 542 "Bcdot1, similar to yeast DOT1, Nucleosomal histone H3-Lys79 methylase; methylation is required for telomeric silencing, meiotic checkpoint control, and DNA damage response [Source:SGD;Acc:S000002848]" Bcin08g04190 210 Autophagy-related protein 16 Bcin08g04200 205 Effector(V2)|Effector(V1) Small GTPase superfamily + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin08g04210 463 EamA domain + Protein of unknown function DUF3955 Bcin08g04220 305 Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin08g04230 486 Bcin08g04240 465 Haem oxygenase + Haem oxygenase-like + Haem oxygenase-like, multi-helical Bcin08g04250 331 JmjC domain Bcin08g04260 719 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site Bcin08g04270 824 "Bcspb1, similar to yeast SPB1, AdoMet-dependent methyltransferase; involved in rRNA processing and 60S ribosomal subunit maturation; methylates G2922 in the tRNA docking site of the large subunit rRNA and in the absence of snR52, U2921; suppressor of PAB1 mutants [Source:SGD;Acc:S000000559]" Bcin08g04280 381 CAZy : GH16FCW //SignalP-noTM Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin08g04290 812 Cys2His2 transcription factor + Fungal_trans Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin08g04300 1145 Ras-like guanine nucleotide exchange factor, N-terminal + SH3 domain + Ras guanine-nucleotide exchange factors catalytic domain + Ras guanine-nucleotide exchange factor, conserved site + Ras guanine nucleotide exchange factor domain Bcin08g04310 75 Effector(V1) Bcin08g04320 307 SignalP-noTM Ferritin-like superfamily + Ferritin-related Bcin08g04330 206 Bcin08g04340 253 Pre-mRNA-splicing factor 38 Bcin08g04350 76 Effector(V2)|Effector(V1) Bcin08g04360 922 "Bcvps34, similar to yeast VPS34, Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p; a fraction is localized, with Vps15p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery [Source:SGD;Acc:S000004230]" Bcin08g04370 477 "Bcnse4, similar to yeast NSE4, Component of the SMC5-SMC6 complex; this complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair [Source:SGD;Acc:S000002263]" Bcin08g04380 304 Domain of unknown function DUF1691 Bcin08g04390 170 Cys2His2 transcription factor//Effector(V1) Zinc finger, U1-type + Zinc finger, C2H2 + Zinc finger, double-stranded RNA binding Bcin08g04400 289 Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin08g04410 502 Protein of unknown function DUF3468 Bcin08g04420 424 "Bcisn1, similar to yeast ISN1, Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase; catalyzes the breakdown of IMP to inosine; responsible for production of nicotinamide riboside and nicotinic acid riboside; expression positively regulated by nicotinic acid and glucose availability; does not show similarity to known 5'-nucleotidases from other organisms [Source:SGD;Acc:S000005681]" Bcin08g04430 248 O-methyltransferase, family 3 + S-adenosyl-L-methionine-dependent methyltransferase Bcin08g04440 624 SignalP-noTM Calcineurin-like phosphoesterase domain, apaH type + 5'-Nucleotidase/apyrase + 5'-Nucleotidase, C-terminal + Predicted phosphoesterase, C1039.02 type + Metallo-dependent phosphatase-like Bcin08g04450 620 Amidase + Glutamyl-tRNA(Gln) amidotransferase A subunit + Amidase signature domain Bcin08g04460 288 Methyltransferase type 12 + S-adenosyl-L-methionine-dependent methyltransferase Bcin08g04470 282 Bcin08g04480 412 "Bcetr1, similar to yeast ETR1, 2-enoyl thioester reductase; member of the medium chain dehydrogenase/reductase family; localized to in mitochondria, where it has a probable role in fatty acid synthesis [Source:SGD;Acc:S000000230]" Bcin08g04490 535 "Bcncb2, similar to yeast NCB2, Subunit of a heterodimeric NC2 transcription regulator complex; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2beta; complex also includes Bur6p [Source:SGD;Acc:S000002805]" Bcin08g04500 362 Ribosomal protein S35, mitochondrial Bcin08g04510 282 Protein-tyrosine/Dual specificity phosphatase + Protein-tyrosine phosphatase, active site + Tyrosine/serine-protein phosphatase IphP-type + Protein-tyrosine phosphatase-like Bcin08g04520 234 Protein of unknown function DUF2052, coiled-coil Bcin08g04530 363 yes Bcatg3, Ubiquitin-like protein-activating enzyme, in autophagy process Bcin08g04540 372 "Bcpdb1, similar to yeast PDB1, E1 beta subunit of the pyruvate dehydrogenase (PDH) complex; PDH is an evolutionarily conserved multi-protein complex found in mitochondria [Source:SGD;Acc:S000000425]" Bcin08g04550 1481 Bcin08g04560 294 Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like Bcin08g04570 499 Zinc finger, DHHC-type transcription factor Zinc finger, DHHC-type, palmitoyltransferase Bcin08g04580 502 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger, C2H2-like Bcin08g04590 706 SignalP-noTM//Early secretome Six-hairpin glycosidase-like + Six-hairpin glycosidase Bcin08g04600 230 Effector(V2)|Effector(V1) DSBA-like thioredoxin domain + UV-endonuclease UvdE + Thioredoxin-like fold Bcin08g04610 260 Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin08g04620 782 Bcin08g04630 324 Bcin08g04640 605 Protein of unknown function DUF3468 Bcin08g04650 552 SignalP-noTM Transmembrane receptor, eukaryota Bcin08g04660 380 "Bcncs2, similar to yeast NCS2, Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs; required for the thiolation of uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae [Source:SGD;Acc:S000005063]" Bcin08g04670 310 Transporter Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin08g04680 391 "Bcswd2, similar to yeast SWD2, Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex; required for Set1C stability and optimal activity; COMPASS methylates histone H3 on lys 4 and is involved in telomeric silencing; subunit of CPF (cleavage and polyadenylation factor), a complex involved in RNAP II transcription termination [Source:SGD;Acc:S000001501]" Bcin08g04690 139 Bcin08g04700 477 Protease//SignalP-noTM Aspartic peptidase + Aspartic peptidase domain + Peptidase family A1 domain Bcin08g04710 1011 Zn2/Cys6 transcription factor "Bcaro80, similar to yeast ARO80, Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids [Source:SGD;Acc:S000002829]" Bcin08g04720 122 Bcin08g04730 343 "Bcfbp1, similar to yeast FBP1, Fructose-1,6-bisphosphatase; key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; glucose starvation results in redistribution to the periplasm; interacts with Vid30p [Source:SGD;Acc:S000004369]" Bcin08g04740 322 Bcin08g04750 341 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin08g04760 296 "Bccoq3, similar to yeast COQ3, O-methyltransferase; catalyzes two different O-methylation steps in ubiquinone (Coenzyme Q) biosynthesis; component of a mitochondrial ubiquinone-synthesizing complex; phosphoprotein [Source:SGD;Acc:S000005456]" Bcin08g04770 237 Effector(V2)|Effector(V1) "Bcrib3, similar to yeast RIB3, 3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase); required for riboflavin biosynthesis from ribulose-5-phosphate, also has an unrelated function in mitochondrial respiration [Source:SGD;Acc:S000002895]" Bcin08g04780 457 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin08g04790 132 Effector(V1) Bcin08g04800 67 Effector(V1) Bcin08g04810 669 Protease//SignalP-noTM Bccp6, Secreted protease Bcin08g04820 1409 "Bculs1, similar to yeast ULS1, Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL); required for maintenance of NHEJ inhibition at telomeres; functions at telomeres to translocate and ubiquitinylate poly-sumoylated Rap1p for proteosomal degradation; plays role in antagonizing silencing during mating-type switching; only known STUbL with a translocase activity; contains RING finger domain; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005717]" Bcin08g04830 634 Bcin08g04840 323 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal + Protein of unknown function DUF1295 Bcin08g04850 679 "Bclcb2, similar to yeast LCB2, Component of serine palmitoyltransferase; responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine [Source:SGD;Acc:S000002469]" Bcin08g04860 692 AMP-dependent synthetase/ligase + Acetoacetyl-CoA synthase + AMP-binding, conserved site + Acetyl-coenzyme A synthetase, N-terminal domain Bcin08g04870 815 "Bcdpb11, similar to yeast DPB11, DNA replication initiation protein; loads DNA pol epsilon onto pre-replication complexes at origins; checkpoint sensor recruited to stalled replication forks by the checkpoint clamp complex where it activates Mec1p; along with Rfa1p, binds to ultrafine anaphase bridges in mitotic cells and prevents accumulation of chromatin bridges by stimulating the Mec1p kinase and suppressing homologous recombination; ortholog of human TopBP1; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000003626]" Bcin08g04880 223 Effector(V2)|Effector(V1) Isochorismatase-like Bcin08g04890 884 Arrestin C-terminal-like domain Bcin08g04900 620 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin08g04910 304 NmrA-like domain + NAD(P)-binding domain Bcin08g04920 817 Zn2/Cys6 transcription factor + Cys2His2 + Fungal_trans Zn(2)-C6 fungal-type DNA-binding domain + Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin08g04930 575 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin08g04940 292 Bcin08g04950 752 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase + Alkaline phosphatase-like, alpha/beta/alpha + Alkaline-phosphatase-like, core domain Bcin08g04960 288 Bcin08g04970 580 Transporter Amino acid/polyamine transporter I Bcin08g04980 174 Effector(V2)|Effector(V1) CMP/dCMP deaminase, zinc-binding + Cytidine deaminase-like Bcin08g04990 956 Protease WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin08g05000 370 Ethanolamine utilisation EutQ + RmlC-like cupin domain + RmlC-like jelly roll fold Bcin08g05010 230 SignalP-noTM Bcin08g05020 204 SignalP-noTM Bcin08g05030 874 Jacalin-like lectin domain Bcin08g05040 566 Carboxyl transferase + Acetyl-coenzyme A carboxyltransferase, N-terminal + Acetyl-coenzyme A carboxyltransferase, C-terminal + ClpP/crotonase-like domain Bcin08g05050 430 Acyl-CoA dehydrogenase, conserved site + Acyl-CoA oxidase/dehydrogenase, central domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase/oxidase, N-terminal Bcin08g05060 362 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin08g05070 605 "Bccti6, similar to yeast CTI6, Component of the Rpd3L histone deacetylase complex; relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain [Source:SGD;Acc:S000006102]" Bcin08g05080 621 Bcin08g05090 357 Oxoglutarate/iron-dependent dioxygenase + Prolyl 4-hydroxylase, alpha subunit Bcin08g05100 704 Biotin/lipoyl attachment + Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain + Carbamoyl-phosphate synthase, large subunit, N-terminal + Biotin carboxylase, C-terminal + Single hybrid motif + Rudiment single hybrid motif + ATP-grasp fold + Biotin carboxylation domain + ATP-grasp fold, subdomain 1 + ATP-grasp fold, subdomain 2 + Pre-ATP-grasp domain Bcin08g05110 237 Effector(V2) YjeF N-terminal domain + YjeF N-terminal domain-containing protein, eukaryotes Bcin08g05120 114 Effector(V1) "Bcmrps16, similar to yeast MRPS16, Mitochondrial ribosomal protein of the small subunit [Source:SGD;Acc:S000005934]" Bcin08g05130 502 Transporter Amino acid transporter, transmembrane domain Bcin08g05140 209 Effector(V1) Dynactin subunit p22 Bcin08g05150 312 yes Signaling pathway BcSho1, Biosensor of HOG pathway Bcin08g05160 1048 Importin-beta, N-terminal domain + Armadillo-like helical + Exportin/Importin, Cse1-like + Armadillo-type fold Bcin08g05170 323 SignalP-noTM Bcin08g05180 343 "Bccwc24, similar to yeast CWC24, General splicing factor; required for stable U2 snRNP binding to primary transcripts; essential for the first step of splicing; component of the pre-catalytic spliceosome complex containing Cef1p; similar to S. pombe Cwf24p [Source:SGD;Acc:S000004315]" Bcin08g05190 1715 Pleckstrin homology domain + Pleckstrin homology-like domain + Pleckstrin homology domain, Mcp5-type Bcin08g05200 522 Cytochrome P450 + Cytochrome P450, E-class, group II + Cytochrome P450, E-class, CYP52 + Cytochrome P450, conserved site Bcin08g05210 595 Bcin08g05220 255 Effector(V2)|Effector(V1) Triosephosphate isomerase + Aldolase-type TIM barrel + Triosephosphate isomerase, active site + Triosephosphate isomerase, bacterial/eukaryotic Bcin08g05230 137 Effector(V2)|Effector(V1) "Bcmrpl51, similar to yeast MRPL51, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000006304]" Bcin08g05240 436 "Bcsnp1, similar to yeast SNP1, Component of U1 snRNP required for mRNA splicing via spliceosome; substrate of the arginine methyltransferase Hmt1p; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001323]" Bcin08g05250 237 Effector(V2)|Effector(V1) "Bcmrt4, similar to yeast MRT4, Protein involved in mRNA turnover and ribosome assembly; required at post-transcriptional step for efficient retrotransposition; localizes to the nucleolus [Source:SGD;Acc:S000001492]" Bcin08g05260 400 "Bcmdm10, similar to yeast MDM10, Subunit of both the ERMES and the SAM complex; component of ERMES complex which acts as a molecular tether between the mitochondria and the ER, necessary for efficient phospholipid exchange between organelles and for mitophagy; SAM/TOB complex component that functions in the assembly of outer membrane beta-barrel proteins; involved in mitochondrial inheritance and morphology; ERMES complex is often co-localized with peroxisomes and concentrated areas of pyruvate dehydrogenase [Source:SGD;Acc:S000000008]" Bcin08g05270 395 "Bczrt2, similar to yeast ZRT2, Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor [Source:SGD;Acc:S000004120]" Bcin08g05280 330 SignalP-noTM Beta-lactamase-like Bcin08g05290 504 CAZy : GT15 Glycosyl transferase, family 15 + Nucleotide-diphospho-sugar transferases Bcin08g05300 187 Domain of unknown function DUF4604 Bcin08g05310 231 yes Bctaf14, TATA box-binding protein (TBP)-associated factor 14 Bcin08g05320 261 "Bcyrb1, similar to yeast YRB1, Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1 [Source:SGD;Acc:S000002409]" Bcin08g05330 433 Bcin08g05340 509 F-box domain Bcin08g05350 261 Effector(V1) DeoC/FbaB/ lacD aldolase + Deoxyribose-phosphate aldolase + Aldolase-type TIM barrel + Deoxyribose-phosphate aldolase type I Bcin08g05360 487 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin08g05370 353 SignalP-noTM Bcin08g05380 283 "Bctad2, similar to yeast TAD2, Subunit of tRNA-specific adenosine-34 deaminase; forms a heterodimer with Tad3p that converts adenosine to inosine at the wobble position of several tRNAs [Source:SGD;Acc:S000003572]" Bcin08g05390 189 Effector(V2)|Effector(V1) NADH-ubiquinone oxidoreductase, 21kDa subunit, N-terminal + NADH-ubiquinone oxidoreductase, 21kDa subunit, C-terminal, fungi Bcin08g05400 338 Replication fork protection component Swi3 Bcin08g05410 1278 "Bcski2, similar to yeast SKI2, Ski complex component and putative RNA helicase; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, SKIV2L, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome [Source:SGD;Acc:S000004390]" Bcin08g05420 346 Bcin08g05430 709 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin08g05440 614 Ankyrin repeat + Ankyrin repeat-containing domain Bcin08g05450 294 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin08g05460 448 Bcin08g05470 574 Sulfatase + Choline-sulfatase + Alkaline phosphatase-like, alpha/beta/alpha + Alkaline-phosphatase-like, core domain + Sulfatase, conserved site + Choline sulfatase enzyme C-terminal domain Bcin08g05480 291 CAZy : GH16FCW //SignalP-noTM Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin08g05490 403 Bcin08g05500 547 Protease Peptidase S54, rhomboid + Peptidase S54, rhomboid domain Bcin08g05510 1106 "Bcpol3, similar to yeast POL3, Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER) [Source:SGD;Acc:S000002260]" Bcin08g05520 536 Bcin08g05530 222 Bcin08g05540 246 SignalP-noTM CND1, CalciNeurine-Dependant (CND) gene,Gas1-like Bcin08g05550 329 Urease accessory protein UreD Bcin08g05560 1176 "Bcirr1, similar to yeast IRR1, Subunit of the cohesin complex; which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms; relocalizes to the cytosol in response to hypoxia; essential for viability [Source:SGD;Acc:S000001288]" Bcin08g05570 749 Zn2/Cys6 + fungal trans transcription factor Bcltf9, BcnirA, Zn2/Cys6 transcription factor Bcin08g05580 419 NTF2-like domain Bcin08g05590 485 "Bcsqt1, similar to yeast SQT1, Protein involved in 60S ribosomal subunit assembly or modification; contains multiple WD repeats; interacts with Qsr1p in a two-hybrid assay; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001451]" Bcin08g05600 583 AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain Bcin08g05610 57 Effector(V2)|Effector(V1) Bcin08g05620 829 Oxoglutarate/iron-dependent dioxygenase + Alpha-ketoglutarate-dependent dioxygenase AlkB-like Bcin08g05630 164 Effector(V2)|Effector(V1)//Early secretome Cyanate lyase, C-terminal + Cyanate hydratase + Lambda repressor-like, DNA-binding domain Bcin08g05640 349 SET domain Bcin08g05650 564 SET domain + Zinc finger, MYND-type Bcin08g05660 182 Effector(V1) Bcin08g05670 171 Bcin08g05680 151 Effector(V2)|Effector(V1) Bcin08g05690 481 Bcin08g05700 425 NUDIX hydrolase domain + NUDIX hydrolase domain-like Bcin08g05710 194 Effector(V1) Bcin08g05720 215 F-box domain + Leucine-rich repeat domain, L domain-like Bcin08g05730 359 Ankyrin repeat + Ankyrin repeat-containing domain Bcin08g05740 158 Effector(V2)|Effector(V1) Bcin08g05750 242 Bcin08g05760 735 Telomeric single stranded DNA binding POT1/Cdc13 + Nucleic acid-binding, OB-fold + Protection of telomeres protein 1 + Protection of telomeres protein 1, ssDNA-binding domain Bcin08g05770 551 "Bcsrp1, similar to yeast SRP1, Karyopherin alpha homolog; forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; involved in cotranslational protein degradation; binds ribosome-bound nascent polypeptides; Srp1p and Sts1p couple proteasomes to nascent polypeptides emerging from the ribosome for cotranslational degradation [Source:SGD;Acc:S000005133]" Bcin08g05780 515 Protease Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin08g05790 171 Bcin08g05800 1023 Aspartyl/Asparaginyl-tRNA synthetase, class IIb + Aminoacyl-tRNA synthetase, class II (D/K/N) + Aspartyl-tRNA synthetase, archaeal-type + Aminoacyl-tRNA synthetase, class II + Nucleic acid-binding, OB-fold + Lysylphosphatidylglycerol synthetase, domain of unknown function DUF2156 Bcin08g05810 351 GroES (chaperonin 10)-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin08g05820 133 Effector(V1) Bcin08g05830 735 "Bcmkt1, similar to yeast MKT1, Protein similar to nucleases that forms a complex with Pbp1p; complex may mediate posttranscriptional regulation of HO; involved in propagation of M2 dsRNA satellite of L-A virus; allelic variation affects mitochondrial genome stability, drug resistance, and more; forms cytoplasmic foci upon DNA replication stress; localization to P-bodies under ethanol stress differs between strains [Source:SGD;Acc:S000005029]" Bcin08g05840 353 Oxoglutarate/iron-dependent dioxygenase + Non-haem dioxygenase N-terminal domain + Isopenicillin N synthase-like Bcin08g05850 453 "Bcpus4, similar to yeast PUS4, Pseudouridine synthase; catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; also responsible for pseudouracil modification of some mRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype) [Source:SGD;Acc:S000005236]" Bcin08g05860 495 Bcin08g05870 792 CAZy : GH95PCW pectin//SignalP-noTM//Early secretome Six-hairpin glycosidase-like + Alpha-L-fucosidase + Glycosyl hydrolase family, N-terminal domain Bcin08g05880 635 "Bcmub1, similar to yeast MUB1, MYND domain-containing protein; required for ubiquitination and turnover of Rpn4p; interacts with Ubr2p (E3) and indirectly with Rad6p (E2); short-lived protein degraded in a Ubr2p/Rad6p dependent manner; similar to the A. nidulans samB gene [Source:SGD;Acc:S000004706]" Bcin08g05890 387 "Bcebp2, similar to yeast EBP2, Required for 25S rRNA maturation and 60S ribosomal subunit assembly; localizes to the nucleolus and in foci along nuclear periphery; constituent of 66S pre-ribosomal particles; cooperates with Rrs1p and Mps3p to mediate telomere clustering by binding Sir4p, but is not involved in telomere tethering [Source:SGD;Acc:S000001655]" Bcin08g05900 356 Bcin08g05910 471 "Bczrg17, similar to yeast ZRG17, Endoplasmic reticulum zinc transporter; part of a heterodimeric transporter with Msc2p that transfers zinc from the cytosol to the ER lumen; member of the cation diffusion facilitator family of efflux pumps; zinc-regulated directly through Zap1p; transcription induced under conditions of zinc deficiency [Source:SGD;Acc:S000005322]" Bcin08g05920 945 Dynamin central domain + Dynamin, GTPase domain + Dynamin, GTPase region, conserved site + GTPase effector domain, GED + Dynamin superfamily + P-loop containing nucleoside triphosphate hydrolase + Dynamin-type guanine nucleotide-binding (G) domain Bcin08g05930 474 Protease "Bcdug3, similar to yeast DUG3, Component of glutamine amidotransferase (GATase II); forms a complex with Dug2p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p) [Source:SGD;Acc:S000005135]" Bcin08g05940 572 Bcin08g05950 194 Effector(V1) Bcin08g05960 281 "Bcers1, similar to yeast ERS1, Protein with similarity to human cystinosin; cystinosin is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains [Source:SGD;Acc:S000000671]" Bcin08g05970 560 Transporter Amino acid/polyamine transporter I + Amino acid permease, conserved site + Amino acid permease/ SLC12A domain Bcin08g05980 594 Bcin08g05990 250 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin08g06000 428 CAZy : GT32 Glycosyltransferase, DXD sugar-binding motif + Nucleotide-diphospho-sugar transferases Bcin08g06010 710 Bcin08g06020 717 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin08g06030 637 Cyclin, C-terminal domain + Cyclin, N-terminal + Cyclin-like Bcin08g06040 706 Transporter "Bcagc1, similar to yeast AGC1, Mitochondrial amino acid transporter; acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis [Source:SGD;Acc:S000006225]" Bcin08g06050 501 Clr5 domain Bcin08g06060 252 Bcin08g06070 275 Bcin08g06080 616 Bcin08g06090 648 DNA-directed RNA polymerase III subunit RPC4 Bcin08g06100 428 SignalP-noTM Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin08g06110 441 CAZy : GH76FCW //SignalP-noTM//Early secretome Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase + Mannan endo-1,6-alpha-mannosidase Bcin08g06120 201 Effector(V2) Bcin08g06130 157 Effector(V1) Bcin08g06140 820 SignalP-noTM Bcin08g06150 618 YAP-binding/ALF4/Glomulin Bcin08g06160 349 CAZy : GH53PCW hemicellulose or pectin//SignalP-noTM Glycosyl hydrolase family 53 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin08g06170 442 Bcin08g06180 608 Heat shock protein 70 family Bcin08g06190 358 Bcin08g06200 1145 "Bcmip1, similar to yeast MIP1, Mitochondrial DNA polymerase gamma subunit; conserved C-terminal segment is required for the maintenance of mitochondrial genome; its human ortholog, POLG, can rescue mip1 phenotypes, and mutations in POLG are associated with Alpers-Huttenlocher syndrome (AHS) and other mitochondrial diseases; Mip1p is the single subunit of mitochondrial DNA polymerase in yeast, in contrast to metazoans in which there is a complex of a catalytic subunit and an accessory subunit [Source:SGD;Acc:S000005857]" Bcin08g06210 404 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site Bcin08g06220 884 Bcin08g06230 606 Low temperature requirement A Bcin08g06240 420 Monooxygenase, FAD-binding + FAD binding domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin08g06250 2465 "Bcmec1, similar to yeast MEC1, Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres [Source:SGD;Acc:S000000340]" Bcin08g06260 115 Effector(V1) "Bccox16, similar to yeast COX16, Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase [Source:SGD;Acc:S000003540]" Bcin08g06270 373 Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold + Lipase, GDXG, putative serine active site Bcin08g06280 639 SignalP-noTM Myxococcus cysteine-rich repeat Bcin08g06290 603 F-box domain Bcin08g06300 791 Phosphofructokinase domain + ATP-dependent 6-phosphofructokinase, eukaryotic-type + Phosphofructokinase, conserved site + ATP-dependent 6-phosphofructokinase Bcin08g06310 697 "Bcsrb4, similar to yeast SRB4, Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for basal RNA polymerase II transcription; homozygosity of the human MED17 L371P mutation is associated with infantile cerebral and cerebellar atrophy with poor myelination [Source:SGD;Acc:S000000824]" Bcin08g06320 436 Zinc finger, PARP-type Bcin08g06330 321 Bcin08g06340 264 Bcin08g06350 222 SignalP-noTM Bcin08g06360 372 Bcin08g06370 240 Transporter//Effector(V1) Protein of unknown function DUF2196 Bcin08g06380 471 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin08g06390 269 Bcin08g06400 200 Effector(V1) Bcin08g06410 282 "Bcgpi12, similar to yeast GPI12, ER membrane protein involved in the second step of GPI anchor assembly; the second step is the de-N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate; functional homolog of human PIG-Lp; GPI stands for glycosylphosphatidylinositol [Source:SGD;Acc:S000004894]" Bcin08g06420 331 S-adenosyl-L-methionine-dependent methyltransferase Bcin08g06430 761 ATPase expression protein 2, mitochondrial Bcin08g06440 98 "Bclsm3, similar to yeast LSM3, Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; protein increases in abundance and relocalizes from nucleus to cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000006434]" Bcin08g06450 638 Elongation factor, GTP-binding domain + Translation elongation factor EFTu/EF1A, domain 2 + Translation protein, beta-barrel domain + Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal + P-loop containing nucleoside triphosphate hydrolase Bcin08g06460 319 Bcin08g06470 1292 P-loop containing nucleoside triphosphate hydrolase Bcin08g06480 696 "Bcspt8, similar to yeast SPT8, Subunit of the SAGA transcriptional regulatory complex; not present in SAGA-like complex SLIK/SALSA; required for SAGA-mediated inhibition at some promoters [Source:SGD;Acc:S000004045]" Bcin08g06490 440 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin08g06500 243 Bcin08g06510 184 Cytochrome P450 Bcin08g06520 307 Bcin08g06530 169 Effector(V1) Bcin08g06540 153 Effector(V1) Histone H3/CENP-A + Histone core + Histone-fold Bcin08g06550 441 "Bcinp54, similar to yeast INP54, Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; role in secretion; localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins [Source:SGD;Acc:S000005426]" Bcin08g06560 614 Major facilitator superfamily + Major facilitator superfamily domain Bcin08g06570 350 Protein of unknown function DUF1749 + Alpha/Beta hydrolase fold Bcin08g06580 391 Bcin08g06590 294 Alpha/gamma-adaptin-binding protein p34 Bcin08g06600 117 Effector(V2)|Effector(V1) Ribonucleoprotein LSM domain + Like-Sm (LSM) domain + U6 snRNA-associated Sm-like protein LSm4/Small nuclear ribonucleoprotein Sm D1/D3 Bcin08g06610 217 Effector(V2)|Effector(V1) "Bcgep4, similar to yeast GEP4, Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase); dephosphorylates phosphatidylglycerolphosphate to generate phosphatidylglycerol, an essential step during cardiolipin biosynthesis; null mutant is sensitive to tunicamycin, DTT [Source:SGD;Acc:S000001142]" Bcin08g06620 582 yes Homeobox transcription factor//Signaling pathway Bchox8, Homeobox transcription factor Bcin08g06630 1702 Transporter "Bcdnf3, similar to yeast DNF3, Trans-golgi network aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; localizes to the trans-Golgi network; likely involved in protein transport; type 4 P-type ATPase [Source:SGD;Acc:S000004772]" Bcin08g06640 1789 "Bchfm1, similar to yeast HFM1, Meiosis specific DNA helicase; involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity [Source:SGD;Acc:S000003220]" Bcin08g06650 470 Transporter Nucleotide-sugar transporter Bcin08g06660 745 Bcin08g06670 691 "Bchop1, similar to yeast HOP1, Meiosis-specific protein required for chromosome synapsis; displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for chiasma formation; in vitro, displays the ability to promote intra- and intermolecular synapsis between double-stranded DNA molecules and to fold DNA into rigid protein-DNA filaments [Source:SGD;Acc:S000001334]" Bcin08g06680 1042 "Bccdc4, similar to yeast CDC4, F-box protein required for both the G1/S and G2/M phase transitions; modular substrate specificity factor which associates with core SCF (Cdc53p, Skp1p and Hrt1p/Rbx1p) to form the SCFCdc4 complex; SCFCdc4 acts as a ubiquitin-protein ligase directing ubiquitination of cyclin-dependent kinase (CDK) phosphorylated substrates, such as: Sic1p, Far1p, Cdc6p, Clb6p, and Cln3p [Source:SGD;Acc:S000001885]" Bcin08g06690 269 Effector(V2) Bcin08g06700 323 "Bchch1, similar to yeast HCH1, Heat shock protein regulator; binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; role in regulating Hsp90 inhibitor drug sensitivity; GFP-fusion protein localizes to the cytoplasm and nucleus; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005225]" Bcin08g06710 222 Effector(V2)|Effector(V1) Bcin08g06720 428 Bcin08g06730 517 Bzip transcription factor "Bchac1, similar to yeast HAC1, Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog); regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway facilitates efficient Hac1p synthesis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001863]" Bcin08g06740 573 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + U box domain + Zinc finger, RING/FYVE/PHD-type + Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site + Cyclophilin-type peptidyl-prolyl cis-trans isomerase + Cyclophilin-like domain Bcin08g06750 297 "Bctfa2, similar to yeast TFA2, TFIIE small subunit; involved in RNA polymerase II transcription initiation [Source:SGD;Acc:S000001770]" Bcin08g06760 2057 Tetratricopeptide, MLP1/MLP2-like Bcin08g06770 188 Effector(V2)|Effector(V1) Bacterial transferase hexapeptide repeat + Trimeric LpxA-like + Dynactin subunit 6 Bcin08g06780 509 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site + NADH ubiquinone oxidoreductase, F subunit + NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain + Soluble ligand binding domain + NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain Bcin08g06790 290 Peroxisomal biogenesis factor 11 Bcin08g06800 176 Bcin08g06810 475 Bcin08g06820 527 Zinc finger, CCHC-type Bcin08g06830 827 CAZy : GH3PCW/FCW //SignalP-noTM Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Fibronectin type III-like domain Bcin08g06840 440 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain Bcin08g06850 323 Bcin08g06860 2613 Cys2His2 transcription factor Zinc finger, C2H2 Bcin08g06870 119 Effector(V2)|Effector(V1) Bcin08g06880 172 Bcin08g06890 587 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB Bcin08g06900 128 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1)//Early secretome Apple-like Bcin08g06910 130 Effector(V2)|Effector(V1) Bcin08g06920 286 "Bchnt3, similar to yeast HNT3, DNA 5' AMP hydrolase involved in DNA repair; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins; homolog of Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia; relative distribution to nuclear foci decreases upon DNA replication stress [Source:SGD;Acc:S000005784]" Bcin08g06930 1385 Helicase, C-terminal + DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site + RWD domain + Helicase-associated domain + DEAD/DEAH box helicase domain + Domain of unknown function DUF1605 + Helicase superfamily 1/2, ATP-binding domain + Ubiquitin-conjugating enzyme/RWD-like + P-loop containing nucleoside triphosphate hydrolase Bcin08g06940 186 Effector(V2)|Effector(V1) Domain of unknown function DUF302 Bcin08g06950 161 Effector(V2)|Effector(V1) "Bctim17, similar to yeast TIM17, Essential component of the TIM23 complex; with Tim23p, contributes to the architecture and function of the import channel; may link the import motor to the core Translocase of the Inner Mitochondrial membrane (TIM23 complex) [Source:SGD;Acc:S000003679]" Bcin08g06960 369 Bcin08g06970 380 Protein of unknown function DUF2985 Bcin08g06980 327 Bcin08g06990 1845 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin08g07000 563 WW domain + FF domain Bcin08g07010 256 Protease//Effector(V1) "Bcpre9, similar to yeast PRE9, Alpha 3 subunit of the 20S proteasome; the only nonessential 20S subunit; may be replaced by the alpha 4 subunit (Pre6p) under stress conditions to create a more active proteasomal isoform [Source:SGD;Acc:S000003367]" Bcin08g07020 676 Bcin08g07030 266 Bcin08g07040 1066 Cytochrome P450 + Oxidoreductase FAD/NAD(P)-binding + Cytochrome P450, E-class, group I + FAD-binding, type 1 + Flavodoxin/nitric oxide synthase + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel + Cytochrome P450, conserved site + NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 + Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase + Flavoprotein-like Bcin08g07050 429 CAZy : GH18FCW //SignalP-noTM BcchiA, Fungal family 18 chitinases, group A, clades A-V, subclades CHI18-5/CHI18-7 (Choquer et al., mycological research 111 (2007) 615-625) Bcin08g07060 591 SignalP-noTM "Bcgpi16, similar to yeast GPI16, Subunit of the glycosylphosphatidylinositol transamidase complex; transmembrane protein; adds GPIs to newly synthesized proteins; human PIG-Tp homolog [Source:SGD;Acc:S000001231]" Bcin08g07070 286 Effector(V1) "Bcluc7, similar to yeast LUC7, Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002245]" Bcin08g07080 195 Effector(V2)|Effector(V1) Bcin08g07090 144 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin08g07100 535 Bcin08g07110 948 P-loop containing nucleoside triphosphate hydrolase Bcin08g07120 353 SignalP-noTM Intradiol ring-cleavage dioxygenase, core Bcin08g07140 275 Beta-lactamase-like Bcin09g00020 464 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin09g00030 239 Effector(V2)|Effector(V1) NAD(P)-binding domain Bcin09g00040 343 Glutamine synthetase, catalytic domain + Glutamine synthetase/guanido kinase, catalytic domain Bcin09g00050 334 SignalP-TM Methyltransferase domain Bcin09g00060 218 SignalP-noTM Bcin09g00070 598 Protein of unknown function DUF1365 Bcin09g00080 208 Effector(V1) "Bcmbf1, similar to yeast MBF1, Transcriptional coactivator; bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000007253]" Bcin09g00090 532 DNA replication factor Cdt1, C-terminal Bcin09g00100 261 Bcin09g00110 310 Bcin09g00120 340 "Bcget3, similar to yeast GET3, Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; functions as a chaperone under ATP-depleted oxidative stress conditions; subunit of the GET complex, which is involved in ATP dependent Golgi to ER trafficking and insertion of tail-anchored (TA) proteins into the ER membrane under non-stress conditions; has low-level ATPase activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002258]" Bcin09g00130 166 Effector(V2)|Effector(V1) Hydroxyisourate hydrolase + Transthyretin/hydroxyisourate hydrolase, superfamily Bcin09g00140 213 Bcin09g00150 592 Transporter Bchex1, Similar to MFS sugar transporter Bcin09g00160 670 3-dehydroquinate dehydratase type I + Aldolase-type TIM barrel Bcin09g00170 817 yes Zn2/Cys6 + fungal trans transcription factor BcgaaR, Zn2/Cys6 transcription factor, B. cinerea GalA Regulator Bcin09g00180 909 Major facilitator superfamily + Major facilitator superfamily domain Bcin09g00190 462 CAZy : GH76FCW //SignalP-noTM Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase + Mannan endo-1,6-alpha-mannosidase Bcin09g00200 453 CAZy : GH17FCW //SignalP-noTM//Early secretome Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin09g00210 548 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin09g00220 139 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin09g00230 722 "Bcmag2, similar to yeast MAG2, Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1 [Source:SGD;Acc:S000004419]" Bcin09g00240 881 Protease "Bcubp3, similar to yeast UBP3, Ubiquitin-specific protease involved in transport and osmotic response; interacts with Bre5p to co-regulate anterograde and retrograde transport between the ER and Golgi; involved in transcription elongation in response to osmostress through phosphorylation at Ser695 by Hog1p; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin; also has mRNA binding activity; protein abundance increases in response to DNA replication stress; role in ribophagy [Source:SGD;Acc:S000000953]" Bcin09g00250 565 Ergosterol biosynthesis ERG4/ERG24 + Sterol reductase, conserved site Bcin09g00260 1031 Protease "Bcspt16, similar to yeast SPT16, Subunit of the heterodimeric FACT complex (Spt16p-Pob3p); FACT associates with chromatin via interaction with Nhp6Ap and Nhp6Bp, and reorganizes nucleosomes to facilitate access to DNA by RNA and DNA polymerases; SPT16 specifically required for diauxic shift-induced H2B deposition onto rDNA genes; some mutations cause reduced nucleosome occupancy over highly transcribed regions of the yeast genome [Source:SGD;Acc:S000003175]" Bcin09g00270 1846 Forkhead-associated (FHA) domain + Kinesin motor domain + Pleckstrin homology domain + SMAD/FHA domain + Pleckstrin homology-like domain + Kinesin motor domain, conserved site + Kinesin protein 1B + Kinesin-like + P-loop containing nucleoside triphosphate hydrolase + Kinesin-associated Bcin09g00280 206 Effector(V2)|Effector(V1) Zinc finger, CCHC-type Bcin09g00290 718 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin09g00300 311 SignalP-noTM Deoxyribonuclease NucA/NucB Bcin09g00310 513 Bcin09g00320 429 Bcin09g00330 321 Bcin09g00340 931 Com1/Ctip family + DNA endonuclease RBBP8-like Bcin09g00350 430 CDC50/LEM3 family Bcin09g00360 258 Bcin09g00370 631 Patatin/Phospholipase A2-related + Acyl transferase/acyl hydrolase/lysophospholipase Bcin09g00380 329 SignalP-noTM Alpha/Beta hydrolase fold Bcin09g00390 326 Bcin09g00400 157 Bcin09g00410 189 SignalP-noTM Bcin09g00420 359 Rossmann-like alpha/beta/alpha sandwich fold Bcin09g00430 208 Bcin09g00440 558 Transporter Amino acid/polyamine transporter I Bcin09g00450 587 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin09g00460 368 SignalP-noTM Bcin09g00470 319 SignalP-noTM Beta-lactamase-like Bcin09g00480 478 Early secretome Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin09g00490 476 "Bcmep2, similar to yeast MEP2, Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation [Source:SGD;Acc:S000005086]" Bcin09g00500 91 Effector(V1) Bcin09g00510 416 SignalP-noTM "Bcscj1, similar to yeast SCJ1, One of several homologs of bacterial chaperone DnaJ; located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins [Source:SGD;Acc:S000004827]" Bcin09g00520 180 Marvel domain Bcin09g00530 312 Major intrinsic protein + Aquaporin-like + Aquaporin transporter Bcin09g00540 292 Effector(V2) NADH-quinone oxidoreductase subunit E-like + Thioredoxin-like fold Bcin09g00550 259 S-adenosyl-L-methionine-dependent methyltransferase Bcin09g00560 494 Transcription factor TFIIIC, tau55-related Bcin09g00570 447 Bcin09g00580 332 Ketopantoate reductase ApbA/PanE + 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + Ketopantoate reductase, N-terminal domain + Ketopantoate reductase, C-terminal domain + NAD(P)-binding domain Bcin09g00590 498 Glutamine synthetase, catalytic domain + Glutamine synthetase, beta-Grasp + Glutamine synthetase/guanido kinase, catalytic domain Bcin09g00600 305 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin09g00610 185 Bcin09g00620 810 SignalP-noTM Bccda4, Chitin deacetylase Bcin09g00630 256 Bcin09g00640 135 Bcin09g00650 473 "Bccit3, similar to yeast CIT3, Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate [Source:SGD;Acc:S000006205]" Bcin09g00660 596 yes Bcmcl, Methyl isocitrate lyase Bcin09g00670 181 Bcin09g00680 248 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin09g00690 98 Effector(V2)|Effector(V1) Bcin09g00700 277 Bcin09g00710 261 Bcin09g00720 383 "Bcdit1, similar to yeast DIT1, Sporulation-specific enzyme required for spore wall maturation; involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall; transcripts accumulate at the time of prospore enclosure [Source:SGD;Acc:S000002811]" Bcin09g00730 579 Major facilitator superfamily + Major facilitator superfamily domain Bcin09g00740 485 Protein of unknown function DUF3468 Bcin09g00750 334 Zinc finger, RING-type + Zinc finger, RING-CH-type + Zinc finger, RING/FYVE/PHD-type Bcin09g00760 198 Cys2His2 transcription factor//Effector(V1) Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin09g00770 377 Early secretome Six-bladed beta-propeller, TolB-like + SMP-30/Gluconolactonase/LRE-like region Bcin09g00780 234 Effector(V1) Bcin09g00790 412 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin09g00800 292 RTA-like protein Bcin09g00810 269 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin09g00820 217 Bcgst6, Glutathione S-transferase Bcin09g00830 564 Tetratricopeptide-like helical domain + Tetratricopeptide repeat Bcin09g00840 541 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin09g00850 349 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin09g00860 136 Effector(V2)|Effector(V1) Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin09g00870 1120 "Bcnew1, similar to yeast NEW1, ATP binding cassette protein; cosediments with polysomes and is required for biogenesis of the small ribosomal subunit; Asn/Gln-rich rich region supports [NU+] prion formation and susceptibility to [PSI+] prion induction [Source:SGD;Acc:S000006147]" Bcin09g00880 289 Protein of unknown function DUF1275 Bcin09g00890 207 Bcin09g00900 163 Bcin09g00910 308 NmrA-like domain + NAD(P)-binding domain Bcin09g00920 521 yes Bzip transcription factor//Signaling pathway Bcatf1, Bzip transcription factor Bcin09g00930 334 Glutathione S-transferase, N-terminal + Glutathione S-transferase, C-terminal-like + Thioredoxin-like fold Bcin09g00940 79 Effector(V1) Bcin09g00950 91 Effector(V1) Bcin09g00960 539 Major facilitator superfamily + Major facilitator superfamily domain Bcin09g00970 393 SignalP-noTM Bcin09g00980 450 Isocitrate dehydrogenase NADP-dependent + Isocitrate/isopropylmalate dehydrogenase, conserved site + Isopropylmalate dehydrogenase-like domain Bcin09g00990 377 INO80 complex subunit 3 Bcin09g01000 495 "Bcnop13, similar to yeast NOP13, Nucleolar protein found in preribosomal complexes; contains an RNA recognition motif (RRM); relative distribution to the nucleolus increases upon DNA replication stress [Source:SGD;Acc:S000005119]" Bcin09g01010 598 Butirosin biosynthesis, BtrG-like Bcin09g01020 197 Effector(V1) Ribonuclease/ribotoxin Bcin09g01030 308 Protein of unknown function DUF3632 Bcin09g01040 399 L-asparaginase, type II + Asparaginase/glutaminase + Asparaginase/glutaminase, active site 1 + L-asparaginase, C-terminal domain + L-asparaginase, N-terminal + Asparaginase/glutaminase, active site 2 Bcin09g01050 270 Bcin09g01060 242 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Protein of unknown function DUF3129 Bcin09g01070 519 Multi antimicrobial extrusion protein Bcin09g01080 706 Btz domain Bcin09g01090 114 Bcin09g01100 75 Bcin09g01110 599 SignalP-noTM//Early secretome Cellulose-binding domain, fungal + Glycoside hydrolase, family 7 + Concanavalin A-like lectin/glucanase domain Bcin09g01120 713 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc-binding loop region of homing endonuclease + Zinc finger, C2H2-like Bcin09g01130 389 P-loop containing nucleoside triphosphate hydrolase Bcin09g01140 439 SNF2-related + P-loop containing nucleoside triphosphate hydrolase Bcin09g01150 574 Cellulose-binding domain, fungal Bcin09g01160 859 Bcin09g01170 1220 Zinc finger, CCCH-type Bcin09g01180 706 Sec1-like protein + Sec1-like, domain 2 Bcin09g01190 601 Protease Peptidase S8/S53 domain + Proteinase inhibitor, propeptide + Peptidase S53, propeptide + Peptidase S8, subtilisin, Ser-active site + Sedolisin domain Bcin09g01200 164 Effector(V2)|Effector(V1) "Bcltp1, similar to yeast LTP1, Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine [Source:SGD;Acc:S000006277]" Bcin09g01210 930 yes BcCHSI, Class I chitin synthase Bcin09g01220 435 Butirosin biosynthesis, BtrG-like Bcin09g01230 350 Protease Alpha/Beta hydrolase fold Bcin09g01240 1810 Phox homologous domain + Phospholipase D/Transphosphatidylase + Phospholipase D family + Phospholipase D1/D2 + Phospholipase D-like domain Bcin09g01250 283 "Bccat5, similar to yeast CAT5, Protein required for ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; required for gluconeogenic gene activation [Source:SGD;Acc:S000005651]" Bcin09g01260 610 "Bcrtf1, similar to yeast RTF1, Subunit of RNAPII-associated chromatin remodeling Paf1 complex; regulates gene expression by directing cotranscriptional histone modification, influences transcription and chromatin structure through several independent functional domains; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay [Source:SGD;Acc:S000003213]" Bcin09g01270 283 GNAT domain + Acyl-CoA N-acyltransferase Bcin09g01280 362 Bcin09g01290 528 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin09g01300 889 CAZy : GTnc Glycosyltransferase 2-like + Nucleotide-diphospho-sugar transferases Bcin09g01310 727 yes CAZy : GH37Energy Bctre1, Neutraltrehalasegene Bcin09g01320 548 Bcicl1, isocitrate lyase Bcin09g01330 1055 "Bcprp24, similar to yeast PRP24, Splicing factor that reanneals snRNPs during spliceosome recycling; reanneals U4 and U6 snRNPs [Source:SGD;Acc:S000004881]" Bcin09g01340 328 Ribosomal protein L22/L17 + Ribosomal protein L22, bacterial/chloroplast-type Bcin09g01350 462 Molybdate transporter 1/2 Bcin09g01360 1373 "Bcmrc1, similar to yeast MRC1, S-phase checkpoint protein required for DNA replication; couples DNA helicase and DNA polymerase; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; with Hog1p defines a novel S-phase checkpoint that permits eukaryotic cells to prevent conflicts between DNA replication and transcription; protects uncapped telomeres; degradation via Dia2p help cells resume cell cycle [Source:SGD;Acc:S000000566]" Bcin09g01370 417 Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type Bcin09g01380 285 Bcin09g01390 536 "Bcutp15, similar to yeast UTP15, Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA [Source:SGD;Acc:S000004699]" Bcin09g01400 371 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Tetratricopeptide repeat + Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site + Cyclophilin-type peptidyl-prolyl cis-trans isomerase + Cyclophilin-like domain Bcin09g01410 154 Effector(V2)|Effector(V1) "Bcdtd1, similar to yeast DTD1, D-Tyr-tRNA(Tyr) deacylase; functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes [Source:SGD;Acc:S000002378]" Bcin09g01420 656 CCR4-Not complex component, Not N-terminal domain + NOT2/NOT3/NOT5 Bcin09g01430 407 Cys2His2 transcription factor Bcin09g01440 1344 C2 domain + Ras GTPase-activating protein + Rho GTPase activation protein + Ras GTPase-activating protein, conserved site Bcin09g01450 384 Bcin09g01460 202 Ribosomal protein L20, mitochondrial Bcin09g01470 467 Bcin09g01480 184 Effector(V2)|Effector(V1) Bcin09g01490 181 Bcin09g01500 600 Cys2His2 transcription factor Zinc finger, C2H2 Bcin09g01510 166 Effector(V1) Bcin09g01520 1115 "Bcefr3, similar to yeast EFR3, Protein required for Stt4-containing PI kinase complex localization; required for Stt4-containing phosphoinositide (PI) kinase patch assembly at the plasma membrane; recruited to the plasma membrane via a conserved basic patch near its N-terminus; exhibits synthetic lethal genetic interactions with PHO85; has sequence similarity to the Drosophila rolling blackout (RBO) gene [Source:SGD;Acc:S000004825]" Bcin09g01530 347 "Bctes1, similar to yeast TES1, Peroxisomal acyl-CoA thioesterase; likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids [Source:SGD;Acc:S000003780]" Bcin09g01540 673 Heterokaryon incompatibility Bcin09g01550 169 Effector(V1) "Bcarc19, similar to yeast ARC19, Subunit of the ARP2/3 complex; ARP2/3 is required for the motility and integrity of cortical actin patches [Source:SGD;Acc:S000001496]" Bcin09g01560 624 Protease "Bcubp6, similar to yeast UBP6, Ubiquitin-specific protease; situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; negatively regulates degradation of ubiquitinated proteins by the proteasome; works in opposition to Hul5p polyubiquitin elongation activity; mutant has aneuploidy tolerance [Source:SGD;Acc:S000001906]" Bcin09g01570 314 Methyltransferase domain + S-adenosyl-L-methionine-dependent methyltransferase Bcin09g01580 756 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin09g01590 2046 Ankyrin repeat + NACHT nucleoside triphosphatase + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin09g01610 536 Transporter//SignalP-noTM Bchex4, Similar to MFS sugar transporter Bcin09g01620 677 yes Bccry2, Cryptochrome-like, potential blue light sensor Bcin09g01640 725 "Bckin3, similar to yeast KIN3, Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071]" Bcin09g01650 647 BTB/POZ-like + Ankyrin repeat + BTB/POZ fold + Ankyrin repeat-containing domain Bcin09g01660 134 Effector(V2)|Effector(V1) Bcin09g01670 459 Bcin09g01680 192 GNAT domain + Acyl-CoA N-acyltransferase Bcin09g01690 196 GNAT domain + Acyl-CoA N-acyltransferase Bcin09g01700 321 "Bcfmp10, similar to yeast FMP10, Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000000984]" Bcin09g01710 143 SignalP-noTM//Effector(V1) Bcin09g01720 1480 "Bcmtc5, similar to yeast MTC5, Subunit of the SEA (Seh1-associated) complex; SEA is a coatomer-related complex that associates dynamically with the vacuole; has N-terminal WD-40 repeats and a C-terminal RING motif; mtc5 is synthetically sick with cdc13-1; relative distribution to vacuolar membrane punctae decreases upon DNA replication stress [Source:SGD;Acc:S000002535]" Bcin09g01730 150 Effector(V1) Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like + Ubiquitin-conjugating enzyme, active site Bcin09g01740 596 Transporter Sugar transporter, conserved site + Fungal trichothecene efflux pump + Major facilitator superfamily domain Bcin09g01750 599 Bcin09g01760 528 Fucose-specific lectin Bcin09g01770 343 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger, C2H2-like Bcin09g01780 228 Effector(V2)|Effector(V1) Zinc finger, MYND-type Bcin09g01790 293 Bcin09g01800 329 yes CAZy : CE3PCW hemicellulose//SignalP-noTM BcXyl1, xylanase Bcin09g01810 471 Protein kinase domain + Protein kinase-like domain Bcin09g01820 242 Protease//Effector(V2) Phospholipase/carboxylesterase/thioesterase + Alpha/Beta hydrolase fold Bcin09g01830 507 IMD/I-BAR domain Bcin09g01840 448 Bcin09g01850 141 Effector(V1) Thioredoxin-like fold + Protein of unknown function DUF1687, fungi Bcin09g01860 1169 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin09g01870 353 Effector(V2)|Effector(V1) Zinc finger, RING-type + Zinc finger, C6HC-type + E3 ubiquitin ligase RBR family Bcin09g01880 154 Effector(V2)|Effector(V1) Bcin09g01890 76 Effector(V2)|Effector(V1) Bcin09g01900 449 Bcin09g01910 765 Protein kinase domain + Protein kinase-like domain Bcin09g01920 177 EF-hand domain + EF-hand domain pair + EF-Hand 1, calcium-binding site Bcin09g01930 552 "Bcpdh1, similar to yeast PDH1, Putative 2-methylcitrate dehydratase; mitochondrial protein that participates in respiration; induced by diauxic shift; homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate [Source:SGD;Acc:S000006206]" Bcin09g01940 727 Bcin09g01950 302 Transcription elognation factor Eaf, N-terminal Bcin09g01960 590 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin09g01970 474 CAZy : GH16FCW Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin09g01980 876 CAZy : GTnc Glycosyltransferase 2-like + Nucleotide-diphospho-sugar transferases Bcin09g01990 598 Amidase + Amidase signature domain Bcin09g02000 541 Protease "Bchis7, similar to yeast HIS7, Imidazole glycerol phosphate synthase; glutamine amidotransferase:cyclase that catalyzes the fifth step of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor [Source:SGD;Acc:S000000452]" Bcin09g02010 345 Molybdenum cofactor sulfurase, C-terminal + MOSC, N-terminal beta barrel + Pyruvate kinase-like, insert domain Bcin09g02020 694 Protein kinase domain + AGC-kinase, C-terminal + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site + Protein kinase, C-terminal Bcin09g02030 88 Bcin09g02040 1087 AMP-dependent synthetase/ligase + Acyl carrier protein-like + Male sterility, NAD-binding + NAD(P)-binding domain + Polyketide synthase, phosphopantetheine-binding domain Bcin09g02050 604 Bclcc10, Laccase Bcin09g02060 227 Bcin09g02070 452 CAZy : GH76FCW //SignalP-noTM Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase + Mannan endo-1,6-alpha-mannosidase Bcin09g02080 584 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin09g02090 122 Effector(V2)|Effector(V1) Synaptobrevin + Synaptobrevin/Vesicle-associated membrane protein Bcin09g02100 894 "Bcarg5, similar to yeast ARG5,6, Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase; N-acetyl-L-glutamate kinase (NAGK) catalyzes the 2nd and N-acetyl-gamma-glutamyl-phosphate reductase (NAGSA), the 3rd step in arginine biosynthesis; synthesized as a precursor which is processed in the mitochondrion to yield mature NAGK and NAGSA; enzymes form a metabolon complex with Arg2p; NAGK C-terminal domain stabilizes the enzymes, slows catalysis and is involved in feed-back inhibition by arginine [Source:SGD;Acc:S000000871]" Bcin09g02120 388 Bcin09g02130 346 Bcin09g02140 334 Bcin09g02150 118 Bcin09g02160 251 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin09g02170 382 "Bcdim1, similar to yeast DIM1, Essential 18S rRNA dimethylase (dimethyladenosine transferase); responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18S rRNA, part of 90S and 40S pre-particles in nucleolus, involved in pre-ribosomal RNA processing [Source:SGD;Acc:S000006187]" Bcin09g02180 809 "Bctsr1, similar to yeast TSR1, Protein required for processing of 20S pre-rRNA in the cytoplasm; associates with pre-40S ribosomal particles; inhibits the premature association of 60S subunits with assembling 40S subunits in the cytoplasm; similar to Bms1p; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000002218]" Bcin09g02190 553 "Bcutp7, similar to yeast UTP7, Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA [Source:SGD;Acc:S000000884]" Bcin09g02200 268 Effector(V1) Bcpio1, Gene with a peak of expression during the Outset of colonization Bcin09g02210 430 "Bcade12, similar to yeast ADE12, Adenylosuccinate synthase; catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence [Source:SGD;Acc:S000005164]" Bcin09g02220 474 Cytochrome P450 + Cytochrome P450, E-class, group II + Cytochrome P450, E-class, CYP52 Bcin09g02230 586 Transporter Fungal trichothecene efflux pump + Major facilitator superfamily domain Bcin09g02240 345 Oxidoreductase, N-terminal + NAD(P)-binding domain Bcin09g02250 363 Bcin09g02260 320 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa PLC-like phosphodiesterase, TIM beta/alpha-barrel domain Bcin09g02270 195 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Extracellular membrane protein, CFEM domain Bcin09g02280 419 HD/PDEase domain + HD domain + Clr5 domain Bcin09g02290 366 Kynurenine formamidase Bcin09g02300 337 Phosphotransferase KptA/Tpt1 Bcin09g02310 366 Protease "Bcoma1, similar to yeast OMA1, Metalloendopeptidase of the mitochondrial inner membrane; important for adaptive responses to various homeostatic insults and preservation of normal mitochondrial function under damage-eliciting conditions; involved in turnover of membrane-embedded proteins; mediates degradation of Cox1p in coa2 mutant cells; member of a family of predicted membrane-bound metallopeptidases in prokaryotes and higher eukaryotes [Source:SGD;Acc:S000001795]" Bcin09g02320 446 yes BcKDC, Kelch domain-containing protein Bcin09g02330 188 Effector(V2)|Effector(V1) CMP/dCMP deaminase, zinc-binding + Cytidine deaminase-like Bcin09g02340 565 SignalP-TM Cytochrome P450 + Cytochrome P450, E-class, group I Bcin09g02350 563 Protease Peptidase S10, serine carboxypeptidase + Peptidase S10, serine carboxypeptidase, active site + Alpha/Beta hydrolase fold + Serine carboxypeptidases, histidine active site Bcin09g02360 240 "Bcups1, similar to yeast UPS1, Phosphatidic acid transfer protein; plays a role in phospholipid metabolism by transporting phosphatidic acid from the outer to the inner mitochondrial membrane; localizes to the mitochondrial intermembrane space; null mutant has altered cardiolipin and phosphatidic acid levels; ortholog of human PRELI [Source:SGD;Acc:S000004183]" Bcin09g02370 474 "Bcwrs1, similar to yeast WRS1, Cytoplasmic tryptophanyl-tRNA synthetase; aminoacylates tryptophanyl-tRNA [Source:SGD;Acc:S000005457]" Bcin09g02380 351 Bcin09g02390 413 yes Signaling pathway Bmp3, MAP kinase Bcin09g02400 294 "Bcabz2, similar to yeast ABZ2, Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase); catalyzes the third step in para-aminobenzoic acid biosynthesis; involved in folic acid biosynthesis [Source:SGD;Acc:S000004902]" Bcin09g02410 421 SignalP-noTM Bcin09g02420 622 Mitochondrial outer membrane translocase complex, subunit Tom70 + Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Tetratricopeptide TPR2 + Tetratricopeptide repeat Bcin09g02430 908 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin09g02440 641 Cys2His2 transcription factor Bcin09g02450 434 Tetratricopeptide-like helical domain Bcin09g02460 131 Effector(V2)|Effector(V1) Cytochrome b5-like heme/steroid binding domain Bcin09g02470 339 Bcin09g02480 641 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin09g02490 106 Effector(V2) Ribosomal protein L44e + Zinc-binding ribosomal protein Bcin09g02500 327 RNA ligase/cyclic nucleotide phosphodiesterase Bcin09g02510 2478 Zinc finger, RING/FYVE/PHD-type + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase + S-adenosyl-L-methionine-dependent methyltransferase Bcin09g02520 121 Bcin09g02530 417 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin09g02540 594 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin09g02550 554 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin09g02560 1131 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin09g02570 208 Effector(V1) Bcin09g02580 461 "Bcrad28, similar to yeast RAD28, Protein involved in DNA repair; related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair [Source:SGD;Acc:S000002437]" Bcin09g02590 259 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin09g02600 242 "Bcmge1, similar to yeast MGE1, Mitochondrial matrix cochaperone; nucleotide release factor for Ssc1p in protein translocation and folding; also acts as cochaperone for Ssq1p in folding of Fe-S cluster proteins; acts as oxidative sensor to regulate mitochondrial Ssc1p; in presence of oxidative stress, dimeric Mge1p becomes a monomer and unable to regulate Ssc1p function; homolog of E. coli GrpE and human Mge1 (GRPEL1), which also responds to oxidative stress [Source:SGD;Acc:S000005758]" Bcin09g02610 343 Bcin09g02620 1357 Bcin09g02630 552 K Homology domain + K Homology domain, type 1 Bcin09g02640 804 CAZy : GH3PCW/FCW //SignalP-noTM//Early secretome Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Glycoside hydrolase, family 3, active site + Fibronectin type III-like domain Bcin09g02650 830 Reduced growth phenotype protein 1 Bcin09g02660 220 Effector(V2)|Effector(V1) "Bcmob1, similar to yeast MOB1, Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex; relocalizes from cytoplasm to the nuclear periphery upon DNA replication stress [Source:SGD;Acc:S000001368]" Bcin09g02670 226 Effector(V2)|Effector(V1) "Bcatp5, similar to yeast ATP5, Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein); phosphorylated [Source:SGD;Acc:S000002706]" Bcin09g02680 1033 CAZy : GHnc Glycoside hydrolase, family 63 + Six-hairpin glycosidase-like + Glycosyl hydrolase family 63, C-terminal Bcin09g02690 734 Kinesin motor domain + P-loop containing nucleoside triphosphate hydrolase Bcin09g02700 465 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin09g02710 793 CAZy : GT1 UDP-glucuronosyl/UDP-glucosyltransferase + Glycosyltransferase family 28, N-terminal domain Bcin09g02720 830 CAZy : GH78PCW pectin//SignalP-noTM Bacterial alpha-L-rhamnosidase + Six-hairpin glycosidase-like Bcin09g02730 759 Monooxygenase, FAD-binding + Acetoacetate decarboxylase beta barrel domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin09g02740 597 Bcin09g02750 168 Effector(V1) Bcin09g02760 310 Transporter Bcucp1, Uncoupling protein 1 Bcin09g02770 492 "Bcmsf1, similar to yeast MSF1, Mitochondrial phenylalanyl-tRNA synthetase; active as a monomer, unlike the cytoplasmic subunit which is active as a dimer complexed to a beta subunit dimer; similar to the alpha subunit of E. coli phenylalanyl-tRNA synthetase [Source:SGD;Acc:S000006251]" Bcin09g02780 114 Effector(V1) Bcin09g02790 668 AMP-dependent synthetase/ligase + Acetate-CoA ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain + Acetyl-coenzyme A synthetase, N-terminal domain Bcin09g02800 804 Protease//SignalP-noTM Peptidase M12B, ADAM/reprolysin + Blood coagulation inhibitor, Disintegrin + Metallopeptidase, catalytic domain Bcin09g02810 336 "Bcrpb3, similar to yeast RPB3, RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit [Source:SGD;Acc:S000001283]" Bcin09g02820 255 yes Signaling pathway Bcrcn1, Regulator of calcineurin Bcin09g02830 481 Domain of unknown function DUF2236 Bcin09g02840 353 "Bcrrg9, similar to yeast RRG9, Protein of unknown function; null mutant lacks mitochondrial DNA and cannot grow on glycerol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000005157]" Bcin09g02850 1052 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site Bcin09g02860 458 "Bcrvb1, similar to yeast RVB1, ATP-dependent DNA helicase, also known as pontin; member of the AAA+ and RuvB-like protein families; similar to Rvb2p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly [Source:SGD;Acc:S000002598]" Bcin09g02870 800 HMG (high mobility group) transcription factor "Bcrox1, similar to yeast ROX1, Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance [Source:SGD;Acc:S000006269]" Bcin09g02880 622 Bcin09g02890 221 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Protein of unknown function DUF3455 Bcin09g02900 537 Major facilitator superfamily + Major facilitator superfamily domain Bcin09g02910 613 Protease Gamma-glutamyltranspeptidase + Nucleophile aminohydrolases, N-terminal Bcin09g02920 429 "Bcmrf1, similar to yeast MRF1, Mitochondrial translation release factor; involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability [Source:SGD;Acc:S000003111]" Bcin09g02930 432 yes Protease Bcap1, Aspartic proteinase Bcin09g02940 213 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin09g02950 999 AAA+ ATPase domain + ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin09g02960 779 Heterokaryon incompatibility Bcin09g02970 114 Effector(V1) Bcin09g02980 2171 Methyl methanesulphonate-sensitivity protein 22 Bcin09g02990 349 Bcin09g03000 152 Effector(V1) Bcin09g03010 1107 Bcin09g03020 493 Tetratricopeptide-like helical domain + Tetratricopeptide, SHNi-TPR domain + Tetratricopeptide repeat Bcin09g03030 781 "Bcdpb2, similar to yeast DPB2, Second largest subunit of DNA polymerase II (DNA polymerase epsilon); required for maintenance of fidelity of chromosomal replication; essential motif in C-terminus is required for formation of the four-subunit Pol epsilon; expression peaks at the G1/S phase boundary; Cdc28p substrate [Source:SGD;Acc:S000006379]" Bcin09g03040 580 "Bcgyp1, similar to yeast GYP1, Cis-golgi GTPase-activating protein (GAP) for yeast Rabs; the Rab family members are Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion [Source:SGD;Acc:S000005596]" Bcin09g03050 619 "Bchrp1, similar to yeast HRP1, Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability [Source:SGD;Acc:S000005483]" Bcin09g03060 348 Bcin09g03070 286 S-adenosyl-L-methionine-dependent methyltransferase Bcin09g03080 424 Bcin09g03090 392 Phosphatidic acid phosphatase type 2/haloperoxidase Bcin09g03100 608 Protease "Bcaip1, similar to yeast AIP1, Actin cortical patch component; interacts with the actin depolymerizing factor cofilin; inhibits elongation of aged ADP-actin filaments decorated with cofilin to maintain a high level of assembly-competent actin species; required to restrict cofilin localization to cortical patches; putative regulator of cytokinesis; contains WD repeats; protein increases in abundance and relocalizes from cytoplasm to plasma membrane upon DNA replication stress [Source:SGD;Acc:S000004698]" Bcin09g03110 365 BTB/POZ-like + BTB/POZ fold Bcin09g03120 260 Effector(V2)|Effector(V1) Bcin09g03130 313 Phytanoyl-CoA dioxygenase Bcin09g03140 200 Bcin09g03150 465 Protein of unknown function DUF2373 Bcin09g03160 254 Protease//Effector(V2)|Effector(V1) "Bcscl1, similar to yeast SCL1, Alpha 1 subunit of the 20S proteasome; involved in the degradation of ubiquitinated substrates; 20S proteasome is the core complex of the 26S proteasome; essential for growth; detected in the mitochondria [Source:SGD;Acc:S000002979]" Bcin09g03170 181 Effector(V1) Bcin09g03180 169 Uncharacterised protein family UPF0546 Bcin09g03190 1118 "Bcinn1, similar to yeast INN1, Essential protein that associates with contractile actomyosin ring; required for ingression of the plasma membrane into the bud neck during cytokinesis; C2 domain, a membrane targeting module, is required for function; activates chitin synthase activity of Chs2p during cytokinesis [Source:SGD;Acc:S000005096]" Bcin09g03200 938 "Bcspc98, similar to yeast SPC98, Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque [Source:SGD;Acc:S000005070]" Bcin09g03210 455 "Bchfi1, similar to yeast HFI1, Adaptor protein required for structural integrity of the SAGA complex; a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions [Source:SGD;Acc:S000006175]" Bcin09g03220 539 "Bcfum1, similar to yeast FUM1, Fumarase; converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt; phosphorylated in mitochondria [Source:SGD;Acc:S000006183]" Bcin09g03230 427 Fatty acid desaturase, type 1 Bcin09g03240 588 SignalP-noTM GDP-fucose protein O-fucosyltransferase Bcin09g03250 332 Bcin09g03260 447 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin09g03270 1252 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site + Fungal kinase associated-1 domain Bcin09g03280 1131 RecF/RecN/SMC, N-terminal + Structural maintenance of chromosomes protein 5 + P-loop containing nucleoside triphosphate hydrolase Bcin09g03290 428 Bcin09g03300 144 Effector(V1) Bcin09g03310 427 Zinc finger, CCCH-type Bcin09g03320 342 SignalP-noTM Bcin09g03330 650 Cyclin PHO80-like Bcin09g03340 298 WW domain binding protein 11 + H/ACA ribonucleoprotein complex, subunit Gar1 Bcin09g03350 236 Bcin09g03360 328 Bcin09g03370 884 "Bcpop1, similar to yeast POP1, Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; binds to the RPR1 RNA subunit in RNase P [Source:SGD;Acc:S000005165]" Bcin09g03380 295 Bcin09g03390 767 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + Ketopantoate reductase, N-terminal domain + Ketopantoate reductase, C-terminal domain + NAD(P)-binding domain Bcin09g03400 276 Bcin09g03410 444 "Bcsub2, similar to yeast SUB2, Component of the TREX complex required for nuclear mRNA export; member of the DEAD-box RNA helicase superfamily and is involved in early and late steps of spliceosome assembly; homolog of the human splicing factor hUAP56; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000002242]" Bcin09g03420 171 Effector(V2)|Effector(V1) RNAse P, Rpr2/Rpp21 subunit Bcin09g03430 594 SignalP-noTM Amidase signature domain Bcin09g03440 345 Protein of unknown function DUF92, TMEM19 Bcin09g03450 1240 Bcin09g03460 155 Effector(V2)|Effector(V1) Tetratricopeptide-like helical domain Bcin09g03470 842 Cys2His2 transcription factor Ankyrin repeat + Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like + Ankyrin repeat-containing domain Bcin09g03480 116 Cys2His2 transcription factor//Effector(V2)|Effector(V1) Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin09g03490 894 CAZy : GH16FCW //SignalP-noTM Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin09g03500 154 Effector(V2)|Effector(V1) Bcin09g03510 689 Heterokaryon incompatibility Bcin09g03520 212 Effector(V1) Bcin09g03530 223 Effector(V2)|Effector(V1) Bcin09g03540 623 AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain Bcin09g03550 145 Effector(V1) Ribosomal protein L14 + KOW + Translation protein SH3-like domain + Ribosomal protein L2 domain 2 Bcin09g03560 212 "Bcegd2, similar to yeast EGD2, Alpha subunit of the nascent polypeptide-associated complex (NAC); involved in protein sorting and translocation; associated with cytoplasmic ribosomes [Source:SGD;Acc:S000001236]" Bcin09g03570 174 Effector(V1) "Bcatp7, similar to yeast ATP7, Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis [Source:SGD;Acc:S000001499]" Bcin09g03580 387 Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin09g03590 396 Bcin09g03600 598 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB Bcin09g03610 822 Bcin09g03620 276 Bcin09g03630 317 NmrA-like domain + NAD(P)-binding domain Bcin09g03640 548 HhH-GPD domain + DNA glycosylase + Helix-turn-helix, base-excision DNA repair, C-terminal Bcin09g03650 236 Effector(V2)|Effector(V1) GNAT domain + Acyl-CoA N-acyltransferase Bcin09g03660 375 Bcin09g03670 543 Transporter Amino acid/polyamine transporter I Bcin09g03680 610 "Bcmsc7, similar to yeast MSC7, Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids [Source:SGD;Acc:S000001081]" Bcin09g03690 417 Bcin09g03700 260 SignalP-noTM Bcin09g03710 589 Protease "Bcade4, similar to yeast ADE4, Phosphoribosylpyrophosphate amidotransferase (PRPPAT); catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway; also known as amidophosphoribosyltransferase [Source:SGD;Acc:S000004915]" Bcin09g03720 535 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin09g03730 187 Mpv17/PMP22 Bcin09g03750 173 Effector(V2)|Effector(V1) Bcin09g03760 415 SignalP-TM Bcprd9, Peroxidase 9 Bcin09g03770 136 Bcin09g03780 114 Bcin09g03790 281 BTB/POZ-like + BTB/POZ fold Bcin09g03800 108 Effector(V2)|Effector(V1) Dimeric alpha-beta barrel + Stress responsive alpha-beta barrel Bcin09g03810 263 Protease//Effector(V2)|Effector(V1) Dienelactone hydrolase + Alpha/Beta hydrolase fold Bcin09g03820 645 Effector(V2)|Effector(V1) SH3 domain Bcin09g03830 188 Bcin09g03840 261 Effector(V2) Zinc finger, CCHC-type Bcin09g03850 363 Transaldolase + Aldolase-type TIM barrel + Transaldolase, active site Bcin09g03860 607 Transporter//SignalP-noTM Major facilitator superfamily + Major facilitator superfamily domain Bcin09g03870 805 Dynamin central domain + Dynamin, GTPase domain + GTPase effector domain, GED + Dynamin superfamily + P-loop containing nucleoside triphosphate hydrolase + Dynamin-type guanine nucleotide-binding (G) domain Bcin09g03880 537 SignalP-TM Vacuolar protein sorting-associated protein 62 Bcin09g03890 125 Cbp4 Bcin09g03900 1104 Sel1-like + Tetratricopeptide-like helical domain Bcin09g03910 201 Mitochondrial pyruvate carrier Bcin09g03920 92 Effector(V2)|Effector(V1) Ribosomal protein/NADH dehydrogenase domain + Thioredoxin-like fold + NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2 Bcin09g03930 239 Effector(V2)|Effector(V1) Bcprx8, Peroxiredoxin Bcin09g03940 154 Early secretome Protein of unknown function DUF1348 + NTF2-like domain Bcin09g03950 442 RGS domain Bcin09g03960 557 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin09g03970 329 Intradiol ring-cleavage dioxygenase, C-terminal + Catechol dioxygenase, N-terminal + Intradiol ring-cleavage dioxygenase, core Bcin09g03980 431 Adenosine deaminase/editase Bcin09g03990 636 "Bcspp1, similar to yeast SPP1, Subunit of COMPASS (Set1C); a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; interacts with Orc2p; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006059]" Bcin09g04000 343 Cys2His2 transcription factor BcmtfA, Cys2His2 transcription factor Bcin09g04010 136 Effector(V1) Bcin09g04020 430 CAZy : CEnc //SignalP-noTM GDSL lipase/esterase + SGNH hydrolase-type esterase domain Bcin09g04030 176 Effector(V1) Bcin09g04040 451 RelA/SpoT Bcin09g04050 482 "Bcmrs6, similar to yeast MRS6, Rab escort protein; forms a complex with the Ras-like small GTPase Ypt1p that is required for the prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p); sequence similarity to mammalian choroideraemia gene; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000005897]" Bcin09g04060 934 "Bcfre7, similar to yeast FRE7, Putative ferric reductase with similarity to Fre2p; expression induced by low copper levels [Source:SGD;Acc:S000005512]" Bcin09g04070 344 Exoribonuclease, phosphorolytic domain 1 + Exoribonuclease, phosphorolytic domain 2 + Ribosomal protein S5 domain 2-type fold + Exosome complex component Rrp43 Bcin09g04080 403 Bcin09g04090 287 Bcin09g04100 523 Pal1 cell morphology Bcin09g04110 234 "Bcsoh1, similar to yeast SOH1, Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance; conserved with other metazoan MED31 subunits [Source:SGD;Acc:S000003095]" Bcin09g04120 216 Effector(V2)|Effector(V1) "Bcrpc11, similar to yeast RPC11, RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription; homologous to TFIIS [Source:SGD;Acc:S000002452]" Bcin09g04130 220 Ankyrin repeat + Ankyrin repeat-containing domain Bcin09g04140 765 Heterokaryon incompatibility Bcin09g04150 437 Thaumatin Bcin09g04160 740 Heat shock protein 70 family Bcin09g04170 559 yes Bcglk, Glucokinase Bcin09g04180 517 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin09g04190 504 Major facilitator superfamily + Major facilitator superfamily domain Bcin09g04200 698 Bcin09g04210 512 Alginate lyase domain + Chondroitin AC/alginate lyase Bcin09g04220 410 SignalP-noTM Bcin09g04230 138 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin09g04240 567 Carbohydrate kinase, FGGY + Glycerol kinase + Carbohydrate kinase, FGGY, conserved site + Carbohydrate kinase, FGGY, N-terminal + Carbohydrate kinase, FGGY, C-terminal Bcin09g04250 459 yes Bcaqp9, Aquaporin Bcin09g04260 145 Effector(V2)|Effector(V1) Bcin09g04270 172 Effector(V1) Bcin09g04280 328 Bcin09g04290 324 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit Bcin09g04300 292 "Bcsec17, similar to yeast SEC17, Alpha-SNAP cochaperone; SNARE-complex adaptor for Sec18 (NSF) during the disassembly of postfusion cis-SNARE complexes; stimulates the ATPase activity of Sec18p; peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, and autophagy; similar to mammalian alpha-SNAP [Source:SGD;Acc:S000000146]" Bcin09g04310 711 Protein of unknown function DUF726 + Alpha/Beta hydrolase fold Bcin09g04320 398 SignalP-noTM Ureohydrolase + Ureohydrolase, manganese-binding site + Ureohydrolase domain Bcin09g04330 1022 Bcin09g04340 115 Effector(V1) Uncharacterised protein family UPF0390 Bcin09g04350 265 Bcin09g04360 142 Effector(V1) Bcin09g04370 348 Oxoglutarate/iron-dependent dioxygenase + Isopenicillin N synthase-like Bcin09g04380 311 Phytanoyl-CoA dioxygenase Bcin09g04390 198 RmlC-like cupin domain + Cupin 2, conserved barrel + RmlC-like jelly roll fold Bcin09g04400 315 Bccat7, Catalase Bcin09g04410 636 CAZy : CBM32,AA5 //SignalP-noTM Coagulation factor 5/8 C-terminal type domain + Kelch repeat type 1 + Galactose-binding domain-like + Galactose oxidase/kelch, beta-propeller + Immunoglobulin-like fold + Immunoglobulin E-set + Domain of unknown function DUF1929 + Galactose oxidase, beta-propeller Bcin09g04420 1118 SignalP-noTM Bcgo3, Glyoxal oxidase Bcin09g04430 573 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin09g04440 637 CAZy : GH51PCW hemicellulose or pectin//SignalP-noTM Alpha-L-arabinofuranosidase, C-terminal + Glycoside hydrolase superfamily Bcin09g04450 417 Protease Beta-lactamase-related + Beta-lactamase/transpeptidase-like Bcin09g04460 503 Major facilitator superfamily + Major facilitator superfamily domain Bcin09g04470 217 Protein of unknown function DUF985 + RmlC-like cupin domain + RmlC-like jelly roll fold Bcin09g04480 683 "Bcage2, similar to yeast AGE2, ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector; involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif [Source:SGD;Acc:S000001306]" Bcin09g04490 1004 CAZy : GH65Energy //SignalP-noTM//Early secretome Glycoside hydrolase, family 65, central catalytic + Glycoside hydrolase, family 65, N-terminal + Six-hairpin glycosidase-like + Galactose-binding domain-like + Galactose mutarotase-like domain + Six-hairpin glycosidase Bcin09g04500 387 S-adenosyl-L-methionine-dependent methyltransferase Bcin09g04510 498 Pyridoxal phosphate-dependent decarboxylase + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin09g04520 580 Flavin monooxygenase FMO + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin09g04530 166 Effector(V1) Major facilitator superfamily + Major facilitator superfamily domain Bcin09g04540 470 Bcin09g04550 1188 yes Bcwee1, Kinase Bcin09g04560 340 NmrA-like domain + NAD(P)-binding domain Bcin09g04570 623 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin09g04580 849 "Bcvac7, similar to yeast VAC7, Integral vacuolar membrane protein; involved in vacuole inheritance and morphology; activates Fab1p kinase activity under basal conditions and also after hyperosmotic shock [Source:SGD;Acc:S000004999]" Bcin09g04590 763 Dynamin central domain + Dynamin, GTPase domain + GTPase effector domain, GED + Dynamin superfamily + P-loop containing nucleoside triphosphate hydrolase + Dynamin-type guanine nucleotide-binding (G) domain Bcin09g04600 421 Bcin09g04610 513 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin09g04620 104 Heat shock protein 9/12 + Heat shock protein, 9/12, fungi Bcin09g04630 927 "Bcprp6, similar to yeast PRP6, Splicing factor; component of the U4/U6-U5 snRNP complex [Source:SGD;Acc:S000000259]" Bcin09g04640 306 Bcin09g04650 217 "Bcrsm18, similar to yeast RSM18, Mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S18 ribosomal protein [Source:SGD;Acc:S000000852]" Bcin09g04660 186 Effector(V1) Ribosomal protein S4/S9, N-terminal + RNA-binding S4 domain + Ribosomal protein S4/S9 Bcin09g04670 314 SignalP-TM Bcin09g04680 279 Bcin09g04690 228 Effector(V1) Bcin09g04700 113 Effector(V2)|Effector(V1) Bcin09g04710 1106 Domain of unknown function DUF3824 Bcin09g04720 408 "Bcdcd1, similar to yeast DCD1, Deoxycytidine monophosphate (dCMP) deaminase; involved in dUMP and dTMP biosynthesis; expression is NOT cell cycle regulated [Source:SGD;Acc:S000001187]" Bcin09g04730 699 yes Bcatg7, Ubiquitin-like protein-activating enzyme, in autophagy process Bcin09g04740 802 Bcin09g04750 237 Bcin09g04760 131 Effector(V2)|Effector(V1) Bcin09g04770 181 Effector(V1) Bcin09g04780 371 Bcin09g04790 464 CAZy : GH39PCW hemicellulose//SignalP-noTM//Early secretome Glycoside hydrolase, family 39 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin09g04800 159 Bcin09g04810 360 Bcin09g04820 346 CAZy : GH16FCW //SignalP-noTM Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin09g04830 602 Bclcc3, Laccase/ Multicopper oxidase Bcin09g04840 200 Effector(V2)|Effector(V1) Zinc finger, MYND-type + Tetratricopeptide-like helical domain Bcin09g04850 961 CAZy : GH3PCW/FCW Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Fibronectin type III-like domain Bcin09g04860 228 Effector(V2)|Effector(V1) Fungal STAND N-terminal Goodbye domain Bcin09g04870 273 Bcin09g04880 390 Bcin09g04890 974 Bcin09g04900 681 Sodium/solute symporter Bcin09g04910 137 Effector(V1) Dynein light chain-related Bcin09g04920 348 "Bcipi1, similar to yeast IPI1, Component of the Rix1 complex and possibly pre-replicative complexes; required for processing of ITS2 sequences from 35S pre-rRNA; component of the pre-60S ribosomal particle with the dynein-related AAA-type ATPase Mdn1p; required for pre-replicative complex (pre-RC) formation and maintenance during DNA replication licensing; relocalizes to the cytosol in response to hypoxia; essential gene [Source:SGD;Acc:S000001127]" Bcin09g04930 542 Domain of unknown function DUF262 Bcin09g04940 270 SignalP-noTM FMN-binding split barrel Bcin09g04950 62 Effector(V1) Ribosomal protein S30 Bcin09g04960 989 GATA zinc finger transcription factor BcareA, GATA zinc finger transcription factor Bcin09g04970 399 Concanavalin A-like lectin/glucanase domain Bcin09g04980 113 Effector(V1) DASH complex subunit Hsk3 like Bcin09g04990 270 Effector(V2)|Effector(V1) Bcin09g05000 231 GNAT domain + Acyl-CoA N-acyltransferase Bcin09g05010 483 yes SignalP-noTM Bcflp2, Fasciclin-like protein Bcin09g05020 557 "Bcgad1, similar to yeast GAD1, Glutamate decarboxylase; converts glutamate into gamma-aminobutyric acid (GABA) during glutamate catabolism; involved in response to oxidative stress [Source:SGD;Acc:S000004862]" Bcin09g05030 660 "Bcsrp101, similar to yeast SRP101, Signal recognition particle (SRP) receptor alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with the beta subunit, Srp102p [Source:SGD;Acc:S000002700]" Bcin09g05040 324 "Bcyif1, similar to yeast YIF1, Integral membrane protein; required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles; homolog of human YIPF3 [Source:SGD;Acc:S000005207]" Bcin09g05050 1127 yes Bcrid2, DNA methyltranferase Bcin09g05060 233 Effector(V2)|Effector(V1) "Bcpth2, similar to yeast PTH2, One of two mitochondrially-localized peptidyl-tRNA hydrolases; negatively regulates the ubiquitin-proteasome pathway via interactions with ubiquitin-like ubiquitin-associated proteins; dispensable for cell growth; see also PTH1 [Source:SGD;Acc:S000000153]" Bcin09g05070 311 Bcin09g05080 640 Transporter Tetracycline resistance protein, TetA/multidrug resistance protein MdtG + Major facilitator superfamily + Major facilitator superfamily domain Bcin09g05090 459 SignalP-noTM DOMON domain + Cytochrome b561/ferric reductase transmembrane + Cellobiose dehydrogenase, cytochrome domain Bcin09g05100 993 Bcin09g05110 323 Ceramidase Bcin09g05120 214 Cytochrome b5-like heme/steroid binding domain + Cytochrome b5, heme-binding site Bcin09g05130 292 Effector(V1) Bcin09g05140 712 Heterokaryon incompatibility Bcin09g05150 402 Sugar isomerase (SIS) Bcin09g05160 71 Effector(V1) Bcin09g05170 417 Protease//SignalP-noTM Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin09g05180 508 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin09g05190 153 Effector(V2)|Effector(V1) Acyl-ACP thioesterase + HotDog domain Bcin09g05200 457 RNA-binding S4 domain + Pseudouridine synthase, RsuA/RluB/C/D/E/F + Pseudouridine synthase, RluC/RluD, conserved site + Pseudouridine synthase, RluC/RluD + Pseudouridine synthase, catalytic domain Bcin09g05210 501 Signaling pathway Bip1, Transcription factor_bzip Bcin09g05220 1007 SNF2-related + Helicase, C-terminal + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase + Helicase-associated putative binding domain Bcin09g05230 354 Bcin09g05240 557 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin09g05250 357 SignalP-noTM//Early secretome Ubiquitin 3 binding protein But2, C-terminal Bcin09g05260 266 "Bcatg5, similar to yeast ATG5, Conserved protein involved in autophagy and the Cvt pathway; undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation; also involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner [Source:SGD;Acc:S000006070]" Bcin09g05270 529 Bcin09g05280 362 HotDog domain Bcin09g05290 370 Yippee/Mis18 Bcin09g05300 271 Ornithine decarboxylase antizyme + Acyl-CoA N-acyltransferase Bcin09g05310 891 Zinc finger, ZZ-type + Next to BRCA1, central domain Bcin09g05320 399 Bcin09g05330 485 Transporter//SM cluster BIK Bcbik6, Putative MFS-type transporter, in bikaverin biosynthesis gene cluster Bcin09g05340 750 Fungal trans transcription factor//SM cluster BIK Bcbik5, Zn2/Cys6 transcription factor, in bikaverin biosynthesis gene cluster Bcin09g05350 326 SM cluster BIK Bcbik4, Putative NmrA-like protein, in bikaverin biosynthesis gene cluster Bcin09g05360 333 SM cluster BIK//Effector(V2)|Effector(V1) Bcbik3, Putative O-methyltransferase, in bikaverin biosynthesis gene cluster Bcin09g05370 138 SM cluster BIK//Effector(V1) Bcbik2, Putative FAD-dependent monooxygenase, strain 1750, in bikaverin biosynthesis gene cluster Bcin09g05380 631 "Bcmpe1, similar to yeast MPE1, Essential conserved subunit of CPF cleavage and polyadenylation factor; plays a role in 3' end formation of mRNA via the specific cleavage and polyadenylation of pre-mRNA, contains a putative RNA-binding zinc knuckle motif; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000001542]" Bcin09g05390 80 Bcin09g05400 483 Bcdao8, D-amino acid oxidase 8 Bcin09g05410 246 Bcin09g05420 413 Bcin09g05430 1429 Helicase, C-terminal + DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site + Helicase-associated domain + DEAD/DEAH box helicase domain + Domain of unknown function DUF1605 + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin09g05440 489 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid + HAD-like domain Bcin09g05450 148 Effector(V2)|Effector(V1) Bcin09g05460 829 yes CAZy : GH3PCW/FCW Bcsap1, Saponinase Bcin09g05470 605 SignalP-noTM Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin09g05480 116 Effector(V2)|Effector(V1) Carbohydrate-binding WSC Bcin09g05490 349 S-adenosyl-L-methionine-dependent methyltransferase Bcin09g05500 197 Effector(V2)|Effector(V1) NTF2-like domain Bcin09g05510 1180 Transporter "Bcpca1, similar to yeast PCA1, Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; stabilized by Cd binding, which prevents ubiquitination; S288C and other lab strains contain a G970R mutation which eliminates Cd transport function [Source:SGD;Acc:S000000499]" Bcin09g05520 320 P-loop containing nucleoside triphosphate hydrolase Bcin09g05530 368 Tartrate dehydrogenase + Isocitrate/isopropylmalate dehydrogenase, conserved site + Isopropylmalate dehydrogenase-like domain Bcin09g05540 687 Fungal trans transcription factor Transcription factor domain, fungi Bcin09g05550 240 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin09g05560 371 Glyceraldehyde-3-phosphate dehydrogenase, type I + NAD(P)-binding domain + Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain + Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain + Glyceraldehyde 3-phosphate dehydrogenase, active site + Glyceraldehyde/Erythrose phosphate dehydrogenase family Bcin09g05570 522 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin09g05580 609 Bcin09g05590 221 "Bcrpl10, similar to yeast RPL10, Ribosomal 60S subunit protein L10; responsible for joining the 40S and 60S subunits; regulates translation initiation; similar to members of the QM gene family; homologous to mammalian ribosomal protein L10 and bacterial L16; protein abundance increases in response to DNA replication stress; mutations in the human ortholog are associated with development of T-cell acute lymphoblastic leukemia and similar changes in the yeast gene result in ribosome biogenesis defects [Source:SGD;Acc:S000004065]" Bcin09g05600 111 Effector(V2)|Effector(V1) "Bcrpl30, similar to yeast RPL30, Ribosomal 60S subunit protein L30; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript; homologous to mammalian ribosomal protein L30, no bacterial homolog [Source:SGD;Acc:S000002998]" Bcin09g05610 639 Bcin09g05620 198 Effector(V2)|Effector(V1) Bcin09g05630 646 Protease "Bclap2, similar to yeast LAP2, Leucyl aminopeptidase yscIV with epoxide hydrolase activity; metalloenzyme containing one zinc atom; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; also known as leukotriene A4 hydrolase [Source:SGD;Acc:S000004990]" Bcin09g05640 702 Up-regulated during septation protein 1 Bcin09g05650 249 Effector(V2)|Effector(V1) NAD(P)-binding domain Bcin09g05660 842 DNA helicase, UvrD/REP type + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin09g05670 257 Dienelactone hydrolase + Alpha/Beta hydrolase fold Bcin09g05680 483 Bcin09g05690 423 Bcin09g05700 499 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin09g05710 407 Major facilitator superfamily + Major facilitator superfamily domain Bcin09g05720 176 Effector(V1) Bcin09g05730 524 Bcin09g05740 540 SignalP-noTM Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin09g05750 377 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain Bcin09g05760 460 Bcef1a, Translation elongation factor-1 alpha Bcin09g05770 207 Effector(V2)|Effector(V1) Bcin09g05780 145 Effector(V2)|Effector(V1) Bcin09g05790 479 F-box domain Bcin09g05800 295 Effector(V2) "Bcbna6, similar to yeast BNA6, Quinolinate phosphoribosyl transferase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p [Source:SGD;Acc:S000001943]" Bcin09g05810 295 Outer membrane protein/outer membrane enzyme PagP, beta-barrel + Uncharacterised protein family UPF0311 Bcin09g05820 375 "Bcatp12, similar to yeast ATP12, Assembly factor for the F1 sector of mitochondrial F1F0 ATP synthase; conserved protein; required for the assembly of alpha and beta subunits into the F1 sector of the mitochondrial F1F0 ATP synthase; mutation of human ATP12 reduces active ATP synthase levels and is associated with the disorder ATPAF2 deficiency [Source:SGD;Acc:S000003716]" Bcin09g05830 280 Bcin09g05840 1261 Oxysterol-binding protein + Pleckstrin homology domain + Ankyrin repeat + Pleckstrin homology-like domain + Oxysterol-binding protein, conserved site + Ankyrin repeat-containing domain Bcin09g05850 254 Effector(V2) Bcin09g05860 157 Effector(V2) Bcin09g05870 179 Effector(V1) Bcin09g05880 207 Effector(V1) Bcin09g05890 243 Effector(V2)|Effector(V1) Bcin09g05900 179 Effector(V2)|Effector(V1) Bcin09g05910 175 Effector(V2) Bcin09g05920 329 Bcgst10, Glutathione S-transferase Bcin09g05930 1592 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin09g05940 618 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin09g05950 531 CAZy : GT32 Glycosyltransferase, DXD sugar-binding motif + Nucleotide-diphospho-sugar transferases Bcin09g05960 529 Acyltransferase 3 Bcin09g05970 446 Bcin09g05980 165 Effector(V2)|Effector(V1) Bcin09g05990 90 Bcin09g06000 528 SignalP-noTM Bcin09g06010 618 Bcin09g06020 169 SignalP-noTM//Effector(V2)|Effector(V1) Bcin09g06030 579 Transporter Tetracycline resistance protein, TetA/multidrug resistance protein MdtG + Major facilitator superfamily + Major facilitator superfamily domain Bcin09g06040 401 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin09g06050 242 GNAT domain + Acyl-CoA N-acyltransferase Bcin09g06060 315 SignalP-noTM Actin cortical patch SUR7/pH-response regulator PalI Bcin09g06070 323 Bcin09g06080 411 CAZy : GT2 Nucleotide-diphospho-sugar transferases Bcin09g06090 193 Ctr copper transporter Bcin09g06100 211 SignalP-noTM Bcin09g06110 542 Malate synthase + Malate synthase A + Malate synthase G + Malate synthase-like + Malate synthase, conserved site Bcin09g06120 384 "Bczrt1, similar to yeast ZRT1, High-affinity zinc transporter of the plasma membrane; responsible for the majority of zinc uptake; transcription is induced under low-zinc conditions by the Zap1p transcription factor [Source:SGD;Acc:S000003224]" Bcin09g06130 225 yes Effector(V1)//Signaling pathway Bcpls1, Tetraspanin Bcin09g06140 227 MADS box transcription factor//Effector(V1) "Bcmcm1, similar to yeast MCM1, Transcription factor; involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000004646]" Bcin09g06150 538 Magnesium transporter NIPA Bcin09g06160 228 "Bcvma4, similar to yeast VMA4, Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase); V-ATPase is an electrogenic proton pump found throughout the endomembrane system; V1 domain has eight subunits; required for the V1 domain to assemble onto the vacuolar membrane; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005859]" Bcin09g06170 648 Bcin09g06180 1483 Transporter P-type ATPase + P-type ATPase, subfamily IV + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, cytoplasmic domain N + Phospholipid-transporting P-type ATPase + P-type ATPase, C-terminal + P-type ATPase, N-terminal Bcin09g06190 2019 Armadillo-type fold + Helicase Sen1, N-terminal + Probable helicase senataxin + P-loop containing nucleoside triphosphate hydrolase Bcin09g06200 803 Bcin09g06210 66 Effector(V1) Bcin09g06220 929 "Bcrad1, similar to yeast RAD1, Single-stranded DNA endonuclease (with Rad10p); cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein [Source:SGD;Acc:S000005943]" Bcin09g06230 84 Effector(V1) Bcpio11, Gene with a peak of expression during the Outset of colonization Bcin09g06240 656 "Bclas17, similar to yeast LAS17, Actin assembly factor; C-terminal WCA domain activates Arp2/3 complex-mediated nucleation of branched actin filaments and a polyproline domain which can nucleate actin filaments independent of Arp2/3; mutants are defective in actin cytoskeleton dependent processes such as: endocytosis, bud site selection and cytokinesis; localizes with the Arp2/3 complex to actin cortical patches; homolog of the Wiskott-Aldrich Syndrome protein (WASP), implicated in severe immunodeficiency [Source:SGD;Acc:S000005707]" Bcin09g06250 160 "Bctif11, similar to yeast TIF11, Translation initiation factor eIF1A; essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3 [Source:SGD;Acc:S000004873]" Bcin09g06260 245 Bcin09g06270 398 "Bcchs5, similar to yeast CHS5, Component of the exomer complex; exomer also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane; Chs5p is the only protein with a BRCT domain that is not localized to the nucleus [Source:SGD;Acc:S000004322]" Bcin09g06280 263 NAD(P)-binding domain Bcin09g06290 728 Rad21/Rec8-like protein, N-terminal + Rad21/Rec8-like protein, C-terminal Bcin09g06300 896 SignalP-noTM TRP-like family + ML-like domain Bcin09g06310 103 Bcin09g06320 225 Bcin09g06330 482 Bcin09g06340 263 Isopenicillin N synthase-like Bcin09g06350 104 Polyketide synthase, dehydratase domain Bcin09g06360 286 Acyl carrier protein-like + Polyketide synthase, ketoreductase domain + NAD(P)-binding domain Bcin09g06370 1090 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin09g06380 343 "Bctyw3, similar to yeast TYW3, tRNA methyltransferase required for synthesis of wybutosine; a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions [Source:SGD;Acc:S000003018]" Bcin09g06390 172 Protein of unknown function DUF1690 Bcin09g06400 613 BcfreB, Similar to yeast ferric reductase Fre1 Bcin09g06410 639 Pyruvate carboxyltransferase + Alpha-isopropylmalate/homocitrate synthase, conserved site + 2-isopropylmalate synthase + 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain + Aldolase-type TIM barrel Bcin09g06420 871 "Bckap95, similar to yeast KAP95, Karyopherin beta; forms a complex with Srp1p/Kap60p; interacts with nucleoporins to mediate nuclear import of NLS-containing cargo proteins via the nuclear pore complex; regulates PC biosynthesis; GDP-to-GTP exchange factor for Gsp1p [Source:SGD;Acc:S000004339]" Bcin09g06430 334 Bcin09g06440 756 Bcin09g06450 159 Nascent polypeptide-associated complex NAC domain Bcin09g06460 206 Effector(V1) Bcin09g06470 488 "Bctrm44, similar to yeast TRM44, tRNA(Ser) Um(44) 2'-O-methyltransferase; involved in maintaining levels of the tRNA-Ser species tS(CGA) and tS(UGA); conserved among metazoans and fungi but there does not appear to be a homolog in plants; TRM44 is a non-essential gene [Source:SGD;Acc:S000005951]" Bcin09g06480 155 Ribosomal protein L24e-related + Ribosomal protein L24e, conserved site Bcin09g06490 464 P-loop containing nucleoside triphosphate hydrolase Bcin09g06500 542 "Bcalo1, similar to yeast ALO1, D-Arabinono-1,4-lactone oxidase; catalyzes the final step in biosynthesis of dehydro-D-arabinono-1,4-lactone, which is protective against oxidative stress [Source:SGD;Acc:S000004551]" Bcin09g06510 493 Domain of unknown function DUF336 Bcin09g06520 257 "Bcshb17, similar to yeast SHB17, Sedoheptulose bisphosphatase involved in riboneogenesis; dephosphorylates sedoheptulose 1,7-bisphosphate, which is converted via the nonoxidative pentose phosphate pathway to ribose-5-phosphate; facilitates the conversion of glycolytic intermediates to pentose phosphate units; also has fructose 1,6-bisphosphatase activity but this is probably not biologically relevant, since deletion does not affect FBP levels; GFP-fusion protein localizes to the cytoplasm and nucleus [Source:SGD;Acc:S000001751]" Bcin09g06530 145 Effector(V1) Bcin09g06540 344 Xylose isomerase-like, TIM barrel domain Bcin09g06550 493 Zinc finger, RING-type + Zinc finger, C6HC-type + E3 ubiquitin ligase RBR family + Zinc finger, RING/FYVE/PHD-type Bcin09g06560 532 SignalP-noTM Bcin09g06570 154 Effector(V2)|Effector(V1) Dehydroquinase, class II + Dehydroquinase, class II, conserved site Bcin09g06580 984 P-loop containing nucleoside triphosphate hydrolase Bcin09g06590 812 SNF2-related + Helicase, C-terminal + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin09g06600 473 EEIG1/EHBP1 N-terminal domain Bcin09g06610 173 Effector(V2)|Effector(V1) Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + Cyclophilin-type peptidyl-prolyl cis-trans isomerase + Cyclophilin-like domain Bcin09g06620 655 Protease Presenilin/signal peptide peptidase + Peptidase A22B, signal peptide peptidase Bcin09g06630 389 GNAT domain + Acyl-CoA N-acyltransferase Bcin09g06640 476 Bcin09g06650 464 Bcin09g06660 519 Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin09g06670 381 Bcin09g06680 528 Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin09g06690 578 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin09g06700 102 Effector(V2)|Effector(V1) Bcin09g06710 594 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin09g06720 189 Bcin09g06730 376 CAZy : AA9 //SignalP-noTM Glycoside hydrolase, family 61 Bcin09g06740 300 Bcin09g06750 325 CAZy : AA9 //SignalP-TM Glycoside hydrolase, family 61 Bcin09g06760 293 Helicase, C-terminal + P-loop containing nucleoside triphosphate hydrolase Bcin09g06770 226 Effector(V2)|Effector(V1) Bcin09g06780 160 Bcin09g06790 318 Bcin09g06800 1042 Bcin09g06810 66 SignalP-noTM//Effector(V2)|Effector(V1) Bcin09g06820 499 UBX domain + UAS + UBA-like + Thioredoxin-like fold + Ubiquitin-related domain Bcin09g06830 690 "Bcpan3, similar to yeast PAN3, Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex; poly (A) mRNA binding subunit which recruits mRNA to the complex; the Pan2p-Pan3p complex controls poly(A) tail length and regulates the stoichiometry and activity of postreplication repair complexes [Source:SGD;Acc:S000001508]" Bcin09g06840 686 Protein of unknown function DUF4246 Bcin09g06850 671 Heterokaryon incompatibility Bcin09g06860 853 Heterokaryon incompatibility Bcin09g06870 798 Choline kinase, N-terminal + Protein kinase-like domain Bcin09g06880 574 yes Protease//SignalP-noTM Bclip1, Similar to lipase Bcin09g06890 408 Wax synthase domain Bcin09g06900 641 yes Signaling pathway Bos5, Mitogen-activated protein kinase (MAPK): MAPKK Bcin09g06910 555 Auxin efflux carrier Bcin09g06920 84 SignalP-noTM//Effector(V1) Bcin09g06930 457 Bcin09g06940 84 Effector(V2) Splicing factor 3B subunit 5/RDS3 complex subunit 10 + Splicing factor 3B, subunit 5 Bcin09g06950 340 MAGE homology domain Bcin09g06960 954 Protein Sls1 Bcin09g06970 281 "Bcrib7, similar to yeast RIB7, Diaminohydroxyphoshoribosylaminopyrimidine deaminase; catalyzes the second step of the riboflavin biosynthesis pathway [Source:SGD;Acc:S000000357]" Bcin09g06980 343 NmrA-like domain + NAD(P)-binding domain Bcin09g06990 808 CAZy : GH3PCW/FCW //Early secretome Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Glycoside hydrolase, family 3, active site + Fibronectin type III-like domain Bcin09g07000 456 yes BcTol1, Tom-1 like protein Bcin09g07010 579 Protease//SignalP-noTM Gamma-glutamyltranspeptidase + Nucleophile aminohydrolases, N-terminal Bcin09g07020 524 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin09g07030 179 Effector(V2)|Effector(V1) GNAT domain + Acyl-CoA N-acyltransferase Bcin09g07040 314 Bcin09g07050 140 Effector(V1) "Bclsm7, similar to yeast LSM7, Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; protein abundance increases and forms cytoplasmic foci in response to DNA replication stress [Source:SGD;Acc:S000005091]" Bcin09g07060 1182 Fungal lipase-like domain + Alpha/Beta hydrolase fold Bcin09g07070 426 Protease Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin09g07080 214 Bcin09g07090 671 Beta-lactamase-like + SCP2 sterol-binding domain + Alkyl sulfatase dimerisation domain + Alkyl sulfatase, C-terminal Bcin09g07100 90 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin09g07110 384 Glycoside hydrolase, family 43 + Glycosyl hydrolase, five-bladed beta-propellor domain Bcin09g07120 444 Bcin09g07130 380 Bcin09g07140 395 Bcin10g00010 348 SM 0 Bcin10g00020 572 SM cluster PKS7 Major facilitator superfamily + Major facilitator superfamily domain Bcin10g00030 143 SM cluster PKS7 EthD domain + Dimeric alpha-beta barrel Bcin10g00040 4053 SM cluster PKS7 (KE) Bcpks7, Polyketide synthase (PKS-NRPS) Bcin10g00050 122 SM 0//Effector(V1) Bcin10g00060 304 SM cluster PKS7 "Bcmcr1, similar to yeast MCR1, Mitochondrial NADH-cytochrome b5 reductase; involved in ergosterol biosynthesis [Source:SGD;Acc:S000001633]" Bcin10g00070 644 Bcin10g00080 530 Bcin10g00090 61 Effector(V2)|Effector(V1) Bcin10g00100 283 Bcin10g00110 261 Effector(V1) 6-phosphogluconolactonase, DevB-type + Glucosamine/galactosamine-6-phosphate isomerase Bcin10g00120 303 "Bcpho13, similar to yeast PHO13, Alkaline phosphatase specific for p-nitrophenyl phosphate; also has protein phosphatase activity [Source:SGD;Acc:S000002395]" Bcin10g00130 662 SET domain + Zinc finger, MYND-type + Tetratricopeptide-like helical domain Bcin10g00140 265 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin10g00150 288 Protease Amidohydrolase 1 + Metal-dependent hydrolase, composite domain + Metal-dependent hydrolase Bcin10g00160 813 Bcin10g00170 910 Bcin10g00180 439 Bcin10g00190 452 Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin10g00200 527 Bcin10g00210 319 Bcin10g00220 122 Bcin10g00230 324 Flavin reductase-like, FMN-binding + FMN-binding split barrel Bcin10g00240 173 Effector(V1) Ribosomal protein L31 Bcin10g00250 586 "Bcvps5, similar to yeast VPS5, Nexin-1 homolog; required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to late Golgi; structural component of retromer membrane coat complex; forms a retromer subcomplex with Vps17p; required for recruiting the retromer complex to the endosome membranes; VPS5 has a paralog, YKR078W, that arose from the whole genome duplication [Source:SGD;Acc:S000005595]" Bcin10g00260 192 Effector(V1) Mediator complex, subunit Med11 Bcin10g00270 722 "Bctaf5, similar to yeast TAF5, Subunit (90 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification [Source:SGD;Acc:S000000402]" Bcin10g00280 407 Bcin10g00290 387 SignalP-noTM Bcin10g00300 701 Heat shock protein Hsp90 family + Histidine kinase-like ATPase, C-terminal domain + Heat shock protein Hsp90, conserved site + Ribosomal protein S5 domain 2-type fold + Heat shock protein Hsp90, N-terminal Bcin10g00310 887 CAZy : GH55FCW //SignalP-noTM//Early secretome Pectin lyase fold/virulence factor + Pectin lyase fold + Endosialidase, N-terminal extension domain + Pectate lyase superfamily protein Bcin10g00320 267 Bcin10g00330 797 Potassium transporter Bcin10g00340 537 "Bcear1, similar to yeast EAR1, Specificity factor required for Rsp5p-dependent ubiquitination; also required for sorting of specific cargo proteins at the multivesicular body; mRNA is targeted to the bud via the mRNA transport system involving She2p [Source:SGD;Acc:S000004781]" Bcin10g00350 369 Bcin10g00360 243 Bcin10g00370 307 Fat storage-inducing transmembrane protein Bcin10g00380 346 SignalP-noTM Bcin10g00390 241 Small GTPase superfamily + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin10g00400 657 "Bckri1, similar to yeast KRI1, Essential nucleolar protein required for 40S ribosome biogenesis; associate with snR30; physically and functionally interacts with Krr1p [Source:SGD;Acc:S000005252]" Bcin10g00410 1415 Pleckstrin homology domain + Pleckstrin homology-like domain + Domain of unknown function DUF4782 Bcin10g00420 780 START-like domain Bcin10g00430 363 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin10g00440 297 Flavin reductase-like, FMN-binding + FMN-binding split barrel Bcin10g00450 467 yes Signaling pathway Bcpde1, CAMP phosphodiesterase Bcin10g00460 1873 AMP-dependent synthetase/ligase + DMAP1-binding Bcin10g00470 642 Bcin10g00480 321 SignalP-noTM Bcin10g00490 913 Alpha/Beta hydrolase fold Bcin10g00500 165 Effector(V2)|Effector(V1) Zinc-binding domain Bcin10g00510 847 "Bchrd1, similar to yeast HRD1, Ubiquitin-protein ligase; functions in ER retention of misfolded proteins; required for ER-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger; likely plays a general role in targeting proteins that persistently associate with and potentially obstruct the ER-localized translocon [Source:SGD;Acc:S000005373]" Bcin10g00520 612 Cys2His2 transcription factor Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like + Transcription factor Ovo-like 2 + C2H2- zinc finger protein family Bcin10g00530 1995 Zinc finger, CCCH-type + Zinc finger, NF-X1-type + P-loop containing nucleoside triphosphate hydrolase Bcin10g00540 271 "Bcpib2, similar to yeast PIB2, Protein of unknown function; contains FYVE domain; similar to Fab1 and Vps27 [Source:SGD;Acc:S000002991]" Bcin10g00550 223 Effector(V1) "Bcarl3, similar to yeast ARL3, ARF-like small GTPase of the RAS superfamily; required for recruitment of Arl1p, a GTPase that regulates membrane traffic, to the Golgi apparatus; NatC-catalyzed N-terminal acetylation regulates Golgi membrane association mediated by interaction with membrane receptor, Sys1p; similar to ADP-ribosylation factor and orthologous to mammalian ARFRP1 [Source:SGD;Acc:S000005972]" Bcin10g00560 504 Bcin10g00570 757 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin10g00580 2080 SNF2-related + Helicase, C-terminal + Sterile alpha motif/pointed domain + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin10g00590 509 "Bcgsh2, similar to yeast GSH2, Glutathione synthetase; catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock [Source:SGD;Acc:S000005409]" Bcin10g00600 135 Effector(V2)|Effector(V1) Primosome PriB/single-strand DNA-binding + Single-stranded DNA-binding protein + Nucleic acid-binding, OB-fold Bcin10g00610 1164 SignalP-noTM Domain of unknown function DUF4203 Bcin10g00620 265 Golgin subfamily A member 7/ERF4 Bcin10g00630 406 "Bcfyv10, similar to yeast FYV10, Subunit of GID complex; involved in proteasome-dependent catabolite inactivation of gluconeogenic enzymes FBPase, PEPCK, and c-MDH; forms dimer with Rmd5p that is then recruited to GID Complex by Gid8p; contains a degenerate RING finger motif needed for GID complex ubiquitin ligase activity in vivo, as well as CTLH and CRA domains; plays role in anti-apoptosis; required for survival upon exposure to K1 killer toxin [Source:SGD;Acc:S000001359]" Bcin10g00640 295 Helix-loop-helix (HLH) transcription factor "Bccbf1, similar to yeast CBF1, Basic helix-loop-helix (bHLH) protein; forms homodimer to bind E-box consensus sequence CACGTG present at MET gene promoters and centromere DNA element I (CDEI); affects nucleosome positioning at this motif; associates with other transcription factors such as Met4p and Isw1p to mediate transcriptional activation or repression; associates with kinetochore proteins, required for chromosome segregation; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003821]" Bcin10g00650 1541 Transporter "Bcycf1, similar to yeast YCF1, Vacuolar glutathione S-conjugate transporter; ABC-C transporter of the ATP-binding cassette family; required for vacuole fusion; forms stable complexes with vacuole fusion machinery; regulates Vam7p recruitment to vacuoles; role in detoxifying metals (Cd, Hg, As); transports GSSG that is not immediately reduced in cytosol to vacuole; transports unconjugated bilirubin, selenodigluthatione, oxidized glutathione; similar to human cystic fibrosis protein CFTR [Source:SGD;Acc:S000002542]" Bcin10g00660 637 Protein of unknown function DUF2841 Bcin10g00670 652 SignalP-TM Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin10g00680 492 Bcin10g00690 301 Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin10g00700 677 "Bcste3, similar to yeast STE3, Receptor for a factor pheromone; couples to MAP kinase cascade to mediate pheromone response; transcribed in alpha cells and required for mating by alpha cells, ligand bound receptors endocytosed and recycled to the plasma membrane; GPCR [Source:SGD;Acc:S000001661]" Bcin10g00710 98 Effector(V1) Bcin10g00720 370 Protease Peptidase C45 Bcin10g00730 204 Effector(V1) Bcin10g00740 254 yes Effector(V2) Bcgst1, Glutathione-S-transferase Bcin10g00750 600 "Bcmsl5, similar to yeast MSL5, Component of commitment complex; which defines first step in splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000004106]" Bcin10g00760 1484 Bcin10g00770 330 CAZy : GT8 Nucleotide-diphospho-sugar transferases + Glucose N-acetyltransferase 1 Bcin10g00780 1885 SNF2-related + Helicase, C-terminal + Armadillo-like helical + Helicase superfamily 1/2, ATP-binding domain + Armadillo-type fold + Domain of unknown function DUF3535 + P-loop containing nucleoside triphosphate hydrolase Bcin10g00790 1017 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain Bcin10g00800 186 Effector(V1) Bcin10g00810 314 Bcin10g00820 301 Bcin10g00830 551 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin10g00840 538 Major facilitator superfamily + Major facilitator superfamily domain Bcin10g00850 505 SignalP-noTM FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin10g00860 445 Pleckstrin homology domain + Pleckstrin homology-like domain Bcin10g00870 148 Effector(V1) Nnf1 Bcin10g00880 489 Axin interactor, dorsalization-associated protein, N-terminal Bcin10g00890 573 FAD-linked oxidase, C-terminal + FAD linked oxidase, N-terminal + FAD-linked oxidase-like, C-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 + Vanillyl-alcohol oxidase, C-terminal subdomain 2 Bcin10g00900 555 Coenzyme A transferase family I + 3-oxoacid CoA-transferase, subunit B + 3-oxoacid CoA-transferase Bcin10g00910 256 O-methyltransferase, family 2 + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin10g00920 347 "Bcbmt5, similar to yeast BMT5, Methyltransferase required for m3U2634 methylation of the 25S rRNA; S-adenosylmethionine-dependent; associates with precursors of the 60S ribosomal subunit; predicted to be involved in ribosome biogenesis [Source:SGD;Acc:S000001358]" Bcin10g00930 401 "Bcaos1, similar to yeast AOS1, Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006384]" Bcin10g00940 576 Bcin10g00950 577 CoA-transferase family III + CoA-transferase family III domain Bcin10g00960 836 SignalP-noTM Carbohydrate-binding WSC Bcin10g00970 224 GNAT domain + Acyl-CoA N-acyltransferase Bcin10g00980 504 Bcin10g00990 195 Effector(V2) "Bcnat3, similar to yeast NAT3, Catalytic subunit of the NatB N-terminal acetyltransferase; NatB catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met [Source:SGD;Acc:S000006335]" Bcin10g01000 397 Bcin10g01010 352 Bcin10g01020 147 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Bcin10g01030 156 Effector(V2)|Effector(V1) Bcprx9, Peroxiredoxin (Redoxin) Bcin10g01040 718 AAA+ ATPase domain + DNA helicase + Ribosomal protein L9/RNase H1, N-terminal + DNA helicase Pif1 like + Ribonuclease H1, N-terminal + P-loop containing nucleoside triphosphate hydrolase Bcin10g01050 315 Effector(V1) RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin10g01060 821 Domain of unknown function DUF1793 + Domain of unknown function DUF4965 + Domain of unknown function DUF5127 Bcin10g01070 247 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin10g01080 642 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin10g01090 325 HIT-like domain + ATP adenylyltransferase, C-terminal Bcin10g01100 540 Myb-like domain Bcin10g01110 739 Bcin10g01120 104 Effector(V2)|Effector(V1) Bcin10g01130 990 Sec39 domain Bcin10g01140 107 Effector(V2)|Effector(V1) Bcin10g01150 180 Effector(V2) S-adenosyl-L-methionine-dependent methyltransferase Bcin10g01160 281 Bcin10g01170 339 Ketopantoate reductase ApbA/PanE + 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + Ketopantoate reductase, N-terminal domain + Ketopantoate reductase, C-terminal domain + NAD(P)-binding domain Bcin10g01180 629 "Bcarb1, similar to yeast ARB1, ATPase of the ATP-binding cassette (ABC) family; involved in 40S and 60S ribosome biogenesis, has similarity to Gcn20p; shuttles from nucleus to cytoplasm, physically interacts with Tif6p, Lsg1p [Source:SGD;Acc:S000000838]" Bcin10g01190 1744 "Bcino80, similar to yeast INO80, ATPase and nucleosome spacing factor; subunit of complex containing actin and actin-related proteins that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; promotes nucleosome shifts in the 3 prime direction; has a role in modulating stress gene transcription [Source:SGD;Acc:S000003118]" Bcin10g01200 592 Bcin10g01210 71 Effector(V2)|Effector(V1) Glucose-repressible protein Grg1 Bcin10g01220 619 "Bcgrr1, similar to yeast GRR1, F-box protein component of an SCF ubiquitin-ligase complex; modular substrate specificity factor which associates with core SCF (Cdc53p, Skp1p and Hrt1p/Rbx1p) to form the SCF(Grr1) complex; SCF(Grr1) acts as a ubiquitin-protein ligase directing ubiquitination of substrates such as: Gic2p, Mks1p, Mth1p, Cln1p, Cln2p and Cln3p; involved in carbon catabolite repression, glucose-dependent divalent cation transport, glucose transport, morphogenesis, and sulfite detoxification [Source:SGD;Acc:S000003850]" Bcin10g01230 374 Chalcone isomerase Bcin10g01240 105 Effector(V2)|Effector(V1) Bcgrx1, Glutaredoxin Bcin10g01250 298 yes BcBAG1, Bcl-2 associated athanogene Bcin10g01260 202 Ribosomal protein L13, eukaryotic/archaeal + Ribosomal protein L13 + Ribosomal protein L13, conserved site Bcin10g01270 582 AMP-dependent synthetase/ligase + AMP-binding enzyme C-terminal domain Bcin10g01280 766 Bcin10g01290 296 SignalP-noTM Bcin10g01300 290 S-adenosyl-L-methionine-dependent methyltransferase Bcin10g01310 501 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin10g01320 328 "Bcpho85, similar to yeast PHO85, Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle [Source:SGD;Acc:S000005952]" Bcin10g01330 719 Septin + Sigma-54 interaction domain, ATP-binding site 1 + P-loop containing nucleoside triphosphate hydrolase + Septin-type guanine nucleotide-binding (G) domain Bcin10g01340 423 SignalP-noTM Bcin10g01350 300 yes Bcstr2, Short-chain dehydrogenase Bcin10g01360 270 Bcin10g01370 1683 Zinc finger, RanBP2-type + Zinc finger, CCHC-type Bcin10g01380 532 RNA recognition motif domain + Nuclear transport factor 2 + Nucleotide-binding alpha-beta plait domain + Nuclear transport factor 2, eukaryote + NTF2-like domain Bcin10g01390 488 Tetratricopeptide-like helical domain Bcin10g01400 128 Bcin10g01410 555 "Bcpob3, similar to yeast POB3, Subunit of the heterodimeric FACT complex (Spt16p-Pob3p); FACT associates with chromatin via interaction with Nhp6Ap and Nhp6Bp, and reorganizes nucleosomes to facilitate access to DNA by RNA and DNA polymerases; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004534]" Bcin10g01430 343 Bcin10g01440 840 Cytochrome b561/ferric reductase transmembrane Bcin10g01450 571 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin10g01460 505 Bcin10g01470 338 Effector(V2) GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin10g01480 329 S-adenosyl-L-methionine-dependent methyltransferase Bcin10g01490 527 Major facilitator superfamily + Major facilitator superfamily domain Bcin10g01500 149 ATPase, F0 complex, subunit C + V-ATPase proteolipid subunit C-like domain + ATPase, F0 complex, subunit C, DCCD-binding site Bcin10g01510 372 SignalP-noTM Bcin10g01520 581 "Bcelp3, similar to yeast ELP3, Subunit of Elongator complex; Elongator is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin [Source:SGD;Acc:S000006007]" Bcin10g01530 329 Effector(V2) CoA-binding + Succinyl-CoA ligase, alpha subunit + ATP-citrate lyase/succinyl-CoA ligase + NAD(P)-binding domain + Succinyl-CoA synthetase-like + ATP-citrate lyase/succinyl-CoA ligase, active site + ATP-citrate lyase/succinyl-CoA ligase, conserved site Bcin10g01540 437 "Bcapm4, similar to yeast APM4, Cargo-binding mu subunit of AP-2; AP-2 is a heterotetrameric endocytic cargo-binding adaptor that facilitates uptake of membrane proteins during clathrin-mediated endocytosis; Apm4p is required for AP-2 function and localization, and binds cell wall stress receptor Mid2p; AP-2 is required for cell polarity responses to pheromone, nutritional status and cell wall damage in S. cerevisiae, and for hyphal growth in C. albicans; AP-2 complex is conserved in mammals [Source:SGD;Acc:S000005423]" Bcin10g01550 645 Proton-dependent oligopeptide transporter family + Major facilitator superfamily domain Bcin10g01560 166 Effector(V2) Bcin10g01570 339 NAD(P)-binding domain + Ergot alkaloid biosynthesis protein Bcin10g01580 503 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin10g01590 569 Major facilitator superfamily domain + Autophagy-related protein 22-like Bcin10g01600 979 Hydantoinase/oxoprolinase + Hydantoinaseoxoprolinase, N-terminal + Protein of unknown function DUF917 + Protein of unknown function DUF917, C-terminal + Protein of unknown function DUF917, N-terminal Bcin10g01610 560 CAZy : GH43PCW hemicellulose or pectin//SignalP-noTM Glycoside hydrolase, family 43 + Glycosyl hydrolase, five-bladed beta-propellor domain Bcin10g01620 520 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin10g01630 282 "Bcayr1, similar to yeast AYR1, Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase; NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase involved in phosphatidic acid biosynthesis; lipid droplet triacylglycerol lipase involved in the mobilization of non-polar lipids; found in lipid particles, the endoplasmic reticulum and the mitochondrial outer membrane; required for spore germination; role in cell wall biosynthesis; capable of metabolizing steroid hormones; oleic acid inducible [Source:SGD;Acc:S000001386]" Bcin10g01640 210 SignalP-noTM CHRD Bcin10g01650 461 Bcin10g01660 423 Glucose receptor Git3, N-terminal Bcin10g01670 497 Bcin10g01680 520 Bcin10g01690 1531 S-adenosyl-L-methionine-dependent methyltransferase Bcin10g01700 264 Effector(V1) SAP domain Bcin10g01710 636 Bcin10g01720 568 Xanthine/uracil/vitamin C permease Bcin10g01730 356 Bcin10g01740 332 Bcin10g01750 703 Heterokaryon incompatibility Bcin10g01760 378 Bcin10g01770 443 Bcin10g01780 251 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Protein of unknown function DUF4237 Bcin10g01790 628 Bcin10g01800 590 Bcin10g01810 703 Bcin10g01820 654 Bcin10g01830 149 Bcin10g01840 330 Protease Alpha/beta hydrolase fold-1 + Epoxide hydrolase-like + Alpha/Beta hydrolase fold Bcin10g01850 593 Bcin10g01860 636 Bcin10g01870 550 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin10g01880 521 Flavin amine oxidase + Amine oxidase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin10g01890 669 Protease//SignalP-noTM Peptidase S8/S53 domain + Proteinase inhibitor, propeptide + Peptidase S53, propeptide + Sedolisin domain Bcin10g01900 246 SignalP-noTM Bcin10g01910 706 Protease Peptidase C2, calpain, catalytic domain + Peptidase C2, calpain family Bcin10g01920 510 Folylpolyglutamate synthetase + Mur ligase, C-terminal + Mur ligase, central Bcin10g01930 233 Effector(V1) Bcin10g01940 626 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin10g01950 656 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin10g01960 853 SignalP-noTM Bcin10g01970 192 Effector(V2)|Effector(V1) Bcin10g01980 475 SignalP-noTM Histidine phosphatase superfamily, clade-2 + Histidine acid phosphatase, eukaryotic + Histidine phosphatase superfamily Bcin10g01990 421 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin10g02000 338 Protein of unknown function DUF2305 + Alpha/Beta hydrolase fold Bcin10g02010 990 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB Bcin10g02020 223 BTB/POZ-like + Potassium channel tetramerisation-type BTB domain + BTB/POZ fold Bcin10g02030 155 Effector(V1) Bcin10g02040 677 SAP domain Bcin10g02050 787 Dynamin central domain + Dynamin, GTPase domain + GTPase effector domain, GED + Dynamin superfamily + P-loop containing nucleoside triphosphate hydrolase + Dynamin-type guanine nucleotide-binding (G) domain Bcin10g02060 360 Oxidoreductase, N-terminal + Oxidoreductase, C-terminal + NAD(P)-binding domain Bcin10g02070 326 Amidohydrolase 1 + Amino-carboxymuconate-semialdehyde decarboxylase + Metal-dependent hydrolase Bcin10g02080 793 Bcin10g02090 380 "Bcccl1, similar to yeast CCL1, Cyclin associated with protein kinase Kin28p; Kin28p is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters [Source:SGD;Acc:S000006229]" Bcin10g02100 543 Taurine catabolism dioxygenase TauD/TfdA + Domain of unknown function DUF971 + Trimethyllysine dioxygenase Bcin10g02110 196 Bcin10g02120 319 Bcin10g02130 805 "Bcarp8, similar to yeast ARP8, Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; has mRNA binding activity [Source:SGD;Acc:S000005667]" Bcin10g02140 1347 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin10g02150 359 Bcin10g02160 169 Effector(V1) Bcin10g02170 58 Effector(V2)|Effector(V1) Bcin10g02180 215 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome BcCFEM1, CFEM (Common in several Fungal Extracellular Membrane protein) domain-containing protein with putative GPI-anchored site Bcin10g02190 121 Effector(V2)|Effector(V1) Bcin10g02200 879 CRIB domain Bcin10g02210 440 Chromo/chromo shadow domain + Chromo domain-like + Chromo domain, conserved site + Chromo domain Bcin10g02220 757 Patatin/Phospholipase A2-related + Acyl transferase/acyl hydrolase/lysophospholipase + Triacylglycerol lipase Bcin10g02230 189 SignalP-noTM//Effector(V1) "Bcsar1, similar to yeast SAR1, GTPase, GTP-binding protein of the ARF family; component of COPII coat of vesicles; required for transport vesicle formation during ER to Golgi protein transport; lowers membrane rigidity helping in vesicle formation [Source:SGD;Acc:S000006139]" Bcin10g02240 340 "Bcprp18, similar to yeast PRP18, Splicing factor and component of snRNP U5; factor involved in the positioning of the 3' splice site during the second catalytic step of splicing; interacts with Slu7p [Source:SGD;Acc:S000003238]" Bcin10g02250 259 Effector(V1) Sin3 associated polypeptide p18 Bcin10g02260 74 Effector(V2)|Effector(V1) Bcin10g02270 259 Bcgst12, Glutathione S-transferase Bcin10g02280 624 CAZy : GT8 Glycosyl transferase, family 8 + Nucleotide-diphospho-sugar transferases Bcin10g02290 515 Protease "Bcape4, similar to yeast APE4, Cytoplasmic aspartyl aminopeptidase with possible vacuole function; Cvt pathway cargo protein; cleaves unblocked N-terminal acidic amino acids from peptide substrates; forms a 12-subunit homo-oligomer; M18 metalloprotease family [Source:SGD;Acc:S000001155]" Bcin10g02300 1530 Coactivator CBP, KIX domain Bcin10g02310 503 Transcription factor Nrm1/Whi5 Bcin10g02320 594 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin10g02330 163 "Bcrpo26, similar to yeast RPO26, RNA polymerase subunit ABC23; common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit [Source:SGD;Acc:S000006391]" Bcin10g02340 286 Protease//Effector(V2) Putative esterase + S-formylglutathione hydrolase + Alpha/Beta hydrolase fold Bcin10g02350 847 "Bcafi1, similar to yeast AFI1, Arf3p polarization-specific docking factor; required for the polarized distribution of the ADP-ribosylation factor, Arf3p; participates in polarity development and maintenance of a normal haploid budding pattern; interacts with Cnm7p [Source:SGD;Acc:S000005655]" Bcin10g02360 302 EF-hand domain + EF-hand domain pair + EF-Hand 1, calcium-binding site Bcin10g02370 505 Bcin10g02380 690 LMBR1-like membrane protein Bcin10g02390 529 Bcin10g02400 282 Nicotinamide N-methyltransferase-like + S-adenosyl-L-methionine-dependent methyltransferase Bcin10g02410 305 "Bcefg1, similar to yeast EFG1, Essential protein required for maturation of 18S rRNA; null mutant is sensitive to hydroxyurea and is delayed in recovering from alpha-factor arrest; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus [Source:SGD;Acc:S000007608]" Bcin10g02420 1062 "Bcsea4, similar to yeast SEA4, Subunit of the SEA (Seh1-associated) complex; SEA is a coatomer-related complex that associates dynamically with the vacuole; has an N-terminal beta-propeller fold and a C-terminal RING motif; promoter contains multiple GCN4 binding sites [Source:SGD;Acc:S000000200]" Bcin10g02430 1023 "Bclos1, similar to yeast LOS1, Nuclear pore protein; involved in nuclear export of pre-tRNA and in re-export of mature tRNAs after their retrograde import from the cytoplasm [Source:SGD;Acc:S000001688]" Bcin10g02440 690 Tetratricopeptide TPR1 + DnaJ domain + Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + DnaJ domain, conserved site + Tetratricopeptide repeat Bcin10g02450 585 "Bcxks1, similar to yeast XKS1, Xylulokinase; converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains [Source:SGD;Acc:S000003426]" Bcin10g02460 393 Cation efflux protein + Cation efflux protein transmembrane domain + Cation efflux protein cytoplasmic domain Bcin10g02470 407 Sirtuin family + Sirtuin family, catalytic core domain + Sirtuin family, catalytic core small domain + DHS-like NAD/FAD-binding domain Bcin10g02480 191 Effector(V2)|Effector(V1) Bcin10g02490 2122 Protease "Bcesp1, similar to yeast ESP1, Separase, a caspase-like cysteine protease; promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibits protein phosphatase 2A-Cdc55p to promote mitotic exit; inhibited by Pds1p; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003330]" Bcin10g02500 245 "Bcisy1, similar to yeast ISY1, Member of the NineTeen Complex (NTC); NTC contains Prp19p and stabilizes U6 snRNA in catalytic forms of spliceosome containing U2, U5, and U6 snRNAs; interacts with Prp16p to modulate splicing fidelity; isy1 syf2 cells have defective spindles [Source:SGD;Acc:S000003811]" Bcin10g02510 584 Tetratricopeptide-like helical domain Bcin10g02520 134 Effector(V2)|Effector(V1) Bcin10g02530 402 yes Protease//SignalP-noTM Bcser1, Subtilisine-like protease Bcin10g02540 777 Bcin10g02550 230 Bcin10g02560 276 SignalP-noTM Bcprd7, Peroxidase Bcin10g02570 459 Bcin10g02580 348 Macrophage migration inhibitory factor + Tautomerase/MIF superfamily Bcin10g02590 354 "Bcgtr2, similar to yeast GTR2, Putative GTP binding protein; negatively regulates Ran/Tc4 GTPase cycle; activates transcription; subunit of EGO and GSE complexes; required for sorting of Gap1p; localizes to cytoplasm and to chromatin; homolog of human RagC and RagD [Source:SGD;Acc:S000003395]" Bcin10g02600 544 Bcin10g02610 496 "Bcpbn1, similar to yeast PBN1, Component of glycosylphosphatidylinositol-mannosyltransferase I; essential component; required for the autocatalytic post-translational processing of the protease B precursor Prb1p; localizes to ER in lumenal orientation; homolog of mammalian PIG-X [Source:SGD;Acc:S000000557]" Bcin10g02620 304 SignalP-noTM Protein of unknown function DUF1183, TMEM66 Bcin10g02630 709 "Bcbre1, similar to yeast BRE1, E3 ubiquitin ligase; forms heterodimer with Rad6p to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control; interacts with RNA-binding protein Npl3p, linking histone ubiquitination to mRNA processing; Bre1p-dependent histone ubiquitination promotes pre-mRNA splicing [Source:SGD;Acc:S000002232]" Bcin10g02640 670 "Bcbdp1, similar to yeast BDP1, Essential subunit of RNA polymerase III transcription factor (TFIIIB); TFIIIB is involved in transcription of genes encoding tRNAs, 5S rRNA, U6 snRNA, and other small RNAs [Source:SGD;Acc:S000004984]" Bcin10g02650 478 CAZy : GH1PCW/FCW Glycoside hydrolase, family 1 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Glycosyl hydrolases family 1, N-terminal conserved site Bcin10g02660 233 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin10g02670 131 Effector(V1) Bcin10g02680 572 Bcin10g02690 51 Effector(V1) Bcin10g02700 876 Bcin10g02710 730 Bcin10g02720 176 Protease Beta-lactamase-related + Beta-lactamase/transpeptidase-like Bcin10g02730 412 Bcin10g02740 323 Bcin10g02750 238 Bcin10g02760 279 Bcin10g02770 529 Bcin10g02780 437 Bcin10g02790 584 Bcin10g02800 408 Bcin10g02810 1696 "Bcyta7, similar to yeast YTA7, Protein that localizes to chromatin; has a role in regulation of histone gene expression; has a bromodomain-like region that interacts with the N-terminal tail of histone H3, and an ATPase domain; relocalizes to the cytosol in response to hypoxia; potentially phosphorylated by Cdc28p [Source:SGD;Acc:S000003502]" Bcin10g02820 233 DSBA-like thioredoxin domain + Thioredoxin-like fold + HCCA isomerase/glutathione S-transferase kappa Bcin10g02830 314 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin10g02840 597 tRNA-dihydrouridine synthase + Aldolase-type TIM barrel + tRNA-dihydrouridine synthase, conserved site Bcin10g02850 856 "Bcbni4, similar to yeast BNI4, Targeting subunit for Glc7p protein phosphatase; localized to the bud neck, required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p [Source:SGD;Acc:S000005177]" Bcin10g02860 353 "Bcswc5, similar to yeast SWC5, Component of the SWR1 complex; complex exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000000435]" Bcin10g02870 419 Phospholipid/glycerol acyltransferase + Acyltransferase, C-terminal domain Bcin10g02880 422 "Bcpos5, similar to yeast POS5, Mitochondrial NADH kinase; phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress [Source:SGD;Acc:S000006109]" Bcin10g02890 154 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin10g02900 506 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin10g02910 119 Bcin10g02920 527 Transporter//Effector(V2)|Effector(V1) Major facilitator superfamily + Major facilitator superfamily domain Bcin10g02930 323 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin10g02940 366 "Bcstb3, similar to yeast STB3, Ribosomal RNA processing element (RRPE)-binding protein; involved in the glucose-induced transition from quiescence to growth; restricted to nucleus in quiescent cells, released into cytoplasm after glucose repletion; binds Sin3p; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000002576]" Bcin10g02950 665 "Bctop3, similar to yeast TOP3, DNA Topoisomerase III; conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially; DNA catenation/decatenation activity stimulated by RPA and Sgs1p-Top2p-Rmi1p; involved in telomere stability and regulation of mitotic recombination [Source:SGD;Acc:S000004224]" Bcin10g02960 353 Protein of unknown function DUF1295 Bcin10g02970 336 Bcin10g02980 680 Bcin10g02990 684 "Bccwc22, similar to yeast CWC22, Spliceosome-associated protein that is required for pre-mRNA splicing; necessary for Prp2p function at the first catalytic step of splicing; has similarity to S. pombe Cwf22p; CWC22 is an essential protein [Source:SGD;Acc:S000003510]" Bcin10g03000 89 Effector(V1) Dolichol phosphate-mannose biosynthesis regulatory Bcin10g03010 1134 Bcin10g03020 487 Bcin10g03030 332 Bcin10g03040 412 CAZy : GTnc Capsular polysaccharide synthesis + Nucleotide-diphospho-sugar transferases Bcin10g03050 371 Effector(V2) Protein kinase-like domain + Protein of unknown function DUF227 Bcin10g03060 325 Bcin10g03070 370 Bcin10g03080 213 Bcin10g03090 616 "Bchem1, similar to yeast HEM1, 5-aminolevulinate synthase; catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p [Source:SGD;Acc:S000002640]" Bcin10g03100 537 Bcin10g03110 412 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin10g03120 641 SignalP-noTM Cupredoxin Bcin10g03130 718 MoaA/nifB/pqqE, iron-sulphur binding, conserved site + Elongator protein 3/MiaB/NifB + Radical SAM + Molybdenum cofactor synthesis C-terminal + Molybdenum cofactor biosynthesis protein A + Aldolase-type TIM barrel + Molybdopterin cofactor biosynthesis C (MoaC) domain + Molybdenum cofactor biosynthesis C, bacterial-type Bcin10g03140 535 WD40-like Beta Propeller + WD40/YVTN repeat-like-containing domain Bcin10g03150 248 Bcebp2, Emopamil-binding protein Bcin10g03160 849 Bcin10g03170 416 "Bctpt1, similar to yeast TPT1, tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing: the transfer of the 2'-PO(4) from the splice junction to NAD(+) to form ADP-ribose 1''-2''cyclic phosphate and nicotinamide [Source:SGD;Acc:S000005462]" Bcin10g03180 942 Bcin10g03190 751 Dual specificity phosphatase, catalytic domain + Protein-tyrosine/Dual specificity phosphatase + Protein-tyrosine phosphatase, active site + Dual specificity phosphatase, subgroup, catalytic domain + Dual specificity phosphatase + Protein-tyrosine phosphatase-like Bcin10g03200 307 Double-stranded RNA-binding domain Bcin10g03210 555 Protease Peptidase M24, structural domain + Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site + Aminopeptidase P, N-terminal + Creatinase/Aminopeptidase P, N-terminal + Creatinase/Aminopeptidase P/Spt16, N-terminal Bcin10g03220 572 Bcin10g03230 761 Rab-GTPase-TBC domain Bcin10g03240 371 K Homology domain + K Homology domain, type 1 Bcin10g03250 146 Effector(V2)|Effector(V1) Actin-depolymerising factor homology domain + ADF-H/Gelsolin-like domain Bcin10g03260 424 "Bchut1, similar to yeast HUT1, Protein with a role in UDP-galactose transport to the Golgi lumen; has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1 [Source:SGD;Acc:S000006165]" Bcin10g03270 736 Heterokaryon incompatibility Bcin10g03280 1217 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain Bcin10g03290 703 Leucine-rich repeat + F-box domain + Leucine-rich repeat, cysteine-containing subtype + Leucine-rich repeat domain, L domain-like Bcin10g03300 864 Pentatricopeptide repeat Bcin10g03310 517 Transporter Histidine phosphatase superfamily, clade-2 + Histidine phosphatase superfamily + Histidine acid phosphatase active site Bcin10g03320 317 Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin10g03330 512 "Bcmss51, similar to yeast MSS51, Specific translational activator for the mitochondrial COX1 mRNA; loosely associated with the matrix face of the mitochondrial inner membrane; localizes to vacuole membrane in response to H2O2; influences both COX1 mRNA translation and Cox1p assembly into cytochrome c oxidase; binds to heme B, which may be a mechanism for sensing oxygen levels in order to regulate cytochrome c oxidase biogenesis [Source:SGD;Acc:S000004193]" Bcin10g03340 1212 "Bcrse1, similar to yeast RSE1, Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; involved in ER to Golgi transport [Source:SGD;Acc:S000004513]" Bcin10g03350 324 Zinc finger, RING/FYVE/PHD-type + LysM domain Bcin10g03360 340 Bcin10g03370 1468 Ankyrin repeat + Ankyrin repeat-containing domain Bcin10g03380 250 Oxoglutarate/iron-dependent dioxygenase + Alpha-ketoglutarate-dependent dioxygenase AlkB-like + Alpha-ketoglutarate-dependent dioxygenase alkB homologue 6 Bcin10g03390 309 "Bcdfg10, similar to yeast DFG10, Probable polyprenol reductase; catalyzes conversion of polyprenol to dolichol, the precursor for N-glycosylation; involved in filamentous growth; mutations in human ortholog SRD5A3 confer CDG (Congenital Disorders of Glycosylation) [Source:SGD;Acc:S000001311]" Bcin10g03400 367 "Bcrbg1, similar to yeast RBG1, Member of the DRG family of GTP-binding proteins; associates with translating ribosomes; interacts with Tma46p, Ygr250cp, Gir2p and Yap1p via two-hybrid [Source:SGD;Acc:S000000034]" Bcin10g03410 597 HTH CenpB-type DNA-binding domain + DNA binding HTH domain, Psq-type + Homeodomain-like Bcin10g03420 594 Phox-associated domain Bcin10g03430 1433 SNF2-related + Bromodomain + Helicase, C-terminal + Helicase superfamily 1/2, ATP-binding domain + Helicase/SANT-associated, DNA binding + Glutamine-Leucine-Glutamine, QLQ + Bromodomain, conserved site + P-loop containing nucleoside triphosphate hydrolase + Snf2 ATP coupling domain Bcin10g03440 1234 "Bcctr9, similar to yeast CTR9, Component of the Paf1p complex involved in transcription elongation; binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cyclin genes; involved in SER3 repression by helping to maintain SRG1 transcription-dependent nucleosome occupancy; contains TPR repeats [Source:SGD;Acc:S000005505]" Bcin10g03450 265 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Protein of unknown function DUF3455 Bcin10g03460 760 "Bccoy1, similar to yeast COY1, Golgi membrane protein with similarity to mammalian CASP; genetic interactions with GOS1 (encoding a Golgi snare protein) suggest a role in Golgi function [Source:SGD;Acc:S000001662]" Bcin10g03470 1186 Citron-like + Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 Bcin10g03480 752 Ubiquitin-related domain Bcin10g03490 564 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain + L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase Bcin10g03500 563 "Bcpsd1, similar to yeast PSD1, Phosphatidylserine decarboxylase of the mitochondrial inner membrane; converts phosphatidylserine to phosphatidylethanolamine; regulates mitochondrial fusion and morphology by affecting lipid mixing in the mitochondrial membrane and by influencing the ratio of long to short forms of Mgm1p; partly exposed to the mitochondrial intermembrane space [Source:SGD;Acc:S000005113]" Bcin10g03510 155 Proteasome assembly chaperone 4 Bcin10g03520 944 "Bckap104, similar to yeast KAP104, Transportin or cytosolic karyopherin beta 2; functions in the rg-nuclear localization signal-mediated nuclear import/reimport of mRNA-binding proteins Nab2p and Hrp1p; regulates asymmetric protein synthesis in daughter cells during mitosis [Source:SGD;Acc:S000000221]" Bcin10g03530 547 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin10g03540 319 Protease Peptidase C12, ubiquitin carboxyl-terminal hydrolase + Ubiquitinyl hydrolase, UCH37 type Bcin10g03550 552 Protein of unknown function DUF2985 Bcin10g03560 612 "Bcvts1, similar to yeast VTS1, Flap-structured DNA-binding and RNA-binding protein; stimulates deadenylation-dependent mRNA degradation mediated by the CCR4-NOT deadenylase complex; member of the Smaug (Smg) family of post-transcriptional regulators which bind RNA through a conserved sterile alpha motif (SAM) domain that interacts with Smg recognition element (SREs) containing transcripts; stimulates Dna2p endonuclease activity [Source:SGD;Acc:S000005886]" Bcin10g03570 110 Bcin10g03580 65 "Bcrpl29, similar to yeast RPL29, Ribosomal 60S subunit protein L29; not essential for translation, but required for proper joining of large and small ribosomal subunits and for normal translation rate; homologous to mammalian ribosomal protein L29, no bacterial homolog [Source:SGD;Acc:S000006437]" Bcin10g03590 338 Transporter Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin10g03600 853 Protease Peptidase C2, calpain, catalytic domain + Peptidase C2, calpain, large subunit, domain III + Peptidase C2, calpain, domain III Bcin10g03610 481 Cys2His2 transcription factor Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin10g03620 424 SignalP-noTM Nucleotide-sugar transporter + Nucleotide-sugar transporter-related Bcin10g03630 1306 "Bcclu1, similar to yeast CLU1, Subunit of the eukaryotic translation initiation factor 3 (eIF3); component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation; can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant [Source:SGD;Acc:S000004614]" Bcin10g03640 874 Bcin10g03650 613 SignalP-noTM FAD-binding 8 + Ferric reductase, NAD binding + Ferric reductase transmembrane component-like domain + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel Bcin10g03660 110 Effector(V2)|Effector(V1) Yippee/Mis18 Bcin10g03670 196 tRNA intron endonuclease, catalytic domain-like + tRNA-splicing endonuclease subunit Sen15 Bcin10g03680 1035 "Bctfc4, similar to yeast TFC4, Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA domain of TFIIIC that binds BoxA DNA promoter sites of tRNA and similar genes; has TPR motifs; human homolog is TFIIIC-102 [Source:SGD;Acc:S000003279]" Bcin10g03690 410 Bcin10g03700 458 Bcin10g03710 145 Bcin10g03720 346 "Bcmtw1, similar to yeast MTW1, Essential component of the MIND kinetochore complex; joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly; complex consists of Mtw1p Including Nnf1p-Nsl1p-Dsn1p (MIND) [Source:SGD;Acc:S000000032]" Bcin10g03730 763 SignalP-noTM Tail specific protease + ClpP/crotonase-like domain Bcin10g03740 374 Bcin10g03750 230 Effector(V2) Dcp1-like decapping + Pleckstrin homology-like domain Bcin10g03760 1044 "Bcinp51, similar to yeast INP51, Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth [Source:SGD;Acc:S000001264]" Bcin10g03770 452 SignalP-noTM Histidine phosphatase superfamily, clade-2 + Histidine acid phosphatase, eukaryotic + Histidine phosphatase superfamily Bcin10g03780 433 "Bcpdx1, similar to yeast PDX1, E3-binding protein of the mitochondrial pyruvate dehydrogenase complex; plays a structural role in the complex by binding and positioning dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide acetyltransferase (E2) core [Source:SGD;Acc:S000003425]" Bcin10g03790 288 Bcin10g03800 856 Leucine-rich repeat + Leucine-rich repeat, typical subtype + Leucine-rich repeat domain, L domain-like Bcin10g03810 251 Bcin10g03820 1053 "Bcrpg1, similar to yeast RPG1, eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3); subunit of the core complex of eIF3; essential for translation; part of a Prt1p-Rpg1p-Nip1p subcomplex that stimulates binding of mRNA and tRNA(i)Met to ribosomes; involved in translation reinitiation [Source:SGD;Acc:S000000283]" Bcin10g03830 268 Selenoprotein, Rdx type + Thioredoxin-like fold Bcin10g03840 94 Effector(V2)|Effector(V1) Bcgg1, Heterotrimeric G? subunit Bcin10g03850 574 Heterokaryon incompatibility Bcin10g03860 406 SignalP-noTM Protein of unknown function DUF3431 Bcin10g03870 856 Bclov3, PAS/ LOV protein 3, putative blue light sensor Bcin10g03880 966 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin10g03890 379 P-loop containing nucleoside triphosphate hydrolase Bcin10g03900 382 Mitochondrial homologous recombination protein 1 Bcin10g03910 946 "Bchsp104, similar to yeast HSP104, Disaggregase; heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured, aggregated proteins; responsive to stresses including: heat, ethanol, and sodium arsenite; involved in [PSI+] propagation; protein becomes more abundant and forms cytoplasmic foci in response to DNA replication stress; potentiated Hsp104p variants decrease TDP-43 proteotoxicity by eliminating its cytoplasmic aggregation [Source:SGD;Acc:S000003949]" Bcin10g03920 451 Proteasome component (PCI) domain + Winged helix-turn-helix DNA-binding domain + 26S proteasome, regulatory subunit Rpn7 + COP9 signalosome complex subunit 1 Bcin10g03930 322 Calcineurin-like phosphoesterase domain, apaH type + Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase + Metallo-dependent phosphatase-like + Serine-threonine protein phosphatase, N-terminal Bcin10g03940 1225 siRNA-mediated silencing protein NRDE-2 Bcin10g03950 1799 "Bcutp10, similar to yeast UTP10, Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA; mutant has increased aneuploidy tolerance [Source:SGD;Acc:S000003645]" Bcin10g03960 962 "Bcrdh54, similar to yeast RDH54, DNA-dependent ATPase; DNA recombination/repair translocase, supercoils DNA and promotes DNA strand opening; stimulates strand exchange by modifying dsDNA topology; involved in recombinational repair of DNA double-strand breaks (DSBs) during mitosis and meiosis; phosphorylated in Mec1p-, Rad53p-dependent way in response to one DSB; contributes to remodelling of nucleosomes; proposed to be involved in crossover interference; interacts with Dmc1p; stimulates Dmc1p and Rad51p [Source:SGD;Acc:S000000277]" Bcin10g03970 696 "Bcsec63, similar to yeast SEC63, Essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; other members are Sec63p, Sec62p, Sec66p and Sec72p [Source:SGD;Acc:S000005780]" Bcin10g03980 631 Protein of unknown function DUF2347 + Domain of unknown function DUF4484 Bcin10g03990 457 Bcin10g04000 565 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin10g04010 206 Bcin10g04020 1573 Villin/Gelsolin + Domain of unknown function DUF4045 + ADF-H/Gelsolin-like domain + Protein flightless-1 Bcin10g04030 181 "Bccin4, similar to yeast CIN4, GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl; regulated by the GTPase-activating protein, Cin2p, the human retinitis pigmentosa 2 (RP2) homolog [Source:SGD;Acc:S000004746]" Bcin10g04040 1010 Acyl-CoA N-acyltransferase Bcin10g04050 801 "Bcdrs1, similar to yeast DRS1, Nucleolar DEAD-box protein required for ribosome assembly and function; including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles [Source:SGD;Acc:S000003931]" Bcin10g04060 1075 Zn2/Cys6 + fungal trans transcription factor Bcftf1, Zn2/Cys6 transcription factor Bcin10g04070 291 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin10g04080 347 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin10g04090 946 Domain of unknown function DUF2235 + Alpha/Beta hydrolase fold Bcin10g04100 454 N2227-like + S-adenosyl-L-methionine-dependent methyltransferase Bcin10g04110 573 "Bcpap1, similar to yeast PAP1, Poly(A) polymerase; one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs; required for gene looping [Source:SGD;Acc:S000001710]" Bcin10g04120 855 "Bcapp1, similar to yeast APP1, Phosphatidate phosphatase, converts phosphatidate to diacylglycerol; App1p, Pah1p, Dpp1p, and Lpp1p are responsible for all the phosphatidate phosphatase activity; component of cortical actin patches; interacts with components of endocytic pathway [Source:SGD;Acc:S000005038]" Bcin10g04130 340 "Bcfsf1, similar to yeast FSF1, Putative protein; predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis [Source:SGD;Acc:S000005797]" Bcin10g04140 676 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin10g04150 946 "Bctrz1, similar to yeast TRZ1, tRNA 3'-end processing endonuclease tRNase Z; also localized to mitochondria and interacts genetically with Rex2 exonuclease; homolog of the human candidate prostate cancer susceptibility gene ELAC2 [Source:SGD;Acc:S000001787]" Bcin10g04160 491 Bcin10g04170 129 Effector(V1) Bcin10g04180 431 Bcin10g04190 713 Glyoxal oxidase, N-terminal + Galactose oxidase/kelch, beta-propeller + Immunoglobulin-like fold + Immunoglobulin E-set + Domain of unknown function DUF1929 + Galactose oxidase, beta-propeller Bcin10g04200 169 Effector(V2)|Effector(V1) Cytochrome P450 Bcin10g04210 741 Bcin10g04220 169 Effector(V1) "Bctma19, similar to yeast TMA19, Protein that associates with ribosomes; homolog of translationally controlled tumor protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and relocates to the mitochondrial outer surface upon oxidative stress [Source:SGD;Acc:S000001539]" Bcin10g04230 364 Fatty acid hydroxylase Bcin10g04240 469 Bcin10g04250 918 Fungal trans transcription factor Transcription factor domain, fungi Bcin10g04260 322 Bcin10g04270 490 Bcin10g04280 842 Leucine-rich repeat domain, L domain-like Bcin10g04290 187 Effector(V1) Ribosomal protein L22/L17 + Ribosomal protein L22/L17, eukaryotic/archaeal + Ribosomal protein L22/L17, conserved site Bcin10g04300 156 Ribosomal protein S13 + Ribosomal protein S13-like, H2TH + Ribosomal protein S13, conserved site + 30s ribosomal protein S13, C-terminal Bcin10g04310 308 Ribosome maturation protein SBDS + Ribosome maturation protein SBDS, C-terminal + Ribosome maturation protein SBDS, N-terminal Bcin10g04320 546 Protease//SignalP-noTM Bccp4, Serine carboxypeptidase Bcin10g04330 590 Protease//SignalP-noTM//Early secretome Peptidase S10, serine carboxypeptidase + Alpha/Beta hydrolase fold Bcin10g04340 902 Cas1p 10 TM acyl transferase domain Bcin10g04350 516 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin10g04360 666 CAZy : GH127 Six-hairpin glycosidase-like + Six-hairpin glycosidase + Protein of unknown function DUF1680 Bcin10g04370 473 ELO family Bcin10g04380 598 Bcin10g04390 446 Nucleotide-binding alpha-beta plait domain + Protein of unknown function DUF2414 Bcin10g04400 362 Bcltf12, Light-responsive Myb-type transcription factor Bcin10g04410 257 "Bcdal3, similar to yeast DAL3, Ureidoglycolate lyase; converts ureidoglycolate to glyoxylate and urea in the third step of allantoin degradation; expression is sensitive to nitrogen catabolite repression; this enzyme is sometimes referred to ureidoglycolate hydrolase but should not be confused with the Arabidopsis thaliana ureidoglycolate hydrolase enzyme which converts ureidoglycolate to glyoxylate, ammonia and carbon dioxide [Source:SGD;Acc:S000001471]" Bcin10g04420 490 Myb-like domain Bcin10g04430 122 Effector(V1) Major facilitator superfamily domain Bcin10g04440 200 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin10g04450 520 Bcin10g04460 158 Bcin10g04470 369 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin10g04480 1388 P-loop containing nucleoside triphosphate hydrolase + Alpha/Beta hydrolase fold Bcin10g04490 325 Bcin10g04500 206 Effector(V1) Bcin10g04510 547 Zinc finger, CCHC-type + DDE superfamily endonuclease, CENP-B-like + HTH CenpB-type DNA-binding domain + DNA binding HTH domain, Psq-type + Homeodomain-like Bcin10g04520 298 Bcin10g04530 1959 Bcin10g04540 583 Dynactin subunit 4 Bcin10g04550 322 "Bcnop1, similar to yeast NOP1, Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; ortholog of mammalian fibrillarin [Source:SGD;Acc:S000002172]" Bcin10g04560 239 SignalP-noTM//Effector(V2)|Effector(V1) Bcin10g04570 264 yes SignalP-noTM BcHsbA3, hydrophobic surface binding protein Bcin10g04580 773 von Willebrand factor, type A + Zinc finger, Sec23/Sec24-type + Sec23/Sec24, trunk domain + Sec23/Sec24, helical domain + Gelsolin-like domain + Sec23/Sec24 beta-sandwich + ADF-H/Gelsolin-like domain Bcin10g04590 165 Effector(V2)|Effector(V1) Ribosomal protein L11/L12 + Ribosomal protein L11, C-terminal + Ribosomal protein L11, N-terminal + Ribosomal protein L11, conserved site Bcin10g04600 1576 CAZy : GT41 Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Tetratricopeptide repeat + O-GlcNAc transferase, C-terminal Bcin10g04610 201 Effector(V1) Ribosomal protein S7e Bcin10g04620 664 WD40 repeat + F-box domain + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin10g04630 171 Bcin10g04640 516 Bcin10g04650 469 Domain of unknown function DUF89 Bcin10g04660 1252 Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily + GAF domain-like Bcin10g04670 94 Effector(V2)|Effector(V1) NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 Bcin10g04680 494 "Bcpop2, similar to yeast POP2, RNase of the DEDD superfamily; subunit of the Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation [Source:SGD;Acc:S000005335]" Bcin10g04690 349 "Bcfaf1, similar to yeast FAF1, Protein required for pre-rRNA processing; also required for 40S ribosomal subunit assembly [Source:SGD;Acc:S000001281]" Bcin10g04700 260 "Bchis6, similar to yeast HIS6, Enzyme that catalyzes the fourth step in the histidine pathway; Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts [Source:SGD;Acc:S000001282]" Bcin10g04710 567 Bcin10g04720 194 Bcin10g04730 276 Bcin10g04740 103 Effector(V2)|Effector(V1) Bcin10g04750 442 Bcin10g04760 384 Bcin10g04770 551 Bcin10g04780 160 Effector(V2)|Effector(V1) Ricin B lectin domain Bcin10g04790 608 Bcin10g04800 252 Bcin10g04810 498 Major facilitator superfamily + Major facilitator superfamily domain Bcin10g04820 660 Transporter "Bcnhx1, similar to yeast NHX1, Na+/H+ and K+/H+ exchanger; required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion; ortholog of human NHE9, which is linked to autism [Source:SGD;Acc:S000002864]" Bcin10g04830 614 Transporter Major facilitator superfamily domain Bcin10g04840 988 Bcin10g04850 201 Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Tetratricopeptide TPR2 + Tetratricopeptide repeat Bcin10g04860 450 Bcin10g04870 206 Bcin10g04880 545 Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin10g04890 530 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 + S-adenosyl-L-methionine-dependent methyltransferase Bcin10g04900 304 Protease "Bcyju3, similar to yeast YJU3, Monoglyceride lipase (MGL); functional ortholog of mammalian MGL, localizes to lipid particles and membranes, also member of the eukaryotic serine hydrolase family [Source:SGD;Acc:S000001577]" Bcin10g04910 419 Bcin10g04920 239 Protease//Effector(V2)|Effector(V1) ATP-dependent Clp protease proteolytic subunit + ClpP, active site + Clp protease proteolytic subunit /Translocation-enhancing protein TepA + ClpP/crotonase-like domain + ClpP, histidine active site Bcin10g04930 746 Bcin10g04940 302 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin10g04950 468 "Bcytp1, similar to yeast YTP1, Probable type-III integral membrane protein of unknown function; has regions of similarity to mitochondrial electron transport proteins [Source:SGD;Acc:S000005181]" Bcin10g04960 319 "Bcpth1, similar to yeast PTH1, One of two mitochondrially-localized peptidyl-tRNA hydrolases; dispensable for respiratory growth on rich medium, but required for respiratory growth on minimal medium; see also PTH2 [Source:SGD;Acc:S000001232]" Bcin10g04970 216 Effector(V1) Marvel domain Bcin10g04980 213 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Bcin10g04990 381 BAR domain + Arfaptin homology (AH) domain/BAR domain + Amphiphysin Bcin10g05000 106 Effector(V1) Bcin10g05010 447 CAZy : GH28PCW pectin//SignalP-noTM Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin10g05020 343 SignalP-noTM Bcin10g05030 139 Bcin10g05040 247 "Bcubc1, similar to yeast UBC1, Ubiquitin-conjugating enzyme; key E2 partner with Ubc4p for the anaphase-promoting complex (APC); mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response; protein abundance increases in response to DNA replication stress key E2 partner with Ubc4p for the anaphase-promoting complex (APC) [Source:SGD;Acc:S000002584]" Bcin10g05050 466 "Bcrpt2, similar to yeast RPT2, ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle; N-myristoylation of Rpt2p at Gly2 is involved in regulating the proper intracellular distribution of proteasome activity by controlling the nuclear localization of the 26S proteasome [Source:SGD;Acc:S000002165]" Bcin10g05060 1755 Ankyrin repeat + Ankyrin repeat-containing domain Bcin10g05070 198 Bcin10g05080 1126 Bcin10g05090 165 Effector(V1) "Bcatp16, similar to yeast ATP16, Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; F1 translationally regulates ATP6 and ATP8 expression to achieve a balanced output of ATP synthase genes encoded in nucleus and mitochondria; phosphorylated [Source:SGD;Acc:S000002162]" Bcin10g05100 781 Protein of unknown function DUF2457 Bcin10g05110 494 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin10g05120 483 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin10g05130 276 NAD(P)-binding domain Bcin10g05140 1577 DNA repair protein, Swi5 + AT hook, DNA-binding motif Bcin10g05150 246 Effector(V1) "Bctif6, similar to yeast TIF6, Constituent of 66S pre-ribosomal particles; has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits [Source:SGD;Acc:S000006220]" Bcin10g05160 223 Effector(V2)|Effector(V1) Bcin10g05170 790 Bcin10g05180 376 "Bcrad23, similar to yeast RAD23, Protein with ubiquitin-like N terminus; subunit of Nuclear Excision Repair Factor 2 (NEF2) with Rad4p that binds damaged DNA; enhances protein deglycosylation activity of Png1p; also involved, with Rad4p, in ubiquitylated protein turnover [Source:SGD;Acc:S000000763]" Bcin10g05190 481 Bcin10g05200 443 Bcin10g05210 335 Bcin10g05220 105 Bcin10g05230 494 "Bcuga1, similar to yeast UGA1, Gamma-aminobutyrate (GABA) transaminase; also known as 4-aminobutyrate aminotransferase; involved in the 4-aminobutyrate and glutamate degradation pathways; required for normal oxidative stress tolerance and nitrogen utilization; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003251]" Bcin10g05240 332 Bcin10g05250 953 "Bcset2, similar to yeast SET2, Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36 (H3K36), which suppresses incorporation of acetylated histones and signals for the deacetylation of these histones within transcribed genes; associates with the C-terminal domain(CTD) of Rpo21p; H3K36me3 (trimethylation) requires Spt6p, proline 38 on H3, CTD of Rpo21p, Ctk1p, and C-terminal SRI domain of Ste2p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003704]" Bcin10g05260 733 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin10g05270 284 Effector(V2) AhpD-like Bcin10g05280 498 Ergosterol biosynthesis ERG4/ERG24 + Sterol reductase, conserved site Bcin10g05290 670 Bcin10g05300 900 Zinc finger, LIM-type Bcin10g05310 368 Early secretome "Bcleu2, similar to yeast LEU2, Beta-isopropylmalate dehydrogenase (IMDH); catalyzes the third step in the leucine biosynthesis pathway; can additionally catalyze the conversion of β-ethylmalate into α-ketovalerate [Source:SGD;Acc:S000000523]" Bcin10g05320 704 Zinc finger, PHD-type + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, PHD-type, conserved site + Zinc finger, PHD-finger Bcin10g05330 638 Protein of unknown function DUF4451 Bcin10g05340 311 Bcin10g05350 174 Effector(V2)|Effector(V1) Bcin10g05360 585 Major facilitator superfamily + Major facilitator superfamily domain Bcin10g05370 488 Aminotransferase class-III + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin10g05380 162 Effector(V2)|Effector(V1) "Bcnut2, similar to yeast NUT2, Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for transcriptional activation and has a role in basal transcription; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006372]" Bcin10g05390 294 "Bcefm4, similar to yeast EFM4, Lysine methyltransferase; involved in the dimethylation of eEF1A (Tef1p/Tef2p) at lysine 316; sequence similarity to S-adenosylmethionine-dependent methyltransferases of the seven beta-strand family; role in vesicular transport [Source:SGD;Acc:S000001326]" Bcin10g05400 617 "Bctpd3, similar to yeast TPD3, Regulatory subunit A of the heterotrimeric PP2A complex; the heterotrimeric protein phosphatase 2A (PP2A) complex also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and transcription by RNA polymerase III [Source:SGD;Acc:S000000014]" Bcin10g05410 609 "Bcfrs1, similar to yeast FRS1, Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase; forms a tetramer with Frs2p to generate active enzyme; able to hydrolyze mis-aminoacylated tRNA-Phe, which could contribute to translational quality control [Source:SGD;Acc:S000004050]" Bcin10g05420 787 "Bcymr1, similar to yeast YMR1, Phosphatidylinositol 3-phosphate (PI3P) phosphatase; involved in various protein sorting pathways, including CVT targeting and endosome to vacuole transport; has similarity to the conserved myotubularin dual specificity phosphatase family [Source:SGD;Acc:S000003871]" Bcin10g05430 263 Effector(V1)//Early secretome "Bcrps3, similar to yeast RPS3, Protein component of the small (40S) ribosomal subunit; has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; homologous to mammalian ribosomal protein S3 and bacterial S3 [Source:SGD;Acc:S000005122]" Bcin10g05440 407 Magnesium transporter NIPA Bcin10g05450 890 Uncharacterised protein family UPF0646 Bcin10g05460 515 "Bcret2, similar to yeast RET2, Delta subunit of the coatomer complex (COPI); COPI coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER [Source:SGD;Acc:S000001947]" Bcin10g05470 779 WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + Anaphase-promoting complex subunit 4 + Anaphase-promoting complex subunit 4 long domain + Anaphase-promoting complex subunit 4, WD40 domain Bcin10g05480 537 Transporter Amino acid/polyamine transporter I Bcin10g05490 724 yes Bcku80, Protein involved in DNA reparation Bcin10g05500 183 Domain of unknown function DUF4149 Bcin10g05510 1262 "Bcsmc1, similar to yeast SMC1, Subunit of the multiprotein cohesin complex; essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure [Source:SGD;Acc:S000001886]" Bcin10g05520 532 Protein of unknown function DUF2838 Bcin10g05530 573 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin10g05540 1196 Zinc finger, PHD-type + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Enhancer of polycomb-like, N-terminal + Zinc finger, PHD-type, conserved site + Zinc finger, PHD-finger Bcin10g05550 360 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain Bcin10g05560 708 yes Cys2His2 transcription factor//Signaling pathway Bcste12,Bchox9, Cys2His2 and homeobox transcription factor Bcin10g05570 195 Bcin10g05580 311 Bcin10g05590 892 CAZy : GH3PCW/FCW //Early secretome Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Fibronectin type III-like domain Bcin10g05600 379 Bcin10g05610 349 Bcin10g05620 353 CAZy : PL3PCW pectin//SignalP-noTM Pectate lyase, catalytic + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin10g05630 888 CAZy : GH3PCW/FCW //SignalP-noTM Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Glycoside hydrolase, family 3, active site + Fibronectin type III-like domain Bcin10g05640 247 "Bcbim1, similar to yeast BIM1, Microtubule plus end-tracking protein; together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally [Source:SGD;Acc:S000000818]" Bcin10g05650 376 "Bcvam7, similar to yeast VAM7, Vacuolar SNARE protein; functions with Vam3p in vacuolar protein trafficking; has an N-terminal PX domain (phosphoinositide-binding module) that binds PtdIns-3-P and mediates membrane binding; SNAP-25 homolog; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003180]" Bcin10g05660 940 Bcin10g05670 178 Bcin10g05680 559 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin10g05690 897 Bcin10g05700 192 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2) Bcin10g05710 559 CAZy : GH32Energy //SignalP-noTM//Early secretome Glycoside hydrolase, family 32 + Glycosyl hydrolase family 32, N-terminal + Glycosyl hydrolase family 32, C-terminal + Concanavalin A-like lectin/glucanase domain + Glycoside hydrolase, family 32, active site + Glycosyl hydrolase, five-bladed beta-propellor domain Bcin10g05720 609 "Bccdh1, similar to yeast CDH1, Activator of anaphase-promoting complex/cyclosome (APC/C); cell-cycle regulated; directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p [Source:SGD;Acc:S000002971]" Bcin10g05730 841 Ribonuclease H-like domain Bcin10g05740 106 Effector(V2)|Effector(V1) "Bcmdj2, similar to yeast MDJ2, Constituent of the mitochondrial import motor; associated with the presequence translocase; function overlaps with that of Pam18p; stimulates the ATPase activity of Ssc1p to drive mitochondrial import; contains a J domain [Source:SGD;Acc:S000005272]" Bcin10g05750 142 Bcin10g05760 1019 Armadillo-like helical + Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Armadillo-type fold + Domain of unknown function DUF4470 Bcin10g05770 831 Clathrin/coatomer adaptor, adaptin-like, N-terminal + Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain + Clathrin adaptor, gamma-adaptin, appendage + Armadillo-like helical + Coatomer/clathrin adaptor appendage, Ig-like subdomain + Armadillo-type fold + Adaptor protein complex AP-1, gamma subunit Bcin10g05780 554 Membrane bound O-acyl transferase, MBOAT + Sterol O-acyltransferase, ACAT/DAG/ARE types Bcin10g05790 92 Bcin10g05800 674 DnaJ domain + DnaJ domain, conserved site Bcin10g05810 66 Effector(V2)|Effector(V1) Bcin10g05820 162 Effector(V1) Bcin10g05830 369 Bcin10g05840 578 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin10g05850 519 Alcohol acetyltransferase Bcin10g05870 464 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin10g05880 632 "Bcrcm1, similar to yeast RCM1, rRNA m5C methyltransferase; methylates cytosine at position 2278 of 25S rRNA while Nop2p methylates cytosine at position 2870; contains seven beta-strand methyltransferase motif; localized to the nucleolus; interacts with Trm112p; homolog of NSUN5A, a human gene which is deleted in Williams-Beuren Syndrome [Source:SGD;Acc:S000004967]" Bcin10g05890 190 Ribosomal protein L24e-related + TRASH domain Bcin10g05900 681 Fork head transcription factor Forkhead-associated (FHA) domain + Transcription factor, fork head + SMAD/FHA domain + Winged helix-turn-helix DNA-binding domain + Fork head domain conserved site 2 Bcin10g05910 710 SignalP-noTM Bcin10g05920 532 "Bcdml1, similar to yeast DML1, Essential protein involved in mtDNA inheritance; may also function in the partitioning of the mitochondrial organelle or in the segregation of chromosomes, exhibits regions similar to members of a GTPase family [Source:SGD;Acc:S000004824]" Bcin10g05930 189 Bcprx6, Peroxiredoxin Bcin10g05940 145 Effector(V1) Polyketide cyclase SnoaL-like domain + NTF2-like domain Bcin10g05950 626 yes Cys2His2 transcription factor//Signaling pathway BcpacC, C2H2 transcription factor, pH regulator Bcin10g05960 705 Bcin10g05970 987 Zinc finger, PHD-type + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, PHD-type, conserved site + Zinc finger, PHD-finger + Inhibitor of growth protein, N-terminal + ING family Bcin10g05980 378 Bcin10g05990 431 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain Bcin10g06000 198 Effector(V2)|Effector(V1) Protein of unknown function DUF3602 Bcin10g06010 328 Hyaluronan/mRNA-binding protein + Stm1, N-terminal Bcin10g06020 385 Bzip transcription factor Basic-leucine zipper domain Bcin10g06030 338 SignalP-noTM//Effector(V2) "Bcmrl1, similar to yeast MRL1, Membrane protein; has similarity to mammalian mannose-6-phosphate receptors; possibly functions as a sorting receptor in the delivery of vacuolar hydrolases; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006283]" Bcin10g06040 187 Effector(V2)|Effector(V1) Bcin10g06050 245 Bcin10g06060 104 Effector(V2) Bcin10g06070 406 Ysc84 actin-binding domain Bcin10g06080 710 Bcplc2, Phospholipase C Bcin10g06090 99 RmlC-like cupin domain + RmlC-like jelly roll fold Bcin10g06100 1387 Bcin10g06110 547 Cation/H+ exchanger Bcin10g06120 172 Effector(V2)|Effector(V1) Bcin10g06130 432 SignalP-noTM//Early secretome Glycoside hydrolase, family 28 + Parallel beta-helix repeat + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin10g06140 227 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa LysM domain Bcin10g06150 195 Effector(V1) Interferon alpha-inducible protein 6/27 Bcin10g06160 232 Bcin10g06170 466 Bcin10g06180 760 Bcin10g06190 195 Bcin10g06200 1128 Bcin10g06210 299 Bcin10g06220 302 Bcin10g06230 514 Conserved hypothetical protein CHP02464 Bcin10g06240 1141 SNF2-related + Helicase, C-terminal + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin10g06250 1480 Bcin10g06260 471 Bcin10g06270 261 Bcin11g00010 675 SignalP-noTM Glycoside hydrolase, family 1 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin11g00020 494 Protease Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin11g00030 300 NmrA-like domain + NAD(P)-binding domain Bcin11g00040 413 SignalP-noTM FAD linked oxidase, N-terminal + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin11g00050 346 Bcin11g00060 572 Transporter "Bcagp2, similar to yeast AGP2, Plasma membrane regulator of polyamine and carnitine transport; has similarity to transporters but lacks transport activity; may act as a sensor that transduces environmental signals; has a positive or negative regulatory effect on transcription of many transporter genes [Source:SGD;Acc:S000000336]" Bcin11g00070 103 Effector(V1) Bcin11g00080 353 Amidohydrolase 1 + Metal-dependent hydrolase Bcin11g00090 293 Effector(V2) Dienelactone hydrolase + Alpha/Beta hydrolase fold Bcin11g00100 731 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin11g00110 169 Bcin11g00120 629 "Bcaim10, similar to yeast AIM10, Protein with similarity to tRNA synthetases; non-tagged protein is detected in purified mitochondria; null mutant is viable and displays elevated frequency of mitochondrial genome loss [Source:SGD;Acc:S000000889]" Bcin11g00130 1019 CCAAT transcription factor "Bcmak21, similar to yeast MAK21, Constituent of 66S pre-ribosomal particles; required for large (60S) ribosomal subunit biogenesis; acts as part of a Mak21p-Noc2p-Rrp5p module that associates with nascent pre-rRNA during transcription and has a role in bigenesis of the large ribosomal subunit; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein [Source:SGD;Acc:S000002467]" Bcin11g00140 144 Bcin11g00150 304 Thioesterase superfamily + HotDog domain Bcin11g00160 205 Effector(V1) "Bcmet14, similar to yeast MET14, Adenylylsulfate kinase; required for sulfate assimilation and involved in methionine metabolism [Source:SGD;Acc:S000001484]" Bcin11g00170 395 "Bcvma5, similar to yeast VMA5, Subunit C of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane; the V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase) has eight subunits [Source:SGD;Acc:S000001563]" Bcin11g00180 1529 Bcin11g00190 428 Domain of unknown function DUF2236 Bcin11g00200 349 Bcin11g00210 594 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin11g00220 260 Modifier of rudimentary, Modr Bcin11g00230 586 yes Bcfrp1, F-box protein Bcin11g00240 449 Bcin11g00250 387 "Bcrad10, similar to yeast RAD10, Single-stranded DNA endonuclease (with Rad1p); cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein [Source:SGD;Acc:S000004560]" Bcin11g00260 528 Transporter Amino acid/polyamine transporter I + Amino acid permease subfamily Bcin11g00270 391 "Bcoms1, similar to yeast OMS1, Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif; multicopy suppressor of respiratory defects caused by OXA1 mutations [Source:SGD;Acc:S000002724]" Bcin11g00280 340 Bcin11g00290 475 Bcin11g00300 328 SignalP-noTM Metallopeptidase, catalytic domain Bcin11g00310 514 SignalP-noTM Bcin11g00320 759 Bcin11g00330 459 "Bcerg13, similar to yeast ERG13, 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase; catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis [Source:SGD;Acc:S000004595]" Bcin11g00340 514 Protease Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin11g00350 369 "Bcpex14, similar to yeast PEX14, Central component of the peroxisomal importomer complex; peroxisomal protein import machinery docking complex component; interacts with both PTS1 (Pex5p) and PTS2 (Pex7p), peroxisomal matrix protein signal recognition factors and membrane receptor Pex13p [Source:SGD;Acc:S000003121]" Bcin11g00360 737 "Bcndc80, similar to yeast NDC80, Component of the kinetochore-associated Ndc80 complex; conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, and kinetochore assembly and clustering; evolutionarily conserved; other members include Ndc80p, Nuf2p, Scp24p, and Spc25p; modified by sumoylation [Source:SGD;Acc:S000001406]" Bcin11g00370 308 Effector(V2)|Effector(V1) "Bcnpl3, similar to yeast NPL3, RNA-binding protein; promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; represses translation initiation by binding eIF4G; required for pre-mRNA splicing; interacts with E3 ubiquitin ligase Bre1p, linking histone ubiquitination to mRNA processing; may have role in telomere maintenance; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in cytoplasm; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002840]" Bcin11g00380 465 "Bcfmp30, similar to yeast FMP30, Protein with a role in maintaining mitochondrial morphology; also involved in maintaining normal cardiolipin levels; mitochondrial inner membrane protein; proposed to be involved in N-acylethanolamine metabolism; related to mammalian N-acylPE-specific phospholipase D [Source:SGD;Acc:S000006024]" Bcin11g00390 306 Bcgst3, Glutathione S-transferase Bcin11g00400 545 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin11g00410 425 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin11g00420 858 "Bcrtt107, similar to yeast RTT107, Protein implicated in Mms22-dependent DNA repair during S phase; involved in recruiting the SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition; relative distribution to nuclear foci increases upon DNA replication stress [Source:SGD;Acc:S000001197]" Bcin11g00430 363 Protein of unknown function DUF4078 Bcin11g00440 364 "Bchom6, similar to yeast HOM6, Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase); dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions [Source:SGD;Acc:S000003900]" Bcin11g00450 126 Effector(V1) Bcin11g00460 282 "Bctrm8, similar to yeast TRM8, Noncatalytic subunit of a tRNA methyltransferase complex; Trm8p and Trm82p comprise an enzyme that catalyzes a methyl-transfer from S-adenosyl-l-methionine to the N(7) atom of guanine at position 46 in tRNA; Trm8 lacks catalytic activity if not bound to Trm82p [Source:SGD;Acc:S000002360]" Bcin11g00470 1240 "Bcmdm1, similar to yeast MDM1, Intermediate filament protein; required for nuclear and mitochondrial transmission to daughter buds; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P) [Source:SGD;Acc:S000004572]" Bcin11g00480 1229 Domain of unknown function DUF1683, C-terminal + Foie gras liver health family 1 Bcin11g00490 491 Transcriptional regulatory protein RXT2, N-terminal Bcin11g00500 209 "Bcopi3, similar to yeast OPI3, Methylene-fatty-acyl-phospholipid synthase; catalyzes the last two steps in phosphatidylcholine biosynthesis; also known as phospholipid methyltransferase [Source:SGD;Acc:S000003834]" Bcin11g00510 340 Effector(V2) "Bcnit2, similar to yeast NIT2, Nit protein; one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member [Source:SGD;Acc:S000003662]" Bcin11g00520 332 Transporter Mitochondrial substrate/solute carrier + Mitochondrial carrier domain + Solute carrier family 25 member 38 Bcin11g00530 547 Bcin11g00540 121 Effector(V1) Prefoldin beta-like + Prefoldin Bcin11g00550 334 Ceramidase Bcin11g00560 888 "Bcsgm1, similar to yeast SGM1, Protein of unknown function; required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus [Source:SGD;Acc:S000003895]" Bcin11g00570 156 Effector(V2)|Effector(V1) "Bcgim5, similar to yeast GIM5, Subunit of the heterohexameric cochaperone prefoldin complex; prefoldin binds specifically to cytosolic chaperonin and transfers target proteins to it; prefoldin complex also localizes to chromatin of actively transcribed genes in the nucleus and facilitates transcriptional elongation [Source:SGD;Acc:S000004559]" Bcin11g00580 681 Bcin11g00590 798 Bromo adjacent homology (BAH) domain + AAA+ ATPase domain + ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin11g00600 483 "Bcprp46, similar to yeast PRP46, Member of the NineTeen Complex (NTC); this complex contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs [Source:SGD;Acc:S000006072]" Bcin11g00610 237 Effector(V2)|Effector(V1) "Bcnas6, similar to yeast NAS6, Assembly chaperone for the 19S proteasome regulatory particle base; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6 [Source:SGD;Acc:S000003464]" Bcin11g00620 566 Bcin11g00630 550 Bcin11g00640 309 Cys2His2 transcription factor Zinc finger, C2H2-like Bcin11g00650 426 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger, C2H2-like Bcin11g00660 385 Cys2His2 transcription factor//Effector(V2) Zinc finger, C2H2-like Bcin11g00670 389 Bcin11g00680 205 AhpD-like Bcin11g00690 546 Copper fist DNA-binding Bcin11g00700 264 "Bcnnt1, similar to yeast NNT1, S-adenosylmethionine-dependent methyltransferase; has a role in rDNA silencing and in lifespan determination [Source:SGD;Acc:S000004275]" Bcin11g00710 531 Bcin11g00720 526 Protein kinase domain + Protein kinase-like domain Bcin11g00730 586 Helix-loop-helix (HLH) transcription factor Myc-type, basic helix-loop-helix (bHLH) domain Bcin11g00740 216 "Bcsft2, similar to yeast SFT2, Tetra-spanning membrane protein found mostly in the late Golgi; non-essential; can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5 [Source:SGD;Acc:S000000198]" Bcin11g00750 1090 Protein of unknown function DM15 + RNA-binding protein Lupus La + Winged helix-turn-helix DNA-binding domain Bcin11g00760 494 Ribosomal RNA methyltransferase FtsJ domain + S-adenosyl-L-methionine-dependent methyltransferase Bcin11g00770 314 Ccc1 family Bcin11g00780 59 Bcin11g00790 345 "Bcckb1, similar to yeast CKB1, Beta regulatory subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases [Source:SGD;Acc:S000002987]" Bcin11g00800 832 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin11g00810 183 Dopa 4,5-dioxygenase + DOPA-like domain Bcin11g00820 345 JmjC domain Bcin11g00830 633 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin11g00840 226 Effector(V1) Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin11g00850 198 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-H2-type Bcin11g00860 741 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin11g00870 250 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin11g00880 215 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin11g00890 251 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-H2-type Bcin11g00900 226 Effector(V1) Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin11g00910 348 Bcin11g00920 434 Bcin11g00930 629 "Bccir2, similar to yeast CIR2, Putative ortholog of human ETF-dH; found in a large supramolecular complex with other mitochondrial dehydrogenases; may have a role in oxidative stress response; ETF-dH is also known as electron transfer flavoprotein dehydrogenase [Source:SGD;Acc:S000005883]" Bcin11g00940 261 SignalP-noTM Bcin11g00950 112 Effector(V1) Bcin11g00960 116 Effector(V2)|Effector(V1) NADH:ubiquinone oxidoreductase, ESSS subunit Bcin11g00970 411 Transporter Aminotransferase, class IV + Branched-chain amino acid aminotransferase II + Aminotransferase, class IV, conserved site Bcin11g00980 971 "Bcscy1, similar to yeast SCY1, Putative kinase; suppressor of GTPase mutant, similar to bovine rhodopsin kinase [Source:SGD;Acc:S000003051]" Bcin11g00990 275 Transporter//Effector(V2) Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin11g01000 1647 "Bcdna2, similar to yeast DNA2, Tripartite DNA replication factor; has single-stranded DNA-dependent ATPase, ATP-dependent nuclease, and helicase activities; tracking protein for flap cleavage during Okazaki fragment maturation; involved in DNA repair and processing of meiotic DNA double strand breaks; required for normal life span; component of telomeric chromatin, with cell-cycle dependent localization; required for telomerase-dependent telomere synthesis; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000001207]" Bcin11g01010 249 Bcin11g01020 438 Fumarylacetoacetase + Fumarylacetoacetase, C-terminal-related + Fumarylacetoacetase, N-terminal Bcin11g01030 795 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin11g01040 194 Effector(V1) Bcin11g01050 486 Effector(V2)|Effector(V1) Homogentisate 1,2-dioxygenase + RmlC-like cupin domain + RmlC-like jelly roll fold Bcin11g01060 517 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin11g01070 171 Effector(V2)|Effector(V1) RmlC-like cupin domain + Cupin 2, conserved barrel + RmlC-like jelly roll fold Bcin11g01080 970 Bcin11g01090 828 SignalP-noTM//Early secretome Bcin11g01100 289 Protein of unknown function DUF2306, membrane Bcin11g01110 297 Effector(V2)|Effector(V1) Bcin11g01120 193 Bcin11g01130 216 Bcin11g01140 137 Effector(V2)|Effector(V1) Bcin11g01150 337 Bcin11g01160 253 Bcin11g01170 148 Bcin11g01180 139 Effector(V1) Bcin11g01190 544 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin11g01200 1073 Ankyrin repeat + Ankyrin repeat-containing domain Bcin11g01210 316 Bcin11g01220 429 Bcin11g01230 164 Bcin11g01240 120 Effector(V2)|Effector(V1) Bcin11g01250 180 Bcin11g01260 305 Bcin11g01270 401 Putative amidoligase enzyme Bcin11g01280 155 "Bccmd1, similar to yeast CMD1, Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca++ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin [Source:SGD;Acc:S000000313]" Bcin11g01290 416 Bcin11g01300 264 Bcin11g01310 566 Protease//SignalP-noTM//Early secretome Alpha/beta hydrolase fold-1 + Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal + Alpha/Beta hydrolase fold Bcin11g01320 183 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin11g01330 229 Effector(V1) "Bcrib5, similar to yeast RIB5, Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway [Source:SGD;Acc:S000000460]" Bcin11g01340 86 Effector(V1) Bcin11g01350 461 "Bcbcs1, similar to yeast BCS1, Protein translocase and chaperone required for Complex III assembly; member of the AAA ATPase family; forms a homo-oligomeric complex in the mitochondrial inner membrane that translocates the C-terminal domain of Rip1p from the matrix across the inner membrane, and then delivers it to an assembly intermediate of respiratory Complex III in an ATP-dependent reaction; also required for assembly of the Qcr10p subunit; mutations in human homolog BCS1L linked to neonatal diseases [Source:SGD;Acc:S000002783]" Bcin11g01360 717 Sulphate anion transporter + STAS domain + Sulphate transporter Bcin11g01370 816 CAZy : GH55FCW //SignalP-noTM//Early secretome Pectin lyase fold/virulence factor + Pectin lyase fold + Pectate lyase superfamily protein Bcin11g01380 266 Bcin11g01390 1073 Putative amidoligase enzyme Bcin11g01400 191 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin11g01410 541 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin11g01420 1083 AMP-dependent synthetase/ligase + Acyl carrier protein-like + Male sterility, NAD-binding + NAD(P)-binding domain + Polyketide synthase, phosphopantetheine-binding domain Bcin11g01430 380 CAZy : GH53PCW hemicellulose or pectin//SignalP-noTM//Early secretome Glycosyl hydrolase family 53 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin11g01440 510 Bcin11g01450 98 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bhp2, Hydrophobin class II Bcin11g01460 163 Effector(V2) Bcin11g01470 147 Bcin11g01480 176 Bcin11g01490 126 Bcin11g01500 127 Bcin11g01510 80 Effector(V1) Bcin11g01520 107 Effector(V1) Bcin11g01530 102 Bcin11g01540 240 Bcin11g01550 232 Effector(V1) Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin11g01560 445 Auxin efflux carrier Bcin11g01570 716 "Bcpuf6, similar to yeast PUF6, Pumilio-homology domain protein; binds the 3' UTR of ASH1 mRNA and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA; required at post-transcriptional step for efficient retrotransposition; absence results in decreased Ty1 Gag:GFP protein levels; co-sediments with the 60S ribosomal subunit and is required for its biogenesis [Source:SGD;Acc:S000002904]" Bcin11g01580 232 RWD domain + Ubiquitin-conjugating enzyme/RWD-like Bcin11g01590 401 Tetratricopeptide-like helical domain + Tetratricopeptide repeat Bcin11g01600 235 Effector(V2) Bcin11g01610 424 Bcin11g01620 349 "Bcrad51, similar to yeast RAD51, Strand exchange protein; forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein [Source:SGD;Acc:S000000897]" Bcin11g01630 1207 Quinoprotein amine dehydrogenase, beta chain-like + WD40/YVTN repeat-like-containing domain + WD40 repeat, conserved site Bcin11g01640 324 "Bcpep8, similar to yeast PEP8, Vacuolar protein component of the retromer; forms part of the multimeric membrane-associated retromer complex involved in vacuolar protein sorting along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport; interacts with Ypt7p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003589]" Bcin11g01650 98 Effector(V1) Ribonucleoprotein LSM domain + Like-Sm (LSM) domain Bcin11g01660 458 Inosine/uridine-preferring nucleoside hydrolase domain + Inosine/uridine-preferring nucleoside hydrolase Bcin11g01670 428 Bcin11g01680 574 Bcin11g01690 419 Aliphatic acid kinase, short-chain + Acetate/Proprionate kinase + Aliphatic acid kinase, short-chain, conserved site Bcin11g01700 831 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase + Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site + Thiamin diphosphate-binding fold Bcin11g01710 612 P-loop containing nucleoside triphosphate hydrolase Bcin11g01720 352 yes Cys2His2 transcription factor//Signaling pathway Bcltf3, Light-responsive Cys2His2 transcription factor Bcin11g01730 125 Effector(V2) Bcin11g01740 187 Effector(V2)|Effector(V1) Bcin11g01750 613 "Bcprp31, similar to yeast PRP31, Splicing factor; component of the U4/U6-U5 snRNP complex [Source:SGD;Acc:S000003323]" Bcin11g01760 682 "Bcclf1, similar to yeast CLF1, Member of the NineTeen Complex (NTC); this complex contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; homolog of Drosophila crooked neck protein; interacts with U1 snRNP proteins [Source:SGD;Acc:S000004107]" Bcin11g01770 493 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin11g01780 661 Protein kinase domain + Protein kinase-like domain + Protein kinase, ATP binding site + Calcium/calmodulin-dependent/calcium-dependent protein kinase Bcin11g01790 298 CSN8/PSMD8/EIF3K Bcin11g01800 311 AdipoR/Haemolysin-III-related Bcin11g01810 288 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin11g01820 225 Bcin11g01830 246 CAZy : GT2 //Effector(V2)|Effector(V1) "Bcdpm1, similar to yeast DPM1, Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane; catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation [Source:SGD;Acc:S000006387]" Bcin11g01840 611 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin11g01850 339 Bcin11g01860 194 Effector(V2)|Effector(V1) Thioesterase superfamily + HotDog domain Bcin11g01870 654 Bcin11g01880 180 Effector(V1) "Bcdap1, similar to yeast DAP1, Heme-binding protein; involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis [Source:SGD;Acc:S000006091]" Bcin11g01890 321 Bcin11g01900 260 Bcin11g01910 318 SignalP-noTM Bcin11g01920 890 "Bcvps35, similar to yeast VPS35, Endosomal subunit of membrane-associated retromer complex; required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval; interacts with Ypt7p [Source:SGD;Acc:S000003690]" Bcin11g01930 872 Protease Protease-associated domain, PA + Transferrin receptor-like, dimerisation domain + Peptidase M28 + Glutamate carboxypeptidase 2 homologue Bcin11g01940 445 Bcin11g01950 871 Bcin11g01960 216 Bcin11g01970 598 Protease Peptidase S54, rhomboid domain Bcin11g01980 3178 Protein of unknown function DUF3638 + Protein of unknown function DUF3645 Bcin11g01990 256 Bcin11g02000 504 Bcin11g02010 528 Transporter Amino acid/polyamine transporter I Bcin11g02020 249 Effector(V1) Acyl-CoA N-acyltransferase + GNAT domain Bcin11g02030 104 SignalP-TM Cardiolipin synthase N-terminal Bcin11g02040 498 "Bcuga2, similar to yeast UGA2, Succinate semialdehyde dehydrogenase; involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm [Source:SGD;Acc:S000000210]" Bcin11g02050 355 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin11g02060 528 Protein of unknown function DUF3445 Bcin11g02070 417 Bcin11g02080 123 Bcin11g02090 326 Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin11g02100 613 "Bcmus81, similar to yeast MUS81, Subunit of structure-specific Mms4p-Mus81p endonuclease; cleaves branched DNA; involved in DNA repair, replication fork stability, and joint molecule formation/resolution during meiotic recombination; promotes template switching during break-induced replication (BIR), causing non-reciprocal translocations (NRTs); helix-hairpin-helix protein; phosphorylation of non-catalytic subunit Mms4p by Cdc28p and Cdcp during mitotic cell cycle activates function of Mms4p-Mus81p [Source:SGD;Acc:S000002794]" Bcin11g02110 336 "Bchmt1, similar to yeast HMT1, Nuclear SAM-dependent mono- and asymmetric methyltransferase; modifies hnRNPs, including Npl3p and Hrp1p, affecting their activity and nuclear export; methylates U1 snRNP protein Snp1p and ribosomal protein Rps2p; interacts genetically with genes encoding components of Rpd3(L) and this interaction is important for Rpd3 recruitment to the subtelomeric region. [Source:SGD;Acc:S000000238]" Bcin11g02120 726 "Bcbrf1, similar to yeast BRF1, TFIIIB B-related factor; one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB [Source:SGD;Acc:S000003478]" Bcin11g02130 538 "Bcpcm1, similar to yeast PCM1, Essential N-acetylglucosamine-phosphate mutase; converts GlcNAc-6-P to GlcNAc-1-P, which is a precursor for the biosynthesis of chitin and for the formation of N-glycosylated mannoproteins and glycosylphosphatidylinositol anchors [Source:SGD;Acc:S000000784]" Bcin11g02140 222 Effector(V2)|Effector(V1) Bcin11g02150 250 SignalP-noTM Phosphatidylethanolamine-binding protein PEBP Bcin11g02160 1096 Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin11g02170 584 SignalP-noTM Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin11g02180 1010 CAZy : GH35PCW hemicellulose//SignalP-noTM Glycoside hydrolase, family 35 + Galactose-binding domain-like + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Beta-galactosidase, domain 2 + Glycoside hydrolase, family 35, conserved site + Beta-galactosidase jelly roll domain + Beta-galactosidase, domain 3 + Glycoside hydrolase 35, catalytic domain Bcin11g02190 656 Homeobox transcription factor Bchox3, Homeobox transcription factor Bcin11g02200 326 SignalP-noTM "Bcper1, similar to yeast PER1, Protein of the endoplasmic reticulum; required for GPI-phospholipase A2 activity that remodels the GPI anchor as a prerequisite for association of GPI-anchored proteins with lipid rafts; functionally complemented by human ortholog PERLD1 [Source:SGD;Acc:S000000640]" Bcin11g02210 313 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin11g02220 996 "Bcdis3, similar to yeast DIS3, Exosome core complex catalytic subunit; has both endonuclease and 3'-5' exonuclease activity; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; role in degradation of tRNAs; has similarity to E. coli RNase R and to human DIS3; mutations in Dis3p corresponding to human mutations implicated in multiple myeloma cause phenotypes suggesting impaired exosome function; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005381]" Bcin11g02230 661 "Bcswp82, similar to yeast SWP82, Member of the SWI/SNF chromatin remodeling complex; has an as yet unidentified role in the complex; has identifiable counterparts in closely related yeast species; abundantly expressed in many growth conditions; paralog of Npl6p; relocates to the cytosol under hypoxic conditions [Source:SGD;Acc:S000001845]" Bcin11g02240 239 Effector(V1) HAD hydrolase, subfamily IA + HAD-like domain + Phosphoglycolate phosphatase, domain 2 Bcin11g02250 530 "Bcnug1, similar to yeast NUG1, GTPase that associates with nuclear 60S pre-ribosomes; required for export of 60S ribosomal subunits from the nucleus [Source:SGD;Acc:S000000808]" Bcin11g02260 1181 Ankyrin repeat + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase + NWD NACHT-NTPase, N-terminal Bcin11g02270 799 Indoleamine 2,3-dioxygenase + Cytochrome b5-like heme/steroid binding domain + Cytochrome b5, heme-binding site Bcin11g02280 552 CAZy : GH5PCW/FCW Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin11g02290 375 Helix-loop-helix (HLH) transcription factor Myc-type, basic helix-loop-helix (bHLH) domain Bcin11g02300 260 Bcin11g02310 283 Vacuolar import/degradation protein Vid24 Bcin11g02320 154 Mago nashi protein Bcin11g02330 958 "Bcsec26, similar to yeast SEC26, Essential beta-coat protein of the COPI coatomer; involved in ER-to-Golgi protein trafficking and maintenance of normal ER morphology; shares 43% sequence identity with mammalian beta-coat protein (beta-COP) [Source:SGD;Acc:S000002646]" Bcin11g02340 521 Diacylglycerol kinase, catalytic domain + NAD kinase/diacylglycerol kinase-like domain Bcin11g02350 269 "Bcrrp1, similar to yeast RRP1, Essential evolutionarily conserved nucleolar protein; necessary for biogenesis of 60S ribosomal subunits and for processing of pre-rRNAs to mature rRNA; associated with several distinct 66S pre-ribosomal particles [Source:SGD;Acc:S000002494]" Bcin11g02360 317 yes BcDIM5, Deficient in Methylation Bcin11g02370 444 Bcin11g02380 525 Alcohol acetyltransferase Bcin11g02390 408 Bcin11g02400 264 Effector(V2)|Effector(V1) Bcin11g02410 978 Domain of unknown function DUF221 + Domain of unknown function DUF4463 + Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain Bcin11g02420 338 Bcin11g02430 420 Bcin11g02440 948 Ubiquitin system component Cue + UBA-like Bcin11g02450 1154 Ankyrin repeat + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin11g02460 186 Effector(V2)|Effector(V1) GroES (chaperonin 10)-like + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain Bcin11g02470 178 Effector(V2)|Effector(V1) Bcin11g02480 407 Heterokaryon incompatibility Bcin11g02490 554 Alpha-D-phosphohexomutase superfamily + Alpha-D-phosphohexomutase, C-terminal + Alpha-D-phosphohexomutase, alpha/beta/alpha domain I + Alpha-D-phosphohexomutase, alpha/beta/alpha domain II + Alpha-D-phosphohexomutase, alpha/beta/alpha domain III + Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III Bcin11g02500 193 "Bcrex2, similar to yeast REX2, 3'-5' RNA exonuclease; involved in 3'-end processing of U4 and U5 snRNAs, 5S and 5.8S rRNAs, and RNase P and RNase MRP RNA; localized to mitochondria and null suppresses escape of mtDNA to nucleus in yme1 yme2 mutants; RNase D exonuclease [Source:SGD;Acc:S000004049]" Bcin11g02510 395 Bcin11g02520 552 Bcin11g02530 175 Effector(V2)|Effector(V1) Bcin11g02540 173 Effector(V2)|Effector(V1) Bcin11g02550 90 Effector(V1) Bcin11g02560 736 Bcin11g02570 1662 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin11g02580 541 "Bctim44, similar to yeast TIM44, Essential component of the TIM23 complex; tethers the import motor and regulatory factors (PAM complex) to the translocation channel (Tim23p-Tim17p core complex); TIM23 complex is short for the translocase of the inner mitochondrial membrane [Source:SGD;Acc:S000001284]" Bcin11g02590 260 Ribosomal protein S11 Bcin11g02600 247 Protease PPPDE putative peptidase domain Bcin11g02610 395 Ribosome-binding ATPase YchF/Obg-like ATPase 1 + GTP binding domain + Beta-grasp domain + TGS-like + Domain of unknown function DUF933 + TGS-like domain + P-loop containing nucleoside triphosphate hydrolase + OBG-type guanine nucleotide-binding (G) domain Bcin11g02620 527 SM cluster PKS4-NRPS8 "Bchol1, similar to yeast HOL1, Putative transporter in the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; mutations in membrane-spanning domains permit cation and histidinol uptake [Source:SGD;Acc:S000005338]" Bcin11g02630 298 SM cluster PKS4-NRPS8 Phytanoyl-CoA dioxygenase Bcin11g02640 534 SM cluster PKS4-NRPS8 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin11g02650 1610 SM cluster PKS4-NRPS8 (KE) Bcnrps8, Nonribosomal peptide synthetase Bcin11g02660 281 S-adenosyl-L-methionine-dependent methyltransferase Bcin11g02670 264 SM cluster PKS4-NRPS8//Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin11g02680 552 SM cluster PKS4-NRPS8 AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain Bcin11g02690 261 SM cluster PKS4-NRPS8 Serine hydrolase FSH + Alpha/Beta hydrolase fold Bcin11g02700 2457 SM cluster PKS4-NRPS8 (KE) Bcpks4, Polyketide synthase Bcin11g02710 355 "Bcsgt2, similar to yeast SGT2, Glutamine-rich cytoplasmic cochaperone; serves as a scaffold bringing together Get4, Get5p, and other TRC complex members that are required to mediate posttranslational insertion of tail-anchored proteins into the ER membrane; interacts with the prion domain of Sup35p; amyloid sensor; plays a role in targeting chaperones to prion aggregates; has similarity to human cochaperone SGT; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000005533]" Bcin11g02720 323 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin11g02730 495 BcPIO5, Gene with a peak of expression during the Outset of colonization Bcin11g02740 807 Bcin11g02750 341 "Bcdus4, similar to yeast DUS4, Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus3p [Source:SGD;Acc:S000004397]" Bcin11g02760 118 Bcin11g02770 710 Leucine-rich repeat domain, L domain-like Bcin11g02780 333 Bcin11g02790 460 AdipoR/Haemolysin-III-related Bcin11g02800 535 Bcin11g02810 137 Effector(V2)|Effector(V1) Bcin11g02820 1163 Uncharacterised protein family UPF0592 Bcin11g02830 877 SignalP-noTM Carbohydrate-binding WSC Bcin11g02840 547 Cyclin, N-terminal + Cyclin-like Bcin11g02850 423 Bcin11g02860 355 Bcin11g02870 364 Bcin11g02880 237 Bcin11g02890 525 yes Transporter Bchnm1, choline transporter Bcin11g02900 291 Protease//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Peptidase S1 + Peptidase S1A, chymotrypsin-type + Trypsin-like cysteine/serine peptidase domain + Peptidase S1, trypsin family, active site + Serine proteases, trypsin family, serine active site Bcin11g02910 928 Bcin11g02920 469 Annexin + Annexin, type fungal XIV + Annexin repeat, conserved site + Annexin repeat Bcin11g02930 439 Bcin11g02940 69 Effector(V2)|Effector(V1) Translation machinery associated TMA7 Bcin11g02950 803 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin11g02960 463 Signaling pathway Bpk4, Ran1-like protein kinase Bcin11g02970 355 Bcin11g02980 335 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin11g02990 557 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin11g03000 510 Zinc finger, RING-CH-type + Zinc finger, RING/FYVE/PHD-type + E3 ubiquitin-protein ligase MARCH-like Bcin11g03010 530 CAZy : GT31 Protein of unknown function DUF604 + Copper type II, ascorbate-dependent monooxygenase-like, C-terminal Bcin11g03020 522 Galactokinase + GHMP kinase, ATP-binding, conserved site + GHMP kinase N-terminal domain + Mevalonate/galactokinase + GHMP kinase, C-terminal domain + Ribosomal protein S5 domain 2-type fold, subgroup + Galactokinase galactose-binding domain + Galactokinase, conserved site + Ribosomal protein S5 domain 2-type fold Bcin11g03030 485 Tetratricopeptide-like helical domain Bcin11g03040 699 TPP-binding enzyme, conserved site + Thiamine pyrophosphate enzyme, C-terminal TPP-binding + Thiamine pyrophosphate enzyme, central domain + Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain + Acetolactate synthase, large subunit, biosynthetic + DHS-like NAD/FAD-binding domain + Thiamin diphosphate-binding fold Bcin11g03050 1078 Transporter P-type ATPase + Cation-transporting P-type ATPase, N-terminal + Cation-transporting P-type ATPase, C-terminal + P-type ATPase, subfamily IID + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, transmembrane domain + P-type ATPase, cytoplasmic domain N Bcin11g03060 189 Effector(V1) Bcin11g03070 222 Effector(V2)|Effector(V1) Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin11g03080 405 Oxysterol-binding protein + Oxysterol-binding protein, conserved site Bcin11g03090 360 "Bcfba1, similar to yeast FBA1, Fructose 1,6-bisphosphate aldolase; required for glycolysis and gluconeogenesis; catalyzes conversion of fructose 1,6 bisphosphate to glyceraldehyde-3-P and dihydroxyacetone-P; locates to mitochondrial outer surface upon oxidative stress; N-terminally propionylated in vivo [Source:SGD;Acc:S000001543]" Bcin11g03100 281 Ribosomal protein L9 + Ribosomal protein L9/RNase H1, N-terminal + Ribosomal protein L9, C-terminal + Ribosomal protein L9, N-terminal Bcin11g03110 668 Protease "Bcubp16, similar to yeast UBP16, Deubiquitinating enzyme anchored to the outer mitochondrial membrane; probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria [Source:SGD;Acc:S000005993]" Bcin11g03120 798 Bcin11g03130 448 Brix domain Bcin11g03140 486 "Bcrrp3, similar to yeast RRP3, Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; homologous to eIF-4a, which is a DEAD box RNA-dependent ATPase with helicase activity [Source:SGD;Acc:S000001107]" Bcin11g03150 450 CoA-transferase family III + CoA-transferase family III domain Bcin11g03160 492 Zinc finger, PHD-type + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, PHD-type, conserved site + Zinc finger, PHD-finger Bcin11g03170 297 Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin11g03180 482 Bcin11g03190 1218 "Bcnst1, similar to yeast NST1, Protein of unknown function; mediates sensitivity to salt stress; interacts physically with the splicing factor Msl1p and also displays genetic interaction with MSL1 [Source:SGD;Acc:S000005035]" Bcin11g03200 200 Effector(V2)|Effector(V1) "Bcrho2, similar to yeast RHO2, Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; involved in the establishment of cell polarity and in microtubule assembly [Source:SGD;Acc:S000005034]" Bcin11g03210 178 Bcin11g03220 309 Protein of unknown function DUF1749 + Alpha/Beta hydrolase fold Bcin11g03230 603 Bcin11g03240 125 Effector(V1) Bcin11g03250 361 SignalP-noTM Bcin11g03260 82 Effector(V1) Bcpio9, Gene with a peak of expression during the Outset of colonization Bcin11g03270 200 Effector(V2)|Effector(V1) PUA domain + Uncharacterised domain CHP00451 + PUA-like domain + Translation-associated RNA-binding, predicted Bcin11g03280 127 Ribosomal protein L29 Bcin11g03290 729 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin11g03300 132 Effector(V1) Bcin11g03310 1179 "Bcprp5, similar to yeast PRP5, RNA helicase in the DEAD-box family; necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA [Source:SGD;Acc:S000000441]" Bcin11g03320 335 HMG (high mobility group) transcription factor High mobility group box domain Bcin11g03330 537 Transporter Amino acid transporter, transmembrane domain Bcin11g03340 54 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin11g03350 102 Effector(V2) Bcin11g03360 430 Bcin11g03370 606 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin11g03380 1452 SignalP-noTM Carbohydrate-binding WSC + PapD-like Bcin11g03390 1081 SNF2-related + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase + Helicase, C-terminal + Zinc finger, RING/FYVE/PHD-type Bcin11g03400 1050 Bcin11g03410 1008 Nuclear pore protein 84/107 Bcin11g03420 80 Effector(V2)|Effector(V1) "Bccmc4, similar to yeast CMC4, Protein that localizes to the mitochondrial intermembrane space; localizes via the Mia40p-Erv1p system; contains twin cysteine-x(9)-cysteine motifs [Source:SGD;Acc:S000028514]" Bcin11g03430 96 Early secretome "Bcsmt3, similar to yeast SMT3, Ubiquitin-like protein of the SUMO family; conjugated to lysine residues of target proteins; associates with transcriptionally active genes; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics; phosphorylated at Ser2 [Source:SGD;Acc:S000002918]" Bcin11g03440 187 Bcin11g03450 688 "Bclsc1, similar to yeast LSC1, Alpha subunit of succinyl-CoA ligase; succinyl-CoA ligase is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate; phosphorylated [Source:SGD;Acc:S000005668]" Bcin11g03460 381 SignalP-noTM Bcin11g03470 246 CBF/NF-Y/archaeal histone transcription factor Transcription factor CBF/NF-Y/archaeal histone + Histone-fold Bcin11g03480 335 Aminotransferases, class-I, pyridoxal-phosphate-binding site + Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase Bcin11g03490 291 Bcin11g03500 1158 Bcin11g03510 95 Bcin11g03520 395 S-adenosylmethionine synthetase + S-adenosylmethionine synthetase, N-terminal + S-adenosylmethionine synthetase, central domain + S-adenosylmethionine synthetase, C-terminal + S-adenosylmethionine synthetase, conserved site + S-adenosylmethionine synthetase superfamily Bcin11g03530 288 "Bcgpn3, similar to yeast GPN3, Putative GTPase with a role in biogenesis of RNA pol II and polIII; may be involved in assembly of RNA polymerases II and III and in their transport into the nucleus; may have a role in sister chromatid cohesion; contains a Gly-Pro-Asn motif in the G domain; similar to Npa3p and Gpn2p [Source:SGD;Acc:S000004233]" Bcin11g03540 167 Effector(V1) Bcin11g03550 944 DNA replication regulator Sld3 Bcin11g03560 1353 yes Signaling pathway Bos4, Mitogen-activated protein kinase (MAPK) : MAPKKK Bcin11g03570 477 Transporter General substrate transporter + Major facilitator superfamily domain Bcin11g03580 480 Ammonium transporter + Ammonium transporter, conserved site + Ammonium transporter AmtB-like domain + Ammonium/urea transporter Bcin11g03590 578 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin11g03600 163 Effector(V2)|Effector(V1) Acyl-CoA N-acyltransferase Bcin11g03610 605 Asparagine synthase + Rossmann-like alpha/beta/alpha sandwich fold + Glutamine amidotransferase type 2 domain + Nucleophile aminohydrolases, N-terminal Bcin11g03620 807 VPS9 domain + Ubiquitin system component Cue + UBA-like Bcin11g03630 815 Bcin11g03640 266 HAD-like domain Bcin11g03650 808 Zn2/Cys6 + fungal trans transcription factor//Effector(V1) Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin11g03660 660 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin11g03670 1016 Bcin11g03680 901 Bcin11g03690 266 GNAT domain + Acyl-CoA N-acyltransferase Bcin11g03700 819 "Bcpol4, similar to yeast POL4, DNA polymerase IV; undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta [Source:SGD;Acc:S000000607]" Bcin11g03710 529 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin11g03720 600 TRAPP II complex, Trs65 Bcin11g03730 790 "Bcprp40, similar to yeast PRP40, U1 snRNP protein involved in splicing; interacts with the branchpoint-binding protein during the formation of the second commitment complex [Source:SGD;Acc:S000001495]" Bcin11g03740 609 "Bcrli1, similar to yeast RLI1, Essential Fe-S protein; required for ribosome biogenesis, translation initiation/termination; facilitates binding of multifactor complex (MFC) of initiation factors to small ribosomal subunit; Dom34-Hbs1 complex and Rli1p work in dissociating inactive ribosomes, thereby facilitating translation restart; forms complex with Lto1p and Yae1p; dependency on ROS-labile FeS clusters, activity in nuclear ribosomal-subunit export impaired by mild oxidative stress [Source:SGD;Acc:S000002498]" Bcin11g03750 1531 "Bcchd1, similar to yeast CHD1, Chromatin remodeler that regulates various aspects of transcription; acts in in conjunction with Isw1b to regulate chromatin structure and maintain chromatin integrity during transcription elongation by RNAP II by preventing trans-histone exchange over coding regions; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SLIK complexes [Source:SGD;Acc:S000000966]" Bcin11g03760 561 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin11g03770 330 Fungal trans transcription factor Transcription factor domain, fungi Bcin11g03790 254 Bcin11g03800 327 MADS box transcription factor Transcription factor, MADS-box Bcin11g03810 646 "Bchst4, similar to yeast HST4, Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism [Source:SGD;Acc:S000002599]" Bcin11g03820 1031 Mediator complex, subunit Med16 Bcin11g03830 640 Bcgst17, Glutathione S-transferase Bcin11g03840 651 FAD-binding 8 + Ferric reductase, NAD binding + Ferric reductase transmembrane component-like domain + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel Bcin11g03850 746 "Bcnpr3, similar to yeast NPR3, Subunit of SEA (Seh1-associated), Npr2/3, and Iml1p complexes; Npr2/3 complex mediates downregulation of TORC1 activity upon amino acid limitation; SEA complex is a coatomer-related complex that associates dynamically with the vacuole; Iml1p complex (Iml1p-Npr2p-Npr3p) is required for non-nitrogen-starvation (NNS)-induced autophagy; required for Npr2p phosphorylation and Iml1p-Npr2p interaction; null mutant shows delayed meiotic DNA replication and double-strand break repair [Source:SGD;Acc:S000001015]" Bcin11g03860 768 Bcin11g03870 202 Bcin11g03880 163 Effector(V2)|Effector(V1) Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin11g03890 112 Effector(V2)|Effector(V1) "Bccox19, similar to yeast COX19, Protein required for cytochrome c oxidase assembly; located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs [Source:SGD;Acc:S000007245]" Bcin11g03900 239 Bcin11g03910 500 Impact, N-terminal + Ribosomal protein S5 domain 2-type fold + Uncharacterised protein family UPF0029, Impact, conserved site + Impact family Bcin11g03920 393 Adipose-regulatory protein, Seipin Bcin11g03930 277 SignalP-noTM Bcprd3, Peroxidase Bcin11g03940 2190 "Bccdc39, similar to yeast CDC39, Component of the CCR4-NOT1 core complex; this complex has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor [Source:SGD;Acc:S000000689]" Bcin11g03950 1111 "Bchof1, similar to yeast HOF1, SH3 domain-containing protein required for cytokinesis; localized to bud neck; phosphorylated by Dbf2p; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p [Source:SGD;Acc:S000004635]" Bcin11g03960 579 Bcin11g03970 124 Effector(V2)|Effector(V1) "Bcntf2, similar to yeast NTF2, Nuclear envelope protein; interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport [Source:SGD;Acc:S000000811]" Bcin11g03980 148 "Bctvp18, similar to yeast TVP18, Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments [Source:SGD;Acc:S000004675]" Bcin11g03990 1042 Altered inheritance of mitochondria protein 21 Bcin11g04000 562 CAZy : GH65Energy //SignalP-TM Glycoside hydrolase, family 65, central catalytic + Glycoside hydrolase, family 65, N-terminal + Six-hairpin glycosidase-like + Galactose mutarotase-like domain + Six-hairpin glycosidase Bcin11g04010 894 "Bcmcm10, similar to yeast MCM10, Essential chromatin-associated protein; involved in the initiation of DNA replication; required for the association of the MCM2-7 complex with replication origins; required to stabilize the catalytic subunit of DNA polymerase-alpha [Source:SGD;Acc:S000001412]" Bcin11g04020 461 Ribonuclease H2, subunit B Bcin11g04030 237 Effector(V1) DASH complex subunit Duo1 Bcin11g04040 471 Bcin11g04050 769 Survival protein SurE-like phosphatase/nucleotidase + Tubulin-tyrosine ligase/Tubulin polyglutamylase + ATP-grasp fold, subdomain 2 + Probable tubulin-tyrosine ligase Bcin11g04060 133 Effector(V1) Bcin11g04070 1451 Transporter P-type ATPase + Cation-transporting P-type ATPase, N-terminal + Cation-transporting P-type ATPase, C-terminal + P-type ATPase, subfamily IIB + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, transmembrane domain + P-type ATPase, cytoplasmic domain N Bcin11g04080 540 Sirtuin family + Sirtuin family, catalytic core domain + Sirtuin family, catalytic core small domain + DHS-like NAD/FAD-binding domain Bcin11g04090 1190 Domain of unknown function DUF2422 + Brefeldin A-sensitivity protein 4 Bcin11g04100 262 S-adenosyl-L-methionine-dependent methyltransferase Bcin11g04110 524 Permease, cytosine/purines, uracil, thiamine, allantoin + Purine-cytosine permease Bcin11g04120 746 SignalP-noTM "Bcppn1, similar to yeast PPN1, Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer; relocalizes from vacuole to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000002860]" Bcin11g04130 248 HD domain + Cyanamide hydratase, HD-type Bcin11g04140 437 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin11g04150 763 "Bcerb1, similar to yeast ERB1, Constituent of 66S pre-ribosomal particles; forms a complex with Nop7p and Ytm1p that is required for maturation of the large ribosomal subunit; required for maturation of the 25S and 5.8S ribosomal RNAs; homologous to mammalian Bop1 [Source:SGD;Acc:S000004652]" Bcin11g04160 224 Effector(V1) Bcin11g04170 560 Protein kinase domain + Protein kinase-like domain + Prion-inhibition and propagation, HeLo domain Bcin11g04180 305 "Bcerv29, similar to yeast ERV29, Protein localized to COPII-coated vesicles; involved in vesicle formation and incorporation of specific secretory cargo; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003516]" Bcin11g04190 442 WH2 domain Bcin11g04200 416 Bcin11g04210 319 Effector(V1) Cysteine/histidine-rich domain + CS domain + HSP20-like chaperone Bcin11g04220 109 Bcgrx5, Glutaredoxin-like Bcin11g04230 312 Effector(V2) HpcH/HpaI aldolase/citrate lyase domain + Pyruvate/Phosphoenolpyruvate kinase-like domain Bcin11g04240 227 Effector(V2)|Effector(V1) Carbohydrate kinase, thermoresistant glucokinase + P-loop containing nucleoside triphosphate hydrolase + Shikimate kinase/gluconokinase Bcin11g04250 480 Biotin/lipoyl attachment + 2-oxoacid dehydrogenase acyltransferase, catalytic domain + E3-binding domain + Single hybrid motif + Lipoamide Acyltransferase + Chloramphenicol acetyltransferase-like domain Bcin11g04260 348 "Bcatp10, similar to yeast ATP10, Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase; mitochondrial inner membrane protein; interacts genetically with ATP6 [Source:SGD;Acc:S000004385]" Bcin11g04270 227 Effector(V1) "Bcgos1, similar to yeast GOS1, v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28 [Source:SGD;Acc:S000001023]" Bcin11g04280 368 MOB kinase activator family Bcin11g04290 437 Leo1-like protein Bcin11g04300 570 Patatin/Phospholipase A2-related + Acyl transferase/acyl hydrolase/lysophospholipase + Triacylglycerol lipase Bcin11g04310 793 SWAP/Surp + CID domain Bcin11g04320 448 Bcdao2, D-amino acid oxidase 2 Bcin11g04330 251 Effector(V2)|Effector(V1) "Bcspt15, similar to yeast SPT15, TATA-binding protein; general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability [Source:SGD;Acc:S000000950]" Bcin11g04340 224 HMG (high mobility group) transcription factor//Effector(V1) High mobility group box domain Bcin11g04350 860 Zinc finger, LIM-type Bcin11g04360 512 Major facilitator superfamily + Major facilitator superfamily domain Bcin11g04370 425 Protein kinase-like domain Bcin11g04380 390 Bzip transcription factor Protein of unknown function DUF3425 Bcin11g04390 559 Bcin11g04400 192 Effector(V2)|Effector(V1) GNAT domain + Acyl-CoA N-acyltransferase Bcin11g04410 793 "Bchsp78, similar to yeast HSP78, Oligomeric mitochondrial matrix chaperone; cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; able to prevent the aggregation of misfolded proteins as well as resolubilize protein aggregates [Source:SGD;Acc:S000002666]" Bcin11g04420 230 Effector(V2) "Bcefb1, similar to yeast EFB1, Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site [Source:SGD;Acc:S000000003]" Bcin11g04430 147 SignalP-TM//Effector(V2)|Effector(V1) Magnesium transporter Bcin11g04440 985 "Bcmsh5, similar to yeast MSH5, Protein of the MutS family; forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans [Source:SGD;Acc:S000002313]" Bcin11g04450 200 SignalP-noTM Bcin11g04460 1561 yes Transporter BcatrA, ABC transporter Bcin11g04470 293 Ubiquitin-like + Ubiquitin-related domain + Ubiquitin-binding domain Bcin11g04480 78 Effector(V2)|Effector(V1) "Bcrpc10, similar to yeast RPC10, RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III; relocalizes from nucleolus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000001185]" Bcin11g04490 408 "Bcnpa3, similar to yeast NPA3, Member of the conserved GPN-loop GTPase family; has a role in transport of RNA polymerase II to the nucleus; exhibits GTP-dependent binding to PolII; has ATPase activity; involved in sister chromatid cohesion; phosphorylated by the Pcl1p-Pho85p kinase complex; human homolog XAB1 interacts with human RNA polymerase II; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003833]" Bcin11g04500 673 Cwf19-like protein, C-terminal domain-2 + Cwf19-like, C-terminal domain-1 + HIT-like domain Bcin11g04510 589 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin11g04520 712 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin11g04530 518 Ergosterol biosynthesis ERG4/ERG24 + Sterol reductase, conserved site Bcin11g04540 247 Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin11g04550 209 Effector(V2)|Effector(V1) Polyketide synthase, ketoreductase domain + NAD(P)-binding domain Bcin11g04570 430 Bcin11g04580 323 Bcin11g04590 855 Protein of unknown function DUF3405 Bcin11g04600 622 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin11g04610 212 SignalP-noTM//Effector(V2)|Effector(V1) "Bcemp24, similar to yeast EMP24, Component of the p24 complex; role in misfolded protein quality control; binds to GPI anchor proteins and mediates their efficient transport from the ER to the Golgi; integral membrane protein that associates with endoplasmic reticulum-derived COPII-coated vesicles [Source:SGD;Acc:S000003168]" Bcin11g04620 183 Effector(V1) Small GTP-binding protein domain + Small GTPase superfamily, ARF/SAR type + Small GTPase superfamily, ARF type + P-loop containing nucleoside triphosphate hydrolase Bcin11g04630 389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + NAD(P)-binding domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Bcin11g04640 412 "Bctrp4, similar to yeast TRP4, Anthranilate phosphoribosyl transferase; transferase of the tryptophan biosynthetic pathway; catalyzes the phosphoribosylation of anthranilate; subject to the general control system of amino acid biosynthesis [Source:SGD;Acc:S000002762]" Bcin11g04650 345 Bcin11g04660 488 Phospholipase C, phosphatidylinositol-specific , X domain + PLC-like phosphodiesterase, TIM beta/alpha-barrel domain Bcin11g04670 197 Effector(V2)|Effector(V1) Bcin11g04680 380 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin11g04690 214 Effector(V2)|Effector(V1) "Bcerg2, similar to yeast ERG2, C-8 sterol isomerase; catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis [Source:SGD;Acc:S000004815]" Bcin11g04700 239 NEFA-interacting nuclear protein NIP30, N-terminal Bcin11g04710 298 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin11g04720 168 Effector(V2)|Effector(V1) Histidine triad (HIT) protein + HIT-like domain + Histidine triad, conserved site Bcin11g04730 249 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Cysteine-rich secretory protein, allergen V5/Tpx-1-related + CAP domain + Allergen V5/Tpx-1-related, conserved site Bcin11g04740 856 "Bctrl1, similar to yeast TRL1, tRNA ligase; required for tRNA splicing and for both splicing and translation of HAC1 mRNA in the UPR; has phosphodiesterase, polynucleotide kinase, and ligase activities; localized at the inner nuclear envelope and partially to polysomes [Source:SGD;Acc:S000003623]" Bcin11g04750 220 Ankyrin repeat-containing domain Bcin11g04760 354 Ribonuclease P, Rpp40 Bcin11g04770 446 "Bctrm11, similar to yeast TRM11, Catalytic subunit of adoMet-dependent tRNA methyltransferase complex; required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain; another complex member is Trm112p [Source:SGD;Acc:S000005484]" Bcin11g04780 229 SignalP-noTM Bcin11g04790 339 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin11g04800 465 CAZy : CBM18,CBM18,CBM18,CE4FCW //SignalP-noTM Bccda2, chitin deacetylase Bcin11g04810 270 "Bcckb2, similar to yeast CKB2, Beta' regulatory subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase [Source:SGD;Acc:S000005565]" Bcin11g04820 607 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin11g04830 480 Cyclin, C-terminal domain + Cyclin, N-terminal + Cyclin-like Bcin11g04840 378 "Bcrml2, similar to yeast RML2, Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor [Source:SGD;Acc:S000000776]" Bcin11g04850 867 Zn2/Cys6 + fungal trans transcription factor Bcprf, Zn2/Cys6 transcription factor Bcin11g04860 332 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin11g04870 1088 Ribosome control protein 1 + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin11g04880 479 "Bcvma13, similar to yeast VMA13, Subunit H of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits [Source:SGD;Acc:S000006240]" Bcin11g04890 475 Glycine cleavage T-protein-like, N-terminal + Glycine cleavage system T protein + Glycine cleavage T-protein, C-terminal barrel domain + GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 + Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA + Glycine cleavage T-protein/YgfZ, C-terminal domain Bcin11g04900 470 Transporter Amino acid transporter, transmembrane domain Bcin11g04910 178 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin11g04920 203 Bcin11g04930 576 SignalP-noTM "Bcmsc1, similar to yeast MSC1, Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated [Source:SGD;Acc:S000004597]" Bcin11g04940 874 Kelch-type beta propeller Bcin11g04950 225 Bcin11g04960 279 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin11g04970 300 Protease Alpha/beta hydrolase fold-1 + Epoxide hydrolase-like + Alpha/Beta hydrolase fold Bcin11g04980 748 Heterokaryon incompatibility Bcin11g04990 504 CAZy : GT1 UDP-glucuronosyl/UDP-glucosyltransferase Bcin11g05000 310 MHCK/EF2 kinase + Protein kinase-like domain Bcin11g05010 429 Phosphatidic acid phosphatase type 2/haloperoxidase Bcin11g05020 257 SM 0 Protein of unknown function DUF3328 Bcin11g05030 240 Bcin11g05040 110 Effector(V1) Bcin11g05050 277 SUZ domain Bcin11g05060 572 "Bcnar1, similar to yeast NAR1, Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery; required for maturation of cytosolic and nuclear FeS proteins and for normal resistance to oxidative stress; deficiency results in shortened lifespan and sensitivity to paraquat; homologous to human Narf [Source:SGD;Acc:S000005184]" Bcin11g05070 184 Bcin11g05080 348 NADP-dependent oxidoreductase domain Bcin11g05090 395 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin11g05100 414 Zinc finger, CCCH-type Bcin11g05110 631 "Bcpac2, similar to yeast PAC2, Microtubule effector required for tubulin heterodimer formation; binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl [Source:SGD;Acc:S000000809]" Bcin11g05120 239 Effector(V1) "Bcprp11, similar to yeast PRP11, Subunit of the SF3a splicing factor complex; required for spliceosome assembly [Source:SGD;Acc:S000002201]" Bcin11g05130 663 "Bccbk1, similar to yeast CBK1, Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005105]" Bcin11g05140 238 Centromere protein H Bcin11g05150 1378 "Bcatg11, similar to yeast ATG11, Adapter protein for pexophagy and the Cvt targeting pathway; directs receptor-bound cargo to the phagophore assembly site (PAS) for packaging into vesicles; required for recruiting other proteins to the PAS; recruits Dnm1p to facilitate fission of mitochondria that are destined for removal by mitophagy [Source:SGD;Acc:S000006253]" Bcin11g05160 449 "Bcsah1, similar to yeast SAH1, S-adenosyl-L-homocysteine hydrolase; catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor; regulates cellular lipid homoeostasis by regulating phosphatidylcholine(PC)synthesis and triacylglycerol (TG) levels [Source:SGD;Acc:S000000845]" Bcin11g05170 367 Protease JAB1/MPN/MOV34 metalloenzyme domain + Eukaryotic translation initiation factor 3 subunit H Bcin11g05180 306 Dimeric alpha-beta barrel Bcin11g05190 329 Transporter Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin11g05200 195 Effector(V1) Uncharacterised conserved protein UCP022603 + Caffeine-induced death protein 2 Bcin11g05210 733 "Bcnat1, similar to yeast NAT1, Subunit of protein N-terminal acetyltransferase NatA; NatA is comprised of Nat1p, Ard1p, and Nat5p; N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing [Source:SGD;Acc:S000002198]" Bcin11g05220 819 Zinc finger, PHD-type + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, PHD-type, conserved site + Zinc finger, PHD-finger Bcin11g05230 480 "Bctim54, similar to yeast TIM54, Component of the mitochondrial TIM22 complex; involved in insertion of polytopic proteins into the inner membrane [Source:SGD;Acc:S000003590]" Bcin11g05240 101 HMG (high mobility group) transcription factor High mobility group box domain Bcin11g05250 505 Bcin11g05260 244 Bcin11g05270 330 Bcin11g05280 235 Cys2His2 transcription factor Zinc finger, U1-type + Zinc finger, C2H2 + Zinc finger, double-stranded RNA binding Bcin11g05290 291 Effector(V1) "Bcdph5, similar to yeast DPH5, Methyltransferase required for synthesis of diphthamide; diphthamide is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm [Source:SGD;Acc:S000004162]" Bcin11g05300 555 Bcin11g05310 659 Bcin11g05320 387 Bcin11g05330 112 Major facilitator superfamily + Major facilitator superfamily domain Bcin11g05340 775 Fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin11g05350 490 yes BcmctA, Monocarboxylate transcporter A Bcin11g05360 250 CAZy : AA9 //SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Glycoside hydrolase, family 61 Bcin11g05370 359 Bcin11g05380 101 Bcin11g05390 394 Eisosome component PIL1/LSP1 Bcin11g05400 292 Methyltransferase type 11 + S-adenosyl-L-methionine-dependent methyltransferase Bcin11g05410 395 Aerolysin-like toxin, beta complex domain Bcin11g05420 501 Bcin11g05430 505 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin11g05440 951 Bcin11g05450 259 Effector(V1) Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin11g05460 124 yes SignalP-noTM Bcin11g05470 390 Bcin11g05480 319 Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin11g05490 570 Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin11g05500 566 DnaJ domain Bcin11g05510 533 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin11g05520 495 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin11g05530 1256 "Bcrev1, similar to yeast REV1, Deoxycytidyl transferase; involved in repair of abasic sites and adducted guanines in damaged DNA by translesion synthesis (TLS); forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; relocalizes from nucleus to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000005873]" Bcin11g05540 180 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Carbohydrate-binding WSC Bcin11g05550 528 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin11g05560 785 Protease Peptidase M3A/M3B + Neurolysin/Thimet oligopeptidase, domain 2 + Metallopeptidase, catalytic domain + Mitochondrial intermediate peptidase Bcin11g05570 247 Effector(V1) "Bcmic26, similar to yeast MIC26, Component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; Mic26p is a non-essential component of the complex [Source:SGD;Acc:S000003467]" Bcin11g05580 415 "Bctys1, similar to yeast TYS1, Cytoplasmic tyrosyl-tRNA synthetase; required for cytoplasmic protein synthesis; interacts with positions 34 and 35 of the tRNATyr anticodon; mutations in human ortholog YARS are associated with Charcot-Marie-Tooth (CMT) neuropathies; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003417]" Bcin11g05590 274 Bcin11g05600 191 Bcin11g05610 282 Protease//Effector(V2) "Bcpre2, similar to yeast PRE2, Beta 5 subunit of the 20S proteasome; responsible for the chymotryptic activity of the proteasome [Source:SGD;Acc:S000006307]" Bcin11g05620 1198 Signal transduction response regulator, receiver domain + GAF domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily + GAF domain-like Bcin11g05630 246 Bcin11g05640 176 Effector(V2)|Effector(V1) Bcin11g05650 463 "Bcsua5, similar to yeast SUA5, Protein involved in threonylcarbamoyl adenosine biosynthesis; Sua5p and Qri7p are necessary and sufficient for RNA t6A modification in vitro; null mutant lacks N6-threonylcarbamoyl adenosine (t6A) modification in the anticodon loop of ANN-decoding tRNA; member of conserved YrdC/Sua5 family; binds single-stranded telomeric DNA and null mutant has abnormal telomere length [Source:SGD;Acc:S000003137]" Bcin11g05660 194 Effector(V1) "Bcret3, similar to yeast RET3, Zeta subunit of the coatomer complex (COPI); COPI coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER [Source:SGD;Acc:S000005931]" Bcin11g05670 470 Bcin11g05680 403 "Bcrmt2, similar to yeast RMT2, Arginine N5 methyltransferase; methylates ribosomal protein Rpl12 (L12) on Arg67; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000002873]" Bcin11g05690 503 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin11g05700 491 yes Bchxk, Hexokinase Bcin11g05710 495 SignalP-noTM "Bcost1, similar to yeast OST1, Alpha subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes asparagine-linked glycosylation of newly synthesized proteins [Source:SGD;Acc:S000003539]" Bcin11g05720 628 Heterokaryon incompatibility Bcin11g05730 818 "Bcvtc4, similar to yeast VTC4, Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) complex involved in synthesis and transfer of polyP to the vacuole; regulates membrane trafficking; role in non-autophagic vacuolar fusion; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003549]" Bcin11g05740 456 Protease Amidohydrolase 1 + Guanine deaminase + Metal-dependent hydrolase Bcin11g05750 239 SGNH hydrolase-type esterase domain Bcin11g05760 1025 "Bcmcm4, similar to yeast MCM4, Essential helicase component of heterohexameric MCM2-7 complexes; MCM2-7 complexes bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p [Source:SGD;Acc:S000006223]" Bcin11g05770 1107 Cyclic nucleotide-binding domain + Sulphate anion transporter + STAS domain + Sulphate transporter + RmlC-like jelly roll fold + Cyclic nucleotide-binding-like Bcin11g05780 218 Effector(V1) "Bcpsf1, similar to yeast PSF1, Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p); complex is localized to DNA replication origins and implicated in assembly of the DNA replication machinery [Source:SGD;Acc:S000002420]" Bcin11g05790 538 HMG (high mobility group) transcription factor//Signaling pathway High mobility group box domain Bcin11g05800 243 SM 0//Effector(V2)|Effector(V1) Protein of unknown function DUF3328 Bcin11g05810 2161 yes Signaling pathway Bccch1, Ca2 channel protein Bcin11g05820 608 Bcin11g05830 691 Ferroporti-1 + Major facilitator superfamily domain Bcin11g05840 90 Bcin11g05850 115 Bcin11g05860 205 Effector(V2)|Effector(V1) Cytochrome P450 Bcin11g05870 596 GATA zinc finger transcription factor Bcsnf5, GATA zinc finger transcription factor Bcin11g05880 577 Bcin11g05890 386 26S proteasome complex ubiquitin receptor, subunit Rpn13 Bcin11g05900 200 60S ribosomal protein L6E + Translation protein SH3-like domain + Ribosomal protein L2 domain 2 Bcin11g05910 764 Protease Dipeptidyl-peptidase 3 Bcin11g05920 191 Effector(V2)|Effector(V1) Ribosomal protein L6 + Ribosomal protein L6, conserved site-2 + Ribosomal protein L6, alpha-beta domain Bcin11g05930 394 SignalP-noTM Bcin11g05940 589 Transporter Multidrug resistance protein + Major facilitator superfamily + Major facilitator superfamily domain Bcin11g05950 271 Bcgrx2, Glutaredoxin Bcin11g05960 902 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin11g05970 336 Fatty acid hydroxylase Bcin11g05980 332 Bcin11g05990 142 Bcin11g06000 351 Effector(V2) MaoC-like domain + HotDog domain Bcin11g06010 350 "Bcsua7, similar to yeast SUA7, Transcription factor TFIIB; a general transcription factor required for transcription initiation and start site selection by RNA polymerase II [Source:SGD;Acc:S000006290]" Bcin11g06020 461 "Bcrpt5, similar to yeast RPT5, ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription; similar to human TBP1 [Source:SGD;Acc:S000005643]" Bcin11g06030 238 Effector(V2)|Effector(V1) BTB/POZ-like + BTB/POZ fold Bcin11g06040 324 Polysaccharide deacetylase Bcin11g06050 1306 Phox homologous domain + Ankyrin repeat + VPS9 domain + Ankyrin repeat-containing domain Bcin11g06060 533 Oxidoreductase, N-terminal + Oxidoreductase, C-terminal + NAD(P)-binding domain Bcin11g06070 264 Bcin11g06080 122 Effector(V1) ATPase, F0 complex, subunit H Bcin11g06090 326 SignalP-noTM Bcin11g06100 518 "Bcnpl6, similar to yeast NPL6, Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions; involved in nuclear protein import and maintenance of proper telomere length [Source:SGD;Acc:S000004697]" Bcin11g06110 914 yes Signaling pathway BPK2, Sch9-like cAMP-dependent protein kinase catalytic subunit Bcin11g06120 599 SignalP-noTM FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin11g06130 335 "Bcclg1, similar to yeast CLG1, Cyclin-like protein that interacts with Pho85p; has sequence similarity to G1 cyclins PCL1 and PCL2 [Source:SGD;Acc:S000003183]" Bcin11g06140 696 Tetratricopeptide-like helical domain + Chs5p-Arf1p binding Bcin11g06150 337 Bcin11g06160 943 Protease Amidohydrolase 1 + Metal-dependent hydrolase, composite domain + Metal-dependent hydrolase Bcin11g06170 1836 "Bchir3, similar to yeast HIR3, Subunit of the HIR complex; a nucleosome assembly complex involved in regulation of histone gene transcription; involved in position-dependent gene silencing and nucleosome reassembly; ortholog of human CABIN1 protein [Source:SGD;Acc:S000003901]" Bcin11g06180 544 Permease, cytosine/purines, uracil, thiamine, allantoin + Purine-cytosine permease Bcin11g06190 335 Bcin11g06200 410 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin11g06210 134 Effector(V2)|Effector(V1) Bcin11g06220 195 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin11g06230 275 Mpv17/PMP22 Bcin11g06240 418 "Bcpgk1, similar to yeast PGK1, 3-phosphoglycerate kinase; catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis [Source:SGD;Acc:S000000605]" Bcin11g06250 94 DSS1/SEM1 Bcin11g06260 691 Outer membrane protein Iml2/Tetratricopeptide repeat protein 39 Bcin11g06270 603 Delta-1-pyrroline-5-carboxylate dehydrogenase + Aldehyde dehydrogenase domain + Aldehyde dehydrogenase, cysteine active site + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain + Aldehyde dehydrogenase, C-terminal + Aldehyde dehydrogenase, glutamic acid active site Bcin11g06280 467 Major facilitator superfamily + Major facilitator superfamily domain Bcin11g06290 274 BTB/POZ-like + BTB/POZ fold Bcin11g06300 539 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin11g06310 301 NmrA-like domain + NAD(P)-binding domain Bcin11g06320 849 Kinesin motor domain + Kinesin motor domain, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin11g06330 871 Rab-GTPase-TBC domain Bcin11g06340 153 Effector(V2)|Effector(V1) Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like Bcin11g06350 172 Protease//Effector(V1) "Bcsec11, similar to yeast SEC11, 18kDa catalytic subunit of the Signal Peptidase Complex (SPC); the Signal Peptidase Complex cleaves the signal sequence of proteins targeted to the endoplasmic reticulum; other members are Spc1p, Spc2p, Spc3p, and Sec11p [Source:SGD;Acc:S000001461]" Bcin11g06360 292 Bcin11g06370 533 Bcin11g06380 140 Effector(V1) Bcin11g06390 247 Bcin11g06400 160 SignalP-noTM Bcin11g06410 209 Effector(V1) Bcin11g06420 1730 Cys2His2 transcription factor SANT/Myb domain + Zinc finger, C2H2 + Homeodomain-like + Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Zinc finger, C2H2-like + Myb-like domain + Tetratricopeptide repeat Bcin11g06430 425 SignalP-noTM DOMON domain + Cytochrome b561/ferric reductase transmembrane + Cellobiose dehydrogenase, cytochrome domain + Domain of unknown function DUF2427 Bcin11g06440 997 CAZy : GH31PCW hemicellulose//SignalP-noTM//Early secretome Glycoside hydrolase family 31 + Galactose mutarotase-like domain + Glycoside hydrolase superfamily + Glycosyl hydrolases family 31, active site + Glycosyl hydrolases family 31, conserved site + Galactose mutarotase, N-terminal barrel Bcin11g06450 714 yes SignalP-noTM//Early secretome Bccat2, Catalase Bcin11g06460 355 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain Bcin11g06470 298 Beta-lactamase-like Bcin11g06480 508 Protein kinase domain + AGC-kinase, C-terminal + Serine/threonine-protein kinase, active site + Protein kinase-like domain Bcin11g06490 301 Bcin11g06500 302 Bcin11g06510 321 yes BcSTC7, sesquiterpen cyclase Bcin11g06520 519 Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin11g06530 569 Bcin11g06540 452 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin11g06550 205 Effector(V2)|Effector(V1) NmrA-like domain + NAD(P)-binding domain + Ankyrin repeat-containing domain Bcin11g06560 1386 Bcin12g00010 489 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin12g00020 98 Effector(V1) Bcin12g00030 318 NmrA-like domain + NAD(P)-binding domain Bcin12g00040 550 Amidase + Amidase, conserved site + Amidase signature domain Bcin12g00050 587 SignalP-noTM Alpha-L-rhamnosidase RhaM Bcin12g00060 600 SET domain Bcin12g00070 601 Bicarbonate transporter, eukaryotic + Bicarbonate transporter, C-terminal Bcin12g00080 81 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2) Bcin12g00090 281 CAZy : GH11PCW hemicellulose//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa BcXyn11C, Xylanase of family GH11 (Garcia et al., 2017) Bcin12g00100 168 Effector(V1) Bcin12g00110 99 Effector(V2)|Effector(V1) Bcin12g00120 249 Signaling pathway "Bcbos1, similar to yeast BOS1, v-SNARE (vesicle specific SNAP receptor); localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi [Source:SGD;Acc:S000004068]" Bcin12g00130 140 Effector(V1) Bcin12g00140 551 Carbon-nitrogen hydrolase Bcin12g00150 376 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin12g00160 229 Effector(V2)|Effector(V1) NAD(P)-binding domain Bcin12g00170 829 Conserved hypothetical protein CHP02231 + Domain of unknown function DUF4140 Bcin12g00180 432 Protease//SignalP-noTM Bcap9, Aspartic proteinase Bcin12g00190 543 Protease "Bcgua1, similar to yeast GUA1, GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA [Source:SGD;Acc:S000004830]" Bcin12g00200 299 "Bcthi80, similar to yeast THI80, Thiamine pyrophosphokinase; phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate) [Source:SGD;Acc:S000005669]" Bcin12g00210 318 "Bcmia40, similar to yeast MIA40, Mitochondrial oxidoreductase; involved in mitochondrial intermembrane space import; component of MIA pathway which mediates import and oxidative folding of substrates including small proteins containing twin cysteine motifs; acts in concert with Erv1p, which oxidizes the cysteine residues of Mia40p to comprise a disulfide relay system that catalyzes import; also mediates folding of Atp23p via a chaperone-like activity; forms a dimer that binds iron-sulfur cluster in vitro [Source:SGD;Acc:S000001678]" Bcin12g00220 188 Effector(V2)|Effector(V1) Bcin12g00230 279 BTB/POZ-like + BTB/POZ fold Bcin12g00240 218 Bcin12g00250 268 Bcin12g00260 630 Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g00270 238 GNAT domain + Acyl-CoA N-acyltransferase Bcin12g00280 263 Pyridoxal phosphate phosphatase-related + HAD-like domain Bcin12g00290 466 "Bcshe9, similar to yeast SHE9, Protein required for normal mitochondrial morphology; mitochondrial inner membrane protein; may be involved in fission of the inner membrane; forms a homo-oligomeric complex [Source:SGD;Acc:S000002801]" Bcin12g00300 1012 CAZy : GH35PCW hemicellulose//SignalP-noTM//Early secretome Glycoside hydrolase, family 35 + Galactose-binding domain-like + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Beta-galactosidase, domain 2 + Glycoside hydrolase, family 35, conserved site + Beta-galactosidase jelly roll domain + Beta-galactosidase, domain 3 + Glycoside hydrolase 35, catalytic domain Bcin12g00310 181 "Bcmrps12, similar to yeast MRPS12, Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins [Source:SGD;Acc:S000005319]" Bcin12g00320 407 CAZy : GT15 Glycosyl transferase, family 15 + Nucleotide-diphospho-sugar transferases Bcin12g00330 815 "Bcpat1, similar to yeast PAT1, Deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; associated with topoisomerase II; binds to mRNAs under glucose starvation, most often in the 3' UTR; functionally linked to Pab1p; forms cytoplasmic foci upon DNA replication stress; phosphorylation by PKA inhibits P body foci formation [Source:SGD;Acc:S000000673]" Bcin12g00340 471 Domain of unknown function DUF3533 Bcin12g00350 414 SignalP-noTM Bcin12g00360 344 Formate/nitrite transporter + Aquaporin-like + Formate/nitrite transporter, conserved site Bcin12g00370 330 Alpha/Beta hydrolase fold Bcin12g00380 204 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Domain of unknown function DUF1524 Bcin12g00390 449 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Alcohol dehydrogenase GroES-associated N-terminal domain Bcin12g00400 316 Bcin12g00410 148 Effector(V2)|Effector(V1) Bcin12g00420 521 "Bcnmd3, similar to yeast NMD3, Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter protein for export of nascent ribosomal subunits through the nuclear pore complex [Source:SGD;Acc:S000001213]" Bcin12g00430 381 "Bcjlp1, similar to yeast JLP1, Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation [Source:SGD;Acc:S000003980]" Bcin12g00440 349 Bcin12g00450 653 "Bcgcn2, similar to yeast GCN2, Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691]" Bcin12g00460 719 Bcltf16, Light-responsive transcriptional regulator factor Bcin12g00470 376 Bcin12g00480 636 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin12g00490 324 Ubiquitin-like + Ubiquitin-related domain Bcin12g00500 153 Effector(V1) "Bcump1, similar to yeast UMP1, Chaperone required for correct maturation of the 20S proteasome; short-lived chaperone; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly [Source:SGD;Acc:S000000377]" Bcin12g00510 704 ABC transporter-like + AAA+ ATPase domain + P-loop containing nucleoside triphosphate hydrolase Bcin12g00520 220 Effector(V1) Bcprx2, Peroxiredoxin (AhpC/TSA family) Bcin12g00530 199 Bcin12g00540 1195 Zn2/Cys6 transcription factor "Bchst3, similar to yeast HST3, Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism [Source:SGD;Acc:S000005551]" Bcin12g00550 524 Proline dehydrogenase domain + Proline oxidase + FAD-linked oxidoreductase-like Bcin12g00560 326 Pyrroline-5-carboxylate reductase + 6-phosphogluconate dehydrogenase C-terminal domain-like + NAD(P)-binding domain + Pyrroline-5-carboxylate reductase, catalytic, N-terminal + Pyrroline-5-carboxylate reductase, dimerisation domain Bcin12g00570 127 Bcin12g00580 313 SignalP-noTM Bcin12g00590 264 Effector(V2)|Effector(V1) Ribonuclease H domain + Ribonuclease H-like domain Bcin12g00600 731 Bcin12g00610 458 Aminotransferase class V domain + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase Bcin12g00620 548 AMP-dependent synthetase/ligase Bcin12g00630 178 Bcin12g00640 290 Effector(V1) Bcin12g00650 435 Bcin12g00660 1475 GYF Bcin12g00670 960 "Bcemw1, similar to yeast EMW1, Essential conserved protein with a role in cell wall integrity; contains six TPR (tetratricopeptide repeat) domains clustered in the C-terminal region; conditional mutant is suppressed by overexpression of GFA1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005257]" Bcin12g00680 558 SM cluster NRPS2 Zinc finger, C2HC5-type Bcin12g00690 4919 SM cluster NRPS2 (KE) Bcnrps2, Nonribosomal peptide synthetase Bcin12g00700 1268 Transporter//SM cluster NRPS2 ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin12g00710 511 SM cluster NRPS2 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain + L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase Bcin12g00720 630 Bcyvc1, Ca2 channel protein Bcin12g00730 364 Bcin12g00740 284 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin12g00750 1310 Transporter "Bcspf1, similar to yeast SPF1, P-type ATPase, ion transporter of the ER membrane; required to maintain normal lipid composition of intracellular compartments and proper targeting of mitochondrial outer membrane tail-anchored proteins; involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1 [Source:SGD;Acc:S000000757]" Bcin12g00760 582 Xanthine/uracil/vitamin C permease Bcin12g00770 861 "Bcspo14, similar to yeast SPO14, Phospholipase D; catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis; participates in transcription initiation and/or early elongation of specific genes; interacts with foot domain of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions [Source:SGD;Acc:S000001739]" Bcin12g00780 392 Bcin12g00790 97 Effector(V2)|Effector(V1) Bcin12g00800 179 Bcin12g00810 117 Effector(V2)|Effector(V1) Bcin12g00820 869 "Bcswi6, similar to yeast SWI6, Transcription cofactor; forms complexes with Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; also binds Stb1p to regulate transcription at START; cell wall stress induces phosphorylation by Mpk1p, which regulates Swi6p localization; required for the unfolded protein response, independently of its known transcriptional coactivators [Source:SGD;Acc:S000004172]" Bcin12g00830 405 Bcin12g00840 199 GNAT domain + Acyl-CoA N-acyltransferase Bcin12g00850 355 Bcin12g00860 230 S-adenosyl-L-methionine-dependent methyltransferase Bcin12g00870 549 Transporter Amino acid/polyamine transporter I Bcin12g00880 322 Domain of unknown function DUF2422 Bcin12g00890 661 Brefeldin A sensitivity protein-related, domain of unknown function DUF2421 Bcin12g00900 311 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin12g00910 157 Effector(V2)|Effector(V1) Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein + Membrane associated eicosanoid/glutathione metabolism-like domain Bcin12g00920 320 Effector(V2) Zinc finger, C6HC-type + E3 ubiquitin ligase RBR family Bcin12g00930 401 CAZy : CBM50 Glycine zipper 2TM domain + Cyanovirin-N + LysM domain Bcin12g00940 417 Thiolase + Thiolase-like + Thiolase, conserved site + Thiolase, N-terminal + Thiolase, C-terminal Bcin12g00950 396 CAZy : GH5PCW/FCW //SignalP-noTM Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin12g00960 143 "Bcdib1, similar to yeast DIB1, 17-kDa component of the U4/U6aU5 tri-snRNP; plays an essential role in pre-mRNA splicing, orthologue of hDIM1, the human U5-specific 15-kDa protein [Source:SGD;Acc:S000006286]" Bcin12g00970 247 Bcgst19, Glutathione S-transferase Bcin12g00980 754 Effector(V2)|Effector(V1) Fungal N-terminal domain of STAND protein + Ankyrin repeat + Ankyrin repeat-containing domain Bcin12g00990 768 SignalP-noTM Ankyrin repeat + Ankyrin repeat-containing domain Bcin12g01000 449 "Bcpkp1, similar to yeast PKP1, Mitochondrial protein kinase; involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p [Source:SGD;Acc:S000001304]" Bcin12g01010 81 Effector(V1) Peptidase S8 propeptide/proteinase inhibitor I9 Bcin12g01020 365 yes SM cluster OAH Bcoah, Oxaloacetate acetylhydrolase Bcin12g01030 270 Protein of unknown function DUF1275 Bcin12g01040 1129 "Bcbms1, similar to yeast BMS1, GTPase required for ribosomal subunit synthesis and rRNA processing; required for synthesis of 40S ribosomal subunits and for processing the 35S pre-rRNA at sites A0, A1, and A2; interacts with Rcl1p, which stimulates its GTPase and U3 snoRNA binding activities; has similarity to Tsr1p [Source:SGD;Acc:S000006138]" Bcin12g01050 371 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin12g01060 431 Indoleamine 2,3-dioxygenase Bcin12g01070 475 Aminotransferase class V domain + Kynureninase + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin12g01080 468 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin12g01090 207 Bcin12g01100 444 CAZy : GH28PCW pectin//SignalP-noTM//Early secretome Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin12g01110 576 Zn2/Cys6 transcription factor Bcin12g01120 691 Bcin12g01130 523 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin12g01140 2366 Bcin12g01150 332 SignalP-noTM Bcin12g01160 509 CAZy : GT4 Glycosyl transferase, family 1 + Glycosyltransferase subfamily 4, N-terminal domain Bcin12g01170 624 UDP-glucose/GDP-mannose dehydrogenase, N-terminal + 6-phosphogluconate dehydrogenase C-terminal domain-like + UDP-glucose/GDP-mannose dehydrogenase, dimerisation + UDP-glucose/GDP-mannose dehydrogenase, C-terminal + NAD(P)-binding domain + UDP-glucose/GDP-mannose dehydrogenase + UDP-glucose 6-dehydrogenase, bacterial type Bcin12g01180 481 Bcin12g01190 634 Signaling pathway BcGPR1, G protein-coupled receptor (GPCR) : Git3, Git3_C Bcin12g01200 231 Bcin12g01210 192 Bcin12g01220 533 Senescence/spartin-associated Bcin12g01230 826 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin12g01240 503 Bcin12g01250 37 Bcin12g01260 471 Mitochondrial ribosomal protein MRP51, fungi Bcin12g01270 394 Protease Aspartic peptidase + Aspartic peptidase domain + Peptidase family A1 domain Bcin12g01280 1158 "Bcbbc1, similar to yeast BBC1, Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches [Source:SGD;Acc:S000003557]" Bcin12g01290 309 Protein of unknown function DUF408 Bcin12g01300 147 Effector(V1) Ribosomal protein S17e + Ribosomal protein S17e, conserved site Bcin12g01310 1193 Histone deacetylase superfamily + Histone deacetylase domain Bcin12g01320 409 tRNA-guanine(15) transglycosylase-like + Queuine tRNA-ribosyltransferase Bcin12g01330 261 Bcin12g01340 368 Bcgst13, Glutathione S-transferase Bcin12g01350 1038 "Bcuba1, similar to yeast UBA1, Ubiquitin activating enzyme (E1); involved in ubiquitin-mediated protein degradation and essential for viability; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001693]" Bcin12g01360 149 yes Effector(V2)|Effector(V1)//Signaling pathway Bcfkbp12, FK506-binding (FKBP12) peptidyl-prolylcis-transisomerase Bcin12g01370 1620 yes SignalP-noTM//Signaling pathway Bcmsb2, Signalin mucin Bcin12g01380 1168 CAZy : GT2 BcCHSII, Class II chitin synthase Bcin12g01390 250 Protease//Effector(V1) Glutamine amidotransferase + Class I glutamine amidotransferase-like Bcin12g01400 635 "Bcvba2, similar to yeast VBA2, Permease of basic amino acids in the vacuolar membrane [Source:SGD;Acc:S000000497]" Bcin12g01410 412 Protease Peptidase M20 + Peptidase M20, dimerisation domain + Peptidase M20A, amidohydrolase, predicted + Amidohydrolase Bcin12g01420 595 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin12g01430 640 Bcin12g01440 580 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin12g01450 413 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin12g01460 241 G-patch domain Bcin12g01470 2730 BTB/POZ-like + Histidine kinase-like ATPase, C-terminal domain + BTB/POZ fold Bcin12g01480 725 "Bcsec1, similar to yeast SEC1, Sm-like protein involved in docking and fusion of exocytic vesicles; binds to assembled SNARE complexes at the membrane and stimulates membrane fusion; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function; interacts directly with essential exocyst subunit Sec6p [Source:SGD;Acc:S000002571]" Bcin12g01490 786 Bcin12g01500 1133 "Bcurb1, similar to yeast URB1, Protein required for the normal accumulation of 25S and 5.8S rRNAs; nucleolar protein; associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit [Source:SGD;Acc:S000001497]" Bcin12g01510 1909 "Bciml1, similar to yeast IML1, GTPase-activating protein (GAP), subunit of SEA and Iml1p complexes; SEA (Seh1-associated) complex is a coatomer-related complex that associates dynamically with the vacuole; Iml1p complex (Iml1p-Npr2p-Npr3p) is required for non-nitrogen-starvation (NNS)-induced autophagy; localized to either pre-autophagosomal structures (PAS) or non-PAS structures during NNS-induced autophagy; [Source:SGD;Acc:S000003899]" Bcin12g01520 1048 SignalP-noTM Bcgo2, Glyoxal oxidase 2 Bcin12g01530 485 CAZy : GH16FCW Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin12g01540 938 CAZy : GTnc Glycosyltransferase 2-like + Nucleotide-diphospho-sugar transferases Bcin12g01550 840 "Bcsuv3, similar to yeast SUV3, ATP-dependent RNA helicase; component of the mitochondrial degradosome along with the RNase Dss1p; the degradosome associates with the ribosome and mediates RNA turnover; also required during splicing of the COX1 AI5_beta intron [Source:SGD;Acc:S000005950]" Bcin12g01560 245 "Bcnyv1, similar to yeast NYV1, v-SNARE component of the vacuolar SNARE complex; involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane [Source:SGD;Acc:S000004083]" Bcin12g01570 194 Bcin12g01580 574 "Bccca1, similar to yeast CCA1, ATP (CTP):tRNA-specific tRNA nucleotidyltransferase; different forms targeted to the nucleus, cytosol, and mitochondrion are generated via the use of multiple transcriptional and translational start sites [Source:SGD;Acc:S000000970]" Bcin12g01590 789 "Bctrs85, similar to yeast TRS85, Component of transport protein particle (TRAPP) complex III; TRAPPIII is a multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating endosome-Golgi traffic and required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role [Source:SGD;Acc:S000002515]" Bcin12g01600 100 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin12g01610 291 DnaJ domain Bcin12g01620 111 Effector(V2)|Effector(V1) Bcin12g01630 564 Armadillo-like helical + Armadillo-type fold + Protein of unknown function DUF2454 Bcin12g01640 1077 "Bcfig4, similar to yeast FIG4, Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase; required for efficient mating and response to osmotic shock; physically associates with and regulated by Vac14p; contains a SAC1-like domain; homologous to human FIG4, which is associated with CMT4J, a form of Charcot-Marie-Tooth disorder [Source:SGD;Acc:S000005269]" Bcin12g01650 459 Snf7 family Bcin12g01660 154 Effector(V2)|Effector(V1) Bcin12g01670 494 "Bcrad18, similar to yeast RAD18, E3 ubiquitin ligase; forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair; SUMO-targeted ubiquitin ligase (STUbl) that contains a SUMO-interacting motif (SIM) which stimulates its ubiquitin ligase activity towards the sumoylated form of PCNA [Source:SGD;Acc:S000000662]" Bcin12g01680 460 DNA polymerase subunit Cdc27 Bcin12g01690 546 CAZy : GH125 //SignalP-noTM Uncharacterised conserved protein UCP028846 + Six-hairpin glycosidase-like + Six-hairpin glycosidase Bcin12g01700 740 Bcin12g01710 1032 PAS domain + Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily Bcin12g01720 296 Bcin12g01730 155 Bcin12g01740 179 Bcin12g01750 292 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin12g01760 289 "Bcrfa2, similar to yeast RFA2, Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; in concert with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication s [Source:SGD;Acc:S000005256]" Bcin12g01770 257 GNAT domain + Acyl-CoA N-acyltransferase Bcin12g01780 254 "Bcidi1, similar to yeast IDI1, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase; catalyzes an essential activation step in the isoprenoid biosynthetic pathway; required for viability; isopentenyl diphosphate:dimethylallyl diphosphate isomerase is also known as IPP isomerase [Source:SGD;Acc:S000006038]" Bcin12g01790 670 "Bcsyo1, similar to yeast SYO1, Transport adaptor or symportin; facilitates synchronized nuclear coimport of the two 5S-rRNA binding proteins Rpl5p and Rpl11p; required for biogenesis of the large ribosomal subunit; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus [Source:SGD;Acc:S000002221]" Bcin12g01800 377 Bcin12g01810 920 "Bcdbp10, similar to yeast DBP10, Putative ATP-dependent RNA helicase of the DEAD-box protein family; constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis [Source:SGD;Acc:S000002189]" Bcin12g01820 799 "Bchca4, similar to yeast HCA4, DEAD box RNA helicase; component of the SSU; interacts with Bfr2p and Enp2p; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis [Source:SGD;Acc:S000003570]" Bcin12g01830 319 "Bcfad1, similar to yeast FAD1, Flavin adenine dinucleotide (FAD) synthetase; performs the second step in synthesis of FAD from riboflavin [Source:SGD;Acc:S000002203]" Bcin12g01840 760 SUN domain Bcin12g01850 852 Bcin12g01860 375 "Bcgal10, similar to yeast GAL10, UDP-glucose-4-epimerase; catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes the conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers [Source:SGD;Acc:S000000223]" Bcin12g01870 329 "Bczta1, similar to yeast ZTA1, NADPH-dependent quinone reductase; GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin [Source:SGD;Acc:S000000250]" Bcin12g01880 474 Major facilitator superfamily + Major facilitator superfamily domain Bcin12g01890 396 Protein kinase domain + Protein kinase-like domain Bcin12g01900 241 Bcin12g01910 396 Bcin12g01920 1887 "Bcscc2, similar to yeast SCC2, Subunit of cohesin loading factor (Scc2p-Scc4p); a complex required for loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX; evolutionarily-conserved adherin; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002588]" Bcin12g01930 121 Effector(V2)|Effector(V1) "Bcrpa12, similar to yeast RPA12, RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex [Source:SGD;Acc:S000003824]" Bcin12g01940 340 "Bclia1, similar to yeast LIA1, Deoxyhypusine hydroxylase; HEAT-repeat containing metalloenzyme that catalyzes hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003831]" Bcin12g01950 284 O-methyltransferase, family 3 + S-adenosyl-L-methionine-dependent methyltransferase Bcin12g01960 510 Effector(V2)|Effector(V1) 3-dehydroquinate synthase domain Bcin12g01970 708 Bcin12g01980 490 Bcin12g01990 272 Pleckstrin homology-like domain + Adaptin ear-binding coat-associated protein 1 NECAP-1 Bcin12g02000 375 "Bcgcn3, similar to yeast GCN3, Alpha subunit of translation initiation factor eIF2B; guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; positive regulator of GCN4 expression; assembles into filaments with Gcd2p, Gcd6p, Gcd7p, and Sui2p as cells approach stationary phase and under cytosolic acidification and starvation conditions [Source:SGD;Acc:S000001734]" Bcin12g02010 141 SignalP-TM//Effector(V1) Bcin12g02020 231 "Bcpop4, similar to yeast POP4, Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; binds to the RPR1 RNA subunit in RNase P [Source:SGD;Acc:S000000461]" Bcin12g02030 819 Phospholipid/glycerol acyltransferase + Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase Bcin12g02040 389 yes Protease//SignalP-noTM//Early secretome Bcap8, Aspartic proteinase Bcin12g02050 350 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin12g02060 966 Zn2/Cys6 + fungal trans transcription factor BcxlnR, Zn2/Cys6 transcription factor Bcin12g02070 829 Sulphate anion transporter + STAS domain + Sulphate transporter Bcin12g02080 276 Crotonase superfamily + Enoyl-CoA hydratase/isomerase, conserved site + ClpP/crotonase-like domain Bcin12g02090 824 Tetrapeptide transporter, OPT1/isp4 + Oligopeptide transporter, OPT superfamily Bcin12g02100 474 Bcin12g02110 1219 Folliculin-interacting protein, N-terminal domain Bcin12g02120 582 SignalP-noTM Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin12g02130 66 Effector(V1) Bcin12g02140 381 Bcin12g02150 753 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin12g02160 530 "Bcula1, similar to yeast ULA1, Protein that activates Rub1p (NEDD8) before neddylation; acts together with Uba3p; may play a role in protein degradation [Source:SGD;Acc:S000005924]" Bcin12g02170 344 "Bcrki1, similar to yeast RKI1, Ribose-5-phosphate ketol-isomerase; catalyzes the interconversion of ribose 5-phosphate and ribulose 5-phosphate in the pentose phosphate pathway; participates in pyridoxine biosynthesis [Source:SGD;Acc:S000005621]" Bcin12g02180 800 Heterokaryon incompatibility Bcin12g02190 565 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin12g02200 399 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site Bcin12g02210 563 Bcin12g02220 200 Effector(V2)|Effector(V1) Bcin12g02230 657 Bcin12g02240 859 Domain of unknown function DUF221 + Protein of unknown function DUF3779, phosphate metabolism + Domain of unknown function DUF4463 + Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain Bcin12g02250 262 DnaJ domain Bcin12g02260 436 "Bcpph3, similar to yeast PPH3, Catalytic subunit of protein phosphatase PP4 complex; Pph3p and Psy2p form active complex, Psy4p may provide substrate specificity; regulates recovery from the DNA damage checkpoint, the gene conversion- and single-strand annealing-mediated pathways of meiotic double-strand break repair and efficient Non-Homologous End-Joining (NHEJ) pathway; involved in activation of Gln3p to alleviate nitrogen catabolite repression; Pph3p and Psy2p localize to foci on meiotic chromosomes [Source:SGD;Acc:S000002482]" Bcin12g02270 153 SignalP-noTM//Effector(V1) Bcin12g02280 1431 Bcin12g02290 362 Bcin12g02300 544 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin12g02310 1446 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead + 2Fe-2S ferredoxin-type domain + Molybdopterin dehydrogenase, FAD-binding + [2Fe-2S]-binding + CO dehydrogenase flavoprotein, C-terminal + 2Fe-2S ferredoxin, iron-sulphur binding site + Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding + Beta-grasp domain + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 + Aldehyde oxidase/xanthine dehydrogenase + Oxidoreductase, molybdopterin binding site Bcin12g02320 627 Monooxygenase, FAD-binding + Thioredoxin-like fold + Phenol hydroxylase, C-terminal dimerisation domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g02330 478 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g02340 453 "Bccds1, similar to yeast CDS1, Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids [Source:SGD;Acc:S000000233]" Bcin12g02350 730 Protein of unknown function DUF3636 Bcin12g02360 254 Bcin12g02370 422 Bcin12g02380 547 Protease Aspartic peptidase domain + Peptidase family A1 domain Bcin12g02390 597 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g02400 284 Putative amidoligase enzyme Bcin12g02410 652 Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, PHD-type, conserved site + Zinc finger, PHD-finger + Transcription factor NFX1 family Bcin12g02420 367 Bcin12g02430 810 Aminotransferase class-III + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase + Major intrinsic protein, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin12g02440 483 Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin12g02450 414 "Bcbio2, similar to yeast BIO2, Biotin synthase; catalyzes the conversion of dethiobiotin to biotin, which is the last step of the biotin biosynthesis pathway; complements E. coli bioB mutant [Source:SGD;Acc:S000003518]" Bcin12g02460 358 GDP-fucose transporter Bcin12g02470 75 Bcin12g02480 220 Bcin12g02490 284 Bcin12g02500 227 Effector(V1) Bcin12g02510 636 "Bcvps36, similar to yeast VPS36, Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome; plays a role in the formation of mutant huntingtin (Htt) aggregates in yeast [Source:SGD;Acc:S000004409]" Bcin12g02520 524 "Bcthp3, similar to yeast THP3, Protein that may have a role in transcription elongation; forms a complex with Csn12p that is recruited to transcribed genes; possibly involved in splicing based on pre-mRNA accumulation defect for many intron-containing genes [Source:SGD;Acc:S000006249]" Bcin12g02530 625 yes Signaling pathway BcBem1, Scaffold protein Bcin12g02540 386 Transposase, MuDR, plant Bcin12g02550 356 "Bccdc21, similar to yeast CDC21, Thymidylate synthase; required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S [Source:SGD;Acc:S000005600]" Bcin12g02560 287 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin12g02570 435 Bacterial transferase hexapeptide repeat + Trimeric LpxA-like + Hexapeptide transferase, conserved site Bcin12g02580 229 Effector(V2)|Effector(V1) Bacterial transferase hexapeptide repeat + Trimeric LpxA-like + Hexapeptide transferase, conserved site Bcin12g02590 230 Effector(V2)|Effector(V1) Bacterial transferase hexapeptide repeat + Trimeric LpxA-like + Hexapeptide transferase, conserved site Bcin12g02600 279 Effector(V2) Mitochondrial 18kDa protein Bcin12g02610 82 Effector(V2)|Effector(V1) Protein of unknown function DUF2611 Bcin12g02620 88 Effector(V2)|Effector(V1) Bcin12g02630 185 "Bcemc4, similar to yeast EMC4, Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; homologous to worm ZK616.6/EMC-4, fly CG11137, human TMM85 [Source:SGD;Acc:S000003200]" Bcin12g02640 705 "Bcapl1, similar to yeast APL1, Beta-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport; similar to mammalian beta-chain of the clathrin associated protein complex [Source:SGD;Acc:S000003765]" Bcin12g02650 161 Interferon alpha-inducible protein 6/27 Bcin12g02660 283 NAD(P)-binding domain Bcin12g02670 144 Effector(V1) "Bcaim7, similar to yeast AIM7, Protein that interacts with Arp2/3 complex; interacts with Arp2/3 complex to stimulate actin filament debranching and inhibit actin nucleation; has similarity to Cof1p and also to human glia maturation factor (GMF); null mutant displays elevated mitochondrial genome loss [Source:SGD;Acc:S000002470]" Bcin12g02680 516 Transporter "Bcjen1, similar to yeast JEN1, Monocarboxylate/proton symporter of the plasma membrane; transport activity is dependent on the pH gradient across the membrane; mediates high-affinity uptake of carbon sources lactate, pyuvate, and acetate, and also of the micronutrient selenite, whose structure mimics that of monocarboxylates; expression and localization are tightly regulated, with transcription repression, mRNA degradation, and protein endocytosis and degradation all occurring in the presence of glucose [Source:SGD;Acc:S000001700]" Bcin12g02690 707 Bcin12g02700 713 Nucleoside phosphatase GDA1/CD39 Bcin12g02710 521 Bcin12g02720 317 "Bcmtr3, similar to yeast MTR3, Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hMtr3p (EXOSC6) [Source:SGD;Acc:S000003390]" Bcin12g02730 52 Bcin12g02740 83 Effector(V2) Bcin12g02750 402 yes Bcelp4, Elongator complex protein 4 Bcin12g02760 151 Effector(V2)|Effector(V1) "Bcrpb8, similar to yeast RPB8, RNA polymerase subunit ABC14.5; common to RNA polymerases I, II, and III [Source:SGD;Acc:S000005750]" Bcin12g02770 328 NUDIX hydrolase domain + NUDIX hydrolase domain-like + Domain of unknown function DUF4743 Bcin12g02780 240 "Bcopi10, similar to yeast OPI10, Protein with a possible role in phospholipid biosynthesis; null mutant displays an inositol-excreting phenotype that is suppressed by exogenous choline; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005392]" Bcin12g02790 983 Bcin12g02800 305 "Bcsen34, similar to yeast SEN34, Subunit of the tRNA splicing endonuclease; tRNA splicing endonuclease is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease [Source:SGD;Acc:S000000066]" Bcin12g02810 481 CAZy : GT62 Nucleotide-diphospho-sugar transferases Bcin12g02820 1610 Sec7 domain + Armadillo-type fold + Sec7 domain, alpha orthogonal bundle + Guanine nucleotide exchange factor, N-terminal Bcin12g02830 820 CAZy : GH3PCW/FCW Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Fibronectin type III-like domain Bcin12g02840 100 Effector(V1) Acylphosphatase-like domain + Acylphosphatase, conserved site + Acylphosphatase Bcin12g02850 716 "Bcesf1, similar to yeast ESF1, Nucleolar protein involved in pre-rRNA processing; depletion causes severely decreased 18S rRNA levels [Source:SGD;Acc:S000002773]" Bcin12g02860 315 Bcin12g02870 244 Bcin12g02880 312 Fucose-specific lectin Bcin12g02890 459 WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin12g02900 1005 Bcin12g02910 796 CAZy : AA8,AA3 //SignalP-noTM//Early secretome Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Cellobiose dehydrogenase, cytochrome domain + NAD(P)-binding domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g02920 394 Taurine catabolism dioxygenase TauD/TfdA Bcin12g02930 515 Nucleoporin p58/p45 + Nucleoporin FG repeat Bcin12g02940 315 "Bcfip1, similar to yeast FIP1, Subunit of cleavage polyadenylation factor (CPF); interacts directly with poly(A) polymerase (Pap1p) to regulate its activity; bridging factor that links Pap1p and the CPF complex via Yth1p [Source:SGD;Acc:S000003853]" Bcin12g02950 694 Bcin12g02960 279 HAD hydrolase, subfamily IA + HAD-like domain Bcin12g02970 283 Tetratricopeptide-like helical domain Bcin12g02980 147 Bcin12g02990 371 XAP5 protein Bcin12g03000 844 Phospholipase D/Transphosphatidylase + Phospholipase D-like domain Bcin12g03010 492 Leucine-rich repeat domain, L domain-like Bcin12g03020 877 "Bcdbp7, similar to yeast DBP7, Putative ATP-dependent RNA helicase of the DEAD-box family; involved in ribosomal biogenesis; required at post-transcriptional step for efficient retrotransposition; essential for growth under anaerobic conditions [Source:SGD;Acc:S000001732]" Bcin12g03030 380 "Bcpan6, similar to yeast PAN6, Pantothenate synthase; also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC [Source:SGD;Acc:S000001407]" Bcin12g03040 223 SignalP-noTM Bcin12g03050 340 Centromere subunit L Bcin12g03060 492 Transcription factor Nrm1/Whi5 Bcin12g03070 359 Bcin12g03080 116 Bcin12g03090 154 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2) Bcin12g03100 308 "Bchis2, similar to yeast HIS2, Histidinolphosphatase; catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control [Source:SGD;Acc:S000001921]" Bcin12g03110 654 Multi antimicrobial extrusion protein Bcin12g03120 171 Domain of unknown function DUF202 Bcin12g03130 965 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g03140 742 "Bcmlh1, similar to yeast MLH1, Protein required for mismatch repair in mitosis and meiosis; also required for crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; human homolog is associated with hereditary non-polyposis colon cancer [Source:SGD;Acc:S000004777]" Bcin12g03150 907 "Bcrpn1, similar to yeast RPN1, Non-ATPase base subunit of the 19S RP of the 26S proteasome; may participate in the recognition of several ligands of the proteasome; contains a leucine-rich repeat (LRR) domain, a site for protein-protein interactions; RP is the acronym for regulatory particle [Source:SGD;Acc:S000001069]" Bcin12g03160 419 "Bcrio2, similar to yeast RIO2, Essential serine kinase involved in the processing of 20S pre-rRNA; involved in the processing of the 20S pre-rRNA into mature 18S rRNA; has similarity to Rio1p [Source:SGD;Acc:S000005151]" Bcin12g03170 607 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin12g03180 692 yes Bccpr1, NADPH cytochrome P450 oxidoreductase Bcin12g03190 2537 "Bctao3, similar to yeast TAO3, Component of the RAM signaling network; is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with protein kinase Cbk1p and also with Kic1p [Source:SGD;Acc:S000001391]" Bcin12g03200 706 SignalP-noTM Bcin12g03210 909 Protease Peptidase S16, lon N-terminal + AAA+ ATPase domain + ATPase, AAA-type, core + Lon protease, bacterial/eukaryotic-type + Peptidase S16, Lon C-terminal + Ribosomal protein S5 domain 2-type fold, subgroup + PUA-like domain + Ribosomal protein S5 domain 2-type fold + Lon protease + P-loop containing nucleoside triphosphate hydrolase + Lon protease homologue 2, peroxisomal Bcin12g03220 617 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin12g03230 753 Ankyrin repeat + Heterokaryon incompatibility + Ankyrin repeat-containing domain Bcin12g03240 530 ATP-grasp fold + NAD(P)-binding domain Bcin12g03250 604 Zinc finger, RanBP2-type + 4'-phosphopantetheinyl transferase superfamily Bcin12g03260 292 Protein of unknown function DUF1774, fungi Bcin12g03270 387 Protease//SignalP-noTM Peptidase M28 Bcin12g03280 318 Single-stranded nucleic acid binding R3H + R3H-associated N-terminal domain Bcin12g03290 564 "Bcafg1, similar to yeast AFG1, Protein that may act as a chaperone for cytochrome c oxidase subunits; conserved protein; may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane; member of the AAA family but lacks a protease domain [Source:SGD;Acc:S000000778]" Bcin12g03300 299 Bcin12g03310 275 Cys2His2 transcription factor//Effector(V2)|Effector(V1) Zinc finger, C2H2 + Zinc finger, C2H2-like Bcin12g03320 323 Cys2His2 transcription factor//Effector(V1) Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like + Zinc finger, double-stranded RNA binding Bcin12g03330 984 Cys2His2 transcription factor + Fungal_trans Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin12g03340 311 Effector(V2) "Bccuz1, similar to yeast CUZ1, Protein with a role in the ubiquitin-proteasome pathway; interacts with ubiquitinated protein, Cdc48p and the proteasomal regulatory particle; may protect cells from trivalent metalloid induced proteotoxicity; contains a PACE promoter element and is co-regulated with proteasome subunit genes; AN1-type zinc finger protein, with DHHC and ubiquitin-like domains (UBL); ortholog of ZFAND1, a human gene linked to cancer; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000005099]" Bcin12g03350 1094 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin12g03360 350 Bcin12g03370 374 Six-bladed beta-propeller, TolB-like + SMP-30/Gluconolactonase/LRE-like region Bcin12g03380 268 SignalP-noTM Bcin12g03390 615 CAZy : GH15,CBM20Energy //SignalP-noTM//Early secretome Glucoamylase + Carbohydrate binding module family 20 + Glucoamylase, starch-binding + Six-hairpin glycosidase-like + Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family + Six-hairpin glycosidase + Immunoglobulin-like fold + Carbohydrate-binding-like fold Bcin12g03400 744 Gamma-tubulin complex component protein Bcin12g03410 269 Effector(V2) Interferon alpha-inducible protein 6/27 Bcin12g03420 208 SignalP-noTM Interferon alpha-inducible protein 6/27 Bcin12g03430 493 SignalP-noTM Alpha/Beta hydrolase fold Bcin12g03440 136 Bcin12g03450 463 Bcin12g03460 236 Bcin12g03470 634 DnaJ domain Bcin12g03480 987 "Bccho2, similar to yeast CHO2, Phosphatidylethanolamine methyltransferase (PEMT); catalyzes the first step in the conversion of phosphatidylethanolamine to phosphatidylcholine during the methylation pathway of phosphatidylcholine biosynthesis [Source:SGD;Acc:S000003389]" Bcin12g03490 343 "Bcnbp35, similar to yeast NBP35, Essential cytoplasmic iron-sulfur cluster binding protein; forms a complex with Cfd1p that is involved in iron-sulfur protein assembly in the cytosol; similar to P-loop NTPases [Source:SGD;Acc:S000003059]" Bcin12g03500 404 Bcin12g03510 67 Effector(V2)|Effector(V1) Bcin12g03520 355 SignalP-noTM//Early secretome Six-bladed beta-propeller, TolB-like Bcin12g03530 649 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin12g03540 381 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin12g03550 151 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2) Bcspl2, Cerato-platanin gene Bcin12g03560 346 Effector(V1) GNAT domain + Acyl-CoA N-acyltransferase Bcin12g03570 343 Effector(V2) 3-hydroxyisobutyrate dehydrogenase-related, conserved site + 6-phosphogluconate dehydrogenase, NADP-binding + 6-phosphogluconate dehydrogenase C-terminal domain-like + 3-hydroxyisobutyrate dehydrogenase + 6-phosphogluconate dehydrogenase, domain 2 + 3-hydroxyisobutyrate dehydrogenase-related + NAD(P)-binding domain + 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain Bcin12g03580 1157 Cleavage/polyadenylation specificity factor, A subunit, C-terminal + Quinonprotein alcohol dehydrogenase-like superfamily + WD40/YVTN repeat-like-containing domain + DNA damage-binding protein 1 Bcin12g03590 335 DNA-directed RNA polymerase III subunit Rpc5 Bcin12g03600 159 Effector(V2)|Effector(V1) Proteolipid membrane potential modulator Bcin12g03610 461 "Bcclp1, similar to yeast CLP1, Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; involved in both the endonucleolyitc cleavage and polyadenylation steps of mRNA 3'-end maturation and in gene looping which affects reinitiation of transcription [Source:SGD;Acc:S000005776]" Bcin12g03620 347 "Bcarg82, similar to yeast ARG82, Inositol polyphosphate multikinase (IPMK); sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes [Source:SGD;Acc:S000002580]" Bcin12g03630 582 Argonaute complex, subunit Arb1 Bcin12g03640 493 Major facilitator superfamily + Major facilitator superfamily domain Bcin12g03650 376 NADP-dependent oxidoreductase domain Bcin12g03660 564 Bcin12g03670 175 Effector(V1) Bcin12g03680 355 Semialdehyde dehydrogenase, NAD-binding + NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin12g03690 457 SignalP-noTM//Early secretome Nitrous oxide reductase, N-terminal + WD40/YVTN repeat-like-containing domain + Lactonase, 7-bladed beta propeller Bcin12g03700 694 Bcnde1, External NADH dehydrogenase Bcin12g03710 262 Effector(V1) LIS1 homology motif + CTLH, C-terminal LisH motif + CRA domain + CTLH/CRA C-terminal to LisH motif domain Bcin12g03720 447 Uridine kinase like + AAA+ ATPase domain + Phosphoribulokinase/uridine kinase + P-loop containing nucleoside triphosphate hydrolase + Phosphoribosyltransferase-like Bcin12g03730 607 Transporter Amino acid transporter, transmembrane domain Bcin12g03740 1553 "Bcmet5, similar to yeast MET5, Sulfite reductase beta subunit; involved in amino acid biosynthesis, transcription repressed by methionine [Source:SGD;Acc:S000003898]" Bcin12g03750 321 Protein of unknown function DUF1753, Golgi Bcin12g03760 207 Effector(V2)|Effector(V1) Small GTPase superfamily + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin12g03770 437 yes Bcnop53, pre-rRNA processing factor Bcin12g03780 110 Effector(V2)|Effector(V1) Bcin12g03790 847 "Bcgef1, similar to yeast GEF1, Voltage-gated chloride channel; localized to the golgi, the endosomal system, and plasma membrane; involved in cation homeostasis; highly homologous to vertebrate voltage-gated chloride channels; modulates TBSV model (+) RNA virus replication by regulating copper metabolism [Source:SGD;Acc:S000003801]" Bcin12g03800 213 Bcin12g03810 422 Bcin12g03820 268 Bcin12g03830 513 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin12g03840 207 GNAT domain + Acyl-CoA N-acyltransferase Bcin12g03850 210 Effector(V2)|Effector(V1) S-adenosyl-L-methionine-dependent methyltransferase Bcin12g03860 803 "Bctyw1, similar to yeast TYW1, Iron-sulfer protein required for synthesis of Wybutosine modified tRNA; Wybutosine is a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions; induction by Yap5p in response to iron provides protection from high iron toxicity; overexpression results in increased cellular iron [Source:SGD;Acc:S000006128]" Bcin12g03870 536 FHY3/FAR1 family Bcin12g03880 331 yes Signaling pathway Bcpp2Ac, Similar to serine/threonine protein phosphatase 2A catalytic subunit Bcin12g03890 666 Cullin repeat-like-containing domain + Exocyst component Exo84, C-terminal + Exocyst complex component Exo84 Bcin12g03900 172 Effector(V2)|Effector(V1) "Bctom20, similar to yeast TOM20, Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins [Source:SGD;Acc:S000003314]" Bcin12g03910 4345 "Bcdyn1, similar to yeast DYN1, Cytoplasmic heavy chain dynein; microtubule motor protein; member of the AAA+ protein family, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p; motility along microtubules inhibited by She1p [Source:SGD;Acc:S000001762]" Bcin12g03920 437 CAZy : AA9,CBM18 //SignalP-noTM Chitin-binding, type 1 + Glycoside hydrolase, family 61 Bcin12g03930 104 Effector(V2)|Effector(V1) "Bchsp10, similar to yeast HSP10, Mitochondrial matrix co-chaperonin; inhibits the ATPase activity of Hsp60p, a mitochondrial chaperonin; involved in protein folding and sorting in the mitochondria; 10 kD heat shock protein with similarity to E. coli groES [Source:SGD;Acc:S000005546]" Bcin12g03940 761 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin12g03950 152 Effector(V2)|Effector(V1) "Bcmrpl19, similar to yeast MRPL19, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000005129]" Bcin12g03960 382 Oxidative stress survival, Svf1-like + Svf1-like, C-terminal Bcin12g03970 138 Effector(V1) Histone H4 + TATA box binding protein associated factor (TAF) + Histone-fold Bcin12g03980 145 SignalP-TM Proteolipid membrane potential modulator Bcin12g03990 921 SNF2-related + Helicase, C-terminal + Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Helicase superfamily 1/2, ATP-binding domain + HIRAN domain + P-loop containing nucleoside triphosphate hydrolase Bcin12g04000 348 Bcin12g04010 252 Bcin12g04020 324 Bcin12g04030 114 Effector(V2)|Effector(V1) "Bctoa2, similar to yeast TOA2, TFIIA small subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; required, along with Toa1p, for ribosomal protein gene transcription in vivo; homologous to smallest subunit of human and Drosophila TFIIA; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001541]" Bcin12g04040 198 "Bcvma16, similar to yeast VMA16, Subunit c'' of the vacuolar ATPase; v-ATPase functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain [Source:SGD;Acc:S000001068]" Bcin12g04050 464 Bcin12g04060 677 MoaB/Mog domain + MoeA, N-terminal and linker domain + MoeA, C-terminal, domain IV + Molybdenum cofactor biosynthesis, conserved site Bcin12g04070 188 Effector(V2)|Effector(V1) "Bcpop5, similar to yeast POP5, Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs [Source:SGD;Acc:S000000031]" Bcin12g04080 350 "Bcgpn2, similar to yeast GPN2, Putative GTPase with a role in biogenesis of RNA pol II and polIII; may be involved in assembly of RNA polymerases II and III and in their transport into the nucleus; contains a Gly-Pro-Asn motif in the G domain; similar to Npa3p and Gpn3p; highly conserved across species and homologous to human gene GPN2/ATPBD1B; required for establishment of sister chromatid cohesion [Source:SGD;Acc:S000005788]" Bcin12g04090 343 "Bcbub3, similar to yeast BUB3, Kinetochore checkpoint WD40 repeat protein; localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p [Source:SGD;Acc:S000005552]" Bcin12g04100 1058 Bcin12g04110 452 Transcription regulator HTH, APSES-type DNA-binding domain + KilA, N-terminal/APSES-type HTH, DNA-binding Bcin12g04120 199 "Bcrdi1, similar to yeast RDI1, Rho GDP dissociation inhibitor; involved in the localization and regulation of Cdc42p and Rho1p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002294]" Bcin12g04130 322 Calcineurin-like phosphoesterase domain, apaH type + Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase + Metallo-dependent phosphatase-like Bcin12g04140 929 Zinc finger, CCHC-type Bcin12g04150 825 Clathrin/coatomer adaptor, adaptin-like, N-terminal + Armadillo-like helical + Armadillo-type fold + AP complex subunit beta + AP-3 complex subunit beta Bcin12g04160 279 Bcin12g04170 461 "Bcnuf2, similar to yeast NUF2, Component of the kinetochore-associated Ndc80 complex; involved in chromosome segregation, spindle checkpoint activity, and kinetochore clustering; evolutionarily conserved; other members include Ndc80p, Nuf2p, Spc24p, and Spc25p [Source:SGD;Acc:S000005430]" Bcin12g04180 865 Sulfatase-modifying factor enzyme + C-type lectin fold + SAM-dependent methyltransferase, EsaF-type, putative + Histidine-specific methyltransferase, SAM-dependent + S-adenosyl-L-methionine-dependent methyltransferase Bcin12g04190 572 Bcin12g04200 66 Effector(V1) Bcin12g04210 625 GATA zinc finger transcription factor Bir1, GATA zinc finger transcription factor Bcin12g04220 130 Effector(V1) "Bctvp15, similar to yeast TVP15, Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p [Source:SGD;Acc:S000002507]" Bcin12g04230 241 Bcin12g04240 357 Bcdao1, D-amino acid oxidase Bcin12g04250 252 HAD hydrolase, subfamily IA + HAD-like domain Bcin12g04260 316 FAD linked oxidase, N-terminal + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin12g04270 820 Bcin12g04280 141 yes Effector(V2)|Effector(V1)//Early secretome Bctrx1, Thioredoxin Bcin12g04290 614 Regulator of chromosome condensation, RCC1 + Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II Bcin12g04300 526 Bcin12g04310 311 Bcin12g04320 635 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin12g04330 592 Protease Xaa-Pro dipeptidyl-peptidase-like domain + CocE/Serine esterase + Galactose-binding domain-like + Xaa-Pro dipeptidyl-peptidase, C-terminal + Alpha/Beta hydrolase fold Bcin12g04340 198 Effector(V1) Bcin12g04350 626 Bcin12g04360 209 Effector(V2)|Effector(V1) Zinc finger, CCHC-type Bcin12g04370 178 Chromo/chromo shadow domain + Chromo domain-like Bcin12g04380 1067 ABC transporter-like + AAA+ ATPase domain + Armadillo-like helical + Elongation Factor 3 + Armadillo-type fold + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase + TOG domain Bcin12g04390 674 SignalP-noTM Six-bladed beta-propeller, TolB-like + WD40-like Beta Propeller + WD40/YVTN repeat-like-containing domain Bcin12g04400 398 Bcin12g04410 291 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa S1/P1 nuclease + Phospholipase C/P1 nuclease domain Bcin12g04420 823 Bcin12g04430 1399 "Bcrpo41, similar to yeast RPO41, Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition; Mtf1p interacts with and stabilizes the Rpo41p-promoter complex, enhancing DNA bending and melting to facilitate pre-initiation open complex formation [Source:SGD;Acc:S000001858]" Bcin12g04440 233 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin12g04450 783 "Bccef1, similar to yeast CEF1, Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association, evolutionarily conserved and homologous to S. pombe Cdc5p [Source:SGD;Acc:S000004826]" Bcin12g04460 600 Hexokinase + Hexokinase, N-terminal + Hexokinase, C-terminal Bcin12g04470 268 Effector(V2) Gamma interferon inducible lysosomal thiol reductase GILT Bcin12g04480 324 Scavenger mRNA decapping enzyme DcpS/DCS2 + Scavenger mRNA decapping enzyme, N-terminal + HIT-like domain Bcin12g04490 569 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin12g04500 914 Zn2/Cys6 + fungal trans transcription factor Bcnit4, Zn2/Cys6 transcription factor Bcin12g04510 1479 PAS domain + Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily Bcin12g04520 429 Bcin12g04530 437 CAZy : GH28PCW pectin//SignalP-noTM//Early secretome Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin12g04540 288 FMN-binding split barrel + Pyridoxamine 5'-phosphate oxidase, Alr4036 family, FMN-binding domain Bcin12g04550 455 Bcin12g04560 416 Bcgst24, Glutathione S-transferase, tRNA binding domain Bcin12g04570 526 Effector(V2)|Effector(V1) "Bcerg8, similar to yeast ERG8, Phosphomevalonate kinase; an essential cytosolic enzyme that acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate [Source:SGD;Acc:S000004833]" Bcin12g04580 1178 Pentatricopeptide repeat + Tetratricopeptide-like helical domain + Pentacotripeptide-repeat region of PROPR Bcin12g04590 807 XPG/Rad2 endonuclease + 5'-3' exonuclease, C-terminal domain + XPG N-terminal + XPG-I domain + PIN domain-like Bcin12g04600 597 XPG/Rad2 endonuclease + XPG-I domain + 5'-3' exonuclease, C-terminal domain + PIN domain-like Bcin12g04610 552 SignalP-TM Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin12g04620 120 Bcin12g04630 453 SignalP-noTM Lipase, secreted + Alpha/Beta hydrolase fold Bcin12g04640 483 SignalP-noTM//Early secretome FAD linked oxidase, N-terminal + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin12g04650 227 Effector(V2)|Effector(V1) "Bcrip1, similar to yeast RIP1, Ubiquinol-cytochrome-c reductase; a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration; during import, Rip1p is first imported into the mitochondrial matrix where it is processed, acquires its Fe-S cluster, and is folded, then is translocated into the inner membrane by the action of a homo-oligomer of Bcs1p, and finally is delivered by Bcs1p to Complex III for assembly [Source:SGD;Acc:S000000750]" Bcin12g04660 566 "Bctcp1, similar to yeast TCP1, Alpha subunit of chaperonin-containing T-complex; complex mediates protein folding in the cytosol; involved in actin cytoskeleton maintenance; overexpression in neurons suppresses formation of pathogenic conformations of huntingtin protein [Source:SGD;Acc:S000002620]" Bcin12g04670 594 Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain + Proline-tRNA ligase, class IIa + Anticodon-binding + Proline-tRNA ligase, class IIa, archaeal-type + Aminoacyl-tRNA synthetase, class II + Proline-tRNA ligase, class II, C-terminal + Prolyl-tRNA synthetase, class II Bcin12g04680 1170 Bcpkc1, Protein kinase C Bcin12g04690 443 Acyl-CoA dehydrogenase, conserved site + Acyl-CoA oxidase/dehydrogenase, central domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase/oxidase, N-terminal Bcin12g04700 515 Major facilitator superfamily + Major facilitator superfamily domain Bcin12g04710 136 Translation initiation factor 1A (eIF-1A) + RNA-binding domain, S1, IF1 type + Nucleic acid-binding, OB-fold Bcin12g04720 441 CAZy : GT58 "Bcalg3, similar to yeast ALG3, Dolichol-P-Man dependent alpha(1-3) mannosyltransferase; involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins [Source:SGD;Acc:S000000178]" Bcin12g04730 1466 SNF2-related + Helicase, C-terminal + Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Helicase superfamily 1/2, ATP-binding domain + Zinc finger, RING-type, conserved site + Zinc finger, C3HC4 RING-type + P-loop containing nucleoside triphosphate hydrolase Bcin12g04740 316 CAZy : GH128 //SignalP-noTM Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Uncharacterised protein family, glycosyl hydrolase catalytic domain Bcin12g04750 546 Amidase + Amidase, conserved site + Amidase signature domain Bcin12g04760 324 PQ-loop repeat Bcin12g04770 333 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin12g04780 204 Effector(V2) Isochorismatase-like Bcin12g04790 353 Bcin12g04800 354 Bcin12g04810 302 Bcin12g04820 633 Protease Alpha/beta hydrolase fold-1 + Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal + Alpha/Beta hydrolase fold Bcin12g04830 318 NUDIX hydrolase domain + NUDIX hydrolase domain-like Bcin12g04840 91 Bcin12g04850 1186 Bcin12g04860 2246 Protease Aspartate carbamoyltransferase + Carbamoyl-phosphate synthase, small subunit N-terminal domain + Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain + Carbamoyl-phosphate synthetase, large subunit oligomerisation domain + Carbamoyl-phosphate synthase large subunit, CPSase domain + Aspartate/ornithine carbamoyltransferase + Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain + Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding + Carbamoyl-phosphate synthase, small subunit + Carbamoyl-phosphate synthase, large subunit + Methylglyoxal synthase-like domain + ATP-grasp fold + ATP-grasp fold, subdomain 1 + ATP-grasp fold, subdomain 2 + Pre-ATP-grasp domain + Glutamine amidotransferase + Class I glutamine amidotransferase-like + Metal-dependent hydrolase Bcin12g04870 541 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin12g04880 447 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g04890 736 Cys2His2 transcription factor + Fungal_trans Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin12g04900 450 yes Bckmo, kynurenine 3-monooxygenase Bcin12g04910 324 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin12g04920 292 Effector(V2) Calcineurin-like phosphoesterase domain, apaH type + Metallo-dependent phosphatase-like Bcin12g04930 221 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin12g04940 509 SM cluster NRPS1 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin12g04950 802 Zn2/Cys6 + fungal trans transcription factor//SM cluster NRPS1 Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin12g04960 221 SM cluster NRPS1//Effector(V2)|Effector(V1) NAD(P)-binding domain Bcin12g04970 424 SM cluster NRPS1 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g04980 1592 yes SM cluster NRPS1 (KE) Bcnrps1, Nonribosomal peptide synthetase Bcin12g04990 672 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin12g05000 277 "Bcaro7, similar to yeast ARO7, Chorismate mutase; catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis [Source:SGD;Acc:S000006264]" Bcin12g05010 299 Signaling pathway "Bcbcp1, similar to yeast BCP1, Essential protein involved in nuclear export of Mss4p; Mss4p is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport [Source:SGD;Acc:S000002769]" Bcin12g05020 652 SH3 domain Bcin12g05030 98 Bcpio7, Gene with a peak of expression during the Outset of colonization Bcin12g05040 1566 "Bcvps15, similar to yeast VPS15, Serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p; myristoylated; a fraction is localized, with Vps34p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery [Source:SGD;Acc:S000000301]" Bcin12g05050 248 Effector(V1) "Bclea1, similar to yeast LEA1, Component of U2 snRNP complex; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; putative homolog of human U2A' snRNP protein [Source:SGD;Acc:S000006134]" Bcin12g05060 289 CBF/NF-Y/archaeal histone transcription factor Transcription factor CBF/NF-Y/archaeal histone + Histone-fold Bcin12g05070 1250 AMP-dependent synthetase/ligase + Acyl carrier protein-like + Male sterility, NAD-binding + NAD(P)-binding domain Bcin12g05080 252 Effector(V1) RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin12g05090 261 Effector(V1) "Bcvma8, similar to yeast VMA8, Subunit D of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; plays a role in the coupling of proton transport and ATP hydrolysis; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits [Source:SGD;Acc:S000000777]" Bcin12g05100 838 "Bcsyf1, similar to yeast SYF1, Member of the NineTeen Complex (NTC); that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; null mutant has splicing defect and arrests in G2/M; relocalizes to the cytosol in response to hypoxia; homologs in human and C. elegans [Source:SGD;Acc:S000002824]" Bcin12g05110 154 Effector(V1) Bcin12g05120 831 Protease//SignalP-noTM Aspartic peptidase + Aspartic peptidase domain + Peptidase family A1 domain Bcin12g05130 816 SignalP-noTM Bcin12g05140 1167 F-box domain + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + Proteasome subunit Rpn10 Bcin12g05150 415 "Bcppx1, similar to yeast PPX1, Exopolyphosphatase; hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix [Source:SGD;Acc:S000001244]" Bcin12g05160 128 Effector(V2)|Effector(V1) Glucose-methanol-choline oxidoreductase, N-terminal + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g05170 522 Major facilitator superfamily + Major facilitator superfamily domain Bcin12g05180 254 Bcin12g05190 305 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin12g05200 983 AAA+ ATPase domain + ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin12g05210 341 Early secretome "Bcmdh1, similar to yeast MDH1, Mitochondrial malate dehydrogenase; catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated [Source:SGD;Acc:S000001568]" Bcin12g05220 474 CAZy : GH5PCW/FCW Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin12g05230 1509 UBA-like + Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote Bcin12g05240 1512 Dynamin superfamily + P-loop containing nucleoside triphosphate hydrolase Bcin12g05250 247 Effector(V2)|Effector(V1) Bcin12g05260 449 Bcin12g05270 212 Heterokaryon incompatibility Bcin12g05280 526 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin12g05290 620 "Bcgln4, similar to yeast GLN4, Glutamine tRNA synthetase; monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Gln); N-terminal domain proposed to be involved in enzyme-tRNA interactions [Source:SGD;Acc:S000005694]" Bcin12g05300 290 Macro domain Bcin12g05310 430 Ribosomal RNA large subunit methyltransferase F-like + S-adenosyl-L-methionine-dependent methyltransferase Bcin12g05320 360 Bcin12g05330 207 Effector(V2)|Effector(V1) Glycolipid transfer protein domain Bcin12g05340 368 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin12g05350 270 Effector(V2)|Effector(V1) Bcin12g05360 1779 yes BcCHSVI, Class VI chitin synthase Bcin12g05370 1876 yes BcCHSV, Class V chitin synthase Bcin12g05380 206 Effector(V1) Bcin12g05390 122 Bcin12g05400 230 Bcin12g05410 327 "Bcesf2, similar to yeast ESF2, Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome [Source:SGD;Acc:S000005337]" Bcin12g05420 467 Aldehyde dehydrogenase domain + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain + Aldehyde dehydrogenase, C-terminal + Aldehyde dehydrogenase, glutamic acid active site Bcin12g05430 118 Effector(V2)|Effector(V1) Bcin12g05440 852 Bcin12g05450 290 Bcin12g05460 598 Protease Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin12g05470 583 Sodium/calcium exchanger membrane region Bcin12g05480 444 Sensitivity To Red Light Reduced-like, SRR1 Bcin12g05490 447 Sensitivity To Red Light Reduced-like, SRR1 Bcin12g05500 273 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin12g05510 570 Amino acid/polyamine transporter I + Amino acid permease, conserved site Bcin12g05520 181 GNAT domain + Acyl-CoA N-acyltransferase Bcin12g05530 228 Effector(V2) HAD-superfamily phosphatase, subfamily IIIC + Magnesium-dependent phosphatase-1, eukaryotic/arcaheal type + HAD-like domain Bcin12g05540 1249 DNA repair protein Rad4 + Rad4/PNGase transglutaminase-like fold + Rad4 beta-hairpin domain 1 + Rad4 beta-hairpin domain 2 + Rad4 beta-hairpin domain 3 Bcin12g05550 422 Aspartate/other aminotransferase + Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase Bcin12g05560 350 Target SNARE coiled-coil domain + SNARE-complex protein Syntaxin-18 N-terminal Bcin12g05570 633 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin12g05580 400 AdipoR/Haemolysin-III-related Bcin12g05590 572 Bcin12g05600 618 Bcin12g05610 610 Transcription-silencing protein Clr2 + Cryptic loci regulator 2, N-terminal Bcin12g05620 387 SignalP-noTM Pectate lyase/Amb allergen + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin12g05630 397 Zinc finger, FYVE/PHD-type Bcin12g05640 382 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin12g05650 762 Bcin12g05660 313 Kynurenine formamidase, vertebrates/fungi-type + Alpha/Beta hydrolase fold Bcin12g05670 430 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g05680 715 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin12g05690 240 Effector(V1) Bcgst20, Glutathione S-transferase Bcin12g05700 387 Early secretome Six-hairpin glycosidase-like + Glycosyl hydrolase, family 88 + Six-hairpin glycosidase Bcin12g05710 271 "Bcmet8, similar to yeast MET8, Bifunctional dehydrogenase and ferrochelatase; involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis [Source:SGD;Acc:S000000417]" Bcin12g05720 665 Cys2His2 transcription factor "Bcpep7, similar to yeast PEP7, Adaptor protein involved in vesicle-mediated vacuolar protein sorting; multivalent adaptor protein; facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion, which are essential for targeting of vesicles to the endosome; required for vacuole inheritance [Source:SGD;Acc:S000002731]" Bcin12g05730 463 "Bclat1, similar to yeast LAT1, Dihydrolipoamide acetyltransferase component (E2) of the PDC; the pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA [Source:SGD;Acc:S000005015]" Bcin12g05740 1816 "Bcsec7, similar to yeast SEC7, Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors; involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles [Source:SGD;Acc:S000002577]" Bcin12g05750 1071 Zn2/Cys6 transcription factor Bcin12g05760 212 yes Signaling pathway Bcras1, Ras-like GTPase Bcin12g05770 329 MoaB/Mog domain Bcin12g05780 560 CRAL-TRIO domain + CRAL/TRIO, N-terminal domain Bcin12g05790 382 PI31 proteasome regulator + Fbxo7/PI31 domain Bcin12g05800 750 Bcin12g05810 444 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g05820 362 Bcin12g05830 632 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin12g05840 697 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin12g05850 317 Effector(V2) Bcin12g05860 358 SignalP-noTM Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin12g05870 510 Molybdenum cofactor sulfurase, C-terminal + MOSC, N-terminal beta barrel Bcin12g05880 1581 Dbl homology (DH) domain Bcin12g05885 90 Effector(V2)|Effector(V1) Bcin12g05890 163 Sister chromatid cohesion protein Dcc1 Bcin12g05900 248 Bcin12g05910 380 Bcin12g05920 606 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin12g05930 269 Protein of unknown function DUF1275 Bcin12g05940 377 Beta-lactamase-like Bcin12g05950 453 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin12g05960 142 Effector(V2)|Effector(V1) Domain of unknown function DUF202 Bcin12g05970 102 Effector(V2)|Effector(V1) Bcin12g05980 1217 Bcin12g05985 386 Acyl-CoA N-acyltransferase Bcin12g05990 295 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa DNA-binding HORMA Bcin12g06000 1048 "Bckap114, similar to yeast KAP114, Karyopherin, responsible for nuclear import of specific proteins; cargoes include Spt15p, Sua7p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear; function is regulated by sumoylation; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003210]" Bcin12g06010 562 Protein of unknown function DUF3468 Bcin12g06020 985 Transporter P-type ATPase + Cation-transporting P-type ATPase, N-terminal + P-type ATPase, subfamily IIIA + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, transmembrane domain + P-type ATPase, cytoplasmic domain N Bcin12g06030 186 Bcin12g06040 204 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Cytochrome P450 Bcin12g06050 1217 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin12g06060 510 Major facilitator superfamily + Major facilitator superfamily domain Bcin12g06070 308 Protein of unknown function DUF924 + Tetratricopeptide-like helical domain Bcin12g06080 111 Effector(V1) Bcin12g06090 320 Bcin12g06100 303 SM 0 Protein of unknown function DUF3328 Bcin12g06110 102 SignalP-noTM//Effector(V2)|Effector(V1) Bcin12g06120 295 CAZy : GH131 //SignalP-noTM//Early secretome Bcin12g06130 252 Protease Peptidase C12, ubiquitin carboxyl-terminal hydrolase Bcin12g06140 404 SignalP-noTM "Bcyke4, similar to yeast YKE4, Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family [Source:SGD;Acc:S000001285]" Bcin12g06150 343 SignalP-TM//Effector(V2)|Effector(V1) Bcin12g06160 907 Bcin12g06170 300 Bcin12g06180 371 Nitrilase/cyanide hydratase, conserved site + Carbon-nitrogen hydrolase Bcin12g06190 1326 Bcin12g06200 1148 Bcin12g06210 612 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin12g06220 356 TAP42-like protein Bcin12g06230 1968 yes BcdcL1, Dicer-like gene Bcin12g06240 467 "Bcpex12, similar to yeast PEX12, C3HC4-type RING-finger peroxin and E3 ubiquitin ligase; required for peroxisome biogenesis and peroxisomal matrix protein import; forms translocation subcomplex with Pex2p and Pex10p; mutations in human homolog cause peroxisomal disorder [Source:SGD;Acc:S000004628]" Bcin12g06250 416 Bcin12g06260 285 Bcin12g06270 197 Bcin12g06280 723 SignalP-TM "Bctmn3, similar to yeast TMN3, Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn2p; member of Transmembrane Nine family with 9 transmembrane segments; localizes to Golgi; induced by 8-methoxypsoralen plus UVA irradiation [Source:SGD;Acc:S000000915]" Bcin12g06290 206 Effector(V2)|Effector(V1) Bcin12g06300 354 yes Protease//SignalP-noTM Bcmp, metallopeptidase Bcin12g06310 205 Effector(V1) Bcin12g06320 249 "Bcpdx3, similar to yeast PDX3, Pyridoxine (pyridoxamine) phosphate oxidase; has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism [Source:SGD;Acc:S000000239]" Bcin12g06330 521 SignalP-noTM//Early secretome Yeast PIR protein repeat Bcin12g06340 116 Effector(V2) Bcin12g06350 599 Transporter Bchex6, Similar to MFS sugar transporter Bcin12g06360 496 Protease//SignalP-noTM//Early secretome Carboxylesterase, type B + Carboxylesterase type B, conserved site + Alpha/Beta hydrolase fold Bcin12g06370 526 yes SM cluster BOT Bcbot4, Cytochrome P450 monooxygenase, in botrydial biosynthesis gene cluster Bcin12g06380 510 yes SM cluster BOT Bcbot1, Benzoate 4-monooxygenase cytochrome p450, in botrydial biosynthesis gene cluster Bcin12g06390 399 yes SM cluster BOT (KE) Bcbot2,Bcstc1, Sesquiterpen cyclase, in botrydial biosynthesis gene cluster Bcin12g06400 567 yes SM cluster BOT Bcbot3, Cytochrome P450 monooxygenase, in botrydial biosynthesis gene cluster, CalciNeurine-Dependant (CND) gene, gene with a peak of expression during the Outset of colonization Bcin12g06410 545 SM cluster BOT//SignalP-noTM Bcbot5, Acetyl transferase, in botrydial biosynthesis gene cluster Bcin12g06420 484 yes Zn2/Cys6 transcription factor//SM cluster BOT BcBot6, transcription_factor_Cys6 Bcin12g06430 317 SM cluster BOT BcBot7, Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin12g06440 462 yes BcMettl4, 6mA methyltransferase Bcin12g06450 197 "Bcmrp20, similar to yeast MRP20, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000002813]" Bcin12g06460 252 Protease//Effector(V2)|Effector(V1) Dienelactone hydrolase + Alpha/Beta hydrolase fold Bcin12g06470 1059 Hamartin + Armadillo-like helical + Armadillo-type fold Bcin12g06480 420 Transporter "Bcleu5, similar to yeast LEU5, Mitochondrial carrier protein; involved in the accumulation of CoA in the mitochondrial matrix; homolog of human Graves disease protein; does not encode an isozyme of Leu4p, as first hypothesized [Source:SGD;Acc:S000001044]" Bcin12g06490 617 Major facilitator superfamily domain Bcin12g06500 401 Protease Peptidase C12, ubiquitin carboxyl-terminal hydrolase Bcin12g06510 331 CAZy : GH16FCW //SignalP-noTM Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin12g06520 494 Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin12g06530 1314 Bcin12g06540 101 Effector(V1) "Bcatp17, similar to yeast ATP17, Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis [Source:SGD;Acc:S000002785]" Bcin12g06550 219 Effector(V2)|Effector(V1) NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial Bcin12g06560 1220 "Bcprp2, similar to yeast PRP2, RNA-dependent DExD/H-box ATPase; required for activation of spliceosome before first transesterification step in RNA splicing; implicated in rearranging and proofreading snRNA structure in catalytic activation of spliceosome; ortholog of human protein DHX16 [Source:SGD;Acc:S000005294]" Bcin12g06570 54 Effector(V2)|Effector(V1) Bcin12g06580 141 Effector(V2)|Effector(V1) Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin12g06590 463 CAZy : GH5PCW/FCW //SignalP-noTM Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin12g06600 555 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin12g06610 383 Bcin12g06620 61 Bcin12g06630 355 CAZy : GH45PCW cellulose//SignalP-noTM//Early secretome Glycoside hydrolase, family 45 + RlpA-like double-psi beta-barrel domain Bcin12g06640 504 "Bcesa1, similar to yeast ESA1, Catalytic subunit of the histone acetyltransferase complex (NuA4); acetylates four conserved internal lysines of histone H4 N-terminal tail and can acetylate histone H2A; master regulator of cellular acetylation balance; required for cell cycle progression and transcriptional silencing at the rDNA locus and regulation of autophagy; human ortholog TIP60/KAT5 is implicated in cancer and other diseases [Source:SGD;Acc:S000005770]" Bcin12g06650 333 "Bcrex4, similar to yeast REX4, Putative RNA exonuclease; possibly involved in pre-rRNA processing and ribosome assembly [Source:SGD;Acc:S000005440]" Bcin12g06660 480 S-adenosyl-L-methionine-dependent methyltransferase Bcin12g06670 170 Ribonuclease H2, subunit C Bcin12g06680 284 Protein of unknown function DUF4385 Bcin12g06690 286 NAD(P)-binding domain + Ergot alkaloid biosynthesis protein Bcin12g06700 128 SignalP-noTM//Effector(V2)|Effector(V1) Bcin12g06710 409 Protease//SignalP-noTM ArgE/DapE/ACY1/CPG2/YscS, conserved site + Peptidase M20 + Peptidase M20, dimerisation domain Bcin12g06720 500 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin12g06730 453 Phospholipase D/Transphosphatidylase + Phospholipase D-like domain Bcin12g06740 951 "Bcmcm6, similar to yeast MCM6, Protein involved in DNA replication; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex; forms a subcomplex with Mcm4p and Mcm7p [Source:SGD;Acc:S000003169]" Bcin12g06750 621 Proton-dependent oligopeptide transporter family + Major facilitator superfamily domain Bcin12g06760 84 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin12g06770 357 SignalP-noTM Six-bladed beta-propeller, TolB-like Bcin12g06780 456 Bcin12g06790 322 Bcin12g06800 337 Bcin12g06810 532 Bcin13g00010 518 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin13g00020 180 Effector(V2)|Effector(V1) GNAT domain + Acyl-CoA N-acyltransferase Bcin13g00030 248 Transcriptional regulator PAI 2-type + FMN-binding split barrel Bcin13g00040 124 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Gamma-crystallin-related Bcin13g00050 375 SignalP-noTM Bcin13g00060 778 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin13g00070 397 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin13g00080 413 SignalP-noTM Ureohydrolase + Ureohydrolase, manganese-binding site + Ureohydrolase domain Bcin13g00090 194 yes Effector(V2)|Effector(V1)//Signaling pathway Bccdc42, Cell division control protein 42 Bcin13g00100 206 Effector(V2)|Effector(V1) Bcin13g00110 607 SignalP-noTM Bclcc12, Laccase/ Multicopper oxidase Bcin13g00120 331 Bcin13g00130 309 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin13g00140 358 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin13g00160 206 Effector(V2)|Effector(V1) Crotonase superfamily + ClpP/crotonase-like domain Bcin13g00170 201 Effector(V2) Bcin13g00180 258 GPR1/FUN34/yaaH Bcin13g00190 134 Effector(V1) Bcin13g00200 536 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin13g00210 633 Phox homologous domain Bcin13g00220 823 "Bcmrn1, similar to yeast MRN1, RNA-binding protein that may be involved in translational regulation; binds specific categories of mRNAs, including those that contain upstream open reading frames (uORFs) and internal ribosome entry sites (IRES); interacts genetically with chromatin remodelers and splicing factors, linking chromatin state, splicing and as a result mRNA maturation [Source:SGD;Acc:S000006105]" Bcin13g00230 586 "Bcded81, similar to yeast DED81, Cytosolic asparaginyl-tRNA synthetase; required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA [Source:SGD;Acc:S000001061]" Bcin13g00240 923 "Bccdc9, similar to yeast CDC9, DNA ligase found in the nucleus and mitochondria; an essential enzyme that joins Okazaki fragments during DNA replication; also acts in ribonucleotide excision repair, base excision repair, and recombination, [Source:SGD;Acc:S000002323]" Bcin13g00250 527 Transporter "Bcant1, similar to yeast ANT1, Peroxisomal adenine nucleotide transporter; involved in beta-oxidation of medium-chain fatty acid; required for peroxisome proliferation [Source:SGD;Acc:S000006332]" Bcin13g00260 366 Bcin13g00270 364 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Nitric oxide synthase-interacting + Zinc finger, RING-type, conserved site + RING-type zinc-finger, LisH dimerisation motif + Nitric oxide synthase-interacting protein, zinc-finger Bcin13g00280 481 Fatty acid desaturase, type 1 Bcin13g00290 478 Bcin13g00300 160 SignalP-noTM Bcin13g00310 729 Cys2His2 transcription factor Zinc finger, C2H2 Bcin13g00320 105 Bcin13g00330 114 Bcin13g00340 688 Heterokaryon incompatibility Bcin13g00350 553 Bcin13g00360 133 Bcin13g00370 756 Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Tetratricopeptide repeat + Clr5 domain Bcin13g00380 142 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Bcin13g00390 389 "Bcceg1, similar to yeast CEG1, Guanylyltransferase involved in mRNA 5' capping; subunit of the mRNA capping enzyme, which is a heterotetramer composed of two molecules of Ceg1p and a homodimer of Cet1p, the mRNA 5?-triphosphatase subunit; nuclear import of Ceg1p requires interaction with Cet1p; mammalian capping enzyme is a single bifunctional polypeptide [Source:SGD;Acc:S000003098]" Bcin13g00400 829 Tetrapeptide transporter, OPT1/isp4 + Oligopeptide transporter, OPT superfamily Bcin13g00410 232 Effector(V2) Bcin13g00420 65 Effector(V2)|Effector(V1) Bcin13g00430 405 Bcin13g00440 221 "Bctim23, similar to yeast TIM23, Essential component of the TIM23 complex; involved in protein import into mitochondrial matrix and inner membrane; with Tim17p, contributes to architecture and function of the import channel; TIM23 complex is short for the translocase of the inner mitochondrial membrane [Source:SGD;Acc:S000005300]" Bcin13g00450 1580 Armadillo-like helical + Armadillo-type fold + Domain of unknown function DUF2428, death-receptor-like Bcin13g00460 392 "Bctaz1, similar to yeast TAZ1, Lyso-phosphatidylcholine acyltransferase; required for normal phospholipid content of mitochondrial membranes; major determinant of the final acyl chain composition of the mitochondrial-specific phospholipid cardiolipin; mutations in human ortholog tafazzin cause Barth syndrome, a rare X-linked disease characterized by skeletal and cardiomyopathy and bouts of cyclic neutropenia [Source:SGD;Acc:S000006344]" Bcin13g00470 660 SignalP-noTM Bcin13g00480 1708 "Bcpds5, similar to yeast PDS5, Cohesion maintenance factor; involved in sister chromatid condensation and cohesion; colocalizes with cohesin on chromosomes; performs its cohesin maintenance function in pre-anaphase cells by protecting the integrity of the cohesion complex; also required during meiosis; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000004681]" Bcin13g00490 603 Ribonuclease CAF1 + Ribonuclease H-like domain Bcin13g00500 463 Bcin13g00510 484 Major facilitator superfamily + Major facilitator superfamily domain Bcin13g00520 420 "Bcsgf73, similar to yeast SGF73, SAGA complex subunit; has a role in anchoring the deubiquitination module into SAGA and SLIK complexes; involved in preinitiation complex assembly at promoters; relocalizes to the cytosol in response to hypoxia; human ortholog ataxin-7 is associated with spinocerebellar ataxia diseases; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay [Source:SGD;Acc:S000003034]" Bcin13g00530 316 NmrA-like domain + NAD(P)-binding domain Bcin13g00540 723 "Bcsnf5, similar to yeast SNF5, Subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p; relocates to the cytosol under hypoxic conditions [Source:SGD;Acc:S000000493]" Bcin13g00550 401 Protease "Bcarx1, similar to yeast ARX1, Nuclear export factor for the ribosomal pre-60S subunit; shuttling factor which directly binds FG rich nucleoporins and facilities translocation through the nuclear pore complex; interacts directly with Alb1p; responsible for Tif6p recycling defects in the absence of Rei1; associated with the ribosomal export complex [Source:SGD;Acc:S000002508]" Bcin13g00560 1270 "Bcrco1, similar to yeast RCO1, Essential component of the Rpd3S histone deacetylase complex; interacts with Eaf3p [Source:SGD;Acc:S000004680]" Bcin13g00570 463 Major facilitator superfamily + Major facilitator superfamily domain Bcin13g00580 469 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin13g00590 552 Amidase + Amidase signature domain Bcin13g00600 193 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Bcin13g00610 75 Bcin13g00620 1160 RNA recognition motif domain + Pumilio RNA-binding repeat + Armadillo-like helical + Nucleotide-binding alpha-beta plait domain + Armadillo-type fold + Pumilio homology domain Bcin13g00630 701 YL1 nuclear + YL1 nuclear, C-terminal Bcin13g00640 217 Bcin13g00650 176 Haemerythrin/HHE cation-binding motif Bcin13g00660 318 NmrA-like domain + NAD(P)-binding domain Bcin13g00670 736 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin13g00680 1076 WSTF/Acf1/Cbp146 + DDT domain superfamily + WHIM2 domain + WHIM1 domain Bcin13g00690 504 CAZy : GT57 Glycosyl transferase, ALG6/ALG8 Bcin13g00700 449 Legume-like lectin + Concanavalin A-like lectin/glucanase domain Bcin13g00710 1439 yes Transporter BcatrB, ABC transporter Bcin13g00720 435 Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin13g00730 480 Major facilitator superfamily + Major facilitator superfamily domain Bcin13g00740 202 Effector(V2)|Effector(V1) Bcin13g00750 108 Effector(V2)|Effector(V1) "Bcrds3, similar to yeast RDS3, Component of the SF3b subcomplex of the U2 snRNP; zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance [Source:SGD;Acc:S000006298]" Bcin13g00760 309 Pinin/SDK/MemA protein Bcin13g00770 336 Protease Alpha/beta hydrolase fold-1 + Epoxide hydrolase-like + Alpha/Beta hydrolase fold Bcin13g00780 683 Zinc finger, RING-type + Zinc finger, PHD-type + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, PHD-type, conserved site + Zinc finger, PHD-finger + Zinc finger, RING-H2-type Bcin13g00790 349 "Bcmrpl17, similar to yeast MRPL17, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000005196]" Bcin13g00810 416 Bcdao3, D-amino acid oxidase Bcin13g00820 443 Bcin13g00830 92 Effector(V1) Ribosomal protein L37ae + Ribosomal protein L37ae/L37e + Zinc-binding ribosomal protein Bcin13g00840 412 Saccharopine dehydrogenase / Homospermidine synthase + NAD(P)-binding domain Bcin13g00850 162 Bcin13g00860 212 Effector(V1) Bcin13g00870 1102 Transporter P-type ATPase + Cation-transporting P-type ATPase, N-terminal + Cation-transporting P-type ATPase, C-terminal + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, transmembrane domain + P-type ATPase, cytoplasmic domain N Bcin13g00880 165 Bcin13g00890 103 Effector(V1) Histone H4 + TATA box binding protein associated factor (TAF) + Histone-fold + Histone H4, conserved site Bcin13g00900 163 Effector(V2)|Effector(V1) "Bctrs20, similar to yeast TRS20, Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factors for the GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII); mutation of conserved residues leads to defects in endocytic recycling and a block in sporulation/meiosis; mutations in the human homolog cause the spondyloepiphyseal dysplasia [Source:SGD;Acc:S000000458]" Bcin13g00910 110 "Bcmrpl31, similar to yeast MRPL31, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000001621]" Bcin13g00920 181 Effector(V1) "Bccbc2, similar to yeast CBC2, Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif [Source:SGD;Acc:S000006099]" Bcin13g00930 897 WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin13g00940 739 Zinc finger, CCCH-type Bcin13g00950 377 Bcin13g00960 670 SignalP-TM//Early secretome "Bckar2, similar to yeast KAR2, ATPase involved in protein import into the ER; also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p [Source:SGD;Acc:S000003571]" Bcin13g00970 547 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin13g00980 782 "Bchbs1, similar to yeast HBS1, GTPase with similarity to translation release factors; together with binding partner Dom34p, facilitates ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, particularly in 3' UTRs; genetically implicated in mRNA no-go decay; HBS1 has a paralog, SKI7, that arose from the whole genome duplication [Source:SGD;Acc:S000001792]" Bcin13g00990 728 "Bcvps27, similar to yeast VPS27, Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p) [Source:SGD;Acc:S000005289]" Bcin13g01000 1097 Protease Peptidase C19, ubiquitin carboxyl-terminal hydrolase + Rhodanese-like domain + Ubiquitin specific protease domain Bcin13g01010 249 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin13g01020 108 Bcin13g01030 197 Effector(V1) Protein of unknown function DUF4452 Bcin13g01040 306 "Bcssn8, similar to yeast SSN8, Cyclin-like component of the RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; forms a kinase-cyclin pair in the RNAPII holoenzyme with Ssn3p; required for both entry into and execution of the meiotic program; involved in glucose repression and telomere maintenance; cyclin homolog 35% identical to human cyclin C [Source:SGD;Acc:S000004970]" Bcin13g01050 615 Transporter "Bcsal1, similar to yeast SAL1, ADP/ATP transporter; member of the Ca2+-binding subfamily of mitochondrial carriers, with two EF-hand motifs; transport activity of either Sal1p or Pet9p is critical for viability; polymorphic in different S. cerevisiae strains [Source:SGD;Acc:S000005027]" Bcin13g01060 281 Target SNARE coiled-coil domain Bcin13g01070 503 Zinc finger, TRAF-type + Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site Bcin13g01080 330 Vacuolar protein sorting-associated protein 62 + Aerolysin-like toxin, beta complex domain Bcin13g01090 847 Transporter ABC transporter-like + AAA+ ATPase domain + ABC-2 type transporter + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin13g01100 469 Bcin13g01110 375 RTA-like protein Bcin13g01120 345 Bcin13g01130 238 SignalP-noTM Bcin13g01140 279 SM 0 Protein of unknown function DUF3328 Bcin13g01150 397 SignalP-noTM Bcin13g01160 664 Two pore domain potassium channel + Two pore domain potassium channel domain Bcin13g01170 426 Bcin13g01180 377 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin13g01190 315 RTA-like protein Bcin13g01200 86 Effector(V2)|Effector(V1) Bcin13g01210 238 Bcin13g01220 181 Chromo/chromo shadow domain + Chromo domain-like Bcin13g01230 85 Effector(V2)|Effector(V1) Bcin13g01240 358 Bcin13g01250 146 Effector(V2)|Effector(V1) YjgF/Yer057p/UK114 family + Endoribonuclease L-PSP/chorismate mutase-like Bcin13g01260 732 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin13g01270 226 Effector(V2)|Effector(V1)//Signaling pathway Bcvvd1, Vivid-like, potential blue light sensor Bcin13g01280 60 Ribosomal protein L33 + Zinc-binding ribosomal protein Bcin13g01290 1705 Bcin13g01300 245 SignalP-noTM Bcin13g01310 643 "Bcenp2, similar to yeast ENP2, Component of the SSU; required for pre-18S rRNA processing, biogenesis of the small ribosomal subunit; interacts with U3 snoRNA, Mpp10p and Bfr2p; contains WD repeats, and has homology to Spb1p [Source:SGD;Acc:S000003377]" Bcin13g01320 1531 Mediator complex, subunit Med13 + Mediator complex, subunit Med13, N-terminal, metazoa/fungi Bcin13g01330 308 "Bcmeu1, similar to yeast MEU1, Methylthioadenosine phosphorylase (MTAP); catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression [Source:SGD;Acc:S000004007]" Bcin13g01340 1486 "Bcmot2, similar to yeast MOT2, Ubiquitin-protein ligase subunit of the CCR4-NOT complex; with Ubc4p, ubiquitinates nascent polypeptide-associated complex subunits and histone demethyase Jhd2p; CCR4-NOT has roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication [Source:SGD;Acc:S000000870]" Bcin13g01350 292 NADH:ubiquinone oxidoreductase, 30kDa subunit + NADH dehydrogenase, subunit C + NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site Bcin13g01360 513 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin13g01370 597 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin13g01380 536 Protease Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin13g01390 1914 "Bcufd4, similar to yeast UFD4, Ubiquitin-protein ligase (E3); interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000001493]" Bcin13g01400 286 Cytidyltransferase-like domain + Probable nicotinate-nucleotide adenylyltransferase + Rossmann-like alpha/beta/alpha sandwich fold Bcin13g01410 1278 SignalP-noTM "Bcncr1, similar to yeast NCR1, Vacuolar membrane protein; transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; cells lacking Ncr1p exhibit high levels of long chain bases (LCB), similar to the accumulation of high amounts of lipids observed in patients with Neimann-Pick C, a disease caused by loss-of-function mutations in NPC1, the functional ortholog of Ncr1p [Source:SGD;Acc:S000005927]" Bcin13g01420 558 Smr protein/MutS2 C-terminal + Domain of unknown function DUF1771 Bcin13g01430 457 Dehydrogenase, E1 component + Thiamin diphosphate-binding fold Bcin13g01440 321 "Bccoq5, similar to yeast COQ5, 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase; involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes [Source:SGD;Acc:S000004578]" Bcin13g01450 711 Domain of unknown function DUF2433 + Metallo-dependent phosphatase-like Bcin13g01460 281 BTB/POZ-like + BTB/POZ fold Bcin13g01470 586 SignalP-noTM FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin13g01480 256 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin13g01490 550 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin13g01500 301 Protease Putative lysophospholipase + Alpha/Beta hydrolase fold Bcin13g01510 2417 SM cluster PKS10 (KE) Bcpks10, Polyketide synthase Bcin13g01520 382 Ankyrin repeat + Ankyrin repeat-containing domain Bcin13g01530 367 Bcin13g01540 629 Bcin13g01550 119 Effector(V2)|Effector(V1) Bcin13g01560 309 NADPH-dependent FMN reductase-like + Arsenate resistance ArsH + Flavoprotein-like Bcin13g01570 499 "Bczpr1, similar to yeast ZPR1, Essential protein with two zinc fingers; present in the nucleus of growing cells but relocates to the cytoplasm in starved cells via a process mediated by Cpr1p; binds to translation elongation factor eEF-1 (Tef1p); relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003443]" Bcin13g01580 195 RNAse P, Rpr2/Rpp21 subunit Bcin13g01590 584 "Bcdbr1, similar to yeast DBR1, RNA lariat debranching enzyme; catalyzes debranching of lariat introns formed during pre-mRNA splicing; required for efficient Ty1 transposition; knockdown of human homolog Dbr1 rescues toxicity of RNA-binding proteins TDP-43 and FUS which are implicated in amyotrophic lateral sclerosis (ALS), suggests potential therapeutic target for ALS and related TDP-43 proteinopathies [Source:SGD;Acc:S000001632]" Bcin13g01600 1159 "Bcgde1, similar to yeast GDE1, Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes [Source:SGD;Acc:S000006031]" Bcin13g01610 486 Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin13g01620 494 "Bcabd1, similar to yeast ABD1, Methyltransferase; catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN terminus of capped mRNA; nuclear protein that relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000000440]" Bcin13g01630 489 "Bcrpn7, similar to yeast RPN7, Essential non-ATPase regulatory subunit of the 26S proteasome; similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits [Source:SGD;Acc:S000006312]" Bcin13g01640 627 "Bcgem1, similar to yeast GEM1, Outer mitochondrial membrane GTPase, subunit of the ERMES complex; potential regulatory subunit of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; ortholog of metazoan Miro GTPases [Source:SGD;Acc:S000000046]" Bcin13g01650 632 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin13g01660 372 GNAT domain + Bromodomain + Acyl-CoA N-acyltransferase Bcin13g01670 504 Bcin13g01680 450 "Bcsen54, similar to yeast SEN54, Subunit of the tRNA splicing endonuclease; tRNA splicing endonuclease is composed of Sen2p, Sen15p, Sen34p, and Sen54p [Source:SGD;Acc:S000006004]" Bcin13g01690 50 Effector(V1) Bcin13g01700 51 Bcin13g01710 424 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin13g01720 467 Baculoviral inhibition of apoptosis protein repeat + Zinc finger, C3HC-like + Nuclear-interacting partner of ALK/Rsm1-like Bcin13g01730 418 "Bcmet22, similar to yeast MET22, Bisphosphate-3'-nucleotidase; involved in salt tolerance and methionine biogenesis; dephosphorylates 3'-phosphoadenosine-5'-phosphate and 3'-phosphoadenosine-5'-phosphosulfate, intermediates of the sulfate assimilation pathway [Source:SGD;Acc:S000005425]" Bcin13g01740 250 "Bcmrpl6, similar to yeast MRPL6, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000001190]" Bcin13g01750 515 SignalP-noTM Nuclear fusion protein, KAR5 Bcin13g01760 1519 FAM184 family Bcin13g01770 396 SignalP-noTM Bcin13g01780 65 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin13g01790 452 Bcin13g01800 290 Bcin13g01810 118 DASH complex subunit Dad1 Bcin13g01820 235 Effector(V2)|Effector(V1) Small GTPase superfamily + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin13g01830 580 Phosphatidic acid phosphatase type 2/haloperoxidase Bcin13g01840 171 Effector(V2)|Effector(V1) Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site + Cyclophilin-type peptidyl-prolyl cis-trans isomerase + Cyclophilin-like domain Bcin13g01850 400 Arrestin C-terminal-like domain + Immunoglobulin E-set Bcin13g01860 641 Bcin13g01870 433 Transporter Protein kinase domain + Tyrosine-protein kinase, active site + Protein kinase-like domain Bcin13g01880 479 Transporter "Bcfen2, similar to yeast FEN2, Plasma membrane H+-pantothenate symporter; confers sensitivity to the antifungal agent fenpropimorph; relocalizes from vacuole to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000623]" Bcin13g01890 196 Effector(V2)|Effector(V1) Bcin13g01900 545 Cytochrome b5-like heme/steroid binding domain + Fatty acid desaturase, type 1 + Fatty acid desaturase Bcin13g01910 1306 Bromo adjacent homology (BAH) domain + C-5 cytosine methyltransferase + DNA methylase, C-5 cytosine-specific, active site + S-adenosyl-L-methionine-dependent methyltransferase Bcin13g01920 138 Effector(V2)|Effector(V1) Bcin13g01930 998 "Bcemp65, similar to yeast EMP65, ER membrane protein of unknown function; forms an ER-membrane associated protein complex with Slp1p; identified along with SLP1 in a screen for mutants defective in the unfolded protein response (UPR); proposed to function in the folding of integral membrane proteins; interacts genetically with MPS1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000000942]" Bcin13g01940 385 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin13g01950 466 Zinc finger, RING/FYVE/PHD-type + Zinc finger, RING-type, conserved site + E3 ubiquitin ligase RBR family Bcin13g01960 380 Protein kinase domain + Protein kinase-like domain Bcin13g01970 599 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain + FMN-binding split barrel + Ferredoxin reductase-type FAD-binding domain + Riboflavin synthase-like beta-barrel Bcin13g01980 409 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin13g01990 461 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin13g02000 539 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin13g02010 240 SignalP-noTM Cupredoxin Bcin13g02020 332 Bcin13g02030 410 "Bccyc2, similar to yeast CYC2, Mitochondrial peripheral inner membrane protein; contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p) [Source:SGD;Acc:S000005563]" Bcin13g02040 172 Effector(V2)|Effector(V1) Bcin13g02050 623 Flavoprotein Bcin13g02060 276 Effector(V2) Protein kinase-like domain Bcin13g02070 806 Bcin13g02080 419 Bcin13g02090 229 SignalP-noTM//Effector(V2) Bcin13g02100 516 CAZy : GH7,CBM1PCW cellulose//SignalP-noTM//Early secretome Cellulose-binding domain, fungal + Glycoside hydrolase, family 7 + Concanavalin A-like lectin/glucanase domain Bcin13g02110 285 SM cluster CHS1 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin13g02120 500 SM cluster CHS1 "Bcbud22, similar to yeast BUD22, Protein required for rRNA maturation and ribosomal subunit biogenesis; required for 18S rRNA maturation; also required for small ribosomal subunit biogenesis; cosediments with pre-ribosomal particles; mutation decreases efficiency of +1 Ty1 frameshifting and transposition, and affects budding pattern [Source:SGD;Acc:S000004616]" Bcin13g02130 499 SM cluster CHS1 (KE) Bcchs1, Chalcones ynthase Bcin13g02140 131 Effector(V1) Bcin13g02150 355 Protein of unknown function DUF3468 Bcin13g02160 1125 Ankyrin repeat + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase + Fungal N-terminal domain of STAND protein Bcin13g02170 511 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin13g02180 343 Bcin13g02190 878 Bcin13g02200 132 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin13g02210 139 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1)//Early secretome Bcin13g02220 251 Effector(V2)|Effector(V1) NAD(P)-binding domain + Glucose/ribitol dehydrogenase Bcin13g02230 605 Bcin13g02240 1094 "Bckap123, similar to yeast KAP123, Karyopherin beta; mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1 [Source:SGD;Acc:S000000912]" Bcin13g02250 371 Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin13g02260 541 yes Bcb1, membrane protein belonging to the acyl-coenzyme A synthase family Bcin13g02270 362 Bcin13g02280 74 Effector(V2)|Effector(V1) Bcin13g02290 112 Effector(V2) Bcin13g02300 570 Bcin13g02310 514 Bcin13g02320 353 CAZy : GH12PCW cellulose//SignalP-noTM Cellulose-binding domain, fungal + Glycoside hydrolase, family 12 + Glycoside hydrolase, family 11/12 + Concanavalin A-like lectin/glucanase domain Bcin13g02330 492 CAZy : GH72FCW //SignalP-noTM Glucanosyltransferase + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin13g02340 543 Bcin13g02350 106 Bcin13g02360 797 "Bchsl7, similar to yeast HSL7, Protein arginine N-methyltransferase; exhibits septin and Hsl1p-dependent bud neck localization and periodic Hsl1p-dependent phosphorylation; required along with Hsl1p for bud neck recruitment, phosphorylation, and degradation of Swe1p; relocalizes away from bud neck upon DNA replication stress [Source:SGD;Acc:S000000337]" Bcin13g02370 91 "Bcsmx3, similar to yeast SMX3, Core Sm protein Sm F; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm F [Source:SGD;Acc:S000006386]" Bcin13g02380 160 Protein of unknown function DUF866, eukaryotic Bcin13g02390 937 Bcin13g02400 364 Protein of unknown function DUF2419 Bcin13g02410 662 "Bcuba2, similar to yeast UBA2, Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability; [Source:SGD;Acc:S000002798]" Bcin13g02420 207 Effector(V2)|Effector(V1) "Bcoar1, similar to yeast OAR1, Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase; may comprise a type II mitochondrial fatty acid synthase along with Mct1p [Source:SGD;Acc:S000001538]" Bcin13g02430 488 CND16, CalciNeurine-Dependant (CND) gene, ATP citrate lyase Bcin13g02440 656 CND6, CalciNeurine-Dependant (CND) gene, ATP citrate lyase Bcin13g02450 202 DNA polymerase delta, subunit 4 Bcin13g02460 352 FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin13g02470 645 Transporter ABC transporter-like + AAA+ ATPase domain + ABC-2 type transporter + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin13g02480 649 SignalP-noTM Protein kinase-like domain + Prion-inhibition and propagation, HeLo domain Bcin13g02490 653 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin13g02500 228 "Bcvps24, similar to yeast VPS24, One of four subunits of the ESCRT-III complex; forms an endosomal sorting complex required for transport III (ESCRT-III) subcomplex with Did4p; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway [Source:SGD;Acc:S000001524]" Bcin13g02510 208 "Bcsba1, similar to yeast SBA1, Co-chaperone that binds and regulates Hsp90 family chaperones; plays a role in determining prion variants; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins, and like p23 can regulate telomerase activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001600]" Bcin13g02520 392 "Bcipt1, similar to yeast IPT1, Inositolphosphotransferase; involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), the most abundant sphingolipid; can mutate to resistance to the antifungals syringomycin E and DmAMP1 and to K. lactis zymocin [Source:SGD;Acc:S000002479]" Bcin13g02530 104 Effector(V1) "Bcelc1, similar to yeast ELC1, Elongin C, conserved among eukaryotes; forms a complex with Cul3p that polyubiquitylates monoubiquitylated RNA polymerase II to trigger its proteolysis; plays a role in global genomic repair [Source:SGD;Acc:S000005967]" Bcin13g02540 159 SignalP-noTM Bcin13g02550 567 Amidase + Amidase, conserved site + Amidase signature domain Bcin13g02560 292 Bcin13g02570 752 Bcin13g02580 974 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin13g02590 352 Major intrinsic protein + Aquaporin-like Bcin13g02600 637 Bcin13g02610 71 Bcin13g02620 652 Arrestin-like, N-terminal + Arrestin C-terminal-like domain + Immunoglobulin E-set Bcin13g02630 555 "Bcmch1, similar to yeast MCH1, Protein with similarity to mammalian monocarboxylate permeases; monocarboxylate permeases are involved in transport of monocarboxylic acids across the plasma membrane but mutant is not deficient in monocarboxylate transport [Source:SGD;Acc:S000002212]" Bcin13g02640 572 CAZy : GH28PCW pectin//SignalP-noTM Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin13g02650 548 "Bccct5, similar to yeast CCT5, Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo [Source:SGD;Acc:S000003825]" Bcin13g02660 747 Zinc finger, CCCH-type Bcin13g02670 264 Histidine phosphatase superfamily, clade-1 + Histidine phosphatase superfamily Bcin13g02680 464 Alpha/Beta hydrolase fold Bcin13g02690 611 Glycosyltransferase, DXD sugar-binding motif + Nucleotide-diphospho-sugar transferases Bcin13g02700 157 Bcin13g02710 94 SignalP-noTM//Effector(V2)|Effector(V1) Bcin13g02720 1501 yes Transporter BcatrD, ABC-transporter Bcin13g02730 411 Ribosomal protein S13-like, H2TH + DNA glycosylase/AP lyase, catalytic domain + DNA glycosylase/AP lyase, H2TH DNA-binding Bcin13g02740 234 Effector(V2)|Effector(V1) "Bcpex11, similar to yeast PEX11, Peroxisomal protein required for medium-chain fatty acid oxidation; also required for peroxisome proliferation, possibly by inducing membrane curvature; localization regulated by phosphorylation; transcription regulated by Adr1p and Pip2p-Oaf1p [Source:SGD;Acc:S000005507]" Bcin13g02750 466 Major facilitator superfamily + Major facilitator superfamily domain Bcin13g02760 631 SignalP-noTM Bcin13g02770 701 Heterokaryon incompatibility Bcin13g02780 506 Transporter General substrate transporter + Major facilitator superfamily domain Bcin13g02790 197 NUDIX hydrolase domain + NUDIX hydrolase domain-like Bcin13g02800 429 Zinc finger, MIZ-type + Zinc finger, RING/FYVE/PHD-type + E3 SUMO-protein ligase Nse2 (Mms21) Bcin13g02810 1224 Bcin13g02820 126 Effector(V2) Bcin13g02830 760 Helicase, C-terminal + DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site + Helicase-associated domain + DEAD/DEAH box helicase domain + Domain of unknown function DUF1605 + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin13g02840 192 Effector(V1) "Bctaf10, similar to yeast TAF10, Subunit (145 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification [Source:SGD;Acc:S000002574]" Bcin13g02850 93 Effector(V1) "Bcrsm19, similar to yeast RSM19, Mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S19 ribosomal protein [Source:SGD;Acc:S000005320]" Bcin13g02860 758 "Bcmre11, similar to yeast MRE11, Nuclease subunit of the MRX complex with Rad50p and Xrs2p; complex functions in repair of DNA double-strand breaks and in telomere stability; Mre11p associates with Ser/Thr-rich ORFs in premeiotic phase; nuclease activity required for MRX function; widely conserved; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000004837]" Bcin13g02870 889 P-loop containing nucleoside triphosphate hydrolase + NWD NACHT-NTPase, N-terminal Bcin13g02880 643 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain Bcin13g02900 779 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin13g02910 474 Copper fist DNA-binding Bcin13g02920 105 Bcin13g02930 234 Effector(V2)|Effector(V1) SET domain Bcin13g02940 1586 BTB/POZ-like + Regulator of chromosome condensation, RCC1 + Ankyrin repeat + Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II + BTB/POZ fold + Ankyrin repeat-containing domain Bcin13g02950 261 Bcin13g02960 438 Protease//SignalP-noTM Peptidase M14, carboxypeptidase A Bcin13g02970 1057 Protease Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin13g02980 199 "Bctsr2, similar to yeast TSR2, Protein with a potential role in pre-rRNA processing [Source:SGD;Acc:S000004427]" Bcin13g02990 438 BSD Bcin13g03000 632 yes Bzip transcription factor//Signaling pathway Bap1, Bzip transcription factor Bcin13g03010 841 CAZy : GH5PCW/FCW Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin13g03020 400 Transketolase-like, pyrimidine-binding domain + Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II + Thiamin diphosphate-binding fold + Transketolase, C-terminal domain Bcin13g03030 196 Effector(V1) Bcin13g03040 988 P-loop containing nucleoside triphosphate hydrolase Bcin13g03050 317 Carbon-nitrogen hydrolase Bcin13g03060 849 DNA repair protein Rad4 + Rad4/PNGase transglutaminase-like fold + Rad4 beta-hairpin domain 1 + Rad4 beta-hairpin domain 2 + Rad4 beta-hairpin domain 3 Bcin13g03070 337 Bcin13g03080 493 SignalP-noTM Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin13g03090 312 Protease Alpha/beta hydrolase fold-1 + Epoxide hydrolase-like + Alpha/Beta hydrolase fold Bcin13g03100 330 NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin13g03110 311 Bcpio2, Gene with a peak of expression during the Outset of colonization Bcin13g03120 408 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin13g03130 535 Bcin13g03160 160 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Extracellular membrane protein, CFEM domain Bcin13g03170 642 SignalP-noTM Lysophospholipase, catalytic domain + Acyl transferase/acyl hydrolase/lysophospholipase Bcin13g03180 732 Heterokaryon incompatibility Bcin13g03190 675 Macro domain Bcin13g03200 208 Bcin13g03210 348 Glyoxalase/fosfomycin resistance/dioxygenase domain + Glyoxalase I + Glyoxalase I, conserved site + Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Bcin13g03220 576 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + D-3-phosphoglycerate dehydrogenase + NAD(P)-binding domain + Allosteric substrate binding domain Bcin13g03230 429 SET domain Bcin13g03240 198 Effector(V1) Bcin13g03250 788 "Bcmam3, similar to yeast MAM3, Protein required for normal mitochondrial morphology; has similarity to hemolysins [Source:SGD;Acc:S000005421]" Bcin13g03260 729 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin13g03270 450 Bcin13g03280 249 Effector(V2)|Effector(V1) Bcin13g03290 984 Bcin13g03300 156 Bcin13g03310 305 "Bcdpp1, similar to yeast DPP1, Diacylglycerol pyrophosphate (DGPP) phosphatase; zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism [Source:SGD;Acc:S000002692]" Bcin13g03320 246 "Bcmed7, similar to yeast MED7, Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation [Source:SGD;Acc:S000005495]" Bcin13g03330 56 Effector(V2)|Effector(V1) Bcin13g03340 1386 Ankyrin repeat + NACHT nucleoside triphosphatase + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase + Fungal N-terminal domain of STAND protein Bcin13g03350 321 CAZy : GH12PCW cellulose//SignalP-noTM Glycoside hydrolase, family 12 + Glycoside hydrolase, family 11/12 + Concanavalin A-like lectin/glucanase domain Bcin13g03360 347 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin13g03370 112 Bcin13g03380 411 Bcin13g03390 143 SignalP-noTM Bcin13g03400 111 Bcin13g03410 383 Protease//SignalP-noTM Platelet-activating factor acetylhydrolase + Alpha/Beta hydrolase fold Bcin13g03420 292 Fumarylacetoacetase, C-terminal-related Bcin13g03430 430 Protein of unknown function DUF3500 Bcin13g03440 269 Bcin13g03450 1097 "Bcmet10, similar to yeast MET10, Subunit alpha of assimilatory sulfite reductase; complex converts sulfite into sulfide [Source:SGD;Acc:S000001926]" Bcin13g03460 119 Effector(V1) Bcin13g03470 139 Effector(V1) Bcin13g03480 262 "Bcfmp52, similar to yeast FMP52, Protein of unknown function; localized to the mitochondrial outer membrane; induced by treatment with 8-methoxypsoralen and UVA irradiation [Source:SGD;Acc:S000000806]" Bcin13g03490 1186 SNF2-related + Helicase, C-terminal + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin13g03500 383 "Bcbcd1, similar to yeast BCD1, Essential protein required for the accumulation of box C/D snoRNA [Source:SGD;Acc:S000001082]" Bcin13g03510 314 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin13g03520 1133 Rab-GTPase-TBC domain Bcin13g03530 165 Bcin13g03540 78 Effector(V1) Bcin13g03550 282 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin13g03560 176 Bcin13g03570 401 Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin13g03580 95 Effector(V2)|Effector(V1) Bcin13g03590 248 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin13g03600 136 Ribosomal protein L26/L24P, eukaryotic/archaeal + KOW + Ribosomal protein L24/L26, conserved site + Translation protein SH3-like domain + Ribosomal protein L2 domain 2 Bcin13g03610 1548 Carbohydrate-binding WSC Bcin13g03620 1053 SignalP-TM Carbohydrate-binding WSC Bcin13g03630 458 CAZy : GH76FCW //SignalP-noTM Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase + Mannan endo-1,6-alpha-mannosidase Bcin13g03640 444 CAZy : CBM18,GH16FCW //SignalP-noTM Bccrh3, Chitin transglycosylase Bcin13g03650 238 Effector(V2)|Effector(V1) SANT/Myb domain + Homeodomain-like + Myb-like domain + Myb domain Bcin13g03660 320 Bcin13g03670 332 HotDog domain Bcin13g03680 537 SignalP-noTM Bcprd11, Peroxidase Bcin13g03690 207 Bcin13g03700 669 ERCC4 domain + Mms4/EME1/EME2 Bcin13g03710 976 NB-ARC + Tetratricopeptide-like helical domain + P-loop containing nucleoside triphosphate hydrolase Bcin13g03720 401 SignalP-noTM Intradiol ring-cleavage dioxygenase, C-terminal + Intradiol ring-cleavage dioxygenase, core Bcin13g03730 936 DENN domain + uDENN domain Bcin13g03740 399 tRNA wybutosine synthesizing protein 2 + S-adenosyl-L-methionine-dependent methyltransferase + SAM-dependent methyltransferase TRM5/TYW2-type Bcin13g03750 206 SignalP-noTM "Bcssp120, similar to yeast SSP120, Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern [Source:SGD;Acc:S000004240]" Bcin13g03760 401 Origin recognition complex, subunit 6 Bcin13g03770 1733 Kinesin motor domain + Kinesin motor domain, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin13g03780 140 Effector(V2) Sterile alpha motif domain + Sterile alpha motif/pointed domain Bcin13g03790 458 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin13g03800 503 CAZy : GT4 "Bcalg2, similar to yeast ALG2, Mannosyltransferase in the N-linked glycosylation pathway; catalyzes two consecutive steps in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol [Source:SGD;Acc:S000003033]" Bcin13g03810 282 Crotonase superfamily + ClpP/crotonase-like domain Bcin13g03820 2172 Leucine-rich repeat + Leucine-rich repeat, typical subtype + Leucine-rich repeat domain, L domain-like Bcin13g03830 1225 Bcin13g03840 1324 "Bckcs1, similar to yeast KCS1, Inositol hexakisphosphate and inositol heptakisphosphate kinase; generation of high energy inositol pyrophosphates by Kcs1p is required for many processes such as vacuolar biogenesis, stress response, and telomere maintenance; inositol hexakisphosphate is also known as IP6; inositol heptakisphosphate is also known as IP7 [Source:SGD;Acc:S000002424]" Bcin13g03850 774 "Bcmak5, similar to yeast MAK5, Essential nucleolar protein; putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus; involved in biogenesis of large (60S) ribosomal subunits [Source:SGD;Acc:S000000346]" Bcin13g03860 395 "Bctrm7, similar to yeast TRM7, 2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of the tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively [Source:SGD;Acc:S000000265]" Bcin13g03870 1201 Transporter P-type ATPase + Heavy metal-associated domain, HMA + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, cytoplasmic domain N Bcin13g03880 484 "Bcade13, similar to yeast ADE13, Adenylosuccinate lyase; catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency [Source:SGD;Acc:S000004351]" Bcin13g03890 337 NADP-dependent oxidoreductase domain Bcin13g03900 459 "Bcbio3, similar to yeast BIO3, 7,8-diamino-pelargonic acid aminotransferase (DAPA); catalyzes the second step in the biotin biosynthesis pathway; BIO3 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; BIO3 and BIO4 were acquired by horizontal gene transfer (HGT) from bacteria [Source:SGD;Acc:S000005341]" Bcin13g03910 659 yes Zn2/Cys6 + fungal trans transcription factor BcTbs1, Zn(2)-C6 fungal-type DNA-binding domain Bcin13g03920 360 Bcin13g03930 247 Bcin13g03940 234 Bcin13g03950 506 CAZy : GH54,CBM42PCW hemicellulose or pectin//SignalP-noTM//Early secretome Alpha-L-arabinofuranosidase B, arabinose-binding domain + Concanavalin A-like lectin/glucanase domain + Alpha-L-arabinofuranosidase B, catalytic Bcin13g03960 726 Cys2His2 transcription factor Zinc finger, C2H2 + Heterokaryon incompatibility Bcin13g03970 338 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin13g03980 856 Signaling pathway Bcste20, Mitogen-activated protein kinase (MAPK) : p21-activated kinase (PAK) Bcin13g03990 1304 "Bcscp160, similar to yeast SCP160, Essential RNA-binding G protein effector of mating response pathway; ligand-activated RNA-binding protein that delivers RNAs involved in polarization and perpetualizing mating signal to shmoo tip during pheromone signaling; Scp160p-mediated RNA trafficking essential for chemotropism and successful mating; mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins [Source:SGD;Acc:S000003616]" Bcin13g04000 357 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin13g04010 403 SH3 domain + Ysc84 actin-binding domain + Variant SH3 domain Bcin13g04020 97 Bcin13g04030 561 Arf GTPase activating protein Bcin13g04040 209 Effector(V2)|Effector(V1) "Bcmxr2, similar to yeast MXR2, Methionine-R-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan [Source:SGD;Acc:S000000538]" Bcin13g04050 463 Bcin13g04060 687 Monooxygenase, FAD-binding + Acetoacetate decarboxylase + Acetoacetate decarboxylase beta barrel domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin13g04070 185 RmlC-like cupin domain + Cupin 2, conserved barrel + RmlC-like jelly roll fold Bcin13g04080 599 Protease Xaa-Pro dipeptidyl-peptidase-like domain + CocE/Serine esterase + Galactose-binding domain-like + Xaa-Pro dipeptidyl-peptidase, C-terminal + Alpha/Beta hydrolase fold Bcin13g04090 858 Zn2/Cys6 transcription factor + Cys2His2 + Fungal_trans Zn(2)-C6 fungal-type DNA-binding domain + Zinc finger, C2H2 + Transcription factor domain, fungi + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin13g04100 295 Effector(V2) Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B + Extradiol aromatic ring-opening dioxygenase, DODA type Bcin13g04110 497 Aldehyde dehydrogenase domain + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain + Aldehyde dehydrogenase, C-terminal Bcin13g04120 125 Effector(V2)|Effector(V1) Bcin13g04130 634 Bcin13g04140 940 Regulatory Factor X (RFX) transcription factor "Bcrsc9, similar to yeast RSC9, Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway [Source:SGD;Acc:S000004596]" Bcin13g04150 339 Transporter Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin13g04160 305 Bcin13g04170 376 CAZy : GT25 //SignalP-noTM Bcin13g04180 101 Bcin13g04190 283 Effector(V1) Bcin13g04200 226 SignalP-noTM Bcin13g04210 225 DSBA-like thioredoxin domain + Thioredoxin-like fold + HCCA isomerase/glutathione S-transferase kappa Bcin13g04220 1521 DDHD Bcin13g04230 1531 Bcin13g04240 651 Monooxygenase, FAD-binding + Thioredoxin-like fold + Phenol hydroxylase, C-terminal dimerisation domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin13g04250 517 Protease "Bculp1, similar to yeast ULP1, Protease that specifically cleaves Smt3p protein conjugates; required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase; sequestered to the nucleolus under stress conditions [Source:SGD;Acc:S000005941]" Bcin13g04260 1021 "Bcduf1, similar to yeast DUF1, Ubiquitin-binding protein of unknown function; contains one WD40 repeat in a beta-propeller fold; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; homolog of human WDR48/UAF1, which is involved in regulating the Fanconi anemia pathway; deletion mutant is sensitive to various chemicals including phenanthroline, sanguinarine, and nordihydroguaiaretic acid [Source:SGD;Acc:S000005447]" Bcin13g04270 1045 "Bcppm2, similar to yeast PPM2, AdoMet-dependent tRNA methyltransferase; also involved in methoxycarbonylation; required for the synthesis of wybutosine (yW), a modified guanosine found at the 3'-position adjacent to the anticodon of phe-tRNA; similarity to Ppm1p [Source:SGD;Acc:S000005501]" Bcin13g04280 434 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin13g04290 464 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin13g04300 285 Transporter "Bcpet8, similar to yeast PET8, S-adenosylmethionine transporter of the mitochondrial inner membrane; member of the mitochondrial carrier family; required for biotin biosynthesis and respiratory growth [Source:SGD;Acc:S000004948]" Bcin13g04310 627 tRNA(Ile)-lysidine/2-thiocytidine synthase + tRNA(Ile)-lysidine synthase + tRNA(Ile)-lysidine synthase, N-terminal + Rossmann-like alpha/beta/alpha sandwich fold Bcin13g04320 115 Bcin13g04330 695 "Bcpps1, similar to yeast PPS1, Protein phosphatase; has specificity for serine, threonine, and tyrosine residues; has a role in the DNA synthesis phase of the cell cycle [Source:SGD;Acc:S000000480]" Bcin13g04340 165 Effector(V2)|Effector(V1) Bcin13g04350 402 "Bcdom34, similar to yeast DOM34, Protein that facilitates ribosomal subunit dissociation; Dom34-Hbs1 complex and Rli1p have roles in dissociating inactive ribosomes to facilitate translation restart, particularly ribosomes stalled in 3' UTRs; required for RNA cleavage in no-go decay, but reports conflict on endonuclease activity; Pelota ortholog; protein abundance increases in response to DNA replication stress; DOM34 has a paralog, YCL001W-B, that arose from the whole genome duplication [Source:SGD;Acc:S000004946]" Bcin13g04360 325 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin13g04370 137 Effector(V1) Bcin13g04380 1703 "Bcrpa190, similar to yeast RPA190, RNA polymerase I largest subunit A190 [Source:SGD;Acc:S000005868]" Bcin13g04390 505 "Bcprp3, similar to yeast PRP3, Splicing factor; component of the U4/U6-U5 snRNP complex [Source:SGD;Acc:S000002881]" Bcin13g04400 797 Xeroderma pigmentosum group D protein + Helicase-like, DEXD box c2 type + ATP-dependent helicase, C-terminal + DEAD2 + Domain of unknown function DUF1227 + DNA helicase (DNA repair), Rad3 type + Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type + P-loop containing nucleoside triphosphate hydrolase Bcin13g04410 136 Effector(V1) Histone H3/CENP-A + Histone core + Histone-fold Bcin13g04420 103 Effector(V1) Histone H4 + Histone-fold + Histone H4, conserved site Bcin13g04430 1576 Shikimate kinase/Threonine synthase-like 1 + 3-dehydroquinate dehydratase type I + Enolpyruvate transferase domain + 3-phosphoshikimate 1-carboxyvinyltransferase + Pentafunctional AroM protein + Shikimate dehydrogenase, AroM-type + Shikimate dehydrogenase substrate binding, N-terminal + Aldolase-type TIM barrel + RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta + 3-dehydroquinate synthase AroB + NAD(P)-binding domain + 3-dehydroquinate dehydratase, active site + Shikimate kinase, conserved site + 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site + P-loop containing nucleoside triphosphate hydrolase + 3-dehydroquinate synthase domain + Shikimate kinase/gluconokinase Bcin13g04440 855 CAZy : GH78PCW pectin//SignalP-noTM Bacterial alpha-L-rhamnosidase + Six-hairpin glycosidase-like + Six-hairpin glycosidase Bcin13g04450 149 Effector(V1) Bcin13g04460 429 Bcin13g04470 752 Cys2His2 transcription factor Bcltf7, Light-responsive Cys2His2 transcription factor Bcin13g04480 221 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 Bcin13g04490 564 Bcin13g04500 1048 "Bcuso1, similar to yeast USO1, Essential protein involved in vesicle-mediated ER to Golgi transport; binds membranes and functions during vesicle docking to the Golgi; required for assembly of the ER-to-Golgi SNARE complex [Source:SGD;Acc:S000002216]" Bcin13g04510 966 "Bcrat1, similar to yeast RAT1, Nuclear 5' to 3' single-stranded RNA exonuclease; involved in RNA metabolism, including rRNA and snRNA processing as well as poly (A+) dependent and independent mRNA transcription termination; required for cotranscriptional pre-rRNA cleavage [Source:SGD;Acc:S000005574]" Bcin13g04520 2589 CRAL-TRIO domain + Ras GTPase-activating protein + Rho GTPase activation protein + Armadillo-type fold + Ras GTPase-activating protein, conserved site Bcin13g04530 613 SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin13g04540 1069 "Bcils1, similar to yeast ILS1, Cytoplasmic isoleucine-tRNA synthetase; target of the G1-specific inhibitor reveromycin A [Source:SGD;Acc:S000000172]" Bcin13g04550 62 Effector(V2)|Effector(V1) Bcin13g04560 1329 Sfi1 spindle body Bcin13g04570 1317 "Bcrav1, similar to yeast RAV1, Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the RAVE complex promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate [Source:SGD;Acc:S000003794]" Bcin13g04580 215 Effector(V2)|Effector(V1) Bcin13g04590 265 Bcin13g04600 302 Bcin13g04610 1210 CAZy : GT1 UDP-glucuronosyl/UDP-glucosyltransferase + Glycosyltransferase family 28, N-terminal domain Bcin13g04620 713 Bcin13g04630 902 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Pleckstrin homology-like domain Bcin13g04640 303 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin13g04650 502 SWIB/MDM2 domain Bcin13g04660 377 "Bchym1, similar to yeast HYM1, Component of the RAM signaling network; is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response [Source:SGD;Acc:S000001672]" Bcin13g04670 549 Protein arginine N-methyltransferase + S-adenosyl-L-methionine-dependent methyltransferase Bcin13g04680 735 Oligopeptide transporter, OPT superfamily Bcin13g04690 1629 Bcphy1, Phytochrome-like 1, Histidine kinase - group VIII, potential red light sensor Bcin13g04700 277 FMN-binding split barrel + Pyridoxamine 5'-phosphate oxidase-related Bcin13g04710 833 Bcin13g04720 488 "Bcrrd1, similar to yeast RRD1, Peptidyl-prolyl cis/trans-isomerase; activator of the phosphotyrosyl phosphatase activity of PP2A; involved in G1 phase progression, microtubule dynamics, bud morphogenesis and DNA repair; required for rapid reduction of Sgs1p levels in response to rapamycin; subunit of the Tap42p-Sit4p-Rrd1p complex; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000001415]" Bcin13g04730 121 Bcin13g04740 227 Effector(V2) Bcin13g04750 394 Nitrous oxide reductase, N-terminal + WD40/YVTN repeat-like-containing domain + Lactonase, 7-bladed beta propeller + Cytochrome cd1-nitrite reductase-like, haem d1 domain Bcin13g04760 274 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin13g04780 227 yes Effector(V2)|Effector(V1) LPS-induced tumour necrosis factor alpha factor Bcin13g04790 607 Bcin13g04800 533 Cys2His2 transcription factor Zinc finger, U1-type + Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin13g04810 1289 HECT + Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain Bcin13g04820 553 Transporter Bchex2, Similar to MFS sugar transporter Bcin13g04830 692 "Bchse1, similar to yeast HSE1, Subunit of the endosomal Vps27p-Hse1p complex; complex is required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes [Source:SGD;Acc:S000000994]" Bcin13g04840 949 Activator of mitotic machinery Cdc14 phosphatase activation C-terminal Bcin13g04850 683 CAZy : GH78PCW pectin//SignalP-noTM Bacterial alpha-L-rhamnosidase + Six-hairpin glycosidase-like Bcin13g04860 494 Pleckstrin homology domain + Pleckstrin homology-like domain Bcin13g04870 1536 Transporter ABC transporter-like + AAA+ ATPase domain + CDR ABC transporter + ABC-2 type transporter + P-loop containing nucleoside triphosphate hydrolase + ABC-transporter extracellular N-terminal domain Bcin13g04880 961 "Bcctr86, similar to yeast CTR86, Essential protein of unknown function; with orthologs in Ashbya gossypii and Candida albicans; similar to human ATXN10, mutations in which cause spinocerebellar ataxia type 10; codon usage corresponds to that observed for yeast genes expressed at low levels; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000000650]" Bcin13g04890 490 Bcin13g04900 256 Bcin13g04910 941 "Bcatg13, similar to yeast ATG13, Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; contains a HORMA domain required for autophagy and for recruitment of the phosphatidylinositol 3-kinase complex subunit Atg14p to the pre-autophagosomal structure [Source:SGD;Acc:S000006389]" Bcin13g04920 497 Alcohol dehydrogenase, iron-type Bcin13g04930 662 Bcin13g04940 274 Bcin13g04950 497 Bcin13g04960 522 Bcin13g04970 506 Bcin13g04980 282 GPR1/FUN34/yaaH Bcin13g04990 290 Bcin13g05010 536 Ankyrin repeat + Ankyrin repeat-containing domain Bcin13g05020 537 "Bcthr4, similar to yeast THR4, Threonine synthase; conserved protein that catalyzes formation of threonine from O-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway [Source:SGD;Acc:S000000649]" Bcin13g05030 125 Effector(V2)|Effector(V1) S-adenosyl-L-methionine-dependent methyltransferase Bcin13g05040 232 Effector(V1) Bcin13g05050 379 Bcin13g05060 211 Bcin13g05070 286 Protein of unknown function DUF829, TMEM53 Bcin13g05080 624 RNA recognition motif domain + Regulator of nonsense-mediated decay, UPF3 + Nucleotide-binding alpha-beta plait domain Bcin13g05090 408 "Bcsit4, similar to yeast SIT4, Type 2A-related serine-threonine phosphatase; functions in the G1/S transition of the mitotic cycle; regulator of COPII coat dephosphorylation; required for ER to Golgi traffic; interacts with Hrr25p kinase; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization; similar to human PP6 [Source:SGD;Acc:S000002205]" Bcin13g05100 280 Effector(V2) FMN-binding split barrel Bcin13g05110 549 CAZy : GH13Energy //Early secretome Glycosyl hydrolase, family 13, catalytic domain + Glycosyl hydrolase, family 13, all-beta + Glycoside hydrolase, catalytic domain + Alpha-amylase, domain of unknown function DUF1966, C-terminal + Glycoside hydrolase superfamily Bcin13g05120 250 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin13g05130 696 Transporter Amino acid/polyamine transporter I Bcin13g05140 501 Cytochrome P450 + Cytochrome P450, E-class, group II + Cytochrome P450, E-class, CYP52 + Cytochrome P450, conserved site Bcin13g05150 155 Bzip transcription factor Basic-leucine zipper domain Bcin13g05160 94 Bcin13g05170 234 Bcin13g05180 222 Effector(V1) Bcin13g05190 293 Bcin13g05200 242 Effector(V1) Copper fist DNA-binding Bcin13g05210 217 "Bcctr3, similar to yeast CTR3, High-affinity copper transporter of the plasma membrane; acts as a trimer; gene is disrupted by a Ty2 transposon insertion in many laboratory strains of S. cerevisiae [Source:SGD;Acc:S000004403]" Bcin13g05220 361 "Bctma46, similar to yeast TMA46, Protein of unknown function that associates with translating ribosomes; interacts with GTPase Rbg1p [Source:SGD;Acc:S000005617]" Bcin13g05230 58 Oligosaccaryltransferase Bcin13g05240 267 Effector(V1) "Bcyra1, similar to yeast YRA1, Nuclear polyadenylated RNA-binding protein; required for export of poly(A)+ mRNA from the nucleus; proposed to couple mRNA export with 3' end processing via its interactions with Mex67p and Pcf11p; interacts with DBP2; inhibits the helicase activity of Dbp2; functionally redundant with Yra2p, another REF family member [Source:SGD;Acc:S000002789]" Bcin13g05250 976 "Bcpep5, similar to yeast PEP5, Histone E3 ligase, component of CORVET membrane tethering complex; peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; interacts with Pep7p; involved in ubiquitylation and degradation of excess histones [Source:SGD;Acc:S000004844]" Bcin13g05260 415 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin13g05270 572 Band 7 protein + Flotillin family Bcin13g05280 265 Bcin13g05290 1484 Ankyrin repeat + Ankyrin repeat-containing domain + NWD NACHT-NTPase, N-terminal Bcin13g05300 464 CAZy : GT71 Alpha-mannosyltransferase + Nucleotide-diphospho-sugar transferases Bcin13g05310 158 Bcin13g05320 244 Bcin13g05330 174 Bcin13g05340 243 yes Bchp1, Heterochromatin protein 1 Bcin13g05350 359 Zinc finger, RING-type + SAP domain + Zinc finger, SWIM-type + Zinc finger, RING/FYVE/PHD-type Bcin13g05360 978 Dynamin central domain + Dynamin, GTPase domain + GTPase effector domain, GED + Dynamin superfamily + P-loop containing nucleoside triphosphate hydrolase Bcin13g05370 441 Bacterial transferase hexapeptide repeat + Nucleotidyl transferase + Trimeric LpxA-like + Hexapeptide transferase, conserved site + Nucleotide-diphospho-sugar transferases Bcin13g05380 439 NADH:flavin oxidoreductase/NADH oxidase, N-terminal + Aldolase-type TIM barrel Bcin13g05390 827 Zinc finger, CCCH-type + Zinc finger, CHY-type Bcin13g05400 583 Protein of unknown function DUF1752, fungi + Protein of unknown function DUF3295 Bcin13g05410 1150 PAZ domain + Piwi domain + Ribonuclease H-like domain + Domain of unknown function DUF1785 Bcin13g05420 384 Sulphur transport domain Bcin13g05430 117 Effector(V1) Bcin13g05440 319 Bcin13g05450 886 Bcin13g05460 488 "Bclsb5, similar to yeast LSB5, Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; may mediate disassembly of the Pan1 complex from the endocytic coat [Source:SGD;Acc:S000000539]" Bcin13g05470 168 Effector(V1) Bcin13g05480 637 "Bctrm2, similar to yeast TRM2, tRNA methyltransferase; 5-methylates the uridine residue at position 54 of tRNAs and may also have a role in tRNA stabilization or maturation; endo-exonuclease with a role in DNA repair [Source:SGD;Acc:S000001764]" Bcin13g05490 167 Bcin13g05500 1788 WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin13g05510 411 "Bcmrps5, similar to yeast MRPS5, Mitochondrial ribosomal protein of the small subunit [Source:SGD;Acc:S000000455]" Bcin13g05520 102 DASH complex subunit Dad3 Bcin13g05530 439 "Bcarp3, similar to yeast ARP3, Essential component of the Arp2/3 complex; Arp2/3 is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity [Source:SGD;Acc:S000003826]" Bcin13g05540 662 Protease Peptidase T2, asparaginase 2 + Nucleophile aminohydrolases, N-terminal Bcin13g05550 356 "Bctfb4, similar to yeast TFB4, Subunit of TFIIH complex; involved in transcription initiation, similar to 34 kDa subunit of human TFIIH; interacts with Ssl1p [Source:SGD;Acc:S000006260]" Bcin13g05560 717 "Bcshe4, similar to yeast SHE4, Protein containing a UCS (UNC-45/CRO1/SHE4) domain; binds to myosin motor domains to regulate myosin function; involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization [Source:SGD;Acc:S000005561]" Bcin13g05570 926 Bcin13g05580 351 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin13g05590 452 Cys2His2 transcription factor Zinc finger, C2H2 + AT hook, DNA-binding motif Bcin13g05600 410 Bcin13g05610 272 yes BcCPA1, Bccap1, F-actin capping protein Bcin13g05620 139 Effector(V1) "Bccyb5, similar to yeast CYB5, Cytochrome b5; involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation [Source:SGD;Acc:S000005055]" Bcin13g05630 235 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin13g05640 565 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin13g05650 185 Bcin13g05660 298 Zinc finger, RING-type + Zinc finger, RING-CH-type + Zinc finger, RING/FYVE/PHD-type Bcin13g05670 359 SignalP-noTM Carbon-nitrogen hydrolase Bcin13g05680 117 Effector(V2)|Effector(V1) Bcin13g05690 175 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin13g05700 166 SignalP-noTM//Effector(V1) Bcin13g05710 724 CAZy : CBM32,AA5 //SignalP-noTM Bcgox1, Galactose oxidase Bcin13g05720 513 Bcprd1, Dyp-type peroxidase Bcin13g05730 411 Domain of unknown function DUF2183 Bcin13g05740 346 Bcin13g05750 915 "Bcrtp1, similar to yeast RTP1, Protein required for the nuclear import and biogenesis of RNA pol II; conflicting evidence on whether null mutant is viable with elongated buds, or inviable; interacts with Rpb2, Rpb3, Nup116p, Nup100p and components of the R2TP complex (Rvb1p, Rvb2p, Pih1p); similar to human TMCO7 gene [Source:SGD;Acc:S000004797]" Bcin13g05760 256 CAZy : CE5PCW hemicellulose//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Cutinase + Cutinase, monofunctional + Alpha/Beta hydrolase fold Bcin13g05770 757 Domain of unknown function DUF1793 + Domain of unknown function DUF4965 + Domain of unknown function DUF4964 + Domain of unknown function DUF5127 Bcin13g05780 518 SignalP-noTM Domain of unknown function DUF2183 Bcin13g05790 466 Bcin13g05800 589 SignalP-noTM Histidine phosphatase superfamily, clade-2 + Histidine phosphatase superfamily Bcin13g05810 496 Aldehyde dehydrogenase domain + Aldehyde dehydrogenase, cysteine active site + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain + Aldehyde dehydrogenase, C-terminal + Aldehyde dehydrogenase, glutamic acid active site Bcin13g05820 709 "Bctbf1, similar to yeast TBF1, Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression; caps DSB flanked by long T2AG3 repeats and blocks checkpoint activation [Source:SGD;Acc:S000006049]" Bcin13g05830 411 yes SM cluster STC3 (KE) Bcstc3, sesquiterpene cyclase Bcin13g05840 392 SM cluster STC3 Cytochrome P450 Bcin13g05850 387 Bcin13g05860 553 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin13g05870 620 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin13g05880 813 Protein of unknown function DUF4238 Bcin14g00010 251 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin14g00020 1177 P-loop containing nucleoside triphosphate hydrolase Bcin14g00030 256 Bcin14g00040 175 Effector(V2)|Effector(V1) Bcin14g00050 174 Bcin14g00060 541 Bcin14g00070 232 Effector(V2) S-adenosyl-L-methionine-dependent methyltransferase Bcin14g00080 215 Effector(V2) Bcin14g00090 432 Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase, C-terminal domain + Acyl-CoA dehydrogenase/oxidase, N-terminal Bcin14g00100 95 Effector(V1) NADH:ubiquinone oxidoreductase, B18 subunit Bcin14g00110 270 "Bcdcg1, similar to yeast DCG1, Protein of unknown function; expression is sensitive to nitrogen catabolite repression and regulated by Dal80p; contains transmembrane domain [Source:SGD;Acc:S000001469]" Bcin14g00120 389 "Bcarp2, similar to yeast ARP2, Essential component of the Arp2/3 complex; Arp2/3 is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity; required for efficient Golgi-to-ER trafficking in COPI mutants [Source:SGD;Acc:S000002187]" Bcin14g00130 499 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin14g00140 419 "Bcssn3, similar to yeast SSN3, Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression [Source:SGD;Acc:S000005963]" Bcin14g00150 266 Effector(V1) Bcin14g00160 186 Effector(V2)|Effector(V1) "Bcarf3, similar to yeast ARF3, Glucose-repressible ADP-ribosylation factor; GTPase of the Ras superfamily involved in regulating cell polarity and invasive growth; also has mRNA binding activity [Source:SGD;Acc:S000005620]" Bcin14g00170 399 "Bcsgf29, similar to yeast SGF29, Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes; HAT/Core module also contains Gcn5p, Ngg1p, and Ada2p; binds methylated histone H3K4; involved in transcriptional regulation through SAGA and TBP recruitment to target promoters and H3 acetylation [Source:SGD;Acc:S000000516]" Bcin14g00180 453 "Bcpmi40, similar to yeast PMI40, Mannose-6-phosphate isomerase; catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation [Source:SGD;Acc:S000000805]" Bcin14g00190 568 Transporter Amino acid/polyamine transporter I Bcin14g00200 402 "Bcrib1, similar to yeast RIB1, GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway [Source:SGD;Acc:S000000129]" Bcin14g00210 443 NADH:flavin oxidoreductase/NADH oxidase, N-terminal + Aldolase-type TIM barrel Bcin14g00220 301 Bcin14g00230 747 Bcin14g00240 579 SignalP-noTM Tannase/feruloyl esterase + Alpha/Beta hydrolase fold Bcin14g00250 450 Cation efflux protein + Cation efflux protein transmembrane domain + Cation efflux protein cytoplasmic domain Bcin14g00260 528 Major facilitator superfamily + Major facilitator superfamily domain Bcin14g00270 344 Taurine catabolism dioxygenase TauD/TfdA Bcin14g00280 684 Ankyrin repeat + Transcription regulator HTH, APSES-type DNA-binding domain + KilA, N-terminal/APSES-type HTH, DNA-binding + Ankyrin repeat-containing domain + MBF transcription factor complex subunit Mbp1/Res1/Res2 Bcin14g00290 346 Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin14g00300 531 Solute carrier family 35 member F3/F4 + Mannosyl phosphorylinositol ceramide synthase regulatory protein Csg2 Bcin14g00310 402 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal Bcin14g00320 505 F-box domain Bcin14g00330 189 Effector(V2)|Effector(V1) Bacterial transferase hexapeptide repeat + Trimeric LpxA-like Bcin14g00340 891 Domain of unknown function DUF1212 + Domain of unknown function DUF3815 Bcin14g00350 1043 Ankyrin repeat + Heterokaryon incompatibility + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin14g00360 723 Bcin14g00370 694 Helicase, C-terminal + DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site + Helicase-associated domain + Domain of unknown function DUF1605 + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin14g00380 805 Bcin14g00390 377 SignalP-noTM//Effector(V2)|Effector(V1)//Early secretome Bcin14g00400 682 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin14g00410 535 Protein of unknown function DUF1479 + Isopenicillin N synthase-like Bcin14g00420 390 SignalP-noTM Cysteine-rich secretory protein, allergen V5/Tpx-1-related + CAP domain Bcin14g00430 806 "Bclys4, similar to yeast LYS4, Homoaconitase; catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway [Source:SGD;Acc:S000002642]" Bcin14g00440 503 Bcin14g00450 423 Bcin14g00460 545 Zinc finger, N-recognin Bcin14g00470 879 "Bcmcm2, similar to yeast MCM2, Protein involved in DNA replication; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000000119]" Bcin14g00480 833 CAZy : GH3PCW/FCW Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + PA14 + Glycoside hydrolase superfamily + Glycoside hydrolase, family 3, active site + Fibronectin type III-like domain Bcin14g00490 121 Effector(V2)|Effector(V1) NAD(P)-binding domain Bcin14g00500 493 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin14g00510 909 CAZy : GH78PCW pectin Bacterial alpha-L-rhamnosidase + Six-hairpin glycosidase-like + Bacterial alpha-L-rhamnosidase N-terminal Bcin14g00520 517 Bcin14g00530 704 "Bcpxl1, similar to yeast PXL1, Protein that localizes to sites of polarized growth; required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; contains LIM domains and has similarity to metazoan paxillin; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000001798]" Bcin14g00540 539 "Bcino1, similar to yeast INO1, Inositol-3-phosphate synthase; involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element [Source:SGD;Acc:S000003689]" Bcin14g00550 549 Nucleic acid-binding, OB-fold Bcin14g00560 277 SM cluster PKS1//Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin14g00570 229 SM cluster PKS1//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Serine hydrolase FSH + Alpha/Beta hydrolase fold Bcin14g00580 566 Transporter//SM cluster PKS1 Major facilitator superfamily + Major facilitator superfamily domain Bcin14g00590 397 SM cluster PKS1 Bcin14g00600 2592 SM cluster PKS1 (KE) Bcpks1, Polyketide synthase Bcin14g00610 411 yes CAZy : GH28PCW pectin//Early secretome Bcpg2, Endopolygalacturonase Bcin14g00620 790 Protein of unknown function DUF3405 Bcin14g00630 519 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin14g00640 673 Bcin14g00650 935 CAZy : GH31PCW hemicellulose//SignalP-noTM//Early secretome Glycoside hydrolase family 31 + Galactose mutarotase-like domain + Glycoside hydrolase superfamily + Glycoside hydrolase family 31, N-terminal domain + Glycosyl hydrolases family 31, active site + Glycosyl hydrolases family 31, conserved site + Galactose mutarotase, N-terminal barrel Bcin14g00660 112 Effector(V2)|Effector(V1) Bcin14g00670 107 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin14g00680 234 Kinetochore Sim4 complex subunit Fta4 Bcin14g00690 287 Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin14g00700 260 Effector(V1) "Bcvps29, similar to yeast VPS29, Subunit of the membrane-associated retromer complex; endosomal protein; essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps35p and Vps26p that selects cargo proteins for endosome-to-Golgi retrieval [Source:SGD;Acc:S000001054]" Bcin14g00710 749 Shugoshin, C-terminal + Shugoshin, N-terminal Bcin14g00720 145 DASH complex subunit Dad2 Bcin14g00730 747 Bcin14g00740 154 Life-span regulatory factor Bcin14g00750 914 Bcin14g00760 296 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Survival protein SurE-like phosphatase/nucleotidase Bcin14g00770 666 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin14g00780 543 Major facilitator superfamily + Major facilitator superfamily domain Bcin14g00790 322 Nitrilase/cyanide hydratase, conserved site + Carbon-nitrogen hydrolase Bcin14g00800 217 Effector(V1) Bcin14g00810 514 SignalP-noTM//Early secretome Phytase-like domain Bcin14g00820 1077 "Bccrm1, similar to yeast CRM1, Major karyopherin; involved in export of proteins, RNAs, and ribosomal subunits from the nucleus; exportin [Source:SGD;Acc:S000003450]" Bcin14g00830 385 "Bcagx1, similar to yeast AGX1, Alanine:glyoxylate aminotransferase (AGT); catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; has similarity to mammalian and plant alanine:glyoxylate aminotransferases [Source:SGD;Acc:S000001864]" Bcin14g00840 299 "Bcnat2, similar to yeast NAT2, Protein of unknown function; has an apparent role in acetylation of N-terminal methionine residues [Source:SGD;Acc:S000003379]" Bcin14g00850 382 yes CAZy : GH28PCW pectin//SignalP-noTM//Early secretome Bcpg1, Endopolygalacturonase1, CalciNeurine-Dependant (CND) gene Bcin14g00860 327 yes CAZy : CE8PCW pectin//SignalP-noTM//Early secretome Pectinesterase, catalytic + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin14g00870 633 Major facilitator superfamily + Major facilitator superfamily domain Bcin14g00880 1026 "Bcbud6, similar to yeast BUD6, Actin- and formin-interacting protein; participates in actin cable assembly and organization as a nucleation-promoting factor (NPF) for formins Bni1p and Bnr1p; a triple helical coiled-coil domain in the C-terminal region interacts with Bni1p; involved in polarized cell growth; isolated as bipolar budding mutant; potential Cdc28p substrate [Source:SGD;Acc:S000004311]" Bcin14g00890 966 "Bcpbp1, similar to yeast PBP1, Component of glucose deprivation induced stress granules; involved in P-body-dependent granule assembly; similar to human ataxin-2; interacts with Pab1p to regulate mRNA polyadenylation; interacts with Mkt1p to regulate HO translation; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003410]" Bcin14g00900 160 Effector(V2)|Effector(V1) Winged helix-turn-helix DNA-binding domain + Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding Bcin14g00910 468 SignalP-noTM Bcin14g00920 176 Effector(V1) Protein phosphatase inhibitor Bcin14g00930 497 SignalP-noTM Bcin14g00940 1636 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter, conserved site + ABC transporter A, ABCA + P-loop containing nucleoside triphosphate hydrolase Bcin14g00950 781 SignalP-noTM TRP-like family + ML-like domain Bcin14g00960 510 "Bchas1, similar to yeast HAS1, ATP-dependent RNA helicase; involved in the biogenesis of 40S and 60S ribosome subunits; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles [Source:SGD;Acc:S000004903]" Bcin14g00970 462 HotDog domain + Hotdog acyl-CoA thioesterase (ACOT)-type domain Bcin14g00980 918 Protein of unknown function DUF3433 Bcin14g00990 585 Bcin14g01000 137 Effector(V1) Bcin14g01010 331 "Bcsdh5, similar to yeast SDH5, Protein required for flavinylation of Sdh1p; binds to Sdh1p and promotes FAD cofactor attachment, which is necessary for succinate dehydrogenase (SDH) complex assembly and activity; mutations in human ortholog PGL2 are associated with neuroendocrine tumors (paraganglioma) [Source:SGD;Acc:S000005432]" Bcin14g01020 446 SKG6/AXL2 alpha-helix transmembrane domain Bcin14g01030 381 "Bcsfa1, similar to yeast SFA1, Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase; formaldehyde dehydrogenase activity is glutathione-dependent; functions in formaldehyde detoxification and formation of long chain and complex alcohols, regulated by Hog1p-Sko1p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002327]" Bcin14g01040 90 Bcin14g01050 162 Effector(V2)|Effector(V1) Bcin14g01060 715 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin14g01070 372 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin14g01080 544 Bcin14g01090 669 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin14g01100 583 CAZy : GT71 //SignalP-TM Alpha-mannosyltransferase + Nucleotide-diphospho-sugar transferases Bcin14g01110 681 BRCT domain Bcin14g01120 602 "Bcptr2, similar to yeast PTR2, Integral membrane peptide transporter; mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p [Source:SGD;Acc:S000001801]" Bcin14g01130 395 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin14g01140 564 Bcin14g01150 129 Protein of unknown function DUF953, thioredoxin-like + Thioredoxin-like fold Bcin14g01160 136 Effector(V2)|Effector(V1) Bcin14g01170 381 Polyprenyl synthetase + Isoprenoid synthase domain + Polyprenyl synthetase, conserved site Bcin14g01180 291 Cell division protein Cdc14 Bcin14g01190 401 Bcin14g01200 151 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa BcHip1, hypersensitive response inducing protein 1 Bcin14g01210 278 Effector(V2) Bcin14g01220 270 P-loop containing nucleoside triphosphate hydrolase Bcin14g01230 1509 Transporter P-type ATPase + P-type ATPase, subfamily IV + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, cytoplasmic domain N + Phospholipid-transporting P-type ATPase + P-type ATPase, C-terminal + P-type ATPase, N-terminal Bcin14g01240 522 SM cluster PKS11-NRPS9 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin14g01250 142 SM cluster PKS11-NRPS9//Effector(V2)|Effector(V1) Dimeric alpha-beta barrel + Stress responsive alpha-beta barrel Bcin14g01260 511 SM cluster PKS11-NRPS9 Aminotransferase class-III + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin14g01270 524 SM cluster PKS11-NRPS9 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin14g01290 2545 SM cluster PKS11-NRPS9 (KE) Bcpks11, Polyketide synthase Bcin14g01300 4408 SM cluster PKS11-NRPS9 (KE) Bcnrps9, Nonribosomal peptide synthetase Bcin14g01310 199 SM cluster PKS11-NRPS9//Effector(V2)|Effector(V1) Bcin14g01320 292 SM cluster PKS11-NRPS9 Alpha/Beta hydrolase fold Bcin14g01330 567 Transporter//SM cluster PKS11-NRPS9 Tetracycline resistance protein, TetA/multidrug resistance protein MdtG + Major facilitator superfamily + Major facilitator superfamily domain Bcin14g01340 386 SM cluster PKS11-NRPS9 Taurine catabolism dioxygenase TauD/TfdA Bcin14g01350 143 Effector(V1) Polyketide cyclase/dehydrase + START-like domain Bcin14g01360 477 Indoleamine 2,3-dioxygenase Bcin14g01370 495 SignalP-TM Bcin14g01380 591 Bcaif1, AIF-like oxidoreductase 1 Bcin14g01390 410 SignalP-noTM Ureohydrolase + Ureohydrolase, manganese-binding site + Ureohydrolase domain Bcin14g01400 1079 Protease Peptidase C2, calpain, catalytic domain + Peptidase C2, calpain family Bcin14g01410 575 Transporter Amino acid/polyamine transporter I + Amino acid permease, conserved site + Amino acid permease/ SLC12A domain Bcin14g01420 120 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Bcin14g01430 81 Effector(V1) Bcin14g01440 437 Helix-hairpin-helix motif + HhH-GPD domain + Endonuclease III-like, conserved site-2 + DNA glycosylase + Helix-turn-helix, base-excision DNA repair, C-terminal + Endonuclease III-like protein 1 Bcin14g01450 525 Amine oxidase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin14g01460 749 Bcin14g01470 384 Bcin14g01480 230 DSBA-like thioredoxin domain + Thioredoxin-like fold Bcin14g01490 295 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin14g01500 1426 Signaling pathway Bcpom1, Dual specificity protein kinase pom1 Bcin14g01510 508 Peroxin/Dysferlin domain Bcin14g01520 570 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin14g01530 512 Cytochrome b5-like heme/steroid binding domain + Acyl-CoA dehydrogenase, conserved site + Acyl-CoA oxidase/dehydrogenase, central domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase/oxidase, N-terminal + Cytochrome b5, heme-binding site Bcin14g01540 598 Adenosine/AMP deaminase domain + Metal-dependent hydrolase Bcin14g01550 2160 "Bcatg2, similar to yeast ATG2, Peripheral membrane protein required for autophagic vesicle formation; also required for vesicle formation during pexophagy and the cytoplasm-to-vaucole targeting (Cvt) pathway; involved in Atg9p cycling between the phagophore assembly site and mitochondria; essential for cell cycle progression from G2/M to G1 under nitrogen starvation; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000005186]" Bcin14g01560 169 Effector(V2)|Effector(V1) Zinc finger, AN1-type + Ubiquitin-like + Ubiquitin + Ubiquitin-related domain Bcin14g01570 455 Protein of unknown function DUF4246 Bcin14g01580 363 Effector(V2) Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin14g01590 1260 Bcrpb2, RNA polymeraseII second largest subunit Bcin14g01600 77 SignalP-noTM//Effector(V1) Protein Pet117, mitochondrial Bcin14g01610 119 "Bcvma10, similar to yeast VMA10, Subunit G of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; involved in vacuolar acidification; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits [Source:SGD;Acc:S000002100]" Bcin14g01620 379 "Bctgl2, similar to yeast TGL2, Triacylglycerol lipase that is localized to the mitochondria; has lipolytic activity towards triacylglycerols and diacylglycerols when expressed in E. coli [Source:SGD;Acc:S000002465]" Bcin14g01630 335 CAZy : PL1PCW pectin//SignalP-noTM//Early secretome Pectate lyase/Amb allergen + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin14g01640 431 Protein of unknown function DUF159 Bcin14g01650 673 Permease, cytosine/purines, uracil, thiamine, allantoin + Nucleobase cation symporter-1, NCS1 Bcin14g01660 336 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin14g01670 437 HTH CenpB-type DNA-binding domain + Homeodomain-like + Protein of unknown function DUF3425 Bcin14g01680 302 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin14g01690 411 CAZy : CBM1,GH5PCW/FCW //SignalP-noTM Cellulose-binding domain, fungal + Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Glycoside hydrolase, family 5, conserved site Bcin14g01700 457 CAZy : CBM1,GH6PCW cellulose//SignalP-noTM//Early secretome Cellulose-binding domain, fungal + Glycoside hydrolase, family 6, conserved site + 1, 4-beta cellobiohydrolase Bcin14g01710 316 CAZy : GT8 Glycosyl transferase, family 8 + Nucleotide-diphospho-sugar transferases Bcin14g01720 342 Transporter Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin14g01730 354 yes Signaling pathway Bcg2, Galpha subunit Bcin14g01740 292 Spermidine/spermine synthases + S-adenosyl-L-methionine-dependent methyltransferase + Polyamine biosynthesis domain, conserved site + Polyamine biosynthesis domain + Spermidine/spermine synthase, eukaryotes Bcin14g01750 298 "Bcnit3, similar to yeast NIT3, Nit protein; one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member [Source:SGD;Acc:S000004343]" Bcin14g01760 2100 Major facilitator superfamily domain Bcin14g01770 541 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin14g01780 170 Effector(V2)|Effector(V1) Bcin14g01790 488 Cys2His2 transcription factor CND13, CalciNeurine-Dependant (CND) gene, Cys2His2 transcription factor Bcin14g01800 354 "Bcrfc5, similar to yeast RFC5, Subunit of heteropentameric Replication factor C (RF-C); RF-C is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon [Source:SGD;Acc:S000000291]" Bcin14g01810 446 "Bclpl1, similar to yeast LPL1, Phospholipase; contains lipase specific GXSXG motif; maintains lipid droplet (LD) morphology; induced by transcription factor Rpn4p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005585]" Bcin14g01820 704 Ribonuclease H-like domain + Exonuclease, RNase T/DNA polymerase III Bcin14g01830 737 Zinc finger, CCHC-type Bcin14g01840 181 ORMDL family Bcin14g01850 462 SignalP-noTM Collagen triple helix repeat Bcin14g01860 326 Class II aldolase/adducin N-terminal Bcin14g01870 1184 yes Signaling pathway BcSln1, HHK5, Biosensor of HOG pathway, Histidine kinase - group VI Bcin14g01880 595 F-box domain + Leucine-rich repeat domain, L domain-like Bcin14g01890 407 "Bcbmt6, similar to yeast BMT6, Methyltransferase required for m3U2843 methylation of the 25S rRNA; S-adenosylmethionine-dependent; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR063W is not an essential gene [Source:SGD;Acc:S000004053]" Bcin14g01900 963 SignalP-noTM SAC domain + Inositol phosphatase Bcin14g01910 547 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin14g01920 331 "Bcmaf1, similar to yeast MAF1, Highly conserved negative regulator of RNA polymerase III; involved in tRNA processing and stability; inhibits tRNA degradation via rapid tRNA decay (RTD) pathway; binds N-terminal domain of Rpc160p subunit of Pol III to prevent closed-complex formation; localization and activity are regulated by phosphorylation, mediated by TORC1, protein kinase A, and Sch9p; localizes to cytoplasm during vegetative growth and translocates to nucleus and nucleolus under stress conditions [Source:SGD;Acc:S000002412]" Bcin14g01930 161 Effector(V1) "Bcaps1, similar to yeast APS1, Small subunit of the clathrin-associated adaptor complex AP-1; AP-1 is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex [Source:SGD;Acc:S000004160]" Bcin14g01940 316 NADP-dependent oxidoreductase domain + Glutamate--cysteine ligase regulatory subunit Bcin14g01950 269 "Bcbud32, similar to yeast BUD32, Protein kinase; component of the EKC/KEOPS complex with Kae1p, Cgi121p, Pcc1p, and Gon7p; Pyrococcus Bud32 ortholog functions as a P-loop ATPase rather than a protein kinase in the context of the complex; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription [Source:SGD;Acc:S000003494]" Bcin14g01960 265 Bcin14g01970 621 Bcin14g01980 685 Transketolase, N-terminal + Transketolase-like, pyrimidine-binding domain + Transketolase, bacterial-like + Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II + Transketolase binding site + Thiamin diphosphate-binding fold + Transketolase family + Transketolase, C-terminal domain Bcin14g01990 225 Bzip transcription factor Basic-leucine zipper domain Bcin14g02000 199 Effector(V1) Carboxymuconolactone decarboxylase-like + AhpD-like Bcin14g02010 160 Effector(V1) "Bcvma3, similar to yeast VMA3, Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase; dicyclohexylcarbodiimide binding subunit; required for vacuolar acidification and important for copper and iron metal ion homeostasis [Source:SGD;Acc:S000000753]" Bcin14g02020 128 Effector(V2)|Effector(V1) "Bcsnu13, similar to yeast SNU13, RNA binding protein; part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein [Source:SGD;Acc:S000000752]" Bcin14g02030 698 Acyl-CoA oxidase, C-terminal + Acyl-CoA oxidase/dehydrogenase, central domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA oxidase + Acyl-CoA dehydrogenase/oxidase, N-terminal + Acyl-coenzyme A oxidase, N-terminal Bcin14g02040 288 Effector(V2)|Effector(V1) Bcin14g02050 466 RGS domain Bcin14g02060 276 Bcin14g02070 299 Immunoglobulin E-set Bcin14g02080 532 Heterokaryon incompatibility Bcin14g02090 339 Glutathione S-transferase, C-terminal-like + Thioredoxin-like fold + Metaxin, glutathione S-transferase domain Bcin14g02100 722 "Bcvid30, similar to yeast VID30, Central component of GID Complex, involved in FBPase degradation; interacts strongly with Gid8p to serve as a scaffold for other GID Complex subunits; contains SPRY domain and 3 domains that are also found in Gid8p - LisH, CTLH, and CRA; required for association of Vid vesicles and actin patches in vacuole import and degradation pathway; shifts the balance of nitrogen metabolism toward glutamate production; localizes to the nucleus and the cytoplasm [Source:SGD;Acc:S000003196]" Bcin14g02110 303 INO80 complex, subunit Ies4 Bcin14g02120 456 "Bccue5, similar to yeast CUE5, Ubiquitin-binding protein; functions as a ubiquitin-Atg8p adaptor in ubiquitin-dependent autophagy; contains a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; GFP-fusion protein localizes to the cytoplasm in a punctate pattern; CUE5 has a paralog, DON1, that arose from the whole genome duplication; human TOLLIP is a functional CUE-domain homolog, rescuing hypersensitivity of cue5 null mutant cells to Htt-96Q [Source:SGD;Acc:S000005568]" Bcin14g02130 1016 "Bcpho81, similar to yeast PHO81, Cyclin-dependent kinase (CDK) inhibitor; regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003465]" Bcin14g02140 215 Effector(V1) Bcin14g02150 220 Effector(V2) "Bccoa1, similar to yeast COA1, Mitochondrial inner membrane protein; required for assembly of the cytochrome c oxidase complex (complex IV); interacts with complex IV assembly factor Shy1p during the early stages of assembly [Source:SGD;Acc:S000001419]" Bcin14g02160 312 "Bcmrpl9, similar to yeast MRPL9, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000003452]" Bcin14g02170 213 "Bcjlp2, similar to yeast JLP2, Protein of unknown function; contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein) [Source:SGD;Acc:S000004739]" Bcin14g02180 218 Galactose-binding domain-like + PITH domain Bcin14g02190 985 RNA polymerase I-specific transcription initiation factor RRN6-like Bcin14g02200 263 Chromosome segregation protein Spc25 Bcin14g02210 83 Effector(V1) Protein of unknown function DUF3743 Bcin14g02220 718 Zinc finger, RING-type + Rubredoxin-type fold + Zinc finger, CHY-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, CTCHY-type Bcin14g02230 127 Early secretome Bcin14g02240 351 Transporter Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin14g02250 901 Domain of unknown function DUF2293 Bcin14g02260 214 Snf7 family Bcin14g02270 781 AAA+ ATPase domain + ATPase, AAA-type, core + ATPase, AAA-type, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin14g02280 244 Bcin14g02290 1367 Nascent polypeptide-associated complex subunit alpha Bcin14g02300 231 Bcin14g02310 204 Effector(V1) Adenylate kinase/UMP-CMP kinase + P-loop containing nucleoside triphosphate hydrolase Bcin14g02320 160 Effector(V2)|Effector(V1) Bcin14g02330 309 "Bcrrp7, similar to yeast RRP7, Essential protein involved in rRNA processing and ribosome biogenesis; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000536]" Bcin14g02340 359 "Bcdmc1, similar to yeast DMC1, Meiosis-specific recombinase required for repair of double-strand breaks; also required for pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein; binds ssDNA and dsDNA, forms helical filaments; stimulated by Rdh54p [Source:SGD;Acc:S000000981]" Bcin14g02350 265 Bcin14g02360 540 "Bctrp2, similar to yeast TRP2, Anthranilate synthase; catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p [Source:SGD;Acc:S000000892]" Bcin14g02370 108 Effector(V2)|Effector(V1) Bccyc1, Cytochrome c Bcin14g02380 262 Bcin14g02390 377 "Bcrrp42, similar to yeast RRP42, Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp42p (EXOSC7) [Source:SGD;Acc:S000002269]" Bcin14g02400 339 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin14g02410 635 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin14g02420 147 Effector(V2)|Effector(V1) Bcin14g02430 517 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Glucose-methanol-choline oxidoreductase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin14g02440 489 HAD-superfamily hydrolase, subfamily IIA, CECR5 + HAD-superfamily hydrolase, subfamily IIA + HAD-like domain Bcin14g02450 354 Amidohydrolase 1 + Metal-dependent hydrolase Bcin14g02460 327 DapA-like + Aldolase-type TIM barrel + Schiff base-forming aldolase, conserved site Bcin14g02470 499 SignalP-noTM Carbohydrate-binding WSC + Domain of unknown function DUF1996 Bcin14g02480 381 "Bcerv41, similar to yeast ERV41, Protein localized to COPII-coated vesicles; forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) protein [Source:SGD;Acc:S000004532]" Bcin14g02490 331 Target SNARE coiled-coil domain + Syntaxin, N-terminal domain + t-SNARE Bcin14g02500 712 Heterokaryon incompatibility Bcin14g02510 581 yes SignalP-noTM//Early secretome Bclcc2, Laccase Bcin14g02520 298 "Bcimp4, similar to yeast IMP4, Component of the SSU processome; SSU processome is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs [Source:SGD;Acc:S000005019]" Bcin14g02530 1100 "Bcnam7, similar to yeast NAM7, ATP-dependent RNA helicase of the SFI superfamily; involved in nonsense mediated mRNA decay; required for efficient translation termination at nonsense codons and targeting of NMD substrates to P-bodies; binds to the small ribosomal subunit via an interaction with Rps26; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000004685]" Bcin14g02540 192 "Bcbet3, similar to yeast BET3, Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factors for the GTPase Ypt1, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII); hydrophilic homodimeric protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles [Source:SGD;Acc:S000001776]" Bcin14g02550 356 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat Bcin14g02560 379 Bcin14g02570 238 Bcin14g02580 227 Effector(V2)|Effector(V1) Zinc finger, CCHC-type Bcin14g02590 771 LIS1 homology motif Bcin14g02600 65 Bcin14g02610 1003 SH3 domain + Sterile alpha motif domain + Pleckstrin homology domain + Pleckstrin homology-like domain + Sterile alpha motif/pointed domain Bcin14g02620 1185 Zinc finger, MIZ-type Bcin14g02630 96 Bcin14g02640 563 General substrate transporter + Major facilitator superfamily domain Bcin14g02650 490 Arrestin-like, N-terminal + Immunoglobulin E-set Bcin14g02660 459 RNA recognition motif domain + Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + Nucleotide-binding alpha-beta plait domain + Cyclophilin-type peptidyl-prolyl cis-trans isomerase + Cyclophilin-like domain Bcin14g02670 492 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin14g02680 135 Ribosomal protein S24e + Nucleotide-binding alpha-beta plait domain + Ribosomal protein L23/L15e core domain + Ribosomal S24e conserved site Bcin14g02690 375 "Bcefm3, similar to yeast EFM3, S-adenosylmethionine-dependent methyltransferase; seven-beta-strand lysine methyltransferase which trimethylates translation elongation factor EF2 (Eft1p and Eft2p) at lysine 509; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; ortholog of human gene FAM86A [Source:SGD;Acc:S000003890]" Bcin14g02700 262 General transcription factor TFIIH, subunit Tfb6 Bcin14g02710 591 Armadillo-like helical + Beta-catenin-like protein 1, N-terminal + Armadillo-type fold Bcin14g02720 512 "Bcnfs1, similar to yeast NFS1, Cysteine desulfurase; involved in iron-sulfur cluster (Fe/S) biogenesis and in thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria [Source:SGD;Acc:S000000522]" Bcin14g02730 436 "Bcrvs167, similar to yeast RVS167, Actin-associated protein with roles in endocytosis and exocytosis; interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; recruited to bud tips by Gyl1p and Gyp5p during polarized growth; homolog of mammalian amphiphysin [Source:SGD;Acc:S000002796]" Bcin14g02740 751 F-box domain Bcin14g02750 522 Major facilitator superfamily + Major facilitator superfamily domain Bcin14g02760 357 DnaJ domain Bcin14g02770 323 "Bcrpa43, similar to yeast RPA43, RNA polymerase I subunit A43 [Source:SGD;Acc:S000005867]" Bcin14g02780 1584 Bcin14g02790 147 SignalP-TM//Effector(V1) Bcin14g02800 533 CAZy : GH51PCW hemicellulose or pectin Alpha-L-arabinofuranosidase, C-terminal + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin14g02810 521 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin14g02820 668 CAZy : GH16FCW Glycoside hydrolase, family 16 + Beta-glucan synthesis-associated, SKN1 + Concanavalin A-like lectin/glucanase domain Bcin14g02830 392 "Bcrpl3, similar to yeast RPL3, Ribosomal 60S subunit protein L3; homologous to mammalian ribosomal protein L3 and bacterial L3; plays an important role in function of eIF5B in stimulating 3' end processing of 18S rRNA in context of 80S ribosomes that have not yet engaged in translation; involved in replication and maintenance of killer double stranded RNA virus [Source:SGD;Acc:S000005589]" Bcin14g02840 136 Effector(V1) Bcin14g02850 161 Bcin14g02860 207 Bcin14g02870 576 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin14g02880 99 Bcin14g02890 281 Leucine-rich repeat domain, L domain-like Bcin14g02900 306 Bcin14g02910 71 TFIIH subunit TTDA/Tfb5 Bcin14g02920 251 "Bcmrpl16, similar to yeast MRPL16, Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L16 ribosomal protein; synthetically lethal with hac1 mutant suggesting a role in the maturation of secretory proteins [Source:SGD;Acc:S000000134]" Bcin14g02930 1069 "Bcrfc1, similar to yeast RFC1, Subunit of heteropentameric Replication factor C (RF-C); RF-C is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon [Source:SGD;Acc:S000005743]" Bcin14g02940 348 Potassium channel, voltage-dependent, beta subunit, KCNAB-related + NADP-dependent oxidoreductase domain Bcin14g02950 503 Zinc finger, CCHC-type + Zinc knuckle CX2CX4HX4C Bcin14g02960 283 Effector(V1) Crotonase superfamily + Crontonase, C-terminal + ClpP/crotonase-like domain Bcin14g02970 964 Isochorismatase-like + Oxoglutarate/iron-dependent dioxygenase + Glutathione S-transferase, C-terminal-like + Alpha-ketoglutarate-dependent dioxygenase AlkB-like Bcin14g02973 93 Effector(V2)|Effector(V1) Mitochondrial export protein Som1 Bcin14g02980 61 Effector(V1) Cytochrome c oxidase, subunit VIIa, fungal Bcin14g02990 326 Bromodomain transcription factor + Transcription factor TFIID, subunit 8, C-terminal Bcin14g03000 558 "Bcmgs1, similar to yeast MGS1, Protein with DNA-dependent ATPase and ssDNA annealing activities; involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP); forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000005162]" Bcin14g03010 316 yes Bcgbl1, Heterotrimeric Gbeta-like protein Bcin14g03020 198 Effector(V1) Bcin14g03030 90 Effector(V1) Bcin14g03040 463 "Bctub4, similar to yeast TUB4, Gamma-tubulin; involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004202]" Bcin14g03050 1084 Nucleoporin Nup85-like Bcin14g03060 489 Kinetochore-associated protein Dsn1/Mis13 Bcin14g03070 320 NAD(P)-binding domain Bcin14g03080 579 Bcin14g03090 931 Bcin14g03100 470 "Bcdbp5, similar to yeast DBP5, Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family; involved in mRNA export from the nucleus, remodeling messenger ribonucleoprotein particles (mRNPs), with ATPase activity stimulated by Gle1p, IP6 and Nup159p; involved in translation termination along with Sup45p (eRF1); role in the cellular response to heat stress [Source:SGD;Acc:S000005572]" Bcin14g03110 733 "Bcbzz1, similar to yeast BZZ1, SH3 domain protein implicated in regulating actin polymerization; able to recruit actin polymerization machinery through its SH3 domains; colocalizes with cortical actin patches and Las17p; interacts with type I myosins [Source:SGD;Acc:S000001156]" Bcin14g03120 105 Bcin14g03130 680 Bcin14g03140 133 SignalP-noTM//Effector(V2)|Effector(V1) Ribonuclease/ribotoxin Bcin14g03150 300 Protein of unknown function DUF3632 Bcin14g03160 215 Effector(V2)|Effector(V1) Bcgst5, Glutathione S-transferase Bcin14g03170 386 SignalP-noTM Amidohydrolase 1 + Metal-dependent hydrolase Bcin14g03180 238 Effector(V1) Actin cortical patch SUR7/pH-response regulator PalI Bcin14g03190 879 Bcin14g03200 494 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin14g03210 232 Effector(V2)|Effector(V1) Bcin14g03220 250 Bcin14g03230 148 Effector(V2)|Effector(V1) YjgF/Yer057p/UK114 family + Endoribonuclease L-PSP/chorismate mutase-like Bcin14g03240 464 FAD linked oxidase, N-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin14g03250 238 Bcin14g03260 266 Bcin14g03270 1430 Bcin14g03280 245 Bcin14g03290 280 Bcin14g03300 84 Effector(V1) Bcin14g03310 147 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin14g03320 112 SignalP-noTM Bcin14g03330 210 Bcin14g03340 653 Protease Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin14g03350 726 Bcin14g03360 687 Mediator complex, subunit Med1, metazoa/fungi Bcin14g03370 768 yes Signaling pathway Bcsnf1, Snf1-like protein kinase Bcin14g03380 245 Bcin14g03390 368 "Bcgln1, similar to yeast GLN1, Glutamine synthetase (GS); synthesizes glutamine from glutamate and ammonia; with Glt1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source and by amino acid limitation; forms filaments of back-to-back stacks of cylindrical homo-decamers at low pH, leading to enzymatic inactivation and storage during states of advanced cellular starvation; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000006239]" Bcin14g03400 219 SignalP-noTM//Effector(V2)|Effector(V1) "Bcerv25, similar to yeast ERV25, Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, [Source:SGD;Acc:S000004473]" Bcin14g03410 190 Effector(V1) Zinc finger, C2H2-type matrin + Zinc finger, U1-type + Zinc finger, U1-C type + U1 small nuclear ribonucleoprotein C Bcin14g03420 575 Bcin14g03430 392 yes CAZy : PL1PCW pectin//SignalP-noTM//Early secretome BcPLN1, pectin lyase Bcin14g03440 546 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin14g03450 585 Transporter Sugar/inositol transporter + General substrate transporter + Major facilitator superfamily domain Bcin14g03460 1818 Helicase, C-terminal + DEAD/DEAH box helicase domain + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin14g03470 489 Major facilitator superfamily + Major facilitator superfamily domain Bcin14g03480 239 ABC transporter-like + P-loop containing nucleoside triphosphate hydrolase Bcin14g03490 432 Mitochondrial biogenesis protein AIM24 + Tryptophan RNA-binding attenuator protein-like domain Bcin14g03500 334 "Bcsui3, similar to yeast SUI3, Beta subunit of the translation initiation factor eIF2; involved in the identification of the start codon; proposed to be involved in mRNA binding [Source:SGD;Acc:S000006158]" Bcin14g03510 117 Bcin14g03520 164 SignalP-TM Marvel domain Bcin14g03530 433 UbiA prenyltransferase family + 4-hydroxybenzoate polyprenyl transferase + UbiA prenyltransferase conserved site + 4-hydroxybenzoate octaprenyltransferase Bcin14g03540 1526 JmjC domain + Zinc-finger domain of monoamine-oxidase A repressor R1 Bcin14g03550 549 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin14g03560 183 Effector(V1) Bcin14g03570 910 Bcin14g03580 230 Bcin14g03590 183 Bcin14g03600 419 Oxysterol-binding protein + Oxysterol-binding protein, conserved site Bcin14g03610 175 Effector(V1) CsbD-like Bcin14g03630 190 "Bcypd1, similar to yeast YPD1, Osmotic stress-responsive phosphorelay intermediate sensor protein; phosphorylated by the plasma membrane sensor Sln1p in response to osmotic stress and then in turn phosphorylates the response regulators Ssk1p in the cytosol and Skn7p in the nucleus [Source:SGD;Acc:S000002394]" Bcin14g03640 281 RNA ligase/cyclic nucleotide phosphodiesterase + Protein kinase A anchor protein, nuclear localisation signal domain Bcin14g03650 527 Bcin14g03660 286 Bcin14g03670 528 Folylpolyglutamate synthetase + Mur ligase, C-terminal + Mur ligase, central + Folylpolyglutamate synthetase, conserved site + Folylpolyglutamate synthase, eukaryota Bcin14g03680 584 AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain Bcin14g03690 73 Bcin14g03700 230 GNAT domain + Acyl-CoA N-acyltransferase Bcin14g03710 360 Amino acid/polyamine transporter I Bcin14g03720 86 Effector(V2)|Effector(V1) Bcin14g03730 454 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger, C2H2-like Bcin14g03740 304 Cys2His2 transcription factor Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin14g03750 270 BTB/POZ-like + BTB/POZ fold Bcin14g03760 504 Tryptophan halogenase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin14g03770 274 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin14g03780 1906 B30.2/SPRY domain + Ankyrin repeat + SPRY domain + Concanavalin A-like lectin/glucanase domain + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin14g03790 568 "Bcdpl1, similar to yeast DPL1, Dihydrosphingosine phosphate lyase; regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs), degrades phosphorylated long chain bases, prefers C16 dihydrosphingosine-l-phosphate as a substrate [Source:SGD;Acc:S000002702]" Bcin14g03800 309 "Bcmnn11, similar to yeast MNN11, Subunit of a Golgi mannosyltransferase complex; this complex also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p [Source:SGD;Acc:S000003719]" Bcin14g03810 410 Mannose-6-phosphate isomerase, type I + RmlC-like cupin domain + RmlC-like jelly roll fold + Mannose-6-phosphate isomerase Bcin14g03820 348 Zinc finger, RING-CH-type + Zinc finger, RING/FYVE/PHD-type + E3 ubiquitin-protein ligase MARCH-like Bcin14g03830 279 Protease "Bcpre8, similar to yeast PRE8, Alpha 2 subunit of the 20S proteasome [Source:SGD;Acc:S000004557]" Bcin14g03840 340 Regulator of chromosome condensation, RCC1 + Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II Bcin14g03850 635 Heat shock protein 70 family Bcin14g03860 791 "Bcime2, similar to yeast IME2, Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p [Source:SGD;Acc:S000003642]" Bcin14g03870 331 Stc1 domain Bcin14g03880 710 Bcin14g03890 434 Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal Bcin14g03900 361 Bcin14g03910 1523 yes BcdcL2, Dicer-like gene Bcin14g03920 677 "Bcgsh1, similar to yeast GSH1, Gamma glutamylcysteine synthetase; catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003637]" Bcin14g03930 481 yes GATA zinc finger transcription factor//Signaling pathway Bcltf1, Light-responsive GATA-type transcription factor Bcin14g03940 999 Bcin14g03950 334 "Bcpgc1, similar to yeast PGC1, Phosphatidyl Glycerol phospholipase C; regulates the phosphatidylglycerol (PG) content via a phospholipase C-type degradation mechanism; contains glycerophosphodiester phosphodiesterase motifs [Source:SGD;Acc:S000006127]" Bcin14g03960 1085 Cys2His2 transcription factor Bcin14g03970 457 CAZy : GH72FCW //SignalP-noTM//Early secretome Glucanosyltransferase + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin14g03980 178 Effector(V1) Free Met sulfoxide reductase conserved site + GAF domain + GAF domain-like Bcin14g03990 224 Effector(V2) Bcgst15, Glutathione S-transferase Bcin14g04000 319 NAD(P)-binding domain Bcin14g04010 344 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin14g04020 334 Protein of unknown function DUF3425 Bcin14g04030 129 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin14g04040 361 SignalP-noTM Bcin14g04050 242 Translin + Translin, N-terminal + Translin, C-terminal + Translin Bcin14g04060 248 Effector(V1) "Bcgpi11, similar to yeast GPI11, ER membrane protein involved in a late step of GPI anchor assembly; involved in the addition of phosphoethanolamine to the multiply mannosylated glycosylphosphatidylinositol (GPI) intermediate; human PIG-Fp is a functional homolog [Source:SGD;Acc:S000002710]" Bcin14g04070 498 SET domain Bcin14g04080 879 Zn2/Cys6 + fungal trans transcription factor BcfacB, Zn2/Cys6 transcription factor Bcin14g04090 128 Effector(V2)|Effector(V1) SCP2 sterol-binding domain Bcin14g04100 121 Effector(V2)|Effector(V1) Ribosomal protein L22e Bcin14g04110 57 Effector(V1) Proteolipid membrane potential modulator Bcin14g04120 419 GTP binding domain + Uncharacterised GTP-binding protein, C-terminal + P-loop containing nucleoside triphosphate hydrolase + OBG-type guanine nucleotide-binding (G) domain Bcin14g04130 147 Effector(V1) Bcin14g04140 1600 "Bcnup2, similar to yeast NUP2, Nucleoporin involved in nucleocytoplasmic transport; binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels; also has a role in chromatin organization [Source:SGD;Acc:S000004327]" Bcin14g04150 115 Cytochrome P450 Bcin14g04160 535 Transporter Amino acid/polyamine transporter I Bcin14g04170 270 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin14g04180 440 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain + Mandelate racemase/muconate lactonizing enzyme, C-terminal + Enolase N-terminal domain-like + Enolase C-terminal domain-like Bcin14g04190 828 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin14g04200 553 F-box domain + Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Leucine-rich repeat domain, L domain-like Bcin14g04210 293 HAD-like domain Bcin14g04220 777 Afadin/alpha-actinin-binding Bcin14g04230 295 "Bcrpl5, similar to yeast RPL5, Ribosomal 60S subunit protein L5; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly [Source:SGD;Acc:S000006052]" Bcin14g04240 1182 Leucine-rich repeat domain, L domain-like Bcin14g04250 204 Bcin14g04260 285 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcgas2, Regulated by Bmp1 MAP kinase cascade Bcin14g04270 398 "Bcste2, similar to yeast STE2, Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells [Source:SGD;Acc:S000001868]" Bcin14g04280 963 Bcin14g04290 328 Thioredoxin-like fold + Peroxiredoxin-like FAM213/AAED1 Bcin14g04300 242 Effector(V2)|Effector(V1) Bcin14g04310 472 Bcin14g04320 493 Indoleamine 2,3-dioxygenase Bcin14g04330 577 "Bcstp22, similar to yeast STP22, Component of the ESCRT-I complex; ESCRT-I is involved in ubiquitin-dependent sorting of proteins into the endosome; prevents polyubiquitination of the arrestin-related protein Rim8p, thereby directing its monoubiquitination by Rsp5p; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype; [Source:SGD;Acc:S000000514]" Bcin14g04340 1035 "Bccyc8, similar to yeast CYC8, General transcriptional co-repressor; acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters; can form the prion [OCT+] [Source:SGD;Acc:S000000316]" Bcin14g04350 474 Bcin14g04380 629 WD40 repeat + LIS1 homology motif + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site Bcin14g04390 364 Protein of unknown function DUF1751, integral membrane, eukaryotic Bcin14g04400 555 Leucine-rich repeat domain, L domain-like Bcin14g04410 83 Effector(V2)|Effector(V1) Bcin14g04420 388 Protein of unknown function DUF4419 Bcin14g04430 458 Nucleotide-diphospho-sugar transferases + Transmembrane protein 246 Bcin14g04440 490 Bcin14g04450 334 Bcin14g04460 1613 YD repeat + Rhs repeat-associated core Bcin14g04470 550 Transporter Amino acid/polyamine transporter I + Amino acid permease, fungi + Amino acid permease, conserved site + Amino acid permease/ SLC12A domain Bcin14g04480 509 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin14g04490 859 Cys2His2 transcription factor Zinc finger, C2H2-like Bcin14g04500 492 Protein kinase domain + WW domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain Bcin14g04510 236 Bcin14g04520 295 Coatomer, epsilon subunit + Tetratricopeptide-like helical domain Bcin14g04530 331 Pyridoxal phosphate phosphatase-related + HAD-like domain Bcin14g04540 519 Aminotransferase, class-II, pyridoxal-phosphate binding site + Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin14g04550 1120 C2 domain + EF-hand domain + Phosphatidylserine decarboxylase-related + EF-hand domain pair + EF-Hand 1, calcium-binding site + Phosphatidylserine decarboxylase + Phosphatidylserine decarboxylase, prokaryotic type 2 Bcin14g04560 340 CAZy : CE16PCW hemicellulose//SignalP-noTM SGNH hydrolase-type esterase domain Bcin14g04570 1140 Transporter P-type ATPase + Cation-transporting P-type ATPase, N-terminal + Cation-transporting P-type ATPase, C-terminal + P-type ATPase, subfamily IID + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, transmembrane domain + P-type ATPase, cytoplasmic domain N Bcin14g04580 346 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain Bcin14g04590 169 Effector(V1) Plectin/S10, N-terminal Bcin14g04600 376 Sde2 N-terminal domain Bcin14g04610 496 Protease Peptidase M20 + Amidase, hydantoinase/carbamoylase + Peptidase M20, dimerisation domain Bcin14g04620 85 Effector(V2)|Effector(V1) "Bccox12, similar to yeast COX12, Subunit VIb of cytochrome c oxidase; cytochrome c oxidase is also known as respiratory Complex IV and is the terminal member of the mitochondrial inner membrane electron transport chain; required for assembly of cytochrome c oxidase but not required for activity after assembly; phosphorylated; easily released from the intermembrane space, suggesting a loose association with Complex IV [Source:SGD;Acc:S000004028]" Bcin14g04630 82 Bcpic2, Gene with maximal expression at Complete colonization Bcin14g04640 153 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain + Cyclophilin-type peptidyl-prolyl cis-trans isomerase Bcin14g04650 1267 yes Bcsec31, involved in protein secretion Bcin14g04660 326 GET complex subunit Get2/sif1 Bcin14g04670 100 Effector(V2)|Effector(V1) Bcin14g04680 146 Effector(V2)|Effector(V1) Bcin14g04690 419 "Bcate1, similar to yeast ATE1, Arginyl-tRNA-protein transferase; catalyzes post-translational conjugation of arginine to the amino termini of acceptor proteins which are then subject to degradation via the N-end rule pathway [Source:SGD;Acc:S000002985]" Bcin14g04700 157 "Bcddp1, similar to yeast DDP1, Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; high specificity for diadenosine hexa- and pentaphosphates; contains endopolyphosphatase activity with a high affinity for polyphosphates, an activity also observed for its human DIPP homologs; possesses mRNA decapping activity; nudix hydrolase family member; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005689]" Bcin14g04710 181 Effector(V1) "Bclsm1, similar to yeast LSM1, Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; also enters the nucleus and positively regulates transcription initiation; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; binds to mRNAs under glucose starvation, most often in the 3' UTR; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000003660]" Bcin14g04720 573 Bcin14g04730 978 Ras-like guanine nucleotide exchange factor, N-terminal + Ras guanine-nucleotide exchange factors catalytic domain + Ras guanine nucleotide exchange factor domain + P-loop containing nucleoside triphosphate hydrolase Bcin14g04740 308 Bcin14g04750 245 Effector(V1) Zinc finger, HIT-type Bcin14g04760 313 "Bcnfu1, similar to yeast NFU1, Protein involved in iron metabolism in mitochondria; similar to NifU, which is a protein required for the maturation of the Fe/S clusters of nitrogenase in nitrogen-fixing bacteria [Source:SGD;Acc:S000001523]" Bcin14g04770 875 PSP1, C-terminal Bcin14g04780 337 Bcin14g04790 203 Ribosomal protein L15e + Ribosomal protein L23/L15e core domain + Ribosomal protein L15e, conserved site + Ribosomal protein L15e core domain Bcin14g04800 1230 "Bchul4, similar to yeast HUL4, Protein with similarity to hect domain E3 ubiquitin-protein ligases; not essential for viability; found in association with Trf4 in TRAMP complex [Source:SGD;Acc:S000003797]" Bcin14g04810 198 Effector(V2)|Effector(V1) Ribosomal protein/NADH dehydrogenase domain + Thioredoxin-like fold Bcin14g04820 718 P-loop containing nucleoside triphosphate hydrolase Bcin14g04830 106 Effector(V1) Bcin14g04840 765 Bcin14g04850 224 Effector(V1) H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote + Ribosomal protein L7Ae conserved site + Ribosomal protein L7Ae/L30e/S12e/Gadd45 + 50S ribosomal protein L30e-like Bcin14g04860 105 Effector(V2)|Effector(V1) "Bcqcr8, similar to yeast QCR8, Subunit 8 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p [Source:SGD;Acc:S000003702]" Bcin14g04870 278 Protease//Effector(V1) "Bcphb1, similar to yeast PHB1, Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR) [Source:SGD;Acc:S000003364]" Bcin14g04880 560 Cytochrome P450 Bcin14g04890 229 Effector(V2)|Effector(V1) NAD(P)-binding domain Bcin14g04900 493 SM cluster DMATS2 (KE)//Protease Bcdmats2, Dimethylallyl tryptophan synthase Bcin14g04910 134 Bcin14g04920 421 Rhodanese-like domain + Protein of unknown function DUF3650 Bcin14g04930 342 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin14g04940 458 "Bcbna3, similar to yeast BNA3, Kynurenine aminotransferase; catalyzes formation of kynurenic acid from kynurenine; potential Cdc28p substrate [Source:SGD;Acc:S000003596]" Bcin14g04950 289 "Bcdsc3, similar to yeast DSC3, Subunit of the DSC ubiquitin ligase complex; protein of unknown function that localizes to the ER and vacuole lumen; overexpression affects endocytic protein trafficking; ortholog of fission yeast dsc3 [Source:SGD;Acc:S000005749]" Bcin14g04960 456 S-adenosyl-L-methionine-dependent methyltransferase Bcin14g04970 519 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin14g04980 224 Effector(V1) "Bcvti1, similar to yeast VTI1, Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and Pep12p; required for multiple vacuolar sorting pathways [Source:SGD;Acc:S000004810]" Bcin14g04990 554 Amine oxidase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin14g05000 298 Bcin14g05010 263 Effector(V2) "Bccox11, similar to yeast COX11, Protein required for delivery of copper to Cox1p; mitochondrial inner membrane protein; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p [Source:SGD;Acc:S000006053]" Bcin14g05020 211 Effector(V2)|Effector(V1) RmlC-like cupin domain + Cupin 2, conserved barrel + RmlC-like jelly roll fold Bcin14g05030 520 Bcin14g05040 446 Bcin14g05050 612 DNA-repair protein, UmuC-like + DNA polymerase, Y-family, little finger domain Bcin14g05060 1372 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead + 2Fe-2S ferredoxin-type domain + Molybdopterin dehydrogenase, FAD-binding + [2Fe-2S]-binding + CO dehydrogenase flavoprotein, C-terminal + 2Fe-2S ferredoxin, iron-sulphur binding site + Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding + Beta-grasp domain + Xanthine dehydrogenase, small subunit + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 + Aldehyde oxidase/xanthine dehydrogenase + Oxidoreductase, molybdopterin binding site Bcin14g05070 197 Effector(V1) Antibiotic biosynthesis monooxygenase-like domain + Dimeric alpha-beta barrel Bcin14g05080 1014 Tetratricopeptide-like helical domain + Meiosis specific protein Spo22/ZIP4/TEX11 Bcin14g05090 510 Zn2/Cys6 transcription factor "Bcrds2, similar to yeast RDS2, Transcription factor involved in regulating gluconeogenesis; also involved in the regulation of glyoxylate cycle genes; member of the zinc cluster family of proteins; confers resistance to ketoconazole [Source:SGD;Acc:S000006054]" Bcin14g05100 601 Centromere protein Q Bcin14g05110 1261 "Bcrrp12, similar to yeast RRP12, Protein required for export of the ribosomal subunits; associates with the RNA components of the pre-ribosomes; has a role in nuclear import in association with Pse1p; also plays a role in the cell cycle and the DNA damage response; contains HEAT-repeats [Source:SGD;Acc:S000005933]" Bcin14g05120 266 SignalP-noTM Bcin14g05130 190 Effector(V1) Kinetochore subunit NKP2 Bcin14g05150 329 "Bceaf3, similar to yeast EAF3, Component of the Rpd3S histone deacetylase complex; Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000006227]" Bcin14g05160 153 "Bcmrpl33, similar to yeast MRPL33, Mitochondrial ribosomal protein of the large subunit [Source:SGD;Acc:S000004899]" Bcin14g05170 756 "Bcsec6, similar to yeast SEC6, Essential 88kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion; anchors the assembled complex to sites of secretion; interacts with SM-like protein and SNARE regulator Sec1p and may recruit it to sites of secretion; interacts with Sec9p and inhibits formation of the t-SNARE complex between Sec9p and Sso1p [Source:SGD;Acc:S000001330]" Bcin14g05180 305 Bcin14g05190 233 Bcin14g05200 330 Bcin14g05210 226 Effector(V2) Ankyrin repeat-containing domain Bcin14g05220 506 SignalP-noTM SGNH hydrolase-type esterase domain Bcin14g05230 400 "Bcutp5, similar to yeast UTP5, Subunit of U3-containing Small Subunit (SSU) processome complex; involved in production of 18S rRNA and assembly of small ribosomal subunit [Source:SGD;Acc:S000002806]" Bcin14g05240 934 Bromodomain + Bromodomain, conserved site + NET domain Bcin14g05250 932 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin14g05260 322 Bcin14g05270 194 Bcin14g05280 296 Bcin14g05290 335 Bcin14g05300 304 Bcin14g05310 381 Bcin14g05320 366 Bcin14g05330 386 SignalP-noTM Intradiol ring-cleavage dioxygenase, C-terminal + Intradiol ring-cleavage dioxygenase, core Bcin14g05340 396 CAZy : CE9 //Protease N-acetylglucosamine-6-phosphate deacetylase + Amidohydrolase 1 + Metal-dependent hydrolase, composite domain + Metal-dependent hydrolase Bcin14g05350 1214 C2 domain Bcin14g05360 644 Transporter Bchex5, Similar to MFS sugar transporter Bcin14g05370 410 yes Zn2/Cys6 transcription factor Bcltf4, Light-responsive Zn2/Cys6 transcription factor Bcin14g05380 373 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin14g05390 239 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Extracellular membrane protein, CFEM domain Bcin14g05400 490 Pyruvate carboxyltransferase + Alpha-isopropylmalate/homocitrate synthase, conserved site + Homocitrate synthase, fungi/archaea + Aldolase-type TIM barrel Bcin14g05410 334 RTA-like protein Bcin14g05420 764 "Bcprm1, similar to yeast PRM1, Pheromone-regulated multispanning membrane protein; involved in membrane fusion during mating; predicted to have 5 transmembrane segments and a coiled coil domain; localizes to the shmoo tip; regulated by Ste12p [Source:SGD;Acc:S000005223]" Bcin14g05430 625 Domain of unknown function DUF1741 Bcin14g05440 245 Effector(V1) "Bcisa1, similar to yeast ISA1, Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa2p and possibly Iba57p; isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources; functional ortholog of bacterial A-type ISC proteins [Source:SGD;Acc:S000003950]" Bcin14g05450 195 Effector(V1) Dimeric alpha-beta barrel + Stress responsive alpha-beta barrel Bcin14g05460 452 Helix-loop-helix (HLH) transcription factor Myc-type, basic helix-loop-helix (bHLH) domain Bcin14g05470 489 Transmembrane protein 135 Bcin14g05480 398 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin14g05490 331 S-adenosyl-L-methionine-dependent methyltransferase Bcin14g05500 590 yes SignalP-noTM Bcgod1, Glucose oxidase Bcin14g05510 320 CAZy : GH62PCW hemicellulose or pectin//SignalP-noTM Glycoside hydrolase, family 62, arabinosidase + Glycosyl hydrolase, five-bladed beta-propellor domain Bcin14g05520 141 Bcin14g05530 316 SignalP-noTM "Bczps1, similar to yeast ZPS1, Putative GPI-anchored protein; transcription is induced under low-zinc conditions, as mediated by the Zap1p transcription factor, and at alkaline pH [Source:SGD;Acc:S000005514]" Bcin14g05540 556 Zinc/iron permease Bcin14g05550 352 Bcin14g05560 387 Protease Epoxide hydrolase-like + Epoxide hydrolase, N-terminal + Epoxide hydrolase + Alpha/Beta hydrolase fold Bcin14g05570 372 SignalP-noTM Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin14g05580 499 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin15g00010 447 Bcin15g00020 221 Bcin15g00030 188 Outer membrane protein/outer membrane enzyme PagP, beta-barrel + Uncharacterised protein family UPF0311 Bcin15g00040 466 Major facilitator superfamily + Major facilitator superfamily domain Bcin15g00050 466 "Bcayt1, similar to yeast AYT1, Acetyltransferase; catalyzes trichothecene 3-O-acetylation, suggesting a possible role in trichothecene biosynthesis [Source:SGD;Acc:S000003986]" Bcin15g00060 243 Glutathione S-transferase, N-terminal + Glutathione S-transferase, C-terminal + Glutathione S-transferase, C-terminal-like + Thioredoxin-like fold Bcin15g00070 306 SsuA/THI5-like + NMT1/THI5 family Bcin15g00080 691 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin15g00090 494 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin15g00100 187 yes SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Bcieb1, Small secreted glycoprotein similar to IgE Binding proteins Bcin15g00110 48 Effector(V2) Bcin15g00120 783 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin15g00130 239 CAZy : CE5,CBM1PCW hemicellulose//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Cutinase + Alpha/Beta hydrolase fold Bcin15g00140 495 FAD binding domain + Flavocytochrome c + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain + Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Bcin15g00150 95 Effector(V2)|Effector(V1) Bcin15g00160 91 Bcin15g00170 395 SignalP-noTM Quinoprotein amine dehydrogenase, beta chain-like + WD40/YVTN repeat-like-containing domain Bcin15g00180 140 Effector(V2)|Effector(V1) Bcin15g00190 310 Phospholipid/glycerol acyltransferase + Acyltransferase, C-terminal domain Bcin15g00200 378 Bzip transcription factor Basic-leucine zipper domain + Yap1 redox domain Bcin15g00210 324 Kynurenine formamidase Bcin15g00220 621 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin15g00230 335 Protease Alpha/beta hydrolase fold-1 + Epoxide hydrolase-like + Alpha/Beta hydrolase fold Bcin15g00240 471 SignalP-noTM Bcin15g00250 62 Effector(V2)|Effector(V1) Bcin15g00260 529 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin15g00270 570 yes Transporter BcmfsM2, Similar to MFS multidrug transporter Bcin15g00280 1973 yes Bcrim15, Protein kinase involved in cell proliferation in response to nutrients Bcin15g00290 111 Effector(V2)|Effector(V1) Bcin15g00300 415 Bcin15g00310 371 3-beta hydroxysteroid dehydrogenase/isomerase + NAD(P)-binding domain Bcin15g00320 260 Globin, structural domain Bcin15g00330 717 Bcin15g00340 146 Effector(V1) "Bcrpb4, similar to yeast RPB4, RNA polymerase II subunit B32; forms dissociable heterodimer with Rpb7p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNAPII complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation [Source:SGD;Acc:S000003676]" Bcin15g00350 175 Effector(V2)|Effector(V1) "Bctrs23, similar to yeast TRS23, Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII); human homolog is TRAPPC4 [Source:SGD;Acc:S000002654]" Bcin15g00360 295 "Bcrpn10, similar to yeast RPN10, Non-ATPase base subunit of the 19S RP of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the regulatory particle (RP); binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein [Source:SGD;Acc:S000001243]" Bcin15g00370 268 Borealin-like, N-terminal Bcin15g00380 197 Effector(V1) "Bctma22, similar to yeast TMA22, Protein of unknown function; associates with ribosomes and has a putative RNA binding domain; interacts with Tma20p; similar to human GRAP and human DRP1, which interacts with human Tma20p homolog MCT-1; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003775]" Bcin15g00390 445 Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like Bcin15g00400 248 Effector(V1) Small GTPase superfamily + Small GTP-binding protein domain + P-loop containing nucleoside triphosphate hydrolase Bcin15g00410 753 Choline transporter-like Bcin15g00420 169 Effector(V1) Bcin15g00430 899 Ankyrin repeat + NACHT nucleoside triphosphatase + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin15g00440 491 Zinc finger, ZZ-type Bcin15g00450 1530 yes BcDIM2, Deficient in Methylation Bcin15g00460 500 Bcin15g00470 519 "Bccmr1, similar to yeast CMR1, DNA-binding protein with preference for UV-damaged DNA; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; potential regulatory target of Mbp1p, which binds to the promoter region; co-localizes with Hos2p in nuclear foci in response to DNA damage by MMS [Source:SGD;Acc:S000002315]" Bcin15g00480 1443 CAZy : GT1 Pleckstrin homology domain + UDP-glucuronosyl/UDP-glucosyltransferase + GRAM domain + Glycosyltransferase family 28, N-terminal domain + Pleckstrin homology-like domain Bcin15g00490 832 "Bcfcp1, similar to yeast FCP1, Carboxy-terminal domain (CTD) phosphatase; essential for dephosphorylation of the repeated C-terminal domain of the RNA polymerase II large subunit (Rpo21p); relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000004890]" Bcin15g00500 120 Effector(V2)|Effector(V1) GRIM-19 Bcin15g00510 169 Effector(V2)|Effector(V1) "Bccdd1, similar to yeast CDD1, Cytidine deaminase; catalyzes the modification of cytidine to uridine in vitro but native RNA substrates have not been identified, localizes to both the nucleus and cytoplasm [Source:SGD;Acc:S000004235]" Bcin15g00520 81 yes BcekdA,Bcest, Esterase Bcin15g00530 220 Effector(V2)|Effector(V1) Cytochrome P450 Bcin15g00540 135 Bcin15g00550 210 Effector(V2)|Effector(V1) HotDog domain Bcin15g00560 94 Effector(V1) Bcin15g00570 520 PIN domain-like Bcin15g00580 699 Bclox15741, Lipoxygenase Bcin15g00590 825 "Bcvid27, similar to yeast VID27, Cytoplasmic protein of unknown function; possibly involved in vacuolar protein degradation; not essential for proteasome-dependent degradation of fructose-1,6-bisphosphatase (FBPase); null mutants exhibit normal growth [Source:SGD;Acc:S000005156]" Bcin15g00600 180 Effector(V2)|Effector(V1) Ribosomal protein S17 + Nucleic acid-binding, OB-fold + Ribosomal protein S17, bacterial-type Bcin15g00610 895 AAA+ ATPase domain + ATPase, AAA-type, core + ATPase, AAA-type, conserved site + Vps4 oligomerisation, C-terminal + P-loop containing nucleoside triphosphate hydrolase Bcin15g00620 373 CAZy : GT25 Bcin15g00630 328 Bcin15g00640 690 "Bccog6, similar to yeast COG6, Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments [Source:SGD;Acc:S000004986]" Bcin15g00650 936 "Bcatg9, similar to yeast ATG9, Transmembrane protein involved in forming Cvt and autophagic vesicles; cycles between the phagophore assembly site (PAS) and other cytosolic punctate structures, not found in autophagosomes; may be involved in membrane delivery to the PAS [Source:SGD;Acc:S000002308]" Bcin15g00660 309 S-adenosyl-L-methionine-dependent methyltransferase Bcin15g00670 312 Transporter//Effector(V2) Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin15g00680 170 Bcin15g00690 213 Effector(V1) Bcin15g00700 279 Bcin15g00710 445 Bcin15g00720 446 Bcin15g00730 499 SignalP-noTM Cytochrome P450 + Cytochrome P450, E-class, group IV Bcin15g00740 79 Uncharacterised protein family YNL211C Bcin15g00750 474 Protein-tyrosine phosphatase, receptor/non-receptor type + Protein-tyrosine/Dual specificity phosphatase + Protein-tyrosine phosphatase, catalytic + Protein-tyrosine phosphatase, active site + Protein-tyrosine phosphatase-like Bcin15g00760 266 Membrane fusion mating protein FIG1 + Cell fusion protein Dni1/Fig1 Bcin15g00770 536 DNA replication/checkpoint protein Bcin15g00780 418 Bcin15g00790 202 Bcin15g00800 120 SignalP-noTM Bcin15g00810 292 SignalP-noTM Carbohydrate-binding WSC + Concanavalin A-like lectin/glucanase domain Bcin15g00820 373 "Bcaim24, similar to yeast AIM24, Protein with a role in determining mitochondrial architecture; inner membrane protein that interacts physically and genetically with the MICOS complex and is required for its integrity [Source:SGD;Acc:S000003841]" Bcin15g00830 715 Transporter "Bcatm1, similar to yeast ATM1, Mitochondrial inner membrane ATP-binding cassette (ABC) transporter; exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol [Source:SGD;Acc:S000004916]" Bcin15g00840 124 Bcin15g00850 696 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site + Calcium/calmodulin-dependent/calcium-dependent protein kinase Bcin15g00860 572 SignalP-TM Prenylcysteine lyase + Prenylcysteine oxidase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin15g00870 540 "Bccct6, similar to yeast CCT6, Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif [Source:SGD;Acc:S000002596]" Bcin15g00880 996 CAZy : GH47 Glycoside hydrolase, family 47 Bcin15g00890 224 Effector(V2)|Effector(V1) Cytochrome P450 Bcin15g00900 239 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin15g00910 76 Effector(V1) Bcin15g00920 1099 AMP-dependent synthetase/ligase + Acyl carrier protein-like + Male sterility, NAD-binding + NAD(P)-binding domain + AMP-binding, conserved site Bcin15g00930 423 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin15g00940 216 Bcin15g00950 248 Effector(V1) "Bcavo2, similar to yeast AVO2, Component of a complex containing the Tor2p kinase and other proteins; complex may have a role in regulation of cell growth [Source:SGD;Acc:S000004672]" Bcin15g00960 291 Bcin15g00970 951 "Bcchl1, similar to yeast CHL1, Probable DNA helicase; involved in sister-chromatid cohesion and genome integrity and interstrand cross-link repair; interacts with ECO1 and CTF18; mutants are defective in silencing, rDNA recombination, aging and the heat shock response; FANCJ-like helicase family member; mutations in the human homolog, DDX11/ChLR1, cause Warsaw breakage syndrome [Source:SGD;Acc:S000005929]" Bcin15g00980 277 "Bcrpn12, similar to yeast RPN12, Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001948]" Bcin15g00990 612 "Bclee1, similar to yeast LEE1, Zinc-finger protein of unknown function [Source:SGD;Acc:S000005975]" Bcin15g01000 438 F-box domain Bcin15g01010 320 Tat binding protein 1-interacting + Winged helix-turn-helix DNA-binding domain Bcin15g01020 839 Effector(V2)|Effector(V1) Sel1-like + Tetratricopeptide-like helical domain Bcin15g01030 354 CAZy : CE1,CBM1PCW hemicellulose//Protease//SignalP-noTM//Early secretome Cellulose-binding domain, fungal + Esterase, PHB depolymerase + Alpha/Beta hydrolase fold Bcin15g01040 138 Effector(V1) Bcin15g01050 508 Protease//SignalP-noTM//Early secretome "Bcape3, similar to yeast APE3, Vacuolar aminopeptidase Y; processed to mature form by Prb1p [Source:SGD;Acc:S000000490]" Bcin15g01060 1170 PAS domain + PAS-associated, C-terminal + PAC motif + Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily + PAS fold-3 Bcin15g01070 121 Effector(V2)|Effector(V1) Cytochrome c oxidase, subunit VIb Bcin15g01080 292 5-formyltetrahydrofolate cyclo-ligase + 5-formyltetrahydrofolate cyclo-ligase-like domain Bcin15g01090 261 Acyl-CoA N-acyltransferase Bcin15g01100 489 CAZy : GT71 Alpha-mannosyltransferase + Nucleotide-diphospho-sugar transferases Bcin15g01110 385 SignalP-noTM Bcin15g01120 554 Early secretome "Bcatp1, similar to yeast ATP1, Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase; which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; F1 translationally regulates ATP6 and ATP8 expression to achieve a balanced output of ATP synthase genes encoded in nucleus and mitochondria; phosphorylated; N-terminally propionylated in vivo [Source:SGD;Acc:S000000195]" Bcin15g01130 529 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase + Aldolase-type TIM barrel Bcin15g01140 557 Bcin15g01150 1478 SignalP-noTM VPS10 + Sortilin, C-terminal + Sortilin, N-terminal Bcin15g01160 936 GAF domain-like Bcin15g01170 845 CAZy : AA8,AA3,CBM1 //SignalP-noTM Glucose-methanol-choline oxidoreductase, N-terminal + Cellulose-binding domain, fungal + Glucose-methanol-choline oxidoreductase, C-terminal + Cellobiose dehydrogenase, cytochrome domain + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin15g01180 647 Fumarate reductase/succinate dehydrogenase, FAD-binding site + FAD binding domain + Succinate dehydrogenase, flavoprotein subunit + Succinate dehydrogenase/fumarate reductase, flavoprotein subunit + Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain + Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain + Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Bcin15g01190 533 Bcin15g01200 680 AAA+ ATPase domain + ATPase, AAA-type, core + ATPase, AAA-type, conserved site + BCS1, N-terminal + P-loop containing nucleoside triphosphate hydrolase Bcin15g01210 244 "Bctlg1, similar to yeast TLG1, Essential t-SNARE that mediates fusion of vesicles with the late Golgi; forms a complex with Tlg2p and Vti1p; mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p [Source:SGD;Acc:S000002876]" Bcin15g01220 722 "Bcrts1, similar to yeast RTS1, B-type regulatory subunit of protein phosphatase 2A (PP2A); Rts1p and Cdc55p are alternative regulatory subunits for PP2A catalytic subunits, Pph21p and Pph22p; PP2A-Rts1p protects cohesin when recruited by Sgo1p to the pericentromere; highly enriched at centromeres in the absence of Cdc55p; required for maintenance of septin ring organization during cytokinesis, for ring disassembly in G1 and for dephosphorylation of septin, Shs1p; homolog of the mammalian B' subunit of PP2A [Source:SGD;Acc:S000005540]" Bcin15g01230 718 "Bctfc1, similar to yeast TFC1, Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; human homolog is TFIIIC-63 [Source:SGD;Acc:S000000327]" Bcin15g01240 483 "Bccdc55, similar to yeast CDC55, Non-essential regulatory subunit B of protein phosphatase 2A (PP2A); localization to cytoplasm requires Zds1p and Zds2p and promotes mitotic entry; localization to nucleus prevents mitotic exit; required for correct nuclear division and chromosome segregation in meiosis; maintains nucleolar sequestration of Cdc14p during early meiosis; limits formation of PP2A-Rts1p holocomplexes to ensure timely dissolution of sister chromosome cohesion; homolog of mammalian B55 [Source:SGD;Acc:S000003158]" Bcin15g01250 66 Effector(V1) "Bcnop10, similar to yeast NOP10, Subunit of box H/ACA snoRNP complex; required for pseudouridylation and processing of pre-18S rRNA [Source:SGD;Acc:S000007455]" Bcin15g01260 458 "Bcnob1, similar to yeast NOB1, Protein involved in proteasomal and 40S ribosomal subunit biogenesis; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA; cleavage is activated by Fun12p, a GTPase and translation initiation factor; relocalizes from nucleus to nucleolus upon DNA replication stress [Source:SGD;Acc:S000005582]" Bcin15g01270 396 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin15g01280 612 SET domain + Zinc finger, MYND-type Bcin15g01290 334 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin15g01300 648 "Bcpex5, similar to yeast PEX5, Peroxisomal membrane signal receptor for peroxisomal matrix proteins; receptor for the C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins; required for peroxisomal matrix protein import; also proposed to have PTS1-receptor independent functions [Source:SGD;Acc:S000002652]" Bcin15g01310 909 Bcin15g01320 753 Ribonuclease H-like domain + Exonuclease, RNase T/DNA polymerase III Bcin15g01330 912 yes Signaling pathway BcPtpA, Protein Tyrosine Phosphatase Bcin15g01340 507 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin15g01350 886 "Bcsey1, similar to yeast SEY1, Dynamin-like GTPase that mediates homotypic ER fusion; has a role in ER morphology; interacts physically and genetically with Yop1p and Rtn1p; functional ortholog of the human atlastin ATL1, defects in which cause a form of the human disease hereditary spastic paraplegia; homolog of Arabidopsis RHD3 [Source:SGD;Acc:S000005691]" Bcin15g01360 529 Transporter "Bctpo5, similar to yeast TPO5, Protein involved in excretion of putrescine and spermidine; putative polyamine transporter in the Golgi or post-Golgi vesicles [Source:SGD;Acc:S000001657]" Bcin15g01370 317 Bcin15g01380 445 "Bclsc2, similar to yeast LSC2, Beta subunit of succinyl-CoA ligase; succinyl-CoA ligase is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate [Source:SGD;Acc:S000003476]" Bcin15g01390 777 Bcin15g01400 246 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin15g01410 416 Bcin15g01420 198 Effector(V1) Ubiquitin system component Cue + UBA-like Bcin15g01430 578 Bcin15g01440 418 "Bccdc73, similar to yeast CDC73, Component of the Paf1p complex; binds to and modulates the activity of RNA polymerases I and II; required for expression of certain genes, modification of some histones, and telomere maintenance; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay; protein abundance increases in response to DNA replication stress; human homologue, parafibromin, is a tumour suppressor linked to breast, renal and gastric cancers [Source:SGD;Acc:S000004410]" Bcin15g01450 693 Bcin15g01460 418 WD40 repeat + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin15g01470 474 "Bcalg7, similar to yeast ALG7, UDP-N-acetyl-glucosamine-1-P transferase; transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first step of the dolichol pathway of protein asparagine-linked glycosylation; inhibited by tunicamycin [Source:SGD;Acc:S000000447]" Bcin15g01480 985 SET domain + Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type Bcin15g01490 274 yes Bcebdp1, Emopamil-binding protein Bcin15g01500 1209 "Bclrg1, similar to yeast LRG1, GTPase-activating protein (GAP); contains Rho1p-specific GAP activity, interacting with activated forms of Rho1p; functions along with Sac7p as a negative regulator of the Pkc1p-mediated cell wall integrity signaling pathway; negative regulator of cell wall 1,3-beta-glucan biosynthesis; required for efficient cell fusion; contains a RhoGAP domain and three Lin-11-Isl1-Mec-3 (LIM) domains [Source:SGD;Acc:S000002399]" Bcin15g01510 481 Bcin15g01520 233 Effector(V2)|Effector(V1) "Bcspc2, similar to yeast SPC2, Subunit of signal peptidase complex; complex catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC25; other members of the complex are Spc1p, Spc1p, and Sec11p [Source:SGD;Acc:S000004519]" Bcin15g01530 261 "Bcemc3, similar to yeast EMC3, Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; required for respiratory growth; null mutant displays induction of the unfolded protein response; homologous to worm Y62E10A.10/EMC-3, fly CG6750, human TMEM111 [Source:SGD;Acc:S000001690]" Bcin15g01540 333 BTB/POZ-like + BTB/POZ fold Bcin15g01550 325 "Bcrpf2, similar to yeast RPF2, Essential protein involved in rRNA maturation and ribosomal assembly; involved in the processing of pre-rRNA and the assembly of the 60S ribosomal subunit; interacts with ribosomal protein L11; localizes predominantly to the nucleolus; constituent of 66S pre-ribosomal particles [Source:SGD;Acc:S000001789]" Bcin15g01560 223 Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 + Peroxisomal membrane protein 4 Bcin15g01570 921 Protease Peptidase S9, prolyl oligopeptidase, catalytic domain + Peptidase S9B, dipeptidylpeptidase IV N-terminal + Alpha/Beta hydrolase fold Bcin15g01580 397 Bcin15g01590 577 Transporter BcXyn11B, Xylanase of family GH11 (Garcia et al., 2017) Bcin15g01600 222 CAZy : GH11PCW hemicellulose//SignalP-noTM Glycoside hydrolase, family 11 + Glycoside hydrolase, family 11/12 + Concanavalin A-like lectin/glucanase domain + Glycosyl hydrolases family 11 (GH11) domain Bcin15g01610 1111 "Bcmet18, similar to yeast MET18, Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at a late step of Fe-S cluster assembly; forms the CIA targeting complex with Cia1p and Cia2p that directs Fe-S cluster incorporation into a subset of proteins involved in methionine biosynthesis, DNA replication and repair, transcription, and telomere maintenance; ortholog of human MMS19 [Source:SGD;Acc:S000001390]" Bcin15g01620 326 "Bcmtd1, similar to yeast MTD1, NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase; plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline [Source:SGD;Acc:S000001788]" Bcin15g01630 142 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein + Membrane associated eicosanoid/glutathione metabolism-like domain Bcin15g01640 729 Pleckstrin homology domain + Engulfment/cell motility, ELMO + Armadillo-like helical + Armadillo-type fold + Domain of unknown function DUF3361 Bcin15g01650 388 Bcin15g01660 322 Transporter "Bctpc1, similar to yeast TPC1, Mitochondrial membrane transporter; mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family [Source:SGD;Acc:S000003328]" Bcin15g01670 493 "Bcaim17, similar to yeast AIM17, Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss [Source:SGD;Acc:S000001013]" Bcin15g01680 172 Effector(V2)|Effector(V1) Bcscd2, Scytalone dehydratase, involved in DHN melanin biosynthesis Bcin15g01690 306 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin15g01700 548 Transporter//Effector(V2)|Effector(V1) Fungal trichothecene efflux pump + Major facilitator superfamily domain + Major facilitator superfamily Bcin15g01710 708 CAZy : GH71,CBM24,CBM24,CBM24,CBM24FCW //SignalP-noTM Glycoside hydrolase, family 71 Bcin15g01720 395 Bcin15g01730 449 SignalP-noTM Cupredoxin Bcin15g01740 601 CAZy : GT57 "Bcalg6, similar to yeast ALG6, Alpha 1,3 glucosyltransferase; involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; mutations in human ortholog are associated with disease [Source:SGD;Acc:S000005528]" Bcin15g01750 99 Effector(V1) Bcin15g01760 222 Effector(V1) Bcin15g01770 163 Effector(V1) Bcin15g01780 293 Bcin15g01790 332 Bcin15g01800 398 Bcin15g01810 197 "Bcmpo1, similar to yeast MPO1, Protein involved in metabolism of phytosphingosine; not an essential gene [Source:SGD;Acc:S000002978]" Bcin15g01820 172 Effector(V2)|Effector(V1) "Bcrpb7, similar to yeast RPB7, RNA polymerase II subunit B16; forms dissociable heterodimer with Rpb4p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNA polymerase II complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation [Source:SGD;Acc:S000002812]" Bcin15g01830 329 Bcin15g01840 1243 Putative amidoligase enzyme Bcin15g01850 234 Effector(V1) SH3-binding, glutamic acid-rich protein + Thioredoxin-like fold Bcin15g01860 507 Thiamine pyrophosphate enzyme, C-terminal TPP-binding + Thiamine pyrophosphate enzyme, central domain + Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain + DHS-like NAD/FAD-binding domain + Thiamin diphosphate-binding fold Bcin15g01870 410 Bcin15g01880 626 Ankyrin repeat + Ankyrin repeat-containing domain Bcin15g01890 2067 Bcin15g01900 849 Cys2His2 transcription factor Bcace1, Cys2His2 transcription factor Bcin15g01910 218 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin15g01920 275 Bcin15g01930 628 Bcin15g01940 157 Effector(V2) Bcin15g01950 304 Protein of unknown function DUF3328 Bcin15g01960 212 SignalP-noTM Bcin15g01970 204 Effector(V2)|Effector(V1) Bcin15g01980 277 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin15g01990 230 SignalP-noTM//Early secretome Cupredoxin Bcin15g02000 405 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin15g02010 507 "Bcorc5, similar to yeast ORC5, Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing [Source:SGD;Acc:S000005205]" Bcin15g02020 567 Bcin15g02030 588 "Bccus1, similar to yeast CUS1, Protein required for assembly of U2 snRNP into the spliceosome; forms a complex with Hsh49p and Hsh155p [Source:SGD;Acc:S000004853]" Bcin15g02040 571 Triose-phosphate transporter domain Bcin15g02050 836 Leucine-rich repeat domain, L domain-like Bcin15g02060 854 Zn2/Cys6 transcription factor Polycomb protein, VEFS-Box + Zinc finger, PHD-type, conserved site Bcin15g02070 909 Bcin15g02080 509 "Bcatp2, similar to yeast ATP2, Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase; which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; F1 translationally regulates ATP6 and ATP8 expression to achieve a balanced output of ATP synthase genes encoded in nucleus and mitochondria; phosphorylated [Source:SGD;Acc:S000003882]" Bcin15g02090 700 CAZy : CBM48,GH13Energy "Bcglc3, similar to yeast GLC3, Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000000737]" Bcin15g02100 612 "Bcmcx1, similar to yeast MCX1, Mitochondrial matrix protein; putative ATP-binding chaperone with non-proteolytic function; similar to bacterial ClpX proteins [Source:SGD;Acc:S000000431]" Bcin15g02110 165 Effector(V2)|Effector(V1) Cytochrome c oxidase subunit IV family Bcin15g02120 338 Effector(V2) Glyceraldehyde-3-phosphate dehydrogenase, type I + NAD(P)-binding domain + Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain + Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain + Glyceraldehyde 3-phosphate dehydrogenase, active site + Glyceraldehyde/Erythrose phosphate dehydrogenase family Bcin15g02130 796 yes Bchda1, histone deacetylase Bcin15g02140 368 F-box domain Bcin15g02150 1148 PAS domain + PAS-associated, C-terminal + Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily + PAS fold-4 Bcin15g02160 373 Bcin15g02170 185 Bcin15g02180 1594 WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain Bcin15g02190 151 Effector(V1) Bladder cancer-related BC10 Bcin15g02200 321 SignalP-noTM LicD + Fukutin-related Bcin15g02210 296 Bcin15g02220 264 Bcin15g02230 189 Effector(V2)|Effector(V1) Bcin15g02240 340 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin15g02260 87 Bcin15g02270 714 CAZy : GT3 Glycogen synthase Bcin15g02280 403 Bcin15g02290 499 Zinc finger, CCHC-type Bcin15g02300 573 Bcin15g02310 463 NmrA-like domain + NAD(P)-binding domain Bcin15g02320 556 SignalP-noTM Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin15g02330 834 Bcin15g02340 339 Translation Initiation factor eIF- 4e + Eukaryotic translation initiation factor 4E (eIF-4E), conserved site + Translation Initiation factor eIF- 4e-like domain Bcin15g02350 464 "Bcfmo1, similar to yeast FMO1, Flavin-containing monooxygenase; localized to the cytoplasmic face of the ER membrane; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins [Source:SGD;Acc:S000001219]" Bcin15g02360 1763 Telomeric single stranded DNA binding POT1/Cdc13 + Nucleic acid-binding, OB-fold Bcin15g02370 800 Ankyrin repeat + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin15g02380 257 Protease//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome Bcacp1, Pepstatin-insensitive aspartic protease Bcin15g02390 225 SignalP-noTM//Effector(V1) Bcin15g02400 385 "Bcbas1, similar to yeast BAS1, Myb-related transcription factor; involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes [Source:SGD;Acc:S000001807]" Bcin15g02410 677 SignalP-noTM Bcin15g02420 276 NTF2-like domain Bcin15g02430 488 Oxoglutarate/iron-dependent dioxygenase + Prolyl 4-hydroxylase, alpha subunit Bcin15g02440 824 CAZy : GH3,CBM1PCW/FCW //SignalP-noTM Cellulose-binding domain, fungal + Glycoside hydrolase, family 3, N-terminal + Glycoside hydrolase family 3 C-terminal domain + Glycoside hydrolase superfamily + Fibronectin type III-like domain Bcin15g02450 327 Anaphase-promoting complex, subunit 15/MND2 Bcin15g02460 2140 Protease "Bcglt1, similar to yeast GLT1, NAD(+)-dependent glutamate synthase (GOGAT); synthesizes glutamate from glutamine and alpha-ketoglutarate; with Gln1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source; assembles into filaments as cells approach stationary phase and under cytosolic acidification and starvation conditions [Source:SGD;Acc:S000002330]" Bcin15g02470 773 Domain of unknown function DUF202 + SPX, N-terminal + VTC domain Bcin15g02480 837 Bcin15g02490 177 Effector(V2)|Effector(V1) "Bcbet1, similar to yeast BET1, Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins [Source:SGD;Acc:S000001266]" Bcin15g02500 111 Histone chaperone domain CHZ Bcin15g02510 1132 "Bcamd1, similar to yeast AMD1, AMP deaminase; tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; thought to be involved in regulation of intracellular purine (adenine, guanine, and inosine) nucleotide pools [Source:SGD;Acc:S000004498]" Bcin15g02520 792 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin15g02530 458 Bcin15g02540 568 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin15g02550 427 Alpha crystallin/Hsp20 domain + HSP20-like chaperone + Small heat shock protein HSP20 Bcin15g02560 137 Effector(V1) Bcin15g02570 713 LEM/LEM-like domain + Inner nuclear membrane protein MAN1 + HeH/LEM domain Bcin15g02580 507 SignalP-noTM Extracellular membrane protein, CFEM domain Bcin15g02590 2143 yes Signaling pathway Bac, Adenylate cyclase Bcin15g02600 456 "Bcpkp2, similar to yeast PKP2, Mitochondrial protein kinase; negatively regulates activity of the pyruvate dehydrogenase complex by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp1p and phosphatases Ptc5p and Ptc6p; relocalizes from mitochondrion to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000003027]" Bcin15g02610 386 "Bccdc12, similar to yeast CDC12, Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate with other rods to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells [Source:SGD;Acc:S000001149]" Bcin15g02620 892 WD40 repeat + Small-subunit processome, Utp12 + WD40/YVTN repeat-like-containing domain + WD40-repeat-containing domain + WD40 repeat, conserved site + G-protein beta WD-40 repeat + Periodic tryptophan protein 2 Bcin15g02630 506 DNA ligase, ATP-dependent, N-terminal Bcin15g02640 549 Domain of unknown function DUF4048 Bcin15g02650 417 "Bcnpy1, similar to yeast NPY1, NADH diphosphatase (pyrophosphatase); hydrolyzes the pyrophosphate linkage in NADH and related nucleotides; localizes to peroxisomes; nudix hydrolase family member [Source:SGD;Acc:S000003035]" Bcin15g02660 358 PQ-loop repeat Bcin15g02670 124 Bcin15g02680 195 Effector(V2)|Effector(V1) Bcin15g02690 176 Effector(V2)|Effector(V1) Phenolic acid decarboxylase, bacterial + Calycin-like + Calycin Bcin15g02700 845 "Bcssl2, similar to yeast SSL2, Component of RNA polymerase transcription factor TFIIH holoenzyme; has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; interacts functionally with TFIIB and has roles in transcription start site selection and in gene looping to juxtapose initiation and termination regions; involved in DNA repair; relocalizes to the cytosol in response to hypoxia; homolog of human ERCC3 [Source:SGD;Acc:S000001405]" Bcin15g02710 123 Effector(V2)|Effector(V1) Zinc finger, CHY-type Bcin15g02720 267 Protease//Effector(V2)|Effector(V1) "Bcpre6, similar to yeast PRE6, Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress [Source:SGD;Acc:S000005398]" Bcin15g02730 552 FAD-linked oxidase, C-terminal + FAD linked oxidase, N-terminal + FAD-linked oxidase-like, C-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 + Vanillyl-alcohol oxidase, C-terminal subdomain 2 Bcin15g02740 241 Glutathione S-transferase, N-terminal + Thioredoxin-like fold Bcin15g02750 658 Ankyrin repeat + Ankyrin repeat-containing domain Bcin15g02760 286 BTB/POZ-like + BTB/POZ fold Bcin15g02770 482 Bcin15g02780 480 Bcin15g02790 150 Effector(V1) Bcin15g02800 268 BTB/POZ-like + BTB/POZ fold Bcin15g02810 117 Effector(V1) Bcin15g02820 1465 CbxX/CfqX + AAA+ ATPase domain + ATPase, AAA-type, core + P-loop containing nucleoside triphosphate hydrolase Bcin15g02830 591 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin15g02840 435 BTB/POZ-like + BTB/POZ fold Bcin15g02850 260 BTB/POZ-like + BTB/POZ fold Bcin15g02860 214 Ribosomal protein L19 + Translation protein SH3-like domain Bcin15g02870 409 Bcin15g02880 377 Serine/threonine dehydratase, pyridoxal-phosphate-binding site + Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site + Tryptophan synthase beta subunit-like PLP-dependent enzyme Bcin15g02890 1092 "Bcycg1, similar to yeast YCG1, Subunit of the condensin complex; required for establishment and maintenance of chromosome condensation, chromosome segregation and chromatin binding of the condensin complex; required for clustering of tRNA genes at the nucleolus; required for replication slow zone (RSZ) breakage following Mec1p inactivation [Source:SGD;Acc:S000002733]" Bcin15g02900 183 Effector(V2)|Effector(V1) Thioesterase superfamily + HotDog domain Bcin15g02910 489 Effector(V1) Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin15g02920 229 Bcin15g02930 598 F-box domain + Leucine-rich repeat domain, L domain-like Bcin15g02940 324 Male sterility, NAD-binding + NAD(P)-binding domain Bcin15g02950 844 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin15g02960 437 "Bchat2, similar to yeast HAT2, Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing [Source:SGD;Acc:S000000782]" Bcin15g02970 1389 Putative 5-3 exonuclease + 5'-3' exoribonuclease 1 + 5'-3' exoribonuclease Bcin15g02980 1120 "Bcvps54, similar to yeast VPS54, Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; potentially phosphorylated by Cdc28p; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p [Source:SGD;Acc:S000002434]" Bcin15g02990 720 Mini-chromosome maintenance, DNA-dependent ATPase + DNA replication licensing factor Mcm + Nucleic acid-binding, OB-fold + Mini-chromosome maintenance, conserved site + P-loop containing nucleoside triphosphate hydrolase + MCM N-terminal domain + Mini-chromosome maintenance protein + MCM OB domain Bcin15g03000 670 SignalP-noTM Bcin15g03010 180 SignalP-noTM Bcin15g03020 1071 "Bcctk1, similar to yeast CTK1, Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]" Bcin15g03030 245 Effector(V2)|Effector(V1) MHCK/EF2 kinase + Protein kinase-like domain Bcin15g03040 287 SignalP-noTM Bcin15g03050 339 CAZy : GT32 Glycosyltransferase, DXD sugar-binding motif + Nucleotide-diphospho-sugar transferases Bcin15g03060 399 Vacuolar protein sorting-associated protein 62 + Aerolysin-like toxin, beta complex domain Bcin15g03070 451 CAZy : GH16FCW //SignalP-noTM Bccrh2, Chitin transglycosylase Bcin15g03080 202 yes CAZy : CE5PCW hemicellulose//SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Early secretome BccutA, Cutinase A Bcin15g03090 280 Effector(V1) Copper homeostasis protein CutC + Copper homeostasis CutC domain Bcin15g03100 519 Leucine-rich repeat domain, L domain-like Bcin15g03110 527 Bcin15g03120 347 "Bcerg20, similar to yeast ERG20, Farnesyl pyrophosphate synthetase; has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis [Source:SGD;Acc:S000003703]" Bcin15g03130 667 "Bccdc23, similar to yeast CDC23, Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition [Source:SGD;Acc:S000001209]" Bcin15g03140 323 CAZy : AA9 //SignalP-noTM Cellulose-binding domain, fungal + Glycoside hydrolase, family 61 Bcin15g03150 587 Protease//SignalP-noTM//Early secretome Peptidase S8/S53 domain + Proteinase inhibitor, propeptide + Peptidase S53, propeptide + Sedolisin domain Bcin15g03160 315 dTDP-4-dehydrorhamnose reductase family + NAD(P)-binding domain + RmlD-like substrate binding domain Bcin15g03170 416 O-methyltransferase, family 2 + Winged helix-turn-helix DNA-binding domain + O-methyltransferase COMT-type + S-adenosyl-L-methionine-dependent methyltransferase Bcin15g03180 210 Effector(V1) Bcin15g03190 794 Pleckstrin homology domain + Pleckstrin homology-like domain + Ubiquitin-related domain Bcin15g03200 568 AMP-dependent synthetase/ligase Bcin15g03210 281 Nuclear pore complex component Bcin15g03220 902 Hid-1 Bcin15g03230 533 Epoxide hydrolase, N-terminal + Alpha/Beta hydrolase fold Bcin15g03240 907 Cation transporter + Potassium/sodium transporter Trk/HKT + Potassium transporter Trk, fungi Bcin15g03250 156 SM 0//Effector(V2)|Effector(V1) Protein of unknown function DUF3328 Bcin15g03260 200 Effector(V2)|Effector(V1) GNAT domain + Acyl-CoA N-acyltransferase Bcin15g03270 109 SignalP-noTM Bcin15g03280 1696 F-box domain Bcin15g03290 834 "Bcabp1, similar to yeast ABP1, Actin-binding protein of the cortical actin cytoskeleton; important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization; inhibits barbed-end actin filament elongation; phosphorylation within its Proline-Rich Regio, mediated by Cdc28p and Pho85p, protects Abp1p from proteolysis mediated by its own PEST sequences; mammalian homologue of HIP-55 (hematopoietic progenitor kinase 1 [HPK1]-interacting protein of 55 kDa) [Source:SGD;Acc:S000000684]" Bcin15g03300 88 Effector(V2)|Effector(V1) Cysteine-rich transmembrane CYSTM domain Bcin15g03310 263 Bcgrx3, Glutaredoxin Bcin15g03320 438 SignalP-noTM//Early secretome Phosphoesterase Bcin15g03330 734 Bclcc6, Laccase Bcin15g03340 709 Fructose-2,6-bisphosphatase + Histidine phosphatase superfamily, clade-1 + 6-phosphofructo-2-kinase + P-loop containing nucleoside triphosphate hydrolase + Histidine phosphatase superfamily Bcin15g03350 389 "Bcrnh1, similar to yeast RNH1, Ribonuclease H1; able to bind double-stranded RNAs and RNA-DNA hybrids; associates with RNAse polymerase I. [Source:SGD;Acc:S000004847]" Bcin15g03360 579 Transporter Cation/H+ exchanger Bcin15g03370 422 Glyoxalase/fosfomycin resistance/dioxygenase domain + 4-hydroxyphenylpyruvate dioxygenase + Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Bcin15g03380 270 Bcin15g03390 575 yes Signaling pathway Bcvel1,BcveA, Velvet-like 1, component of the Velvet protein complex, protein implicated in photoreponses Bcin15g03400 786 Bcin15g03410 1465 Ankyrin repeat + IPT domain + Immunoglobulin-like fold + Immunoglobulin E-set + Ankyrin repeat-containing domain Bcin15g03420 741 yes CAZy : GT39 Bcpmt2, Protein o-mannosyltransferase, subfamily PMT2 Bcin15g03430 568 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin15g03440 299 Chitin synthase III catalytic subunit Bcin15g03450 478 Cys2His2 transcription factor Bcssl1, Cys2His2 transcription factor Bcin15g03460 286 WW domain Bcin15g03470 168 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1)//Early secretome "Bcnpc2, similar to yeast NPC2, Functional homolog of human NPC2/He1; human NPC2 is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes [Source:SGD;Acc:S000002204]" Bcin15g03480 124 Effector(V1) "Bcvma7, similar to yeast VMA7, Subunit F of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane; the V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase) has eight subunits [Source:SGD;Acc:S000003252]" Bcin15g03490 478 Protein of unknown function DUF2418 Bcin15g03500 639 Bcin15g03510 577 Bcin15g03520 522 "Bcarh1, similar to yeast ARH1, Oxidoreductase of the mitochondrial inner membrane; involved in cytoplasmic and mitochondrial iron homeostasis and required for activity of Fe-S cluster-containing enzymes; one of the few mitochondrial proteins essential for viability [Source:SGD;Acc:S000002784]" Bcin15g03530 349 "Bcaim45, similar to yeast AIM45, Putative ortholog of mammalian ETF-alpha; interacts with frataxin, Yfh1p; null mutant displays elevated frequency of mitochondrial genome loss; may have a role in oxidative stress response; ETF-alpha is an electron transfer flavoprotein complex subunit [Source:SGD;Acc:S000006208]" Bcin15g03540 701 SANT/Myb domain + SWIRM domain + Homeodomain-like + Winged helix-turn-helix DNA-binding domain + SANT domain + SMARCC, C-terminal Bcin15g03550 706 SANT/Myb domain + Homeodomain-like Bcin15g03560 668 "Bcirc3, similar to yeast IRC3, Putative RNA helicase of the DEAH/D-box family; null mutant displays increased levels of spontaneous Rad52p foci; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion [Source:SGD;Acc:S000002740]" Bcin15g03570 561 Bcin15g03580 354 yes Signaling pathway Bcsak1, Mitogen-activated protein kinase Bcin15g03590 759 "Bcavl9, similar to yeast AVL9, Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000004104]" Bcin15g03600 772 "Bccdc53, similar to yeast CDC53, Cullin; structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation [Source:SGD;Acc:S000002290]" Bcin15g03610 355 yes Signaling pathway Bcg3, G protein alpha 3 subunit Bcin15g03620 884 CAZy : GT35 "Bcgph1, similar to yeast GPH1, Glycogen phosphorylase required for the mobilization of glycogen; non-essential; regulated by cyclic AMP-mediated phosphorylation; expression is regulated by stress-response elements and by the HOG MAP kinase pathway [Source:SGD;Acc:S000006364]" Bcin15g03630 259 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin15g03640 472 FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin15g03650 477 SignalP-TM "Bctms1, similar to yeast TMS1, Vacuolar membrane protein of unknown function; is conserved in mammals; predicted to contain eleven transmembrane helices; interacts with Pdr5p, a protein involved in multidrug resistance [Source:SGD;Acc:S000002512]" Bcin15g03660 514 Major facilitator superfamily + Major facilitator superfamily domain Bcin15g03670 1164 "Bcbst1, similar to yeast BST1, GPI inositol deacylase of the endoplasmic reticulum (ER); negatively regulates COPII vesicle formation; prevents production of vesicles with defective subunits; required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules; functional ortholog of human PGAP1, mutation of which is associated with intellectual disability and encephalopathy [Source:SGD;Acc:S000001869]" Bcin15g03680 1010 "Bcmcd4, similar to yeast MCD4, Protein involved in GPI anchor synthesis; multimembrane-spanning protein that localizes to the endoplasmic reticulum; highly conserved among eukaryotes; GPI stands for glycosylphosphatidylinositol [Source:SGD;Acc:S000001648]" Bcin15g03690 929 Zn2/Cys6 + fungal trans transcription factor//Signaling pathway Bcctf1a, Zn2/Cys6 transcription factor, cutinase transcription factor 1 alpha Bcin15g03700 631 Bcin15g03710 813 Bcin15g03720 117 Effector(V2)|Effector(V1) GTP cyclohydrolase 1 type 2/Nif3 Bcin15g03730 260 Ribonuclease H domain + Ribonuclease H-like domain Bcin15g03740 916 P-loop containing nucleoside triphosphate hydrolase Bcin15g03750 426 Target SNARE coiled-coil domain Bcin15g03760 219 Bcin15g03770 663 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin15g03780 894 "Bcdhr2, similar to yeast DHR2, Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis [Source:SGD;Acc:S000001561]" Bcin15g03790 903 "Bcapc2, similar to yeast APC2, Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the catalytic core of the APC/C; has similarity to cullin Cdc53p [Source:SGD;Acc:S000004117]" Bcin15g03800 609 Myosin-binding domain Bcin15g03810 430 Bcin15g03820 269 Translation protein, beta-barrel domain + Threonyl/alanyl tRNA synthetase, SAD + Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain + Alanyl-tRNA synthetase, class IIc, N-terminal Bcin15g03830 65 Effector(V2)|Effector(V1) Bcin15g03840 247 Effector(V2)|Effector(V1) Bcin15g03850 114 ER membrane protein complex subunit 6 + Rab5-interacting protein family Bcin15g03860 514 Pyridine nucleotide-disulphide oxidoreductase, class-II + Flavin monooxygenase-like + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin15g03870 257 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Cellulose-binding domain, fungal Bcin15g03880 110 Bcin15g03890 513 Forkhead-associated (FHA) domain Bcin15g03900 393 "Bccic1, similar to yeast CIC1, Essential protein that interacts with proteasome components; has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles [Source:SGD;Acc:S000001094]" Bcin15g03910 364 SignalP-noTM Palmitoyl protein thioesterase + Alpha/Beta hydrolase fold + Palmitoyl-protein thioesterase 1 Bcin15g03920 441 Cyclin, N-terminal + Cyclin-like Bcin15g03930 280 "Bcpom33, similar to yeast POM33, Transmembrane nucleoporin; involved in nuclear pore complex (NPC) distribution, assembly or stabilization; highly conserved across species, orthologous to human TMEM33 and paralogous to Per33p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003946]" Bcin15g03940 744 Heterokaryon incompatibility Bcin15g03950 199 Effector(V2)|Effector(V1) 3-beta hydroxysteroid dehydrogenase/isomerase + NAD(P)-binding domain Bcin15g03960 342 Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin15g03970 222 Protein of unknown function DUF3328 Bcin15g03980 149 Effector(V2)|Effector(V1) NTF2-like domain Bcin15g03990 231 Protein of unknown function DUF3328 Bcin15g04000 235 Effector(V1) Protein of unknown function DUF3328 Bcin15g04010 118 SignalP-TM Bcin15g04020 335 Bcin15g04030 208 Effector(V2)|Effector(V1) FMN-binding split barrel Bcin15g04040 312 yes Signaling pathway Bcspt3, Saga-like transcriptional regulatory complex subunit spt3 Bcin15g04050 968 Bcin15g04060 1620 "Bcrkr1, similar to yeast RKR1, RING domain E3 ubiquitin ligase; involved in ubiquitin-mediated degradation of non-stop proteins; component of ribosome-bound RQC (ribosome quality control) complex required for degradation of polypeptides arising from stalled translation; degrades products of mRNAs lacking a termination codon regardless of a poly(A) tail; functional connections to chromatin modification; homolog of mouse Listerin, mutations in which reported to cause neurodegeneration [Source:SGD;Acc:S000004861]" Bcin15g04070 547 Bcin15g04080 176 Bcin15g04090 527 Bcin15g04100 97 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin15g04110 387 "Bccak1, similar to yeast CAK1, Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases [Source:SGD;Acc:S000001865]" Bcin15g04120 849 "Bcsyp1, similar to yeast SYP1, Negative regulator of WASP-Arp23 complex; involved in endocytic site formation; directly inhibits Las17p stimulation of Arp23 complex-mediated actin assembly in vitro; may regulate assembly and disassembly of the septin ring; colocalizes and interacts with septin subunits; potential role in actin cytoskeletal organization [Source:SGD;Acc:S000000626]" Bcin15g04130 333 Bcin15g04140 600 yes Protease Bcbir1, Chromosome segregation regulator, anti-apoptotic gene Bcin15g04150 496 Dihydroorotate dehydrogenase, class 2 + Dihydroorotate dehydrogenase domain + Aldolase-type TIM barrel Bcin15g04160 295 Bcin15g04170 276 Bcin15g04180 599 Protein kinase domain + Tyrosine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin15g04190 307 Tetratricopeptide TPR1 + U box domain + Tetratricopeptide-like helical domain + Tetratricopeptide repeat-containing domain + Zinc finger, RING/FYVE/PHD-type + Tetratricopeptide repeat Bcin15g04200 101 Effector(V2)|Effector(V1) Cytochrome b-c1 complex subunit 10, fungi Bcin15g04210 202 Bcin15g04220 598 "Bcdie2, similar to yeast DIE2, Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase; located in the ER; functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation; has a role in regulation of ITR1 and INO1 [Source:SGD;Acc:S000003459]" Bcin15g04230 232 Bcin15g04240 1002 Ankyrin repeat + Ankyrin repeat-containing domain + P-loop containing nucleoside triphosphate hydrolase Bcin15g04250 124 SignalP-noTM Bcin15g04260 344 Bcin15g04270 518 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin15g04280 233 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase Bcin15g04290 25 Effector(V2)|Effector(V1) Bcin15g04300 92 Effector(V2)|Effector(V1) Bcin15g04310 626 Heterokaryon incompatibility Bcin15g04320 582 AMP-dependent synthetase/ligase + AMP-binding, conserved site + AMP-binding enzyme C-terminal domain Bcin15g04330 526 Major facilitator superfamily + Major facilitator superfamily domain Bcin15g04340 235 "Bcpsf2, similar to yeast PSF2, Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p); complex is localized to DNA replication origins and implicated in assembly of the DNA replication machinery [Source:SGD;Acc:S000003608]" Bcin15g04350 512 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin15g04360 516 Bcin15g04370 268 HD domain Bcin15g04380 158 Bcin15g04390 847 Bcin15g04400 523 Bcin15g04410 705 Protease Peptidase M3A/M3B + Neurolysin/Thimet oligopeptidase, domain 2 + Metallopeptidase, catalytic domain + Neurolysin/Thimet oligopeptidase, N-terminal Bcin15g04420 139 "Bcmlc1, similar to yeast MLC1, Essential light chain for Myo1p; light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition [Source:SGD;Acc:S000003074]" Bcin15g04430 308 Methyltransferase type 11 + S-adenosyl-L-methionine-dependent methyltransferase Bcin15g04440 530 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin15g04450 160 Effector(V2)|Effector(V1) CoA-binding + NAD(P)-binding domain Bcin15g04460 606 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin15g04470 601 Prenylcysteine lyase + Prenylcysteine oxidase + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin15g04480 308 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin15g04490 576 Eukaryotic translation initiation factor 3 subunit D Bcin15g04500 597 Bcin15g04510 725 Zinc finger, C6HC-type + E3 ubiquitin ligase RBR family Bcin15g04520 903 SignalP-noTM Extracellular membrane protein, CFEM domain Bcin15g04530 196 Bcin15g04540 752 PAS domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core Bcin15g04550 370 SignalP-noTM Bcin15g04560 539 Protein of unknown function DUF4646 Bcin15g04570 479 BRO1 domain Bcin15g04580 146 Effector(V1) Bcin15g04590 207 Bromodomain transcription factor Bcin15g04600 532 "Bctaf7, similar to yeast TAF7, TFIID subunit (67 kDa); involved in RNA polymerase II transcription initiation [Source:SGD;Acc:S000004840]" Bcin15g04610 216 Effector(V1) Ribosomal protein L37, mitochondrial Bcin15g04620 102 Effector(V1) Complex I subunit NDUFS6 Bcin15g04630 492 "Bcnsr1, similar to yeast NSR1, Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis [Source:SGD;Acc:S000003391]" Bcin15g04640 1044 Bcin15g04650 247 Bcin15g04660 129 Protein of unknown function DUF4267 Bcin15g04670 615 Protease//SignalP-noTM//Early secretome Bcser8, Secreted protease Bcin15g04680 419 Bcin15g04690 735 Bcin15g04700 140 Bcin15g04710 540 Transporter Amino acid/polyamine transporter I Bcin15g04720 395 Bcin15g04730 242 S-adenosyl-L-methionine-dependent methyltransferase Bcin15g04740 109 Effector(V2)|Effector(V1) Bcin15g04750 530 SM cluster Rum1 Cytochrome P450 + Cytochrome P450, E-class, group II + Cytochrome P450, E-class, CYP52 + Cytochrome P450, conserved site Bcin15g04760 454 SM cluster Rum1 Transferase + Chloramphenicol acetyltransferase-like domain Bcin15g04770 178 SM cluster Rum1//SignalP-noTM//Effector(V1) Bcin15g04780 537 SM cluster Rum1 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin15g04790 301 SM cluster Rum1 ELO family Bcin15g04800 360 SM cluster Rum1 HotDog domain Bcin15g04810 832 Transporter//SM cluster Rum1 Major facilitator superfamily + Major facilitator superfamily domain Bcin15g04820 690 yes Zn2/Cys6 + fungal trans transcription factor//SM cluster Rum1//Signaling pathway Bcrum1, Zn2/Cys6 transcription factor, regulator of unknown metabolite 1, in a putative secondary metabolism cluster Bcin15g04830 577 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin15g04840 311 GPR1/FUN34/yaaH + Protein AlcS Bcin15g04850 134 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin15g04860 148 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin15g04870 185 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin15g04880 142 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin15g04890 192 Tannase/feruloyl esterase Bcin15g04900 292 Bcin15g04910 121 Effector(V2)|Effector(V1) Bcin15g04920 797 Bcin15g04930 106 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin15g04940 362 NmrA-like domain + NAD(P)-binding domain Bcin15g04950 169 Transmembrane protein 6/97 + EXPERA domain Bcin15g04960 339 SignalP-noTM Bcin15g04970 549 "Bcpgi1, similar to yeast PGI1, Glycolytic enzyme phosphoglucose isomerase; catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate; required for cell cycle progression and completion of the gluconeogenic events of sporulation [Source:SGD;Acc:S000000400]" Bcin15g04980 638 Protein kinase domain + AGC-kinase, C-terminal + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site + Protein kinase, C-terminal Bcin15g04990 516 "Bcada2, similar to yeast ADA2, Transcription coactivator; component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes [Source:SGD;Acc:S000002856]" Bcin15g05000 689 Zn2/Cys6 + fungal trans transcription factor//Effector(V1) Zn(2)-C6 fungal-type DNA-binding domain Bcin15g05010 290 Ribosomal protein S21 Bcin15g05020 768 RNA recognition motif domain + PWI domain + Nucleotide-binding alpha-beta plait domain Bcin15g05030 414 CAZy : GH28PCW pectin//SignalP-noTM Glycoside hydrolase, family 28 + Pectin lyase fold/virulence factor + Pectin lyase fold Bcin15g05040 1221 Effector(V2)|Effector(V1) Domain of unknown function DUF4470 + Zinc finger, MYND-type Bcin15g05050 388 Piwi domain + Ribonuclease H-like domain Bcin15g05060 674 PAZ domain + Domain of unknown function DUF1785 + Protein argonaute, N-terminal Bcin15g05070 851 HAUS augmin-like complex subunit 6, N-terminal Bcin15g05080 463 CAZy : GH72FCW //SignalP-noTM "Bcgas5, similar to yeast GAS5, 1,3-beta-glucanosyltransferase; has similarity to Gas1p; localizes to the cell wall [Source:SGD;Acc:S000005390]" Bcin15g05090 671 Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin15g05100 522 Effector(V1) "Bcfol1, similar to yeast FOL1, Multifunctional enzyme of the folic acid biosynthesis pathway; has dihydropteroate synthetase, dihydro-6-hydroxymethylpterin pyrophosphokinase, and dihydroneopterin aldolase activities [Source:SGD;Acc:S000005200]" Bcin15g05110 355 2-nitropropane dioxygenase, NPD + Aldolase-type TIM barrel Bcin15g05120 282 SignalP-TM Frag1/DRAM/Sfk1 Bcin15g05130 746 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Decarboxylase UbiX/Pad1 + Transcription factor domain, fungi Bcin15g05140 232 Effector(V2)|Effector(V1) Flavin reductase-like, FMN-binding + FMN-binding split barrel Bcin15g05150 513 UbiD decarboxylyase family + FMN-binding split barrel + UbiD-like decarboxylase/ferulic acid decarboxylase 1 Bcin15g05160 201 Effector(V2)|Effector(V1) Flavoprotein + Decarboxylase UbiX/Pad1 Bcin15g05170 945 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain Bcin15g05180 671 Protein of unknown function DUF3292 Bcin15g05190 326 SignalP-TM Actin cortical patch SUR7/pH-response regulator PalI Bcin15g05200 359 Bcin15g05210 476 Bcin15g05220 160 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin15g05230 227 Effector(V2) "Bctim21, similar to yeast TIM21, Nonessential component of the TIM23 complex; interacts with the Translocase of the Outer Mitochondrial membrane (TOM complex) and with respiratory enzymes; may regulate the Translocase of the Inner Mitochondrial membrane (TIM23 complex) activity [Source:SGD;Acc:S000003265]" Bcin15g05240 489 "Bcglo3, similar to yeast GLO3, ADP-ribosylation factor GTPase activating protein (ARF GAP); involved in ER-Golgi transport; shares functional similarity with Gcs1p [Source:SGD;Acc:S000000924]" Bcin15g05250 393 Effector(V2)|Effector(V1) AAA+ ATPase domain + DNA recombination and repair protein RecA + DNA recombination and repair protein RecA-like, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin15g05260 661 CAZy : GH76FCW //SignalP-noTM Glycoside hydrolase, family 76 + Six-hairpin glycosidase-like + Six-hairpin glycosidase Bcin15g05270 508 Bcpie2, Gene induced inEarly infection stage Bcin15g05280 167 SignalP-noTM Bcin15g05290 331 NADP-dependent oxidoreductase domain Bcin15g05300 615 p53-like transcription factor, DNA-binding + NDT80 DNA-binding domain Bcin15g05310 567 Leucine-rich repeat domain, L domain-like Bcin15g05320 417 SignalP-noTM Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin15g05330 592 "Bctam41, similar to yeast TAM41, Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase); required for cardiolipin biosynthesis; viability of null mutant is strain-dependent; mRNA is targeted to the bud; mutant displays defect in mitochondrial protein import, likely due to altered membrane lipid composition [Source:SGD;Acc:S000003278]" Bcin15g05340 767 "Bcmad1, similar to yeast MAD1, Coiled-coil protein involved in spindle-assembly checkpoint; required for inhibition of karyopherin/importin Pse1p (aka Kap121p) upon spindle assembly checkpoint arrest; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of anaphase promoting complex activity; forms a complex with Mad2p; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability [Source:SGD;Acc:S000003054]" Bcin15g05350 1851 SignalP-noTM Bcin15g05360 382 "Bcgal7, similar to yeast GAL7, Galactose-1-phosphate uridyl transferase; synthesizes glucose-1-phosphate and UDP-galactose from UDP-D-glucose and alpha-D-galactose-1-phosphate in the second step of galactose catabolism [Source:SGD;Acc:S000000222]" Bcin15g05370 816 SignalP-noTM Kelch-type beta propeller Bcin15g05380 273 Effector(V2) Crotonase superfamily + ClpP/crotonase-like domain Bcin15g05390 226 Effector(V2)|Effector(V1) Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Mss4-like Bcin15g05400 255 Protease ThiJ/PfpI + Class I glutamine amidotransferase-like Bcin15g05410 354 Bcin15g05420 325 BAR domain-containing family + Arfaptin homology (AH) domain/BAR domain Bcin15g05430 734 "Bcarg2, similar to yeast ARG2, Acetylglutamate synthase (glutamate N-acetyltransferase); mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine; forms a complex with Arg5,6p [Source:SGD;Acc:S000003607]" Bcin15g05440 305 6-phosphogluconate dehydrogenase, NADP-binding + 6-phosphogluconate dehydrogenase C-terminal domain-like + 6-phosphogluconate dehydrogenase, domain 2 + 3-hydroxyisobutyrate dehydrogenase-related + NAD(P)-binding domain + 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain Bcin15g05450 77 SignalP-TM "Bcvma9, similar to yeast VMA9, Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex; essential for vacuolar acidification; interacts with the V-ATPase assembly factor Vma21p in the ER; involved in V0 biogenesis [Source:SGD;Acc:S000028508]" Bcin15g05460 288 "Bcarv1, similar to yeast ARV1, Cortical ER protein; implicated in the membrane insertion of tail-anchored C-terminal single transmembrane domain proteins; may function in transport of glycosylphosphatidylinositol intermediates into ER lumen; required for normal intracellular sterol distribution; human ARV1 required for normal cholesterol and bile acid homeostasis; similar to Nup120p [Source:SGD;Acc:S000004232]" Bcin15g05470 428 Six-bladed beta-propeller, TolB-like Bcin15g05480 278 Bcin15g05490 441 CAZy : GT8 //SignalP-noTM Nucleotide-diphospho-sugar transferases Bcin15g05500 394 Bcin15g05510 535 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin15g05520 293 F-box domain Bcin15g05530 362 Bcin15g05540 156 "Bcerg28, similar to yeast ERG28, Endoplasmic reticulum membrane protein; may facilitate protein-protein interactions between the Erg26p dehydrogenase and the Erg27p 3-ketoreductase and/or tether these enzymes to the ER, also interacts with Erg6p [Source:SGD;Acc:S000000846]" Bcin15g05550 331 "Bcifa38, similar to yeast IFA38, Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides [Source:SGD;Acc:S000000363]" Bcin15g05560 1355 Nucleoporin, Nup155-like + Nucleoporin, Nup133/Nup155-like, C-terminal + Nucleoporin, Nup133/Nup155-like, N-terminal Bcin15g05570 393 Bcin15g05580 657 SignalP-noTM//Early secretome FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin15g05590 190 "Bcych1, similar to yeast YCH1, Phosphatase with sequence similarity to Cdc25p; Arr2p and Mih1p; member of the single-domain rhodanese homology superfamily; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus [Source:SGD;Acc:S000003435]" Bcin15g05600 389 yes CND9, CalciNeurine-Dependant (CND) gene, mannitol-1phosphatedeshydrogenase Bcin15g05610 858 Protease "Bcsec27, similar to yeast SEC27, Essential beta'-coat protein of the COPI coatomer; involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP [Source:SGD;Acc:S000003105]" Bcin15g05620 465 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin15g05630 330 3-beta hydroxysteroid dehydrogenase/isomerase + NAD(P)-binding domain Bcin15g05640 148 Effector(V2)|Effector(V1) Crotonase superfamily + ClpP/crotonase-like domain Bcin15g05650 248 Effector(V2) NAD-dependent epimerase/dehydratase, N-terminal domain + NAD(P)-binding domain Bcin15g05660 357 Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin15g05670 1054 Transporter//Effector(V2)|Effector(V1) Cation-transporting P-type ATPase, N-terminal + P-type ATPase + Cation-transporting P-type ATPase, C-terminal + P-type ATPase, subfamily IID + P-type ATPase, A domain + P-type ATPase, phosphorylation site + HAD-like domain + P-type ATPase, transmembrane domain + P-type ATPase, cytoplasmic domain N Bcin15g05680 579 Protease Carboxylesterase, type B + Carboxylesterase type B, conserved site + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin15g05690 282 Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin15g05700 606 Protease//SignalP-noTM Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin15g05710 449 Domain of unknown function DUF3533 Bcin15g05720 251 Protease Peptidase C12, ubiquitin carboxyl-terminal hydrolase Bcin16g00002 472 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin16g00003 223 Effector(V2)|Effector(V1) Bcin16g00004 97 Effector(V2)|Effector(V1) GroES (chaperonin 10)-like + Alcohol dehydrogenase GroES-like Bcin16g00005 830 UDP-glucuronosyl/UDP-glucosyltransferase + Glycosyltransferase family 28, N-terminal domain Bcin16g00006 611 SignalP-noTM FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin16g00010 362 SsuA/THI5-like Bcin16g00020 285 Bcin16g00030 424 Voltage-dependent anion channel + Malic acid transport protein Bcin16g00040 1098 Protease ArgE/DapE/ACY1/CPG2/YscS, conserved site + WD40 repeat + Peptidase M20 + Quinonprotein alcohol dehydrogenase-like superfamily + Peptidase M20, dimerisation domain + WD40/YVTN repeat-like-containing domain + Glutathione degradosome, DUG2 + WD40-repeat-containing domain Bcin16g00050 494 Protease Peptidase T2, asparaginase 2 + Nucleophile aminohydrolases, N-terminal Bcin16g00060 75 Effector(V1) Bcin16g00070 539 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin16g00080 580 SignalP-noTM FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin16g00090 233 Effector(V1) Small GTPase superfamily + Small GTPase superfamily, Ras type + P-loop containing nucleoside triphosphate hydrolase Bcin16g00100 90 Bcin16g00110 134 Effector(V2)|Effector(V1) Intradiol ring-cleavage dioxygenase, core Bcin16g00120 263 Bcprx3, Peroxiredoxin (AhpC/TSA family) Bcin16g00130 480 Heterokaryon incompatibility Bcin16g00140 328 Bcin16g00150 494 Bcin16g00160 503 "Bccox15, similar to yeast COX15, Protein required for the hydroxylation of heme O to form heme A; heme A is an essential prosthetic group for cytochrome c oxidase [Source:SGD;Acc:S000000943]" Bcin16g00170 131 SignalP-noTM//Effector(V2)|Effector(V1) Bcin16g00180 271 SM 0 Protein of unknown function DUF3328 Bcin16g00190 257 SM 0 Protein of unknown function DUF3328 Bcin16g00200 242 Bcin16g00210 263 NAD(P)-binding domain Bcin16g00220 346 Protein of unknown function DUF3425 Bcin16g00230 332 Effector(V2) NADP-dependent oxidoreductase domain Bcin16g00240 333 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin16g00250 344 NADP-dependent oxidoreductase domain Bcin16g00260 523 SignalP-noTM Bcin16g00270 168 LAMTOR1/MEH1 Bcin16g00280 111 Effector(V2)|Effector(V1) Bcin16g00290 266 F-box domain + RPEL repeat Bcin16g00300 264 Amidase signature domain Bcin16g00310 326 P-loop containing nucleoside triphosphate hydrolase Bcin16g00320 852 Zn2/Cys6 + fungal trans transcription factor//Signaling pathway Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin16g00330 285 Dienelactone hydrolase + Alpha/Beta hydrolase fold Bcin16g00340 300 Bcin16g00350 821 Zinc finger, PHD-type + Transcription elongation factor S-II, central domain + Zinc finger, FYVE/PHD-type + Spen paralogue and orthologue SPOC, C-terminal + Zinc finger, RING/FYVE/PHD-type + Zinc finger, PHD-type, conserved site + Zinc finger, PHD-finger Bcin16g00360 464 Heterokaryon incompatibility Bcin16g00370 758 Potassium transporter Kch Bcin16g00380 354 Bcin16g00390 396 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain Bcin16g00400 127 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) Bcin16g00410 561 Protease//SignalP-noTM Alpha/beta hydrolase fold-1 + Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal + Alpha/Beta hydrolase fold Bcin16g00420 359 Bcin16g00430 607 "Bckrs1, similar to yeast KRS1, Lysyl-tRNA synthetase [Source:SGD;Acc:S000002444]" Bcin16g00440 903 BRCT domain + ARID DNA-binding domain + Homeodomain-like + Rap1 Myb domain + TRF2-interacting telomeric protein/Rap1, C-terminal Bcin16g00450 413 Zinc finger, DHHC-type transcription factor "Bcswf1, similar to yeast SWF1, Palmitoyltransferase that acts on transmembrane proteins; including the SNAREs Snc1p, Syn8p, Tlg1p and likely all SNAREs; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; may have a role in vacuole fusion [Source:SGD;Acc:S000002533]" Bcin16g00460 823 Bcin16g00470 630 Amidase + Amidase, conserved site + Amidase signature domain Bcin16g00480 336 Alkylated DNA repair protein AlkB + Oxoglutarate/iron-dependent dioxygenase + Alpha-ketoglutarate-dependent dioxygenase AlkB-like Bcin16g00490 333 Bccdk1, Cyclin dependent kinase Bcin16g00500 191 "Bcfmn1, similar to yeast FMN1, Riboflavin kinase, produces riboflavin monophosphate (FMN); FMN is a necessary cofactor for many enzymes; predominantly localizes to the microsomal fraction and also found in the mitochondrial inner membrane [Source:SGD;Acc:S000002644]" Bcin16g00510 106 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V1) Bcin16g00520 693 Zn2/Cys6 transcription factor "Bcert1, similar to yeast ERT1, Transcriptional regulator; involved in regulation of gluconeogenesis and fermentable carbon utilization; GFP-fusion protein localizes to cytoplasm, nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays role in restricting Ty1 transposition; member of the zinc cluster family of proteins, similar to Rds2p [Source:SGD;Acc:S000000443]" Bcin16g00530 555 Transporter Sugar transporter, conserved site + Major facilitator superfamily + Major facilitator superfamily domain Bcin16g00540 64 Bcin16g00550 855 Bcin16g00560 639 Heterokaryon incompatibility Bcin16g00570 354 Sirtuin family + Sirtuin family, catalytic core domain + Sirtuin family, catalytic core small domain + DHS-like NAD/FAD-binding domain Bcin16g00580 346 CWC16 protein Bcin16g00590 291 Tudor domain Bcin16g00600 292 Effector(V2) P-loop containing nucleoside triphosphate hydrolase + Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 + Mrp, conserved site + Mrp/NBP35 ATP-binding protein Bcin16g00610 585 "Bcbfr2, similar to yeast BFR2, Component of the SSU and 90S preribosomes; involved in pre-18S rRNA processing; binds to U3 snoRNA and Mpp10p; multicopy suppressor of sensitivity to Brefeldin A; expression is induced during lag phase and also by cold shock [Source:SGD;Acc:S000002707]" Bcin16g00620 617 Bcin16g00630 611 yes Bcpck1, phosphoenolpyruvate carboxykinase Bcin16g00640 92 Ubiquitin-conjugating enzyme E2 + Ubiquitin-conjugating enzyme/RWD-like Bcin16g00650 356 "Bcecm31, similar to yeast ECM31, Ketopantoate hydroxymethyltransferase; required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate [Source:SGD;Acc:S000000380]" Bcin16g00660 122 Effector(V2)|Effector(V1) "Bcatg12, similar to yeast ATG12, Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p cojugate also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation [Source:SGD;Acc:S000000421]" Bcin16g00670 447 Aminoglycoside phosphotransferase + Tyrosine-protein kinase, active site + Protein kinase-like domain Bcin16g00680 94 Effector(V2)|Effector(V1) Bcin16g00690 512 Protease "Bcicp55, similar to yeast ICP55, Mitochondrial aminopeptidase; cleaves the N termini of at least 38 imported proteins after cleavage by the mitochondrial processing peptidase (MPP), thereby increasing their stability; member of the aminopeptidase P family [Source:SGD;Acc:S000000880]" Bcin16g00700 657 "Bcdbf4, similar to yeast DBF4, Regulatory subunit of Cdc7p-Dbf4p kinase complex; required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000002459]" Bcin16g00710 726 "Bcsup35, similar to yeast SUP35, Translation termination factor eRF3; has a role in mRNA deadenylation and decay; altered protein conformation creates the [PSI(+)] prion that modifies cellular fitness, alters translational fidelity by affecting reading frame selection, and results in a nonsense suppressor phenotype; many stress-response genes are repressed in the presence of [PSI(+)] [Source:SGD;Acc:S000002579]" Bcin16g00720 770 "Bcyrb30, similar to yeast YRB30, RanGTP-binding protein; inhibits RanGAP1 (Rna1p)-mediated GTP hydrolysis of RanGTP (Gsp1p); shares similarity to proteins in other fungi but not in higher eukaryotes [Source:SGD;Acc:S000003132]" Bcin16g00730 566 Protein kinase domain + AGC-kinase, C-terminal + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin16g00740 467 Transporter Molybdate-anion transporter MOT2 + Major facilitator superfamily domain + Ammonium/urea transporter Bcin16g00750 1169 Protease "Bcpan2, similar to yeast PAN2, Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex; complex acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes [Source:SGD;Acc:S000003062]" Bcin16g00760 39 Effector(V1) Aldehyde dehydrogenase domain + Aldehyde/histidinol dehydrogenase + Aldehyde dehydrogenase N-terminal domain Bcin16g00770 530 Effector(V1) Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin16g00780 309 Bcin16g00790 129 CAZy : GH71FCW //SignalP-noTM//Effector(V1) Glycoside hydrolase, family 71 Bcin16g00800 726 CAZy : GH71,CBM24,CBM24,CBM24FCW Glycoside hydrolase, family 71 Bcin16g00810 161 Bcin16g00820 805 yes Transporter Bcmdl1, Mitochondrial Inner Membrane ABC Transporter Bcin16g00830 496 "Bccdc37, similar to yeast CDC37, Essential Hsp90p co-chaperone; necessary for passage through the START phase of the cell cycle; stabilizes protein kinase nascent chains and participates along with Hsp90p in their folding [Source:SGD;Acc:S000002575]" Bcin16g00840 234 "Bcclc1, similar to yeast CLC1, Clathrin light chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; regulates endocytic progression; thought to regulate clathrin function; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion [Source:SGD;Acc:S000003399]" Bcin16g00850 411 CID domain + RNA polymerase II-binding domain + ENTH/VHS Bcin16g00860 226 Effector(V1) Bcin16g00870 71 Effector(V2) Bcin16g00880 822 Bcin16g00890 133 Effector(V2)|Effector(V1) Bcin16g00900 129 Effector(V2)|Effector(V1) Bcin16g00910 130 Effector(V2)|Effector(V1) Bcin16g00920 362 Bcin16g00930 417 SignalP-noTM//Early secretome CND3, CalciNeurine-Dependant (CND) gene Bcin16g00940 540 Transporter Amino acid/polyamine transporter I + Amino acid permease, conserved site + Amino acid permease/ SLC12A domain Bcin16g00950 1236 SignalP-noTM Chitin-binding, type 1 Bcin16g00960 612 Protease "Bccrn1, similar to yeast CRN1, Coronin; cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity; plays a role in regulation of actin patch assembly [Source:SGD;Acc:S000004421]" Bcin16g00970 194 Effector(V1) P-loop containing nucleoside triphosphate hydrolase Bcin16g00980 708 Heat shock protein 70 family Bcin16g00990 687 Bcin16g01000 778 CND8, CalciNeurine-Dependant (CND) gene Bcin16g01010 362 AdipoR/Haemolysin-III-related Bcin16g01020 93 Effector(V2) Bcin16g01030 101 Bcin16g01040 243 Acyl-CoA N-acyltransferase Bcin16g01050 414 SignalP-noTM PLC-like phosphodiesterase, TIM beta/alpha-barrel domain Bcin16g01060 126 Effector(V2)|Effector(V1) "Bcecm15, similar to yeast ECM15, Non-essential protein of unknown function; likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis [Source:SGD;Acc:S000000097]" Bcin16g01070 251 RNase P, subunit Pop3 Bcin16g01080 2542 Protease Peptidase C19, ubiquitin carboxyl-terminal hydrolase + Ubiquitin specific protease, conserved site + Protein of unknown function DUF3517 + Ubiquitin specific protease domain Bcin16g01090 194 SignalP-noTM Bcin16g01100 812 "Bcavo1, similar to yeast AVO1, Component of a membrane-bound complex containing the Tor2p kinase; contains Tor2p kinase and other proteins; may have a role in regulation of cell growth [Source:SGD;Acc:S000005438]" Bcin16g01110 397 Proline-rich protein PRCC Bcin16g01120 435 Bcin16g01130 487 yes Signaling pathway Bcpka1, PKA catalytic subunit Bcin16g01140 300 Bcin16g01150 359 Domain of unknown function DUF2040 Bcin16g01160 97 Effector(V2)|Effector(V1) "Bctim13, similar to yeast TIM13, Mitochondrial intermembrane space protein; forms a complex with Tim8p that delivers a subset of hydrophobic proteins to the TIM22 complex for insertion into the inner membrane [Source:SGD;Acc:S000003413]" Bcin16g01170 333 SignalP-noTM Legume-like lectin + Concanavalin A-like lectin/glucanase domain Bcin16g01180 487 "Bczrt3, similar to yeast ZRT3, Vacuolar membrane zinc transporter; transports zinc from storage in the vacuole to the cytoplasm when needed; transcription is induced under conditions of zinc deficiency [Source:SGD;Acc:S000001658]" Bcin16g01190 387 Bcin16g01200 343 "Bcnuc1, similar to yeast NUC1, Major mitochondrial nuclease; has RNAse and DNA endo- and exonucleolytic activities; roles in mitochondrial recombination, apoptosis and maintenance of polyploidy; involved in fragmentation of genomic DNA during PND (programmed nuclear destruction); encodes ortholog of mammalian endoG [Source:SGD;Acc:S000003744]" Bcin16g01210 616 "Bcpfs2, similar to yeast PFS2, Integral subunit of the pre-mRNA CPF complex; the cleavage and polyadenylation factor (CPF) complex plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex [Source:SGD;Acc:S000005261]" Bcin16g01220 528 Membrane bound O-acyl transferase, MBOAT + Sterol O-acyltransferase, ACAT/DAG/ARE types + Diacylglycerol O-acyltransferase 1 Bcin16g01230 323 "Bcste14, similar to yeast STE14, Farnesyl cysteine-carboxyl methyltransferase; mediates the carboxyl methylation step during C-terminal CAAX motif processing of a-factor and RAS proteins in the endoplasmic reticulum, localizes to the ER membrane [Source:SGD;Acc:S000002818]" Bcin16g01240 219 Effector(V2)|Effector(V1) Bacterial transferase hexapeptide repeat + Trimeric LpxA-like + Maltose/galactoside acetyltransferase Bcin16g01250 145 Transmembrane protein 170 Bcin16g01260 689 Bcin16g01270 343 Bcddr48, DNA-damage response protein Bcin16g01280 234 Pre-mRNA-splicing factor Cwf15/Cwc15 Bcin16g01290 294 "Bcrrp45, similar to yeast RRP45, Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp45p (PM/SCL-75, EXOSC9); protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002688]" Bcin16g01300 883 Chloride channel, voltage gated + Chloride channel, core Bcin16g01310 262 SGNH hydrolase-type esterase domain Bcin16g01320 631 Bcin16g01330 200 Effector(V2)|Effector(V1) Isochorismatase-like Bcin16g01340 522 "Bcthi6, similar to yeast THI6, Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern [Source:SGD;Acc:S000006135]" Bcin16g01350 427 "Bctif5, similar to yeast TIF5, Translation initiation factor eIF5; functions both as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP and as a GDP dissociation inhibitor to prevent recycling of eIF2 [Source:SGD;Acc:S000006245]" Bcin16g01360 1018 Effector(V2)|Effector(V1) "Bctti1, similar to yeast TTI1, Subunit of the ASTRA complex, involved in chromatin remodeling; telomere length regulator involved in the stability or biogenesis of PIKKs such as TORC1; similar to S. pombe Tti1p; detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000001516]" Bcin16g01370 438 Aspartate/glutamate/uridylate kinase + Glutamate/acetylglutamate kinase + PUA domain + Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase + PUA-like domain + Glutamate 5-kinase, conserved site Bcin16g01380 244 Protease "Bcatp23, similar to yeast ATP23, Putative metalloprotease of the mitochondrial inner membrane; required for processing of Atp6p; has an additional role in assembly of the F0 sector of the F1F0 ATP synthase complex; substrate of the Mia40p-Erv1p disulfide relay system, and folding is assisted by Mia40p [Source:SGD;Acc:S000005303]" Bcin16g01390 403 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site + Aurora kinase Bcin16g01400 276 "Bctip41, similar to yeast TIP41, Protein that interacts with Tap42p, which regulates PP2A; component of the TOR (target of rapamycin) signaling pathway; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006244]" Bcin16g01410 510 Cytochrome P450 + Cytochrome P450, E-class, group I Bcin16g01420 545 SET domain Bcin16g01430 587 Effector(V2)|Effector(V1) Permease, cytosine/purines, uracil, thiamine, allantoin Bcin16g01440 608 Major facilitator superfamily + Major facilitator superfamily domain Bcin16g01450 339 Protease Peptidase S54, rhomboid domain Bcin16g01460 397 SignalP-noTM Tyrosinase copper-binding domain + Uncharacterised domain, di-copper centre Bcin16g01470 289 Early secretome "Bcrny1, similar to yeast RNY1, Vacuolar RNase of the T(2) family; relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; promotes apoptosis under stress conditions and this function is independent of its catalytic activity [Source:SGD;Acc:S000006044]" Bcin16g01480 496 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin16g01490 531 Cytochrome P450 + Cytochrome P450, E-class, group IV + Cytochrome P450, conserved site Bcin16g01500 682 Bcin16g01510 437 Homeobox transcription factor Homeobox domain + Homeobox KN domain + Homeodomain-like Bcin16g01520 1003 "Bckar3, similar to yeast KAR3, Minus-end-directed microtubule motor; functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate [Source:SGD;Acc:S000006345]" Bcin16g01530 339 Bcin16g01540 488 Transcription factor Iwr1 Bcin16g01550 1117 Immunoglobulin E-set + AMP-activated protein kinase, glycogen-binding domain Bcin16g01560 607 CAZy : GT69 Mannosyltransferase 1, CMT1 Bcin16g01570 507 Transporter Major facilitator superfamily + Major facilitator superfamily domain Bcin16g01580 254 Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin16g01590 421 CAZy : GH18,CBM1FCW //SignalP-noTM Cellulose-binding domain, fungal + Glycoside hydrolase, family 18, catalytic domain + Glycoside hydrolase, chitinase active site + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily Bcin16g01600 210 Effector(V2)|Effector(V1) FAD linked oxidase, N-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 Bcin16g01610 329 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB Bcin16g01620 160 Bcin16g01630 424 SignalP-noTM//Effector(V1) Ricin B lectin domain Bcin16g01640 547 "Bccct8, similar to yeast CCT8, Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo [Source:SGD;Acc:S000003545]" Bcin16g01650 296 HMG (high mobility group) transcription factor High mobility group box domain Bcin16g01660 529 "Bcrmd1, similar to yeast RMD1, Cytoplasmic protein required for sporulation [Source:SGD;Acc:S000002159]" Bcin16g01670 1078 SignalP-noTM NB-ARC + Tetratricopeptide-like helical domain + Tetratricopeptide repeat + P-loop containing nucleoside triphosphate hydrolase + NACHT-NTPase and P-loop NTPases, N-terminal domain Bcin16g01680 167 NUDIX hydrolase domain + NUDIX hydrolase domain-like + NUDIX hydrolase, conserved site + NUDIX hydrolase Bcin16g01690 91 Effector(V1) Bcin16g01700 134 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa//Effector(V2)|Effector(V1) RlpA-like double-psi beta-barrel domain Bcin16g01710 239 Cys2His2 transcription factor//Effector(V2)|Effector(V1) Zinc finger, C2H2 + Zinc finger C2H2-type/integrase DNA-binding domain + Zinc finger, C2H2-like Bcin16g01720 1009 Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin16g01730 403 Protease Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin16g01740 328 SET domain Bcin16g01750 337 Protease//Effector(V2)|Effector(V1) Alpha/beta hydrolase fold-3 + Alpha/Beta hydrolase fold Bcin16g01760 326 Arylamine N-acetyltransferase Bcin16g01770 806 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin16g01780 1175 yes Signaling pathway BcFar1, Scaffold protein Bcin16g01790 1462 NACHT nucleoside triphosphatase + P-loop containing nucleoside triphosphate hydrolase Bcin16g01800 287 Protein of unknown function DUF3328 Bcin16g01810 283 SM 0 Protein of unknown function DUF3328 Bcin16g01820 255 yes SignalP-noTM Bccgf1, Conidial germination protein Bcin16g01830 1755 SM cluster PKS14 (KE) Bcpks14, Polyketide synthase Bcin16g01840 276 SM cluster PKS14//Effector(V2) Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin16g01850 123 Transporter//SM cluster PKS14 Major facilitator superfamily domain Bcin16g01860 592 Zn2/Cys6 transcription factor//SM cluster PKS14 Zn(2)-C6 fungal-type DNA-binding domain + Protein of unknown function DUF3468 Bcin16g01870 302 SM cluster PKS14//Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin16g01880 306 SM cluster PKS14 Winged helix-turn-helix DNA-binding domain + S-adenosyl-L-methionine-dependent methyltransferase + O-methyltransferase, family 2 + O-methyltransferase COMT-type Bcin16g01890 777 Zn2/Cys6 + fungal trans transcription factor//SM cluster PKS14 Zn(2)-C6 fungal-type DNA-binding domain Bcin16g01900 215 Bcin16g01910 510 Bcin16g01920 1472 TRAPP II complex, Trs120 Bcin16g01930 287 Zn2/Cys6 transcription factor//SM cluster DMATS1 Zn(2)-C6 fungal-type DNA-binding domain Bcin16g01940 442 SM cluster DMATS1 (KE)//Protease Bcdmats1, Dimethylallyl tryptophan synthase Bcin16g01950 829 CAZy : GH63 //SignalP-noTM "Bccwh41, similar to yeast CWH41, Processing alpha glucosidase I; ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress [Source:SGD;Acc:S000002995]" Bcin16g01960 295 Domain of unknown function DUF1777 Bcin16g01970 1085 "Bcgpi13, similar to yeast GPI13, ER membrane localized phosphoryltransferase; adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein [Source:SGD;Acc:S000003954]" Bcin16g01980 173 "Bcvps68, similar to yeast VPS68, Vacuolar membrane protein of unknown function; involved in vacuolar protein sorting; also detected in the mitochondria [Source:SGD;Acc:S000005489]" Bcin16g01990 537 "Bcsmi1, similar to yeast SMI1, Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity [Source:SGD;Acc:S000003461]" Bcin16g02000 156 Bcin16g02010 217 "Bcfes1, similar to yeast FES1, Hsp70 (Ssa1p) nucleotide exchange factor; required for the release of misfolded proteins from the Hsp70 system to the Ub-proteasome machinery for destruction; cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000305]" Bcin16g02020 375 yes Early secretome BcactA, Actin Bcin16g02030 300 Bcin16g02040 1111 "Bcsec8, similar to yeast SEC8, Essential 121 kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion; involved in ER and Golgi inheritance in small buds; relocalizes away from bud neck upon DNA replication stress [Source:SGD;Acc:S000006259]" Bcin16g02050 353 Elongator complex protein 5 Bcin16g02060 347 Effector(V2) Bcin16g02070 132 Bcin16g02080 111 Effector(V2)|Effector(V1) Bcin16g02090 529 yes Cys2His2 transcription factor//Signaling pathway Bcltf2, Light-responsive Cys2His2 transcription factor Bcin16g02100 106 "Bcurm1, similar to yeast URM1, Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs; receives sulfur from the E1-like enzyme Uba4p and transfers it to tRNA; also functions as a protein tag with roles in nutrient sensing and oxidative stress response [Source:SGD;Acc:S000001270]" Bcin16g02110 824 "Bcelp2, similar to yeast ELP2, Subunit of Elongator complex; Elongator is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin [Source:SGD;Acc:S000003432]" Bcin16g02120 282 "Bccaf16, similar to yeast CAF16, Part of evolutionarily-conserved CCR4-NOT regulatory complex; contains single ABC-type ATPase domain but no transmembrane domain; interacts with several subunits of Mediator [Source:SGD;Acc:S000001866]" Bcin16g02130 614 Protease//SignalP-noTM//Early secretome Carboxylesterase, type B + Carboxylesterase type B, active site + Alpha/Beta hydrolase fold Bcin16g02140 439 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain Bcin16g02150 196 Bcin16g02160 263 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin16g02170 449 Cleft lip and palate transmembrane 1 Bcin16g02180 393 Wax synthase domain Bcin16g02190 882 Protease ADC synthase + Anthranilate synthase component I, N-terminal + Para-aminobenzoate synthase + Chorismate-utilising enzyme, C-terminal + Glutamine amidotransferase + Class I glutamine amidotransferase-like Bcin16g02200 128 "Bcvps55, similar to yeast VPS55, Late endosomal protein involved in late endosome to vacuole transport; functional homolog of human obesity receptor gene-related protein (OB-RGRP) [Source:SGD;Acc:S000003805]" Bcin16g02210 266 Protease "Bcpre5, similar to yeast PRE5, Alpha 6 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004931]" Bcin16g02220 269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG + LOG family Bcin16g02230 215 Effector(V2) "Bcsec22, similar to yeast SEC22, R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog [Source:SGD;Acc:S000004258]" Bcin16g02240 316 Bcin16g02250 128 Effector(V1) Protein of unknown function DUF4267 Bcin16g02260 279 Effector(V2)|Effector(V1) Crotonase superfamily + ClpP/crotonase-like domain Bcin16g02270 474 Zinc finger, MYND-type + Plasmid pRiA4b, Orf3 + Protein MM3350-like domain Bcin16g02280 350 RNA recognition motif domain + Nucleotide-binding alpha-beta plait domain Bcin16g02290 1403 Bcin16g02300 736 Pentatricopeptide repeat Bcin16g02310 1456 "Bcpol1, similar to yeast POL1, Catalytic subunit of the DNA polymerase I alpha-primase complex; required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis [Source:SGD;Acc:S000005046]" Bcin16g02320 223 Effector(V1) Mso1, N-terminal domain Bcin16g02330 325 "Bcmak16, similar to yeast MAK16, Essential nuclear protein; constituent of 66S pre-ribosomal particles; required for maturation of 25S and 5.8S rRNAs; required for maintenance of M1 satellite double-stranded RNA of the L-A virus [Source:SGD;Acc:S000000023]" Bcin16g02340 144 Protein of unknown function DUF952 Bcin16g02350 480 Bcin16g02360 1555 "Bcbud4, similar to yeast BUD4, Anillin-like protein involved in bud-site selection; required for the axial budding pattern; localizes with septins to the bud neck in mitosis and may constitute an axial landmark for the next round of budding; required for the formation and disassembly of the double septin ring structure, and generally for septin organization; in vivo substrate of Cdc28p/Clb2p [Source:SGD;Acc:S000003852]" Bcin16g02370 110 Effector(V2)|Effector(V1) Bcin16g02380 464 SignalP-noTM Bcin16g02390 1005 Armadillo-type fold + Retinoic acid induced 16-like protein Bcin16g02400 90 Bcin16g02410 430 "Bccem1, similar to yeast CEM1, Mitochondrial beta-keto-acyl synthase; possible role in fatty acid synthesis; required for mitochondrial respiration [Source:SGD;Acc:S000000863]" Bcin16g02420 209 Bcin16g02430 499 CAZy : GHnc //SignalP-noTM Bcin16g02440 582 Amino acid transporter, transmembrane domain Bcin16g02450 512 P-loop containing nucleoside triphosphate hydrolase Bcin16g02460 802 Protease//SignalP-noTM Aspartic peptidase domain + Peptidase family A1 domain + Aspartic peptidase Bcin16g02470 739 SignalP-noTM Bcin16g02480 487 Bcin16g02490 409 SignalP-noTM//Early secretome Alpha/Beta hydrolase fold Bcin16g02500 166 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein + Membrane associated eicosanoid/glutathione metabolism-like domain Bcin16g02510 335 Effector(V2) Bcin16g02520 3100 Protein of unknown function DUF3638 + Protein of unknown function DUF3645 Bcin16g02530 118 Effector(V2)|Effector(V1) Protein kinase-like domain Bcin16g02540 271 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin16g02550 547 Zinc finger, CCHC-type + DDE superfamily endonuclease, CENP-B-like + HTH CenpB-type DNA-binding domain + DNA binding HTH domain, Psq-type + Homeodomain-like Bcin16g02560 742 SignalP-noTM//Early secretome Six-hairpin glycosidase-like + Domain of unknown function DUF1793 + Domain of unknown function DUF4965 + Domain of unknown function DUF5127 Bcin16g02570 284 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin16g02580 114 Effector(V1) Ubiquitin-like + Rad60/SUMO-like domain + Ubiquitin-related domain Bcin16g02590 235 Bcin16g02600 105 Effector(V2)|Effector(V1) Bcin16g02610 497 F-box domain + Leucine-rich repeat domain, L domain-like Bcin16g02620 444 Leucine-rich repeat domain, L domain-like Bcin16g02630 317 Protease Pyridoxal 5'-phosphate synthase subunit PdxT/SNO + PdxT/SNO family, conserved site + Class I glutamine amidotransferase-like Bcin16g02640 306 "Bcslc1, similar to yeast SLC1, 1-acyl-sn-glycerol-3-phosphate acyltransferase; catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; enzymatic activity detected in lipid particles and microsomes [Source:SGD;Acc:S000002210]" Bcin16g02650 41 Bcin16g02660 280 Bcin16g02670 651 Bcin16g02680 1039 Protease Peptidase M16, C-terminal domain + Peptidase M16 domain + Metalloenzyme, LuxS/M16 peptidase-like + Peptidase M16, N-terminal + Peptidase M16, middle/third domain Bcin16g02690 273 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 Bcin16g02700 601 Dihydroxy-acid/6-phosphogluconate dehydratase + Dihydroxy-acid dehydratase + Aconitase/3-isopropylmalate dehydratase, swivel + Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site Bcin16g02710 1033 Protease Cysteine peptidase, cysteine active site + Peptidase C2, calpain, catalytic domain Bcin16g02720 279 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin16g02730 576 Fungal lipase-like domain + Alpha/Beta hydrolase fold Bcin16g02740 153 Bcin16g02750 605 Bcin16g02760 255 Effector(V2) Bcin16g02770 353 Protease//SignalP-noTM//Early secretome Bcmp1, Similar to metalloproteinase (secreted protein) Bcin16g02780 346 BTB/POZ fold Bcin16g02790 563 Protease//SignalP-noTM//Early secretome Peptidase S28 + Alpha/Beta hydrolase fold Bcin16g02800 585 Heterokaryon incompatibility Bcin16g02810 192 Effector(V2) Calycin Bcin16g02820 609 "Bcilv3, similar to yeast ILV3, Dihydroxyacid dehydratase; catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids [Source:SGD;Acc:S000003777]" Bcin16g02830 285 Bcin16g02840 391 Effector(V1) Bcin16g02850 647 SignalP-noTM FAD linked oxidase, N-terminal + Berberine/berberine-like + FAD-binding, type 2 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin16g02860 270 "Bccab5, similar to yeast CAB5, Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC); subunits of this complex are: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p; probable dephospho-CoA kinase (DPCK) that catalyzes the last step in coenzyme A biosynthesis; null mutant lethality is complemented by E. coli coaE (encoding DPCK); detected in purified mitochondria in high-throughput studies; also localized to lipid droplets [Source:SGD;Acc:S000002604]" Bcin16g02870 947 Bcin16g02880 185 Effector(V2)|Effector(V1) Bcin16g02890 379 Oxoglutarate/iron-dependent dioxygenase + Non-haem dioxygenase N-terminal domain + Isopenicillin N synthase-like Bcin16g02900 567 Permease, cytosine/purines, uracil, thiamine, allantoin + Nucleobase cation symporter-1, NCS1 Bcin16g02910 324 "Bcmed6, similar to yeast MED6, Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001100]" Bcin16g02920 1308 "Bcecm16, similar to yeast ECM16, Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP; predominantly nucleolar in distribution; required for 18S rRNA synthesis [Source:SGD;Acc:S000004735]" Bcin16g02930 116 Effector(V2)|Effector(V1) Bcin16g02940 237 Protein of unknown function DUF3328 Bcin16g02950 300 Protein of unknown function DUF3328 Bcin16g02960 187 SignalP-noTM Bcin16g02970 1459 Transporter ABC transporter-like + AAA+ ATPase domain + ABC transporter type 1, transmembrane domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase + Alpha-factor-transporting ATPase Ste6 Bcin16g02980 528 Major facilitator superfamily + Major facilitator superfamily domain Bcin16g02990 456 GDP-fucose protein O-fucosyltransferase Bcin16g03000 434 SignalP-noTM Six-bladed beta-propeller, TolB-like + Major royal jelly protein/Protein yellow Bcin16g03010 2035 AAA+ ATPase domain + Tetratricopeptide-like helical domain + P-loop containing nucleoside triphosphate hydrolase Bcin16g03020 379 CAZy : GH5PCW/FCW //SignalP-noTM Glycoside hydrolase, family 5 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Glycoside hydrolase, family 5, conserved site Bcin16g03030 149 Bcin16g03040 520 Protein of unknown function DUF2985 Bcin16g03050 181 SignalP-noTM Bcin16g03060 661 Neurochondrin + Armadillo-type fold Bcin16g03070 882 CBS domain + Chloride channel, voltage gated + Chloride channel, core Bcin16g03080 615 yes BcVWF, von Willebrand type A domain containing protein Bcin16g03090 331 "Bcget4, similar to yeast GET4, Protein involved in inserting tail-anchored proteins into ER membranes; forms a complex with Mdy2p; highly conserved across species and homologous to human gene C7orf20 [Source:SGD;Acc:S000005690]" Bcin16g03100 225 Effector(V1) Bcin16g03110 419 Effector(V2)|Effector(V1) "Bcrai1, similar to yeast RAI1, Nuclear protein with decapping endonuclease activity; targets mRNAs with unmethylated 7-methylguanosine cap structures and 5'-triphosphates; binds to and stabilizes the exoribonuclease Rat1p; required for pre-rRNA processing; relocalizes to the cytosol in response to hypoxia; homologous to human DOM3Z [Source:SGD;Acc:S000003215]" Bcin16g03120 650 Malic oxidoreductase + Malic enzyme, N-terminal domain + Malic enzyme, NAD-binding + Malic enzyme, conserved site + NAD(P)-binding domain Bcin16g03130 371 "Bcrbg2, similar to yeast RBG2, Protein with a role in translation; forms a complex with Gir2p; has similarity to mammalian developmentally regulated GTP-binding protein [Source:SGD;Acc:S000003405]" Bcin16g03140 481 "Bccbf5, similar to yeast CBF5, Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs; acts on large and small rRNAs, on snRNA U2, and on some mRNAs; mutations in human ortholog dyskerin cause the disorder dyskeratosis congenita; small nucleolar ribonucleoprotein particles are also known as snoRNPs [Source:SGD;Acc:S000004165]" Bcin16g03150 1394 "Bcsac3, similar to yeast SAC3, mRNA export factor; required for biogenesis of the small ribosomal subunit; component of TREX-2 complex (Sac3p-Thp1p-Sus1p-Cdc31p) involved in transcription elongation and mRNA export from the nucleus; involved in post-transcriptional tethering of active genes to the nuclear periphery and to non-nascent mRNP; similar to the human germinal center-associated nuclear protein (GANP) [Source:SGD;Acc:S000002566]" Bcin16g03160 419 "Bcltv1, similar to yeast LTV1, Component of the GSE complex; GSE is required for proper sorting of amino acid permease Gap1p; required for ribosomal small subunit export from nucleus; required for growth at low temperature [Source:SGD;Acc:S000001626]" Bcin16g03170 662 "Bclsg1, similar to yeast LSG1, Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm [Source:SGD;Acc:S000003067]" Bcin16g03180 452 Acyl-CoA oxidase/dehydrogenase, central domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain + Acyl-CoA dehydrogenase/oxidase, N-terminal Bcin16g03190 128 Effector(V2)|Effector(V1) Spo12 Bcin16g03200 701 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Decarboxylase UbiX/Pad1 + Transcription factor domain, fungi Bcin16g03210 385 Bcin16g03220 124 Effector(V2)|Effector(V1) Bcin16g03230 796 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin16g03240 455 SignalP-noTM Cupin 1 + RmlC-like cupin domain + RmlC-like jelly roll fold + Bicupin, oxalate decarboxylase/oxidase Bcin16g03250 221 Bcin16g03260 647 Bcin16g03270 921 Bcin16g03280 1350 Transporter "Bcdrs2, similar to yeast DRS2, Trans-golgi network aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation and endocytosis; subject to auto-inhibition by its C-terminal tail; mutations in human homolog ATP8B1 result in liver disease [Source:SGD;Acc:S000000024]" Bcin16g03290 123 Effector(V2)|Effector(V1) PDZ-binding protein, CRIPT Bcin16g03300 316 Effector(V2) "Bccbp3, similar to yeast CBP3, Mitochondrial protein required for assembly of cytochrome bc1 complex; forms a complex with Cbp6p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with newly synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex; Cbp3p-Cbp6p complex is sequestered if assembly of Complex III is blocked, downregulating COB mRNA translation [Source:SGD;Acc:S000006136]" Bcin16g03310 226 Bcin16g03320 82 Effector(V1) Bcin16g03330 134 Effector(V1) Bcin16g03340 225 Effector(V2) "Bcdfr1, similar to yeast DFR1, Dihydrofolate reductase involved in tetrahydrofolate biosynthesis; required for respiratory metabolism [Source:SGD;Acc:S000005762]" Bcin16g03350 410 BTB/POZ-like + BTB/POZ fold Bcin16g03360 382 Protein of unknown function DUF1295 Bcin16g03370 404 Effector(V1) Transition metal uptake transporter nickel/cobalt + Nickel/cobalt transporter, high-affinity Bcin16g03380 266 yes Effector(V2)|Effector(V1) Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin16g03390 592 ATP-dependent RNA helicase DEAD-box, conserved site + Helicase, C-terminal + DEAD/DEAH box helicase domain + Helicase superfamily 1/2, ATP-binding domain + P-loop containing nucleoside triphosphate hydrolase Bcin16g03400 585 Mediator complex, subunit Med22 Bcin16g03410 330 "Bctwf1, similar to yeast TWF1, Twinfilin; highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton; coordinates actin filament severing and monomer sequestering at sites of rapid actin turnover; composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly [Source:SGD;Acc:S000003312]" Bcin16g03420 325 Transporter Mitochondrial carrier protein + Mitochondrial substrate/solute carrier + Mitochondrial carrier domain Bcin16g03430 562 Transporter Major facilitator superfamily domain Bcin16g03440 332 Life-span regulatory factor Bcin16g03450 324 Protease Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin16g03460 272 Oxoglutarate/iron-dependent dioxygenase + Prolyl 4-hydroxylase, alpha subunit Bcin16g03470 312 Bcin16g03480 631 "Bcpus1, similar to yeast PUS1, tRNA:pseudouridine synthase; introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; also acts on U2 snRNA; also pseudouridylates some mRNAs, and pseudouridylation level varies with growth phase; nuclear protein that appears to be involved in tRNA export; PUS1 has a paralog, PUS2, that arose from the whole genome duplication [Source:SGD;Acc:S000006133]" Bcin16g03490 449 "Bctfa1, similar to yeast TFA1, TFIIE large subunit; involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening [Source:SGD;Acc:S000001511]" Bcin16g03500 535 "Bccys4, similar to yeast CYS4, Cystathionine beta-synthase; catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; advances passage through START by promoting cell growth which requires catalytic activity, and reducing critical cell size independent of catalytic activity; mutations in human ortholog cause homocystinuria [Source:SGD;Acc:S000003387]" Bcin16g03510 262 SignalP-noTM Yeast cell wall synthesis Kre9/Knh1, C-terminal + Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Bcin16g03520 331 Cyclin PHO80-like Bcin16g03530 543 Protease Peptidase M24, structural domain + Aminopeptidase P, N-terminal + Creatinase/Aminopeptidase P, N-terminal + Creatinase/Aminopeptidase P/Spt16, N-terminal Bcin16g03540 586 SM cluster NRPS3 Thiamine pyrophosphate enzyme, C-terminal TPP-binding + Thiamine pyrophosphate enzyme, central domain + Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain + DHS-like NAD/FAD-binding domain + Thiamin diphosphate-binding fold Bcin16g03550 357 SM cluster NRPS3 Bcin16g03560 1330 Transporter//SM cluster NRPS3 ABC transporter type 1, transmembrane domain + ABC transporter-like + AAA+ ATPase domain + ABC transporter, conserved site + P-loop containing nucleoside triphosphate hydrolase Bcin16g03570 4695 SM cluster NRPS3 (KE) Bcnrps3, Nonribosomal peptide synthetase Bcin16g03580 533 Bcin16g03590 517 Bcin16g03600 529 CidB/LrgB family Bcin16g03610 149 Bcgst26, Microsomal glutathione S-transferase II (MAPEG family) Bcin16g03620 410 Protease Epoxide hydrolase-like + Epoxide hydrolase, N-terminal + Epoxide hydrolase + Alpha/Beta hydrolase fold Bcin16g03630 596 Protease//SignalP-noTM "Bcecm14, similar to yeast ECM14, Putative metalloprotease with similarity to zinc carboxypeptidases; required for normal cell wall assembly [Source:SGD;Acc:S000001174]" Bcin16g03640 110 Bcin16g03650 1434 Effector(V1) "Bcsyt1, similar to yeast SYT1, Guanine nucleotide exchange factor (GEF) for Arf proteins; promotes activation of Arl1p, which recruits Imh1p to the Golgi; involved in vesicular transport; member of the Sec7-domain family; contains a PH domain [Source:SGD;Acc:S000006299]" Bcin16g03660 651 "Bcsrp72, similar to yeast SRP72, Core component of the signal recognition particle (SRP); the SRP is a ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane [Source:SGD;Acc:S000006131]" Bcin16g03670 736 Zinc finger, DHHC-type transcription factor Zinc finger, DHHC-type, palmitoyltransferase + Ankyrin repeat + Ankyrin repeat-containing domain Bcin16g03680 289 "Bcsrp102, similar to yeast SRP102, Signal recognition particle (SRP) receptor beta subunit; involved in SRP-dependent protein targeting; anchors the alpha subunit, Srp101p to the ER membrane [Source:SGD;Acc:S000001637]" Bcin16g03690 683 BRCT domain + DNA polymerase family X, beta-like + DNA-directed DNA polymerase X + DNA polymerase beta-like, N-terminal domain + DNA polymerase lambda, fingers domain + DNA polymerase family X + DNA polymerase family X lyase domain + DNA polymerase beta, palm domain + DNA polymerase beta, thumb domain Bcin16g03700 179 Effector(V1) "Bcess1, similar to yeast ESS1, Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated serine and threonine residues N-terminal to proline; regulates phosphorylation of the RNAP II large subunit (Rpo21p) C-terminal domain (CTD); associates with phospho-Ser5 form of RNAP II in vivo; regulates phosphorylation of Ser7 within CTD; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription and trimethylation of histone H3 [Source:SGD;Acc:S000003778]" Bcin16g03710 128 Effector(V2)|Effector(V1) "Bcrpb9, similar to yeast RPB9, RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site selection and fidelity of transcription [Source:SGD;Acc:S000003038]" Bcin16g03720 134 Effector(V2)|Effector(V1) "Bcmrpl38, similar to yeast MRPL38, Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL34 and YmL38) on two-dimensional SDS gels; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001653]" Bcin16g03730 807 SET domain + Histone-lysine N-methyltransferase SET9 Bcin16g03740 411 Inositol phosphorylceramide synthase catalytic subunit Aur1 Bcin16g03750 304 BTB/POZ fold Bcin16g03760 414 Bcin16g03770 299 M-phase phosphoprotein 6 Bcin16g03780 187 Effector(V2)|Effector(V1) Zinc finger, CHCC-type Bcin16g03790 271 Cleavage/polyadenylation specificity factor subunit 5 Bcin16g03800 222 Effector(V2) Uncharacterised protein family UPF0047 Bcin16g03810 257 Cell fusion protein Dni1/Fig1 Bcin16g03820 448 Bcin16g03830 283 Effector(V2) Glucose/ribitol dehydrogenase + NAD(P)-binding domain + Short-chain dehydrogenase/reductase, conserved site Bcin16g03840 443 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin16g03850 297 Aminoglycoside phosphotransferase + Protein kinase-like domain Bcin16g03860 145 Effector(V2)|Effector(V1) Bcin16g03870 355 GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin16g03880 411 "Bccdc123, similar to yeast CDC123, Protein involved in nutritional control of the cell cycle; regulates abundance of the translation initiation factor eIF2; ortholog of human D123 protein [Source:SGD;Acc:S000004205]" Bcin16g03890 168 mRNA splicing factor, Cwf21 Bcin16g03900 271 Effector(V2)|Effector(V1) ClpP/crotonase-like domain + Crotonase superfamily Bcin16g03910 85 "Bcpet100, similar to yeast PET100, Chaperone that facilitates the assembly of cytochrome c oxidase; integral to the mitochondrial inner membrane; interacts with a subcomplex of subunits VII, VIIa, and VIII (Cox7p, Cox9p, and Cox8p) but not with the holoenzyme [Source:SGD;Acc:S000002486]" Bcin16g03920 290 Effector(V2)|Effector(V1) Transcriptional regulator TACO1-like + Integrase, N-terminal zinc-binding domain-like + Transcriptional regulator TACO1-like, domain 2 + Transcriptional regulator TACO1-like, domain 3 + YebC-like Bcin16g03930 2053 "Bclaa1, similar to yeast LAA1, AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene [Source:SGD;Acc:S000003743]" Bcin16g03940 570 Major facilitator superfamily domain + Autophagy-related protein 22-like Bcin16g03950 450 CAZy : GH7PCW cellulose//SignalP-noTM//Early secretome Glycoside hydrolase, family 7 + Concanavalin A-like lectin/glucanase domain Bcin16g03960 434 F-box domain + Leucine-rich repeat domain, L domain-like Bcin16g03970 700 Zn2/Cys6 + fungal trans transcription factor Zn(2)-C6 fungal-type DNA-binding domain + Transcription factor domain, fungi Bcin16g03980 576 CAZy : GH1PCW/FCW //SignalP-noTM Glycoside hydrolase, family 1 + Glycoside hydrolase, catalytic domain + Glycoside hydrolase superfamily + Glycosyl hydrolases family 1, N-terminal conserved site Bcin16g03990 315 SignalP-noTM Ferritin-like superfamily + Ferritin-related Bcin16g04000 1398 "Bcssd1, similar to yeast SSD1, Translational repressor with a role in polar growth and wall integrity; regulated by Cbk1p phosphorylation to effect bud-specific translational control and localization of specific mRNAs; interacts with TOR pathway components; contains a functional N-terminal nuclear localization sequence and nucleocytoplasmic shuttling appears to be critical to Ssd1p function [Source:SGD;Acc:S000002701]" Bcin16g04010 573 GLE1-like Bcin16g04020 312 SignalP-noTM Bcin16g04030 118 Effector(V2)|Effector(V1) Bcin16g04040 283 Aldo/keto reductase, conserved site + Aldo/keto reductase subgroup + NADP-dependent oxidoreductase domain Bcin16g04050 450 Glutamate/phenylalanine/leucine/valine dehydrogenase + Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal + Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain + Glutamate dehydrogenase + NAD(P)-binding domain + Leu/Phe/Val dehydrogenases active site Bcin16g04060 315 CAZy : GH16FCW //SignalP-noTM//Effector(V2)|Effector(V1) Glycoside hydrolase, family 16 + Concanavalin A-like lectin/glucanase domain Bcin16g04070 359 3-beta hydroxysteroid dehydrogenase/isomerase + NAD(P)-binding domain Bcin16g04080 653 Zn2/Cys6 transcription factor Zn(2)-C6 fungal-type DNA-binding domain Bcin16g04090 477 SignalP-noTM DOMON domain + Cellobiose dehydrogenase, cytochrome domain Bcin16g04100 76 Bcin16g04110 342 "Bcura1, similar to yeast URA1, Dihydroorotate dehydrogenase; catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid [Source:SGD;Acc:S000001699]" Bcin16g04120 127 Effector(V2)|Effector(V1) Methylated-DNA-[protein]-cysteine S-methyltransferase, active site + Winged helix-turn-helix DNA-binding domain + Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding Bcin16g04130 255 Ada DNA repair, metal-binding + Homeodomain-like + DNA binding HTH domain, AraC-type Bcin16g04140 343 SignalP-noTM//Effector(V2) Thaumatin Bcin16g04150 508 Protease Aspartic peptidase domain + Peptidase family A1 domain Bcin16g04160 573 CAZy : GH47 //SignalP-noTM Glycoside hydrolase, family 47 Bcin16g04170 1002 "Bcfar11, similar to yeast FAR11, Protein involved in recovery from cell cycle arrest; acts in response to pheromone; also involved in regulation of intra-S DNA damage checkpoint and autophagy; is essential for dephosphorylation of Atg13p; interacts with Far3p, Far7p, Far8p, Far9p, Far10p and with the phosphatases Pph21p, Pph22p and Pph3p; has similarity to the N- and C-termini of N. crassa HAM-2; similar to human Fam40A and Fam40B [Source:SGD;Acc:S000005071]" Bcin16g04180 609 Bcin16g04190 187 Effector(V1) Heterokaryon incompatibility Bcin16g04200 116 Effector(V2)|Effector(V1) Zinc finger, MYND-type Bcin16g04210 344 SignalP-noTM Bcidl1, Intradiol dioxygenase-like , extracellular dioxygenase Bcin16g04220 449 F-box domain + Leucine-rich repeat domain, L domain-like Bcin16g04230 119 Effector(V2)|Effector(V1) Cysteine-rich transmembrane CYSTM domain Bcin16g04240 355 "Bcmrpl7, similar to yeast MRPL7, Mitochondrial ribosomal protein of the large subunit; MRPL7 produces both YmL5 and YmL7, which are two different modified forms of the same protein [Source:SGD;Acc:S000002645]" Bcin16g04250 826 Protease PAN2 domain + Ubiquitin specific protease domain Bcin16g04260 859 Bcin16g04270 498 Bcin16g04280 262 Methyltransferase domain + S-adenosyl-L-methionine-dependent methyltransferase Bcin16g04290 319 Transporter "Bcflx1, similar to yeast FLX1, Protein required for transport of flavin adenine dinucleotide (FAD); a synthesis product of riboflavin, across the mitochondrial membrane [Source:SGD;Acc:S000001396]" Bcin16g04300 52 Effector(V1) "Bctom7, similar to yeast TOM7, Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex [Source:SGD;Acc:S000005014]" Bcin16g04310 380 "Bchsh49, similar to yeast HSH49, U2-snRNP associated splicing factor; similar to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM) [Source:SGD;Acc:S000005846]" Bcin16g04320 876 "Bcsto1, similar to yeast STO1, Large subunit of the nuclear mRNA cap-binding protein complex; interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80 [Source:SGD;Acc:S000004732]" Bcin16g04330 398 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Protein kinase, ATP binding site Bcin16g04340 356 "Bctom40, similar to yeast TOM40, Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; constitutes the core element of the protein conducting pore; pre-Tom40p is phosphorylated by PKA, which impairs its import into mitochondria under non-respiratory conditions [Source:SGD;Acc:S000004816]" Bcin16g04350 553 Fructose-2,6-bisphosphatase + Histidine phosphatase superfamily, clade-1 + 6-phosphofructo-2-kinase + P-loop containing nucleoside triphosphate hydrolase + Histidine phosphatase superfamily Bcin16g04360 481 Bcin16g04370 748 Bcin16g04380 341 Bcin16g04390 651 Bcin16g04400 621 Zinc finger, FYVE/PHD-type + Zinc finger, RING/FYVE/PHD-type + Zinc finger, PHD-finger + Transcription factor NFX1 family Bcin16g04410 932 Bcin16g04420 694 Bcin16g04430 200 Effector(V2)|Effector(V1) Bcin16g04440 641 "Bcitt1, similar to yeast ITT1, Protein that modulates the efficiency of translation termination; interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins [Source:SGD;Acc:S000004533]" Bcin16g04450 232 Phosphatidic acid phosphatase type 2/haloperoxidase Bcin16g04460 932 Protease//SignalP-noTM Peptidase S8/S53 domain + Peptidase S8A, DUF1034 C-terminal + Peptidase S8, subtilisin-related + Peptidase S8, subtilisin, His-active site + Peptidase S8, subtilisin, Asp-active site + Peptidase S8, subtilisin, Ser-active site Bcin16g04470 373 Bcin16g04480 1105 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain + Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal + Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 + NAD(P)-binding domain + NAD(P) transhydrogenase, alpha subunit, C-terminal + NAD(P) transhydrogenase, alpha subunit + DHS-like NAD/FAD-binding domain + NADP transhydrogenase beta-like domain Bcin16g04490 537 Ribonuclease III domain Bcin16g04500 963 Bcin16g04520 835 Aspartic peptidase domain Bcin16g04530 144 Effector(V2)|Effector(V1) Ribonuclease III domain Bcin16g04540 1095 Growth-arrest-specific protein 2 domain Bcin16g04550 527 SignalP-noTM Bcin16g04560 387 Glucose/ribitol dehydrogenase + NAD(P)-binding domain Bcin16g04570 101 Effector(V2)|Effector(V1) Bcin16g04580 417 Protein of unknown function DUF1640 Bcin16g04590 387 Bcin16g04600 421 Bcin16g04610 257 Effector(V1) Marvel domain Bcin16g04620 62 Effector(V2)|Effector(V1) Bcin16g04630 261 SignalP-noTM//SignalP& 0TM& >3cys& Len<300aa Bcin16g04640 437 "Bcfdh1, similar to yeast FDH1, NAD(+)-dependent formate dehydrogenase; may protect cells from exogenous formate [Source:SGD;Acc:S000005915]" Bcin16g04650 556 Bcin16g04660 470 Bcin16g04670 794 "Bcnop4, similar to yeast NOP4, Nucleolar protein; essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; contains four RNA recognition motifs (RRMs) [Source:SGD;Acc:S000005964]" Bcin16g04680 360 Mediator complex, subunit Med19, fungi Bcin16g04690 290 SignalP-noTM Translocon-associated protein (TRAP), alpha subunit Bcin16g04700 190 Bcin16g04710 598 "Bctup1, similar to yeast TUP1, General repressor of transcription; forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes [Source:SGD;Acc:S000000680]" Bcin16g04720 348 "Bcerg3, similar to yeast ERG3, C-5 sterol desaturase; glycoprotein that catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; mutants are viable, but cannot grow on non-fermentable carbon sources; substrate of the HRD ubiquitin ligase [Source:SGD;Acc:S000004046]" Bcin16g04730 431 "Bcser1, similar to yeast SER1, 3-phosphoserine aminotransferase; catalyzes the formation of phosphoserine from 3-phosphohydroxypyruvate, required for serine and glycine biosynthesis; regulated by the general control of amino acid biosynthesis mediated by Gcn4p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005710]" Bcin16g04740 525 Zinc finger, MIZ-type + Zinc finger, RING/FYVE/PHD-type + PINIT domain + E3 SUMO protein ligase Bcin16g04750 133 Effector(V1) Uncharacterised protein family UPF0642 Bcin16g04760 864 "Bclas21, similar to yeast LAS21, Integral plasma membrane protein; involved in the synthesis of the glycosylphosphatidylinositol (GPI) core structure; mutations affect cell wall integrity [Source:SGD;Acc:S000003598]" Bcin16g04770 243 Bcin16g04780 795 Conserved oligomeric Golgi complex subunit 1 Bcin16g04790 1338 Glucose-methanol-choline oxidoreductase, N-terminal + Glucose-methanol-choline oxidoreductase, C-terminal + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain + Alpha/Beta hydrolase fold Bcin16g04800 333 Lactate/malate dehydrogenase, N-terminal + Malate dehydrogenase, active site + L-lactate/malate dehydrogenase + Malate dehydrogenase, type 1 + Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal + NAD(P)-binding domain + Lactate/malate dehydrogenase, C-terminal Bcin16g04810 150 Effector(V1) Ribosomal protein L28e + Ribosomal L28e/Mak16 Bcin16g04820 132 Effector(V2)|Effector(V1) Protein of unknown function DUF2015 Bcin16g04830 203 Effector(V2)|Effector(V1) "Bctrs33, similar to yeast TRS33, Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII) [Source:SGD;Acc:S000005641]" Bcin16g04840 254 Bcin16g04850 374 Protease Peptidase S54, rhomboid domain Bcin16g04860 575 Transporter Sugar/inositol transporter + General substrate transporter + Sugar transporter, conserved site + Major facilitator superfamily domain Bcin16g04870 662 Uncharacterised conserved protein UCP014753 Bcin16g04880 498 Bcin16g04890 444 Bcin16g04900 528 Bcin16g04910 1766 yes BcSep1, Formin bni1 Bcin16g04920 196 Effector(V1) Bcin16g04930 218 Effector(V2)|Effector(V1) Zinc finger, RING-type + Zinc finger, RING/FYVE/PHD-type Bcin16g04940 664 Effector(V2) Bcin16g04950 344 Checkpoint protein Hus1/Mec3 Bcin16g04960 1453 Bcin16g04970 661 Bcin16g04980 216 Effector(V1) Bcin16g04990 393 SignalP-noTM Bcin16g05000 567 Protein kinase domain + Serine-threonine/tyrosine-protein kinase catalytic domain + Protein kinase-like domain + Prion-inhibition and propagation, HeLo domain Bcin16g05010 1391 Protein kinase domain + Serine/threonine-protein kinase, active site + Protein kinase-like domain + Ankyrin repeat-containing domain Bcin16g05020 508 Cytochrome P450 + Cytochrome P450, E-class, group I + Cytochrome P450, conserved site Bcin16g05030 410 Amidohydrolase 1 + Metal-dependent hydrolase Bcin16g05040 2575 SM cluster PKS16 (KE)//Protease Bcpks16, Polyketide synthase Bcin16g05050 510 SM cluster PKS16//SignalP-noTM FAD linked oxidase, N-terminal + FAD-binding, type 2 + FAD-binding, type 2, subdomain 1 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 Bcin16g05060 539 Bcin16g05070 1344 Transporter "Bcneo1, similar to yeast NEO1, Putative aminophospholipid translocase (flippase); involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus [Source:SGD;Acc:S000001310]" Bcin16g05080 1997 Ancestral coatomer element 1, Sec16/Sec31 + Sec16, central conserved domain + Sec16, N-terminal + COPII coat assembly protein, Sec16 Bcin16g05090 1414 Signal transduction response regulator, receiver domain + Histidine kinase-like ATPase, C-terminal domain + Signal transduction histidine kinase EnvZ-like, dimerisation/phosphoacceptor domain + Signal transduction histidine kinase-related protein, C-terminal + Signal transduction histidine kinase, core + CheY-like superfamily + GAF domain-like Bcin16g05100 411 Monooxygenase, FAD-binding + Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain Bcin16g05110 97 Bcin16g05120 574 "Bcmss1, similar to yeast MSS1, Mitochondrial protein; forms a heterodimer complex with Mto1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; similar to human GTPBP3 [Source:SGD;Acc:S000004625]" Bcin16g05130 380 Bcin16g05140 839 "Bcgyp7, similar to yeast GYP7, GTPase-activating protein for yeast Rab family members; members include Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking [Source:SGD;Acc:S000002393]" Bcin16g05150 290 Bcin16g05160 486 Bcin16g05170 290 Kinase phosphorylation domain Bcin16g05180 1753 Histidine kinase-like ATPase, C-terminal domain + Protein of unknown function DUF3684 Bcin16g05190 362 Effector(V2) Alcohol dehydrogenase, zinc-type, conserved site + GroES (chaperonin 10)-like + Alcohol dehydrogenase, C-terminal + Alcohol dehydrogenase GroES-like + NAD(P)-binding domain + Polyketide synthase, enoylreductase domain Bcin16g05195 207 Protease//SignalP-noTM Phosphatidylethanolamine-binding protein PEBP Bcin16g05196 249 Bcin16g05198 431 Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin16g05200 836 Glycoside hydrolase, family 32 + Glycosyl hydrolase family 32, N-terminal + Glycosyl hydrolase family 32, C-terminal + Concanavalin A-like lectin/glucanase domain + Glycosyl hydrolase, five-bladed beta-propellor domain Bcin17g00010 427 Aminotransferases, class-I, pyridoxal-phosphate-binding site + Aminotransferase, class I/classII + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + Pyridoxal phosphate-dependent transferase, major region, subdomain 2 + Pyridoxal phosphate-dependent transferase Bcin17g00020 360 UbiA prenyltransferase family Bcin17g00030 350 Bcin17g00040 312 Alpha/beta hydrolase fold-1 + Alpha/Beta hydrolase fold Bcin17g00050 754 AMP-dependent synthetase/ligase + Acyl carrier protein-like + AMP-binding, conserved site Bcin17g00060 558 Protein kinase domain + Protein kinase-like domain + Calcium/calmodulin-dependent/calcium-dependent protein kinase Bcin17g00065 200 Bcin17g00070 1133 Protease Peptidase C48, SUMO/Sentrin/Ubl1 Bcin17g00090 531 Bcin17g00110 602 DnaJ domain Bcin17g00120 512 Bcin17g00130 715 Bcin17g00140 310 Bcin17g00150 566 Bcin17g00160 77 Bcin17g00170 333 Bcin17g00180 275 Effector(V2) Bcin17g00230 910 Peptidase C48, SUMO/Sentrin/Ubl1 Bcin18g00010 412 Bcin18g00020 402 NADH:flavin oxidoreductase/NADH oxidase, N-terminal + Aldolase-type TIM barrel Bcin18g00040 179 Bcin18g00060 1217 Protease Peptidase C48, SUMO/Sentrin/Ubl1 Bcin18g00090 146 Bcin18g00110 605 Bcin18g00120 194 Bcin18g00130 80 Effector(V1) Bcin18g00135 401 Bcin18g00140 688 Bcin18g00145 90 Bcin18g00150 644 DnaJ domain Bcin18g00160 577 Bcin18g00170 668 Bcin18g00180 440 Bcin18g00190 313